Publications by authors named "Michael Palladino"

79Publications

The diagnostic value of Red Flags in thoracolumbar pain: a systematic review.

Disabil Rehabil 2020 Aug 19:1-17. Epub 2020 Aug 19.

Department of Neurosciences, Rehabilitation, Ophthalmology, Genetic and Maternal Infantile Sciences (DINOGMI), University of Genoa - Campus of Savona, Savona, Italy.

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http://dx.doi.org/10.1080/09638288.2020.1804626DOI Listing
August 2020

Rivaroxaban Versus Warfarin in African American Patients with Nonvalvular Atrial Fibrillation.

J Natl Med Assoc 2020 Aug 31;112(4):395-401. Epub 2020 May 31.

Department of Pharmacoepidemiology, New England Health Analytics LLC, Granby, CT, USA.

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http://dx.doi.org/10.1016/j.jnma.2020.04.014DOI Listing
August 2020

Chemical Targeting of Voltage Sensitive Dyes to Specific Cells and Molecules in the Brain.

J Am Chem Soc 2020 May 12;142(20):9285-9301. Epub 2020 May 12.

Department of Chemistry, Columbia University, New York, New York 10027, United States.

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http://dx.doi.org/10.1021/jacs.0c00861DOI Listing
May 2020

Rivaroxaban versus warfarin for treatment and prevention of recurrence of venous thromboembolism in African American patients: a retrospective cohort analysis.

Thromb J 2020 8;18. Epub 2020 Apr 8.

1Department of Pharmacy Practice, University of Connecticut School of Pharmacy, 69 North Eagleville Road, Unit 3092, Storrs, CT 06269 USA.

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http://dx.doi.org/10.1186/s12959-020-00219-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7140368PMC
April 2020

Stepping up to leadership.

Science 2020 Mar;367(6485):1494

Michael Palladino is a former vice provost for graduate studies at Monmouth University in New Jersey. In May, he'll be vice president for academic affairs and dean of the faculty at Bloomfield College.

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http://dx.doi.org/10.1126/science.367.6485.1494DOI Listing
March 2020

Missense variant in TPI1 (Arg189Gln) causes neurologic deficits through structural changes in the triosephosphate isomerase catalytic site and reduced enzyme levels in vivo.

Biochim Biophys Acta Mol Basis Dis 2019 09 7;1865(9):2257-2266. Epub 2019 May 7.

Department of Pharmacology & Chemical Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA; Pittsburgh Institute for Neurodegenerative Diseases (PIND), University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA. Electronic address:

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http://dx.doi.org/10.1016/j.bbadis.2019.05.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6659405PMC
September 2019

Sleep and circadian defects in a model of mitochondrial encephalomyopathy.

Neurobiol Sleep Circadian Rhythms 2019 Jan 4;6:44-52. Epub 2019 Feb 4.

Department of Pharmacology & Chemical Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.

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http://dx.doi.org/10.1016/j.nbscr.2019.01.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6411073PMC
January 2019

Ketogenic and anaplerotic dietary modifications ameliorate seizure activity in Drosophila models of mitochondrial encephalomyopathy and glycolytic enzymopathy.

Mol Genet Metab 2019 04 17;126(4):439-447. Epub 2019 Jan 17.

Department of Pharmacology & Chemical Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA; Pittsburgh Institute for Neurodegenerative Diseases (PIND), University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA.

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http://dx.doi.org/10.1016/j.ymgme.2019.01.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6536302PMC
April 2019

Molecular Neuroprotection Induced by Zinc-Dependent Expression of Hepatitis C-Derived Protein NS5A Targeting Kv2.1 Potassium Channels.

J Pharmacol Exp Ther 2018 11 6;367(2):348-355. Epub 2018 Sep 6.

