Michael Schlossmacher

Michael Schlossmacher

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Michael Schlossmacher

Publications by authors named "Michael Schlossmacher"

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Canadian guideline for Parkinson disease.

CMAJ 2019 Sep;191(36):E989-E1004

The Ottawa Hospital, University of Ottawa Brain and Mind Research Institute (Grimes, Fitzpatrick, Schlossmacher, Mestre), Ottawa, Ont.; Parkinson Canada (Gordon), Toronto, Ont.; University of Alberta Hospital (Miyasaki), Edmonton, Alta.; Montreal Neurological Institute (Fon), McGill University, Montréal, Que.; University of Alberta (Suchowersky), Edmonton, Alta.; Royal University Hospital (Rajput), University of Saskatchewan, Saskatoon, Sask.; Montreal General Hospital (Lafontaine, Postuma), McGill University, Montréal, Que.; Pacific Parkinson's Research Centre, Djavad Mowafaghian Centre for Brain Health (Appel-Cresswell), University of British Columbia, Vancouver, BC; Toronto Western Hospital (Kalia, Zurowski, Fox), University of Toronto, Toronto, Ont.; Dalhousie University (Schoffer), Halifax, NS; University of Manitoba Rady Faculty of Health Sciences (Udow), Winnipeg, Man.; Knowledge Synthesis Group (Barbeau, Hutton), Ottawa Hospital Research Institute, Ottawa, Ont.

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http://dx.doi.org/10.1503/cmaj.181504DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733687PMC
September 2019

Ripk3 licenced protection against microbial infection in the absence of Caspase1-11 inflammasome.

Microbes Infect 2019 Aug 17. Epub 2019 Aug 17.

Department of Biochemistry, Microbiology and Immunology, University of Ottawa, Ottawa, ON, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.micinf.2019.08.002DOI Listing
August 2019

DMS as an orthogonal separation to LC/ESI/MS/MS for quantifying isomeric cerebrosides in plasma and cerebrospinal fluid.

J Lipid Res 2019 01 9;60(1):200-211. Epub 2018 Nov 9.

Neural Regeneration Laboratory and India Taylor Lipidomics Research Platform, Ottawa Institute of Systems Biology, Department of Biochemistry, Microbiology, and Immunology, University of Ottawa, Ottawa, Ontario, Canada

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http://dx.doi.org/10.1194/jlr.D089797DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6314254PMC
January 2019

Recommendations of the Global Multiple System Atrophy Research Roadmap Meeting.

Neurology 2018 01 13;90(2):74-82. Epub 2017 Dec 13.

