Michael Ristow

Michael Ristow

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Michael Ristow

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Redox-mediated regulation of aging and healthspan by an evolutionarily conserved transcription factor HLH-2/Tcf3/E2A.

Redox Biol 2020 May 4;32:101448. Epub 2020 Feb 4.

Energy Metabolism Laboratory, Institute of Translational Medicine, Department of Health Sciences and Technology, Swiss Federal Institute of Technology (ETH) Zurich, Schwerzenbach, CH-8603, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.redox.2020.101448DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7096751PMC
May 2020

Endogenous metabolites promote stress resistance through induction of mitohormesis.

EMBO Rep 2020 May 23;21(5):e50340. Epub 2020 Apr 23.

Energy Metabolism Laboratory, Department of Health Sciences and Technology, Institute of Translational Medicine, Swiss Federal Institute of Technology (ETH) Zurich, Schwerzenbach, Switzerland.

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http://dx.doi.org/10.15252/embr.202050340DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7202198PMC
May 2020

Partial impairment of insulin receptor expression mimics fasting to prevent diet-induced fatty liver disease.

Nat Commun 2020 Apr 29;11(1):2080. Epub 2020 Apr 29.

Energy Metabolism Laboratory, Institute of Translational Medicine, Department of Health Sciences and Technology, Swiss Federal Institute of Technology (ETH), Zürich, Switzerland.

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http://dx.doi.org/10.1038/s41467-020-15623-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7190665PMC
April 2020

Deficiency in ROS-sensing nuclear factor erythroid 2-like 2 causes altered glucose and lipid homeostasis following exercise training.

Am J Physiol Cell Physiol 2020 02 27;318(2):C337-C345. Epub 2019 Nov 27.

Energy Metabolism Laboratory, Institute for Translational Medicines, Department of Health Sciences and Technology, Swiss Federal Institute of Technology Zurich, Schwerzenbach, Switzerland.

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http://dx.doi.org/10.1152/ajpcell.00426.2019DOI Listing
February 2020

Impairing L-Threonine Catabolism Promotes Healthspan through Methylglyoxal-Mediated Proteohormesis.

Cell Metab 2018 04 15;27(4):914-925.e5. Epub 2018 Mar 15.

Energy Metabolism Laboratory, Institute of Translational Medicine, D-HEST, Swiss Federal Institute of Technology (ETH) Zürich, Schwerzenbach 8603, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.cmet.2018.02.004DOI Listing
April 2018

Animal models of obesity and diabetes mellitus.

Nat Rev Endocrinol 2018 03 19;14(3):140-162. Epub 2018 Jan 19.

Institute for Diabetes and Obesity, Helmholtz Diabetes Center at Helmholtz Zentrum München, German Research Center for Environmental Health (GmbH), Ingolstädter Landstr. 1, D-85764 Neuherberg, Germany.

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http://dx.doi.org/10.1038/nrendo.2017.161DOI Listing
March 2018

Dietary Carbohydrates Impair Healthspan and Promote Mortality.

Cell Metab 2017 Oct;26(4):585-587

Energy Metabolism Laboratory, Institute of Translational Medicine, Swiss Federal Institute of Technology (ETH) Zurich, Zurich-Schwerzenbach 8603, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.cmet.2017.09.011DOI Listing
October 2017

Lipid and Carbohydrate Metabolism in .

Genetics 2017 10;207(2):413-446

Energy Metabolism Laboratory, Institute of Translational Medicine, Department of Health Sciences and Technology, Swiss Federal Institute of Technology Zurich, 8603 Schwerzenbach-Zurich, Switzerland.

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http://dx.doi.org/10.1534/genetics.117.300106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5629314PMC
October 2017

Impairment of insulin signalling in peripheral tissue fails to extend murine lifespan.

Aging Cell 2017 08 22;16(4):761-772. Epub 2017 May 22.

Energy Metabolism Laboratory, Swiss Federal Institute of Technology (ETH) Zurich-Schwerzenbach, Schwerzenbach, Zurich, Switzerland.

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http://dx.doi.org/10.1111/acel.12610DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5506415PMC
August 2017

Non-linear impact of glutathione depletion on C. elegans life span and stress resistance.

Redox Biol 2017 04 6;11:502-515. Epub 2016 Dec 6.

