Michael R Savona

Michael R Savona

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Michael R Savona

Michael R Savona

Publications by authors named "Michael R Savona"

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54Publications

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The evolving role of next generation sequencing in myelodysplastic syndromes.

Br J Haematol 2019 Oct 1. Epub 2019 Oct 1.

Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN, USA.

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http://dx.doi.org/10.1111/bjh.16212DOI Listing
October 2019

Symptom Burden and Blood Counts in Patients With Polycythemia Vera in the United States: An Analysis From the REVEAL Study.

Clin Lymphoma Myeloma Leuk 2019 Sep 13;19(9):579-584.e1. Epub 2019 Jun 13.

Department of Hematology and Oncology, The University of Texas Health Science Center, San Antonio, TX.

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http://dx.doi.org/10.1016/j.clml.2019.06.001DOI Listing
September 2019

A Phase Ib/II Study of Oprozomib in Patients with Advanced Multiple Myeloma and Waldenström Macroglobulinemia.

Clin Cancer Res 2019 Aug 29;25(16):4907-4916. Epub 2019 May 29.

Myeloma Research, Sarah Cannon Research Institute, Nashville, Tennessee.

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http://dx.doi.org/10.1158/1078-0432.CCR-18-3728DOI Listing
August 2019

Incorporating Precision BH3 Warheads Into the Offensive Against Acute Myeloid Leukemia.

J Clin Oncol 2019 Jul 21;37(21):1785-1789. Epub 2019 May 21.

2 Alfred Hospital, Melbourne, VIC, Australia.

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https://ascopubs.org/doi/10.1200/JCO.19.00400
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http://dx.doi.org/10.1200/JCO.19.00400DOI Listing
July 2019

Mitochondrial Homeostasis in AML and Gasping for Response in Resistance to BCL2 Blockade.

Cancer Discov 2019 Jul;9(7):831-833

Vanderbilt Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee.

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http://dx.doi.org/10.1158/2159-8290.CD-19-0510DOI Listing
July 2019

The CDK7 inhibitor THZ1 alters RNA polymerase dynamics at the 5' and 3' ends of genes.

Nucleic Acids Res 2019 May;47(8):3921-3936

Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, TN 37232, USA.

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http://dx.doi.org/10.1093/nar/gkz127DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6486546PMC
May 2019

Acceleration of spleen segmentation with end-to-end deep learning method and automated pipeline.

Comput Biol Med 2019 Apr 5;107:109-117. Epub 2019 Feb 5.

Department of Electrical Engineering, Vanderbilt University, 2301 Vanderbilt Pl, Nashville, TN, 37235, USA; Vanderbilt University Institute of Imaging Science, 161 21st Avenue South, Nashville, TN, 37232, USA. Electronic address:

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http://dx.doi.org/10.1016/j.compbiomed.2019.01.018DOI Listing
April 2019

Low clinical trial accrual of patients with myelodysplastic syndromes: Causes and potential solutions.

Cancer 2018 12 5;124(24):4601-4609. Epub 2018 Oct 5.

Department of Hematology and Medical Oncology, Cleveland Clinic Taussig Cancer Institute, Cleveland, Ohio.

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http://doi.wiley.com/10.1002/cncr.31769
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http://dx.doi.org/10.1002/cncr.31769DOI Listing
December 2018

Leveraging JAK-STAT regulation in myelofibrosis to improve outcomes with allogeneic hematopoietic stem-cell transplant.

Ther Adv Hematol 2018 Sep 16;9(9):251-259. Epub 2018 Jul 16.

Vanderbilt-Ingram Cancer, Vanderbilt University School of Medicine, Nashville, TN, USA.

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http://dx.doi.org/10.1177/2040620718786437DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6130097PMC
September 2018

Genotypic and clinical heterogeneity within NCCN favorable-risk acute myeloid leukemia.

Leuk Res 2018 02 2;65:67-73. Epub 2018 Jan 2.

Department of Pathology, Microbiology, and Immunology, Vanderbilt University School of Medicine, Nashville, TN, United States. Electronic address:

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http://dx.doi.org/10.1016/j.leukres.2017.12.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5856485PMC
February 2018

Therapy for Chronic Myelomonocytic Leukemia in a New Era.

Curr Hematol Malig Rep 2017 10;12(5):468-477

Department of Medicine, Vanderbilt University Medical Center, 2220 Pierce Avenue, 777 Preston Research Building, Nashville, TN, 37232, USA.

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http://dx.doi.org/10.1007/s11899-017-0408-8DOI Listing
October 2017

The Challenge of Treating Myelodysplastic Syndromes/Myeloproliferative Neoplasms.

Clin Lymphoma Myeloma Leuk 2017 07;17S:S37-S42

Division of Hematology and Oncology, Vanderbilt University Medical Center, Nashville, TN; Vanderbilt-Ingram Cancer Center, Nashville, TN. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S21522650173021
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http://dx.doi.org/10.1016/j.clml.2017.02.012DOI Listing
July 2017

A phase 2 study of simtuzumab in patients with primary, post-polycythaemia vera or post-essential thrombocythaemia myelofibrosis.

Br J Haematol 2017 Mar 21;176(6):939-949. Epub 2017 Feb 21.

Stanford University School of Medicine/Stanford Cancer Institute, Stanford, CA, USA.

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http://dx.doi.org/10.1111/bjh.14501DOI Listing
March 2017

Molecular Testing in Patients with Suspected Myelodysplastic Syndromes.

Curr Hematol Malig Rep 2016 12;11(6):441-448

Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.