From Muhammad Ali Parkinson Center (R.R.W.), Barrow Neurological Institute, Phoenix, AZ; Department of Neurology (F.K., G.K.W., W.P., K.S., N.S.), Medical University Innsbruck, Austria; National Institute of Neurological Disorders and Stroke (W.R.G., W.J.K.), NIH, Bethesda, MD; Department of Neurology (P.A.L.), Mayo Clinic, Rochester, MN; Brain and Mind Centre (G.H.), Sydney Medical School, the University of Sydney; UNSW Medicine & Neuroscience Research Australia (G.H.), Sydney; Queen Square Brain Bank (J.H.), UCL Institute of Neurology (N.P.Q.), London, UK; UPS, INSERM, and CHU de Toulouse (O.R.), University de Toulouse; Centre de Référence Maladie Rare contre l'AMS (O.R.), Centre d'Investigation Clinique CIC1436, Départments de Pharmacologie Clinique et de Neurosciences, NeuroToul/COEN Center of Excellence in Neurodegeneration, Toulouse, France; Department of Pathology & Laboratory Medicine (L.M.S.), Perelman School of Medicine, University of Pennsylvania, Philadelphia; Center for Neurosciences (D.E.), The Feinstein Institute for Medical Research, Manhasset, NY; The Multiple System Atrophy (MSA) Coalition, Inc. (P. B., J.B., P.F., L.K., C.L., C.R., S.S.), Charlotte, NC; Cleveland Clinic Lou Ruvo Center for Brain Health (J.L.C.), Las Vegas, NV; Medical Affairs (V.A.), Teva Pharmaceuticals, Frazer, PA; Department of Neurology (G.B.), David Geffen School of Medicine, Brain Research Institute, and Molecular Biology Institute, University of California at Los Angeles; Institute of Neurology (D.J.B.), University of Newcastle upon Tyne, UK; Van Andel Research Institute (P. Brundin), Center for Neurodegenerative Science, Grand Rapids, MI; Center for Neurological Restoration (H.F.), Cleveland Clinic, OH; Defeat MSA (P.F.); MSA Shoe Charity (P.F., C.R.), Saint Clair Shores, MI; Department of Neurology (R.F.), Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA; Department of Neurodegenerative Diseases (T.G.), Hertie Institute of Clinical Brain Research, University of Tübingen; German Center for Neurodegenerative Diseases (DZNE) (T.G.), Tübingen, Germany; Lundbeck LLC (A.H.), Deerfield, IL; German Center for Neurodegenerative Diseases (DZNE) (G.U.H.), Munich; Department of Neurology (G.U.H.), Technical University of Munich, Germany; Neurogenomics Division (M.J.H.), The Translational Genomics Research Institute, Phoenix, AZ; Dandrite & Department of Biomedicine (P.H.J.), Aarhus University, Denmark; Quanterix (A.J.), Lexington, MA; Department of Neurology (U.J.K.), Columbia University Medical Center; Department of Neurology (H.K.), New York University School of Medicine, New York; Whitehead Institute for Biomedical Research (V.K.), Cambridge; Ann Romney Center for Neurologic Disease (V.K.), Department of Neurology, Brigham and Women's Hospital and Harvard Medical School, Boston; Harvard Stem Cell Institute (V.K.), Cambridge, MA; Department of Neurology (T.K.), University of Bonn; German Center for Neurodegenerative Diseases (DZNE) (T.K.), Bonn, Germany; Brain and Mind Centre (W.S.K.), Sydney Medical School, University of Sydney, Australia; Department of Neurology (P.L.), Henry Ford Hospital; Department of Neurology (P.L.), Wayne State University School of Medicine, Detroit, MI; Division of Neurosciences (E.M.), National Institute on Aging/NIH, Bethesda, MD; Centre de Référence Maladie Rare AMS (W.M.), Hôpital Pellegrin, CHU de Bordeaux; Université de Bordeaux (W.M.), Institut des Maladies Neurodégénératives, UMR 5293, Bordeaux; Paris Saclay Institute of Neuroscience (R.M.), CNRS, Gif-sur-Yvette, France; Genentech Inc. (S.O.), South San Francisco; Cedars-Sinai Medical Center (S.P.), Los Angeles, CA; Department of Neurology (D.R.), Vanderbilt University Medical Center, Nashville, TN; MSA NJ (C.R.), Howell, NJ; Prothena Biosciences (D.S.), South San Francisco, CA; Division of Neurology (M.S.), Department of Medicine, The Ottawa Hospital, Canada; Department of Neurology (J.D.S.), Massachusetts General Hospital, Harvard Medical School, Boston, MA; Cure MSA Foundation (L.S.), Fremont, CA; Avid Radiopharmaceuticals (A.S.), Philadelphia, PA; Department of Neurological Sciences (G.T.S.), Rush University Medical Center, Chicago, IL; Department of Neurology (S.T.), Graduate School of Medicine, Tokyo University, Tokyo, Japan; and University of Washington (J.Z.), Seattle. W.R.G. is currently affiliated with Janssen Research and Development, Titusville, NJ.

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http://dx.doi.org/10.1212/WNL.0000000000004798DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5772155PMC
January 2018

Modelling idiopathic Parkinson disease as a complex illness can inform incidence rate in healthy adults: the P EDIGT score.

Eur J Neurosci 2017 01 27;45(1):175-191. Epub 2016 Dec 27.

Neuroscience Program, Ottawa Hospital Research Institute, 451 Smyth Road, RGH #1414, Ottawa, ON, K1H 8M5, Canada.

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http://dx.doi.org/10.1111/ejn.13476DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5324667PMC
January 2017

Biological confounders for the values of cerebrospinal fluid proteins in Parkinson's disease and related disorders.

J Neurochem 2016 10 10;139 Suppl 1:290-317. Epub 2016 Feb 10.

Program in Neuroscience and Division of Neurology, The Ottawa Hospital, University of Ottawa Brain & Mind Research Institute, Ottawa, Ontario, Canada.