Institute of Nutrition, Department of Nutrigenomics, Friedrich-Schiller-Universität Jena, D-07743 Jena, Germany. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S22132317163020
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http://dx.doi.org/10.1016/j.redox.2016.12.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5228094PMC
April 2017

Lifespan effects of mitochondrial mutations.

Nature 2016 12;540(7633):E13-E14

Lübeck Institute of Experimental Dermatology, University of Lübeck, Germany.

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http://dx.doi.org/10.1038/nature20778DOI Listing
December 2016

Insulin-IGF signaling affects cell transformation in the BALB/c 3T3 cell model.

Sci Rep 2016 11 16;6:37120. Epub 2016 Nov 16.

Institute of Nutrition, Friedrich Schiller University Jena, Dornburger Str. 24, 07743 Jena, Germany.

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http://dx.doi.org/10.1038/srep37120DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5111065PMC
November 2016

Do antioxidant supplements interfere with skeletal muscle adaptation to exercise training?

J Physiol 2016 09 18;594(18):5135-47. Epub 2016 Jan 18.

Energy Metabolism Laboratory, Swiss Federal Institute of Technology (ETH), 8603, Zurich, Switzerland.

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http://dx.doi.org/10.1113/JP270654DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5023714PMC
September 2016

Mitohormesis in exercise training.

Free Radic Biol Med 2016 09 30;98:123-130. Epub 2015 Nov 30.

Energy Metabolism Laboratory, Swiss Federal Institute of Technology (ETH), 8603 Zurich, Switzerland.

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http://dx.doi.org/10.1016/j.freeradbiomed.2015.11.032DOI Listing
September 2016

Nuclear factor erythroid-derived 2-like 2 (NFE2L2, Nrf2) mediates exercise-induced mitochondrial biogenesis and the anti-oxidant response in mice.

J Physiol 2016 09 27;594(18):5195-207. Epub 2016 May 27.

Energy Metabolism Laboratory, Swiss Federal Institute of Technology (ETH) Zurich, Schwerzenbach, Switzerland.

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http://dx.doi.org/10.1113/JP271957DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5023720PMC
September 2016

Opposing Effects of Antidiabetic Interventions on Malignant Growth and Metastasis.

Cell Metab 2016 06;23(6):959-960

Department of Health Sciences and Technology, Swiss Federal Institute of Technology Zurich (ETHZ), 8092 Zurich, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.cmet.2016.05.017DOI Listing
June 2016

Time-resolved functional analysis of acute impairment of frataxin expression in an inducible cell model of Friedreich ataxia.

Biol Open 2016 May 15;5(5):654-61. Epub 2016 May 15.

Institute of Nutrition, Friedrich Schiller University (FSU) Jena, Dornburgerstraße 24, Jena D-07743, Germany

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http://dx.doi.org/10.1242/bio.017004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4874353PMC
May 2016

A Genome-Scale Database and Reconstruction of Caenorhabditis elegans Metabolism.

Cell Syst 2016 05 19;2(5):312-22. Epub 2016 May 19.

Research Group Medical Systems Biology, Christian-Albrechts-University Kiel, 24105 Kiel, Germany; Research Group Theoretical Systems Biology, Friedrich Schiller-University (FSU) Jena, 07745 Jena, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.cels.2016.04.017DOI Listing
May 2016

MicroRNA-29a in Adult Muscle Stem Cells Controls Skeletal Muscle Regeneration During Injury and Exercise Downstream of Fibroblast Growth Factor-2.

Stem Cells 2016 Mar 29;34(3):768-80. Epub 2016 Jan 29.

Division of Endocrinology, Diabetes, and Clinical Nutrition, University Zurich and University Hospital Zurich, Zurich, Switzerland.

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http://dx.doi.org/10.1002/stem.2281DOI Listing
March 2016

Longitudinal RNA-Seq Analysis of Vertebrate Aging Identifies Mitochondrial Complex I as a Small-Molecule-Sensitive Modifier of Lifespan.

Cell Syst 2016 02 24;2(2):122-32. Epub 2016 Feb 24.

Leibniz Institute on Aging-Fritz Lipmann Institute (FLI), Beutenbergstraße 11, 07745 Jena, Germany; Scuola Normale Superiore, Laboratory of Biology, c/o Istituto di Biofisica del CNR, via Moruzzi 1, 56124 Pisa, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.cels.2016.01.014DOI Listing
February 2016

A mitochondrially encoded hormone ameliorates obesity and insulin resistance.

