Michael R Dashwood

Michael R Dashwood

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Michael R Dashwood

Michael R Dashwood

Publications by authors named "Michael R Dashwood"

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Regional Distribution of Nitric Oxide Synthase in Human Anorectal Tissue: A Pilot Study on the Potential Role for Nitric Oxide in Haemorrhoids.

Curr Vasc Pharmacol 2020 ;18(1):43-49

Surgical and Interventional Sciences, Royal Free and University College Medical School, London, United Kingdom.

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http://dx.doi.org/10.2174/1570161116666180730101532DOI Listing
January 2020

Why 'EXTENT' for coronary artery bypass surgery when the saphenous vein should need no support?

Eur J Cardiothorac Surg 2019 May;55(5):1021

Division of Surgery and Interventional Science, University College London Medical School, London, UK.

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http://dx.doi.org/10.1093/ejcts/ezy412DOI Listing
May 2019

Arterial versus venous conduits in coronary artery bypass surgery: Comparing apples with oranges.

J Thorac Cardiovasc Surg 2019 05 10;157(5):e253-e254. Epub 2019 Feb 10.

Centre for Rheumatology, Royal Free Hospital Campus, University College Medical School, London, United Kingdom.

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http://dx.doi.org/10.1016/j.jtcvs.2018.11.047DOI Listing
May 2019

Endoscopic versus Open Vein-Graft Harvesting for CABG.

N Engl J Med 2019 05;380(22):e43

University College London, London, United Kingdom

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http://dx.doi.org/10.1056/NEJMc1904533DOI Listing
May 2019

Vasa vasorum inside out/outside in communication: a potential role in the patency of saphenous vein coronary artery bypass grafts.

J Cell Commun Signal 2018 Dec 4;12(4):631-643. Epub 2018 Aug 4.

Division of Surgery and Interventional Science, Faculty of Medical Sciences, University College London Medical School, Royal Free Campus, Rowland Hill Street, London, NW3 2PF, UK.

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http://link.springer.com/10.1007/s12079-018-0483-1
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http://dx.doi.org/10.1007/s12079-018-0483-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6235771PMC
December 2018

Pedicled Vein Grafts in Coronary Operation: No-Touch Harvesting Under Pressure.

Ann Thorac Surg 2018 06;105(6):1863

Surgical and Interventional Sciences, Royal Free Hospital Campus, University College Medical School, Pond St, London NW3 2QG, United Kingdom. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00034975173134
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http://dx.doi.org/10.1016/j.athoracsur.2017.09.056DOI Listing
June 2018

Nerve-perivascular fat communication as a potential influence on the performance of blood vessels used as coronary artery bypass grafts.

J Cell Commun Signal 2018 Mar 10;12(1):181-191. Epub 2017 Jun 10.

Division of Surgery and Interventional Science, Faculty of Medical Sciences, University College London Medical School, Royal Free Campus, Rowland Hill Street, NW3 2PF, London, UK.

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http://dx.doi.org/10.1007/s12079-017-0393-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5842173PMC
March 2018

Commentary: Perivascular Fat and Improved Vein Graft Patency in Patients Undergoing Coronary Artery Bypass Surgery.

Curr Vasc Pharmacol 2016 ;14(4):308-12

Royal Free Hospital Campus, University College Medical School, Surgical and Interventional Sciences, Pond Street, London NW3 2QG, United Kingdom.

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http://dx.doi.org/10.2174/1570161114666160513150444DOI Listing
January 2018

Saphenous vein graft harvesting and patency: No-touch harvesting is the answer.

J Thorac Cardiovasc Surg 2017 10;154(4):1300-1301

Department of Cardiothoracic and Vascular Surgery, Faculty of Medicine and Health, Örebro University, Örebro, Sweden.

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http://dx.doi.org/10.1016/j.jtcvs.2017.02.010DOI Listing
October 2017

Endothelin-1 and its receptors on haemorrhoidal tissue: a potential site for therapeutic intervention.

Br J Pharmacol 2017 04 16;174(7):569-579. Epub 2017 Feb 16.

