Michael Weller

Michael Weller

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Michael Weller

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Predisposing and precipitating factors for delirium in neurology: a prospective cohort study of 1487 patients.

J Neurol 2019 Dec 13;266(12):3065-3075. Epub 2019 Sep 13.

Department of Consultation-Liaison Psychiatry and Psychosomatic Medicine, University Hospital Zurich, University of Zurich, Ramistrasse 100, 8091, Zurich, Switzerland.

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http://dx.doi.org/10.1007/s00415-019-09533-4DOI Listing
December 2019

Molecular targeted therapy of glioblastoma.

Cancer Treat Rev 2019 Nov 11;80:101896. Epub 2019 Sep 11.

Department of Neurology & Brain Tumor Center, University Hospital and University of Zurich, Zurich, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.ctrv.2019.101896DOI Listing
November 2019

Underweight and weight loss are predictors of poor outcome in patients with brain metastasis.

J Neurooncol 2019 Nov 30;145(2):339-347. Epub 2019 Sep 30.

Department of Neurology and Brain Tumor Center, University Hospital and University of Zurich, Frauenklinikstrasse 26, 8091, Zurich, Switzerland.

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http://dx.doi.org/10.1007/s11060-019-03300-1DOI Listing
November 2019

Romiplostim for temozolomide-induced thrombocytopenia in glioblastoma: The PLATUM trial.

Neurology 2019 Nov 4;93(19):e1799-e1806. Epub 2019 Oct 4.

From the General and Stereotaxic Neurosurgery Service, Neuro-oncology (E.L.R.), EA 2694-Santé Publique: Épidémiologie et Qualité des Soins (P.D.) and Onco thAI, INSERM U1189 (N.R.), Université de Lille, Research Federation (C.L.), and Department of Neurosurgery (N.R., F.D.), CHU Lille; Service de Neurologie 2-Mazarin, APHP, Sorbonne Université, IHU, ICM (C.H.), and Service de Neurologie 2-Mazarin (A.L.D.S.), Groupe Hospitalier Pitié-Salpêtrière, Paris; Service de Neuro-oncologie (S.C.), Hospices Civils de Lyon, Hôpital Neurologique; Service de Neuro-Oncologie (O.C.), Aix-Marseille University, AP-HM, CHU Timone, Marseille, France; and Department of Neurology & Brain Tumor Center (M.W.), University Hospital and University of Zurich, Switzerland.

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http://dx.doi.org/10.1212/WNL.0000000000008440DOI Listing
November 2019

Predisposing and precipitating risk factors for delirium in palliative care patients.

Palliat Support Care 2019 Nov 14:1-10. Epub 2019 Nov 14.

Department of Consultation-Liaison Psychiatry and Psychosomatic Medicine, University Hospital Zurich and University of Zurich, Zurich, Switzerland.

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http://dx.doi.org/10.1017/S1478951519000919DOI Listing
November 2019

Lymphatic outflow of cerebrospinal fluid is reduced in glioma.

Sci Rep 2019 Oct 15;9(1):14815. Epub 2019 Oct 15.

Institute of Pharmaceutical Sciences, Swiss Federal Institute of Technology, ETH Zurich, Zurich, Switzerland.

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http://dx.doi.org/10.1038/s41598-019-51373-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6794292PMC
October 2019

Synergistic growth inhibition mediated by dual PI3K/mTOR pathway targeting and genetic or direct pharmacological AKT inhibition in human glioblastoma models.

J Neurochem 2019 Oct 16. Epub 2019 Oct 16.

Laboratory of Molecular Neuro-Oncology, Department of Neurology, University Hospital and University of Zurich, Zurich, Switzerland.

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http://dx.doi.org/10.1111/jnc.14899DOI Listing
October 2019

Complementary and alternative medicine use in glioma patients in France.

J Neurooncol 2019 Oct 21. Epub 2019 Oct 21.

Department of Neurology, University Hospital and University of Zurich, Frauenklinikstrasse 26, 8091, Zurich, Switzerland.