Departments of Neurobiology (J.A.J., C.-Y.Y., K.A.H.-S., A.J.S., G.J.K., S.M., E.A.) and Pharmacology and Chemical Biology (D.T.M., M.J.P.) and Pittsburgh Institute for Neurodegenerative Diseases (J.A.J., D.T.M., C.-Y.Y., K.A.H.-S., A.J.S., G.J.K., S.M., M.J.P., E.A.), University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania

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http://dx.doi.org/10.1124/jpet.118.252338DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6193254PMC
November 2018

Mutational analysis implicates the amyloid fibril as the toxic entity in Huntington's disease.

Neurobiol Dis 2018 12 30;120:126-138. Epub 2018 Aug 30.

Department of Structural Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15260, USA; Pittsburgh Institute for Neurodegenerative Diseases (PIND), University of Pittsburgh School of Medicine, Pittsburgh, PA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.nbd.2018.08.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6186178PMC
December 2018

Protein coding mitochondrial-targeted RNAs rescue mitochondrial disease in vivo.

Neurobiol Dis 2018 09 13;117:203-210. Epub 2018 Jun 13.

Department of Pharmacology & Chemical Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA; Pittsburgh Institute for Neurodegenerative Diseases (PIND), University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA. Electronic address:

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http://dx.doi.org/10.1016/j.nbd.2018.06.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6082375PMC
September 2018

MicroRNAs downregulated following immune activation of rat testis.

Am J Reprod Immunol 2017 06 22;77(6). Epub 2017 Mar 22.

Monmouth University, West Long Branch, NJ, USA.

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http://dx.doi.org/10.1111/aji.12673DOI Listing
June 2017

The ATP-sensitive K channel is seizure protective and required for effective dietary therapy in a model of mitochondrial encephalomyopathy.

J Neurogenet 2016 Sep - Dec;30(3-4):247-258. Epub 2016 Nov 21.

a Department of Pharmacology & Chemical Biology , University of Pittsburgh School of Medicine , Pittsburgh , PA , USA.

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http://dx.doi.org/10.1080/01677063.2016.1252765DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5590012PMC
December 2017

Cost of surviving sepsis: a novel model of recovery from sepsis in Drosophila melanogaster.

Intensive Care Med Exp 2016 Dec 21;4(1). Epub 2016 Jan 21.

Clinical Research, Investigation, and Systems Modeling of Acute Illness (CRISMA) Laboratory, Department of Critical Care Medicine, University of Pittsburgh School of Medicine, 612 Scaife Hall, 3550 Terrace Street, Pittsburgh, 15261, PA, USA.

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http://dx.doi.org/10.1186/s40635-016-0075-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4720623PMC
December 2016

Genome-wide screen for modifiers of Na (+) /K (+) ATPase alleles identifies critical genetic loci.

Mol Brain 2014 Dec 5;7:89. Epub 2014 Dec 5.

Department of Pharmacology & Chemical Biology, University of Pittsburgh School of Medicine, 3501 Fifth Avenue, BST3 7042, Pittsburgh, PA, 15261, USA.

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http://dx.doi.org/10.1186/s13041-014-0089-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4302446PMC
December 2014

Triosephosphate isomerase I170V alters catalytic site, enhances stability and induces pathology in a Drosophila model of TPI deficiency.

Biochim Biophys Acta 2015 Jan 16;1852(1):61-9. Epub 2014 Oct 16.

Department of Pharmacology & Chemical Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA; Pittsburgh Institute for Neurodegenerative Diseases (PIND), University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA. Electronic address:

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http://dx.doi.org/10.1016/j.bbadis.2014.10.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4268122PMC
January 2015

Anti-inflammatory actions of acanthoic acid-related diterpenes involve activation of the PI3K p110γ/δ subunits and inhibition of NF-κB.

Chem Biol 2014 Aug 24;21(8):955-66. Epub 2014 Jul 24.

Instituto de Investigaciones Biomédicas Alberto Sols, Centro Mixto CSIC-UAM, Unidad Asociada Universidad de las Palmas de Gran Canaria, Arturo Duperier 4, 28029 Madrid, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.chembiol.2014.06.005DOI Listing
August 2014

Genetically encoded redox sensors.