Royal Free Hospital Campus, University College Medical School, London, UK.

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http://dx.doi.org/10.1111/bph.13719DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5345667PMC
April 2017

Neointima development in externally stented saphenous vein grafts. External stents are bad for the patient: why not use an undamaged saphenous vein for coronary artery bypass graft?

Postepy Kardiol Interwencyjnej 2017 10;13(1):90-91. Epub 2017 Mar 10.

Centre for Rheumatology and Connective Tissue Diseases, Royal Free Hospital Campus, University College London Medical School, London, United Kingdom.

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http://dx.doi.org/10.5114/aic.2017.66197DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5364293PMC
March 2017

Adiponectin: An Endothelium-Derived Vasoprotective Factor?

Curr Vasc Pharmacol 2016 ;14(2):168-74

Life Sciences Research Division, ADLQ, P.O Box 27775, Doha, Qatar.

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http://dx.doi.org/10.2174/1570161114666151202210128DOI Listing
December 2016

Editorial: Endothelium: A Target for Therapeutic Intervention.

Curr Vasc Pharmacol 2016 ;14(2):126-9

Surgical and Interventional Sciences, Royal Free Hospital Campus, University College Medical School, Pond Street, London, NW3 2PF, UK.

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http://dx.doi.org/10.2174/157016111402160208120152DOI Listing
December 2016

Three arteries versus the saphenous vein for coronary artery bypass graft: Why use a damaged graft to repair a damaged heart?

J Thorac Cardiovasc Surg 2016 11;152(5):1460-1462

Surgical and Interventional Sciences, Royal Free Hospital Campus, University College Medical School, London, United Kingdom.

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http://dx.doi.org/10.1016/j.jtcvs.2016.06.028DOI Listing
November 2016

Endoscopic Versus "No-Touch" Saphenous Vein Harvesting for Coronary Artery Bypass Grafting: A Trade-Off Between Wound Healing and Graft Patency.

Angiology 2016 Feb 13;67(2):121-32. Epub 2015 May 13.

Surgical and Interventional Sciences, Royal Free Hospital Campus, University College Medical School, London, United Kingdom

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http://dx.doi.org/10.1177/0003319715584126DOI Listing
February 2016

IS local wound infection rate more important than long-term graft patency in coronary artery bypass grafting?

J Thorac Cardiovasc Surg 2016 Jan;151(1):275

University of Zagreb School of Medicine, Department of Cardiac Surgery, University Hospital Center Zagreb, Zagreb, Croatia.

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http://dx.doi.org/10.1016/j.jtcvs.2015.09.066DOI Listing
January 2016

Immunoreactive endothelin-1 and endothelin a receptor in basilar artery perivascular nerves of young and adult capybaras.

Cells Tissues Organs 2013 4;198(1):47-56. Epub 2013 May 4.

Division of Medicine, University College London Medical School, London NW3 2PF, UK.

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http://dx.doi.org/10.1159/000348617DOI Listing
February 2014

Inducible nitric oxide synthase and vein graft performance in patients undergoing coronary artery bypass surgery: physiological or pathophysiological role?

Curr Vasc Pharmacol 2014 Jan;12(1):144-51

Department of Clinical Biochemistry, Royal Free and University College Medical School, Pond Street, London NW3 2QG, UK.

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http://dx.doi.org/10.2174/157016111201140327164409DOI Listing
January 2014

Efficacy of the specific endothelin a receptor antagonist zibotentan (ZD4054) in colorectal cancer: a preclinical study.

Mol Cancer Ther 2013 Aug 30;12(8):1556-67. Epub 2013 May 30.

Cancer Nanotechnology Group, UCL Division of Surgery and Interventional Science, Royal Free Hospital, UK.

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http://dx.doi.org/10.1158/1535-7163.MCT-12-0975DOI Listing
August 2013

The vasa vasorum and associated endothelial nitric oxide synthase is more important for saphenous vein than arterial bypass grafts.

Angiology 2013 May 7;64(4):293-9. Epub 2012 May 7.