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http://dx.doi.org/10.1007/s11060-019-03315-8DOI Listing
October 2019

Risk factors for the development of epilepsy in patients with brain metastasis.

Neuro Oncol 2019 Sep 10. Epub 2019 Sep 10.

Department of Neurology and Brain Tumor Center, University Hospital and University of Zurich, Frauenklinikstrasse, CH Zurich, Switzerland.

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https://academic.oup.com/neuro-oncology/advance-article/doi/
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http://dx.doi.org/10.1093/neuonc/noz172DOI Listing
September 2019

Therapeutic Targeting of TGFβ Ligands in Glioblastoma Using Novel Antisense Oligonucleotides Reduces the Growth of Experimental Gliomas.

Clin Cancer Res 2019 Sep 17. Epub 2019 Sep 17.

Laboratory of Molecular Neuro-Oncology, Department of Neurology, University Hospital Zurich and University of Zurich, Zurich, Switzerland.

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http://dx.doi.org/10.1158/1078-0432.CCR-17-3024DOI Listing
September 2019

Challenges in the diagnoses and treatment of CNS tumors.

Authors:
Michael Weller

Neurooncol Pract 2019 Sep 20;6(5):329. Epub 2019 Sep 20.

University Hospital Zurich, Department of Neurology, Switzerland.

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http://dx.doi.org/10.1093/nop/npz044DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6753350PMC
September 2019

EANO Guideline on the Diagnosis and Treatment of Vestibular Schwannoma.

Neuro Oncol 2019 Aug 28. Epub 2019 Aug 28.

Department of Neurosurgery Ludwig-Maximilians-Universität and DKTK partner site, University of Munich, Munich, Germany.

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http://dx.doi.org/10.1093/neuonc/noz153DOI Listing
August 2019

Profound, durable and MGMT-independent sensitivity of glioblastoma cells to cyclin-dependent kinase inhibition.

Int J Cancer 2019 07 12;145(1):242-253. Epub 2019 Jan 12.

Laboratory of Molecular Neuro-Oncology, Department of Neurology, University Hospital and University of Zurich, Zurich, Switzerland.

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https://onlinelibrary.wiley.com/doi/abs/10.1002/ijc.32069
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http://dx.doi.org/10.1002/ijc.32069DOI Listing
July 2019

Immunotherapy for glioblastoma: quo vadis?

Nat Rev Clin Oncol 2019 07;16(7):405-406

CHU Lille, Neuro-oncology, General and Stereotaxic Neurosurgery Service, Lille, France.

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http://dx.doi.org/10.1038/s41571-019-0195-3DOI Listing
July 2019

Management of low-grade glioma: a systematic review and meta-analysis.

Neurooncol Pract 2019 Jul 18;6(4):249-258. Epub 2018 Aug 18.

Department of Neurosurgery, Penn State Milton S. Hershey Medical Center, Hershey, Pennsylvania, USA.

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http://dx.doi.org/10.1093/nop/npy034DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6660818PMC
July 2019

[Update on primary brain tumours].

Ther Umsch 2018 ;75(7):438-443

1 Klinik für Neurologie und Hirntumorzentrum, UniversitätsSpital und Universität Zürich.

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http://dx.doi.org/10.1024/0040-5930/a001021DOI Listing
June 2019

In search of cerebrospinal fluid biomarkers of fatigue in multiple sclerosis: A proteomics study.

J Sleep Res 2019 Jun 1;28(3):e12721. Epub 2018 Jul 1.

Department of Neurology, University Hospital Zurich, University of Zurich, Zurich, Switzerland.

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http://dx.doi.org/10.1111/jsr.12721DOI Listing
June 2019

Ten-Year Outcomes of Moderately Hypofractionated (70 Gy in 28 fractions) Intensity Modulated Radiation Therapy for Localized Prostate Cancer.

Int J Radiat Oncol Biol Phys 2019 06 2;104(2):325-333. Epub 2019 Feb 2.

