Publications by authors named "Michael P Verzi"

50Publications

Control of Cell Identity by the Nuclear Receptor HNF4 in Organ Pathophysiology.

Cells 2020 Sep 28;9(10). Epub 2020 Sep 28.

Institut Pasteur de Lille, The University of Lille, Inserm, CHU Lille, U1011-EGID, F-59000 Lille, France.

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http://dx.doi.org/10.3390/cells9102185DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7600215PMC
September 2020

Epigenetic regulation of intestinal stem cell differentiation.

Am J Physiol Gastrointest Liver Physiol 2020 08 6;319(2):G189-G196. Epub 2020 Jul 6.

Department of Medical Oncology and Center for Functional Cancer Epigenetics, Dana-Farber Cancer Institute, Boston, Massachusetts.

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http://dx.doi.org/10.1152/ajpgi.00084.2020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7500269PMC
August 2020

HNF4 Regulates Fatty Acid Oxidation and Is Required for Renewal of Intestinal Stem Cells in Mice.

Gastroenterology 2020 03 22;158(4):985-999.e9. Epub 2019 Nov 22.

Department of Genetics, Human Genetics Institute of New Jersey, Rutgers University, Piscataway, New Jersey; Rutgers Cancer Institute of New Jersey, New Brunswick, New Jersey; Rutgers Center for Lipid Research, New Brunswick, New Jersey. Electronic address:

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http://dx.doi.org/10.1053/j.gastro.2019.11.031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7062567PMC
March 2020

Vitamin D and the intestine: Review and update.

J Steroid Biochem Mol Biol 2020 02 23;196:105501. Epub 2019 Oct 23.

Department of Nutrition Science, Purdue University, West Lafayette, IN 47907, USA.

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http://dx.doi.org/10.1016/j.jsbmb.2019.105501DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6954280PMC
February 2020

HNF4 factors control chromatin accessibility and are redundantly required for maturation of the fetal intestine.

Development 2019 08 6;146(19). Epub 2019 Aug 6.

Department of Genetics, Human Genetics Institute of New Jersey, Rutgers University, Piscataway, NJ 08854, USA

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http://dx.doi.org/10.1242/dev.179432DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6803367PMC
August 2019

A reinforcing HNF4-SMAD4 feed-forward module stabilizes enterocyte identity.

Nat Genet 2019 05 15;51(5):777-785. Epub 2019 Apr 15.

Department of Genetics, Human Genetics Institute of New Jersey, Rutgers University, Piscataway, NJ, USA.

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http://www.nature.com/articles/s41588-019-0384-0
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http://dx.doi.org/10.1038/s41588-019-0384-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6650150PMC
May 2019

Enhancer, transcriptional, and cell fate plasticity precedes intestinal determination during endoderm development.

Genes Dev 2018 11 26;32(21-22):1430-1442. Epub 2018 Oct 26.

Department of Medical Oncology, Center for Functional Cancer Epigenetics, Dana-Farber Cancer Institute, Boston, Massachusetts 02215, USA.

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http://genesdev.cshlp.org/lookup/doi/10.1101/gad.318832.118
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http://dx.doi.org/10.1101/gad.318832.118DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6217732PMC
November 2018

Paneth Cell Multipotency Induced by Notch Activation following Injury.

Cell Stem Cell 2018 Jul 7;23(1):46-59.e5. Epub 2018 Jun 7.

Department of Biological Sciences, Rutgers University, Newark, NJ 07102, USA; Rutgers Cancer Institute of New Jersey, New Brunswick, NJ 08903, USA. Electronic address:

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http://dx.doi.org/10.1016/j.stem.2018.05.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6035085PMC
July 2018

TFAM is required for maturation of the fetal and adult intestinal epithelium.

Dev Biol 2018 07 22;439(2):92-101. Epub 2018 Apr 22.

Rutgers University, Department of Genetics, Human Genetics Institute of New Jersey (HGINJ), 145 Bevier Road, Piscataway Township, NJ 08854, USA; Rutgers Cancer Institute of New Jersey (CINJ), 195 Little Albany Street, New Brunswick, NJ 08903, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ydbio.2018.04.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5978755PMC
July 2018

Degree of Tissue Differentiation Dictates Susceptibility to BRAF-Driven Colorectal Cancer.

Cell Rep 2017 12;21(13):3833-3845

Department of Genetics, Rutgers University, Human Genetics Institute of New Jersey (HGINJ), 145 Bevier Road, Piscataway Township, NJ 08854, USA; Rutgers Cancer Institute of New Jersey (CINJ), 195 Little Albany Street, New Brunswick, NJ 08903, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S22111247173178
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http://dx.doi.org/10.1016/j.celrep.2017.11.104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5747303PMC
December 2017

Isothiocyanate-enriched moringa seed extract alleviates ulcerative colitis symptoms in mice.

PLoS One 2017 18;12(9):e0184709. Epub 2017 Sep 18.

