Publications by authors named "Michael T McManus"

100Publications

Macrophage Exosomes Resolve Atherosclerosis by Regulating Hematopoiesis and Inflammation via MicroRNA Cargo.

Cell Rep 2020 Jul;32(2):107881

Department of Surgery, Division of Vascular and Endovascular Surgery, University of California, San Francisco, San Francisco, CA 94143, USA; Northern California Institute for Research and Education, San Francisco, CA 94121, USA; Department of Veterans Affairs, Surgical Service (112G), San Francisco VA Medical Center, San Francisco, CA 94121, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2020.107881DOI Listing
July 2020

CD81 Controls Beige Fat Progenitor Cell Growth and Energy Balance via FAK Signaling.

Cell 2020 Aug 1;182(3):563-577.e20. Epub 2020 Jul 1.

UCSF Diabetes Center, University of California, San Francisco, San Francisco, CA, USA; Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, University of California, San Francisco, San Francisco, CA, USA; Department of Cell and Tissue Biology, University of California, San Francisco, San Francisco, CA, USA; Beth Israel Deaconess Medical Center, Division of Endocrinology, Diabetes & Metabolism, Harvard Medical School, Boston, MA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2020.06.021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7415677PMC
August 2020

miR-15/16 Restrain Memory T Cell Differentiation, Cell Cycle, and Survival.

Cell Rep 2019 08;28(8):2169-2181.e4

Department of Microbiology and Immunology, University of California, San Francisco, San Francisco, CA 94143, USA; Sandler Asthma Basic Research Center, University of California, San Francisco, San Francisco, CA 94143, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2019.07.064DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6715152PMC
August 2019

Genomic Resolution of DLX-Orchestrated Transcriptional Circuits Driving Development of Forebrain GABAergic Neurons.

Cell Rep 2019 08;28(8):2048-2063.e8

Nina Ireland Laboratory of Developmental Neurobiology, Department of Psychiatry, UCSF Weill Institute for Neurosciences, University of California, San Francisco, San Francisco, CA 94158, USA; Development and Stem Cell Biology Program, University of California, San Francisco, San Francisco, CA 94158, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2019.07.022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6750766PMC
August 2019

Thermoregulation via Temperature-Dependent PGD Production in Mouse Preoptic Area.

Neuron 2019 07 28;103(2):309-322.e7. Epub 2019 May 28.

Departments of Physiology, Biochemistry and Biophysics, University of California, San Francisco, San Francisco, CA 94158, USA; Howard Hughes Medical Institute, University of California, San Francisco, San Francisco, CA 94158, USA. Electronic address:

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http://dx.doi.org/10.1016/j.neuron.2019.04.035DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6639135PMC
July 2019

Tracing cellular heterogeneity in pooled genetic screens via multi-level barcoding.

BMC Genomics 2019 Feb 6;20(1):107. Epub 2019 Feb 6.

Department of Microbiology and Immunology, UCSF Diabetes Center, University of California, San Francisco, San Francisco, CA, 94143, USA.

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http://dx.doi.org/10.1186/s12864-019-5480-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6364396PMC
February 2019

Far away from the lamppost.

PLoS Biol 2018 12 11;16(12):e3000067. Epub 2018 Dec 11.

Department of Microbiology and Immunology, UCSF Diabetes Center, University of California-San Francisco, San Francisco, California, United States of America.

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http://dx.doi.org/10.1371/journal.pbio.3000067DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6289406PMC
December 2018

miR-205 Regulates Basal Cell Identity and Stem Cell Regenerative Potential During Mammary Reconstitution.

Stem Cells 2018 12 31;36(12):1875-1889. Epub 2018 Oct 31.

Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, Texas.

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http://dx.doi.org/10.1002/stem.2914DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6379077PMC
December 2018

Drought-induced senescence of Medicago truncatula nodules involves serpin and ferritin to control proteolytic activity and iron levels.

New Phytol 2018 10 5;220(1):196-208. Epub 2018 Jul 5.

