Michael Overman

Michael Overman

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Michael Overman

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Sarcomatoid carcinoma presenting as cancers of unknown primary: a clinicopathological portrait.

BMC Cancer 2019 Oct 17;19(1):965. Epub 2019 Oct 17.

Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX, 77030, USA.

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http://dx.doi.org/10.1186/s12885-019-6155-6DOI Listing
October 2019

Mismatch Repair-Proficient Colorectal Cancer: Finding the Right TiME to Respond.

Clin Cancer Res 2019 Sep 1;25(17):5185-5187. Epub 2019 Jul 1.

Department of GI Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.

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http://dx.doi.org/10.1158/1078-0432.CCR-19-1447DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6726523PMC
September 2019

Small Bowel Adenocarcinoma: Etiology, Presentation, and Molecular Alterations.

J Natl Compr Canc Netw 2019 Sep;17(9):1135-1141

bDepartment of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.

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http://dx.doi.org/10.6004/jnccn.2019.7344DOI Listing
September 2019

Retrospective Analysis of Taxane-Based Therapy in Small Bowel Adenocarcinoma.

Oncologist 2019 Jun 31;24(6):e384-e386. Epub 2018 Dec 31.

Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA

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http://dx.doi.org/10.1634/theoncologist.2018-0573DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6656507PMC
June 2019

Immunotherapy in colorectal cancer with mismatch repair deficiency.

Clin Adv Hematol Oncol 2019 May;17(5):265-267

The University of Texas MD Anderson Cancer Center, Houston, Texas.

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May 2019

Predictors of Survival in Patients with Advanced Gastrointestinal Malignancies Admitted to the Intensive Care Unit.

Oncologist 2019 Apr 5;24(4):483-490. Epub 2018 Dec 5.

Department of Gastrointestinal Medical Oncology, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA

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http://dx.doi.org/10.1634/theoncologist.2018-0328DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6459253PMC
April 2019

Assessment of Reported Trial Characteristics, Rate of Publication, and Inclusion of Mandatory Biopsies of Research Biopsies in Clinical Trials in Oncology.

JAMA Oncol 2019 Mar;5(3):402-405

Division of Cancer Medicine, Department of Gastrointestinal Medical Oncology, The University of Texas M.D. Anderson Cancer Center, Houston.

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http://dx.doi.org/10.1001/jamaoncol.2018.4640DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6439840PMC
March 2019

Back to the Colorectal Cancer Consensus Molecular Subtype Future.

Curr Gastroenterol Rep 2019 Jan 30;21(2). Epub 2019 Jan 30.

Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard--Unit 0426, Houston, TX, 77030, USA.

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http://dx.doi.org/10.1007/s11894-019-0674-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6622456PMC
January 2019

Integrating Biomarkers and Targeted Therapy Into Colorectal Cancer Management.

Am Soc Clin Oncol Educ Book 2019 Jan 17;39:207-215. Epub 2019 May 17.

3 Department of Gastrointestinal Medical Oncology, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX.

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http://dx.doi.org/10.1200/EDBK_240839DOI Listing
January 2019

Discrepancies in endpoints between clinical trial protocols and clinical trial registration in randomized trials in oncology.

BMC Med Res Methodol 2018 12 12;18(1):169. Epub 2018 Dec 12.

Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson, 1515 Holcombe Blvd, Unit 426, Houston, TX, 77030, USA.

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https://bmcmedresmethodol.biomedcentral.com/articles/10.1186
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http://dx.doi.org/10.1186/s12874-018-0627-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6292048PMC
December 2018

Bevacizumab as a chemoprotectant: reducing oxaliplatin induced hepatic sinusoidal injury.

Oncotarget 2018 Oct 9;9(79):34857-34858. Epub 2018 Oct 9.

Michael J. Overman: Department of Gastrointestinal Medical Oncology, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.

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http://dx.doi.org/10.18632/oncotarget.26207DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6201853PMC
October 2018

Bioactive lipid metabolism in platelet "first responder" and cancer biology.

