Michael P Walsh

Michael P Walsh

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Michael P Walsh

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Expression of troponin subunits in the rat renal afferent arteriole.

IUBMB Life 2019 Oct 2;71(10):1475-1481. Epub 2019 May 2.

Department of Biochemistry and Molecular Biology, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.

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http://dx.doi.org/10.1002/iub.2061DOI Listing
October 2019

Regulation of Smooth Muscle Myosin Light Chain Phosphatase by Multisite Phosphorylation of the Myosin Targeting Subunit, MYPT1.

Cardiovasc Hematol Disord Drug Targets 2018 ;18(1):4-13

Department of Biochemistry & Molecular Biology, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.

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http://dx.doi.org/10.2174/1871529X18666180326120638DOI Listing
March 2019

Validation of chemical genetics for the study of zipper-interacting protein kinase signaling.

Proteins 2018 11 1;86(11):1211-1217. Epub 2018 Nov 1.

Department of Biochemistry & Molecular Biology, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.

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http://doi.wiley.com/10.1002/prot.25607
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http://dx.doi.org/10.1002/prot.25607DOI Listing
November 2018

Abnormal myosin phosphatase targeting subunit 1 phosphorylation and actin polymerization contribute to impaired myogenic regulation of cerebral arterial diameter in the type 2 diabetic Goto-Kakizaki rat.

J Cereb Blood Flow Metab 2017 01 31;37(1):227-240. Epub 2015 Dec 31.

The Smooth Muscle Research Group, Departments of Physiology & Pharmacology, Libin Cardiovascular Institute & Hotchkiss Brain Institute, Cumming School of Medicine, University of Calgary, Alberta, Canada

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http://dx.doi.org/10.1177/0271678X15622463DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5363741PMC
January 2017

On-road vehicle emissions and their control in China: A review and outlook.

Sci Total Environ 2017 Jan 14;574:332-349. Epub 2016 Oct 14.

International Laboratory for Air Quality and Health, Queensland University of Technology, Brisbane, Queensland 4001, Australia.

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http://dx.doi.org/10.1016/j.scitotenv.2016.09.040DOI Listing
January 2017

A novel inhibitory effect of oxazol-5-one compounds on ROCKII signaling in human coronary artery vascular smooth muscle cells.

Sci Rep 2016 08 30;6:32118. Epub 2016 Aug 30.

Department of Biochemistry &Molecular Biology, University of Calgary, 3280 Hospital Drive NW, Calgary, AB, T2N 4Z6, Canada.

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http://dx.doi.org/10.1038/srep32118DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5004178PMC
August 2016

Analysis of phosphorylation of the myosin-targeting subunit of myosin light chain phosphatase by Phos-tag SDS-PAGE.

Am J Physiol Cell Physiol 2016 04 10;310(8):C681-91. Epub 2016 Feb 10.

Department of Biochemistry and Molecular Biology, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada

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http://www.physiology.org/doi/10.1152/ajpcell.00327.2015
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http://dx.doi.org/10.1152/ajpcell.00327.2015DOI Listing
April 2016

Potential Role of Glycogen Synthase Kinase-3β in Regulation of Myocardin Activity in Human Vascular Smooth Muscle Cells.

J Cell Physiol 2016 Feb;231(2):393-402

Department of Biochemistry and Molecular Biology, Smooth Muscle Research Group, Libin Cardiovascular Institute of Alberta, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.

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http://dx.doi.org/10.1002/jcp.25084DOI Listing
February 2016

A Small Molecule Pyrazolo[3,4-d]Pyrimidinone Inhibitor of Zipper-Interacting Protein Kinase Suppresses Calcium Sensitization of Vascular Smooth Muscle.

Mol Pharmacol 2016 Jan 13;89(1):105-17. Epub 2015 Oct 13.

Department of Biochemistry and Molecular Biology, University of Calgary, Cumming School of Medicine, Calgary, Alberta, Canada (J.A.M., C.S., S.B., A.A.-G., M.P.W.); Department of Experimental Medical Science, Lund University, Lund, Sweden (K.S.); and Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, North Carolina (D.A.C., T.A.J.H.).

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http://dx.doi.org/10.1124/mol.115.100529DOI Listing
January 2016

A role for the Ca(2+)-dependent tyrosine kinase Pyk2 in tonic depolarization-induced vascular smooth muscle contraction.

J Muscle Res Cell Motil 2015 Dec 7;36(6):479-89. Epub 2015 Jul 7.