Department of Plant Biology, Rutgers, The State University of New Jersey, New Brunswick, New Jersey, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0184709PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5602518PMC
October 2017

Mechanisms of colitis-accelerated colon carcinogenesis and its prevention with the combination of aspirin and curcumin: Transcriptomic analysis using RNA-seq.

Biochem Pharmacol 2017 07 4;135:22-34. Epub 2017 Mar 4.

Department of Pharmaceutics, Ernest Mario School of Pharmacy, Rutgers, The State University of New Jersey, Piscataway, NJ 08854, USA. Electronic address:

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http://dx.doi.org/10.1016/j.bcp.2017.02.021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5541256PMC
July 2017

and Function Redundantly During Human Endoderm Differentiation.

Cell Mol Gastroenterol Hepatol 2016 Sep 23;2(5):648-662.e8. Epub 2016 Jun 23.

Division of Gastroenterology, Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, Michigan; Department of Cell and Developmental Biology, University of Michigan Medical School, Ann Arbor, Michigan; Center for Organogenesis, University of Michigan Medical School, Ann Arbor, Michigan.

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http://dx.doi.org/10.1016/j.jcmgh.2016.06.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5042889PMC
September 2016

A YY1-dependent increase in aerobic metabolism is indispensable for intestinal organogenesis.

Development 2016 10;143(20):3711-3722

Rutgers University, Department of Genetics, Human Genetics Institute of New Jersey (HGINJ), 145 Bevier Road, Piscataway Township, NJ 08854, USA

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http://dx.doi.org/10.1242/dev.137992DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5087649PMC
October 2016

Singling Out Intestinal Epithelial Stem Cells.

Gastroenterology 2016 08 29;151(2):228-31. Epub 2016 Jun 29.

Department of Genetics, Human Genetics Institute of New Jersey, and Cancer Institute of New Jersey, Rutgers, the State University of New Jersey, New Brunswick, New Jersey.

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http://dx.doi.org/10.1053/j.gastro.2016.06.031DOI Listing
August 2016

Endothelin signaling activates Mef2c expression in the neural crest through a MEF2C-dependent positive-feedback transcriptional pathway.

Development 2015 Aug 9;142(16):2775-80. Epub 2015 Jul 9.

Cardiovascular Research Institute, University of California, San Francisco, CA 94143, USA Department of Biochemistry and Biophysics, University of California, San Francisco, CA 94143, USA

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http://dev.biologists.org/cgi/doi/10.1242/dev.126391
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http://dx.doi.org/10.1242/dev.126391DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4550968PMC
August 2015

Rab8a vesicles regulate Wnt ligand delivery and Paneth cell maturation at the intestinal stem cell niche.

Development 2015 Jun 26;142(12):2147-62. Epub 2015 May 26.

Department of Biological Sciences, Rutgers University, Newark, NJ 07102, USA Rutgers Cancer Institute of New Jersey, New Brunswick, NJ 08901, USA

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http://dx.doi.org/10.1242/dev.121046DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4483769PMC
June 2015

Transcription factors GATA4 and HNF4A control distinct aspects of intestinal homeostasis in conjunction with transcription factor CDX2.

J Biol Chem 2015 Jan 8;290(3):1850-60. Epub 2014 Dec 8.

From the Department of Medical Oncology and Center for Functional Cancer Epigenetics, Dana-Farber Cancer Institute, Boston, Massachusetts 02215, the Department of Genetics, Rutgers, The State University of New Jersey, Piscataway, New Jersey 08854

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http://dx.doi.org/10.1074/jbc.M114.620211DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4340426PMC
January 2015

CDC42 inhibition suppresses progression of incipient intestinal tumors.

Cancer Res 2014 Oct 11;74(19):5480-92. Epub 2014 Aug 11.

Department of Biological Sciences, Rutgers University, Newark, New Jersey. Rutgers Cancer Institute of New Jersey, New Brunswick, New Jersey.

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http://dx.doi.org/10.1158/0008-5472.CAN-14-0267DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4184946PMC
October 2014

Chromatin profiling reveals regulatory network shifts and a protective role for hepatocyte nuclear factor 4α during colitis.

Mol Cell Biol 2014 Sep 30;34(17):3291-304. Epub 2014 Jun 30.

Human Genetics Institute of New Jersey and Department of Genetics, Rutgers, the State University of New Jersey, Piscataway, New Jersey, USA Rutgers Cancer Institute of New Jersey, New Brunswick, New Jersey, USA

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http://dx.doi.org/10.1128/MCB.00349-14DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4135557PMC
September 2014

YY1 is indispensable for Lgr5+ intestinal stem cell renewal.

Proc Natl Acad Sci U S A 2014 May 12;111(21):7695-700. Epub 2014 May 12.

Department of Genetics, Human Genetics Institute of New Jersey, Cancer Institute of New Jersey, Rutgers, The State University of New Jersey, Piscataway, NJ 08854; and

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http://dx.doi.org/10.1073/pnas.1400128111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4040551PMC
May 2014

Intestinal master transcription factor CDX2 controls chromatin access for partner transcription factor binding.

Mol Cell Biol 2013 Jan 5;33(2):281-92. Epub 2012 Nov 5.

Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1128/MCB.01185-12DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3554120PMC
January 2013

GATA6 is required for proliferation, migration, secretory cell maturation, and gene expression in the mature mouse colon.

Mol Cell Biol 2012 Sep 25;32(17):3392-402. Epub 2012 Jun 25.

Division of Gastroenterology and Nutrition, Department of Medicine, Children's Hospital Boston, and Harvard Medical School, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1128/MCB.00070-12DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3422006PMC
September 2012

Essential and redundant functions of caudal family proteins in activating adult intestinal genes.

Mol Cell Biol 2011 May 14;31(10):2026-39. Epub 2011 Mar 14.

Department of Medical Oncology, Dana-Farber Cancer Institute, 44 Binney Street, Boston, MA 02115, USA.

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http://mcb.asm.org/cgi/doi/10.1128/MCB.01250-10
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http://dx.doi.org/10.1128/MCB.01250-10DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3133364PMC
May 2011

Stem cells: The intestinal-crypt casino.

Nature 2010 Oct;467(7319):1055-6

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http://dx.doi.org/10.1038/4671055aDOI Listing
October 2010

Wnt signaling in gut organogenesis.

Organogenesis 2008 Apr;4(2):87-91

Department of Medical Oncology; Dana-Farber Cancer Institute; and Department of Medicine; Harvard Medical School; Boston, Massachusetts, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2634253PMC
http://dx.doi.org/10.4161/org.4.2.5854DOI Listing
April 2008

Role of the homeodomain transcription factor Bapx1 in mouse distal stomach development.

Gastroenterology 2009 May 14;136(5):1701-10. Epub 2009 Jan 14.

Department of Medical Oncology, Dana-Farber Cancer Institute and Department of Medicine, Harvard Medical School, Boston, Massachusetts 02115, USA.

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http://dx.doi.org/10.1053/j.gastro.2009.01.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2955323PMC
May 2009

Cell-type selective chromatin remodeling defines the active subset of FOXA1-bound enhancers.

Genome Res 2009 Mar 7;19(3):372-80. Epub 2009 Jan 7.

Université de Rennes I, CNRS, UMR 6026, Equipe SPARTE, Campus de Beaulieu, 35042 Rennes cedex, France.

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http://dx.doi.org/10.1101/gr.084582.108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2661808PMC
March 2009

Transcription factor foxq1 controls mucin gene expression and granule content in mouse stomach surface mucous cells.

Gastroenterology 2008 Aug 22;135(2):591-600. Epub 2008 Apr 22.

Dana-Farber Cancer Institute and Department of Medicine, Boston, Massachusetts, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S001650850800671
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http://dx.doi.org/10.1053/j.gastro.2008.04.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2955860PMC
August 2008

The transcription factor MEF2C is required for craniofacial development.

Dev Cell 2007 Apr;12(4):645-52

Cardiovascular Research Institute and Department of Biochemistry and Biophysics, Mail Code 2240, University of California, San Francisco, San Francisco, CA 94143, USA.

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http://dx.doi.org/10.1016/j.devcel.2007.03.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1920108PMC
April 2007

Expression profiles of Na+,K+-ATPase during acute and chronic hypo-osmotic stress in the blue crab Callinectes sapidus.

Biol Bull 2006 Aug;211(1):58-65

Department of Biology, The College of New Jersey, Ewing, New Jersey 08628, USA.

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http://dx.doi.org/10.2307/4134578DOI Listing
August 2006

Pitx2 regulates cardiac left-right asymmetry by patterning second cardiac lineage-derived myocardium.

Dev Biol 2006 Aug 14;296(2):437-49. Epub 2006 Jun 14.

Institute of Biosciences and Technology, Texas A and M System, Health Science Center, 2121 Holcombe Blvd, Houston, TX 77030, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S001216060600910
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http://dx.doi.org/10.1016/j.ydbio.2006.06.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5851592PMC
August 2006

The right ventricle, outflow tract, and ventricular septum comprise a restricted expression domain within the secondary/anterior heart field.

Dev Biol 2005 Nov 26;287(1):134-45. Epub 2005 Sep 26.

Cardiovascular Research Institute, University of California, San Francisco, CA 94143-2240, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S001216060500568
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http://dx.doi.org/10.1016/j.ydbio.2005.08.041DOI Listing
November 2005

Mef2c is a direct transcriptional target of ISL1 and GATA factors in the anterior heart field during mouse embryonic development.

Development 2004 Aug 14;131(16):3931-42. Epub 2004 Jul 14.

Cardiovascular Research Institute, University of California, San Francisco, CA 94143-0130, USA.

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http://dx.doi.org/10.1242/dev.01256DOI Listing
August 2004

N-twist, an evolutionarily conserved bHLH protein expressed in the developing CNS, functions as a transcriptional inhibitor.

Dev Biol 2002 Sep;249(1):174-90

Cardiovascular Research Institute, Univerity of California, San Francisco, California 94143-0130, USA.

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http://dx.doi.org/10.1006/dbio.2002.0753DOI Listing
September 2002