Institute of Fundamental Sciences, Massey University, Private Bag 11-222, Palmerston North, New Zealand.

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http://dx.doi.org/10.1111/nph.15298DOI Listing
October 2018

Insights into carotenoid accumulation using VIGS to block different steps of carotenoid biosynthesis in petals of California poppy.

Plant Cell Rep 2018 Sep 19;37(9):1311-1323. Epub 2018 Jun 19.

The New Zealand Institute for Plant & Food Research Limited, Private Bag 11600, Palmerston North, New Zealand.

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http://dx.doi.org/10.1007/s00299-018-2314-5DOI Listing
September 2018

The Transcriptionally Permissive Chromatin State of Embryonic Stem Cells Is Acutely Tuned to Translational Output.

Cell Stem Cell 2018 03;22(3):369-383.e8

Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, Center for Reproductive Sciences and Diabetes Center, University of California, San Francisco, San Francisco, CA 94143, USA. Electronic address:

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http://dx.doi.org/10.1016/j.stem.2018.02.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5836508PMC
March 2018

Dual Strategies for Argonaute2-Mediated Biogenesis of Erythroid miRNAs Underlie Conserved Requirements for Slicing in Mammals.

Mol Cell 2018 01;69(2):265-278.e6

Department of Developmental Biology, Sloan Kettering Institute, 1275 York Ave., Box 252, New York, NY 10065, USA; Weill Graduate School of Medical Sciences, Cornell University, New York, NY 10065, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S10972765173098
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http://dx.doi.org/10.1016/j.molcel.2017.12.027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5824974PMC
January 2018

Dual gene activation and knockout screen reveals directional dependencies in genetic networks.

Nat Biotechnol 2018 02 15;36(2):170-178. Epub 2018 Jan 15.

Department of Microbiology and Immunology, University of California San Francisco Diabetes Center, WM Keck Center for Noncoding RNAs, University of California, San Francisco, San Francisco, California, USA.

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http://dx.doi.org/10.1038/nbt.4062DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6072461PMC
February 2018

Selenium treatment differentially affects sulfur metabolism in high and low glucosinolate producing cultivars of broccoli (Brassica oleracea L.).

Plant Physiol Biochem 2017 Dec 31;121:176-186. Epub 2017 Oct 31.

Institute of Fundamental Sciences, Massey University, Private Bag 11222, Palmerston North, New Zealand.

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http://dx.doi.org/10.1016/j.plaphy.2017.10.027DOI Listing
December 2017

Drug-tolerant persister cancer cells are vulnerable to GPX4 inhibition.

Nature 2017 11 1;551(7679):247-250. Epub 2017 Nov 1.

Department of Microbiology and Immunology, University of California San Francisco, 513 Parnassus Avenue, San Francisco, California 94143, USA.

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http://www.nature.com/doifinder/10.1038/nature24297
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http://dx.doi.org/10.1038/nature24297DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5933935PMC
November 2017

Kunitz Proteinase Inhibitors Limit Water Stress Responses in White Clover ( L.) Plants.

Front Plant Sci 2017 4;8:1683. Epub 2017 Oct 4.

Institute of Fundamental Sciences, Massey University, Palmerston North, New Zealand.

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http://dx.doi.org/10.3389/fpls.2017.01683DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5632647PMC
October 2017

Defining epithelial cell dynamics and lineage relationships in the developing lacrimal gland.

Development 2017 07 2;144(13):2517-2528. Epub 2017 Jun 2.

Department of Cell and Tissue Biology, University of California, San Francisco, CA, 94143, USA

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http://dx.doi.org/10.1242/dev.150789DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5536870PMC
July 2017

miR-205 is a critical regulator of lacrimal gland development.

Dev Biol 2017 07 13;427(1):12-20. Epub 2017 May 13.

Department of Microbiology and Immunology, University of California, San Francisco, CA, USA; UCSF Diabetes Center, University of California, San Francisco, CA, USA; WM Keck Center for Noncoding RNAs, University of California, San Francisco, CA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ydbio.2017.05.012DOI Listing
July 2017

MicroRNAs in ectodermal appendages.

