Publications by authors named "Michael V Holmes"

100Publications

Genomic and drug target evaluation of 90 cardiovascular proteins in 30,931 individuals.

Nat Metab 2020 Oct 16;2(10):1135-1148. Epub 2020 Oct 16.

Department of Medicine, Karolinska Institute, Solna, Sweden.

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http://dx.doi.org/10.1038/s42255-020-00287-2DOI Listing
October 2020

Genetic variants mimicking therapeutic inhibition of IL-6 receptor signaling and risk of COVID-19.

Lancet Rheumatol 2020 Nov 25;2(11):e658-e659. Epub 2020 Sep 25.

Medical Research Council Population Health Research Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK.

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http://dx.doi.org/10.1016/S2665-9913(20)30345-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7518829PMC
November 2020

Observational and Genetic Associations of Body Mass Index and Hepatobiliary Diseases in a Relatively Lean Chinese Population.

JAMA Netw Open 2020 Oct 1;3(10):e2018721. Epub 2020 Oct 1.

Clinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Department of Population Health, Big Data Institute University of Oxford, Oxford, United Kingdom.

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http://dx.doi.org/10.1001/jamanetworkopen.2020.18721DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7532388PMC
October 2020

Response by Siedlinski et al to Letters Regarding Article, "White Blood Cells and Blood Pressure: A Mendelian Randomization Study".

Circulation 2020 Sep 28;142(13):e191-e192. Epub 2020 Sep 28.

Department of Internal and Agricultural Medicine, Faculty of Medicine, Jagiellonian University Medical College, Krakow, Poland (M.S., T.J.G.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.120.049870DOI Listing
September 2020

The relationship between body mass index and the risk of development of Dupuytren's disease: a Mendelian randomization study.

J Hand Surg Eur Vol 2020 Sep 25:1753193420958553. Epub 2020 Sep 25.

Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK.

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http://dx.doi.org/10.1177/1753193420958553DOI Listing
September 2020

Genome-wide Study Identifies Association between HLA-B55:01 and Self-Reported Penicillin Allergy.

Am J Hum Genet 2020 Oct 3;107(4):612-621. Epub 2020 Sep 3.

Department of Epidemiology Research, Statens Serum Institut, Copenhagen 2300, Denmark; Department of Clinical Sciences, Lund University Diabetes Centre, 214 28 Malmö, Sweden; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki 00014, Finland.

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http://dx.doi.org/10.1016/j.ajhg.2020.08.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7536643PMC
October 2020

Association of physical activity with risk of hepatobiliary diseases in China: a prospective cohort study of 0.5 million people.

Br J Sports Med 2020 Aug 21. Epub 2020 Aug 21.

Department of Epidemiology and Biostatistics, School of Public Health, Peking University Health Science Center, Beijing, China

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http://dx.doi.org/10.1136/bjsports-2020-102174DOI Listing
August 2020

Association of Factor V Leiden With Subsequent Atherothrombotic Events: A GENIUS-CHD Study of Individual Participant Data.

Circulation 2020 Aug 13;142(6):546-555. Epub 2020 Jul 13.

Institute of Cardiovascular Science and UCL BHF Research Accelerator, Faculty of Population Health Science, University College London, United Kingdom (A.F.S., L.J.H., K.D., J.D., A.D.H., F.W.A., R.S.P.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.119.045526DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7493828PMC
August 2020

Mendel's laws, Mendelian randomization and causal inference in observational data: substantive and nomenclatural issues.

Eur J Epidemiol 2020 Feb 23;35(2):99-111. Epub 2020 Mar 23.

London School of Hygiene and Tropical Medicine, London, UK.

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http://dx.doi.org/10.1007/s10654-020-00622-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7125255PMC
February 2020

White Blood Cells and Blood Pressure: A Mendelian Randomization Study.

Circulation 2020 Apr 9;141(16):1307-1317. Epub 2020 Mar 9.

Department of Internal and Agricultural Medicine, Faculty of Medicine, Jagiellonian University Medical College, Krakow, Poland (M.S., E.J., T.J.G.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.119.045102DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7176352PMC
April 2020

Apolipoprotein A-I concentrations and risk of coronary artery disease: A Mendelian randomization study.

Atherosclerosis 2020 04 14;299:56-63. Epub 2020 Feb 14.

Computational Medicine, Faculty of Medicine, University of Oulu, Oulu, Finland; Center for Life Course Health Research, Faculty of Medicine, University of Oulu, Oulu, Finland; Biocenter Oulu, University of Oulu, Oulu, Finland; National Institute for Health and Welfare, Helsinki, Finland. Electronic address:

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http://dx.doi.org/10.1016/j.atherosclerosis.2020.02.002DOI Listing
April 2020

Using human genetics to guide the repurposing of medicines.

Int J Epidemiol 2020 Feb 25. Epub 2020 Feb 25.

Big Data Institute at the Li Ka Shing Centre for Health Information and Discovery, University of Oxford, Oxford, UK.

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http://dx.doi.org/10.1093/ije/dyaa015DOI Listing
February 2020

Socioeconomic Status in Relation to Risks of Major Gastrointestinal Cancers in Chinese Adults: A Prospective Study of 0.5 Million People.

Cancer Epidemiol Biomarkers Prev 2020 Apr 27;29(4):823-831. Epub 2020 Jan 27.

Clinical Trial Service Unit & Epidemiological Studies Unit (CTSU), Nuffield Department of Population Health, University of Oxford, Oxford, United Kingdom.

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http://dx.doi.org/10.1158/1055-9965.EPI-19-0585DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7242093PMC
April 2020

Genome-wide association and Mendelian randomisation analysis provide insights into the pathogenesis of heart failure.