Cancer Metastasis Rev 2018 09;37(2-3):439-454

Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, 77054, USA.

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http://dx.doi.org/10.1007/s10555-018-9755-8DOI Listing
September 2018

Facile profiling of molecular heterogeneity by microfluidic digital melt.

Sci Adv 2018 09 28;4(9):eaat6459. Epub 2018 Sep 28.

Department of Biomedical Engineering, Johns Hopkins School of Medicine, Baltimore, MD 21218, USA.

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http://dx.doi.org/10.1126/sciadv.aat6459DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6157960PMC
September 2018

The Addition of Bevacizumab to Oxaliplatin-Based Chemotherapy: Impact Upon Hepatic Sinusoidal Injury and Thrombocytopenia.

J Natl Cancer Inst 2018 08;110(8):888-894

Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX.

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http://dx.doi.org/10.1093/jnci/djx288DOI Listing
August 2018

Nivolumab in the treatment of microsatellite instability high metastatic colorectal cancer.

Future Oncol 2018 08 23;14(18):1869-1874. Epub 2018 Feb 23.

Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, 1400 Holcombe Blvd, Houston, TX 77030, USA.

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http://dx.doi.org/10.2217/fon-2017-0696DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6088272PMC
August 2018

Ethics and the Underreporting of Research Biopsy Findings in Clinical Trials.

JAMA Oncol 2018 08;4(8):1041-1042

Department of Medical Ethics and Health Policy, University of Pennsylvania Perelman School of Medicine, Division of Oncology, Children's Hospital of Philadelphia, Philadelphia.

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http://dx.doi.org/10.1001/jamaoncol.2018.1002DOI Listing
August 2018

Randomized, phase I/II study of gemcitabine plus IGF-1R antagonist (MK-0646) versus gemcitabine plus erlotinib with and without MK-0646 for advanced pancreatic adenocarcinoma.

J Hematol Oncol 2018 05 30;11(1):71. Epub 2018 May 30.

Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd, Unit 426, Houston, TX, 77030, USA.

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http://dx.doi.org/10.1186/s13045-018-0616-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5975422PMC
May 2018

Where We Stand With Immunotherapy in Colorectal Cancer: Deficient Mismatch Repair, Proficient Mismatch Repair, and Toxicity Management.

Am Soc Clin Oncol Educ Book 2018 May;38:239-247

From the Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX; Roswell Park Cancer Center, Buffalo, NY, Division of Hematology Oncology, Department of Medicine, University of Buffalo, Buffalo, NY; Department of Medicine, Duke University Medical Center, Durham, NC.

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http://ascopubs.org/doi/10.1200/EDBK_200821
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http://dx.doi.org/10.1200/EDBK_200821DOI Listing
May 2018

Platelet Metabolism and Other Targeted Drugs; Potential Impact on Immunotherapy.

Front Oncol 2018 20;8:107. Epub 2018 Apr 20.

Department of GI Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, United States.

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http://dx.doi.org/10.3389/fonc.2018.00107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5919962PMC
April 2018

Durable Clinical Benefit With Nivolumab Plus Ipilimumab in DNA Mismatch Repair-Deficient/Microsatellite Instability-High Metastatic Colorectal Cancer.

J Clin Oncol 2018 03 20;36(8):773-779. Epub 2018 Jan 20.