Curr Opin Genet Dev 2017 Apr 16;43:61-66. Epub 2017 Jan 16.

Department of Microbiology and Immunology, University of California, San Francisco, CA, USA; UCSF Diabetes Center, University of California, San Francisco, CA, USA; WM Keck Center for Noncoding RNAs, University of California, San Francisco, CA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.gde.2016.12.006DOI Listing
April 2017

Phosphate availability regulates ethylene biosynthesis gene expression and protein accumulation in white clover (Trifolium repens L.) roots.

Biosci Rep 2016 12 17;36(6). Epub 2016 Nov 17.

Institute of Fundamental Sciences, Massey University, Private Bag 11222, Palmerston North 4474, New Zealand.

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http://dx.doi.org/10.1042/BSR20160148DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5293567PMC
December 2016

MicroRNAs 24 and 27 Suppress Allergic Inflammation and Target a Network of Regulators of T Helper 2 Cell-Associated Cytokine Production.

Immunity 2016 Apr 2;44(4):821-32. Epub 2016 Feb 2.

Department of Microbiology and Immunology, University of California, San Francisco, San Francisco, CA, USA; Sandler Asthma Basic Research Center, University of California, San Francisco, San Francisco CA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2016.01.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4838571PMC
April 2016

Knock-down of transcript abundance of a family of Kunitz proteinase inhibitor genes in white clover (Trifolium repens) reveals a redundancy and diversity of gene function.

New Phytol 2015 Dec 17;208(4):1188-201. Epub 2015 Sep 17.

Institute of Fundamental Sciences, Massey University, Private Bag 11-222, Palmerston North, New Zealand.

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http://dx.doi.org/10.1111/nph.13543DOI Listing
December 2015

Identification of MiR-205 As a MicroRNA That Is Highly Expressed in Medullary Thymic Epithelial Cells.

PLoS One 2015 13;10(8):e0135440. Epub 2015 Aug 13.

UCSF Diabetes Center, University of California San Francisco, San Francisco, California, United States of America; Department of Medicine, University of California San Francisco, San Francisco, California, United States of America; Department of Pathology, University of California San Francisco, San Francisco, California, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0135440PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4535774PMC
May 2016

Choosing the Right Tool for the Job: RNAi, TALEN, or CRISPR.

Mol Cell 2015 May;58(4):575-85

Department of Microbiology and Immunology, UCSF Diabetes Center, Keck Center for Noncoding RNA, University of California, San Francisco, San Francisco, CA 94143, USA. Electronic address:

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http://dx.doi.org/10.1016/j.molcel.2015.04.028DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4441801PMC
May 2015

Integrative analysis of 111 reference human epigenomes.

Nature 2015 Feb;518(7539):317-30

1] Computer Science and Artificial Intelligence Lab, Massachusetts Institute of Technology, 32 Vassar St, Cambridge, Massachusetts 02139, USA. [2] The Broad Institute of Harvard and MIT, 415 Main Street, Cambridge, Massachusetts 02142, USA.

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http://dx.doi.org/10.1038/nature14248DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4530010PMC
February 2015

A screen in mice uncovers repression of lipoprotein lipase by microRNA-29a as a mechanism for lipid distribution away from the liver.

Hepatology 2015 Jan 24;61(1):141-52. Epub 2014 Nov 24.

Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, University of California San Francisco, San Francisco, CA; Department of Pathology, University of California San Francisco, San Francisco, CA; Liver Center, University of California San Francisco, San Francisco, CA.

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http://dx.doi.org/10.1002/hep.27379DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4465779PMC
January 2015

Systematic identification of barriers to human iPSC generation.

Cell 2014 Jul;158(2):449-461

Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, University of California, San Francisco, San Francisco, CA 94143, USA; Departments of Ob/Gyn and Pathology, Center for Reproductive Sciences, and Diabetes Center, University of California, San Francisco, San Francisco, CA 94143, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2014.05.040DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4130998PMC
July 2014

Massively parallel functional annotation of 3' untranslated regions.