Authors:
Sonia Shah Albert Henry Carolina Roselli Honghuang Lin Garðar Sveinbjörnsson Ghazaleh Fatemifar Åsa K Hedman Jemma B Wilk Michael P Morley Mark D Chaffin Anna Helgadottir Niek Verweij Abbas Dehghan Peter Almgren Charlotte Andersson Krishna G Aragam Johan Ärnlöv Joshua D Backman Mary L Biggs Heather L Bloom Jeffrey Brandimarto Michael R Brown Leonard Buckbinder David J Carey Daniel I Chasman Xing Chen Xu Chen Jonathan Chung William Chutkow James P Cook Graciela E Delgado Spiros Denaxas Alexander S Doney Marcus Dörr Samuel C Dudley Michael E Dunn Gunnar Engström Tõnu Esko Stephan B Felix Chris Finan Ian Ford Mohsen Ghanbari Sahar Ghasemi Vilmantas Giedraitis Franco Giulianini John S Gottdiener Stefan Gross Daníel F Guðbjartsson Rebecca Gutmann Christopher M Haggerty Pim van der Harst Craig L Hyde Erik Ingelsson J Wouter Jukema Maryam Kavousi Kay-Tee Khaw Marcus E Kleber Lars Køber Andrea Koekemoer Claudia Langenberg Lars Lind Cecilia M Lindgren Barry London Luca A Lotta Ruth C Lovering Jian'an Luan Patrik Magnusson Anubha Mahajan Kenneth B Margulies Winfried März Olle Melander Ify R Mordi Thomas Morgan Andrew D Morris Andrew P Morris Alanna C Morrison Michael W Nagle Christopher P Nelson Alexander Niessner Teemu Niiranen Michelle L O'Donoghue Anjali T Owens Colin N A Palmer Helen M Parry Markus Perola Eliana Portilla-Fernandez Bruce M Psaty Kenneth M Rice Paul M Ridker Simon P R Romaine Jerome I Rotter Perttu Salo Veikko Salomaa Jessica van Setten Alaa A Shalaby Diane T Smelser Nicholas L Smith Steen Stender David J Stott Per Svensson Mari-Liis Tammesoo Kent D Taylor Maris Teder-Laving Alexander Teumer Guðmundur Thorgeirsson Unnur Thorsteinsdottir Christian Torp-Pedersen Stella Trompet Benoit Tyl Andre G Uitterlinden Abirami Veluchamy Uwe Völker Adriaan A Voors Xiaosong Wang Nicholas J Wareham Dawn Waterworth Peter E Weeke Raul Weiss Kerri L Wiggins Heming Xing Laura M Yerges-Armstrong Bing Yu Faiez Zannad Jing Hua Zhao Harry Hemingway Nilesh J Samani John J V McMurray Jian Yang Peter M Visscher Christopher Newton-Cheh Anders Malarstig Hilma Holm Steven A Lubitz Naveed Sattar Michael V Holmes Thomas P Cappola Folkert W Asselbergs Aroon D Hingorani Karoline Kuchenbaecker Patrick T Ellinor Chim C Lang Kari Stefansson J Gustav Smith Ramachandran S Vasan Daniel I Swerdlow R Thomas Lumbers

Nat Commun 2020 01 9;11(1):163. Epub 2020 Jan 9.

British Heart Foundation Research Accelerator, University College London, London, UK.

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http://dx.doi.org/10.1038/s41467-019-13690-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6952380PMC
January 2020

Polygenic risk scores and the prediction of common diseases.

Int J Epidemiol 2020 02;49(1):1-3

Medical Research Council Population Health Research Unit, University of Oxford, Oxford, UK.

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http://dx.doi.org/10.1093/ije/dyz254DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7261205PMC
February 2020

Phenome-wide association analysis of LDL-cholesterol lowering genetic variants in PCSK9.

Authors:
Amand F Schmidt Michael V Holmes David Preiss Daniel I Swerdlow Spiros Denaxas Ghazaleh Fatemifar Rupert Faraway Chris Finan Dennis Valentine Zammy Fairhurst-Hunter Fernando Pires Hartwig Bernardo Lessa Horta Elina Hypponen Christine Power Max Moldovan Erik van Iperen Kees Hovingh Ilja Demuth Kristina Norman Elisabeth Steinhagen-Thiessen Juri Demuth Lars Bertram Christina M Lill Stefan Coassin Johann Willeit Stefan Kiechl Karin Willeit Dan Mason John Wright Richard Morris Goya Wanamethee Peter Whincup Yoav Ben-Shlomo Stela McLachlan Jackie F Price Mika Kivimaki Catherine Welch Adelaida Sanchez-Galvez Pedro Marques-Vidal Andrew Nicolaides Andrie G Panayiotou N Charlotte Onland-Moret Yvonne T van der Schouw Giuseppe Matullo Giovanni Fiorito Simonetta Guarrera Carlotta Sacerdote Nicholas J Wareham Claudia Langenberg Robert A Scott Jian'an Luan Martin Bobak Sofia Malyutina Andrzej Pająk Ruzena Kubinova Abdonas Tamosiunas Hynek Pikhart Niels Grarup Oluf Pedersen Torben Hansen Allan Linneberg Tine Jess Jackie Cooper Steve E Humphries Murray Brilliant Terrie Kitchner Hakon Hakonarson David S Carrell Catherine A McCarty Kirchner H Lester Eric B Larson David R Crosslin Mariza de Andrade Dan M Roden Joshua C Denny Cara Carty Stephen Hancock John Attia Elizabeth Holliday Rodney Scott Peter Schofield Martin O'Donnell Salim Yusuf Michael Chong Guillaume Pare Pim van der Harst M Abdullah Said Ruben N Eppinga Niek Verweij Harold Snieder Tim Christen D O Mook-Kanamori Stefan Gustafsson Lars Lind Erik Ingelsson Raha Pazoki Oscar Franco Albert Hofman Andre Uitterlinden Abbas Dehghan Alexander Teumer Sebastian Baumeister Marcus Dörr Markus M Lerch Uwe Völker Henry Völzke Joey Ward Jill P Pell Tom Meade Ingrid E Christophersen Anke H Maitland-van der Zee Ekaterina V Baranova Robin Young Ian Ford Archie Campbell Sandosh Padmanabhan Michiel L Bots Diederick E Grobbee Philippe Froguel Dorothée Thuillier Ronan Roussel Amélie Bonnefond Bertrand Cariou Melissa Smart Yanchun Bao Meena Kumari Anubha Mahajan Jemma C Hopewell Sudha Seshadri Caroline Dale Rui Providencia E Costa Paul M Ridker Daniel I Chasman Alex P Reiner Marylyn D Ritchie Leslie A Lange Alex J Cornish Sara E Dobbins Kari Hemminki Ben Kinnersley Marc Sanson Karim Labreche Matthias Simon Melissa Bondy Philip Law Helen Speedy James Allan Ni Li Molly Went Niels Weinhold Gareth Morgan Pieter Sonneveld Björn Nilsson Hartmut Goldschmidt Amit Sud Andreas Engert Markus Hansson Harry Hemingway Folkert W Asselbergs Riyaz S Patel Brendan J Keating Naveed Sattar Richard Houlston Juan P Casas Aroon D Hingorani

BMC Cardiovasc Disord 2019 10 29;19(1):240. Epub 2019 Oct 29.