Smooth Muscle Research Group and Department of Biochemistry and Molecular Biology, Cumming School of Medicine, University of Calgary, 3330 Hospital Drive N.W., Calgary, AB, T2N 4N1, Canada.

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http://dx.doi.org/10.1007/s10974-015-9416-2DOI Listing
December 2015

The effects of knockdown of rho-associated kinase 1 and zipper-interacting protein kinase on gene expression and function in cultured human arterial smooth muscle cells.

PLoS One 2015 27;10(2):e0116969. Epub 2015 Feb 27.

Smooth Muscle Research Group and Department of Biochemistry and Molecular Biology, University of Calgary, Alberta, Canada; Hotchkiss Brain Institute and Libin Cardiovascular Institute of Alberta, University of Calgary, Alberta, Canada.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0116969PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4344299PMC
November 2015

α5-Integrin-mediated cellular signaling contributes to the myogenic response of cerebral resistance arteries.

Biochem Pharmacol 2015 Oct 14;97(3):281-91. Epub 2015 Aug 14.

Smooth Muscle Research Group, Department of Physiology and Pharmacology, Hotchkiss Brain Institute and Libin Cardiovascular Institute, University of Calgary, Alberta, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.bcp.2015.08.088DOI Listing
October 2015

The GPER agonist G-1 induces mitotic arrest and apoptosis in human vascular smooth muscle cells independent of GPER.

J Cell Physiol 2015 Apr;230(4):885-95

The Smooth Muscle Research Group, Department of Physiology and Pharmacology, Libin Cardiovascular Institute of Alberta, University of Calgary, Calgary, Alberta, Canada.

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http://dx.doi.org/10.1002/jcp.24817DOI Listing
April 2015

A role for the tyrosine kinase Pyk2 in depolarization-induced contraction of vascular smooth muscle.

J Biol Chem 2015 Apr 24;290(14):8677-92. Epub 2015 Feb 24.

From the Smooth Muscle Research Group, Department of Biochemistry and Molecular Biology, Libin Cardiovascular Institute and Hotchkiss Brain Institute, University of Calgary, Calgary, Alberta T2N 4N1, Canada and

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http://dx.doi.org/10.1074/jbc.M114.633107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4423659PMC
April 2015

Abnormal Rho-associated kinase activity contributes to the dysfunctional myogenic response of cerebral arteries in type 2 diabetes.

Can J Physiol Pharmacol 2015 Mar 12;93(3):177-84. Epub 2015 Jan 12.

The Smooth Muscle Research Group, Libin Cardiovascular Institute, Hotchkiss Brain Institute, and the Department of Physiology & Pharmacology, Cumming School of Medicine, University of Calgary, 3330 Hospital Drive NW, Calgary, AB T2N 4N1, Canada.

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http://www.nrcresearchpress.com/doi/10.1139/cjpp-2014-0437
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http://dx.doi.org/10.1139/cjpp-2014-0437DOI Listing
March 2015

Endothelin-1, but not angiotensin II, induces afferent arteriolar myosin diphosphorylation as a potential contributor to prolonged vasoconstriction.

Kidney Int 2015 Feb 20;87(2):370-81. Epub 2014 Aug 20.

Smooth Muscle Research Group and Department of Biochemistry and Molecular Biology, Faculty of Medicine, University of Calgary, Calgary, Alberta, Canada.

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http://dx.doi.org/10.1038/ki.2014.284DOI Listing
February 2015

The PRKCI and SOX2 oncogenes are coamplified and cooperate to activate Hedgehog signaling in lung squamous cell carcinoma.

Cancer Cell 2014 Feb;25(2):139-51

Department of Cancer Biology, Mayo Clinic Cancer Center, Jacksonville, FL 32224, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccr.2014.01.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3949484PMC
February 2014

Structural analysis of a calmodulin variant from rice: the C-terminal extension of OsCaM61 regulates its calcium binding and enzyme activation properties.

J Biol Chem 2013 Nov 19;288(44):32036-49. Epub 2013 Sep 19.

From the Department of Biological Sciences, University of Calgary, Calgary, Alberta T2N 1N4, Canada and.

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http://dx.doi.org/10.1074/jbc.M113.491076DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3814798PMC
November 2013

Kinetics of myosin light chain kinase activation of smooth muscle myosin in an in vitro model system.

Biochemistry 2013 Nov 11;52(47):8489-500. Epub 2013 Nov 11.

Department of Biochemistry and Molecular Biology, University of Nevada School of Medicine , Reno, Nevada 99557, United States.

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http://dx.doi.org/10.1021/bi401001xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3886827PMC
November 2013

Computational analysis of four human adenovirus type 4 genomes reveals molecular evolution through two interspecies recombination events.

