Publications by authors named "Michael T Dill"

26Publications

Regenerative Reprogramming of the Intestinal Stem Cell State via Hippo Signaling Suppresses Metastatic Colorectal Cancer.

Authors:
Priscilla Cheung Jordi Xiol Michael T Dill Wei-Chien Yuan Riccardo Panero Jatin Roper Fernando G Osorio Dejan Maglic Qi Li Basanta Gurung Raffaele A Calogero Ömer H Yilmaz Junhao Mao Fernando D Camargo

Cell Stem Cell 2020 Oct 29;27(4):590-604.e9. Epub 2020 Jul 29.

Stem Cell Program, Boston Children's Hospital, Boston, MA 02115, USA; Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA 02138, USA. Electronic address:

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October 2020

Single-Cell Analysis of the Liver Epithelium Reveals Dynamic Heterogeneity and an Essential Role for YAP in Homeostasis and Regeneration.

Authors:
Brian J Pepe-Mooney Michael T Dill Anna Alemany Jose Ordovas-Montanes Yuki Matsushita Anuradha Rao Anushna Sen Makoto Miyazaki Sayeepriyadarshini Anakk Paul A Dawson Noriaki Ono Alex K Shalek Alexander van Oudenaarden Fernando D Camargo

Cell Stem Cell 2019 07 9;25(1):23-38.e8. Epub 2019 May 9.

Stem Cell Program, Boston Children's Hospital, Boston, MA 02115, USA; Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA 02138, USA; Harvard Stem Cell Institute, Boston, MA 02115, USA. Electronic address:

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July 2019

NUAK2 is a critical YAP target in liver cancer.

Authors:
Wei-Chien Yuan Brian Pepe-Mooney Giorgio G Galli Michael T Dill Hai-Tsang Huang Mingfeng Hao Yumeng Wang Han Liang Raffaele A Calogero Fernando D Camargo

Nat Commun 2018 11 16;9(1):4834. Epub 2018 Nov 16.

Stem Cell Program, Boston Children's Hospital, Boston, MA, 02115, USA.

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November 2018

Comprehensive Molecular Characterization of the Hippo Signaling Pathway in Cancer.

Authors:
Yumeng Wang Xiaoyan Xu Dejan Maglic Michael T Dill Kamalika Mojumdar Patrick Kwok-Shing Ng Kang Jin Jeong Yiu Huen Tsang Daniela Moreno Venkata Hemanjani Bhavana Xinxin Peng Zhongqi Ge Hu Chen Jun Li Zhongyuan Chen Huiwen Zhang Leng Han Di Du Chad J Creighton Gordon B Mills Fernando Camargo Han Liang

Cell Rep 2018 10;25(5):1304-1317.e5

Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA; Graduate Program in Quantitative and Computational Biosciences, Baylor College of Medicine, Houston, TX 77030, USA; Department of Systems Biology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA. Electronic address:

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October 2018

YAP-TEAD signaling promotes basal cell carcinoma development via a c-JUN/AP1 axis.

Authors:
Dejan Maglic Karin Schlegelmilch Antonella Fm Dost Riccardo Panero Michael T Dill Raffaele A Calogero Fernando D Camargo

EMBO J 2018 09 23;37(17). Epub 2018 Jul 23.

Stem Cell Program, Boston Children's Hospital, Boston, MA, USA

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September 2018

Corrigendum: The RSPO-LGR4/5-ZNRF3/RNF43 module controls liver zonation and size.

Authors:
Lara Planas-Paz Vanessa Orsini Luke Boulter Diego Calabrese Monika Pikiolek Florian Nigsch Yang Xie Guglielmo Roma Adriana Donovan Patricia Marti Nicolau Beckmann Michael T Dill Walter Carbone Sebastian Bergling Andrea Isken Matthias Mueller Bernd Kinzel Yi Yang Xiaohong Mao Thomas B Nicholson Raffaella Zamponi Paola Capodieci Reginald Valdez Daniel Rivera Andreas Loew Chinweike Ukomadu Luigi M Terracciano Tewis Bouwmeester Feng Cong Markus H Heim Stuart J Forbes Heinz Ruffner Jan S Tchorz

Nat Cell Biol 2016 10;18(11):1260

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October 2016

Gene expression analysis of biopsy samples reveals critical limitations of transcriptome-based molecular classifications of hepatocellular carcinoma.