Methods Enzymol 2014 ;542:263-87

Department of Pharmacology & Chemical Biology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA; Pittsburgh Institute for Neurodegenerative Diseases, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA. Electronic address:

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http://dx.doi.org/10.1016/B978-0-12-416618-9.00014-5DOI Listing
May 2015

Small mitochondrial-targeted RNAs modulate endogenous mitochondrial protein expression in vivo.

Neurobiol Dis 2014 Sep 5;69:15-22. Epub 2014 May 5.

Department of Pharmacology & Chemical Biology, University of Pittsburgh School of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA; Pittsburgh Institute for Neurodegenerative Diseases (PIND), University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA. Electronic address:

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http://dx.doi.org/10.1016/j.nbd.2014.04.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4106415PMC
September 2014

Evaluation of the oral direct factor Xa inhibitor - betrixaban.

Expert Opin Investig Drugs 2013 Nov 22;22(11):1465-72. Epub 2013 Aug 22.

Thomas Jefferson University Hospital, Department of Pharmacy - Vascular Medicine , 111 South 10th St, Philadelphia, PA 19107 , USA +1609 706 5271 ;

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http://dx.doi.org/10.1517/13543784.2013.825605DOI Listing
November 2013

Evidence of a triosephosphate isomerase non-catalytic function crucial to behavior and longevity.

J Cell Sci 2013 Jul 2;126(Pt 14):3151-8. Epub 2013 May 2.

Department of Pharmacology and Chemical Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA.

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http://dx.doi.org/10.1242/jcs.124586DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3711204PMC
July 2013

Early mitochondrial dysfunction leads to altered redox chemistry underlying pathogenesis of TPI deficiency.

Neurobiol Dis 2013 Jun 12;54:289-96. Epub 2013 Jan 12.

Deparment of Pharmacology & Chemical Biology, University of Pittsburgh Medical School, Pittsburgh, PA 15261, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S09699961130001
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http://dx.doi.org/10.1016/j.nbd.2012.12.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3628936PMC
June 2013

Myeloid cell leukemia-1 (Mc1-1) is a candidate target gene of hypoxia-inducible factor-1 (HIF-1) in the testis.

Reprod Biol Endocrinol 2012 Dec 5;10:104. Epub 2012 Dec 5.

Department of Biology, Monmouth University, 400 Cedar Avenue, West Long Branch, NJ 07764, USA.

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http://dx.doi.org/10.1186/1477-7827-10-104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3556106PMC
December 2012

Synthesis and structure-activity relationships of benzophenone-bearing diketopiperazine-type anti-microtubule agents.

Bioorg Med Chem 2012 Jul 4;20(14):4279-89. Epub 2012 Jun 4.

Department of Medicinal Chemistry, Tokyo University of Pharmacy and Life Sciences, Hachioji, Tokyo 192-0392, Japan.

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http://dx.doi.org/10.1016/j.bmc.2012.05.059DOI Listing
July 2012

Implementing the new oral anticoagulants into the hospital formulary.

Am J Hematol 2012 May 12;87 Suppl 1:S127-32. Epub 2012 Apr 12.

Thomas Jefferson University Hospitals, Jefferson Medical College, Philadelphia, Pennsylvania 19107, USA.

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http://doi.wiley.com/10.1002/ajh.23208
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http://dx.doi.org/10.1002/ajh.23208DOI Listing
May 2012

Trypanocidal activity of β-lactone-γ-lactam proteasome inhibitors.

Planta Med 2012 Jan 27;78(2):131-4. Epub 2011 Oct 27.

BioMedical Research Centre, Norwich Medical School, University of East Anglia, Norwich, UK.

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http://www.thieme-connect.de/DOI/DOI?10.1055/s-0031-1280315
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http://dx.doi.org/10.1055/s-0031-1280315DOI Listing
January 2012

Modes of metabolic compensation during mitochondrial disease using the Drosophila model of ATP6 dysfunction.

PLoS One 2011 3;6(10):e25823. Epub 2011 Oct 3.

Department of Pharmacology and Chemical Biology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0025823PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3185040PMC
February 2012

Genetically encoded redox sensor identifies the role of ROS in degenerative and mitochondrial disease pathogenesis.