Institute of Cardiovascular Science, University College London, 222 Euston Road, London, NW1 2DA, UK.

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http://dx.doi.org/10.1186/s12872-019-1187-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6820948PMC
October 2019

Causal relationships between obesity and the leading causes of death in women and men.

PLoS Genet 2019 10 24;15(10):e1008405. Epub 2019 Oct 24.

Big Data Institute at the Li Ka Shing Centre for Health Information and Discovery, University of Oxford, Oxford, United Kingdom.

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http://dx.doi.org/10.1371/journal.pgen.1008405DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6812754PMC
October 2019

Physical Activity, Sedentary Leisure Time, Circulating Metabolic Markers, and Risk of Major Vascular Diseases.

Circ Genom Precis Med 2019 09 28;12(9):386-396. Epub 2019 Aug 28.

Clinical Trial Service Unit and Epidemiological Studies Unit (Y.P., C.K., H.D., I.Y.M., Y.C., L.Y., R.W., F.B., R.P., R. Clarke, R. Collins, D.A.B., L.L., M.V.H., Z.C.), Nuffield Department of Population Health, University of Oxford, United Kingdom.

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http://dx.doi.org/10.1161/CIRCGEN.118.002527DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6752700PMC
September 2019

Commentary: Mendelian randomization and women's health.

Int J Epidemiol 2019 06;48(3):830-833

Big Data Institute at the Li Ka Shing Centre for Health Information and Discovery, University of Oxford, Oxford, UK.

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http://dx.doi.org/10.1093/ije/dyz141DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6659371PMC
June 2019

Variability in aspirin efficacy: all in the genes?

Eur Heart J 2019 11;40(41):3393-3396

MRC Population Health Research Unit, Nuffield Department of Population Health, Oxford, UK.

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https://academic.oup.com/eurheartj/advance-article/doi/10.10
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http://dx.doi.org/10.1093/eurheartj/ehz456DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6823614PMC
November 2019

Direct Estimation of HDL-Mediated Cholesterol Efflux Capacity from Serum.

Clin Chem 2019 08 17;65(8):1042-1050. Epub 2019 Apr 17.

Computational Medicine, Faculty of Medicine, University of Oulu and Biocenter Oulu, Oulu, Finland;

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http://www.clinchem.org/lookup/doi/10.1373/clinchem.2018.299
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http://dx.doi.org/10.1373/clinchem.2018.299222DOI Listing
August 2019

Association of Chromosome 9p21 With Subsequent Coronary Heart Disease Events.

Authors:
Riyaz S Patel Amand F Schmidt Vinicius Tragante Raymond O McCubrey Michael V Holmes Laurence J Howe Kenan Direk Axel Åkerblom Karin Leander Salim S Virani Karol A Kaminski Jochen D Muehlschlegel Marie-Pierre Dubé Hooman Allayee Peter Almgren Maris Alver Ekaterina V Baranova Hassan Behlouli Bram Boeckx Peter S Braund Lutz P Breitling Graciela Delgado Nubia E Duarte Line Dufresne Niclas Eriksson Luisa Foco Crystel M Gijsberts Yan Gong Jaana Hartiala Mahyar Heydarpour Jaroslav A Hubacek Marcus Kleber Daniel Kofink Pekka Kuukasjärvi Vei-Vei Lee Andreas Leiherer Petra A Lenzini Daniel Levin Leo-Pekka Lyytikäinen Nicola Martinelli Ute Mons Christopher P Nelson Kjell Nikus Anna P Pilbrow Rafal Ploski Yan V Sun Michael W T Tanck W H Wilson Tang Stella Trompet Sander W van der Laan Jessica van Setten Ragnar O Vilmundarson Chiara Viviani Anselmi Efthymia Vlachopoulou Eric Boerwinkle Carlo Briguori John F Carlquist Kathryn F Carruthers Gavino Casu John Deanfield Panos Deloukas Frank Dudbridge Natalie Fitzpatrick Bruna Gigante Stefan James Marja-Liisa Lokki Paulo A Lotufo Nicola Marziliano Ify R Mordi Joseph B Muhlestein Chris Newton Cheh Jan Pitha Christoph H Saely Ayman Samman-Tahhan Pratik B Sandesara Andrej Teren Adam Timmis Frans Van de Werf Els Wauters Arthur A M Wilde Ian Ford David J Stott Ale Algra Maria G Andreassi Diego Ardissino Benoit J Arsenault Christie M Ballantyne Thomas O Bergmeijer Connie R Bezzina Simon C Body Peter Bogaty Gert J de Borst Hermann Brenner Ralph Burkhardt Clara Carpeggiani Gianluigi Condorelli Rhonda M Cooper-DeHoff Sharon Cresci Ulf de Faire Robert N Doughty Heinz Drexel James C Engert Keith A A Fox Domenico Girelli Emil Hagström Stanley L Hazen Claes Held Harry Hemingway Imo E Hoefer G Kees Hovingh Julie A Johnson Pim A de Jong J Wouter Jukema Marcin P Kaczor Mika Kähönen Jiri Kettner Marek Kiliszek Olaf H Klungel Bo Lagerqvist Diether Lambrechts Jari O Laurikka Terho Lehtimäki Daniel Lindholm Bakhtawar K Mahmoodi Anke H Maitland-van der Zee Ruth McPherson Olle Melander Andres Metspalu Witold Pepinski Oliviero Olivieri Grzegorz Opolski Colin N Palmer Gerard Pasterkamp Carl J Pepine Alexandre C Pereira Louise Pilote Arshed A Quyyumi A Mark Richards Marek Sanak Markus Scholz Agneta Siegbahn Juha Sinisalo J Gustav Smith John A Spertus Alexandre F R Stewart Wojciech Szczeklik Anna Szpakowicz Jurriën M Ten Berg George Thanassoulis Joachim Thiery Yolanda van der Graaf Frank L J Visseren Johannes Waltenberger Pim Van der Harst Jean-Claude Tardif Naveed Sattar Chim C Lang Guillaume Pare James M Brophy Jeffrey L Anderson Winfried März Lars Wallentin Vicky A Cameron Benjamin D Horne Nilesh J Samani Aroon D Hingorani Folkert W Asselbergs

Circ Genom Precis Med 2019 04 21;12(4):e002471. Epub 2019 Mar 21.