Department of Radiation Oncology, Taussig Cancer Institute, Cleveland Clinic, Cleveland, Ohio. Electronic address:

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http://dx.doi.org/10.1016/j.ijrobp.2019.01.091DOI Listing
June 2019

[Challenges and future perspectives in neuro-oncology].

Nervenarzt 2019 Jun;90(6):594-600

Neurologische Klinik, Hirntumorzentrum, UniversitätsSpital Zürich, Universität Zürich, Zürich, Schweiz.

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http://dx.doi.org/10.1007/s00115-019-0716-4DOI Listing
June 2019

Imaging necrosis during treatment is associated with worse survival in EORTC 26101 study.

Neurology 2019 Jun 10;92(24):e2754-e2763. Epub 2019 May 10.

From the University Medical Center & German Cancer Research Center (M.N., F.S., I.H., P.K., M.P., M.B., W.W.), Heidelberg, Germany; EORTC Headquarters (T.G., V.G.), Brussels, Belgium; Brain Tumor Center at Erasmus MC Cancer Institute (J.E.C.B., W.T., M.J.v.d.B.), Rotterdam, the Netherlands; Medical Oncology Department (A.A.B.), AUSL-Bologna-IRCCS Scienze Neurologiche, Bologna, Italy; Haaglanden Medical Center (M.J.B.T.), the Hague; Leiden University Medical Center (M.J.B.T.), the Netherlands; Institut Gustave Roussy (J.D.), Villejuif; Sorbonne Université (A.I.), Inserm, CNRS, UMR S 1127, Institut du Cerveau et de la Moelle Épinière, ICM, AP-HP, Hôpitaux Universitaires La Pitié Salpêtrière-Charles Foix, Service de Neurologie 2-Mazarin, Paris; Institut de Cancerologie de l'Ouest (ICO)-Centre Rene Gauducheau (M.C.), Saint-Herblain, France; Leuven Cancer Institute-KU Leuven (P.M.C.), Belgium; Department of Neurology and Brain Tumor Center (M.W.), University Hospital and University of Zurich, Switzerland; Institut Régional du Cancer Montpellier (M.F.); University of Lille (E.L.R.), U-1192, Inserm; CHU Lille (E.L.R.), General and Stereotaxic Neurosurgery Service; Oscar Lambret Center (E.L.R.), Neurology, Lille, France; Department of Neurology (M.P.), Medical Faculty Mannheim, Heidelberg University, Germany; and Department of Neurology (M.N.), Medical University Innsbruck, Austria.

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http://dx.doi.org/10.1212/WNL.0000000000007643DOI Listing
June 2019

Data Sets for the Reporting of Tumors of the Central Nervous System.

Arch Pathol Lab Med 2019 Jun 20. Epub 2019 Jun 20.

From the Department of Pathology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts (Dr Louis); the Department of Pathology, Amsterdam Universities Medical Center/VUmc CCA Brain Tumor Center, Amsterdam, the Netherlands (Dr Wesseling); the Department of Pathology, Princess Máxima Center for Pediatric Oncology, and University Medical Center Utrecht, Utrecht, the Netherlands (Dr Wesseling); Division of Neuropathology, The National Hospital for Neurology and Neurosurgery, University College London NHS Foundation Trust, London, United Kingdom (Dr Brandner); the Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, London, United Kingdom (Dr Brandner); the Department of Pathology, Northwestern University Feinberg School of Medicine, Chicago, Illinois (Dr Brat); the Department of Pathology, St. Jude Children's Research Hospital, Memphis, Tennessee (Dr Ellison); the Department of Radiology, Oncology and Anatomic Pathology, University La Sapienza, Rome, Italy (Dr Giangaspero); IRCCS Neuromed, Pozzilli, Isernia, Italy (Dr Giangaspero); the Department of Pathology, University of Louisville School of Medicine, Louisville, Kentucky (Dr Hattab); the Department of Laboratory Medicine & Pathobiology, The Hospital for Sick Children, Toronto, Ontario, Canada (Dr Hawkins); Project Management Office, Royal College of Pathologists of Australasia, Sydney, Australia (Ms Judge); the Departments of Pathology, Neurology, and Neurosurgery, University of Colorado, Aurora (Dr Kleinschmidt-DeMasters); the Department of Laboratory Medicine and Pathology (Neuropathology), Tokyo Metropolitan Neurological Hospital, Tokyo, Japan (Dr Komori); the Department of Pathology, Tokyo Women's Medical University School of Medicine, Tokyo, Japan (Dr Komori); Alfred Anatomical Pathology and NNF, Victorian Brain Bank, Carlton, Victoria, Australia (Dr McLean); Institute of Neuropathology, University Hospital Münster, Münster, Germany (Dr Paulus); Division of Neuropathology, Department of Pathology, University of California, San Francisco (Dr Perry); the Department of Neuropathology, Heinrich Heine University, Düsseldorf, Germany (Dr Reifenberger); German Cancer Consortium (DKTK), Partner Site Essen/Düsseldorf, Düsseldorf, Germany (Dr Reifenberger); the Department of Neurology, University Hospital and University of Zurich, Zurich, Switzerland (Dr Weller); and the Department of Histopathology, Addenbrookes Hospital, Cambridge, United Kingdom (Dr Rous); ICCR Steering Group Representative (Dr Rous).

