Michael R Betts

Michael R Betts

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Michael R Betts

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Everything in its right place: resident memory CD8+ T cell immunosurveillance of HIV infection.

Curr Opin HIV AIDS 2019 Mar;14(2):93-99

Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.

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http://dx.doi.org/10.1097/COH.0000000000000523DOI Listing
March 2019

Human Immunodeficiency Virus Type-1 Elite Controllers Maintain Low Co-Expression of Inhibitory Receptors on CD4+ T Cells.

Front Immunol 2018 22;9:19. Epub 2018 Jan 22.

Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States.

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http://dx.doi.org/10.3389/fimmu.2018.00019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5786543PMC
February 2019

Assessment of the Synaptic Interface of Primary Human T Cells from Peripheral Blood and Lymphoid Tissue.

J Vis Exp 2018 07 30(137). Epub 2018 Jul 30.

Departments of Microbiology and Immunology and Medical Oncology, Sidney Kimmel Cancer Center, Thomas Jefferson University;

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https://www.jove.com/video/58143/assessment-synaptic-interfa
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http://dx.doi.org/10.3791/58143DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6126586PMC
July 2018

Spatial distribution and function of T follicular regulatory cells in human lymph nodes.

J Exp Med 2018 Jun 16;215(6):1531-1542. Epub 2018 May 16.

Division of Infectious Diseases and HIV Medicine, Case Western Reserve University, Cleveland, OH

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http://dx.doi.org/10.1084/jem.20171940DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5987920PMC
June 2018

T-bet-expressing B cells during HIV and HCV infections.

Cell Immunol 2017 Nov 11;321:26-34. Epub 2017 Jul 11.

Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cellimm.2017.04.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5732046PMC
November 2017

Class I-restricted T-cell responses to a polymorphic peptide in a gene therapy clinical trial for α-1-antitrypsin deficiency.

Proc Natl Acad Sci U S A 2017 02 30;114(7):1655-1659. Epub 2017 Jan 30.

Gene Therapy Program, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104;

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http://dx.doi.org/10.1073/pnas.1617726114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5320988PMC
February 2017

Collapse of Cytolytic Potential in SIV-Specific CD8+ T Cells Following Acute SIV Infection in Rhesus Macaques.

PLoS Pathog 2016 Dec 30;12(12):e1006135. Epub 2016 Dec 30.

Department of Microbiology, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America.

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http://dx.doi.org/10.1371/journal.ppat.1006135DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5231392PMC
December 2016

Statin modulation of monocyte phenotype and function: implications for HIV-1-associated neurocognitive disorders.

J Neurovirol 2016 10 28;22(5):584-596. Epub 2016 Mar 28.

Department of Medicine, University of Pennsylvania Perelman School of Medicine, 36th and Hamilton Walk, Philadelphia, PA, 19104, USA.

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http://dx.doi.org/10.1007/s13365-016-0433-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5040617PMC
October 2016

CD4+ T cells with an activated and exhausted phenotype distinguish immunodeficiency during aviremic HIV-2 infection.

AIDS 2016 10;30(16):2415-2426

aDivision of Clinical Microbiology, Department of Laboratory Medicine, Karolinska Institutet, Stockholm, Sweden bDepartment of Microbiology, University of Pennsylvania, Philadelphia, PA, USA cCenter for Biological Sequence Analysis, Department of Systems Biology, Technical University of Denmark, Lyngby, Denmark dNational Public Health Laboratory, Bissau, Guinea-Bissau eInstituto de Investigaciones Biotecnológicas, Universidad Nacional de San Martín, Argentina fDepartment of Clinical Sciences Lund gDepartment of Translational Medicine hDepartment of Laboratory Medicine, Lund University, Lund iDepartment of Microbiology, Tumor and Cell biology, Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.1097/QAD.0000000000001223DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5051526PMC
October 2016

Corrigendum: Characterization of T-bet and Eomes in Peripheral Human Immune Cells.

Front Immunol 2016 8;7:337. Epub 2016 Sep 8.

Department of Microbiology, Perelman Institute for Immunology, University of Pennsylvania , Philadelphia, PA , USA.