Institute of Cardiovascular Science, Faculty of Population Health Science (R.S.P., A.F.S., L.J.H., K.D., J.D., A.D.H., F.W.A.).

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http://dx.doi.org/10.1161/CIRCGEN.119.002471DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6625876PMC
April 2019

Subsequent Event Risk in Individuals With Established Coronary Heart Disease.

Authors:
Riyaz S Patel Vinicius Tragante Amand F Schmidt Raymond O McCubrey Michael V Holmes Laurence J Howe Kenan Direk Axel Åkerblom Karin Leander Salim S Virani Karol A Kaminski Jochen D Muehlschlegel Hooman Allayee Peter Almgren Maris Alver Ekaterina V Baranova Hassan Behloui Bram Boeckx Peter S Braund Lutz P Breitling Graciela Delgado Nubia E Duarte Marie-Pierre Dubé Line Dufresne Niclas Eriksson Luisa Foco Markus Scholz Crystel M Gijsberts Charlotte Glinge Yan Gong Jaana Hartiala Mahyar Heydarpour Jaroslav A Hubacek Marcus Kleber Daniel Kofink Salma Kotti Pekka Kuukasjärvi Vei-Vei Lee Andreas Leiherer Petra A Lenzini Daniel Levin Leo-Pekka Lyytikäinen Nicola Martinelli Ute Mons Christopher P Nelson Kjell Nikus Anna P Pilbrow Rafal Ploski Yan V Sun Michael W T Tanck W H Wilson Tang Stella Trompet Sander W van der Laan Jessica Van Setten Ragnar O Vilmundarson Chiara Viviani Anselmi Efthymia Vlachopoulou Lawien Al Ali Eric Boerwinkle Carlo Briguori John F Carlquist Kathryn F Carruthers Gavino Casu John Deanfield Panos Deloukas Frank Dudbridge Thomas Engstrøm Natalie Fitzpatrick Kim Fox Bruna Gigante Stefan James Marja-Liisa Lokki Paulo A Lotufo Nicola Marziliano Ify R Mordi Joseph B Muhlestein Christopher Newton-Cheh Jan Pitha Christoph H Saely Ayman Samman-Tahhan Pratik B Sandesara Andrej Teren Adam Timmis Frans Van de Werf Els Wauters Arthur A M Wilde Ian Ford David J Stott Ale Algra Maria G Andreassi Diego Ardissino Benoit J Arsenault Christie M Ballantyne Thomas O Bergmeijer Connie R Bezzina Simon C Body Eric H Boersma Peter Bogaty Michiel L Bots Hermann Brenner Jasper J Brugts Ralph Burkhardt Clara Carpeggiani Gianluigi Condorelli Rhonda M Cooper-DeHoff Sharon Cresci Nicolas Danchin Ulf de Faire Robert N Doughty Heinz Drexel James C Engert Keith A A Fox Domenico Girelli Diederick E Grobbee Emil Hagström Stanley L Hazen Claes Held Harry Hemingway Imo E Hoefer G Kees Hovingh Reza Jabbari Julie A Johnson J Wouter Jukema Marcin P Kaczor Mika Kähönen Jiri Kettner Marek Kiliszek Olaf H Klungel Bo Lagerqvist Diether Lambrechts Jari O Laurikka Terho Lehtimäki Daniel Lindholm B K Mahmoodi Anke H Maitland-van der Zee Ruth McPherson Olle Melander Andres Metspalu Anna Niemcunowicz-Janica Oliviero Olivieri Grzegorz Opolski Colin N Palmer Gerard Pasterkamp Carl J Pepine Alexandre C Pereira Louise Pilote Arshed A Quyyumi A Mark Richards Marek Sanak Agneta Siegbahn Tabassome Simon Juha Sinisalo J Gustav Smith John A Spertus Steen Stender Alexandre F R Stewart Wojciech Szczeklik Anna Szpakowicz Jean-Claude Tardif Jurriën M Ten Berg Jacob Tfelt-Hansen George Thanassoulis Joachim Thiery Christian Torp-Pedersen Yolanda van der Graaf Frank L J Visseren Johannes Waltenberger Peter E Weeke Pim Van der Harst Chim C Lang Naveed Sattar Vicky A Cameron Jeffrey L Anderson James M Brophy Guillaume Pare Benjamin D Horne Winfried März Lars Wallentin Nilesh J Samani Aroon D Hingorani Folkert W Asselbergs

Circ Genom Precis Med 2019 04 21;12(4):e002470. Epub 2019 Mar 21.

Institute of Health Informatics (N.F., A. Timmis, H.H., F.W.A.), Faculty of Population Health Science, University College London, United Kingdom.

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http://dx.doi.org/10.1161/CIRCGEN.119.002470DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6629546PMC
April 2019

Human Genetics and Drug Development.

Authors:
Michael V Holmes

N Engl J Med 2019 03;380(11):1076-1079

From the Medical Research Council Population Health Research Unit and the Clinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford, United Kingdom.

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http://dx.doi.org/10.1056/NEJMe1901565DOI Listing
March 2019

Meta-analysis and Mendelian randomization: A review.

Res Synth Methods 2019 Dec 23;10(4):486-496. Epub 2019 Apr 23.

Medical Research Council Integrative Epidemiology Unit, University of Bristol, Bristol, UK.

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http://dx.doi.org/10.1002/jrsm.1346DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6973275PMC
December 2019

A genome-wide association analysis identifies 16 novel susceptibility loci for carpal tunnel syndrome.

Nat Commun 2019 03 4;10(1):1030. Epub 2019 Mar 4.

Nuffield Department of Orthopaedics, Rheumatology, and Musculoskeletal Science, University of Oxford, Botnar Research Centre, Windmill Road, Oxford, OX3 7LD, UK.

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http://dx.doi.org/10.1038/s41467-019-08993-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6399342PMC
March 2019

Cholesteryl Ester Transfer Protein Inhibition for Preventing Cardiovascular Events: JACC Review Topic of the Week.

J Am Coll Cardiol 2019 02;73(4):477-487

Medical Research Council Population Health Research Unit, Clinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford, United Kingdom.

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http://dx.doi.org/10.1016/j.jacc.2018.10.072DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6354546PMC
February 2019

What is 'LDL cholesterol'?