Neurobiol Dis 2012 Jan 25;45(1):362-8. Epub 2011 Aug 25.

Department of Pharmacology & Chemical Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA.

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http://dx.doi.org/10.1016/j.nbd.2011.08.022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3225579PMC
January 2012

Specific and prolonged proteasome inhibition dictates apoptosis induction by marizomib and its analogs.

Chem Biol Interact 2011 Oct 16;194(1):58-68. Epub 2011 Aug 16.

Department of Pediatrics Research, Children's Cancer Hospital at M.D. Anderson, University of Texas M.D. Anderson Cancer Center, Houston, United States.

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http://dx.doi.org/10.1016/j.cbi.2011.08.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3186881PMC
October 2011

A novel vascular disrupting agent plinabulin triggers JNK-mediated apoptosis and inhibits angiogenesis in multiple myeloma cells.

Blood 2011 May 31;117(21):5692-700. Epub 2011 Mar 31.

Jerome Lipper Multiple Myeloma Center, Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1182/blood-2010-12-323857DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3110026PMC
May 2011

New oral anticoagulants.

J Thromb Thrombolysis 2011 Apr;31(3):310-20

Jefferson Medical College, Thomas Jefferson University Hospitals, Jefferson Vascular Center, Suite 6270, Gibbon Building, 111 South 11th Street, Philadelphia, PA 19107, USA.

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http://dx.doi.org/10.1007/s11239-011-0559-8DOI Listing
April 2011

Hsp70- and Hsp90-mediated proteasomal degradation underlies TPI sugarkill pathogenesis in Drosophila.

Neurobiol Dis 2010 Dec 19;40(3):676-83. Epub 2010 Aug 19.

Deparment of Pharmacology & Chemical Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA.

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http://dx.doi.org/10.1016/j.nbd.2010.08.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2955819PMC
December 2010

Modeling mitochondrial encephalomyopathy in Drosophila.

Neurobiol Dis 2010 Oct 21;40(1):40-5. Epub 2010 May 21.

Deparment of Pharmacology & Chemical Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA.

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http://dx.doi.org/10.1016/j.nbd.2010.05.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2926304PMC
October 2010

Pharmacodynamic and efficacy studies of the novel proteasome inhibitor NPI-0052 (marizomib) in a human plasmacytoma xenograft murine model.

Br J Haematol 2010 May 12;149(4):550-9. Epub 2010 Mar 12.

The LeBow Institute for Myeloma Therapeutics and Jerome Lipper Myeloma Center, Department of Medical Oncology, Dana Farber Cancer Institute, Harvard Medical School, Boston, MA 02115, USA.

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http://dx.doi.org/10.1111/j.1365-2141.2010.08144.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4427841PMC
May 2010

Combination of novel proteasome inhibitor NPI-0052 and lenalidomide trigger in vitro and in vivo synergistic cytotoxicity in multiple myeloma.

Blood 2010 Jan 13;115(4):834-45. Epub 2009 Nov 13.

LeBow Institute for Myeloma Therapeutics and Jerome Lipper Myeloma Center, Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1182/blood-2009-03-213009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2815518PMC
January 2010

Pivotal roles of snail inhibition and RKIP induction by the proteasome inhibitor NPI-0052 in tumor cell chemoimmunosensitization.

Cancer Res 2009 Nov 20;69(21):8376-85. Epub 2009 Oct 20.

Department of Microbiology, Jonsson Comprehensive Cancer Center, David Geffen School of Medicine, University of California at Los Angeles, California 90095-736422, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-09-1069DOI Listing
November 2009

Novel mutations affecting the Na, K ATPase alpha model complex neurological diseases and implicate the sodium pump in increased longevity.

Hum Genet 2009 Sep 12;126(3):431-47. Epub 2009 May 12.

Department of Pharmacology & Chemical Biology, Pittsburgh Institute for Neurodegenerative Diseases, University of Pittsburgh School of Medicine, 3501 Fifth Ave., BST3 7042, Pittsburgh, PA 15260, USA.