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http://dx.doi.org/10.1111/jnc.13390DOI Listing
October 2016

Protective effect of vagotomy suggests source organ for Parkinson disease.

Ann Neurol 2015 Nov 22;78(5):834-5. Epub 2015 Sep 22.

Ottawa Hospital Research Institute, Ottawa, Canada.

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http://doi.wiley.com/10.1002/ana.24501
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http://dx.doi.org/10.1002/ana.24501DOI Listing
November 2015

Association between α-synuclein blood transcripts and early, neuroimaging-supported Parkinson's disease.

Brain 2015 Sep 28;138(Pt 9):2659-71. Epub 2015 Jul 28.

1 Neurogenomics Lab and Parkinson Personalized Medicine Program, Harvard Medical School and Brigham and Women's Hospital, Cambridge, MA 02139, USA 2 Department of Neurology, Massachusetts General Hospital, Boston, MA 02114, USA 4 Ann Romney Centre for Neurologic Diseases, Brigham and Women's Hospital, Boston, MA 02115, USA 5 Biomarkers Program, Harvard NeuroDiscovery Center, Boston, MA 02115, USA 7 Department of Neurology, Brigham and Women's Hospital, Boston, MA 02115, USA

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http://dx.doi.org/10.1093/brain/awv202DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4643625PMC
September 2015

LRRK2 and Nod2 promote lysozyme sorting in Paneth cells.

Nat Immunol 2015 Sep;16(9):898-900

Department of Immunology, University of Toronto, Toronto, Canada.

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http://dx.doi.org/10.1038/ni.3255DOI Listing
September 2015

Fluid biomarkers in multiple system atrophy: A review of the MSA Biomarker Initiative.

Neurobiol Dis 2015 Aug 15;80:29-41. Epub 2015 May 15.

Service de Neurologie, CHU de Bordeaux, F-33076 Bordeaux, France; Centre de référence atrophie multisystématisée, CHU de Bordeaux, F-33076 Bordeaux, France; Univ. de Bordeaux, Institut des Maladies Neurodégénératives, UMR 5293, F-33076 Bordeaux, France; CNRS, Institut des Maladies Neurodégénératives, UMR 5293, F-33076 Bordeaux, France. Electronic address:

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http://dx.doi.org/10.1016/j.nbd.2015.05.004DOI Listing
August 2015

Alpha-synuclein in the appendiceal mucosa of neurologically intact subjects.

Mov Disord 2014 Jul 18;29(8):991-8. Epub 2013 Dec 18.

Centre for Cancer Therapeutics, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada; Department of Pathology and Laboratory Medicine, Faculty of Medicine, University of Ottawa, Ottawa, Ontario, Canada; Department of Biochemistry, Microbiology and Immunology, Faculty of Medicine, University of Ottawa, Ottawa, Ontario, Canada.

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http://dx.doi.org/10.1002/mds.25779DOI Listing
July 2014

Towards translational therapies for multiple system atrophy.

Prog Neurobiol 2014 Jul 2;118:19-35. Epub 2014 Mar 2.

Department of Neurology, Innsbruck Medical University, Anichstraße 35, Innsbruck 6020, Austria. Electronic address:

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http://dx.doi.org/10.1016/j.pneurobio.2014.02.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4068324PMC
July 2014

Nonmotor and diagnostic findings in subjects with de novo Parkinson disease of the DeNoPa cohort.

Neurology 2013 Oct 30;81(14):1226-34. Epub 2013 Aug 30.

From the Center of Parkinsonism and Movement Disorders (B.M., E.T., F.S.-D., T.W., J.E., M.S., E.L., C.T.), Paracelsus-Elena-Klinik, Kassel; Department of Neurosurgery (B.M., N.K.F., C.T.), University Medical Centre, Goettingen; Department of Psychology (E.T.), University Kassel; Section of Clinical and Molecular Neurogenetics at the Department of Neurology (K.R.K., K.L., C.K.), University of Luebeck; Departments of Neuropathology (B.M.) and Medical Statistics (T.F.), University Medical Centre, Goettingen, Germany; Program in Neuroscience (M.G.S.), Ottawa Hospital Research Institute; Division of Neurology, The Ottawa Hospital, University of Ottawa, Canada; and ReSearch Pharmaceutical Services (R.K.), Nuremberg, Germany.