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http://dx.doi.org/10.1007/s11899-016-0356-8DOI Listing
December 2016

High-Resolution Mapping of RNA Polymerases Identifies Mechanisms of Sensitivity and Resistance to BET Inhibitors in t(8;21) AML.

Cell Rep 2016 08 4;16(7):2003-16. Epub 2016 Aug 4.

Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, TN 37232, USA; Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN 37232, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2016.07.032DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4996374PMC
August 2016

Myelodysplastic Syndrome Revealed by Systems Immunology in a Melanoma Patient Undergoing Anti-PD-1 Therapy.

Cancer Immunol Res 2016 06 10;4(6):474-480. Epub 2016 Mar 10.

Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN.

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http://dx.doi.org/10.1158/2326-6066.CIR-15-0213DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4891280PMC
June 2016

Therapeutic approaches in myelofibrosis and myelodysplastic/myeloproliferative overlap syndromes.

Onco Targets Ther 2016 15;9:2273-86. Epub 2016 Apr 15.

Department of Internal Medicine, Vanderbilt University Medical Center, Nashville, TN, USA; Vanderbilt-Ingram Cancer Center, Nashville, TN, USA.

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http://dx.doi.org/10.2147/OTT.S83868DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4844455PMC
May 2016

Unfavorable-risk acute myeloid leukemia dissected.

Curr Opin Hematol 2016 Mar;23(2):144-9

Vanderbilt-Ingram Cancer Center, Nashville, Tennessee, USA.

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http://dx.doi.org/10.1097/MOH.0000000000000225DOI Listing
March 2016

Are we altering the natural history of primary myelofibrosis?

Authors:
Michael R Savona

Leuk Res 2014 Sep 9;38(9):1004-12. Epub 2014 May 9.

Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA. Electronic address:

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http://dx.doi.org/10.1016/j.leukres.2014.04.012DOI Listing
September 2014

Molecular monitoring and minimal residual disease in the management of chronic myelogenous leukemia.

Authors:
Michael R Savona

J Community Support Oncol 2014 May;12(5):171-8

Vanderbilt University Medical Center, Nashville, TN USA

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May 2014

Identifying the time to change BCR-ABL inhibitor therapy in patients with chronic myeloid leukemia.

Acta Haematol 2013 15;130(4):268-78. Epub 2013 Aug 15.

Sarah Cannon Research Institute, Nashville, Tenn., USA.

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https://www.karger.com/Article/FullText/353163
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http://dx.doi.org/10.1159/000353163DOI Listing
January 2014

HIV-1 utilizes the CXCR4 chemokine receptor to infect multipotent hematopoietic stem and progenitor cells.

Cell Host Microbe 2011 Mar;9(3):223-234

Graduate Program in Cellular and Molecular Biology, University of Michigan, Ann Arbor, MI 48109, USA; Medical Scientist Training Program, University of Michigan, Ann Arbor, MI 48109, USA; Department of Microbiology and Immunology, University of Michigan, Ann Arbor, MI 48109, USA; Department of Internal Medicine, University of Michigan, Ann Arbor, MI 48109, USA. Electronic address:

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http://dx.doi.org/10.1016/j.chom.2011.02.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3102232PMC
March 2011

CD9 phones home with a TEM of its own.

Blood 2011 Feb;117(6):1775-6

San Antonio Military Medical Center, USA.

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http://www.bloodjournal.org/content/117/6/1775.full.pdf
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http://www.bloodjournal.org/cgi/doi/10.1182/blood-2010-11-32
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http://dx.doi.org/10.1182/blood-2010-11-320077DOI Listing
February 2011

HIV-1 infects multipotent progenitor cells causing cell death and establishing latent cellular reservoirs.

Nat Med 2010 Apr 7;16(4):446-51. Epub 2010 Mar 7.

Graduate Program in Cellular and Molecular Biology, University of Michigan, Ann Arbor, Michigan, USA.

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http://www.nature.com/articles/nm.2109
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http://dx.doi.org/10.1038/nm.2109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2892382PMC
April 2010

Overcoming resistance in chronic myelogenous leukemia.

Leuk Lymphoma 2009 Nov;50(11):1785-93

Division of Hematology-Oncology, Department of Medicine, San Antonio Military Medical Center, San Antonio, TX 78236, USA.

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http://dx.doi.org/10.3109/10428190903267559DOI Listing
November 2009

The use of higher dose clofarabine in adults with relapsed acute lymphoblastic leukemia.

Am J Hematol 2009 Apr;84(4):228-30

Department of Medicine, Hematology-Oncology, San Antonio Military Medical Center, San Antonio, Texas, USA.

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http://dx.doi.org/10.1002/ajh.21365DOI Listing
April 2009

Erythropoietin-stimulating agents in oncology.

Cancer J 2008 Mar-Apr;14(2):75-84

University of Michigan, Ann Arbor, MI 48109-5843, USA.

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https://insights.ovid.com/crossref?an=00130404-200803000-000
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http://dx.doi.org/10.1097/PPO.0b013e31816a5f51DOI Listing
September 2008

Comparison of a semipermeable dressing bonded to an absorbent pad and a semipermeable dressing over a separate gauze pad for containment of vaccinia virus at the vaccination site.

Infect Control Hosp Epidemiol 2007 Dec 19;28(12):1339-43. Epub 2007 Oct 19.

Division of Hematology and Oncology, Department of Internal Medicine, University of Michigan, Ann Arbor, USA.

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https://www.cambridge.org/core/product/identifier/S019594170
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http://dx.doi.org/10.1086/523277DOI Listing
December 2007