Michael Willis

Michael Willis

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Michael Willis

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Cyclic Alkenylsulfonyl Fluorides: Palladium-Catalyzed Synthesis and Functionalization of Compact Multi-functional Reagents.

Angew Chem Int Ed Engl 2019 Oct 15. Epub 2019 Oct 15.

University of Oxford, Organic Chemistry, Chemistry Research Laboratory, Mansfield Road, OX1 3TA, Oxford, UNITED KINGDOM.

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http://dx.doi.org/10.1002/anie.201910871DOI Listing
October 2019

Modular Sulfondiimine Synthesis Using a Stable Sulfinylamine Reagent.

J Am Chem Soc 2019 Aug 9;141(33):13022-13027. Epub 2019 Aug 9.

Department of Chemistry, Chemistry Research Laboratory , University of Oxford , Mansfield Road , Oxford OX1 3TA , United Kingdom.

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http://dx.doi.org/10.1021/jacs.9b06831DOI Listing
August 2019

A rhodium-catalysed Sonogashira-type coupling exploiting C-S functionalisation: orthogonality with palladium-catalysed variants.

Chem Commun (Camb) 2019 Feb;55(19):2757-2760

Department of Chemistry, University of Oxford, Chemistry Research Laboratory, Mansfield Road, Oxford, OX1 3TA, UK.

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http://dx.doi.org/10.1039/c9cc00092eDOI Listing
February 2019

Heterocyclic Allylsulfones as Latent Heteroaryl Nucleophiles in Palladium-Catalyzed Cross-Coupling Reactions.

J Am Chem Soc 2018 11 9;140(46):15916-15923. Epub 2018 Nov 9.

Department of Chemistry, Chemistry Research Laboratory , University of Oxford , Mansfield Road , Oxford OX1 3TA , U.K.

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http://dx.doi.org/10.1021/jacs.8b09595DOI Listing
November 2018

Copper-catalysed synthesis of alkylidene 2-pyrrolinone derivatives from the combination of α-keto amides and alkynes.

Org Biomol Chem 2018 10;16(42):7797-7800

Department of Chemistry, University of Oxford, Chemistry Research Laboratory, Mansfield Road, Oxford, OX1 3TA, UK.

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http://dx.doi.org/10.1039/c8ob02205dDOI Listing
October 2018

Copper-Catalyzed Synthesis of Activated Sulfonate Esters from Boronic Acids, DABSO, and Pentafluorophenol.

Org Lett 2018 09 28;20(17):5493-5496. Epub 2018 Aug 28.

Department of Chemistry , University of Oxford, Chemistry Research Laboratory , Mansfield Road , Oxford OX1 3TA , United Kingdom.

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http://dx.doi.org/10.1021/acs.orglett.8b02445DOI Listing
September 2018

Shaker-related voltage-gated potassium channels Kv1 in human hippocampus.

Brain Struct Funct 2018 Jul 21;223(6):2663-2671. Epub 2018 Mar 21.

Division of Molecular and Cellular Pharmacology, Department of Medical Genetics, Molecular and Clinical Pharmacology, Medical University Innsbruck, Peter Mayr Strasse 1, 6020, Innsbruck, Austria.

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http://dx.doi.org/10.1007/s00429-018-1653-xDOI Listing
July 2018

Direct Copper-Catalyzed Three-Component Synthesis of Sulfonamides.

J Am Chem Soc 2018 07 2;140(28):8781-8787. Epub 2018 Jul 2.

Department of Chemistry, Chemistry Research Laboratory , University of Oxford , Mansfield Road , Oxford OX1 3TA , United Kingdom.

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http://dx.doi.org/10.1021/jacs.8b04532DOI Listing
July 2018

Rh(DPEPhos)-Catalyzed Alkyne Hydroacylation Using β-Carbonyl-Substituted Aldehydes: Mechanistic Insight Leads to Low Catalyst Loadings that Enables Selective Catalysis on Gram-Scale.

J Am Chem Soc 2018 06 29;140(23):7347-7357. Epub 2018 May 29.

Department of Chemistry, Chemistry Research Laboratories , University of Oxford , Mansfield Road , Oxford OX1 4TA , U.K.