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http://dx.doi.org/10.1007/s00439-009-0673-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2791699PMC
September 2009

Caspase-8 dependent histone acetylation by a novel proteasome inhibitor, NPI-0052: a mechanism for synergy in leukemia cells.

Blood 2009 Apr 30;113(18):4289-99. Epub 2009 Jan 30.

Department of Pediatrics Research, University of Texas M D Anderson Cancer Center, Houston, TX, USA.

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http://dx.doi.org/10.1182/blood-2008-08-174797DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2676087PMC
April 2009

Localization of Toll-like receptors on epididymal epithelial cells and spermatozoa.

Am J Reprod Immunol 2008 Dec;60(6):541-55

Biology Department, Monmouth University, West Long Branch, NJ 07764, USA.

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http://dx.doi.org/10.1111/j.1600-0897.2008.00654.xDOI Listing
December 2008

Discovery and development of the anticancer agent salinosporamide A (NPI-0052).

Bioorg Med Chem 2009 Mar 5;17(6):2175-80. Epub 2008 Nov 5.

Center for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography, University of California, San Diego, La Jolla, CA 92093-0204, USA.

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http://dx.doi.org/10.1016/j.bmc.2008.10.075DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2814440PMC
March 2009

Cleavage of mispaired heteroduplex DNA substrates by numerous restriction enzymes.

Curr Issues Mol Biol 2009 19;11(1):1-12. Epub 2008 May 19.

Department of Pharmacology and Chemical Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2670344PMC
June 2009

Degradation of functional triose phosphate isomerase protein underlies sugarkill pathology.

Genetics 2008 Jun 5;179(2):855-62. Epub 2008 May 5.

Department of Pharmacology and Chemical Biology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15261, USA.

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http://dx.doi.org/10.1534/genetics.108.087551DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2429879PMC
June 2008

Inhibition of Yin Yang 1-dependent repressor activity of DR5 transcription and expression by the novel proteasome inhibitor NPI-0052 contributes to its TRAIL-enhanced apoptosis in cancer cells.

J Immunol 2008 May;180(9):6199-210

Department of Microbiology, Immunology, and Molecular Genetics, Division of Surgical Oncology, David Geffen School of Medicine, University of California-Los Angeles, 10833 Le Conte Avenue, Los Angeles, CA 90095, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3747671PMC
http://dx.doi.org/10.4049/jimmunol.180.9.6199DOI Listing
May 2008

Neuropathology in Drosophila mutants with increased seizure susceptibility.

Genetics 2008 Feb 1;178(2):947-56. Epub 2008 Feb 1.

Laboratory of Genetics, University of Wisconsin, Madison, Wisconsin 53706, USA.

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http://dx.doi.org/10.1534/genetics.107.082115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2248337PMC
February 2008

Combination of proteasome inhibitors bortezomib and NPI-0052 trigger in vivo synergistic cytotoxicity in multiple myeloma.

Blood 2008 Feb 15;111(3):1654-64. Epub 2007 Nov 15.

The LeBow Institute for Myeloma Therapeutics and Jerome Lipper Center for Myeloma Research, Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02115, USA.

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http://dx.doi.org/10.1182/blood-2007-08-105601DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2214767PMC
February 2008

Salinosporamide A (NPI-0052) potentiates apoptosis, suppresses osteoclastogenesis, and inhibits invasion through down-modulation of NF-kappaB regulated gene products.

Blood 2007 Oct 3;110(7):2286-95. Epub 2007 Jul 3.

Cytokine Research Laboratory, Department of Experimental Therapeutics, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA.

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http://dx.doi.org/10.1182/blood-2007-04-084996DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1988928PMC
October 2007

Selective activation of liver X receptors by acanthoic acid-related diterpenes.

Mol Pharmacol 2007 Jun 28;71(6):1545-53. Epub 2007 Feb 28.

Centro Nacional de Investigaciones Cardiovasculares and Instituto de Investigaciones Biomédicas Alberto Sols, Madrid, Spain.