Cell Metab 2015 Mar;21(3):355-6

Energy Metabolism Laboratory, Swiss Federal Institute of Technology (ETH), 8603 Zurich, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.cmet.2015.02.013DOI Listing
March 2015

Insulin and insulin-like growth factor 1 receptors are required for normal expression of imprinted genes.

Proc Natl Acad Sci U S A 2014 Oct 22;111(40):14512-7. Epub 2014 Sep 22.

Section on Integrative Physiology and Metabolism, Joslin Diabetes Center and Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02215;

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http://dx.doi.org/10.1073/pnas.1415475111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4209990PMC
October 2014

Extension of life span by impaired glucose metabolism in Caenorhabditis elegans is accompanied by structural rearrangements of the transcriptomic network.

PLoS One 2013 30;8(10):e77776. Epub 2013 Oct 30.

Systems Biology and Bioinformatics Group, Leibniz Institute for Natural Product Research and Infection Biology - Hans-Knoell-Institute, Jena, Germany.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0077776PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3813781PMC
September 2014

Unraveling the truth about antioxidants: mitohormesis explains ROS-induced health benefits.

Authors:
Michael Ristow

Nat Med 2014 Jul;20(7):709-11

Energy Metabolism Laboratory, ETH Zurich, Schwerzenbach-Zurich, Switzerland.

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http://dx.doi.org/10.1038/nm.3624DOI Listing
July 2014

Gender-specific impact of personal health parameters on individual brain aging in cognitively unimpaired elderly subjects.

Front Aging Neurosci 2014 23;6:94. Epub 2014 May 23.

Structural Brain Mapping Group, Department of Psychiatry, Jena University Hospital Jena, Germany ; Department of Neurology, Jena University Hospital Jena, Germany.

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http://dx.doi.org/10.3389/fnagi.2014.00094DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4033192PMC
June 2014

Mitohormesis: Promoting Health and Lifespan by Increased Levels of Reactive Oxygen Species (ROS).

Dose Response 2014 May 31;12(2):288-341. Epub 2014 Jan 31.

Dept. of Human Nutrition, Institute of Nutrition, University of Jena, Jena D-07743, Germany.

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http://dx.doi.org/10.2203/dose-response.13-035.RistowDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4036400PMC
May 2014

Pathogenesis of human mitochondrial diseases is modulated by reduced activity of the ubiquitin/proteasome system.

Cell Metab 2014 Apr;19(4):642-52

Institute for Genetics and Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, Zülpicher Strasse 47a, 50674 Cologne, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.cmet.2014.01.016DOI Listing
April 2014

D-Glucosamine supplementation extends life span of nematodes and of ageing mice.

Nat Commun 2014 Apr 8;5:3563. Epub 2014 Apr 8.

1] Energy Metabolism Laboratory, ETH Zürich (Swiss Federal Institute of Technology Zurich), Zürich CH-8603, Switzerland [2] German Institute of Human Nutrition Potsdam-Rehbrücke, D-14558 Nuthetal, Germany [3] Department of Human Nutrition, Institute of Nutrition, University of Jena, D-07743 Jena, Germany.

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http://dx.doi.org/10.1038/ncomms4563DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3988823PMC
April 2014

Long-chain metabolites of α-tocopherol occur in human serum and inhibit macrophage foam cell formation in vitro.

Free Radic Biol Med 2014 Mar 1;68:43-51. Epub 2013 Dec 1.

Department of Human Nutrition, Institute of Nutrition, Friedrich Schiller University Jena, 07743 Jena, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.freeradbiomed.2013.11.009DOI Listing
March 2014

Neuronal ROS signaling rather than AMPK/sirtuin-mediated energy sensing links dietary restriction to lifespan extension.

Mol Metab 2013 14;2(2):92-102. Epub 2013 Feb 14.

Department of Human Nutrition, Institute of Nutrition, University of Jena, Jena D-07743, Germany ; Leibniz Graduate School of Aging, Leibniz Institute for Age Research, Fritz-Lipmann-Institute, Jena D-07745, Germany.