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http://dx.doi.org/10.1021/jacs.8b04086DOI Listing
June 2018

Direct sulfonylation of anilines mediated by visible light.

Chem Sci 2018 Jan 16;9(3):629-633. Epub 2017 Nov 16.

Department of Chemistry , University of Oxford , Chemical Research Laboratory , Mansfield Road , Oxford , OX1 3TA , UK . Email: ; Email: ; Email: ; Email: ; Email:

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http://dx.doi.org/10.1039/c7sc03891gDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5868301PMC
January 2018

Exploiting rhodium-catalysed ynamide hydroacylation as a platform for divergent heterocycle synthesis.

Chem Sci 2017 Dec 5;8(12):7963-7968. Epub 2017 Oct 5.

Department of Chemistry , University of Oxford , Chemistry Research Laboratory , Mansfield Road , Oxford , OX1 3TA , UK . Email:

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http://dx.doi.org/10.1039/c7sc03795cDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5853270PMC
December 2017

One-Pot, Three-Component Sulfonimidamide Synthesis Exploiting the Sulfinylamine Reagent N-Sulfinyltritylamine, TrNSO.

Angew Chem Int Ed Engl 2017 11 10;56(47):14937-14941. Epub 2017 Oct 10.

Department of Chemistry, University of Oxford, Chemistry Research Laboratory, Mansfield Road, Oxford, OX1 3TA, UK.

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http://dx.doi.org/10.1002/anie.201708590DOI Listing
November 2017

Catalyst Selection Facilitates the Use of Heterocyclic Sulfinates as General Nucleophilic Coupling Partners in Palladium-Catalyzed Coupling Reactions.

Org Lett 2017 11 18;19(22):6033-6035. Epub 2017 Oct 18.

Department of Chemistry, University of Oxford, Chemistry Research Laboratory , Mansfield Road, Oxford OX1 3TA, U.K.

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http://dx.doi.org/10.1021/acs.orglett.7b02944DOI Listing
November 2017

A Copper(I)-Catalyzed Addition/Annulation Sequence for the Two-Component Synthesis of γ-Ylidenebutenolides.

Org Lett 2017 09 15;19(17):4556-4559. Epub 2017 Aug 15.

Department of Chemistry, University of Oxford, Chemistry Research Laboratory , Mansfield Road, Oxford, OX1 3TA, U.K.

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http://dx.doi.org/10.1021/acs.orglett.7b02151DOI Listing
September 2017

Exploiting Carbonyl Groups to Control Intermolecular Rhodium-Catalyzed Alkene and Alkyne Hydroacylation.

J Am Chem Soc 2017 07 17;139(29):10142-10149. Epub 2017 Jul 17.

Department of Chemistry, Chemistry Research Laboratory, University of Oxford , Mansfield Road, Oxford OX1 3TA, U.K.

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http://dx.doi.org/10.1021/jacs.7b05713DOI Listing
July 2017

Pyridine sulfinates as general nucleophilic coupling partners in palladium-catalyzed cross-coupling reactions with aryl halides.

Chem Sci 2017 Jun 28;8(6):4437-4442. Epub 2017 Apr 28.

Department of Chemistry , University of Oxford , Chemical Research Laboratory , Mansfield Road , Oxford , OX1 3TA , UK . Email:

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http://dx.doi.org/10.1039/c7sc00675fDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5590096PMC
June 2017

Enantioselective Three-Component Assembly of β'-Aryl Enones Using a Rhodium-Catalyzed Alkyne Hydroacylation/Aryl Boronic Acid Conjugate Addition Sequence.

Org Lett 2017 05 9;19(10):2734-2737. Epub 2017 May 9.

Chemistry Research Laboratory, Department of Chemistry, University of Oxford , Mansfield Road, Oxford OX1 3TA, U.K.

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http://dx.doi.org/10.1021/acs.orglett.7b01087DOI Listing
May 2017

Copper(i)-catalyzed sulfonylative Suzuki-Miyaura cross-coupling.

Chem Sci 2017 Apr 28;8(4):3249-3253. Epub 2017 Feb 28.