Virology 2013 Sep 10;443(2):197-207. Epub 2013 Jun 10.

Chemistry Department, American University, Washington, D.C. 20016, USA; Bioinformatics and Computational Biology Program, School of Systems Biology, George Mason University, Manassas, VA 20110, USA.

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http://dx.doi.org/10.1016/j.virol.2013.05.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3779658PMC
September 2013

Excess thermopower and the theory of thermopower waves.

ACS Nano 2013 Aug 7;7(8):6533-44. Epub 2013 Aug 7.

Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, United States.

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http://dx.doi.org/10.1021/nn402411kDOI Listing
August 2013

Prostate-apoptosis response-4 phosphorylation in vascular smooth muscle.

Arch Biochem Biophys 2013 Jul 3;535(1):84-90. Epub 2012 Dec 3.

Smooth Muscle Research Group and Department of Biochemistry & Molecular Biology, University of Calgary, 3280 Hospital Drive NW, Calgary, AB, Canada T2N 4Z6.

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http://dx.doi.org/10.1016/j.abb.2012.11.009DOI Listing
July 2013

Uridine adenosine tetraphosphate induces contraction of circular and longitudinal gastric smooth muscle by distinct signaling pathways.

IUBMB Life 2013 Jul 14;65(7):623-32. Epub 2013 May 14.

Department of Biochemistry and Molecular Biology, School of Medicine, Nankai University, Tianjin, People' Republic of China.

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http://dx.doi.org/10.1002/iub.1171DOI Listing
July 2013

Predicting the next eye pathogen: analysis of a novel adenovirus.

MBio 2013 Apr 9;4(2):e00595-12. Epub 2013 Apr 9.

Department of Ophthalmology, Howe Laboratory, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1128/mBio.00595-12DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3622935PMC
April 2013

Ca2+ sensitization due to myosin light chain phosphatase inhibition and cytoskeletal reorganization in the myogenic response of skeletal muscle resistance arteries.

J Physiol 2013 Mar 10;591(5):1235-50. Epub 2012 Dec 10.

The Smooth Muscle Research Group, Department of Physiology and Pharmacology, Libin Cardiovascular Institute and Hotchkiss Brain Institute, Faculty of Medicine, University of Calgary, 3330 Hospital Drive N.W., Calgary, Alberta, Canada T2N 4N1.

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http://doi.wiley.com/10.1113/jphysiol.2012.243576
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http://dx.doi.org/10.1113/jphysiol.2012.243576DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3607868PMC
March 2013

The role of actin filament dynamics in the myogenic response of cerebral resistance arteries.

J Cereb Blood Flow Metab 2013 Jan 17;33(1):1-12. Epub 2012 Oct 17.

Smooth Muscle Research Group, Department of Biochemistry and Molecular Biology, Faculty of Medicine, University of Calgary, Calgary, Alberta, Canada.

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http://journals.sagepub.com/doi/10.1038/jcbfm.2012.144
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http://dx.doi.org/10.1038/jcbfm.2012.144DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3597360PMC
January 2013

Cross-talk between Rho-associated kinase and cyclic nucleotide-dependent kinase signaling pathways in the regulation of smooth muscle myosin light chain phosphatase.

J Biol Chem 2012 Oct 4;287(43):36356-69. Epub 2012 Sep 4.

Smooth Muscle Research Group and Libin Cardiovascular Institute of Alberta, University of Calgary, Calgary, Alberta T2N 4Z6, Canada.

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http://dx.doi.org/10.1074/jbc.M112.398479DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3476302PMC
October 2012

Atorvastatin inhibits myocardin expression in vascular smooth muscle cells.

Hypertension 2012 Jul 21;60(1):145-53. Epub 2012 May 21.

Department of Biochemistry and Molecular Biology, The Libin Cardiovascular Institute of Alberta, The University of Calgary, Health Sciences Center, 3330 Hospital Dr NW, Calgary, Alberta, Canada T2N 4N1.

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http://hyper.ahajournals.org/content/hypertensionaha/60/1/14
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http://hyper.ahajournals.org/cgi/doi/10.1161/HYPERTENSIONAHA
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http://dx.doi.org/10.1161/HYPERTENSIONAHA.112.195644DOI Listing
July 2012

Myosin regulatory light chain diphosphorylation slows relaxation of arterial smooth muscle.

J Biol Chem 2012 Jul 31;287(29):24064-76. Epub 2012 May 31.