Nat Biotechnol 2014 Apr 16;32(4):387-91. Epub 2014 Mar 16.

Lung Biology Center, University of California San Francisco, San Francisco, California, USA.

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http://dx.doi.org/10.1038/nbt.2851DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3981918PMC
April 2014

Negative regulation of Hif1a expression and TH17 differentiation by the hypoxia-regulated microRNA miR-210.

Nat Immunol 2014 Apr 9;15(4):393-401. Epub 2014 Mar 9.

Departments of Medicine and of Microbiology & Immunology, the Rosalind Russell-Ephraim P. Engleman Medical Research Center for Arthritis, and the Howard Hughes Medical Institute, University of California, San Francisco, CA 94143.

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http://dx.doi.org/10.1038/ni.2846DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3996831PMC
April 2014

Partially penetrant postnatal lethality of an epithelial specific MicroRNA in a mouse knockout.

PLoS One 2013 7;8(10):e76634. Epub 2013 Oct 7.

Department of Microbiology and Immunology, University of California San Francisco, San Francisco, California, United States of America ; UCSF Diabetes Center, University of California San Francisco, San Francisco, California, United States of America ; WM Keck Center for Noncoding RNAs, University of California San Francisco, San Francisco, California, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0076634PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3792019PMC
August 2014

The X-ray crystal structure of APR-B, an atypical adenosine 5'-phosphosulfate reductase from Physcomitrella patens.

FEBS Lett 2013 Nov 4;587(22):3626-32. Epub 2013 Oct 4.

Department of Biological Chemistry, John Innes Centre, Norwich Research Park, Norwich NR4 7UH, UK.

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http://dx.doi.org/10.1016/j.febslet.2013.09.034DOI Listing
November 2013

The Pitx2:miR-200c/141:noggin pathway regulates Bmp signaling and ameloblast differentiation.

Development 2013 Aug 17;140(16):3348-59. Epub 2013 Jul 17.

Department of Anatomy and Cell Biology, The University of Iowa, Iowa City, IA 52242, USA.

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http://dx.doi.org/10.1242/dev.089193DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3737717PMC
August 2013

Pervasive transcription of the human genome produces thousands of previously unidentified long intergenic noncoding RNAs.

PLoS Genet 2013 Jun 20;9(6):e1003569. Epub 2013 Jun 20.

Diabetes Center, Department of Microbiology and Immunology, University of California, San Francisco, California, USA.

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http://dx.doi.org/10.1371/journal.pgen.1003569DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3688513PMC
June 2013

Renewable RNAi.

Nat Biotechnol 2013 Apr;31(4):319-20

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http://dx.doi.org/10.1038/nbt.2547DOI Listing
April 2013

A systematic mammalian genetic interaction map reveals pathways underlying ricin susceptibility.

Cell 2013 Feb 8;152(4):909-22. Epub 2013 Feb 8.

Department of Cellular and Molecular Pharmacology, California Institute for Quantitative Biomedical Research and Howard Hughes Medical Institute, University of California, San Francisco, San Francisco, CA 94122, USA.

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http://dx.doi.org/10.1016/j.cell.2013.01.030DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3652613PMC
February 2013

Genotypic variation in sulfur assimilation and metabolism of onion (Allium cepa L.) III. Characterization of sulfite reductase.

Phytochemistry 2012 Nov 31;83:34-42. Epub 2012 Aug 31.

Institute of Molecular BioSciences, Massey University, Private Bag 11222, Palmerston North, New Zealand.

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http://dx.doi.org/10.1016/j.phytochem.2012.07.028DOI Listing
November 2012

Research resource: RNA-Seq reveals unique features of the pancreatic β-cell transcriptome.

Mol Endocrinol 2012 Oct 21;26(10):1783-92. Epub 2012 Aug 21.

513 Parnassus Avenue, Box 0534, San Francisco, California 94143-0534, USA.

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http://dx.doi.org/10.1210/me.2012-1176DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3458219PMC
October 2012

Precursor microRNA-programmed silencing complex assembly pathways in mammals.