Department of Chemistry , University of Oxford , Chemical Research Laboratory , Mansfield Road , Oxford , OX1 3TA , UK . Email:

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http://dx.doi.org/10.1039/c6sc05483hDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5424447PMC
April 2017

Small-conductance calcium-activated potassium type 2 channels (SK2, KCa2.2) in human brain.

Brain Struct Funct 2017 03 29;222(2):973-979. Epub 2016 Jun 29.

Division of Molecular and Cellular Pharmacology, Medical University Innsbruck, Peter Mayr Strasse 1, 6020, Innsbruck, Austria.

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http://dx.doi.org/10.1007/s00429-016-1258-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5334391PMC
March 2017

Validation of the Economic and Health Outcomes Model of Type 2 Diabetes Mellitus (ECHO-T2DM).

Pharmacoeconomics 2017 03;35(3):375-396

The Swedish Institute for Health Economics, Box 2127, SE-220 02, Lund, Sweden.

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http://dx.doi.org/10.1007/s40273-016-0471-3DOI Listing
March 2017

One-pot palladium-catalyzed synthesis of sulfonyl fluorides from aryl bromides.

Chem Sci 2017 Feb 11;8(2):1233-1237. Epub 2016 Oct 11.

Department of Chemistry , University of Oxford , Chemical Research Laboratory , Mansfield Road , Oxford , OX1 3TA , UK . Email:

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http://dx.doi.org/10.1039/c6sc03924cDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5369543PMC
February 2017

Sequential catalysis: exploiting a single rhodium(i) catalyst to promote an alkyne hydroacylation-aryl boronic acid conjugate addition sequence.

Chem Sci 2017 Jan 9;8(1):536-540. Epub 2016 Sep 9.

Department of Chemistry , University of Oxford , Chemical Research Laboratory , Mansfield Road , Oxford , OX1 3TA , UK . Email:

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http://dx.doi.org/10.1039/c6sc03066aDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5351800PMC
January 2017

Two-Component Assembly of Thiochroman-4-ones and Tetrahydrothiopyran-4-ones Using a Rhodium-Catalyzed Alkyne Hydroacylation/Thio-Conjugate-Addition Sequence.

Org Lett 2016 11 25;18(21):5676-5679. Epub 2016 Oct 25.

Department of Chemistry, University of Oxford, Chemistry Research Laboratory , Mansfield Road, Oxford, OX1 3TA, U.K.

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http://dx.doi.org/10.1021/acs.orglett.6b02909DOI Listing
November 2016

Traceless Rhodium-Catalyzed Hydroacylation Using Alkyl Aldehydes: The Enantioselective Synthesis of β-Aryl Ketones.

Chemistry 2016 Oct 26;22(44):15624-15628. Epub 2016 Sep 26.

Department of Chemistry, University of Oxford, Chemistry Research Laboratory, Mansfield Road, Oxford, OX1 3TA, UK.

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http://dx.doi.org/10.1002/chem.201604035DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5396316PMC
October 2016

A Systematic Review of Cost-Effectiveness Models in Type 1 Diabetes Mellitus.

Pharmacoeconomics 2016 06;34(6):569-85

The Swedish Institute for Health Economics, IHE, Lund, Sweden.

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http://dx.doi.org/10.1007/s40273-015-0374-8DOI Listing
June 2016

Direct Synthesis of Highly Substituted Pyrroles and Dihydropyrroles Using Linear Selective Hydroacylation Reactions.

Chemistry 2016 06 23;22(23):7879-84. Epub 2016 Apr 23.

Department of Chemistry, University of Oxford, Mansfield Road, Oxford, OX1 3TA, UK.

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http://dx.doi.org/10.1002/chem.201600311DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5074311PMC
June 2016

Homogeneous rhodium(i)-catalysis in de novo heterocycle syntheses.

Org Biomol Chem 2016 Jun 20;14(22):4986-5000. Epub 2016 May 20.

Department of Chemistry, Chemistry Research Laboratory, University of Oxford, Mansfield Road, Oxford, OX1 3TA, UK.

