Michael P Snyder

Michael P Snyder

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Michael P Snyder

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HAT1 Coordinates Histone Production and Acetylation via H4 Promoter Binding.

Mol Cell 2019 Aug 2;75(4):711-724.e5. Epub 2019 Jul 2.

Department of Genetics, Stanford School of Medicine, Stanford University, Palo Alto, CA 94304, USA. Electronic address:

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http://dx.doi.org/10.1016/j.molcel.2019.05.034DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6707831PMC
August 2019

Simultaneous RNA purification and size selection using on-chip isotachophoresis with an ionic spacer.

Lab Chip 2019 Aug 22;19(16):2741-2749. Epub 2019 Jul 22.

Department of Genetics, Stanford University School of Medicine, Stanford, CA 94305, USA and Department of Molecular Biosciences, University of Texas at Austin, Austin, TX 78705, USA.

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http://dx.doi.org/10.1039/c9lc00311hDOI Listing
August 2019

Large-Scale Analyses of Human Microbiomes Reveal Thousands of Small, Novel Genes.

Cell 2019 Aug 8;178(5):1245-1259.e14. Epub 2019 Aug 8.

Department of Medicine (Hematology; Blood and Marrow Transplantation) and Genetics, Stanford University, Stanford, CA, USA; Department of Genetics, Stanford University, Stanford, CA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2019.07.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6764417PMC
August 2019

Chromatin Remodeling in Response to BRCA2-Crisis.

Cell Rep 2019 Aug;28(8):2182-2193.e6

Department of Genetics, Stanford University, Stanford, CA 94305, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2019.07.057DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6754178PMC
August 2019

Much ado about nothing: A qualitative study of the experiences of an average-risk population receiving results of exome sequencing.

J Genet Couns 2019 Apr 5;28(2):428-437. Epub 2019 Mar 5.

Department of Genetics, Stanford University School of Medicine, Stanford, California.

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http://dx.doi.org/10.1002/jgc4.1096DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6456364PMC
April 2019

The NASA Twins Study: A multidimensional analysis of a year-long human spaceflight.

Science 2019 04;364(6436)

Northwestern University, Evanston, IL, USA.

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http://dx.doi.org/10.1126/science.aau8650DOI Listing
April 2019

Metformin Affects Heme Function as a Possible Mechanism of Action.

G3 (Bethesda) 2019 02 7;9(2):513-522. Epub 2019 Feb 7.

Department of Genetics, Stanford University, Stanford, CA 94305-5120

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http://g3journal.org/lookup/doi/10.1534/g3.118.200803
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http://dx.doi.org/10.1534/g3.118.200803DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6385989PMC
February 2019

High Throughput Sequencing and Assessing Disease Risk.

Cold Spring Harb Perspect Med 2019 01 2;9(1). Epub 2019 Jan 2.

Department of Genetics, Stanford University, Stanford, California 94305.

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http://dx.doi.org/10.1101/cshperspect.a026849DOI Listing
January 2019

Precision Medicine: Role of Proteomics in Changing Clinical Management and Care.

J Proteome Res 2019 01 22;18(1):1-6. Epub 2018 Oct 22.

Department of Genetics , Stanford University School of Medicine , Stanford , California 94305 , United States.

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http://pubs.acs.org/doi/10.1021/acs.jproteome.8b00504
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http://dx.doi.org/10.1021/acs.jproteome.8b00504DOI Listing
January 2019

Smooth Muscle Contact Drives Endothelial Regeneration by BMPR2-Notch1-Mediated Metabolic and Epigenetic Changes.

Circ Res 2019 01;124(2):211-224

From the Department of Pediatrics (K.M., P.-I.C., J.K.H., C.G.L., T.S., S.T., S.S., A.C., L.W., M.R.), Stanford University School of Medicine, CA.

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http://dx.doi.org/10.1161/CIRCRESAHA.118.313374DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6400637PMC
January 2019

Personalized Metabolomics.

Methods Mol Biol 2019 ;1978:447-456

Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA.

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http://dx.doi.org/10.1007/978-1-4939-9236-2_27DOI Listing
January 2019

Distinct transcriptomic and exomic abnormalities within myelodysplastic syndrome marrow cells.

Leuk Lymphoma 2018 12 4;59(12):2952-2962. Epub 2018 Apr 4.

b Hematology Division , Stanford University School of Medicine, Stanford Cancer Institute , Stanford , CA , USA.