Department of Biochemistry and Molecular Biology, Faculty of Medicine, University of Calgary, Calgary, Alberta T2N 4N1, Canada.

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http://dx.doi.org/10.1074/jbc.M112.371609DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3397833PMC
July 2012

Matrix metalloproteinase-2 proteolysis of calponin-1 contributes to vascular hypocontractility in endotoxemic rats.

Arterioscler Thromb Vasc Biol 2012 Mar 22;32(3):662-8. Epub 2011 Dec 22.

Department of Pharmacology, Cardiovascular Research Centre, Mazankowski Alberta Heart Institute, 4-62 Heritage Medical Research Centre, University of Alberta, Edmonton, Alberta, T6G 2S2, Canada.

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http://dx.doi.org/10.1161/ATVBAHA.111.242685DOI Listing
March 2012

Tissue length modulates "stimulated actin polymerization," force augmentation, and the rate of swine carotid arterial contraction.

Am J Physiol Cell Physiol 2011 Dec 24;301(6):C1470-8. Epub 2011 Aug 24.

Cardiovascular Division, University of Virginia Health System, Charlottesville, VA 22908-0146, USA.

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http://www.physiology.org/doi/10.1152/ajpcell.00149.2011
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http://dx.doi.org/10.1152/ajpcell.00149.2011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3233796PMC
December 2011

Signaling mechanisms mediating uridine adenosine tetraphosphate-induced proliferation of human vascular smooth muscle cells.

J Cardiovasc Pharmacol 2011 Dec;58(6):654-62

Smooth Muscle Research Group, Department of Physiology and Pharmacology, University of Calgary, Calgary, Alberta, Canada.

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http://dx.doi.org/10.1097/FJC.0b013e318231e929DOI Listing
December 2011

Uridine adenosine tetraphosphate induces contraction of airway smooth muscle.

Am J Physiol Lung Cell Mol Physiol 2011 Nov 12;301(5):L789-94. Epub 2011 Aug 12.

Dept. of Physiology & Pharmacology, Faculty of Medicine, Univ. of Calgary, 3330 Hospital Drive NW, Calgary, Alberta, Canada T2N 4N1.

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http://dx.doi.org/10.1152/ajplung.00203.2011DOI Listing
November 2011

Vascular smooth muscle myosin light chain diphosphorylation: mechanism, function, and pathological implications.

Authors:
Michael P Walsh

IUBMB Life 2011 Nov 12;63(11):987-1000. Epub 2011 Oct 12.

Smooth Muscle Research Group and Department of Biochemistry and Molecular Biology, University of Calgary, Calgary, Alberta T2N 4N1, Canada.

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http://doi.wiley.com/10.1002/iub.527
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http://dx.doi.org/10.1002/iub.527DOI Listing
November 2011

Do TRPC-like currents and G protein-coupled receptors interact to facilitate myogenic tone development?

Am J Physiol Heart Circ Physiol 2011 Oct 5;301(4):H1378-88. Epub 2011 Aug 5.

Department of Physiology and Pharmacology, Hotchkiss Brain and Libin Cardiovascular Institutes, University of Calgary, Alberta, Canada.

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http://dx.doi.org/10.1152/ajpheart.00460.2011DOI Listing
October 2011

The importance of Rho-associated kinase-induced Ca2+ sensitization as a component of electromechanical and pharmacomechanical coupling in rat ureteric smooth muscle.

Cell Calcium 2011 Oct 11;50(4):393-405. Epub 2011 Aug 11.

Department of Cellular and Molecular Physiology, Institute of Translational Medicine, University of Liverpool, Crown Street, Liverpool L69 3BX, UK.

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http://dx.doi.org/10.1016/j.ceca.2011.07.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3521031PMC
October 2011

Chemical genetics of zipper-interacting protein kinase reveal myosin light chain as a bona fide substrate in permeabilized arterial smooth muscle.

J Biol Chem 2011 Oct 31;286(42):36978-91. Epub 2011 Aug 31.

Smooth Muscle Research Group and the Department of Biochemistry and Molecular Biology, University of Calgary, Calgary, Alberta T2N 4Z6, Canada.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M111.257949
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http://dx.doi.org/10.1074/jbc.M111.257949DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3196122PMC
October 2011

The myosin phosphatase targeting protein (MYPT) family: a regulated mechanism for achieving substrate specificity of the catalytic subunit of protein phosphatase type 1δ.

Arch Biochem Biophys 2011 Jun 1;510(2):147-59. Epub 2011 Feb 1.

Smooth Muscle Research Group, Department of Biochemistry and Molecular Biology, University of Calgary, AB, Canada.