Authors:
Zuzanna Makowska Tujana Boldanova David Adametz Luca Quagliata Julia E Vogt Michael T Dill Mathias S Matter Volker Roth Luigi Terracciano Markus H Heim

J Pathol Clin Res 2016 Apr 5;2(2):80-92. Epub 2016 Feb 5.

Department of BiomedicineUniversity of BaselBaselSwitzerland; Division of Hepatology and GastroenterologyUniversity Hospital of BaselBaselSwitzerland.

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April 2016

Hepatic Notch1 deletion predisposes to diabetes and steatosis via glucose-6-phosphatase and perilipin-5 upregulation.

Authors:
Christine Bernsmeier Michael T Dill Angela Provenzano Zuzanna Makowska Ilona Krol Giovanna Muscogiuri David Semela Luigi Tornillo Fabio Marra Markus H Heim François H T Duong

Lab Invest 2016 09 18;96(9):972-80. Epub 2016 Jul 18.

Hepatology Laboratory, Department of Biomedicine, University and University Hospital Basel, Basel, Switzerland.

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September 2016

The RSPO-LGR4/5-ZNRF3/RNF43 module controls liver zonation and size.

Authors:
Lara Planas-Paz Vanessa Orsini Luke Boulter Diego Calabrese Monika Pikiolek Florian Nigsch Yang Xie Guglielmo Roma Adriana Donovan Patricia Marti Nicolau Beckmann Michael T Dill Walter Carbone Sebastian Bergling Andrea Isken Matthias Mueller Bernd Kinzel Yi Yang Xiaohong Mao Thomas B Nicholson Raffaella Zamponi Paola Capodieci Reginald Valdez Daniel Rivera Andreas Loew Chinweike Ukomadu Luigi M Terracciano Tewis Bouwmeester Feng Cong Markus H Heim Stuart J Forbes Heinz Ruffner Jan S Tchorz

Nat Cell Biol 2016 05 18;18(5):467-79. Epub 2016 Apr 18.

Novartis Institutes for BioMedical Research, Novartis Pharma AG, 4056 Basel, Switzerland.

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May 2016

YAP promotes proliferation, chemoresistance, and angiogenesis in human cholangiocarcinoma through TEAD transcription factors.

Authors:
Patricia Marti Claudia Stein Tanja Blumer Yann Abraham Michael T Dill Monika Pikiolek Vanessa Orsini Giorgia Jurisic Philippe Megel Zuzanna Makowska Claudia Agarinis Luigi Tornillo Tewis Bouwmeester Heinz Ruffner Andreas Bauer Christian N Parker Tobias Schmelzle Luigi M Terracciano Markus H Heim Jan S Tchorz

Hepatology 2015 Nov 25;62(5):1497-510. Epub 2015 Aug 25.

Novartis Institutes for Biomedical Research, Developmental and Molecular Pathways, Novartis Pharma AG, Basel, Switzerland.

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November 2015

An intrahepatic transcriptional signature of enhanced immune activity predicts response to peginterferon in chronic hepatitis B.

Authors:
Louis Jansen Annikki de Niet Zuzanna Makowska Michael T Dill Karel A van Dort Valeska Terpstra R Bart Takkenberg Harry L A Janssen Markus H Heim Neeltje A Kootstra Hendrik W Reesink

Liver Int 2015 Jul 21;35(7):1824-32. Epub 2015 Jan 21.

Department of Gastroenterology and Hepatology, Academic Medical Center (AMC), University of Amsterdam (UvA), Amsterdam, The Netherlands.

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July 2015

Generation of a murine hepatic angiosarcoma cell line and reproducible mouse tumor model.

Authors:
Sonja Rothweiler Michael T Dill Luigi Terracciano Zuzanna Makowska Luca Quagliata Ruslan Hlushchuk Valentin Djonov Markus H Heim David Semela

Lab Invest 2015 Mar 24;95(3):351-62. Epub 2014 Nov 24.