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http://dx.doi.org/10.1080/10428194.2018.1452210DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6214785PMC
December 2018

Integrative omics for health and disease.

Nat Rev Genet 2018 05 26;19(5):299-310. Epub 2018 Feb 26.

Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA.

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http://www.nature.com/doifinder/10.1038/nrg.2018.4
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http://dx.doi.org/10.1038/nrg.2018.4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5990367PMC
May 2018

Personal Omics for Precision Health.

Circ Res 2018 04;122(9):1169-1171

From the Department of Genetics (R.A.K., J.D., M.P.S.)

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http://dx.doi.org/10.1161/CIRCRESAHA.117.310909DOI Listing
April 2018

SETD7 Drives Cardiac Lineage Commitment through Stage-Specific Transcriptional Activation.

Cell Stem Cell 2018 03;22(3):428-444.e5

Stanford Cardiovascular Institute, Stanford University School of Medicine, Stanford, CA 94305, USA; Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA; Department of Medicine, Division of Cardiology, Stanford University School of Medicine, Stanford, CA 94305, USA. Electronic address:

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http://dx.doi.org/10.1016/j.stem.2018.02.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5929163PMC
March 2018

mutation associated with pseudorheumatoid dysplasia.

Cold Spring Harb Mol Case Stud 2018 02 1;4(1). Epub 2018 Feb 1.

Department of Genetics, Stanford University, Stanford, California 94304, USA.

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http://dx.doi.org/10.1101/mcs.a001990DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5793776PMC
February 2018

Cell Type-Specific Chromatin Signatures Underline Regulatory DNA Elements in Human Induced Pluripotent Stem Cells and Somatic Cells.

Circ Res 2017 Nov 13;121(11):1237-1250. Epub 2017 Oct 13.

From the Stanford Cardiovascular Institute, Department of Medicine, Division of Cardiology, Institute of Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, CA (M.-T.Z., N.-Y.S., N.M., J.L., S.L.Z., J.C.W.); Department of Cardiovascular Surgery of the Frist Affiliated Hospital, Institute for Cardiovascular Science, Soochow University, Suzhou, Jiangsu, China (S.H.); Department of Chemical and Systems Biology, Stanford University School of Medicine, CA (R.S.); and Department of Genetics, Stanford University School of Medicine, CA (F.J., M.P.S.).

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http://dx.doi.org/10.1161/CIRCRESAHA.117.311367DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5773062PMC
November 2017

Plasma sterols and depressive symptom severity in a population-based cohort.

PLoS One 2017 8;12(9):e0184382. Epub 2017 Sep 8.

Department of Psychiatry, The University of Texas Southwestern Medical Center, Dallas, Texas, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0184382PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5590924PMC
October 2017

Topological organization and dynamic regulation of human tRNA genes during macrophage differentiation.

Genome Biol 2017 09 20;18(1):180. Epub 2017 Sep 20.

Department of Genetics, Stanford University, Stanford, CA, 94305, USA.

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http://dx.doi.org/10.1186/s13059-017-1310-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5607496PMC
September 2017

Genome-Wide Temporal Profiling of Transcriptome and Open Chromatin of Early Cardiomyocyte Differentiation Derived From hiPSCs and hESCs.

Circ Res 2017 Aug 29;121(4):376-391. Epub 2017 Jun 29.

From the Department of Genetics (Q.L., C.J., K.V.B., M.P.S.), Center for Personal Dynamic Regulomes (J.X., H.Y.C.), Stanford Cardiovascular Institute (M.T.Z., J.C.W.), and Stem Cell Core Facility, Department of Genetics (X.C., G.W.), Stanford University School of Medicine, CA.

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http://dx.doi.org/10.1161/CIRCRESAHA.116.310456DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5576565PMC
August 2017

A Case Report of Hypoglycemia and Hypogammaglobulinemia: DAVID Syndrome in a Patient With a Novel NFKB2 Mutation.

J Clin Endocrinol Metab 2017 07;102(7):2127-2130

Division of Allergy, Immunology & Rheumatology, Department of Pediatrics, Stanford University School of Medicine, Stanford, California 94305.

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http://dx.doi.org/10.1210/jc.2017-00341DOI Listing
July 2017

Patient-Specific iPSC-Derived Endothelial Cells Uncover Pathways that Protect against Pulmonary Hypertension in BMPR2 Mutation Carriers.