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http://dx.doi.org/10.1016/j.abb.2011.01.018DOI Listing
June 2011

Guest editorial & introduction to the special issue.

Arch Biochem Biophys 2011 Jun;510(2):73-5

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http://dx.doi.org/10.1016/j.abb.2011.06.001DOI Listing
June 2011

Rapamycin inhibits hydrogen peroxide-induced loss of vascular contractility.

Am J Physiol Heart Circ Physiol 2011 May 25;300(5):H1583-94. Epub 2011 Feb 25.

Department of Biochemistry and Molecular Biology, Faculty of Medicine, Univ. of Calgary, Calgary, Alberta, Canada.

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http://dx.doi.org/10.1152/ajpheart.01084.2010DOI Listing
May 2011

Competitive uptake and phytomonitoring of chlorinated contaminant mixtures by Redosier dogwood (Cornus sericea).

Int J Phytoremediation 2011 Apr;13(4):333-44

Department of Civil & Environmental Engineering, Southern Illinois University Carbondale, Carbondale, IL 62901, USA.

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http://www.tandfonline.com/doi/abs/10.1080/15226514.2010.495
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http://dx.doi.org/10.1080/15226514.2010.495146DOI Listing
April 2011

Rho-associated kinase plays a role in rabbit urethral smooth muscle contraction, but not via enhanced myosin light chain phosphorylation.

Am J Physiol Renal Physiol 2011 Jan 22;300(1):F73-85. Epub 2010 Sep 22.

Smooth Muscle Research Group and Department of Biochemistry and Molecular Biology, Faculty of Medicine, University of Calgary, Calgary, Alberta, Canada T2N 4N1.

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http://ajprenal.physiology.org/content/ajprenal/300/1/F73.fu
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http://ajprenal.physiology.org/cgi/doi/10.1152/ajprenal.0001
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http://dx.doi.org/10.1152/ajprenal.00011.2010DOI Listing
January 2011

Computational analysis and identification of an emergent human adenovirus pathogen implicated in a respiratory fatality.

Virology 2011 Jan 5;409(2):141-7. Epub 2010 Nov 5.

Howe Laboratory, Massachusetts Eye and Ear Infirmary, Department of Ophthalmology, Harvard Medical School, 243 Charles Street, Boston, MA 02114, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S00426822100066
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http://dx.doi.org/10.1016/j.virol.2010.10.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3006489PMC
January 2011

Wavefront velocity oscillations of carbon-nanotube-guided thermopower waves: nanoscale alternating current sources.

ACS Nano 2011 Jan 23;5(1):367-75. Epub 2010 Dec 23.

Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, United States.

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http://dx.doi.org/10.1021/nn101618yDOI Listing
January 2011

Stromatoxin-sensitive, heteromultimeric Kv2.1/Kv9.3 channels contribute to myogenic control of cerebral arterial diameter.

J Physiol 2010 Nov 27;588(Pt 22):4519-37. Epub 2010 Sep 27.

The Smooth Muscle Research Group, Department of Physiology and Pharmacology, Faculty of Medicine, University of Calgary, 3330 Hospital Drive N.W., Calgary, Alberta, Canada T2N 4N1.

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http://dx.doi.org/10.1113/jphysiol.2010.196618DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3008855PMC
November 2010

Computational analysis of human adenovirus serotype 18.

Virology 2010 Sep 9;404(2):284-92. Epub 2010 Jun 9.

Department of Bioinformatics and Computational Biology, George Mason University, 10900 University Blvd., MSN 5B3, Manassas, VA 20110, USA.

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http://dx.doi.org/10.1016/j.virol.2010.05.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2902685PMC
September 2010

Computational analysis of adenovirus serotype 5 (HAdV-C5) from an HAdV coinfection shows genome stability after 45 years of circulation.

Virology 2010 Sep;404(2):180-6

Department of Bioinformatics and Computational Biology, George Mason University, 10900 University Blvd., MSN 5B3, Manassas, VA 20110, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S004268221000331
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http://dx.doi.org/10.1016/j.virol.2010.05.010DOI Listing
September 2010

Attenuation of store-operated Ca2+ entry and enhanced expression of TRPC channels in caudal artery smooth muscle from Type 2 diabetic Goto-Kakizaki rats.

Clin Exp Pharmacol Physiol 2010 Jul 12;37(7):670-8. Epub 2010 Mar 12.

Department of Pharmacodynamics, Meiji Pharmaceutical University, Tokyo, Japan.