Department of Thoracic and Cardiovascular Surgery, Örebro University Hospital, Sweden.

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http://dx.doi.org/10.1177/0003319712443729DOI Listing
May 2013

'No-touch' saphenous vein harvesting improves graft performance in patients undergoing coronary artery bypass surgery: a journey from bedside to bench.

Vascul Pharmacol 2013 Mar 8;58(3):240-50. Epub 2012 Aug 8.

Department of Clinical Biochemistry, Royal Free and University College Medical School, Pond Street, London NW3 2QG, United Kingdom.

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http://dx.doi.org/10.1016/j.vph.2012.07.008DOI Listing
March 2013

Distension of the saphenous vein during graft preparation: markers of inflammation or endothelium?

Ann Thorac Surg 2012 Dec;94(6):2177-8; author reply 2178-9

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http://dx.doi.org/10.1016/j.athoracsur.2012.04.132DOI Listing
December 2012

Determination of cell-specific receptor binding using a combination of immunohistochemistry and in vitro autoradiography: relevance to therapeutic receptor targeting in cancer.

Methods Mol Biol 2012 ;878:137-47

Department of Clinical Biochemistry, Royal Free and UCL Medical School, London, UK.

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http://dx.doi.org/10.1007/978-1-61779-854-2_9DOI Listing
October 2012

Endothelin-1 stimulates colon cancer adjacent fibroblasts.

Int J Cancer 2012 Mar 9;130(6):1264-72. Epub 2011 Jun 9.

Department of Surgery, UCL Division of Surgery and Interventional Science, London, United Kingdom.

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http://dx.doi.org/10.1002/ijc.26090DOI Listing
March 2012

Identification of neuronal nitric oxide synthase (nNOS) in human penis: a potential role of reduced neuronally-derived nitric oxide in erectile dysfunction.

Curr Pharm Biotechnol 2011 Sep;12(9):1316-21

Clinical Biochemistry, Royal Free and University College Medical School, Royal Free Campus, Pond Street, London NW3 2QG, United Kingdom.

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http://dx.doi.org/10.2174/138920111798280965DOI Listing
September 2011

Pharmacological characteristics of endothelin receptors on sheep rectal blood vessels.

Pharmacol Res 2011 Jun 5;63(6):490-5. Epub 2011 Mar 5.

Division of Gastrointestinal Surgery, Queen's Medical Centre, University of Nottingham, UK.

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http://dx.doi.org/10.1016/j.phrs.2011.02.010DOI Listing
June 2011

Endothelin: from bench to bedside and back.

Pharmacol Res 2011 Jun;63(6):445-7

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http://dx.doi.org/10.1016/j.phrs.2011.04.005DOI Listing
June 2011

Perivascular fat-derived leptin: a potential role in improved vein graft performance in coronary artery bypass surgery.

Interact Cardiovasc Thorac Surg 2011 Feb 3;12(2):170-3. Epub 2010 Nov 3.

Department of Clinical Biochemistry, Royal Free and University College Medical School, Pond Street, London NW3 2QG, UK.

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http://dx.doi.org/10.1510/icvts.2010.247874DOI Listing
February 2011

The "no-touch" harvesting technique for vein grafts in coronary artery bypass surgery preserves an intact vasa vasorum.

J Thorac Cardiovasc Surg 2011 Jan 9;141(1):145-50. Epub 2010 Apr 9.

Department of Thoracic and Cardiovascular Surgery, Örebro University Hospital, Örebro, Sweden.

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http://dx.doi.org/10.1016/j.jtcvs.2010.02.005DOI Listing
January 2011

Saphenous vein harvest with the Mayo extraluminal dissector: is endothelial function preserved?

J Thorac Cardiovasc Surg 2010 Jan;139(1):239-41; author reply 241

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http://dx.doi.org/10.1016/j.jtcvs.2009.08.054DOI Listing
January 2010

Retaining perivascular tissue of human saphenous vein grafts protects against surgical and distension-induced damage and preserves endothelial nitric oxide synthase and nitric oxide synthase activity.

