Michael Wiesener

Michael Wiesener

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Michael Wiesener

Michael Wiesener

Publications by authors named "Michael Wiesener"

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Dissecting TSC2-mutated renal and hepatic angiomyolipomas in an individual with ARID1B-associated intellectual disability.

BMC Cancer 2019 May 10;19(1):435. Epub 2019 May 10.

Institute of Human Genetics, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Schwabachanlage 10, 91054, Erlangen, Germany.

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http://dx.doi.org/10.1186/s12885-019-5633-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6511147PMC
May 2019

Is Early Complement Activation in Renal Transplantation Associated with Later Graft Outcome?

Kidney Blood Press Res 2018 4;43(5):1488-1504. Epub 2018 Oct 4.

Department of Nephropathology, Institute of Pathology, Friedrich-Alexander-University (FAU) Erlangen-Nürnberg, Erlangen,

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https://www.karger.com/Article/FullText/494014
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http://dx.doi.org/10.1159/000494014DOI Listing
January 2019

FHR5 Binds to Laminins, Uses Separate C3b and Surface-Binding Sites, and Activates Complement on Malondialdehyde-Acetaldehyde Surfaces.

J Immunol 2018 04 26;200(7):2280-2290. Epub 2018 Feb 26.

Department of Infection Biology, Leibniz Institute for Natural Product Research and Infection Biology, 07745 Jena, Germany;

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http://dx.doi.org/10.4049/jimmunol.1701641DOI Listing
April 2018

Hypoxia-inducible factor-1α is a critical transcription factor for IL-10-producing B cells in autoimmune disease.

Nat Commun 2018 01 17;9(1):251. Epub 2018 Jan 17.

Department of Internal Medicine 3, Friedrich-Alexander-University Erlangen-Nürnberg (FAU) and Universitätsklinikum Erlangen, 91054, Erlangen, Germany.

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http://www.nature.com/articles/s41467-017-02683-x
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http://dx.doi.org/10.1038/s41467-017-02683-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5772476PMC
January 2018

HIF is not essential for suppression of experimental tumor growth by mTOR inhibition.

J Cancer 2017 1;8(10):1809-1817. Epub 2017 Jul 1.

Department of Nephrology and Hypertension, Friedrich-Alexander-Universität Erlangen-Nürnberg, 91054 Erlangen, Germany.

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http://dx.doi.org/10.7150/jca.16486DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5556644PMC
July 2017

Experience with belatacept rescue therapy in kidney transplant recipients.

Transpl Int 2016 Nov 14;29(11):1184-1195. Epub 2016 Sep 14.

Division of Nephrology, Department of Internal Medicine, Charité Campus Mitte, Berlin, Germany.

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http://dx.doi.org/10.1111/tri.12822DOI Listing
November 2016

Discordant Clinical Course of Vitamin-D-Hydroxylase (CYP24A1) Associated Hypercalcemia in Two Adult Brothers With Nephrocalcinosis.

Kidney Blood Press Res 2015 22;40(5):443-51. Epub 2015 Aug 22.

Department of Nephrology and Hypertension, Friedrich-Alexander Universitx00E4;t Erlangen-Nx00FC;rnberg, Erlangen-Nx00FC;rnberg, Germany.

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http://dx.doi.org/10.1159/000368520DOI Listing
August 2016

Complement Factor H-Related 5-Hybrid Proteins Anchor Properdin and Activate Complement at Self-Surfaces.

J Am Soc Nephrol 2016 05 2;27(5):1413-25. Epub 2015 Oct 2.

Department of Infection Biology, Leibniz Institute for Natural Product Research and Infection Biology, Jena, Germany; Friedrich Schiller University, Jena, Germany

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http://dx.doi.org/10.1681/ASN.2015020212DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4849819PMC
May 2016

Hypoxia inhibits nephrogenesis through paracrine Vegfa despite the ability to enhance tubulogenesis.

Kidney Int 2015 Dec 22;88(6):1283-1292. Epub 2015 Jul 22.

Department of Nephrology and Hypertension, Friedrich-Alexander University Erlangen-Nürnberg (FAU), Erlangen, Germany.