Mol Cell 2012 May 12;46(4):507-17. Epub 2012 Apr 12.

Department of Pathology and Laboratory Medicine, Division of Neuropathology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1016/j.molcel.2012.03.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3399505PMC
May 2012

Widespread RNA 3'-end oligouridylation in mammals.

RNA 2012 Mar 30;18(3):394-401. Epub 2012 Jan 30.

Biomedical Sciences Graduate Program, University of California, San Francisco, San Francisco, California 94143, USA.

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http://dx.doi.org/10.1261/rna.029306.111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3285928PMC
March 2012

An siRNA screen in pancreatic beta cells reveals a role for Gpr27 in insulin production.

PLoS Genet 2012 Jan 12;8(1):e1002449. Epub 2012 Jan 12.

Diabetes Center, University of California San Francisco, CA, USA.

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http://dx.doi.org/10.1371/journal.pgen.1002449DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3257298PMC
January 2012

Polymerase II promoter strength determines efficacy of microRNA adapted shRNAs.

PLoS One 2011 21;6(10):e26213. Epub 2011 Oct 21.

Department of Microbiology and Immunology, Diabetes Center, University of California San Francisco, San Francisco, California, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0026213PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3198731PMC
May 2012

Changes in 1-aminocyclopropane-1-carboxlate (ACC) oxidase expression and enzyme activity in response to excess manganese in white clover (Trifolium repens L.).

Plant Physiol Biochem 2011 Sep 13;49(9):1013-9. Epub 2011 Apr 13.

Institute of Molecular Biosciences, Massey University, Private Bag 11222, Palmerston North, New Zealand.

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https://linkinghub.elsevier.com/retrieve/pii/S09819428110013
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http://dx.doi.org/10.1016/j.plaphy.2011.04.007DOI Listing
September 2011

Genotypic variation in the sulfur assimilation and metabolism of onion (Allium cepa L.) I. Plant composition and transcript accumulation.

Phytochemistry 2011 Jun 4;72(9):882-7. Epub 2011 Apr 4.

Institute of Molecular BioSciences, Massey University, Private Bag 11222, Palmerston North, New Zealand.

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http://dx.doi.org/10.1016/j.phytochem.2011.03.006DOI Listing
June 2011

Genotypic variation in sulphur assimilation and metabolism of onion (Allium cepa L.). II: Characterisation of ATP sulphurylase activity.

Phytochemistry 2011 Jun 1;72(9):888-96. Epub 2011 Apr 1.

Institute of Molecular BioSciences, Massey University, Private Bag 11222, Palmerston North, New Zealand.

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http://dx.doi.org/10.1016/j.phytochem.2011.03.001DOI Listing
June 2011

ACC oxidase (ACO) genes in Trifolium occidentale (L.) and their relationship to ACO genes in white clover (T. repens L.) and T. pallescens (L.).

Plant Physiol Biochem 2011 Apr 21;49(4):420-6. Epub 2011 Jan 21.

Institute of Molecular Biosciences, Massey University, Palmerston North, New Zealand.

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http://dx.doi.org/10.1016/j.plaphy.2011.01.017DOI Listing
April 2011

The microRNA-processing enzyme Dicer is dispensable for somite segmentation but essential for limb bud positioning.

Dev Biol 2011 Mar 20;351(2):254-65. Epub 2011 Jan 20.

Laboratory of Genetics, University of Wisconsin-Madison, Madison, WI 53706, USA.

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http://dx.doi.org/10.1016/j.ydbio.2011.01.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3541530PMC
March 2011

Posttranscriptional silencing of effector cytokine mRNA underlies the anergic phenotype of self-reactive T cells.

Immunity 2011 Jan 13;34(1):50-60. Epub 2011 Jan 13.

Department of Pathology, University of California, San Francisco, San Francisco, CA 94143, USA.

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http://dx.doi.org/10.1016/j.immuni.2010.12.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3955755PMC
January 2011

Analysis of microRNA knockouts in mice.