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http://dx.doi.org/10.1111/j.1440-1681.2010.05373.xDOI Listing
July 2010

Pressure-dependent contribution of Rho kinase-mediated calcium sensitization in serotonin-evoked vasoconstriction of rat cerebral arteries.

J Physiol 2010 May 29;588(Pt 10):1747-62. Epub 2010 Mar 29.

The Smooth Muscle Research Group, Department of Physiology and Pharmacology, Faculty of Medicine, University of Calgary, 3330 Hospital Drive N.W., Calgary, Alberta, Canada T2N 4N1.

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http://dx.doi.org/10.1113/jphysiol.2010.187146DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2887992PMC
May 2010

Computational analysis identifies human adenovirus type 55 as a re-emergent acute respiratory disease pathogen.

J Clin Microbiol 2010 Mar 30;48(3):991-3. Epub 2009 Dec 30.

Department of Bioinformatics and Computational Biology, George Mason University, 10900 University Blvd., MSN 5B3, Manassas, Virginia 20110, USA.

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http://jcm.asm.org/content/early/2009/12/30/JCM.01694-09.ful
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http://jcm.asm.org/lookup/doi/10.1128/JCM.01694-09
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http://dx.doi.org/10.1128/JCM.01694-09DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2832463PMC
March 2010

Comparative kinematic evaluation of all-inside single-bundle and double-bundle anterior cruciate ligament reconstruction: a biomechanical study.

Am J Sports Med 2010 Feb 4;38(2):263-72. Epub 2009 Dec 4.

Division of Sports Medicine and the Orthopaedic Biomechanics Laboratory, Department of Orthopaedic Surgery, University of Minnesota, Minneapolis, Minnesota, USA.

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http://dx.doi.org/10.1177/0363546509348053DOI Listing
February 2010

Patellar height and tibial slope after opening-wedge proximal tibial osteotomy: a prospective study.

Am J Sports Med 2010 Jan 18;38(1):160-70. Epub 2009 Sep 18.

Division of Sports Medicine, Department of Orthopaedic Surgery, University of Minnesota, 2450 Riverside Avenue South, R200, Minneapolis, MN 55454, USA.

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http://dx.doi.org/10.1177/0363546509342701DOI Listing
January 2010

Applying genomic and bioinformatic resources to human adenovirus genomes for use in vaccine development and for applications in vector development for gene delivery.

Viruses 2010 Jan 6;2(1):1-26. Epub 2010 Jan 6.

Department of Bioinformatics and Computational Biology, George Mason University, 10900 University Blvd., MSN 5B3, Manassas, VA 20110, USA; E-Mails: (J.S.); (M.P.W.).

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http://www.mdpi.com/1999-4915/2/1/1
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http://dx.doi.org/10.3390/v2010001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3185558PMC
January 2010

Computational analysis of human adenovirus type 22 provides evidence for recombination among species D human adenoviruses in the penton base gene.

J Virol 2009 Sep 24;83(17):8980-5. Epub 2009 Jun 24.

Department of Ophthalmology, Howe Laboratory, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, Massachusetts 02114, USA.

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http://dx.doi.org/10.1128/JVI.00786-09DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2738150PMC
September 2009

The 1:1 versus the 2:2 tunnel-drilling technique: optimization of fixation strength and stiffness in an all-inside double-bundle anterior cruciate ligament reconstruction--a biomechanical study.

Am J Sports Med 2009 Aug 21;37(8):1539-47. Epub 2009 May 21.

Orthopaedic Biomechanics Laboratory, Department of Orthopaedic Surgery, University of Minnesota, Minneapolis, Minnesota, USA.

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August 2009

Ca2+-independent contraction of longitudinal ileal smooth muscle is potentiated by a zipper-interacting protein kinase pseudosubstrate peptide.

Am J Physiol Gastrointest Liver Physiol 2009 Aug 18;297(2):G361-70. Epub 2009 Jun 18.

Smooth Muscle Research Group and Department of Biochemistry and Molecular Biology, University of Calgary, Faculty of Medicine, Calgary, Alberta, Canada.

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http://dx.doi.org/10.1152/ajpgi.00112.2009DOI Listing
August 2009

Genomic and bioinformatics analyses of HAdV-14p, reference strain of a re-emerging respiratory pathogen and analysis of B1/B2.

Virus Res 2009 Jul 2;143(1):94-105. Epub 2009 Apr 2.

Department of Bioinformatics and Computational Biology, George Mason University, 10900 University Blvd., MSN 5B3, Manassas, VA 20110, USA.