Nat Rev Cardiol 2019 04;16(4):197-198

Medical Research Council Integrative Epidemiology Unit at the University of Bristol, Bristol, UK.

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http://dx.doi.org/10.1038/s41569-019-0157-6DOI Listing
April 2019

Can Mendelian Randomization Shift into Reverse Gear?

Clin Chem 2019 03 28;65(3):363-366. Epub 2019 Jan 28.

Medical Research Council Integrative Epidemiology Unit, University of Bristol, UK.

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http://dx.doi.org/10.1373/clinchem.2018.296806DOI Listing
March 2019

Central adiposity in relation to risk of liver cancer in Chinese adults: A prospective study of 0.5 million people.

Int J Cancer 2019 09 13;145(5):1245-1253. Epub 2019 Feb 13.

Clinical Trial Service Unit and Epidemiological Studies Unit (CTSU), Nuffield Department of Population Health, University of Oxford, Oxford, United Kingdom.

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http://dx.doi.org/10.1002/ijc.32148DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6767784PMC
September 2019

GWAS Identifies Risk Locus for Erectile Dysfunction and Implicates Hypothalamic Neurobiology and Diabetes in Etiology.

Am J Hum Genet 2019 01 21;104(1):157-163. Epub 2018 Dec 21.

National Institute for Health Research Oxford Biomedical Research Centre, Oxford University Hospital, Old Road, Oxford OX3 7LE, UK; Clinical Trial Service Unit & Epidemiological Studies Unit (CTSU), Nuffield Department of Population Health, Big Data Institute Building, Roosevelt Drive, University of Oxford, Oxford OX3 7LF, UK; Medical Research Council Population Health Research Unit at the University of Oxford, Nuffield Department of Population Health, University of Oxford, Oxford, UK.

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http://dx.doi.org/10.1016/j.ajhg.2018.11.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6323625PMC
January 2019

A review of lifestyle, metabolic risk factors, and blood-based biomarkers for early diagnosis of pancreatic ductal adenocarcinoma.

J Gastroenterol Hepatol 2019 Feb 17;34(2):330-345. Epub 2019 Jan 17.

Clinical Trial Service Unit & Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK.

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https://onlinelibrary.wiley.com/doi/abs/10.1111/jgh.14576
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http://dx.doi.org/10.1111/jgh.14576DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6378598PMC
February 2019

GWAS identifies 14 loci for device-measured physical activity and sleep duration.

Nat Commun 2018 12 10;9(1):5257. Epub 2018 Dec 10.

Big Data Institute, Li Ka Shing Centre for Health Information and Discovery, University of Oxford, Oxford, OX3 7LF, UK.

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http://dx.doi.org/10.1038/s41467-018-07743-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6288145PMC
December 2018

Research digest: genetics in cardiometabolic disease.

Lancet Diabetes Endocrinol 2018 12;6(12):922

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http://dx.doi.org/10.1016/S2213-8587(18)30318-8DOI Listing
December 2018

Influence of puberty timing on adiposity and cardiometabolic traits: A Mendelian randomisation study.

PLoS Med 2018 08 28;15(8):e1002641. Epub 2018 Aug 28.

Medical Research Council Integrative Epidemiology Unit, Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, United Kingdom.

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http://dx.doi.org/10.1371/journal.pmed.1002641DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6112630PMC
August 2018

Metabolic and lifestyle risk factors for acute pancreatitis in Chinese adults: A prospective cohort study of 0.5 million people.

PLoS Med 2018 08 1;15(8):e1002618. Epub 2018 Aug 1.

Clinical Trial Service Unit & Epidemiological Studies Unit (CTSU), Nuffield Department of Population Health, University of Oxford, Oxford, United Kingdom.

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http://dx.doi.org/10.1371/journal.pmed.1002618DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6070164PMC
August 2018

Reading Mendelian randomisation studies: a guide, glossary, and checklist for clinicians.

BMJ 2018 Jul 12;362:k601. Epub 2018 Jul 12.

Medical Research Council Integrative Epidemiology Unit, University of Bristol, BS8 2BN, UK

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6041728PMC
http://dx.doi.org/10.1136/bmj.k601DOI Listing
July 2018

Diabetes, plasma glucose and incidence of colorectal cancer in Chinese adults: a prospective study of 0.5 million people.

J Epidemiol Community Health 2018 10 3;72(10):919-925. Epub 2018 Jul 3.

Clinical Trial Service Unit & Epidemiological Studies Unit (CTSU), Nuffield Department of Population Health, University of Oxford, Oxford, UK.

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http://dx.doi.org/10.1136/jech-2018-210651DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6161653PMC
October 2018

Adiposity and risks of colorectal and small intestine cancer in Chinese adults: a prospective study of 0.5 million people.

Br J Cancer 2018 07 6;119(2):248-250. Epub 2018 Jun 6.

Clinical Trial Service Unit & Epidemiological Studies Unit (CTSU), Nuffield Department of Population Health, University of Oxford, Oxford, UK.

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http://dx.doi.org/10.1038/s41416-018-0124-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6048138PMC
July 2018

Problems in interpreting and using GWAS of conditional phenotypes illustrated by 'alcohol GWAS'.

Mol Psychiatry 2019 02 8;24(2):167-168. Epub 2018 Mar 8.

Medical Research Council Integrative Epidemiology Unit, University of Bristol, Bristol, BS8 2BN, UK.

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http://dx.doi.org/10.1038/s41380-018-0037-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6004313PMC
February 2019

Lipids, Lipoproteins, and Metabolites and Risk of Myocardial Infarction and Stroke.

J Am Coll Cardiol 2018 02;71(6):620-632

Clinical Trial Service Unit & Epidemiological Studies Unit (CTSU), Nuffield Department of Population Health, University of Oxford, Oxford, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.jacc.2017.12.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5811927PMC
February 2018

Challenges in Interpreting Multivariable Mendelian Randomization: Might "Good Cholesterol" Be Good After All?

Am J Kidney Dis 2018 02;71(2):149-153

Medical Research Council Integrative Epidemiology Unit, University of Bristol, Bristol, United Kingdom; Population Health Sciences, University of Bristol, Bristol, United Kingdom. Electronic address:

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http://dx.doi.org/10.1053/j.ajkd.2017.10.006DOI Listing
February 2018

Associations of General and Central Adiposity With Incident Diabetes in Chinese Men and Women.