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http://dx.doi.org/10.1039/c6ob00835fDOI Listing
June 2016

One-Pot Sulfoxide Synthesis Exploiting a Sulfinyl-Dication Equivalent Generated from a DABSO/Trimethylsilyl Chloride Sequence.

Org Lett 2016 05 15;18(9):2086-9. Epub 2016 Apr 15.

Department of Chemistry, University of Oxford , Chemistry Research Laboratory, Mansfield Road, Oxford, OX1 3TA, United Kingdom.

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http://dx.doi.org/10.1021/acs.orglett.6b00712DOI Listing
May 2016

Diversely Substituted Quinolines via Rhodium-Catalyzed Alkyne Hydroacylation.

Org Lett 2016 Apr 14;18(7):1562-5. Epub 2016 Mar 14.

Department of Chemistry, University of Oxford, Chemistry Research Laboratory , Mansfield Road, Oxford, OX1 3TA, U.K.

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http://dx.doi.org/10.1021/acs.orglett.6b00390DOI Listing
April 2016

α-Amino Aldehydes as Readily Available Chiral Aldehydes for Rh-Catalyzed Alkyne Hydroacylation.

J Am Chem Soc 2016 Feb 28;138(5):1630-4. Epub 2016 Jan 28.

Department of Chemistry, Chemistry Research Laboratory, University of Oxford , Mansfield Road, Oxford, OX1 3TA, U.K.

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http://dx.doi.org/10.1021/jacs.5b11892DOI Listing
February 2016

Palladium(II)-Catalyzed Synthesis of Sulfinates from Boronic Acids and DABSO: A Redox-Neutral, Phosphine-Free Transformation.

Angew Chem Int Ed Engl 2016 Jan 24;55(2):747-50. Epub 2015 Nov 24.

Department of Chemistry, University of Oxford, Chemistry Research Laboratory, Mansfield Road, Oxford, OX1 3TA (UK) http://mcwillis.chem.ox.ac.uk/MCW/Home.html.

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http://dx.doi.org/10.1002/anie.201508370DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4832823PMC
January 2016

Cost-Effectiveness of Canagliflozin versus Sitagliptin as Add-on to Metformin in Patients with Type 2 Diabetes Mellitus in Mexico.

Value Health Reg Issues 2015 Dec 3;8:8-19. Epub 2015 Jun 3.

Johnson and Johnson International, New Brunswick, NJ, USA.

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http://dx.doi.org/10.1016/j.vhri.2015.01.002DOI Listing
December 2015

An Aryne-Based Route to Substituted Benzoisothiazoles.

Org Lett 2015 Oct;17(19):4786-9

Department of Chemistry, University of Oxford, Chemistry Research Laboratory , Mansfield Road, Oxford, OX1 3TA, United Kingdom.

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http://dx.doi.org/10.1021/acs.orglett.5b02347DOI Listing
October 2015

Well-Defined and Robust Rhodium Catalysts for the Hydroacylation of Terminal and Internal Alkenes.

Angew Chem Int Ed Engl 2015 Jul 9;54(29):8520-4. Epub 2015 Jun 9.

Department of Chemistry, University of Oxford, Mansfield Road, Oxford, OX1 3TA (UK).

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http://dx.doi.org/10.1002/anie.201503208DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4531818PMC
July 2015

Recharge of a subglacial lake by surface meltwater in northeast Greenland.

Nature 2015 Feb 21;518(7538):223-7. Epub 2015 Jan 21.

Lamont-Doherty Earth Observatory of Columbia University, Palisades, New York 10964, USA.

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http://dx.doi.org/10.1038/nature14116DOI Listing
February 2015

Combining organometallic reagents, the sulfur dioxide surrogate DABSO, and amines: a one-pot preparation of sulfonamides, amenable to array synthesis.

Angew Chem Int Ed Engl 2015 Jan 27;54(4):1168-71. Epub 2014 Nov 27.

Department of Chemistry, University of Oxford, Chemistry Research Laboratory, Mansfield Road, Oxford, OX1 3TA (UK) http://mcwillis.chem.ox.ac.uk/MCW/Home.html.