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http://dx.doi.org/10.5858/arpa.2018-0565-OADOI Listing
June 2019

How we treat glioblastoma.

ESMO Open 2019 17;4(Suppl 2):e000520. Epub 2019 Jun 17.

Department of Neurology & Brain Tumor Center, University Hospital and University of Zürich, Zurich, Switzerland.

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http://dx.doi.org/10.1136/esmoopen-2019-000520DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6586206PMC
June 2019

Laser-Induced Microplasma as an Ambient Ionization Approach for the Mass-Spectrometric Analysis of Liquid Samples.

Anal Chem 2019 May 11;91(9):5922-5928. Epub 2019 Apr 11.

Bundesanstalt für Materialforschung und -prüfung (BAM) , Richard-Willstätter-Straße 11 , 12489 Berlin , Germany.

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http://dx.doi.org/10.1021/acs.analchem.9b00329DOI Listing
May 2019

How we treat patients with leptomeningeal metastases.

ESMO Open 2019 21;4(Suppl 2):e000507. Epub 2019 May 21.

Department of Neurology & Brain Tumor Center, University Hospital and University of Zurich, Zurich, Switzerland.

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http://dx.doi.org/10.1136/esmoopen-2019-000507DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6555600PMC
May 2019

Complementary and alternative medicine use by glioma patients in Switzerland.

Neurooncol Pract 2019 May 12;6(3):237-244. Epub 2018 Oct 12.

Department of Neurology, University Hospital Zurich and University of Zurich, Switzerland.

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http://dx.doi.org/10.1093/nop/npy035DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6656325PMC
May 2019

Evolutionary Trajectories of IDH Glioblastomas Reveal a Common Path of Early Tumorigenesis Instigated Years ahead of Initial Diagnosis.

Cancer Cell 2019 Apr 21;35(4):692-704.e12. Epub 2019 Mar 21.

Division of Molecular Genetics, German Cancer Research Consortium (DKTK), German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120 Heidelberg, Germany; Heidelberg Center for Personalized Oncology, DKFZ-HIPO, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120 Heidelberg, Germany. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S15356108193010
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http://dx.doi.org/10.1016/j.ccell.2019.02.007DOI Listing
April 2019

Use of metformin and outcome of patients with newly diagnosed glioblastoma: Pooled analysis.

Int J Cancer 2019 Apr 13. Epub 2019 Apr 13.

Department of Neurology and Wilhelm Sander-NeuroOncology Unit, Regensburg University Hospital, Regensburg, Germany.

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http://dx.doi.org/10.1002/ijc.32337DOI Listing
April 2019

Efficient Screening of Combinatorial Peptide Libraries by Spatially Ordered Beads Immobilized on Conventional Glass Slides.