Diabetes Care 2018 03 3;41(3):494-502. Epub 2018 Jan 3.

Clinical Trial Service Unit & Epidemiological Studies Unit (CTSU), Nuffield Department of Population Health, University of Oxford, Oxford, U.K.

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http://dx.doi.org/10.2337/dc17-1852DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6548563PMC
March 2018

Smoking, alcohol, and diet in relation to risk of pancreatic cancer in China: a prospective study of 0.5 million people.

Cancer Med 2018 01 22;7(1):229-239. Epub 2017 Dec 22.

Clinical Trial Service Unit & Epidemiological Studies Unit (CTSU), Nuffield Department of Population Health, University of Oxford, Oxford, United Kingdom.

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http://dx.doi.org/10.1002/cam4.1261DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5773963PMC
January 2018

Genetic Support for a Causal Role of Insulin Resistance on Circulating Branched-Chain Amino Acids and Inflammation.

Diabetes Care 2017 12 18;40(12):1779-1786. Epub 2017 Oct 18.

Computational Medicine, Faculty of Medicine, University of Oulu and Biocenter Oulu, Oulu, Finland

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http://dx.doi.org/10.2337/dc17-1642DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5701741PMC
December 2017

Impact of Selection Bias on Estimation of Subsequent Event Risk.

Circ Cardiovasc Genet 2017 10;10(5)

From the Department of Biostatistics and Bioinformatics, Emory University, Atlanta, GA (Y.-J.H., Z.L., P.L.); Groningen Research Institute of Pharmacy, University of Groningen, the Netherlands (A.F.S.); Institute of Cardiovascular Science and The Farr Institute, University College London, United Kingdom (A.F.S., A.D.H., F.W.A., R.P.); Department of Non-Communicable Disease Epidemiology, London School of Hygiene & Tropical Medicine, United Kingdom (F.D.); Department of Health Sciences, University of Leicester, United Kingdom (F.D.); Clinical Trial Service Unit & Epidemiological Studies Unit (CTSU), Nuffield Department of Population Health, University of Oxford, United Kingdom (M.V.H.); Medical Research Council Population Health Research Unit at the University of Oxford, United Kingdom (M.V.H.); Department of Medicine, McGill University, Montreal Quebec, Canada (J.M.B.); Division of Heart and Lungs, Department of Cardiology, University Medical Center Utrecht, The Netherlands (V.T., F.W.A.); Division of Cardiology, Department of Medicine, Emory Clinical Cardiovascular Research Institute, Emory University School of Medicine, Atlanta, GA (A.A.Q.); Intermountain Heart Institute, Intermountain Medical Center, Murray, UT (R.O.M., B.D.H.); Department of Biomedical Informatics, University of Utah, Salt Lake City (B.D.H.); and Department of Biostatistics and Epidemiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia (Q.L.).

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http://dx.doi.org/10.1161/CIRCGENETICS.116.001616DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5659743PMC
October 2017

Dyslipidaemia: Revealing the effect of CETP inhibition in cardiovascular disease.

Nat Rev Cardiol 2017 Nov 5;14(11):635-636. Epub 2017 Oct 5.

Medical Research Council Integrative Epidemiology Unit and the National Institute for Health Research Bristol Biomedical Research Centre, Oakfield House, Oakfield Grove, Bristol BS8 2BN, UK; and the School of Social and Community Medicine, University of Bristol, Barley House, Oakfield Grove, Bristol BS8 2BN, UK.

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http://dx.doi.org/10.1038/nrcardio.2017.156DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5644574PMC
November 2017

Genetic and epigenetic studies of adiposity and cardiometabolic disease.

Genome Med 2017 09 18;9(1):82. Epub 2017 Sep 18.

National Institute for Health Research, Oxford Biomedical Research Centre, Oxford University Hospital, Oxford, UK.

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http://dx.doi.org/10.1186/s13073-017-0474-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5604307PMC
September 2017

Young adulthood and adulthood adiposity in relation to incidence of pancreatic cancer: a prospective study of 0.5 million Chinese adults and a meta-analysis.

J Epidemiol Community Health 2017 Nov 12;71(11):1059-1067. Epub 2017 Sep 12.

Clinical Trial Service Unit and Epidemiological Studies Unit (CTSU), Nuffield Department of Population Health, University of Oxford, Oxford, UK.

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http://dx.doi.org/10.1136/jech-2017-208895DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5847093PMC
November 2017

Mendelian randomisation in cardiovascular research: an introduction for clinicians.

Heart 2017 09 8;103(18):1400-1407. Epub 2017 Jun 8.

Clinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK.

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http://dx.doi.org/10.1136/heartjnl-2016-310605DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5574403PMC
September 2017

Mendelian randomization in cardiometabolic disease: challenges in evaluating causality.

Nat Rev Cardiol 2017 Oct 1;14(10):577-590. Epub 2017 Jun 1.

Medical Research Council Integrative Epidemiology Unit, University of Bristol, Oakfield House, Oakfield Grove, Bristol BS8 2BN, UK.

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http://dx.doi.org/10.1038/nrcardio.2017.78DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5600813PMC
October 2017

Relations between lipoprotein(a) concentrations, LPA genetic variants, and the risk of mortality in patients with established coronary heart disease: a molecular and genetic association study.