J Thorac Cardiovasc Surg 2009 Aug 10;138(2):334-40. Epub 2009 Mar 10.

Department of Clinical Biochemistry, Royal Free and University College Medical School, Royal Free Campus, Pond Street, London, United Kingdom.

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http://dx.doi.org/10.1016/j.jtcvs.2008.11.060DOI Listing
August 2009

The saphenous vein as a bypass conduit: the potential role of vascular nerves in graft performance.

Curr Vasc Pharmacol 2009 Jan;7(1):47-57

Department of Clinical Biochemistry, Royal Free and University College Medical School, London NW3 2QG, UK.

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http://dx.doi.org/10.2174/157016109787354132DOI Listing
January 2009

On the sympathetic innervation of the human greater saphenous vein: relevance to clinical practice.

Curr Vasc Pharmacol 2009 Jan;7(1):58-67

Department of Medicine, Royal Free and University College Medical School, London NW3 2PF, UK.

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http://dx.doi.org/10.2174/157016109787354150DOI Listing
January 2009

Alterations in nitric oxide synthase isoforms in acute lower limb ischemia and reperfusion.

Angiology 2007 Oct-Nov;58(5):586-92

Department of Surgery, Royal Free Hospital, London, UK.

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http://dx.doi.org/10.1177/0003319707305466DOI Listing
December 2007

Endogenous endothelin-1 signaling contributes to type I collagen and CCN2 overexpression in fibrotic fibroblasts.

Matrix Biol 2007 Oct 18;26(8):625-32. Epub 2007 Jun 18.

Centre for Rheumatology, Department of Medicine, Royal Free and University College Medical School, Rowland Hill Street, London NW3 2PF, UK.

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http://dx.doi.org/10.1016/j.matbio.2007.06.003DOI Listing
October 2007

Altered endothelin receptor subtypes in colorectal cancer.

Eur J Gastroenterol Hepatol 2007 Sep;19(9):775-82

Department of Surgery, Royal Free and University College Medical School, London, UK.

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http://dx.doi.org/10.1097/MEG.0b013e3282c563deDOI Listing
September 2007

Does the method of harvesting the saphenous vein for coronary artery bypass surgery affect venous smooth muscle cells? iNOS immunolabelling and ultrastructural findings.

Int J Surg 2006 3;4(1):20-9. Epub 2006 Jan 3.

Department of Anatomy and Developmental Biology, Royal Free and University College Medical School, Hampstead Campus, Rowland Hill Street, Hampstead, London NW3 2PF, UK.

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http://dx.doi.org/10.1016/j.ijsu.2005.11.002DOI Listing
July 2007

Does periadventitial fat-derived nitric oxide play a role in improved saphenous vein graft patency in patients undergoing coronary artery bypass surgery?

J Vasc Res 2007 16;44(3):175-81. Epub 2007 Feb 16.

Department of Clinical Biochemistry, Royal Free and University College Medical School, London, UK.

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http://dx.doi.org/10.1159/000099833DOI Listing
May 2007

Surgical damage of the saphenous vein and graft patency.

J Thorac Cardiovasc Surg 2007 Jan;133(1):274-5

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http://dx.doi.org/10.1016/j.jtcvs.2006.09.029DOI Listing
January 2007

The effect of acute ischemia on ET-1 and its receptors in patients with underlying chronic ischemia of the lower limb.

Exp Biol Med (Maywood) 2006 Jun;231(6):802-5

Clinical Biochemistry, Royal Free and University College Medical School, Royal Free Campus, Pond Street, London NW3 2QG, UK.

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June 2006

A role for endothelin-1 in peripheral vascular disease.

Curr Vasc Pharmacol 2005 Oct;3(4):325-32

Southend Hospital, Prittlewell Chase, Southend-on-Sea, Essex SS0 0RY, UK.

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http://dx.doi.org/10.2174/157016105774329444DOI Listing
October 2005

Effect of vein graft harvesting on endothelial nitric oxide synthase and nitric oxide production.