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http://dx.doi.org/10.1038/ki.2015.214DOI Listing
December 2015

Association of a coding polymorphism in Fc gamma receptor 2A and graft survival in re-transplant candidates.

Hum Immunol 2015 Oct 30;76(10):759-64. Epub 2015 Sep 30.

Department of Internal Medicine 5, Hematology and Oncology, Friedrich-Alexander University Erlangen-Nuremberg, Germany.

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http://dx.doi.org/10.1016/j.humimm.2015.09.034DOI Listing
October 2015

Hypoxia regulates the sperm associated antigen 4 (SPAG4) via HIF, which is expressed in renal clear cell carcinoma and promotes migration and invasion in vitro.

Mol Carcinog 2014 Dec 2;53(12):970-8. Epub 2013 Jul 2.

Department of Nephrology and Hypertension, University of Erlangen-Nuremberg, Erlangen, Germany; Nikolaus Fiebiger Center, University of Erlangen-Nuremberg, Erlangen, Germany.

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http://dx.doi.org/10.1002/mc.22065DOI Listing
December 2014

Renal fibrosis is the common feature of autosomal dominant tubulointerstitial kidney diseases caused by mutations in mucin 1 or uromodulin.

Kidney Int 2014 Sep 26;86(3):589-99. Epub 2014 Mar 26.

1] Department of Nephrology and Hypertension, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany [2] Nikolaus-Fiebiger-Center of Molecular Medicine, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.

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https://linkinghub.elsevier.com/retrieve/pii/S00852538153032
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http://dx.doi.org/10.1038/ki.2014.72DOI Listing
September 2014

The proteasome inhibitor bortezomib prevents lupus nephritis in the NZB/W F1 mouse model by preservation of glomerular and tubulointerstitial architecture.

Nephron Exp Nephrol 2012 26;120(2):e47-58. Epub 2012 Jan 26.

Nephropathology, Department of Pathology, University of Erlangen-Nürnberg, Erlangen, Germany.

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http://dx.doi.org/10.1159/000334955DOI Listing
September 2012

Predominance of TH2 cells and plasma cells in polyoma virus nephropathy: a role for humoral immunity?

Hum Pathol 2012 Sep 8;43(9):1453-62. Epub 2012 Mar 8.

Institute of Pathology, Nephropathology, Friedrich-Alexander-University Erlangen-Nuremberg, 91054 Erlangen, Germany.

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http://dx.doi.org/10.1016/j.humpath.2011.11.006DOI Listing
September 2012

Inhibition of prolyl hydroxylases increases erythropoietin production in ESRD.

J Am Soc Nephrol 2010 Dec 29;21(12):2151-6. Epub 2010 Nov 29.

Department of Nephrology and Hypertension, Friedrich-Alexander-University, Krankenhausstrasse 12, 91054 Erlangen, Germany. wanja.bernhardt@uk-erlangen

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http://dx.doi.org/10.1681/ASN.2010010116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3014028PMC
December 2010

Hypoxia interferes with connective tissue growth factor (CTGF) gene expression in human proximal tubular cell lines.

Nephrol Dial Transplant 2009 Nov 23;24(11):3319-25. Epub 2009 Jun 23.

Department of Nephrology and Hypertension, Medical Clinic 4, University Hospital of Erlangen-Nuremberg, 91054 Erlangen, Germany.

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https://academic.oup.com/ndt/article-lookup/doi/10.1093/ndt/
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http://dx.doi.org/10.1093/ndt/gfp305DOI Listing
November 2009

Mutation analysis of hypoxia-inducible factors HIF1A and HIF2A in renal cell carcinoma.

Anticancer Res 2009 Nov;29(11):4337-43

Department of Medical and Molecular Genetics, University of Birmingham, Institute of Biomedical Research, Edgbaston, Birmingham, B15 2TT, UK.

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November 2009

The human HIF (hypoxia-inducible factor)-3alpha gene is a HIF-1 target gene and may modulate hypoxic gene induction.

Biochem J 2009 Oct 23;424(1):143-51. Epub 2009 Oct 23.

Department of Nephrology and Hypertension, University Clinic Erlangen, Loschgestrasse 8, D-91054 Erlangen, Germany.