Authors:
Stephen Zewinger Marcus E Kleber Vinicius Tragante Raymond O McCubrey Amand F Schmidt Kenan Direk Ulrich Laufs Christian Werner Wolfgang Koenig Dietrich Rothenbacher Ute Mons Lutz P Breitling Herrmann Brenner Richard T Jennings Ioannis Petrakis Sarah Triem Mira Klug Alexandra Filips Stefan Blankenberg Christoph Waldeyer Christoph Sinning Renate B Schnabel Karl J Lackner Efthymia Vlachopoulou Ottar Nygård Gard Frodahl Tveitevåg Svingen Eva Ringdal Pedersen Grethe S Tell Juha Sinisalo Markku S Nieminen Reijo Laaksonen Stella Trompet Roelof A J Smit Naveed Sattar J Wouter Jukema Heinrich V Groesdonk Graciela Delgado Tatjana Stojakovic Anna P Pilbrow Vicky A Cameron A Mark Richards Robert N Doughty Yan Gong Rhonda Cooper-DeHoff Julie Johnson Markus Scholz Frank Beutner Joachim Thiery J Gustav Smith Ragnar O Vilmundarson Ruth McPherson Alexandre F R Stewart Sharon Cresci Petra A Lenzini John A Spertus Oliviero Olivieri Domenico Girelli Nicola I Martinelli Andreas Leiherer Christoph H Saely Heinz Drexel Axel Mündlein Peter S Braund Christopher P Nelson Nilesh J Samani Daniel Kofink Imo E Hoefer Gerard Pasterkamp Arshed A Quyyumi Yi-An Ko Jaana A Hartiala Hooman Allayee W H Wilson Tang Stanley L Hazen Niclas Eriksson Claes Held Emil Hagström Lars Wallentin Axel Åkerblom Agneta Siegbahn Igor Karp Christopher Labos Louise Pilote James C Engert James M Brophy George Thanassoulis Peter Bogaty Wojciech Szczeklik Marcin Kaczor Marek Sanak Salim S Virani Christie M Ballantyne Vei-Vei Lee Eric Boerwinkle Michael V Holmes Benjamin D Horne Aroon Hingorani Folkert W Asselbergs Riyaz S Patel Bernhard K Krämer Hubert Scharnagl Danilo Fliser Winfried März Thimoteus Speer

Lancet Diabetes Endocrinol 2017 07 26;5(7):534-543. Epub 2017 May 26.

Department of Internal Medicine IV, Saarland University Hospital, Homburg/Saar, Germany.

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http://dx.doi.org/10.1016/S2213-8587(17)30096-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5651679PMC
July 2017

Causal Associations of Adiposity and Body Fat Distribution With Coronary Heart Disease, Stroke Subtypes, and Type 2 Diabetes Mellitus: A Mendelian Randomization Analysis.

Circulation 2017 Jun 12;135(24):2373-2388. Epub 2017 May 12.

From Farr Institute of Health Informatics Research, UCL Institute of Health Informatics, University College London, United Kingdom (C.E.D., G.F., D.P.-M., A.D.H., J.P.C.); Department of Mathematics and Statistics, Lancaster University, United Kingdom (T.M.P.); UCLGenetics Institute, University College London, United Kingdom (J.W.); Applied Statistical Methods in Medical Research Group, Universidad Catolica de San Antonio de Murcia, Spain (D.P.-M.); Social Genetic & Developmental Psychiatry, King's College London, United Kingdom (D.Z.); Institute of Cardiovascular Science, University College London, United Kingdom (J.E.L.E., T.S., A.D.H., S.E.H.); MRC Unit for Lifelong Health & Ageing at UCL, London, United Kingdom (A.W., D.K.); Clinical Pharmacology, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, United Kingdom (H.R.W., M.J.C., P.B.M.); NIHR Barts Cardiovascular Biomedical Research Unit, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, United Kingdom (H.R.W., M.J.C., P.B.M.); Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, United Kingdom (S.M., J.F.P.); Department of Cardiology, Leiden University Medical Center, The Netherlands (S.T., W.J.); South Australian Health and Medical Research Institute, Adelaide (M.M., E.H.); EMBL Australia, Adelaide (M.M.); School of Social and Community Medicine, University of Bristol, United Kingdom (R.W.M., T.R.G., Y.B.-S., D.A.L., G.D.S.); Centre for Clinical Pharmacology, University College London, United Kingdom (R.S.); Institute for Social and Economic Research, University of Essex, Colchester, United Kingdom (M.K.); Centre for Population Health Research, School of Health Sciences and Sansom Institute, University of South Australia, Adelaide (E.H., A.Z.); Population, Policy & Practice, UCL Great Ormond Street Institute of Child Health, London, United Kingdom (E.H., C.P.); Department of Primary Care & Population Health, University College London, Royal Free Campus, United Kingdom (B.J.J.); MRC Integrative Epidemiology Unit, University of Bristol, United Kingdom (T.R.G., D.A.L., G.D.S.); Department of Women's Cancer, Institute for Women's Health, UCL, London, United Kingdom (A.G.-M., A.R., U.M.); Department of Clinical Epidemiology, Leiden University Medical Center, The Netherlands (R.d.M., D.O.M.-K.); Department of Internal Medicine, Section Gerontology and Geriatrics, Leiden University Medical Center, The Netherlands (R.N., S.T.); Interuniversity Cardiology Institute Netherlands, Utrecht (W.J.); Departments of Neurology and Public Health Sciences, University of Virginia, Charlottesville (B.B.W.); Department of Public Health and Primary Care, Leiden University Medical Center, The Netherlands (D.O.M.-K.); BHF Glasgow Cardiovascular Research Centre, Faculty of Medicine, United Kingdom (N.S.); Department of Epidemiology and Public Health, University College London, United Kingdom (M.K.); Department of Non-communicable Disease Epidemiology, London School of Hygiene and Tropical Medicine, United Kingdom (F.D.); Department of Health Sciences, University of Leicester, United Kingdom (F.D.); Clinical Trial Service Unit & Epidemiological Studies Unit, Nuffield Department of Population Health, Big Data Institute Building, University of Oxford, United Kingdom (M.V.H.); Medical Research Council Population Health Research Unit at the University of Oxford, United Kingdom (M.V.H.); and National Institute for Health Research Oxford Biomedical Research Centre, Oxford University Hospitals, United Kingdom (M.V.H.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.116.026560DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5515354PMC
June 2017

Diabetes, plasma glucose and incidence of pancreatic cancer: A prospective study of 0.5 million Chinese adults and a meta-analysis of 22 cohort studies.

Int J Cancer 2017 Apr 8;140(8):1781-1788. Epub 2017 Feb 8.

Clinical Trial Service Unit & Epidemiological Studies Unit (CTSU), Nuffield Department of Population Health, University of Oxford, Oxford, United Kingdom.

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http://dx.doi.org/10.1002/ijc.30599DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5396360PMC
April 2017

Commentary: Mendelian randomization-inspired causal inference in the absence of genetic data.

Int J Epidemiol 2017 06;46(3):962-965

Clinical Trial Service Unit & Epidemiological Studies Unit (CTSU).

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http://dx.doi.org/10.1093/ije/dyw327DOI Listing
June 2017

PCSK9 genetic variants and risk of type 2 diabetes: a mendelian randomisation study.