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http://dx.doi.org/10.1002/anie.201409283DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4312890PMC
January 2015

Palladium-catalyzed synthesis of ammonium sulfinates from aryl halides and a sulfur dioxide surrogate: a gas- and reductant-free process.

Angew Chem Int Ed Engl 2014 Sep 27;53(38):10204-8. Epub 2014 Jul 27.

Department of Chemistry, University of Oxford, Chemistry Research Laboratory, Mansfield Road, Oxford, OX1 3TA (UK) http://mcwillis.chem.ox.ac.uk/MCW/Home.html.

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http://dx.doi.org/10.1002/anie.201404527DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4497614PMC
September 2014

DABSO-based, three-component, one-pot sulfone synthesis.

Org Lett 2014 Jan 5;16(1):150-3. Epub 2013 Dec 5.

Department of Chemistry, University of Oxford, Chemistry Research Laboratory , Mansfield Road, Oxford OX1 3TA, United Kingdom.

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http://dx.doi.org/10.1021/ol403122aDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3883144PMC
January 2014

2-Aminobenzaldehydes as versatile substrates for rhodium-catalyzed alkyne hydroacylation: application to dihydroquinolone synthesis.

Angew Chem Int Ed Engl 2013 Dec 12;52(50):13280-3. Epub 2013 Nov 12.

Department of Chemistry, University of Oxford, Chemistry Research Laboratory, Mansfield Road, Oxford, OX1 3TA (UK) http://mcwillis.chem.ox.ac.uk/MCW/Home.html.

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http://dx.doi.org/10.1002/anie.201308127DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4227557PMC
December 2013

Palladium-catalyzed three-component diaryl sulfone synthesis exploiting the sulfur dioxide surrogate DABSO.

Angew Chem Int Ed Engl 2013 Nov 2;52(48):12679-83. Epub 2013 Oct 2.

Department of Chemistry, University of Oxford, Chemistry Research Laboratory, Mansfield Road, Oxford, OX1 3TA (UK) http://mcwillis.chem.ox.ac.uk/MCW/Home.html.

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http://dx.doi.org/10.1002/anie.201305369DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4138993PMC
November 2013

Activating group recycling in action: a rhodium-catalyzed carbothiolation route to substituted isoquinolines.

Org Lett 2013 Oct 1;15(20):5162-5. Epub 2013 Oct 1.

Department of Chemistry, University of Oxford , Chemistry Research Laboratory, Mansfield Road, Oxford, OX1 3TA, U.K.

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http://dx.doi.org/10.1021/ol402650qDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3817538PMC
October 2013

Validation of economic and health outcomes simulation model of type 2 diabetes mellitus (ECHO-T2DM).

J Med Econ 2013 Aug 26;16(8):1007-21. Epub 2013 Jun 26.

The Swedish Institute for Health Economics, Lund, Sweden.

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http://dx.doi.org/10.3111/13696998.2013.809352DOI Listing
August 2013

Traceless chelation-controlled rhodium-catalyzed intermolecular alkene and alkyne hydroacylation.

Chemistry 2013 Feb 16;19(9):3125-30. Epub 2013 Jan 16.

Department of Chemistry, University of Oxford, Chemistry Research Laboratory, Mansfield Road, Oxford, OX1 3TA, UK.

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http://doi.wiley.com/10.1002/chem.201204056
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http://dx.doi.org/10.1002/chem.201204056DOI Listing
February 2013

Tandem inverse-electron-demand hetero-/retro-Diels-Alder reactions for aromatic nitrogen heterocycle synthesis.

Chem Soc Rev 2013 Jan 19;42(1):63-76. Epub 2012 Oct 19.

Department of Chemistry, University of Oxford, Chemistry Research Laboratory, Mansfield Road, Oxford, OX1 3TA, UK.

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http://dx.doi.org/10.1039/c2cs35316dDOI Listing
January 2013

Catalytic enantioselective desymmetrisation as a tool for the synthesis of hodgkinsine and hodgkinsine B.

Chemistry 2012 Dec 30;18(52):16754-64. Epub 2012 Nov 30.

Department of Chemistry, University of Oxford, Chemistry Research Laboratory, UK.