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https://linkinghub.elsevier.com/retrieve/pii/S22128778130002
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http://dx.doi.org/10.1016/j.molmet.2013.02.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3817383PMC
November 2013

A radical opposition in body weight control.

EMBO Mol Med 2013 Aug;5(8):1147-8

Laboratory for Energy Metabolism, ETH Zurich, Zurich, Switzerland.

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http://dx.doi.org/10.1002/emmm.201303094DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3944455PMC
August 2013

Mitochondria and metabolic homeostasis.

Antioxid Redox Signal 2013 Jul 28;19(3):240-2. Epub 2013 Mar 28.

Department of Human Nutrition, Foods and Exercise, College of Agriculture and Life Science, Fralin Life Science Institute, Virginia Tech, Blacksburg, Virginia 24061, USA.

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http://www.liebertpub.com/doi/10.1089/ars.2013.5255
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http://dx.doi.org/10.1089/ars.2013.5255DOI Listing
July 2013

Lipid-lowering fibrates extend C. elegans lifespan in a NHR-49/PPARalpha-dependent manner.

Aging (Albany NY) 2013 Apr;5(4):270-5

Department of Human Nutrition, Institute of Nutrition, University of Jena, Jena D-07743, Germany.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3651519PMC
http://dx.doi.org/10.18632/aging.100548DOI Listing
April 2013

L-Theanine extends lifespan of adult Caenorhabditis elegans.

Eur J Nutr 2012 Sep 16;51(6):765-8. Epub 2012 Mar 16.

Department of Human Nutrition, Institute of Nutrition, University of Jena, Jena, Germany.

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http://dx.doi.org/10.1007/s00394-012-0341-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3419347PMC
September 2012

Specific alterations of carbohydrate metabolism are associated with hepatocarcinogenesis in mitochondrially impaired mice.

Hum Mol Genet 2012 Feb 3;21(3):656-63. Epub 2011 Nov 3.

Institute for Food Toxicology and Analytical Chemistry, University of Veterinary Medicine Hannover, Bischofsholer Damm 15, 30173 Hannover, Germany.

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http://dx.doi.org/10.1093/hmg/ddr499DOI Listing
February 2012

Antioxidant supplements in exercise: worse than useless?

Am J Physiol Endocrinol Metab 2012 Feb;302(4):E476-7; author reply E478-9

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http://dx.doi.org/10.1152/ajpendo.00567.2011DOI Listing
February 2012

Interview with Michael Ristow.

Authors:
Michael Ristow

Aging (Albany NY) 2012 Jan;4(1)

Buck Institute for Research on Aging, Novato, CA 94945, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3292900PMC
http://dx.doi.org/10.18632/aging.100430DOI Listing
January 2012

High activity enables life on a high-sugar diet: blood glucose regulation in nectar-feeding bats.

Proc Biol Sci 2011 Dec 13;278(1724):3490-6. Epub 2011 Apr 13.

Leibniz Institute for Zoo and Wildlife Research, Alfred-Kowalke-Strasse 17, 10315 Berlin, Germany.

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http://dx.doi.org/10.1098/rspb.2011.0465DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3189374PMC
December 2011

Low-dose lithium uptake promotes longevity in humans and metazoans.

Eur J Nutr 2011 Aug 8;50(5):387-9. Epub 2011 Feb 8.

Department of Human Nutrition, Institute of Nutrition, University of Jena, Germany.

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http://dx.doi.org/10.1007/s00394-011-0171-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3151375PMC
August 2011

Extending life span by increasing oxidative stress.

Free Radic Biol Med 2011 Jul 14;51(2):327-36. Epub 2011 May 14.

Department of Human Nutrition, Institute of Nutrition, University of Jena, D-07743 Jena, Germany.

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http://dx.doi.org/10.1016/j.freeradbiomed.2011.05.010DOI Listing
July 2011

In silico evidence for gluconeogenesis from fatty acids in humans.

PLoS Comput Biol 2011 Jul 21;7(7):e1002116. Epub 2011 Jul 21.

Department of Bioinformatics, School of Biology and Pharmaceutics, Friedrich Schiller University of Jena, Jena, Germany.

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http://dx.doi.org/10.1371/journal.pcbi.1002116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3140964PMC
July 2011

Inhibition of alanine aminotransferase in silico and in vivo promotes mitochondrial metabolism to impair malignant growth.