Michael J. Overman and Scott Kopetz, University of Texas MD Anderson Cancer Center, Houston, TX; Sara Lonardi, Istituto Oncologico Veneto, Istituto di Ricovero e Cura a Carattere Scientifico, Padova; Fabio Gelsomino, University Hospital of Modena, Modena; Massimo Aglietta, Institute for Cancer Research and Treatment of Candiolo, University of Torino Medical School, Turin, Italy; Ka Yeung Mark Wong, Sydney Medical School, University of Sydney, Sydney, New South Wales; Andrew Hill, Tasman Oncology Research, Ltd., Southport, Queensland, Australia; Heinz-Josef Lenz, University of Southern California Norris Comprehensive Cancer Center, Los Angeles, CA; Michael A. Morse, Duke University Medical Center, Durham, NC; Eric Van Cutsem, University Hospitals Gasthuisberg Leuven and Katholieke Universiteit Leuven, Leuven; Alain Hendlisz, Institut Jules Bordet; Bart Neyns, Universitair Ziekenhuis Brussel, Brussels; Jean-Marie Ledeine, Bristol-Myers Squibb, Braine-L'Alleud, Belgium; Ray McDermott, St Vincent's University Hospital and Cancer Trials Ireland, Dublin, Ireland; Michael B. Sawyer, Cross Cancer Institute and University of Alberta, Edmonton, Alberta, Canada; Magali Svrcek and Thierry André, Hopital Saint Antoine, Assistance Publique Hôpitaux de Paris and Sorbonne Universités, Université Pierre et Marie Curie, Paris, France; and Rebecca A. Moss, Z. Alexander Cao, and Shital Kamble, Bristol-Myers Squibb, Princeton, NJ.

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http://ascopubs.org/doi/10.1200/JCO.2017.76.9901
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http://dx.doi.org/10.1200/JCO.2017.76.9901DOI Listing
March 2018

Long-Term Remissions of Patients With Follicular Lymphoma Grade 3 Treated With R-CHOP.

Clin Lymphoma Myeloma Leuk 2018 01 14;18(1):e103-e108. Epub 2017 Nov 14.

Department of Lymphoma and Myeloma, The University of Texas, M.D. Anderson Cancer Center, Houston, TX. Electronic address:

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http://dx.doi.org/10.1016/j.clml.2017.11.001DOI Listing
January 2018

Genomic Profiling of Small-Bowel Adenocarcinoma.

JAMA Oncol 2017 Nov;3(11):1546-1553

Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston.

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http://dx.doi.org/10.1001/jamaoncol.2017.1051DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5710195PMC
November 2017

Underreporting of Research Biopsies from Clinical Trials in Oncology.

Clin Cancer Res 2017 Nov 28;23(21):6450-6457. Epub 2017 Jul 28.

Department of Gastrointestinal Medical Oncology, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas.

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http://dx.doi.org/10.1158/1078-0432.CCR-17-1449DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5668146PMC
November 2017

Can we navigate chemotherapy-induced hepatic injuries from pathology to bedside?

J Hepatol 2017 07 3;67(1):10-11. Epub 2017 May 3.

Department of Hepato-Pancreato-Biliary Surgery and Transplantation, Hôpital Beaujon, Université Paris VII, Clichy Cedex, France. Electronic address:

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http://dx.doi.org/10.1016/j.jhep.2017.04.011DOI Listing
July 2017

Retrospective study of nonmucinous appendiceal adenocarcinomas: role of systemic chemotherapy and cytoreductive surgery.

BMC Cancer 2017 05 15;17(1):331. Epub 2017 May 15.

Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd., Unit 0426, Houston, TX, 77030, USA.

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http://bmccancer.biomedcentral.com/articles/10.1186/s12885-0
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http://dx.doi.org/10.1186/s12885-017-3327-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5433007PMC
May 2017

Is hepatectomy justified for patients with RAS mutant colorectal liver metastases? An analysis of 524 patients undergoing curative liver resection.

Surgery 2017 02 31;161(2):332-340. Epub 2016 Aug 31.

Department of Surgical Oncology, The University of Texas M.D. Anderson Cancer Center, Houston, TX. Electronic address:

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http://dx.doi.org/10.1016/j.surg.2016.07.032DOI Listing
February 2017

Immunotherapy Progress in Mismatch Repair-Deficient Colorectal Cancer and Future Therapeutic Challenges.

Cancer J 2016 May-Jun;22(3):190-5

From the Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX.