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http://dx.doi.org/10.1002/chem.201203150DOI Listing
December 2012

Palladium-catalyzed synthesis of benzimidazoles and quinazolinones from common precursors.

J Org Chem 2012 Nov 12;77(21):9473-86. Epub 2012 Oct 12.

Chemistry Research Laboratory, University of Oxford, 12 Mansfield Road, Oxford OX1 3TA, UK.

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http://dx.doi.org/10.1021/jo301805dDOI Listing
November 2012

Copper-catalyzed tandem C-N bond formation: an efficient annulative synthesis of functionalized cinnolines.

Angew Chem Int Ed Engl 2012 Jun 26;51(23):5718-22. Epub 2012 Apr 26.

Department of Chemistry, University of Oxford, Chemistry Research Laboratory, Mansfield Road, Oxford, OX1 3TA, UK.

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http://dx.doi.org/10.1002/anie.201201529DOI Listing
June 2012

Palladium-catalysed aminosulfonylation of aryl-, alkenyl- and heteroaryl halides: scope of the three-component synthesis of N-aminosulfonamides.

Org Biomol Chem 2012 May 12;10(20):4007-14. Epub 2012 Mar 12.

Department of Chemistry, University of Oxford, Chemistry Research Laboratory, Mansfield Road, Oxford, OX1 3TA, UK.

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http://dx.doi.org/10.1039/c2ob07034kDOI Listing
May 2012

Rhodium-catalysed linear-selective alkyne hydroacylation.

Chem Commun (Camb) 2012 May 22. Epub 2012 May 22.

Department of Chemistry, University of Oxford, Chemistry Research Laboratory, Mansfield Road, Oxford, OX1 3TA, UK.

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http://dx.doi.org/10.1039/c2cc32713aDOI Listing
May 2012

Intermolecular hydroacylation: high activity rhodium catalysts containing small-bite-angle diphosphine ligands.

J Am Chem Soc 2012 Mar 2;134(10):4885-97. Epub 2012 Mar 2.

Department of Chemistry, Inorganic Chemistry Laboratories, University of Oxford, South Parks Road, Oxford OX1 3QR, UK.

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http://dx.doi.org/10.1021/ja211649aDOI Listing
March 2012

Aryl methyl sulfides as substrates for rhodium-catalyzed alkyne carbothiolation: arene functionalization with activating group recycling.

J Am Chem Soc 2012 Feb 7;134(6):2906-9. Epub 2012 Feb 7.

Department of Chemistry, University of Oxford, Chemistry Research Laboratory, Mansfield Road, Oxford OX1 3TA, UK.

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http://dx.doi.org/10.1021/ja2108992DOI Listing
February 2012

An alkyne hydroacylation route to highly substituted furans.

Angew Chem Int Ed Engl 2011 Nov 20;50(45):10657-60. Epub 2011 Sep 20.

Department of Chemistry, University of Oxford, Chemistry Research Laboratory, Mansfield Road, Oxford, OX1 3TA, UK.

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http://dx.doi.org/10.1002/anie.201105795DOI Listing
November 2011

DABCO-bis(sulfur dioxide), DABSO, as a convenient source of sulfur dioxide for organic synthesis: utility in sulfonamide and sulfamide preparation.

Org Lett 2011 Sep 25;13(18):4876-8. Epub 2011 Aug 25.

Department of Chemistry, University of Oxford, Chemistry Research Laboratory, Mansfield Road, Oxford, OX1 3TA, UK.

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http://dx.doi.org/10.1021/ol201957nDOI Listing
September 2011

Catalytic enantioselective total synthesis of hodgkinsine B.

Angew Chem Int Ed Engl 2011 Sep 24;50(39):9116-9. Epub 2011 Aug 24.

Department of Chemistry, University of Oxford, Chemistry Research Laboratory, Mansfield Road, Oxford, OX1 3TA, UK.

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http://dx.doi.org/10.1002/anie.201103864DOI Listing
September 2011

Rhodium-catalyzed branched-selective alkyne hydroacylation: a ligand-controlled regioselectivity switch.

Angew Chem Int Ed Engl 2011 May 19;50(22):5134-8. Epub 2011 Apr 19.