Hum Mol Genet 2010 Oct 30;19(R2):R169-75. Epub 2010 Aug 30.

UCSF Diabetes Center, University of California-San Francisco, 513 Parnassus Avenue, San Francisco, CA 94143-0534, USA.

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https://hmg.oxfordjournals.org/content/19/R2/R169.full.pdf
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http://www.hmg.oxfordjournals.org/cgi/doi/10.1093/hmg/ddq367
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http://dx.doi.org/10.1093/hmg/ddq367DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2981466PMC
October 2010

Dicer ablation in oligodendrocytes provokes neuronal impairment in mice.

Ann Neurol 2009 Dec;66(6):843-57

Department of Neurology, University of California San Francisco, San Francisco, CA 94158, USA.

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http://dx.doi.org/10.1002/ana.21927DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2885004PMC
December 2009

Expanded RNA-binding activities of mammalian Argonaute 2.

Nucleic Acids Res 2009 Dec;37(22):7533-45

Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1093/nar/gkp812DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2794174PMC
December 2009

Dicer is required for proper liver zonation.

J Pathol 2009 Nov;219(3):365-72

Pathology Division, National Cancer Center Research Institute, 5-1-1, Tsukiji, Chuo-ku, Tokyo, Japan.

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http://dx.doi.org/10.1002/path.2606DOI Listing
November 2009

Chd1 regulates open chromatin and pluripotency of embryonic stem cells.

Nature 2009 Aug 8;460(7257):863-8. Epub 2009 Jul 8.

Department of Ob/Gyn and Pathology, Center for Reproductive Sciences and Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research, University of California, San Francisco, 513 Parnassus Avenue, San Francisco, California 94143-0525, USA.

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http://dx.doi.org/10.1038/nature08212DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3891576PMC
August 2009

Rapid creation and quantitative monitoring of high coverage shRNA libraries.

Nat Methods 2009 Jun 17;6(6):443-5. Epub 2009 May 17.

Department of Cellular and Molecular Pharmacology, California Institute for Quantitative Biomedical Research, Howard Hughes Medical Institute, University of California, San Francisco, California, USA.

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http://dx.doi.org/10.1038/nmeth.1330DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2783737PMC
June 2009

LPS induces KH-type splicing regulatory protein-dependent processing of microRNA-155 precursors in macrophages.

FASEB J 2009 Sep 7;23(9):2898-908. Epub 2009 May 7.

RNA Technology Laboratory, Centro Biotecnologie Avanzate, Genoa, Italy.

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http://dx.doi.org/10.1096/fj.09-131342DOI Listing
September 2009

Up-regulation of miR-21 by HER2/neu signaling promotes cell invasion.

J Biol Chem 2009 Jul 6;284(27):18515-24. Epub 2009 May 6.

Department of Microbiology and Immunology, University of California, San Francisco, California 94143, USA.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M109.006676
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http://dx.doi.org/10.1074/jbc.M109.006676DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2709372PMC
July 2009

Residual microRNA expression dictates the extent of inner ear development in conditional Dicer knockout mice.

Dev Biol 2009 Apr 4;328(2):328-41. Epub 2009 Feb 4.

Department of Biomedical Sciences, Creighton University School of Medicine, 2500 California Plaza, Omaha, NE 68178, USA.

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http://dx.doi.org/10.1016/j.ydbio.2009.01.037DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2793102PMC
April 2009

Disruption of Dicer1 induces dysregulated fetal gene expression and promotes hepatocarcinogenesis.

Gastroenterology 2009 Jun 6;136(7):2304-2315.e1-4. Epub 2009 Mar 6.

Pathology Division, National Cancer Center Research Institute, Tokyo, Japan.

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http://dx.doi.org/10.1053/j.gastro.2009.02.067DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3167383PMC
June 2009

Characterization of the 1-aminocyclopropane-1-carboxylic acid (ACC) oxidase multigene family of Malus domestica Borkh.

Phytochemistry 2009 Feb 14;70(3):348-60. Epub 2009 Feb 14.