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http://dx.doi.org/10.1016/j.virusres.2009.03.011DOI Listing
July 2009

Characterization of tightly associated smooth muscle myosin-myosin light-chain kinase-calmodulin complexes.

J Mol Biol 2009 Jul 25;390(5):879-92. Epub 2009 May 25.

Department of Biochemistry and Molecular Biology, University of Nevada School of Medicine, Reno, 89557, USA.

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http://dx.doi.org/10.1016/j.jmb.2009.05.033DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2742357PMC
July 2009

Ca2+ sensitization via phosphorylation of myosin phosphatase targeting subunit at threonine-855 by Rho kinase contributes to the arterial myogenic response.

J Physiol 2009 Jun 9;587(Pt 11):2537-53. Epub 2009 Apr 9.

Department of Physiology and Pharmacology, Faculty of Medicine, University of Calgary, Calgary, Alberta, Canada.

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http://dx.doi.org/10.1113/jphysiol.2008.168252DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2714019PMC
June 2009

Identification and functional characterization of protein kinase A-catalyzed phosphorylation of potassium channel Kv1.2 at serine 449.

J Biol Chem 2009 Jun 22;284(24):16562-74. Epub 2009 Apr 22.

Smooth Muscle Research Group, Southern Alberta Mass Spectrometry Centre, University of Calgary, Calgary, Alberta, Canada.

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http://dx.doi.org/10.1074/jbc.M109.010918DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2713528PMC
June 2009

Rho-kinase-mediated suppression of KDR current in cerebral arteries requires an intact actin cytoskeleton.

Am J Physiol Heart Circ Physiol 2009 Apr 13;296(4):H917-26. Epub 2009 Feb 13.

Department of Physiology, University of Calgary, Alberta, Canada.

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http://dx.doi.org/10.1152/ajpheart.01206.2008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2670701PMC
April 2009

Myosin light chains are not a physiological substrate of AMPK in the control of cell structure changes.

FEBS Lett 2009 Jan 4;583(1):25-8. Epub 2008 Dec 4.

Université Catholique de Louvain, de Duve Institute, Brussels, Belgium.

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http://dx.doi.org/10.1016/j.febslet.2008.11.022DOI Listing
January 2009

Inhibition of rat aortic smooth muscle contraction by 2-methoxyestradiol.

Am J Physiol Heart Circ Physiol 2008 Nov 5;295(5):H1935-42. Epub 2008 Sep 5.

Smooth Muscle Research Group, Department of Biochemistry and Molecular Biology, University of Calgary, 3330 Hospital Dr. NW, Calgary, Alberta, T2N 4N1 Canada.

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http://www.physiology.org/doi/10.1152/ajpheart.00723.2008
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November 2008

AMP-activated protein kinase phosphorylates and desensitizes smooth muscle myosin light chain kinase.

J Biol Chem 2008 Jul 21;283(27):18505-12. Epub 2008 Apr 21.

Hormone and Metabolic Research Unit, de Duve Institute, Université Catholique de Louvain, B-1200 Brussels.

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http://dx.doi.org/10.1074/jbc.M802053200DOI Listing
July 2008

Ancillary benefits for climate change mitigation and air pollution control in the world's motor vehicle fleets.

Authors:
Michael P Walsh

Annu Rev Public Health 2008 ;29:1-9

International Council on Clean Transportation, Arlington, VA 22207, USA.

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http://dx.doi.org/10.1146/annurev.publhealth.29.091307.083257DOI Listing
June 2008

A highly sensitive technique to measure myosin regulatory light chain phosphorylation: the first quantification in renal arterioles.

Am J Physiol Renal Physiol 2008 Jun 9;294(6):F1487-92. Epub 2008 Apr 9.

Department of Pharmacology, Univ. of Calgary Faculty of Medicine, Smooth Muscle Research Group, 3330 Hospital Dr. N.W., Calgary, Alberta T2N 4N1, Canada.

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http://dx.doi.org/10.1152/ajprenal.00060.2008DOI Listing
June 2008

Up4A stimulates endothelium-independent contraction of isolated rat pulmonary artery.

Am J Physiol Lung Cell Mol Physiol 2008 Apr 11;294(4):L733-8. Epub 2008 Jan 11.

Department of Biochemistry and Molecular Biology, Faculty of Medicine, University of Calgary, Calgary, Alberta, Canada.

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http://www.physiology.org/doi/10.1152/ajplung.00403.2007
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April 2008

The global experience with lead in gasoline and the lessons we should apply to the use of MMT.

Authors:
Michael P Walsh

Am J Ind Med 2007 Nov;50(11):853-60

International Consultant, 3105 North Dinwiddie Street, Arlington, VA 22207, USA.