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http://biochemj.org/lookup/doi/10.1042/BJ20090120
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http://dx.doi.org/10.1042/BJ20090120DOI Listing
October 2009

Novel insights into the role of the tumor suppressor von Hippel Lindau in cellular differentiation, ciliary biology, and cyst repression.

J Mol Med (Berl) 2009 Sep 24;87(9):871-7. Epub 2009 Jul 24.

Department of Nephrology and Hypertension, University of Erlangen-Nuremberg, Erlangen, Germany.

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http://link.springer.com/10.1007/s00109-009-0504-x
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http://dx.doi.org/10.1007/s00109-009-0504-xDOI Listing
September 2009

HIF-1 or HIF-2 induction is sufficient to achieve cell cycle arrest in NIH3T3 mouse fibroblasts independent from hypoxia.

Cell Cycle 2009 May 27;8(9):1386-95. Epub 2009 May 27.

Interdisciplinary Centre for Clinical Research (IZKF), University of Erlangen-Nuremberg, Erlangen, Germany.

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http://dx.doi.org/10.4161/cc.8.9.8306DOI Listing
May 2009

Key role for activin B in cellular transformation after loss of the von Hippel-Lindau tumor suppressor.

Mol Cell Biol 2009 Apr 21;29(7):1707-18. Epub 2009 Jan 21.

Nikolaus Fiebiger Center, University Erlangen-Nürnberg, Glückstr. 6, 91054 Erlangen, Germany.

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http://mcb.asm.org/cgi/doi/10.1128/MCB.01184-07
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http://dx.doi.org/10.1128/MCB.01184-07DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2655617PMC
April 2009

Role of hypoxia-inducible factor 1 alpha in the integrity of articular cartilage in murine knee joints.

Arthritis Res Ther 2008 12;10(5):R111. Epub 2008 Sep 12.

Division of Orthopaedic Rheumatology, University of Erlangen-Nuremberg, Rathsberger Strasse 57, Erlangen 91054, Germany.

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http://link.springer.com/content/pdf/10.1186/ar2508.pdf
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http://arthritis-research.com/content/10/5/R111
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http://dx.doi.org/10.1186/ar2508DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2592793PMC
February 2009

Mutual regulation of hypoxia-inducible factor and mammalian target of rapamycin as a function of oxygen availability.

Mol Cancer Res 2009 Jan;7(1):88-98

Interdisciplinary Centre for Clinical Research, Friedrich Alexander Universität Erlangen-Nürnberg, Nuremberg, Germany.

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http://dx.doi.org/10.1158/1541-7786.MCR-08-0288DOI Listing
January 2009

HIF activation protects from acute kidney injury.

J Am Soc Nephrol 2008 Mar 6;19(3):486-94. Epub 2008 Feb 6.

Medical Clinic 4, Department of Nephrology and Hypertension, Friedrich-Alexander-University Erlangen Nuremberg, Krankenhausstrasse 12, D - 91054 Erlangen, Germany.

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http://dx.doi.org/10.1681/ASN.2007040419DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2391048PMC
March 2008

Organ protection by hypoxia and hypoxia-inducible factors.

Methods Enzymol 2007 ;435:221-45

Department of Nephrology and Hypertension, Friedrich-Alexander University, Erlangen, Nürnberg, Germany.

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http://dx.doi.org/10.1016/S0076-6879(07)35012-XDOI Listing
February 2008

Hypoxia-inducible transcription factors and their role in renal disease.

Semin Nephrol 2007 May;27(3):363-72

Department of Nephrology and Hypertension, University of Erlangen-Nuernberg, Erlangen, Germany.

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http://medlib.yu.ac.kr/eur_j_oph/sem_nephrol/sem_n_pdf/SemNe
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http://linkinghub.elsevier.com/retrieve/pii/S027092950700038
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http://dx.doi.org/10.1016/j.semnephrol.2007.02.007DOI Listing
May 2007

Preconditional activation of hypoxia-inducible factors ameliorates ischemic acute renal failure.

J Am Soc Nephrol 2006 Jul 8;17(7):1970-8. Epub 2006 Jun 8.

Department of Nephrology and Hypertension, Nikolaus-Fiebiger-Center for Molecular Medicine, Friedrich-Alexander University Erlangen-Nuremberg, Loschgestrasse, Erlangen, Germany.