High Throughput 2019 Apr 30;8(2). Epub 2019 Apr 30.

Division 1.5 Protein Analysis, Federal Institute for Materials Research and Testing (BAM), Richard-Willstätter-Strasse 11, 12489 Berlin, Germany.

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http://dx.doi.org/10.3390/ht8020011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6631230PMC
April 2019

Unfavorable Structural and Functional Outcomes in Myelin Oligodendrocyte Glycoprotein Antibody-Associated Optic Neuritis.

J Neuroophthalmol 2019 Mar;39(1):3-7

Neuroimmunology and Multiple Sclerosis Research (IJ, JVMH, SL, RM, AL, and SS), Neurology Clinic, University Hospital Zurich, University of Zurich, Zurich, Switzerland; Department of Ophthalmology (JVMH, KPW, and KL), University Hospital Zurich, Zurich, Switzerland; Department of Ophthalmology (MP), Luzerner Kantonsspital, Lucerne, Switzerland; Clinical Department of Neurology (MR), Medical University of Innsbruck, Innsbruck, Austria; and Neurology Clinic (MW, KPW), University Hospital Zurich, University of Zurich, Zurich, Switzerland.

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http://Insights.ovid.com/crossref?an=00041327-900000000-9923
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http://dx.doi.org/10.1097/WNO.0000000000000669DOI Listing
March 2019

Contraceptive drugs mitigate experimental stroke-induced brain injury.

Cardiovasc Res 2019 Mar;115(3):637-646

Department of Neurology, University Hospital and University of Zurich, Frauenklinikstrasse 26, 8091 Zurich, Switzerland.

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https://academic.oup.com/cardiovascres/advance-article/doi/1
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http://dx.doi.org/10.1093/cvr/cvy248DOI Listing
March 2019

Digging into the Sequential Space of Thiolactone Precision Polymers: A Combinatorial Strategy to Identify Functional Domains.

Angew Chem Int Ed Engl 2019 Feb 17;58(7):1960-1964. Epub 2019 Jan 17.

Laboratory for Organic Synthesis of Functional Systems, Department of Chemistry, Humboldt-Universität zu Berlin, Brook-Taylor-Strassse 2, 12489, Berlin, Germany.

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http://dx.doi.org/10.1002/anie.201810393DOI Listing
February 2019

Chemotherapy sensitization of glioblastoma by focused ultrasound-mediated delivery of therapeutic liposomes.

J Control Release 2019 Feb 8;295:130-139. Epub 2018 Dec 8.

Institute of Pharmaceutical Sciences, Department of Chemistry and Applied Biosciences, ETH Zurich, Vladimir-Prelog-Weg 1-5, 8093 Zurich, Switzerland.

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http://dx.doi.org/10.1016/j.jconrel.2018.12.009DOI Listing
February 2019

Closed-loop cavitation control for focused ultrasound-mediated blood-brain barrier opening by long-circulating microbubbles.

Phys Med Biol 2019 02 11;64(4):045012. Epub 2019 Feb 11.

Center for MR-Research, University Children's Hospital Zurich, 8032 Zurich, Switzerland. Institute for Biomedical Engineering, ETH Zurich, 8091 Zurich, Switzerland. Information Technology and Electrical Engineering Department, Swiss Federal Institute of Technology, Institute for Biomedical Engineering, ETH Zurich, ETZ F 64.1, Gloriastrasse 35, 8092, Zurich, Switzerland. Author to whom any correspondence should be addressed.

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http://dx.doi.org/10.1088/1361-6560/aafaa5DOI Listing
February 2019

Pseudoprogression: fact or wishful thinking in neuro-oncology?

Lancet Oncol 2018 12;19(12):1561-1563

Department of Neurology & Brain Tumor Center, University Hospital Zurich, CH-8091 Zurich, Switzerland.

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http://dx.doi.org/10.1016/S1470-2045(18)30654-5DOI Listing
December 2018

Epidermal growth factor receptor and ligand family expression and activity in glioblastoma.

J Neurochem 2018 10 16;147(1):99-109. Epub 2018 Aug 16.