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http://dx.doi.org/10.3389/fimmu.2016.00337DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5015462PMC
September 2016

Elevated Expression of CD160 and 2B4 Defines a Cytolytic HIV-Specific CD8+ T-Cell Population in Elite Controllers.

J Infect Dis 2015 Nov 15;212(9):1376-86. Epub 2015 Apr 15.

Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia.

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http://dx.doi.org/10.1093/infdis/jiv226DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4601914PMC
November 2015

CD4+ T cell polyfunctional profile in HIV-TB coinfection are similar between individuals with latent and active TB infection.

Tuberculosis (Edinb) 2015 Jul 7;95(4):470-5. Epub 2015 Jan 7.

Division of Infectious Diseases and HIV Medicine, University Hospitals of Cleveland and Case Western Reserve University School of Medicine, 10900 Euclid Ave, BRB 1022, Cleveland, OH, 44106-4984, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S14729792142058
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http://dx.doi.org/10.1016/j.tube.2014.12.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4475423PMC
July 2015

Age-related differences in polyfunctional T cell responses.

Immun Ageing 2014 23;11:14. Epub 2014 Oct 23.

Geriatric Research Center Clinical Core (GRECC), Louis Stokes Cleveland VA Medical Center, 10701 East Blvd, Cleveland, Ohio 44106, USA ; Division of Infectious Diseases, Case Western Reserve University School of Medicine, 10900 Euclid Ave, BRB 1022, Cleveland, Ohio, 44106-4684, USA.

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http://dx.doi.org/10.1186/1742-4933-11-14DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4265991PMC
December 2014

Use of transgenic parasites and host reporters to dissect events that promote interleukin-12 production during toxoplasmosis.

Infect Immun 2014 Oct 14;82(10):4056-67. Epub 2014 Jul 14.

Department of Pathobiology, University of Pennsylvania, Philadelphia, Pennsylvania, USA

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http://dx.doi.org/10.1128/IAI.01643-14DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4187868PMC
October 2014

Circulating CXCR5+PD-1+ response predicts influenza vaccine antibody responses in young adults but not elderly adults.

J Immunol 2014 Oct 29;193(7):3528-37. Epub 2014 Aug 29.

Institute for Immunology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104; Department of Microbiology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104;

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http://dx.doi.org/10.4049/jimmunol.1302503DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4170011PMC
October 2014

Increased mucosal CD4+ T cell activation in rhesus macaques following vaccination with an adenoviral vector.

J Virol 2014 Aug 14;88(15):8468-78. Epub 2014 May 14.

Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA

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http://dx.doi.org/10.1128/JVI.03850-13DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4135938PMC
August 2014

Characterization of T-bet and eomes in peripheral human immune cells.

Front Immunol 2014 14;5:217. Epub 2014 May 14.

Department of Microbiology, Perelman Institute for Immunology, University of Pennsylvania , Philadelphia, PA , USA.

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http://journal.frontiersin.org/article/10.3389/fimmu.2014.00
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http://dx.doi.org/10.3389/fimmu.2014.00217DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4030168PMC
May 2014

Commentary on Shapiro: clinical development of candidate HIV vaccines: different problems for different vaccines.

AIDS Res Hum Retroviruses 2014 Apr;30(4):330

1 Northwestern University , Feinberg School of Medicine, Chicago, Illinois.

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http://dx.doi.org/10.1089/AID.2014.0047DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3976568PMC
April 2014

Cytotoxic T cells mediate pathology and metastasis in cutaneous leishmaniasis.

PLoS Pathog 2013 18;9(7):e1003504. Epub 2013 Jul 18.

Department of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America.

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http://dx.doi.org/10.1371/journal.ppat.1003504DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3715507PMC
February 2014

Lack of recall response to Tax in ATL and HAM/TSP patients but not in asymptomatic carriers of human T-cell leukemia virus type 1.

J Clin Immunol 2013 Oct 26;33(7):1223-39. Epub 2013 Jul 26.

Department of Microbiology and Immunology, Drexel University College of Medicine, Philadelphia, PA, 19104, USA.

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http://dx.doi.org/10.1007/s10875-013-9918-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3784618PMC
October 2013

An altered maturation and adhesion phenotype of dendritic cells in diseased individuals compared to asymptomatic carriers of human T cell leukemia virus type 1.