Ann Thorac Surg 2005 Sep;80(3):939-44

Department of Clinical Biochemistry, Royal Free and University College Medical School, Pond Street, London, United Kingdom.

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http://dx.doi.org/10.1016/j.athoracsur.2005.03.042DOI Listing
September 2005

Endothelin-1 and endothelin receptors in the basilar artery of the capybara.

J Mol Histol 2005 Feb;36(1-2):25-34

Department of Anatomy and Developmental Biology (Royal Free Campus), Royal Free and University College Medical School, University College London, Rowland Hill Street, London, UK, NW3 2PF,

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http://dx.doi.org/10.1007/s10735-004-2912-0DOI Listing
February 2005

Hypothesis: a potential role for the vasa vasorum in the maintenance of vein graft patency.

Angiology 2004 Jul-Aug;55(4):385-95

Department of Clinical Biochemistry, Royal Free and University College Medical School, London, United Kingdom.

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http://dx.doi.org/10.1177/000331970405500405DOI Listing
September 2004

Endothelin-1 induces expression of matrix-associated genes in lung fibroblasts through MEK/ERK.

J Biol Chem 2004 May 23;279(22):23098-103. Epub 2004 Mar 23.

Centre for Rheumatology, Department of Medicine, Royal Free and University College London, United Kingdom.

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http://dx.doi.org/10.1074/jbc.M311430200DOI Listing
May 2004

Expression and cellular localisation of renal endothelin-1 and endothelin receptor subtypes in autosomal-dominant polycystic kidney disease.

Nephron Exp Nephrol 2003 ;93(2):e80

Sheffield Kidney Institute, Section of Human Metabolism, Division of Clinical Sciences (NGH), University of Sheffield, London, UK.

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http://dx.doi.org/10.1159/000068518DOI Listing
April 2003

Effect of ischemic preconditioning on hepatic microcirculation and function in a rat model of ischemia reperfusion injury.

Liver Transpl 2002 Dec;8(12):1182-91

Hepatic Haemodynamic Unit, University Department of Surgery, Royal Free and University College Medical School, University College London Royal Free Hospital, London, United Kingdom.

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http://dx.doi.org/10.1053/jlts.2002.36846DOI Listing
December 2002

Divalent metal inhibition of non-haem iron uptake across the rat duodenal brush border membrane.

Br J Nutr 2002 Jul;88(1):51-6

Epithelial Transport Laboratories, Department of Physiology, Royal Free and University College Medical School, London, UK.

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http://dx.doi.org/10.1079/BJNBJN2002587DOI Listing
July 2002

Improved patency in vein grafts harvested with surrounding tissue: results of a randomized study using three harvesting techniques.

Ann Thorac Surg 2002 Apr;73(4):1189-95

Department of Thoracic and Cardiovascular Surgery, Orebro University Hospital, Sweden.

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http://dx.doi.org/10.1016/s0003-4975(02)03425-2DOI Listing
April 2002

Endothelin-1 and atherosclerosis: potential complications associated with endothelin-receptor blockade.

Atherosclerosis 2002 Feb;160(2):297-304

Department of Molecular Pathology and Clinical Biochemistry, Royal Free and University College Medical School, Royal Free Campus, Pond Street, London NW3 2QG, UK.

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http://dx.doi.org/10.1016/s0021-9150(01)00586-xDOI Listing
February 2002

Localization of nitric oxide synthase in saphenous vein grafts harvested with a novel "no-touch" technique: potential role of nitric oxide contribution to improved early graft patency rates.

J Vasc Surg 2002 Feb;35(2):356-62

Department of Surgery, Royal Free and University College Medical School, Royal Free Campus, London, United Kingdom.

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http://dx.doi.org/10.1067/mva.2002.121072DOI Listing
February 2002

Endothelin receptors in cultured and native human radial artery smooth muscle.

J Cardiovasc Pharmacol 2002 Jan;39(1):130-41

Cardiothoracic Center, Liverpool NHS Trust, Liverpool, UK.

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http://dx.doi.org/10.1097/00005344-200201000-00014DOI Listing
January 2002