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http://dx.doi.org/10.1212/WNL.0b013e3182a6cbd5DOI Listing
October 2013

Unrecognized vitamin D3 deficiency is common in Parkinson disease: Harvard Biomarker Study.

Neurology 2013 Oct 25;81(17):1531-7. Epub 2013 Sep 25.

From the Neurogenomics Laboratory (H.D., K.D., K.C.L., A.N.H., K.D., A.T.-L., C.R.S.), Harvard Medical School and Brigham & Women's Hospital, Cambridge; Biomarkers Program (K.D., K.C.L., A.N.H., K.D., A.T.-L., M.T.H., U.S.S., B.M., N.M., V.K., S.N.G., D.J.S., M.A.S., M.G.S., B.T.H., J.H.G., C.R.S.), Harvard NeuroDiscovery Center, Boston; Department of Neurology (J.J.L., U.S.S., A.-M.W., A.W.F., A.Y.H., N.M., V.K., S.N.G., M.A.S., B.T.H., J.H.G., C.R.S.), Massachusetts General Hospital, Boston; Department of Neurology (M.T.H., A.Y.H., D.J.S., L.R.S., C.R.S.), Brigham and Women's Hospital, Boston, MA; Paracelsus-Elena-Klinik (B.M.), Kassel, Germany; and Division of Neurology, the Ottawa Hospital, University of Ottawa (M.G.S.), Canada.

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http://dx.doi.org/10.1212/WNL.0b013e3182a95818DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3888173PMC
October 2013

Parkin-dependent degradation of the F-box protein Fbw7β promotes neuronal survival in response to oxidative stress by stabilizing Mcl-1.

Mol Cell Biol 2013 Sep 15;33(18):3627-43. Epub 2013 Jul 15.

Department of Cell and Molecular Biology, The Scripps Research Institute, La Jolla, California, USA.

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http://dx.doi.org/10.1128/MCB.00535-13DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3753862PMC
September 2013

Respiratory infection of mice with mammalian reoviruses causes systemic infection with age and strain dependent pneumonia and encephalitis.

Virol J 2013 Mar 1;10:67. Epub 2013 Mar 1.

Department of Biochemistry, Microbiology and Immunology, Faculty of Medicine, University of Ottawa, 451 Smyth Rd, Ottawa, Ontario K1H 8M5, Canada.

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http://virologyj.biomedcentral.com/articles/10.1186/1743-422
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http://dx.doi.org/10.1186/1743-422X-10-67DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3605257PMC
March 2013

Novel one-step immunoassays to quantify α-synuclein: applications for biomarker development and high-throughput screening.

J Biol Chem 2012 Sep 27;287(40):33691-705. Epub 2012 Jul 27.

Neuroscience Discovery Group, Novartis Institutes for Biomedical Research, Novartis Pharma AG, Basel, Switzerland.

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http://dx.doi.org/10.1074/jbc.M112.379792DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3460466PMC
September 2012

Mutant GBA1 expression and synucleinopathy risk: first insights from cellular and mouse models.

Neurodegener Dis 2012 9;10(1-4):195-202. Epub 2012 Feb 9.

Genzyme, Sanofi Company, Framingham, Mass 01701, USA.

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http://dx.doi.org/10.1159/000335038DOI Listing
August 2012

Considerations regarding the etiology and future treatment of autosomal recessive versus idiopathic Parkinson disease.

Curr Treat Options Neurol 2012 Jun;14(3):230-40

Division of Neurology, Department of Medicine, The Ottawa Hospital and Division of Neuroscience, Ottawa Hospital Research Institute, 451 Smyth Road, Roger Guindon Hall #1412, Ottawa, ON, Canada, K1H 8M5.

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http://dx.doi.org/10.1007/s11940-012-0175-8DOI Listing
June 2012

Development of electrochemiluminescence-based singleplex and multiplex assays for the quantification of α-synuclein and other proteins in cerebrospinal fluid.

Methods 2012 Apr 23;56(4):514-8. Epub 2012 Mar 23.

Institute for Neuropathology, Prion and Dementia Research Unit, University Medical Center Göttingen, Robert-Koch-Str. 40, 37075 Goettingen, Germany.

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http://dx.doi.org/10.1016/j.ymeth.2012.03.016DOI Listing
April 2012

Translational research in neurology and neuroscience 2011: movement disorders.

Arch Neurol 2011 Jun 14;68(6):709-16. Epub 2011 Feb 14.