Cell Stem Cell 2017 04 22;20(4):490-504.e5. Epub 2016 Dec 22.

Vera Moulton Wall Center for Pulmonary Vascular Diseases, Stanford University School of Medicine, Stanford, CA 94305, USA; Stanford Cardiovascular Institute, Stanford University School of Medicine, Stanford, CA 94305, USA; Department of Pediatrics, Stanford University School of Medicine, Stanford, CA 94305, USA. Electronic address:

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http://www.cell.com/cell-stem-cell/pdf/S1934-5909(16)30266-1
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http://linkinghub.elsevier.com/retrieve/pii/S193459091630266
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http://dx.doi.org/10.1016/j.stem.2016.08.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5500296PMC
April 2017

A common class of transcripts with 5'-intron depletion, distinct early coding sequence features, and -methyladenosine modification.

RNA 2017 03 19;23(3):270-283. Epub 2016 Dec 19.

Donnelly Centre, Department of Molecular Genetics, and Department of Computer Science, University of Toronto, Toronto M5S 3E1, Ontario, Canada

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http://dx.doi.org/10.1261/rna.059105.116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5311483PMC
March 2017

ChIA-PET2: a versatile and flexible pipeline for ChIA-PET data analysis.

Nucleic Acids Res 2017 01 12;45(1):e4. Epub 2016 Sep 12.

MOE Key Laboratory of Bioinformatics; Bioinformatics Division and Center for Synthetic & Systems Biology, TNLIST; Department of Automation, Tsinghua University, Beijing 100084, China

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http://dx.doi.org/10.1093/nar/gkw809DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5224499PMC
January 2017

Disease Model of GATA4 Mutation Reveals Transcription Factor Cooperativity in Human Cardiogenesis.

Cell 2016 Dec;167(7):1734-1749.e22

Gladstone Institute of Cardiovascular Disease and Roddenberry Center for Stem Cell Biology and Medicine, San Francisco, CA 94158, USA; Department of Pediatrics, University of California, San Francisco, San Francisco, CA 94143, USA; Department of Biochemistry and Biophysics, University of California, San Francisco, San Francisco, CA 94143, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2016.11.033DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5180611PMC
December 2016

Can heavy isotopes increase lifespan? Studies of relative abundance in various organisms reveal chemical perspectives on aging.

Bioessays 2016 11 24;38(11):1093-1101. Epub 2016 Aug 24.

Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA.

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http://dx.doi.org/10.1002/bies.201600040DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5108472PMC
November 2016

Simul-seq: combined DNA and RNA sequencing for whole-genome and transcriptome profiling.

Nat Methods 2016 Nov 10;13(11):953-958. Epub 2016 Oct 10.

Department of Genetics, Stanford University School of Medicine, Stanford, California, USA.

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http://dx.doi.org/10.1038/nmeth.4028DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5734913PMC
November 2016

Transcriptome Profiling of Patient-Specific Human iPSC-Cardiomyocytes Predicts Individual Drug Safety and Efficacy Responses In Vitro.

Cell Stem Cell 2016 09 18;19(3):311-25. Epub 2016 Aug 18.

Stanford Cardiovascular Institute, Stanford University School of Medicine, Stanford, CA 94305, USA; Departments of Medicine and Radiology, Stanford University School of Medicine, Stanford, CA 94305, USA; Institute of Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA. Electronic address:

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5087997PMC
http://dx.doi.org/10.1016/j.stem.2016.07.006DOI Listing
September 2016

Metformin Improves Diabetic Bone Health by Re-Balancing Catabolism and Nitrogen Disposal.

PLoS One 2015 30;10(12):e0146152. Epub 2015 Dec 30.

Basic Science and Craniofacial Biology, New York University College of Dentistry, New York, NY 10010, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0146152PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4696809PMC
July 2016

Genome assembly from synthetic long read clouds.

Bioinformatics 2016 06;32(12):i216-i224

Department of Computer Science, Stanford University.

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http://dx.doi.org/10.1093/bioinformatics/btw267DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4908351PMC
June 2016

Protein substrates of the arginine methyltransferase Hmt1 identified by proteome arrays.

Proteomics 2016 Feb;16(3):465-76

Systems Biology Initiative, School of Biotechnology and Biomolecular Sciences, The University of New South Wales, Sydney, Australia.

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http://dx.doi.org/10.1002/pmic.201400564DOI Listing
February 2016

Identification of significantly mutated regions across cancer types highlights a rich landscape of functional molecular alterations.