Department of Chemistry, University of Oxford, Chemistry Research Laboratory, Mansfield Road, Oxford, OX1 3TA, UK.

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http://dx.doi.org/10.1002/anie.201100956DOI Listing
May 2011

Chromogranin peptides in brain diseases.

J Neural Transm (Vienna) 2011 May 30;118(5):727-35. Epub 2011 Apr 30.

Department of General Psychiatry, Medical University Innsbruck, Innsbruck, Austria.

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http://dx.doi.org/10.1007/s00702-011-0648-zDOI Listing
May 2011

O-substituted alkyl aldehydes for rhodium-catalyzed intermolecular alkyne hydroacylation: the utility of methylthiomethyl ethers.

Org Lett 2011 Mar 10;13(5):998-1000. Epub 2011 Feb 10.

Department of Chemistry, University of Oxford, Oxford, UK.

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http://dx.doi.org/10.1021/ol1030662DOI Listing
March 2011

The impact on schizophrenia-related hospital utilization and costs of switching to long-acting risperidone injections in Sweden.

Eur J Health Econ 2010 Dec 19;11(6):585-94. Epub 2010 Jan 19.

The Swedish Institute for Health Economics, Box 2127, 220 02, Lund, Sweden.

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http://link.springer.com/10.1007/s10198-009-0215-9
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http://dx.doi.org/10.1007/s10198-009-0215-9DOI Listing
December 2010

Palladium-catalyzed aminosulfonylation of aryl halides.

J Am Chem Soc 2010 Nov 28;132(46):16372-3. Epub 2010 Oct 28.

Department of Chemistry, University of Oxford, Chemistry Research Laboratory, Mansfield Road, Oxford OX1 3TA, UK.

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http://pubs.acs.org/doi/abs/10.1021/ja1081124
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http://dx.doi.org/10.1021/ja1081124DOI Listing
November 2010

Cascade palladium-catalyzed direct intramolecular arylation/alkene isomerization sequences: synthesis of indoles and benzofurans.

Angew Chem Int Ed Engl 2010 Oct;49(43):7958-62

Department of Chemistry, University of Oxford, Chemistry Research Laboratory, Mansfield Road, Oxford, OX1 3TA UK.

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http://dx.doi.org/10.1002/anie.201004097DOI Listing
October 2010

Rhodium-catalysed intermolecular alkyne hydroacylation: the enantioselective synthesis of α- and β-substituted ketones by kinetic resolution.

Chemistry 2010 Sep;16(36):10950-4

Department of Chemistry, University of Oxford, Chemistry Research Laboratory, Mansfield Road, Oxford, OX1 3TA UK.

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September 2010

Catalytic intramolecular ketone hydroacylation: enantioselective synthesis of phthalides.

Authors:
Michael C Willis

Angew Chem Int Ed Engl 2010 Aug;49(35):6026-7

Department of Chemistry, University of Oxford, Chemistry Research Laboratory, Mansfield Road, Oxford, OX1 3TA UK.

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http://dx.doi.org/10.1002/anie.201000159DOI Listing
August 2010

A case study of ex ante, value-based price and reimbursement decision-making: TLV and rimonabant in Sweden.

Eur J Health Econ 2010 Apr 29;11(2):195-203. Epub 2009 Jul 29.

The Swedish Institute of Health Economics (IHE), Box 2127, 220 02, Lund, Sweden.

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http://dx.doi.org/10.1007/s10198-009-0166-1DOI Listing
April 2010

Transition metal catalyzed alkene and alkyne hydroacylation.

Authors:
Michael C Willis

Chem Rev 2010 Feb;110(2):725-48

Department of Chemistry, University of Oxford, Chemistry Research Laboratory, Mansfield Road, Oxford OX1 3TA, UK.

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http://dx.doi.org/10.1021/cr900096xDOI Listing
February 2010

Enantioselective desymmetrizing palladium catalyzed carbonylation reactions: the catalytic asymmetric synthesis of quaternary carbon center containing 1,3-dienes.

Org Biomol Chem 2010 Feb 21;8(4):758-60. Epub 2009 Dec 21.