AIDS Res Hum Retroviruses 2013 Sep 19;29(9):1273-85. Epub 2013 Jul 19.

Department of Microbiology and Immunology, Drexel University College of Medicine, Philadelphia, Pennsylvania, USA.

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http://dx.doi.org/10.1089/aid.2013.0054DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3749709PMC
September 2013

CD40L expression permits CD8+ T cells to execute immunologic helper functions.

Blood 2013 Jul 29;122(3):405-12. Epub 2013 May 29.

Regenerative Immunology and Aging, Berlin-Brandenburg Center for Regenerative Therapies, Charité University Medicine, Berlin, Germany.

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http://dx.doi.org/10.1182/blood-2013-02-483586DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4548794PMC
July 2013

CD8(+) T-cell effector function and transcriptional regulation during HIV pathogenesis.

Immunol Rev 2013 Jul;254(1):190-206

Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1111/imr.12069DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3693771PMC
July 2013

The polyfunctionality of human memory CD8+ T cells elicited by acute and chronic virus infections is not influenced by age.

PLoS Pathog 2012 13;8(12):e1003076. Epub 2012 Dec 13.

McMaster Immunology Research Centre, Department of Pathology and Molecular Medicine, McMaster University, Hamilton, Ontario, Canada.

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http://dx.plos.org/10.1371/journal.ppat.1003076
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http://dx.doi.org/10.1371/journal.ppat.1003076DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3521721PMC
May 2013

Differential localization of T-bet and Eomes in CD8 T cell memory populations.

J Immunol 2013 Apr 1;190(7):3207-15. Epub 2013 Mar 1.

Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.

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http://www.jimmunol.org/cgi/doi/10.4049/jimmunol.1201556
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http://dx.doi.org/10.4049/jimmunol.1201556DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3608800PMC
April 2013

Cytokine production and dysregulation in HIV pathogenesis: lessons for development of therapeutics and vaccines.

Cytokine Growth Factor Rev 2012 Aug-Oct;23(4-5):181-91. Epub 2012 Jun 27.

Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1016/j.cytogfr.2012.05.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3582023PMC
January 2013

DNA-based HIV vaccines do not induce generalized activation in mucosal tissue T cells.

Hum Vaccin Immunother 2012 Nov 30;8(11):1648-53. Epub 2012 Oct 30.

Department of Microbiology; Perelman School of Medicine; University of Pennsylvania; Philadelphia, PA USA.

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http://dx.doi.org/10.4161/hv.22247DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3601139PMC
November 2012

Brilliant violet fluorophores: a new class of ultrabright fluorescent compounds for immunofluorescence experiments.

Cytometry A 2012 Jun 6;81(6):456-66. Epub 2012 Apr 6.

ImmunoTechnology Section, Vaccine Research Center, NIAID, NIH, Bethesda, Maryland 20892, USA.

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http://dx.doi.org/10.1002/cyto.a.22043DOI Listing
June 2012

CD27 deficiency is associated with combined immunodeficiency and persistent symptomatic EBV viremia.

J Allergy Clin Immunol 2012 Mar 24;129(3):787-793.e6. Epub 2011 Dec 24.

Departments of Pediatric Immunology and Infectious Diseases, Wilhelmina Children's Hospital/University Medical Center Utrecht, Utrecht, The Netherlands.

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http://dx.doi.org/10.1016/j.jaci.2011.11.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3294016PMC
March 2012

Distinct kinetics of Gag-specific CD4+ and CD8+ T cell responses during acute HIV-1 infection.

J Immunol 2012 Mar 27;188(5):2198-206. Epub 2012 Jan 27.

Division of Immunology, Institute of Infectious Diseases and Molecular Medicine, University of Cape Town, Cape Town 7529, South Africa.

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http://dx.doi.org/10.4049/jimmunol.1102813DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3288487PMC
March 2012

Adenovirus-specific human T cells are pervasive, polyfunctional, and cross-reactive.

Vaccine 2010 Feb;28(8):1932-41

Microbiology Department, University of Pennsylvania, Philadelphia, PA 19104, United States.