Section of Clinical and Molecular Neurogenetics, Department of Neurology, University of Lübeck, Lübeck, Germany.

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http://dx.doi.org/10.1001/archneurol.2011.11DOI Listing
June 2011

Biomarker research in Parkinson's disease: objective measures needed for patient stratification in future cause-directed trials.

Biomark Med 2010 Oct;4(5):647-50

Division of Neuroscience-OHRI, University of Ottawa, 451 Smyth Road, RGH #1412, Ottawa, ON, K1H 8M5, Canada.

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http://dx.doi.org/10.2217/bmm.10.93DOI Listing
October 2010

CSF synuclein: adding to the biomarker footprint of dementia with Lewy bodies.

J Neurol Neurosurg Psychiatry 2010 Jun;81(6):590-1

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http://dx.doi.org/10.1136/jnnp.2010.206391DOI Listing
June 2010

Cathepsin D expression level affects alpha-synuclein processing, aggregation, and toxicity in vivo.

Mol Brain 2009 Feb 9;2. Epub 2009 Feb 9.

Center for Neurologic Diseases, Department of Neurology, Brigham & Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1186/1756-6606-2-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2644690PMC
February 2009

Increased DJ-1 expression under oxidative stress and in Alzheimer's disease brains.

Mol Neurodegener 2009 Feb 25;4:12. Epub 2009 Feb 25.

Center for Neurologic Diseases, Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, Harvard University, Boston, MA 02115, USA.

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http://dx.doi.org/10.1186/1750-1326-4-12DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2654450PMC
February 2009

Multiple system atrophy: a primary oligodendrogliopathy.

Ann Neurol 2008 Sep;64(3):239-46

Department of Neurology, Innsbruck Medical University, Innsbruck, Austria.

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http://dx.doi.org/10.1002/ana.21465DOI Listing
September 2008

GATA transcription factors directly regulate the Parkinson's disease-linked gene alpha-synuclein.

Proc Natl Acad Sci U S A 2008 Aug 31;105(31):10907-12. Epub 2008 Jul 31.

Center for Neurologic Diseases, Harvard Medical School and Brigham and Women's Hospital, Cambridge, MA 02139, USA.

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http://dx.doi.org/10.1073/pnas.0802437105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2504800PMC
August 2008

The effects of oxidative stress on parkin and other E3 ligases.

J Neurochem 2007 Dec 19;103(6):2354-68. Epub 2007 Sep 19.

Center for Neurologic Diseases, Department of Neurology, Brigham and Women's Hospital, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1111/j.1471-4159.2007.04911.xDOI Listing
December 2007

Parkinson disease, 10 years after its genetic revolution: multiple clues to a complex disorder.

Neurology 2007 Nov 29;69(22):2093-104. Epub 2007 Aug 29.

Department of Neurology, University of Lübeck, Ratzeburger Allee 160, 23538 Lübeck, Germany.

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http://dx.doi.org/10.1212/01.wnl.0000271880.27321.a7DOI Listing
November 2007

Serum heart-type fatty acid-binding protein and cerebrospinal fluid tau: marker candidates for dementia with Lewy bodies.

Neurodegener Dis 2007 6;4(5):366-75. Epub 2007 Jul 6.

Center for Neurologic Diseases, Brigham and Women's Hospital, Harvard Institutes of Medicine, 77 Avenue Louis Pasteur, Boston, MA 02115, USA.

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http://dx.doi.org/10.1159/000105157DOI Listing
October 2007

Deciphering the role of heterozygous mutations in genes associated with parkinsonism.

Lancet Neurol 2007 Jul;6(7):652-62

Department of Neurology, University of Lübeck, Lübeck, Germany.

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http://dx.doi.org/10.1016/S1474-4422(07)70174-6DOI Listing
July 2007

Aggregated alpha-synuclein mediates dopaminergic neurotoxicity in vivo.

J Neurosci 2007 Mar;27(12):3338-46

Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA.

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http://dx.doi.org/10.1523/JNEUROSCI.0285-07.2007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6672466PMC
March 2007

Structure of acid beta-glucosidase with pharmacological chaperone provides insight into Gaucher disease.

Nat Chem Biol 2007 Feb 24;3(2):101-7. Epub 2006 Dec 24.