J Biol Chem 2011 Jun 3;286(25):22323-30. Epub 2011 May 3.

Department of Human Nutrition, Institute of Nutrition, University of Jena, Jena D-07743, Germany.

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http://dx.doi.org/10.1074/jbc.M110.205229DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3121379PMC
June 2011

Prevailing negative soil biota effect and no evidence for local adaptation in a widespread Eurasian grass.

PLoS One 2011 Mar 29;6(3):e17580. Epub 2011 Mar 29.

Institute of Biology/Geobotany and Botanical Garden, Martin Luther University Halle-Wittenberg, Halle, Germany.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0017580PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3066189PMC
March 2011

Proapoptotic effects of long-chain vitamin E metabolites in HepG2 cells are mediated by oxidative stress.

Free Radic Biol Med 2010 Nov 6;49(8):1315-22. Epub 2010 Aug 6.

Department of Human Nutrition, Institute of Nutrition, Friedrich-Schiller-University of Jena, Jena, Germany.

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http://linkinghub.elsevier.com/retrieve/pii/S089158491000464
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http://dx.doi.org/10.1016/j.freeradbiomed.2010.07.024DOI Listing
November 2010

The Friedreich's ataxia protein frataxin modulates DNA base excision repair in prokaryotes and mammals.

Biochem J 2010 Nov;432(1):165-72

Department of Food Toxicology and Replacement/Complementary Methods to Animal Testing, University of Veterinary Medicine Hannover, Germany.

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http://dx.doi.org/10.1042/BJ20101116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2976068PMC
November 2010

Opposing effects of dietary sugar and saturated fat on cardiovascular risk factors and glucose metabolism in mitochondrially impaired mice.

Eur J Nutr 2010 Oct 10;49(7):417-27. Epub 2010 Mar 10.

Department of Human Nutrition, Institute of Nutrition, University of Jena, 07743 Jena, Germany.

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http://dx.doi.org/10.1007/s00394-010-0100-4DOI Listing
October 2010

How increased oxidative stress promotes longevity and metabolic health: The concept of mitochondrial hormesis (mitohormesis).

Exp Gerontol 2010 Jun 27;45(6):410-8. Epub 2010 Mar 27.

Dept. of Human Nutrition, Institute of Nutrition, University of Jena, Germany.

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http://dx.doi.org/10.1016/j.exger.2010.03.014DOI Listing
June 2010

High glucose-induced oxidative stress increases transient receptor potential channel expression in human monocytes.

Diabetes 2010 Apr 12;59(4):844-9. Epub 2010 Jan 12.

Charité Campus Benjamin Franklin, Med. Klinik Nephrologie, Berlin, Germany.

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http://dx.doi.org/10.2337/db09-1100DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2844832PMC
April 2010

Small-molecule targeting of the mitochondrial compartment with an endogenously cleaved reversible tag.

Chembiochem 2009 Jul;10(10):1689-96

Department of Human Nutrition, Friedrich Schiller University Jena, Dornburger Strasse 29, Jena, Germany.

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http://dx.doi.org/10.1002/cbic.200900159DOI Listing
July 2009

Antioxidants prevent health-promoting effects of physical exercise in humans.

Proc Natl Acad Sci U S A 2009 May 11;106(21):8665-70. Epub 2009 May 11.

Department of Human Nutrition, Institute of Nutrition, University of Jena, Jena D-07743, Germany.

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http://www.pnas.org/cgi/doi/10.1073/pnas.0903485106
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http://dx.doi.org/10.1073/pnas.0903485106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2680430PMC
May 2009

Deficiency of glucose-dependent insulinotropic polypeptide receptor prevents ovariectomy-induced obesity in mice.

Am J Physiol Endocrinol Metab 2008 Aug 27;295(2):E350-5. Epub 2008 May 27.

Department of Endocrinology, Diabetes and Nutrition, Charité-University-Medicine, Campus Benjamin Franklin, Hindenburgdamm 30, Berlin, Germany.

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http://www.physiology.org/doi/10.1152/ajpendo.00008.2008
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http://dx.doi.org/10.1152/ajpendo.00008.2008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2519752PMC
August 2008

Improved glucose metabolism in mice lacking alpha-tocopherol transfer protein.