Department of Chemistry, University of Bath, Bath, UKBA2 7AY.

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http://dx.doi.org/10.1039/b923186bDOI Listing
February 2010

Palladium-catalyzed aryl halide carbonylation-intramolecular O-enolate acylation: efficient isocoumarin synthesis, including the synthesis of thunberginol A.

Chem Commun (Camb) 2009 Nov 19(44):6744-6. Epub 2009 Oct 19.

University of Oxford, Chemical Research Laboratory, Mansfield Road, Oxford, UKOX1 3TA.

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http://dx.doi.org/10.1039/b917839bDOI Listing
November 2009

Adipocyte fatty acid binding protein during refeeding of female patients with anorexia nervosa.

Eur J Nutr 2009 Oct 7;48(7):403-8. Epub 2009 May 7.

Department of Internal Medicine I, Medical University Innsbruck, Anichstrasse 35, 6020 Innsbruck, Austria.

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http://dx.doi.org/10.1007/s00394-009-0027-9DOI Listing
October 2009

Changing the local coordination environment in mono- and bi- nuclear lanthanide complexes through "click" chemistry.

Dalton Trans 2009 Aug 24(32):6283-5. Epub 2009 Jun 24.

School of Chemistry, University of Manchester, Oxford Road, Manchester, UK M13 9PL.

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http://dx.doi.org/10.1039/b911588aDOI Listing
August 2009

Cascade palladium-catalyzed alkenyl aminocarbonylation/ intramolecular aryl amidation: an annulative synthesis of 2-quinolones.

Org Lett 2009 Feb;11(3):583-6

Department of Chemistry, University of Oxford, Chemistry Research Laboratory, Mansfield Road, Oxford OX1 3TA, UK.

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http://dx.doi.org/10.1021/ol802624eDOI Listing
February 2009

Tandem copper-catalysed aryl and alkenyl amination reactions: the synthesis of N-functionalised indoles.

Org Biomol Chem 2009 Feb 9;7(3):432-4. Epub 2008 Dec 9.

Department of Chemistry, University of Oxford, Chemistry Research Laboratory, Mansfield Road, Oxford, UKOX1 3TA.

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http://dx.doi.org/10.1039/b817254dDOI Listing
February 2009

Catalytic enantioselective intermolecular hydroacylation: rhodium-catalyzed combination of beta-S-aldehydes and 1,3-disubstituted allenes.

J Am Chem Soc 2008 Dec;130(51):17232-3

Department of Chemistry, University of Oxford, Chemical Research Laboratory, Mansfield Road, Oxford, UK.

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December 2008

Rhodium-catalysed hydroacylation or reductive aldol reactions: a ligand dependent switch of reactivity.

Chem Commun (Camb) 2008 Oct 2(40):5025-7. Epub 2008 Sep 2.

Department of Chemistry, University of Oxford, Chemical Research Laboratory, Mansfield Road, Oxford, UK OX1 3TA.

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October 2008

Palladium-catalyzed alpha-arylation of oxindoles.

Org Lett 2008 Apr 6;10(7):1413-5. Epub 2008 Mar 6.

Department of Chemistry, University of Bath, Bath, BA2 7AY, United Kingdom.

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http://dx.doi.org/10.1021/ol800141tDOI Listing
April 2008

Down-regulation of BK channel expression in the pilocarpine model of temporal lobe epilepsy.

Brain Res 2008 Mar 18;1200:116-31. Epub 2008 Jan 18.

Department of Biological Sciences at the University of Texas at Brownsville/Texas Southmost College, 80 Fort Brown, Brownsville, Texas 78520, USA.

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http://dx.doi.org/10.1016/j.brainres.2008.01.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2346580PMC
March 2008

Palladium-catalysed N-annulation routes to indoles: the synthesis of indoles with sterically demanding N-substituents, including demethylasterriquinone A1.

Chem Commun (Camb) 2007 Dec 3(45):4764-6. Epub 2007 Sep 3.

Department of Chemistry, University of Oxford, Chemical Research Laboratory, Mansfield Road, Oxford, UK OX1 3TA.

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http://dx.doi.org/10.1039/b712227fDOI Listing
December 2007