Structural Neurology Lab, Brigham and Women's Hospital and Harvard Medical School, 77 Ave Louis Pasteur, Boston, Massachusetts 02115, USA.

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http://dx.doi.org/10.1038/nchembio850DOI Listing
February 2007

Molecular markers of early Parkinson's disease based on gene expression in blood.

Proc Natl Acad Sci U S A 2007 Jan 10;104(3):955-60. Epub 2007 Jan 10.

Center for Neurologic Diseases, Brigham and Women's Hospital and Harvard Medical School, 65 Landsdowne Street, Cambridge, MA 02139, USA.

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http://dx.doi.org/10.1073/pnas.0610204104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1766335PMC
January 2007

Decreased alpha-synuclein in cerebrospinal fluid of aged individuals and subjects with Parkinson's disease.

Biochem Biophys Res Commun 2006 Oct 14;349(1):162-6. Epub 2006 Aug 14.

Department of Neurology, Kyoto Prefectural University of Medicine, Kyoto 602-0841, Japan, and Center for Neurologic Diseases, Brigham and Women's Hospital, Boston, MA 02115, USA.

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http://dx.doi.org/10.1016/j.bbrc.2006.08.024DOI Listing
October 2006

Parkin protects against mitochondrial toxins and beta-amyloid accumulation in skeletal muscle cells.

J Biol Chem 2006 May 3;281(18):12809-16. Epub 2006 Mar 3.

Department of Neurology, Caritas St. Elizabeth's Medical Center, Tufts University School of Medicine, Boston, Massachusetts 02135, USA.

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http://dx.doi.org/10.1074/jbc.M512649200DOI Listing
May 2006

Detection of oligomeric forms of alpha-synuclein protein in human plasma as a potential biomarker for Parkinson's disease.

FASEB J 2006 Mar;20(3):419-25

Department of Biochemistry, Faculty of Medicine and Health Science, United Arab Emirates University, Al Ain P. O. Box 17666, United Arab Emirates.

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http://dx.doi.org/10.1096/fj.03-1449comDOI Listing
March 2006

The genetics of Parkinson disease: Implications for neurological care.

Nat Clin Pract Neurol 2006 Mar;2(3):136-46

Department of Neurology, Lübeck University, Lübeck, Germany.

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http://dx.doi.org/10.1038/ncpneuro0126DOI Listing
March 2006

Synphilin-1 and parkin show overlapping expression patterns in human brain and form aggresomes in response to proteasomal inhibition.

Neurobiol Dis 2005 Nov;20(2):401-11

Reta Lila Weston Institute of Neurological Studies, Royal Free and UCL Medical School, The Windeyer Building, 46 Cleveland Street, London W1T 4JF, UK.

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http://dx.doi.org/10.1016/j.nbd.2005.03.021DOI Listing
November 2005

Dopamine covalently modifies and functionally inactivates parkin.

Nat Med 2005 Nov 16;11(11):1214-21. Epub 2005 Oct 16.

Center for Neurologic Diseases, Department of Neurology, Brigham and Women's Hospital, 77 Avenue Louis Pasteur, HIM 7th Floor, Boston, Massachusetts 02115, USA.

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http://dx.doi.org/10.1038/nm1314DOI Listing
November 2005

Parkinson's disease: assays for the ubiquitin ligase activity of neural Parkin.

Methods Mol Biol 2005 ;301:351-69

Center for Neurologic Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1385/1-59259-895-1:351DOI Listing
June 2005

The glucocerebrosidase gene and Parkinson's disease in Ashkenazi Jews.

N Engl J Med 2005 Feb;352(7):728-31; author reply 728-31

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February 2005

Dimerization of Parkinson's disease-causing DJ-1 and formation of high molecular weight complexes in human brain.

Mol Cell Neurosci 2004 Nov;27(3):236-46

Center for Neurologic Diseases, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA.

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http://dx.doi.org/10.1016/j.mcn.2004.06.014DOI Listing
November 2004

RING finger 1 mutations in Parkin produce altered localization of the protein.

Hum Mol Genet 2003 Nov 30;12(22):2957-65. Epub 2003 Sep 30.

Laboratory of Neurogenetics, National Institute on Aging, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1093/hmg/ddg328DOI Listing
November 2003

Seizures after epidural blood patch.

Reg Anesth Pain Med 2003 Jan-Feb;28(1):71; author reply 71-2

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May 2003