Eur J Nutr 2007 Oct 19;46(7):397-405. Epub 2007 Sep 19.

Dept. of Human Nutrition, Inst. of Nutrition, University of Jena, Dornburger Strasse 29, 07743, Jena, Germany.

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http://dx.doi.org/10.1007/s00394-007-0679-2DOI Listing
October 2007

Glucose restriction extends Caenorhabditis elegans life span by inducing mitochondrial respiration and increasing oxidative stress.

Cell Metab 2007 Oct;6(4):280-93

Department of Human Nutrition, Institute of Nutrition, University of Jena, D-07743 Jena, Germany.

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http://dx.doi.org/10.1016/j.cmet.2007.08.011DOI Listing
October 2007

Rat insulin promoter 2-Cre recombinase mice bred onto a pure C57BL/6J background exhibit unaltered glucose tolerance.

J Endocrinol 2007 Sep;194(3):551-5

Department of Experimental Medical Science, Lund University, SE-22184 Lund, Sweden.

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http://dx.doi.org/10.1677/JOE-07-0161DOI Listing
September 2007

Impaired respiration is positively correlated with decreased life span in Caenorhabditis elegans models of Friedreich Ataxia.

FASEB J 2007 Apr 10;21(4):1271-5. Epub 2007 Jan 10.

Department of Human Nutrition, Inst. of Nutrition, University of Jena, 29 Dornburger St., Jena D-07743, Germany.

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http://www.fasebj.org/doi/10.1096/fj.06-6994com
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http://dx.doi.org/10.1096/fj.06-6994comDOI Listing
April 2007

Reduced expression of mitochondrial frataxin in mice exacerbates diet-induced obesity.

Proc Natl Acad Sci U S A 2007 Apr 2;104(15):6377-81. Epub 2007 Apr 2.

Department of Clinical Nutrition, German Institute of Human Nutrition, D-14558 Potsdam-Rehbrücke, Germany.

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http://dx.doi.org/10.1073/pnas.0611631104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1847459PMC
April 2007

Oxidative metabolism in cancer growth.

Authors:
Michael Ristow

Curr Opin Clin Nutr Metab Care 2006 Jul;9(4):339-45

Department of Human Nutrition, Institute of Nutrition, University of Jena, Jena, Germany.

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http://dx.doi.org/10.1097/01.mco.0000232892.43921.98DOI Listing
July 2006

Acetylsalicylic acid improves lipid-induced insulin resistance in healthy men.

J Clin Endocrinol Metab 2006 Mar 29;91(3):964-7. Epub 2005 Dec 29.

German Institute of Human Nutrition Potsdam- Rehbruecke, Department of Clinical Nutrition, Arthur-Scheunert-Allee 114-116, 14558 Nuthetal, Germany.

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https://academic.oup.com/jcem/article-lookup/doi/10.1210/jc.
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http://dx.doi.org/10.1210/jc.2005-1889DOI Listing
March 2006

RIP-Cre revisited, evidence for impairments of pancreatic beta-cell function.

J Biol Chem 2006 Feb 1;281(5):2649-53. Epub 2005 Dec 1.

Laboratory of Genetics and Physiology, NIDDK, National Institutes of Health, Bethesda, Maryland 20892, USA.

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http://dx.doi.org/10.1074/jbc.M512373200DOI Listing
February 2006

Predictors of abnormal glucose metabolism in women with polycystic ovary syndrome.

Eur J Endocrinol 2006 Feb;154(2):295-301

Department of Clinical Nutrition, German Institute of Human Nutrition Potsdam-Rehbruecke, Germany.

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https://eje.bioscientifica.com/view/journals/eje/154/2/15402
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http://dx.doi.org/10.1530/eje.1.02095DOI Listing
February 2006

Induction of oxidative metabolism by mitochondrial frataxin inhibits cancer growth: Otto Warburg revisited.

J Biol Chem 2006 Jan 1;281(2):977-81. Epub 2005 Nov 1.

German Institute of Human Nutrition Potsdam-Rehbrücke, Nuthetal.

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http://dx.doi.org/10.1074/jbc.M511064200DOI Listing
January 2006

Targeted disruption of hepatic frataxin expression causes impaired mitochondrial function, decreased life span and tumor growth in mice.