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http://dx.doi.org/10.1097/PPO.0000000000000196DOI Listing
January 2017

Low-grade Appendiceal Mucinous Neoplasm of Uncertain Malignant Potential (LAMN-UMP): Prognostic Factors and Implications for Treatment and Follow-up.

Ann Surg Oncol 2017 Jan 22;24(1):187-193. Epub 2016 Sep 22.

Department of Surgical Oncology, University of Texas MD Anderson Cancer Center, Houston, TX, USA.

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http://dx.doi.org/10.1245/s10434-016-5588-2DOI Listing
January 2017

Intrathoracic Chemoperfusion Decreases Recurrences in Patients with Full-Thickness Diaphragm Involvement with Mucinous Appendiceal Adenocarcinoma.

Ann Surg Oncol 2016 09 30;23(9):2914-9. Epub 2016 Mar 30.

Department of Surgical Oncology, University of Texas MD Anderson Cancer Center, Houston, TX, USA.

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http://dx.doi.org/10.1245/s10434-016-5209-0DOI Listing
September 2016

Performance and prognostic utility of the 92-gene assay in the molecular subclassification of ampullary adenocarcinoma.

BMC Cancer 2016 08 22;16:668. Epub 2016 Aug 22.

Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, Unit 426, 1515 Holcombe Blvd, Unit 421, Houston, TX, 77030, USA.

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http://dx.doi.org/10.1186/s12885-016-2677-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4994309PMC
August 2016

High-Grade Neuroendocrine Colorectal Carcinomas: A Retrospective Study of 100 Patients.

Clin Colorectal Cancer 2016 Jun 29;15(2):e1-7. Epub 2015 Dec 29.

Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX. Electronic address:

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http://dx.doi.org/10.1016/j.clcc.2015.12.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4885752PMC
June 2016

Association of CpG island methylator phenotype and EREG/AREG methylation and expression in colorectal cancer.

Br J Cancer 2016 06 7;114(12):1352-61. Epub 2016 Jun 7.

Department of Gastrointestinal Medical Oncology, University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA.

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http://dx.doi.org/10.1038/bjc.2016.87DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4984478PMC
June 2016

Acute benzodiazepine toxicity exacerbated by concomitant oral olanzapine.

J Community Support Oncol 2016 Apr;14(4):178-9

Department of Critical Care, MD Anderson Cancer Center, Houston, Texas, USA.

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http://dx.doi.org/10.12788/jcso.0187DOI Listing
April 2016

Retrospective analysis of systemic chemotherapy and total parenteral nutrition for the treatment of malignant small bowel obstruction.

Cancer Med 2016 Feb 29;5(2):239-47. Epub 2015 Dec 29.

Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.

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http://doi.wiley.com/10.1002/cam4.587
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http://dx.doi.org/10.1002/cam4.587DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4735773PMC
February 2016

ABO non-O type as a risk factor for thrombosis in patients with pancreatic cancer.

Cancer Med 2015 Nov 15;4(11):1651-8. Epub 2015 Aug 15.

Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.

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http://dx.doi.org/10.1002/cam4.513DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4673991PMC
November 2015

From Protocols to Publications: A Study in Selective Reporting of Outcomes in Randomized Trials in Oncology.

J Clin Oncol 2015 Nov 24;33(31):3583-90. Epub 2015 Aug 24.

Kanwal Pratap Singh Raghav, Sminil Mahajan, James C. Yao, Brian P. Hobbs, Donald A. Berry, Alda Tam, Waun K. Hong, Lee M. Ellis, and Michael J. Overman, The University of Texas MD Anderson Cancer Center, Houston, TX; Rebecca D. Pentz, Emory School of Medicine, Atlanta, GA; and James Abbruzzese, Duke Cancer Institute, Durham, NC.

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http://dx.doi.org/10.1200/JCO.2015.62.4148DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4979242PMC
November 2015

A Prospective Six Sigma Quality Improvement Trial to Optimize Universal Screening for Genetic Syndrome Among Patients With Young-Onset Colorectal Cancer.