Laboratory of Molecular Neuro-Oncology, Department of Neurology, University Hospital and University of Zurich, Zurich, Switzerland.

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http://dx.doi.org/10.1111/jnc.14538DOI Listing
October 2018

Associations of anticoagulant use with outcome in newly diagnosed glioblastoma.

Eur J Cancer 2018 09 20;101:95-104. Epub 2018 Jul 20.

Department of Neurology & Brain Tumor Center, University Hospital and University of Zurich, Zurich, Switzerland.

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http://dx.doi.org/10.1016/j.ejca.2018.06.029DOI Listing
September 2018

Bevacizumab and temozolomide in patients with first recurrence of WHO grade II and III glioma, without 1p/19q co-deletion (TAVAREC): a randomised controlled phase 2 EORTC trial.

Lancet Oncol 2018 09 13;19(9):1170-1179. Epub 2018 Aug 13.

The Brain and Spine Institute (ICM), Sorbonne Université, The National Institute of Health and Medical Research (INSERM), National Centre for Scientific Research (CNRS), Public Assistance-Paris Hospitals (AP-HP), Hôpital Pitié-Salpêtrière, Paris, France.

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https://linkinghub.elsevier.com/retrieve/pii/S14702045183036
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http://dx.doi.org/10.1016/S1470-2045(18)30362-0DOI Listing
September 2018

Investigations of the Copper Peptide Hepcidin-25 by LC-MS/MS and NMR.

Int J Mol Sci 2018 Aug 2;19(8). Epub 2018 Aug 2.

Federal Institute for Materials Research and Testing (BAM), Division 1.5 Protein Analysis, Richard-Willstätter-Strasse 11, 12489 Berlin, Germany.

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http://www.mdpi.com/1422-0067/19/8/2271
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http://dx.doi.org/10.3390/ijms19082271DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6121404PMC
August 2018

Current state of immunotherapy for glioblastoma.

Nat Rev Clin Oncol 2018 07;15(7):422-442

Department of Neurology, University Hospital and University of Zurich, Zurich, Switzerland.

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http://www.nature.com/articles/s41571-018-0003-5
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http://dx.doi.org/10.1038/s41571-018-0003-5DOI Listing
July 2018

Epidermal Growth Factor Receptor Extracellular Domain Mutations in Glioblastoma Present Opportunities for Clinical Imaging and Therapeutic Development.

Cancer Cell 2018 07;34(1):163-177.e7

Department of Neurosurgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA; Center for Biomedical Image Computing and Analytics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA; Abramson Cancer Center, University of Pennsylvania, Philadelphia, PA 19104, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2018.06.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6424337PMC
July 2018

Glioblastoma quo vadis: Will migration and invasiveness reemerge as therapeutic targets?

Cancer Treat Rev 2018 Jul 26;68:145-154. Epub 2018 Jun 26.

Department of Neurology, University Hospital & University of Zurich, Frauenklinikstrasse 26, CH-8091 Zurich, Switzerland.

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http://dx.doi.org/10.1016/j.ctrv.2018.06.017DOI Listing
July 2018

The natural HLA ligandome of glioblastoma stem-like cells: antigen discovery for T cell-based immunotherapy.

Acta Neuropathol 2018 06 20;135(6):923-938. Epub 2018 Mar 20.

Laboratory of Molecular Neuro-Oncology, Department of Neurology, Clinical Neuroscience Center, University Hospital Zurich and University of Zurich, Frauenklinikstrasse 26, 8091, Zurich, Switzerland.

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http://dx.doi.org/10.1007/s00401-018-1836-9DOI Listing
June 2018

Next generation neuro-oncology.

Authors:
Michael Weller

Eur J Cancer 2018 06 12;96:1-5. Epub 2018 Apr 12.

Department of Neurology, University Hospital and University of Zurich, Frauenklinikstrasse 26, CH-8091 Zürich, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.ejca.2018.03.016DOI Listing
June 2018

Improved LC-MS/MS method for the quantification of hepcidin-25 in clinical samples.