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http://molpharm.aspetjournals.org/content/early/2007/02/28/m
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http://molpharm.aspetjournals.org/cgi/doi/10.1124/mol.106.03
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http://dx.doi.org/10.1124/mol.106.031906DOI Listing
June 2007

A pump-independent function of the Na,K-ATPase is required for epithelial junction function and tracheal tube-size control.

Development 2007 Jan;134(1):147-55

Department of Biochemistry, Molecular Biology and Cell Biology, Northwestern University, Evanston, IL 60208, USA.

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http://dx.doi.org/10.1242/dev.02710DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1955469PMC
January 2007

NPI-0052 enhances tumoricidal response to conventional cancer therapy in a colon cancer model.

Clin Cancer Res 2006 Nov;12(22):6758-64

Division of Surgical Oncology, Massachusetts General Hospital, Harvard Medical School, Boston 02114, USA.

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http://dx.doi.org/10.1158/1078-0432.CCR-06-1151DOI Listing
November 2006

Drosophila model of human inherited triosephosphate isomerase deficiency glycolytic enzymopathy.

Genetics 2006 Nov 15;174(3):1237-46. Epub 2006 Sep 15.

Department of Pharmacology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15261, USA.

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http://dx.doi.org/10.1534/genetics.106.063206DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1667072PMC
November 2006

The proteasome inhibitor NPI-0052 is a more effective inducer of apoptosis than bortezomib in lymphocytes from patients with chronic lymphocytic leukemia.

Mol Cancer Ther 2006 Jul;5(7):1836-43

Department of Cancer Biology, The University of Texas M.D. Anderson Cancer Center, Box 173, 1515 Holcombe Boulevard, Houston, TX 77030, USA.

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http://dx.doi.org/10.1158/1535-7163.MCT-06-0066DOI Listing
July 2006

Mitochondrial encephalomyopathy in Drosophila.

J Neurosci 2006 Jan;26(3):810-20

Department of Pharmacology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15261, USA.

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http://dx.doi.org/10.1523/JNEUROSCI.4162-05.2006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6675365PMC
January 2006

Neuropathology in Drosophila membrane excitability mutants.

Genetics 2006 Feb 4;172(2):1031-42. Epub 2005 Nov 4.

Laboratory of Genetics, University of Wisconsin, Madison 53706, USA.

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http://dx.doi.org/10.1534/genetics.105.050625DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1456203PMC
February 2006

Drosophila: a "model" model system to study neurodegeneration.

Mol Interv 2005 Oct;5(5):292-303

Department of Pharmacology and Pittsburgh Institute for Neurodegenerative Diseases, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA.

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http://dx.doi.org/10.1124/mi.5.5.9DOI Listing
October 2005

Anti-TNF-alpha therapies: the next generation.

Nat Rev Drug Discov 2003 Sep;2(9):736-46

Nereus Pharmaceuticals, 10480 Wateridge Circle, San Diego, California 92121, USA.

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http://dx.doi.org/10.1038/nrd1175DOI Listing
September 2003

Synthesis of a novel family of diterpenes and their evaluation as anti-inflammatory agents.

Bioorg Med Chem Lett 2003 Oct;13(19):3217-21

Department of Chemistry and Biochemistry, University of California-San Diego, 9500 Gilman Drive, La Jolla, CA 92093-0358, USA.

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http://theodorakisgroup.ucsd.edu/publications%20folder/2000-
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http://dx.doi.org/10.1016/s0960-894x(03)00669-3DOI Listing
October 2003

Neural dysfunction and neurodegeneration in Drosophila Na+/K+ ATPase alpha subunit mutants.

J Neurosci 2003 Feb;23(4):1276-86

Laboratory of Genetics, University of Wisconsin, Madison, Wisconsin 53706, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6742270PMC
February 2003

Temperature-sensitive paralytic mutants are enriched for those causing neurodegeneration in Drosophila.

Genetics 2002 Jul;161(3):1197-208

Laboratory of Genetics, University of Wisconsin, Madison, WI 53706, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1462168PMC
July 2002