Michael Seminerio

Michael Seminerio

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Michael Seminerio

Michael Seminerio

Publications by authors named "Michael Seminerio"

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Benzimidazolone-based selective σ receptor ligands: Synthesis and pharmacological evaluation.

Eur J Med Chem 2019 Mar 9;165:250-257. Epub 2019 Jan 9.

Department of Medicinal Chemistry, College of Pharmacy, University of Florida, Gainesville, FL, 32610, USA; Department of Medicinal Chemistry, School of Pharmacy, The University of Mississippi, University, Mississippi, 38677, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ejmech.2019.01.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6369001PMC
March 2019

In vitro glucuronidation of aprepitant: a moderate inhibitor of UGT2B7.

Xenobiotica 2015 8;45(11):990-8. Epub 2015 Jun 8.

a Department of Medicine , University of Chicago , Chicago , IL , USA.

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http://dx.doi.org/10.3109/00498254.2015.1038743DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4844176PMC
June 2016

Methamphetamine-induced toxicity: an updated review on issues related to hyperthermia.

Pharmacol Ther 2014 Oct 14;144(1):28-40. Epub 2014 May 14.

Centers for Disease Control and Prevention, National Institute for Occupational Safety and Health, Morgantown, WV 26505, USA.

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http://dx.doi.org/10.1016/j.pharmthera.2014.05.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4700537PMC
October 2014

σ Receptor antagonist attenuation of methamphetamine-induced neurotoxicity is correlated to body temperature modulation.

Pharmacol Rep 2013 ;65(2):343-9

Department of Basic Pharmaceutical Sciences, School of Pharmacy, West Virginia University, 1 Medical Center Drive, West Virginia University Health Sciences Center, Morgantown, WV 26506, USA.

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February 2014

Evaluation of utility of pharmacokinetic studies in phase I trials of two oncology drugs.

Clin Cancer Res 2013 Nov 20;19(21):6039-43. Epub 2013 Sep 20.

Authors' Affiliations: Departments of Medicine, Committee on Clinical Pharmacology and Pharmacogenomics, Comprehensive Cancer Center, The University of Chicago, Chicago, Illinois.

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http://dx.doi.org/10.1158/1078-0432.CCR-13-0597DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3832109PMC
November 2013

Effect of ring-constrained phenylpropyloxyethylamines on sigma receptors.

Bioorg Med Chem 2013 Sep 11;21(17):4923-7. Epub 2013 Jul 11.

Department of Pharmaceutical Sciences, University of Maryland, School of Pharmacy, 20 N. Pine Street, Baltimore, MD 21201, USA.

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http://dx.doi.org/10.1016/j.bmc.2013.06.068DOI Listing
September 2013

Pharmacological evaluation of SN79, a sigma (σ) receptor ligand, against methamphetamine-induced neurotoxicity in vivo.

Eur Neuropsychopharmacol 2013 Aug 24;23(8):960-71. Epub 2012 Aug 24.

Department of Basic Pharmaceutical Sciences, School of Pharmacy, West Virginia University, PO Box 9500, Morgantown, WV 26506, USA.

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http://dx.doi.org/10.1016/j.euroneuro.2012.08.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3748261PMC
August 2013

Unmet needs in preventing adverse drug-drug interactions.

Clin Adv Hematol Oncol 2013 Aug;11(8):520-1

Postdoctoral Fellow Committee on Clinical Pharmacology and Pharmacogenomics The University of Chicago Chicago, Illinois.

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August 2013

The evaluation of AZ66, an optimized sigma receptor antagonist, against methamphetamine-induced dopaminergic neurotoxicity and memory impairment in mice.

Int J Neuropsychopharmacol 2013 Jun 29;16(5):1033-44. Epub 2012 Aug 29.

Department of Basic Pharmaceutical Sciences, School of Pharmacy, West Virginia University, Morgantown, WV 26506, USA.

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http://dx.doi.org/10.1017/S1461145712000831DOI Listing
June 2013

In vitro evaluation of guanidine analogs as sigma receptor ligands for potential anti-stroke therapeutics.