Anal Bioanal Chem 2018 Jun 18;410(16):3835-3846. Epub 2018 Apr 18.

Division 1.5 Protein Analysis, Federal Institute for Materials Research and Testing (BAM), Richard-Willstätter-Strasse 11, 12489, Berlin, Germany.

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http://dx.doi.org/10.1007/s00216-018-1056-0DOI Listing
June 2018

Diagnostic value of F-fluordesoxyglucose positron emission tomography for patients with brain metastasis from unknown primary site.

Eur J Cancer 2018 06 17;96:64-72. Epub 2018 Apr 17.

Department of Neurology and Brain Tumor Center, University Hospital and University of Zurich, Frauenklinikstrasse 26, CH-8091, Zurich, Switzerland; Neuro-oncology, Department of Neurosurgery, University Hospital Lille, Salengro Hospital, Rue Emile Laine, FR-59037, Lille, France; Neurology, Department of Medical Oncology, Oscar Lambret Center, FR-59020, Lille, France; Inserm U-1192, Villeneuve d'Ascq, France.

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http://dx.doi.org/10.1016/j.ejca.2018.03.010DOI Listing
June 2018

Do statins, ACE inhibitors or sartans improve outcome in primary glioblastoma?

J Neurooncol 2018 May 8;138(1):163-171. Epub 2018 Feb 8.

Department of Neurology, University Hospital and University of Zurich, Zurich, Switzerland.

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http://link.springer.com/10.1007/s11060-018-2786-8
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http://dx.doi.org/10.1007/s11060-018-2786-8DOI Listing
May 2018

Antitumor Activity of DLX1008, an Anti-VEGFA Antibody Fragment with Low Picomolar Affinity, in Human Glioma Models.

J Pharmacol Exp Ther 2018 05 5;365(2):422-429. Epub 2018 Mar 5.

Laboratory of Molecular Neuro-Oncology, Department of Neurology, University Hospital and University of Zurich (E.S., M.W.), and Cell Medica Switzerland AG, Schlieren (D.J.P., M.D., A.M., T.K., A.S.), Zurich, Switzerland.

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http://dx.doi.org/10.1124/jpet.117.246249DOI Listing
May 2018

Where does O -methylguanine DNA methyltransferase promoter methylation assessment place temozolomide in the future standards of care for glioblastoma?

Authors:
Michael Weller

Cancer 2018 04 30;124(7):1316-1318. Epub 2018 Jan 30.

Department of Neurology, University Hospital and University of Zurich, Zurich, Switzerland.

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http://doi.wiley.com/10.1002/cncr.31244
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http://dx.doi.org/10.1002/cncr.31244DOI Listing
April 2018

Online immunocapture ICP-MS for the determination of the metalloprotein ceruloplasmin in human serum.

BMC Res Notes 2018 Apr 2;11(1):213. Epub 2018 Apr 2.

Division 1.5 Protein Analysis, Federal Institute for Materials Research and Testing (BAM), Richard-Willstätter-Strasse 11, 12489, Berlin, Germany.

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http://dx.doi.org/10.1186/s13104-018-3324-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5879926PMC
April 2018

Transcriptional control of O -methylguanine DNA methyltransferase expression and temozolomide resistance in glioblastoma.

J Neurochem 2018 03;144(6):780-790

Department of Neurology, Laboratory of Molecular Neuro-Oncology, University Hospital and University of Zurich, Zurich, Switzerland.

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http://doi.wiley.com/10.1111/jnc.14326
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March 2018

Working plan for the use of patient-reported outcome measures in adults with brain tumours: a Response Assessment in Neuro-Oncology (RANO) initiative.

Lancet Oncol 2018 03;19(3):e173-e180

Department of Neurology, Leiden University Medical Center, Leiden, Netherlands; Department of Neurology, Haaglanden Medical Center, The Hague, Netherlands. Electronic address:

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March 2018

DNA methylation-based classification of central nervous system tumours.