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http://dx.doi.org/10.1681/ASN.2005121302DOI Listing
July 2006

Inconsistent effects of acidosis on HIF-alpha protein and its target genes.

Pflugers Arch 2006 Jan 6;451(4):534-43. Epub 2005 Oct 6.

Department of Nephrology and Hypertension, Medizinische Klinik IV, University of Erlangen-Nuremberg, Germany.

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http://dx.doi.org/10.1007/s00424-005-1486-3DOI Listing
January 2006

Role of hypoxia in the pathogenesis of renal disease.

Kidney Int Suppl 2005 Dec(99):S46-51

Department of Nephrology and Hypertension, Friedrich-Alexander-University Erlangen-Nuremberg, Erlangen, Germany.

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http://dx.doi.org/10.1111/j.1523-1755.2005.09909.xDOI Listing
December 2005

Differentiating the functional role of hypoxia-inducible factor (HIF)-1alpha and HIF-2alpha (EPAS-1) by the use of RNA interference: erythropoietin is a HIF-2alpha target gene in Hep3B and Kelly cells.

FASEB J 2004 Sep 1;18(12):1462-4. Epub 2004 Jul 1.

Department of Nephrology and Medical Intensive Care, Virchow Clinic, Charité University Medicine, Berlin, Germany.

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http://dx.doi.org/10.1096/fj.04-1640fjeDOI Listing
September 2004

Role of hypoxia in the pathogenesis of renal disease.

Blood Purif 2003 ;21(3):253-7

Department of Nephrology and Medical Intensive Care, Charité, Humboldt University, Berlin, Germany.

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http://dx.doi.org/10.1159/000070698DOI Listing
March 2004

HIF and oxygen sensing; as important to life as the air we breathe?

Ann Med 2003 ;35(3):183-90

Renal Section, Imperial College London, UK.

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http://dx.doi.org/10.1080/0785389031000458233DOI Listing
October 2003

Cellular responses to hypoxia after renal segmental infarction.

Kidney Int 2003 Sep;64(3):874-86

Department of Nephrology and Medical Intensive Care, Charité, Humboldt University, Berlin, Germany.

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http://dx.doi.org/10.1046/j.1523-1755.2003.00159.xDOI Listing
September 2003

Activation of the hypoxia-inducible factor-pathway and stimulation of angiogenesis by application of prolyl hydroxylase inhibitors.

FASEB J 2003 Jun 22;17(9):1186-8. Epub 2003 Apr 22.

Department of Nephrology and Medical Intensive Care, Charité, Campus Virchow Clinic, Augustenburger Platz 1, 13353 Berlin, Germany.

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http://dx.doi.org/10.1096/fj.02-1062fjeDOI Listing
June 2003

Heterozygous deficiency of hypoxia-inducible factor-2alpha protects mice against pulmonary hypertension and right ventricular dysfunction during prolonged hypoxia.

J Clin Invest 2003 May;111(10):1519-27

Center for Transgene Technology and Gene Therapy, Flanders Interuniversity Institute for Biotechnology, Katholieke Universiteit Leuven, Leuven, Belgium.

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http://www.jci.org/articles/view/15496
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http://dx.doi.org/10.1172/JCI15496DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC155039PMC
May 2003

Involvement of a ferroprotein sensor in hypoxia-mediated inhibition of neutrophil apoptosis.

Blood 2002 Oct;100(8):3008-16

Respiratory Medicine Division, Department of Medicine, University of Cambridge School of Clinical Medicine, Addenbrooke's and Papworth Hospitals, Cambridge, United Kingdom.

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http://dx.doi.org/10.1182/blood-2002-02-0454DOI Listing
October 2002

Expression of hypoxia-inducible factor-1alpha and -2alpha in hypoxic and ischemic rat kidneys.

J Am Soc Nephrol 2002 Jul;13(7):1721-32

Department of Nephrology and Medical Intensive Care, Charité, Campus Virchow-Klinikum, Humboldt University, Augustenburger Platz 1, 13353 Berlin, Germany.

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http://dx.doi.org/10.1097/01.asn.0000017223.49823.2aDOI Listing
July 2002