J Pharmacol Exp Ther 2013 Jan 12;344(1):155-66. Epub 2012 Oct 12.

Department of Molecular Pharmacology and Physiology, University of South Florida College of Medicine, 12901 Bruce B. Downs Blvd., MDC-9, Tampa, FL 33612-4799, USA.

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http://dx.doi.org/10.1124/jpet.112.199513DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3533416PMC
January 2013

Sigma-1 receptors: potential targets for the treatment of substance abuse.

Curr Pharm Des 2012 ;18(7):902-19

Department of Basic Pharmaceutical Sciences, School of Pharmacy, West Virginia University, Morgantown, WV 26506-9500, USA.

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http://dx.doi.org/10.2174/138161212799436601DOI Listing
September 2012

Effects of aging on behavioral assessment performance: implications for clinically relevant models of neurological disease.

J Neurosurg 2012 Sep 29;117(3):629-37. Epub 2012 Jun 29.

Department of Neurosurgery, West Virginia University, School of Medicine, Morgantown, West Virginia 26506-9183, USA.

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http://dx.doi.org/10.3171/2012.5.JNS112224DOI Listing
September 2012

Sigma receptor antagonists attenuate acute methamphetamine-induced hyperthermia by a mechanism independent of IL-1β mRNA expression in the hypothalamus.

Eur J Pharmacol 2012 Sep 20;691(1-3):103-9. Epub 2012 Jul 20.

Department of Basic Pharmaceutical Sciences, School of Pharmacy, West Virginia University, Morgantown, WV 26506, USA.

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http://dx.doi.org/10.1016/j.ejphar.2012.07.029DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3726051PMC
September 2012

Evaluation of sigma (σ) receptors in the antidepressant-like effects of ketamine in vitro and in vivo.

Eur Neuropsychopharmacol 2012 Apr 10;22(4):308-17. Epub 2011 Sep 10.

Department of Basic Pharmaceutical Sciences, West Virginia University, Morgantown, WV 26506, USA.

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http://dx.doi.org/10.1016/j.euroneuro.2011.08.002DOI Listing
April 2012

CM156, a high affinity sigma ligand, attenuates the stimulant and neurotoxic effects of methamphetamine in mice.

Neuropharmacology 2011 Oct-Nov;61(5-6):992-1000. Epub 2011 Jul 7.

Department of Basic Pharmaceutical Sciences, School of Pharmacy, West Virginia University, Morgantown, WV 26506, USA.

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http://dx.doi.org/10.1016/j.neuropharm.2011.06.028DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3615888PMC
February 2012

Synthesis and pharmacological evaluation of indole-based sigma receptor ligands.

Eur J Med Chem 2011 Oct 29;46(10):5154-61. Epub 2011 Aug 29.

Department of Medicinal Chemistry, School of Pharmacy, The University of Mississippi, University, MS 38677, USA.

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http://dx.doi.org/10.1016/j.ejmech.2011.08.031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3272488PMC
October 2011

Sigma (σ) receptor ligand, AC927 (N-phenethylpiperidine oxalate), attenuates methamphetamine-induced hyperthermia and serotonin damage in mice.

Pharmacol Biochem Behav 2011 Mar 2;98(1):12-20. Epub 2010 Dec 2.

Department of Basic Pharmaceutical Sciences, School of Pharmacy, West Virginia University, Morgantown, WV 26506, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S009130571000361
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http://dx.doi.org/10.1016/j.pbb.2010.11.023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3726056PMC
March 2011

The effect of the pyridyl nitrogen position in pyridylpiperazine sigma ligands.

Bioorg Med Chem Lett 2010 Apr 1;20(8):2564-5. Epub 2010 Mar 1.

Department of Pharmaceutical Sciences, University of Maryland, School of Pharmacy, Baltimore, MD 21201, USA.

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http://dx.doi.org/10.1016/j.bmcl.2010.02.087DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3401592PMC
April 2010