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http://dx.doi.org/10.1002/ajim.20483DOI Listing
November 2007

Characterization of protein kinase pathways responsible for Ca2+ sensitization in rat ileal longitudinal smooth muscle.

Am J Physiol Gastrointest Liver Physiol 2007 Oct 26;293(4):G699-710. Epub 2007 Jul 26.

Smooth Muscle Research Group and Department of Biochemistry and Molecular Biology, University of Calgary, Faculty of Medicine, Calgary, Alberta, Canada.

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October 2007

Predisposition to tetraploidy in pulmonary vascular smooth muscle cells derived from the Eker rats.

Am J Physiol Lung Cell Mol Physiol 2007 Sep 15;293(3):L702-11. Epub 2007 Jun 15.

Smooth Muscle Research Group, Department of Biochemistry & Molecular Biology, University of Calgary, Calgary, Alberta, Canada.

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http://dx.doi.org/10.1152/ajplung.00016.2007DOI Listing
September 2007

Phosphorylation of the protein phosphatase type 1 inhibitor protein CPI-17 by protein kinase C.

Methods Mol Biol 2007 ;365:209-23

Smooth Muscle Research Group, Department of Biochemistry & Molecular Biology, University of Calgary, Alberta, Canada.

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http://link.springer.com/10.1385/1-59745-267-X:209
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July 2007

The functional consequence of RhoA knockdown by RNA interference in rat cerebral arteries.

Am J Physiol Heart Circ Physiol 2007 Jul 16;293(1):H440-7. Epub 2007 Mar 16.

Department of Physiology and Biophysics, University of Calgary, 3330 Hospital Drive NW, Calgary, Alberta, Canada.

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http://dx.doi.org/10.1152/ajpheart.01374.2006DOI Listing
July 2007

Structures and metal-ion-binding properties of the Ca2+-binding helix-loop-helix EF-hand motifs.

Biochem J 2007 Jul;405(2):199-221

Structural Biology Research Group, Department of Biological Sciences, University of Calgary, Calgary, Alberta, Canada T2N 1N4.

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http://biochemj.org/lookup/doi/10.1042/BJ20070255
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July 2007

Inhibition of zipper-interacting protein kinase function in smooth muscle by a myosin light chain kinase pseudosubstrate peptide.

Am J Physiol Cell Physiol 2007 May 10;292(5):C1951-9. Epub 2007 Jan 10.

Smooth Muscle Research Group and Dept. of Biochemistry and Molecular Biology, University of Calgary, Faculty of Medicine, 3330 Hospital Dr. NW, Calgary, Alberta T2N 4N1, Canada.

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http://dx.doi.org/10.1152/ajpcell.00434.2006DOI Listing
May 2007

Identification of a novel interaction between the Ca(2+)-binding protein S100A11 and the Ca(2+)- and phospholipid-binding protein annexin A6.

Am J Physiol Cell Physiol 2007 Apr 27;292(4):C1417-30. Epub 2006 Dec 27.

Department of Biochemistry and Molecular Biology, University of Calgary Faculty of Medicine, 3330 Hospital Dr. NW, Calgary, Alberta, Canada T2N 4N1.

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http://dx.doi.org/10.1152/ajpcell.00439.2006DOI Listing
April 2007

Endoreduplication of human smooth muscle cells induced by 2-methoxyestradiol: a role for cyclin-dependent kinase 2.

Am J Physiol Heart Circ Physiol 2007 Mar 20;292(3):H1313-20. Epub 2006 Oct 20.

Smooth Muscle Research Group, Department of Biochemistry and Molecular Biology, Faculty of Medicine, Univ of Calgary, Calgary, Alberta, Canada.

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http://www.physiology.org/doi/10.1152/ajpheart.00867.2006
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March 2007

Localization of telokin at the intercalated discs of cardiac myocytes.

Arch Biochem Biophys 2006 Dec 7;456(2):151-60. Epub 2006 Jul 7.

Department of Physiology and Biophysics, University of Calgary, Calgary, Alta., Canada T2N 4N1.

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http://dx.doi.org/10.1016/j.abb.2006.06.018DOI Listing
December 2006

Key role of Kv1 channels in vasoregulation.

Circ Res 2006 Jul 1;99(1):53-60. Epub 2006 Jun 1.

The Smooth Muscle Research Group, Faculty of Medicine, University of Calgary, Alberta, Canada.

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http://dx.doi.org/10.1161/01.RES.0000229654.45090.57DOI Listing
July 2006