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http://dx.doi.org/10.1016/j.vaccine.2009.10.091DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2832841PMC
February 2010

Autocrine production of beta-chemokines protects CMV-Specific CD4 T cells from HIV infection.

PLoS Pathog 2009 Oct 30;5(10):e1000646. Epub 2009 Oct 30.

Immunology Laboratory, Vaccine Research Center, NIAID, NIH, Bethesda, Maryland, USA.

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http://dx.doi.org/10.1371/journal.ppat.1000646DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2763204PMC
October 2009

AAV-1-mediated gene transfer to skeletal muscle in humans results in dose-dependent activation of capsid-specific T cells.

Blood 2009 Sep 8;114(10):2077-86. Epub 2009 Jun 8.

Division of Hematology and Center for Cellular and Molecular Therapeutics, The Children's Hospital of Philadelphia, 3615 Civic Center Blvd., Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1182/blood-2008-07-167510DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2744569PMC
September 2009

Baseline Ad5 serostatus does not predict Ad5 HIV vaccine-induced expansion of adenovirus-specific CD4+ T cells.

Nat Med 2009 Aug 20;15(8):876-8. Epub 2009 Jul 20.

Department of Microbiology and Center for AIDS Research, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA.

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http://dx.doi.org/10.1038/nm.1989DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2723179PMC
August 2009

The cytolytic enzymes granyzme A, granzyme B, and perforin: expression patterns, cell distribution, and their relationship to cell maturity and bright CD57 expression.

J Leukoc Biol 2009 Jan 10;85(1):88-97. Epub 2008 Oct 10.

ImmunoTechnology Section, Laboratory of Immunology, Vaccine Research Center, National Institutes of Health, Bethesda, MD, USA.

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http://dx.doi.org/10.1189/jlb.0208107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2638730PMC
January 2009

Coregulation of CD8+ T cell exhaustion by multiple inhibitory receptors during chronic viral infection.

Nat Immunol 2009 Jan 30;10(1):29-37. Epub 2008 Nov 30.

Immunology Program and Wistar Vaccine Center, Wistar Institute, Philadelphia, Pennsylvania 19104, USA.

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http://dx.doi.org/10.1038/ni.1679DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2605166PMC
January 2009

Flow cytometric detection of perforin upregulation in human CD8 T cells.

Cytometry A 2008 Nov;73(11):1050-7

Department of Microbiology, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.

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http://doi.wiley.com/10.1002/cyto.a.20596
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http://dx.doi.org/10.1002/cyto.a.20596DOI Listing
November 2008

Combined effects of IL-12 and electroporation enhances the potency of DNA vaccination in macaques.

Vaccine 2008 Jun 11;26(25):3112-20. Epub 2008 Mar 11.

Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, 422 Curie Boulevard, 505 SCL, Philadelphia, PA 19104, United States.

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http://dx.doi.org/10.1016/j.vaccine.2008.02.036DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4477809PMC
June 2008

Phenotype and function of protective T cell immune responses in HIV.

Curr Opin HIV AIDS 2008 May;3(3):349-55

Department of Microbiology, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.

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https://insights.ovid.com/crossref?an=01222929-200805000-000
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http://dx.doi.org/10.1097/COH.0b013e3282fbaa81DOI Listing
May 2008

Acquisition of direct antiviral effector functions by CMV-specific CD4+ T lymphocytes with cellular maturation.

J Exp Med 2006 Dec 11;203(13):2865-77. Epub 2006 Dec 11.

Immunology Laboratory, Human Immunology Section, Vaccine Research Center, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1084/jem.20052246DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118179PMC
December 2006

Polyfunctional analysis of human t cell responses: importance in vaccine immunogenicity and natural infection.

Springer Semin Immunopathol 2006 Nov 25;28(3):209-19. Epub 2006 Aug 25.

Department of Microbiology, University of Pennsylvania, Philadelphia, PA, USA.

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http://link.springer.com/10.1007/s00281-006-0025-4
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http://dx.doi.org/10.1007/s00281-006-0025-4DOI Listing
November 2006

Quantum dot semiconductor nanocrystals for immunophenotyping by polychromatic flow cytometry.

Nat Med 2006 Aug 23;12(8):972-7. Epub 2006 Jul 23.

Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, 40 Convent Drive, Bethesda, Maryland 20892, USA.

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http://dx.doi.org/10.1038/nm1371DOI Listing
August 2006

Antigen-specific T-cell-mediated immunity after HIV-1 infection: implications for vaccine control of HIV development.

Expert Rev Vaccines 2006 Aug;5(4):505-16

University of Pennsylvania, Department of Microbiology, 522E Johnson Pavilion, 3610 Hamilton Walk, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1586/14760584.5.4.505DOI Listing
August 2006

HIV nonprogressors preferentially maintain highly functional HIV-specific CD8+ T cells.

Blood 2006 Jun 7;107(12):4781-9. Epub 2006 Feb 7.

Immunology Laboratory, Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1182/blood-2005-12-4818DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1895811PMC
June 2006

Avidity for antigen shapes clonal dominance in CD8+ T cell populations specific for persistent DNA viruses.

J Exp Med 2005 Nov 14;202(10):1349-61. Epub 2005 Nov 14.

Human Immunology Section, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1084/jem.20051357DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212993PMC
November 2005

Detection of T-cell degranulation: CD107a and b.

Methods Cell Biol 2004 ;75:497-512

Immunology Laboratory, Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA.

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March 2005

The functional profile of primary human antiviral CD8+ T cell effector activity is dictated by cognate peptide concentration.

J Immunol 2004 May;172(10):6407-17

Immunology Laboratory, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.4049/jimmunol.172.10.6407DOI Listing
May 2004

Immediate cytotoxicity but not degranulation distinguishes effector and memory subsets of CD8+ T cells.

J Exp Med 2004 Apr 29;199(7):925-36. Epub 2004 Mar 29.

Institute for Microbiology, Eidgenössische Technische Hochschule Zurich, Schmelzbergstrasse 7, 8092, Switzerland.

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http://www.jem.org/lookup/doi/10.1084/jem.20031799
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http://dx.doi.org/10.1084/jem.20031799DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2211884PMC
April 2004

Flow cytometric analysis of vaccine responses: how many colors are enough?

Clin Immunol 2004 Mar;110(3):199-205

ImmunoTechnology Section, Vaccine Research Center, NIAID, NIH, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1016/j.clim.2003.11.015DOI Listing
March 2004

Ex vivo identification, isolation and analysis of tumor-cytolytic T cells.

Nat Med 2003 Nov 5;9(11):1377-82. Epub 2003 Oct 5.

Department of Medicine, Stanford University, 269 Campus Drive, Stanford, California 94305, USA.

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http://dx.doi.org/10.1038/nm942DOI Listing
November 2003

Toll-like receptor ligands modulate dendritic cells to augment cytomegalovirus- and HIV-1-specific T cell responses.

J Immunol 2003 Oct;171(8):4320-8

Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892-3022, USA.

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http://dx.doi.org/10.4049/jimmunol.171.8.4320DOI Listing
October 2003

Sensitive and viable identification of antigen-specific CD8+ T cells by a flow cytometric assay for degranulation.

J Immunol Methods 2003 Oct;281(1-2):65-78

Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, 40 Convent Drive, Bethesda, MD 20892, USA.

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October 2003

Prime-boost vaccination with HIV-1 Gag protein and cytosine phosphate guanosine oligodeoxynucleotide, followed by adenovirus, induces sustained and robust humoral and cellular immune responses.

J Immunol 2003 Sep;171(5):2538-47

Cellular Immunology Section, National Institute of Allergy and Infectious Diseases, National Institutes of Health, 40 Convent Drive, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.4049/jimmunol.171.5.2538DOI Listing
September 2003

Expression of CD57 defines replicative senescence and antigen-induced apoptotic death of CD8+ T cells.

Blood 2003 Apr 14;101(7):2711-20. Epub 2002 Nov 14.

Vaccine Research Center and the Laboratory of Immunoregulation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.

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http://www.bloodjournal.org/content/101/7/2711.full.pdf
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http://www.bloodjournal.org/cgi/doi/10.1182/blood-2002-07-21
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http://dx.doi.org/10.1182/blood-2002-07-2103DOI Listing
April 2003