Authors:
Amand F Schmidt Daniel I Swerdlow Michael V Holmes Riyaz S Patel Zammy Fairhurst-Hunter Donald M Lyall Fernando Pires Hartwig Bernardo Lessa Horta Elina Hyppönen Christine Power Max Moldovan Erik van Iperen G Kees Hovingh Ilja Demuth Kristina Norman Elisabeth Steinhagen-Thiessen Juri Demuth Lars Bertram Tian Liu Stefan Coassin Johann Willeit Stefan Kiechl Karin Willeit Dan Mason John Wright Richard Morris Goya Wanamethee Peter Whincup Yoav Ben-Shlomo Stela McLachlan Jackie F Price Mika Kivimaki Catherine Welch Adelaida Sanchez-Galvez Pedro Marques-Vidal Andrew Nicolaides Andrie G Panayiotou N Charlotte Onland-Moret Yvonne T van der Schouw Giuseppe Matullo Giovanni Fiorito Simonetta Guarrera Carlotta Sacerdote Nicholas J Wareham Claudia Langenberg Robert Scott Jian'an Luan Martin Bobak Sofia Malyutina Andrzej Pająk Ruzena Kubinova Abdonas Tamosiunas Hynek Pikhart Lise Lotte Nystrup Husemoen Niels Grarup Oluf Pedersen Torben Hansen Allan Linneberg Kenneth Starup Simonsen Jackie Cooper Steve E Humphries Murray Brilliant Terrie Kitchner Hakon Hakonarson David S Carrell Catherine A McCarty H Lester Kirchner Eric B Larson David R Crosslin Mariza de Andrade Dan M Roden Joshua C Denny Cara Carty Stephen Hancock John Attia Elizabeth Holliday Martin O'Donnell Salim Yusuf Michael Chong Guillaume Pare Pim van der Harst M Abdullah Said Ruben N Eppinga Niek Verweij Harold Snieder Tim Christen Dennis O Mook-Kanamori Stefan Gustafsson Lars Lind Erik Ingelsson Raha Pazoki Oscar Franco Albert Hofman Andre Uitterlinden Abbas Dehghan Alexander Teumer Sebastian Baumeister Marcus Dörr Markus M Lerch Uwe Völker Henry Völzke Joey Ward Jill P Pell Daniel J Smith Tom Meade Anke H Maitland-van der Zee Ekaterina V Baranova Robin Young Ian Ford Archie Campbell Sandosh Padmanabhan Michiel L Bots Diederick E Grobbee Philippe Froguel Dorothée Thuillier Beverley Balkau Amélie Bonnefond Bertrand Cariou Melissa Smart Yanchun Bao Meena Kumari Anubha Mahajan Paul M Ridker Daniel I Chasman Alex P Reiner Leslie A Lange Marylyn D Ritchie Folkert W Asselbergs Juan-Pablo Casas Brendan J Keating David Preiss Aroon D Hingorani Naveed Sattar

Lancet Diabetes Endocrinol 2017 02 29;5(2):97-105. Epub 2016 Nov 29.

Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, UK. Electronic address:

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http://dx.doi.org/10.1016/S2213-8587(16)30396-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5266795PMC
February 2017

Long-Term Survival and Freedom From Reintervention After Off-Pump Coronary Artery Bypass Grafting: A Propensity-Matched Study.

Circulation 2016 Oct;134(17):1209-1220

From the Department of Cardiothoracic Surgery, Liverpool Heart and Chest Hospital, United Kingdom (B.H.K., A.D.M.); MRC Population Health Research Unit, Clinical Trial Service Unit & Epidemiological Studies Unit (CTSU), Nuffield Department of Population Health, University of Oxford, United Kingdom (M.V.H.); and Clinical Trial Service Unit & Epidemiological Studies Unit (CTSU), Nuffield Department of Population Health, University of Oxford, United Kingdom (M.V.H.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.116.021933DOI Listing
October 2016

Genetic analysis of emerging risk factors in coronary artery disease.

Atherosclerosis 2016 11 13;254:35-41. Epub 2016 Sep 13.

Durrer Center for Cardiovascular Research, Netherlands Heart Institute, Utrecht, The Netherlands; Department of Cardiology, Division of Heart and Lungs, University Medical Center Utrecht, Utrecht, The Netherlands; Institute of Cardiovascular Science, Faculty of Population Health Sciences, University College London, London, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.atherosclerosis.2016.09.008DOI Listing
November 2016

Cystatin C and Cardiovascular Disease: A Mendelian Randomization Study.

J Am Coll Cardiol 2016 08;68(9):934-45

Department of Cardiology, Division Heart and Lungs, University Medical Center Utrecht, Utrecht, the Netherlands; Durrer Center for Cardiogenetic Research, ICIN-Netherlands Heart Institute, Utrecht, the Netherlands; Institute of Cardiovascular Science, Faculty of Population Health Sciences, University College London, London, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.jacc.2016.05.092DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5451109PMC
August 2016

An ectopically expressed serum miRNA signature is prognostic, diagnostic, and biologically related to liver allograft rejection.

Hepatology 2017 01 5;65(1):269-280. Epub 2016 Oct 5.

Penn Transplant Institute, Hospital of the University of Pennsylvania, Philadelphia, PA.

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http://dx.doi.org/10.1002/hep.28786DOI Listing
January 2017

Association of Lipid Fractions With Risks for Coronary Artery Disease and Diabetes.

JAMA Cardiol 2016 09;1(6):692-9

Clinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford, England.

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http://dx.doi.org/10.1001/jamacardio.2016.1884DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5642865PMC
September 2016

Validity of COPD diagnoses reported through nationwide health insurance systems in the People's Republic of China.

Int J Chron Obstruct Pulmon Dis 2016 1;11:419-30. Epub 2016 Mar 1.

Clinical Trial Service Unit & Epidemiological Studies Unit (CTSU), Nuffield Department of Population Health, University of Oxford, Oxford, UK.

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http://dx.doi.org/10.2147/COPD.S100736DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4780206PMC
January 2017

Deciphering the Causal Role of sPLA2s and Lp-PLA2 in Coronary Heart Disease.

Arterioscler Thromb Vasc Biol 2015 Nov 3;35(11):2281-9. Epub 2015 Sep 3.

From the Center for Cardiovascular Genetics, Institute of Cardiovascular Science, University College London, London, UK (P.J.T.); and Clinical Trial Service Unit & Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK (M.V.H.).

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http://dx.doi.org/10.1161/ATVBAHA.115.305234DOI Listing
November 2015