Nat Genet 2016 Feb 21;48(2):117-25. Epub 2015 Dec 21.

Department of Genetics, Stanford University School of Medicine, Stanford, California, USA.

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http://dx.doi.org/10.1038/ng.3471DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4731297PMC
February 2016

Yeast longevity promoted by reversing aging-associated decline in heavy isotope content.

NPJ Aging Mech Dis 2016 18;2:16004. Epub 2016 Feb 18.

Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA.

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http://dx.doi.org/10.1038/npjamd.2016.4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5515009PMC
February 2016

Systematic evaluation of the impact of ChIP-seq read designs on genome coverage, peak identification, and allele-specific binding detection.

BMC Bioinformatics 2016 Feb 24;17:96. Epub 2016 Feb 24.

Department of Statistics, University of Wisconsin Madison, Madison, Wisconsin, USA.

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http://dx.doi.org/10.1186/s12859-016-0957-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4765064PMC
February 2016

NIH working group report-using genomic information to guide weight management: From universal to precision treatment.

Obesity (Silver Spring) 2016 Jan;24(1):14-22

Division of Cancer Control and Population Sciences, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA.

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http://dx.doi.org/10.1002/oby.21381DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4689320PMC
January 2016

Integrated Proteomic and Genomic Analysis of Gastric Cancer Patient Tissues.

J Proteome Res 2015 Dec 20;14(12):4995-5006. Epub 2015 Oct 20.

Barnett Institute and Department of Chemistry and Chemical Biology, Northeastern University , 360 Huntington Avenue, Boston, Massachusetts 02115, United States.

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http://dx.doi.org/10.1021/acs.jproteome.5b00827DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5706558PMC
December 2015

Mango: a bias-correcting ChIA-PET analysis pipeline.

Bioinformatics 2015 Oct 1;31(19):3092-8. Epub 2015 Jun 1.

Department of Genetics, Stanford University School of Medicine, Stanford, CA 94305 and.

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http://dx.doi.org/10.1093/bioinformatics/btv336DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4592333PMC
October 2015

Evaluating Common Humoral Responses against Fungal Infections with Yeast Protein Microarrays.

J Proteome Res 2015 Sep 21;14(9):3924-31. Epub 2015 Aug 21.

Division of Infectious Diseases and Geographic Medicine, Stanford University , 300 Pasteur Drive, Lane L-134, Stanford, California 94305-5107, United States.

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http://dx.doi.org/10.1021/acs.jproteome.5b00365DOI Listing
September 2015

Probing High-density Functional Protein Microarrays to Detect Protein-protein Interactions.

J Vis Exp 2015 Aug 2(102):e51872. Epub 2015 Aug 2.

Department of Genetics, Stanford University; Stanford Center for Genomics and Personalized Medicine, Stanford University;

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http://dx.doi.org/10.3791/51872DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4545172PMC
August 2015

Single-cell chromatin accessibility reveals principles of regulatory variation.

Nature 2015 Jul 17;523(7561):486-90. Epub 2015 Jun 17.

1] Department of Genetics, Stanford University School of Medicine, Stanford, California 94305, USA [2] Department of Applied Physics, Stanford University, Stanford, California 94025, USA.

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http://dx.doi.org/10.1038/nature14590DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4685948PMC
July 2015

Transcriptome Signature and Regulation in Human Somatic Cell Reprogramming.

Stem Cell Reports 2015 Jun 21;4(6):1125-39. Epub 2015 May 21.

Department of Genetics, Yale Stem Cell Center, Yale School of Medicine, New Haven, CT 06520, USA. Electronic address:

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http://dx.doi.org/10.1016/j.stemcr.2015.04.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4471828PMC
June 2015

High-throughput sequencing technologies.

Mol Cell 2015 May;58(4):586-97

Department of Genetics, Stanford University School of Medicine, Stanford, CA 94305, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S10972765150034
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http://dx.doi.org/10.1016/j.molcel.2015.05.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4494749PMC
May 2015

Personalized sequencing and the future of medicine: discovery, diagnosis and defeat of disease.

Pharmacogenomics 2014 Nov;15(14):1771-1790

300 Pasteur Drive, Department of Genetics, Stanford University School of Medicine, Stanford, CA 94305, USA.

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http://dx.doi.org/10.2217/pgs.14.117DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4336568PMC
November 2014