Institute of Molecular Biosciences, Massey University, Private Bag 11222, Palmerston North, New Zealand.

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http://dx.doi.org/10.1016/j.phytochem.2009.01.002DOI Listing
February 2009

Genetic analyses reveal a requirement for Dicer1 in the mouse urogenital tract.

Mamm Genome 2009 Mar 24;20(3):140-51. Epub 2009 Jan 24.

Mammalian Genetics Unit, MRC Harwell, Oxfordshire, OX11 0RD, UK.

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http://dx.doi.org/10.1007/s00335-008-9169-yDOI Listing
March 2009

Sertoli cell Dicer is essential for spermatogenesis in mice.

Dev Biol 2009 Feb 28;326(1):250-9. Epub 2008 Nov 28.

Department of Genetic Medicine and Development, University of Geneva Medical School, 1, rue Michel Servet, 1211 Geneva 4, Switzerland.

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http://dx.doi.org/10.1016/j.ydbio.2008.11.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2705812PMC
February 2009

Podocyte-specific deletion of dicer alters cytoskeletal dynamics and causes glomerular disease.

J Am Soc Nephrol 2008 Nov 5;19(11):2150-8. Epub 2008 Sep 5.

Renal Division, Washington University School of Medicine, St. Louis, MO 63110, USA.

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http://dx.doi.org/10.1681/ASN.2008020233DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2573015PMC
November 2008

Selective miRNA disruption in T reg cells leads to uncontrolled autoimmunity.

J Exp Med 2008 Sep 25;205(9):1983-91. Epub 2008 Aug 25.

Diabetes Center, University of California, San Francisco, San Francisco, CA 94143, USA.

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http://dx.doi.org/10.1084/jem.20080707DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2526194PMC
September 2008

Dicer1 is required for differentiation of the mouse male germline.

Biol Reprod 2008 Oct 16;79(4):696-703. Epub 2008 Jul 16.

Department of Microbiology and Immunology, University of California San Francisco Diabetes Center, San Francisco, California 94143, USA.

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http://dx.doi.org/10.1095/biolreprod.108.067827DOI Listing
October 2008

Conditional loss of Dicer disrupts cellular and tissue morphogenesis in the cortex and hippocampus.

J Neurosci 2008 Apr;28(17):4322-30

Department of Ophthalmology, University of California, San Francisco, San Francisco, California 94143-0730, USA.

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http://dx.doi.org/10.1523/JNEUROSCI.4815-07.2008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3844796PMC
April 2008

Lentiviral strategies for RNAi knockdown of neuronal genes.

Curr Protoc Neurosci 2007 Apr;Chapter 5:Unit 5.26

Massachusetts Institute of Technology, Cambridge, Massachusetts, USA.

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http://dx.doi.org/10.1002/0471142301.ns0526s39DOI Listing
April 2007

Dicer loss in striatal neurons produces behavioral and neuroanatomical phenotypes in the absence of neurodegeneration.

Proc Natl Acad Sci U S A 2008 Apr 2;105(14):5614-9. Epub 2008 Apr 2.

Department of Microbiology and Immunology, Diabetes Center, Biomedical Sciences Graduate Program, and Departments of Ophthalmology and Physiology, University of California, San Francisco, CA 94122-0534, USA.

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http://dx.doi.org/10.1073/pnas.0801689105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2291142PMC
April 2008

Unintentional miRNA ablation is a risk factor in gene knockout studies: a short report.

PLoS Genet 2008 Feb;4(2):e34

Department of Microbiology and Immunology, University of California San Francisco Diabetes Center, University of California San Francisco, San Francisco, California, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.0040034DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2242815PMC
February 2008

Behind the scenes of a small RNA gene-silencing pathway.

Hum Gene Ther 2008 Jan;19(1):17-26

Division of Endocrinology and Metabolism, Department of Medicine, University of California, San Francisco, San Francisco, CA 94122, USA.

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http://dx.doi.org/10.1089/hum.2007.1226DOI Listing
January 2008