Hum Mol Genet 2005 Dec 8;14(24):3857-64. Epub 2005 Nov 8.

German Institute of Human Nutrition Potsdam-Rehbrücke, Nuthetal-Berlin, and Charité University Medicine, Berlin, Germany.

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http://dx.doi.org/10.1093/hmg/ddi410DOI Listing
December 2005

Consuming fructose-sweetened beverages increases body adiposity in mice.

Obes Res 2005 Jul;13(7):1146-56

Department of Pharmacology, German Institute of Human Nutrition, Potsdam-Rehbruecke, Arthur-Scheunert-Allee 114-116, 14558 Nuthetal, Germany.

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http://dx.doi.org/10.1038/oby.2005.136DOI Listing
July 2005

Modulation of Cyp3a11 mRNA expression by alpha-tocopherol but not gamma-tocotrienol in mice.

Free Radic Biol Med 2005 Feb;38(4):507-14

Department of Biochemistry of Micronutrients, German Institute of Human Nutrition, Potsdam-Rehbrücke, Arthur-Scheunert-Allee 114-116, D-14558 Nuthetal, Germany.

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http://dx.doi.org/10.1016/j.freeradbiomed.2004.11.010DOI Listing
February 2005

Adiponectin is independently associated with insulin sensitivity in women with polycystic ovary syndrome.

Clin Endocrinol (Oxf) 2004 Dec;61(6):738-46

Department of Clinical Nutrition, German Institute of Human Nutrition, Charité-University Medicine Berlin, Campus Benjamin Franklin, Berlin, Germany.

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http://dx.doi.org/10.1111/j.1365-2265.2004.02159.xDOI Listing
December 2004

Neurodegenerative disorders associated with diabetes mellitus.

Authors:
Michael Ristow

J Mol Med (Berl) 2004 Aug 3;82(8):510-29. Epub 2004 Jun 3.

Department of Clinical Nutrition, German Institute for Human Nutrition, Potsdam-Rehbrücke, 114 Arthur-Scheunert-Allee, 14558, Nuthetal-Berlin, Germany.

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http://dx.doi.org/10.1007/s00109-004-0552-1DOI Listing
August 2004

Impaired mitochondrial activity and insulin-resistant offspring of patients with type 2 diabetes.

N Engl J Med 2004 Jun;350(23):2419-21; author reply 2419-21

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June 2004

Body mass index and C-174G interleukin-6 promoter polymorphism interact in predicting type 2 diabetes.

J Clin Endocrinol Metab 2004 Apr;89(4):1885-90

Department of Clinical Nutrition, German Institute of Human Nutrition Potsdam-Rehbruecke, 14558 Nuthetal, Germany.

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http://dx.doi.org/10.1210/jc.2003-031101DOI Listing
April 2004

The polycystic ovary syndrome per se is not associated with increased chronic inflammation.

Eur J Endocrinol 2004 Apr;150(4):525-32

Department of Clinical Nutrition, German Institute of Human Nutrition, 14558 Potsdam-Rehbruecke, Germany.

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http://dx.doi.org/10.1530/eje.0.1500525DOI Listing
April 2004

Adiponectin and protection against type 2 diabetes mellitus.

Lancet 2003 Jan;361(9353):226-8

Department of Nutrition, Endocrinology, and Metabolism, Benjamin Franklin Medical Centre, Free University Berlin, Germany.

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http://dx.doi.org/10.1016/S0140-6736(03)12255-6DOI Listing
January 2003

The yeast frataxin homolog Yfh1p plays a specific role in the maturation of cellular Fe/S proteins.

Hum Mol Genet 2002 Aug;11(17):2025-36

Institut für Zytobiologie und Zytopathologie, Philipps-Universität Marburg, Robert-Koch Str. 5, 35033 Marburg, Germany.

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http://dx.doi.org/10.1093/hmg/11.17.2025DOI Listing
August 2002

Frataxin promotes antioxidant defense in a thiol-dependent manner resulting in diminished malignant transformation in vitro.

Hum Mol Genet 2002 Apr;11(7):815-21

Center for Molecular Medicine, Clinic III for Internal Medicine and Center for Physiology and Pathophysiology, University of Cologne, Germany.

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http://dx.doi.org/10.1093/hmg/11.7.815DOI Listing
April 2002