1] Department of Biomedicine, University Basel, Basel, Switzerland [2] Division of Gastroenterology and Hepatology, Kantonsspital St. Gallen, St. Gallen, Switzerland.

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March 2015

Pegylated IFN-α regulates hepatic gene expression through transient Jak/STAT activation.

Authors:
Michael T Dill Zuzanna Makowska Gaia Trincucci Andreas J Gruber Julia E Vogt Magdalena Filipowicz Diego Calabrese Ilona Krol Daryl T Lau Luigi Terracciano Erik van Nimwegen Volker Roth Markus H Heim

J Clin Invest 2014 Apr 24;124(4):1568-81. Epub 2014 Feb 24.

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April 2014

Simultaneous detection of hepatitis C virus and interferon stimulated gene expression in infected human liver.

Authors:
Stefan Wieland Zuzanna Makowska Benedetta Campana Diego Calabrese Michael T Dill Josan Chung Francis V Chisari Markus H Heim

Hepatology 2014 Jun 25;59(6):2121-30. Epub 2014 Apr 25.

Department of Immunology and Microbial Science, Scripps Research Institute, La Jolla, CA.

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June 2014

Quantitative proteomics identifies the membrane-associated peroxidase GPx8 as a cellular substrate of the hepatitis C virus NS3-4A protease.

Authors:
Kenichi Morikawa Jérôme Gouttenoire Céline Hernandez Viet Loan Dao Thi Huong T L Tran Christian M Lange Michael T Dill Markus H Heim Olivier Donzé François Penin Manfredo Quadroni Darius Moradpour

Hepatology 2014 Feb 18;59(2):423-33. Epub 2013 Dec 18.

From the Division of Gastroenterology and Hepatology, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland.

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February 2014

Protein phosphatase 2A promotes hepatocellular carcinogenesis in the diethylnitrosamine mouse model through inhibition of p53.

Authors:
François H T Duong Michael T Dill Matthias S Matter Zuzanna Makowska Diego Calabrese Tanja Dietsche Sylvia Ketterer Luigi Terracciano Markus H Heim

Carcinogenesis 2014 Jan 29;35(1):114-22. Epub 2013 Jul 29.

Department of Biomedicine and.

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January 2014

Cell entry, efficient RNA replication, and production of infectious hepatitis C virus progeny in mouse liver-derived cells.

Authors:
Anne Frentzen Anggakusuma Engin Gürlevik Kathrin Hueging Sarah Knocke Corinne Ginkel Richard J P Brown Markus Heim Michael T Dill Andrea Kröger Ulrich Kalinke Lars Kaderali Florian Kuehnel Thomas Pietschmann

Hepatology 2014 Jan 18;59(1):78-88. Epub 2013 Nov 18.

Institute of Experimental Virology, TWINCORE, Centre for Experimental and Clinical Infection Research, a joint venture between the Helmholtz Centre for Infection Research and the Hannover Medical School, Hannover, Germany.

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January 2014

Downregulation of the endothelial genes Notch1 and ephrinB2 in patients with nodular regenerative hyperplasia.

Authors:
Sonja Rothweiler Luigi Terracciano Luigi Tornillo Michael T Dill Markus H Heim David Semela

Liver Int 2014 Apr 21;34(4):594-603. Epub 2013 Jul 21.

Department of Biomedicine, University Hospital Basel, University Basel, Basel, Switzerland.

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April 2014

Isolate-dependent use of claudins for cell entry by hepatitis C virus.

Authors:
Sibylle Haid Christina Grethe Michael T Dill Markus Heim Lars Kaderali Thomas Pietschmann

Hepatology 2014 Jan;59(1):24-34

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January 2014

Impact of genetic SLC28 transporter and ITPA variants on ribavirin serum level, hemoglobin drop and therapeutic response in patients with HCV infection.

Authors:
Monika Rau Felix Stickel Stefan Russmann Christine N Manser Philip P Becker Michael Weisskopf Johannes Schmitt Michael T Dill Jean-François Dufour Darius Moradpour David Semela Beat Müllhaupt Andreas Geier

J Hepatol 2013 Apr 27;58(4):669-75. Epub 2012 Nov 27.

Department of Gastroenterology and Hepatology, University Hospital Zurich, Zurich, Switzerland.

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April 2013