Authors:
David Capper David T W Jones Martin Sill Volker Hovestadt Daniel Schrimpf Dominik Sturm Christian Koelsche Felix Sahm Lukas Chavez David E Reuss Annekathrin Kratz Annika K Wefers Kristin Huang Kristian W Pajtler Leonille Schweizer Damian Stichel Adriana Olar Nils W Engel Kerstin Lindenberg Patrick N Harter Anne K Braczynski Karl H Plate Hildegard Dohmen Boyan K Garvalov Roland Coras Annett Hölsken Ekkehard Hewer Melanie Bewerunge-Hudler Matthias Schick Roger Fischer Rudi Beschorner Jens Schittenhelm Ori Staszewski Khalida Wani Pascale Varlet Melanie Pages Petra Temming Dietmar Lohmann Florian Selt Hendrik Witt Till Milde Olaf Witt Eleonora Aronica Felice Giangaspero Elisabeth Rushing Wolfram Scheurlen Christoph Geisenberger Fausto J Rodriguez Albert Becker Matthias Preusser Christine Haberler Rolf Bjerkvig Jane Cryan Michael Farrell Martina Deckert Jürgen Hench Stephan Frank Jonathan Serrano Kasthuri Kannan Aristotelis Tsirigos Wolfgang Brück Silvia Hofer Stefanie Brehmer Marcel Seiz-Rosenhagen Daniel Hänggi Volkmar Hans Stephanie Rozsnoki Jordan R Hansford Patricia Kohlhof Bjarne W Kristensen Matt Lechner Beatriz Lopes Christian Mawrin Ralf Ketter Andreas Kulozik Ziad Khatib Frank Heppner Arend Koch Anne Jouvet Catherine Keohane Helmut Mühleisen Wolf Mueller Ute Pohl Marco Prinz Axel Benner Marc Zapatka Nicholas G Gottardo Pablo Hernáiz Driever Christof M Kramm Hermann L Müller Stefan Rutkowski Katja von Hoff Michael C Frühwald Astrid Gnekow Gudrun Fleischhack Stephan Tippelt Gabriele Calaminus Camelia-Maria Monoranu Arie Perry Chris Jones Thomas S Jacques Bernhard Radlwimmer Marco Gessi Torsten Pietsch Johannes Schramm Gabriele Schackert Manfred Westphal Guido Reifenberger Pieter Wesseling Michael Weller Vincent Peter Collins Ingmar Blümcke Martin Bendszus Jürgen Debus Annie Huang Nada Jabado Paul A Northcott Werner Paulus Amar Gajjar Giles W Robinson Michael D Taylor Zane Jaunmuktane Marina Ryzhova Michael Platten Andreas Unterberg Wolfgang Wick Matthias A Karajannis Michel Mittelbronn Till Acker Christian Hartmann Kenneth Aldape Ulrich Schüller Rolf Buslei Peter Lichter Marcel Kool Christel Herold-Mende David W Ellison Martin Hasselblatt Matija Snuderl Sebastian Brandner Andrey Korshunov Andreas von Deimling Stefan M Pfister

Nature 2018 03 14;555(7697):469-474. Epub 2018 Mar 14.

Hopp Children's Cancer Center at the NCT Heidelberg (KiTZ), Heidelberg, Germany.

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March 2018

Ten Basic Rules of Antibody Validation.

Authors:
Michael G Weller

Anal Chem Insights 2018 8;13:1177390118757462. Epub 2018 Feb 8.

Division 1.5 Protein Analysis, Federal Institute for Materials Research and Testing (BAM), Berlin, Germany.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5813849PMC
February 2018

Negative control of the HGF/c-MET pathway by TGF-β: a new look at the regulation of stemness in glioblastoma.

Cell Death Dis 2017 12 13;8(12):3210. Epub 2017 Dec 13.

Laboratory of Molecular Neuro-Oncology, Department of Neurology, University Hospital and University of Zurich, Zurich, 8091, Switzerland.

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http://www.nature.com/articles/s41419-017-0051-2
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870582PMC
December 2017