J Natl Compr Canc Netw 2015 Jul;13(7):865-72

From the Departments of Surgical Oncology, Gastroenterology and Hepatology, Pathology, Quality Improvement, and Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.

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http://dx.doi.org/10.6004/jnccn.2015.0103DOI Listing
July 2015

Goblet cell carcinoid tumor, mixed goblet cell carcinoid-adenocarcinoma, and adenocarcinoma of the appendix: comparison of clinicopathologic features and prognosis.

Arch Pathol Lab Med 2015 Jun;139(6):782-90

From the Departments of Pathology (Drs Taggart, Abraham, and Rashid), Medical Oncology (Dr Overman), and Surgical Oncology (Dr Mansfield), MD Anderson Cancer Center, University of Texas, Houston.

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http://dx.doi.org/10.5858/arpa.2013-0047-OADOI Listing
June 2015

A phase II, randomized, double blind trial of calcium aluminosilicate clay versus placebo for the prevention of diarrhea in patients with metastatic colorectal cancer treated with irinotecan.

Support Care Cancer 2015 Mar 27;23(3):661-70. Epub 2014 Aug 27.

Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd., Unit 0426, Houston, TX, 77030, USA,

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http://dx.doi.org/10.1007/s00520-014-2402-1DOI Listing
March 2015

Challenges of efficacy assessments in pseudomyxoma peritonea.

Oncologist 2015 Mar;20(3):e3-4

Department of Surgical Oncology, University of Texas MD Anderson Cancer Center, Houston, Texas, USA.

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http://dx.doi.org/10.1634/theoncologist.2014-0415DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4350806PMC
March 2015

Epithelial-mesenchymal transitioned circulating tumor cells capture for detecting tumor progression.

Clin Cancer Res 2015 Feb 16;21(4):899-906. Epub 2014 Dec 16.

Department of Pediatrics, The University of Texas MD Anderson Cancer Center, Houston, Texas. The University of Texas Graduate School of Biomedical Sciences, Houston, Texas.

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http://dx.doi.org/10.1158/1078-0432.CCR-14-0894DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4334736PMC
February 2015

Progression-free survival remains poor over sequential lines of systemic therapy in patients with BRAF-mutated colorectal cancer.

Clin Colorectal Cancer 2014 Sep 23;13(3):164-71. Epub 2014 Jun 23.

Department of Gastrointestinal Medical Oncology, The University of Texas M.D. Anderson Cancer Center, Houston, TX. Electronic address:

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http://dx.doi.org/10.1016/j.clcc.2014.06.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4266576PMC
September 2014

Src activity is modulated by oxaliplatin and correlates with outcomes after hepatectomy for metastatic colorectal cancer.

BMC Cancer 2014 Sep 10;14:660. Epub 2014 Sep 10.

Department of Genitourinary Medical Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Unit 0018-4, Houston, TX 77030, USA.

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http://dx.doi.org/10.1186/1471-2407-14-660DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4167273PMC
September 2014

Aberrant expression of p53, p21, cyclin D1, and Bcl2 and their clinicopathological correlation in ampullary adenocarcinoma.

Hum Pathol 2014 May 17;45(5):1015-23. Epub 2014 Jan 17.

Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030. Electronic address:

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http://dx.doi.org/10.1016/j.humpath.2013.12.016DOI Listing
May 2014

The expression of PTEN is associated with improved prognosis in patients with ampullary adenocarcinoma after pancreaticoduodenectomy.

Arch Pathol Lab Med 2013 Nov;137(11):1619-26

From the Departments of Pathology (Drs S. Shroff, Rashid, and Huamin Wang), Gastrointestinal Medical Oncology (Drs Overman, R. T. Shroff, Hua Wang, Wolff, and Abbruzzese), and Surgical Oncology (Drs Chatterjee, Katz, Lee, and Fleming). The University of Texas M. D. Anderson Cancer Center, Houston.

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http://dx.doi.org/10.5858/arpa.2012-0418-OADOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4640926PMC
November 2013