Michael N Routledge

Michael N Routledge

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Michael N Routledge

Michael N Routledge

Publications by authors named "Michael N Routledge"

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In vitro effects of single and binary mixtures of regulated mycotoxins and persistent organochloride pesticides on steroid hormone production in MA-10 Leydig cell line.

Toxicol In Vitro 2019 Oct 11;60:272-280. Epub 2019 Jun 11.

School of Food Science and Nutrition, Food Science Building, University of Leeds, LS2 9JT, UK; Department of Food Safety Risk Assessment, China National Center for Food Safety Risk Assessment, Ministry of Health, Beijing, 100021, China.

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http://dx.doi.org/10.1016/j.tiv.2019.06.007DOI Listing
October 2019

The effect of individual and mixtures of mycotoxins and persistent organochloride pesticides on oestrogen receptor transcriptional activation using in vitro reporter gene assays.

Food Chem Toxicol 2019 Aug 10;130:68-78. Epub 2019 May 10.

Institute for Global Food Security, School of Biological Sciences, Queens University Belfast, Northern Ireland, BT9 5AF, UK.

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http://dx.doi.org/10.1016/j.fct.2019.05.014DOI Listing
August 2019

Meta-analysis of epigenome-wide association studies in neonates reveals widespread differential DNA methylation associated with birthweight.

Authors:
Leanne K Küpers Claire Monnereau Gemma C Sharp Paul Yousefi Lucas A Salas Akram Ghantous Christian M Page Sarah E Reese Allen J Wilcox Darina Czamara Anne P Starling Alexei Novoloaca Samantha Lent Ritu Roy Cathrine Hoyo Carrie V Breton Catherine Allard Allan C Just Kelly M Bakulski John W Holloway Todd M Everson Cheng-Jian Xu Rae-Chi Huang Diana A van der Plaat Matthias Wielscher Simon Kebede Merid Vilhelmina Ullemar Faisal I Rezwan Jari Lahti Jenny van Dongen Sabine A S Langie Tom G Richardson Maria C Magnus Ellen A Nohr Zongli Xu Liesbeth Duijts Shanshan Zhao Weiming Zhang Michelle Plusquin Dawn L DeMeo Olivia Solomon Joosje H Heimovaara Dereje D Jima Lu Gao Mariona Bustamante Patrice Perron Robert O Wright Irva Hertz-Picciotto Hongmei Zhang Margaret R Karagas Ulrike Gehring Carmen J Marsit Lawrence J Beilin Judith M Vonk Marjo-Riitta Jarvelin Anna Bergström Anne K Örtqvist Susan Ewart Pia M Villa Sophie E Moore Gonneke Willemsen Arnout R L Standaert Siri E Håberg Thorkild I A Sørensen Jack A Taylor Katri Räikkönen Ivana V Yang Katerina Kechris Tim S Nawrot Matt J Silver Yun Yun Gong Lorenzo Richiardi Manolis Kogevinas Augusto A Litonjua Brenda Eskenazi Karen Huen Hamdi Mbarek Rachel L Maguire Terence Dwyer Martine Vrijheid Luigi Bouchard Andrea A Baccarelli Lisa A Croen Wilfried Karmaus Denise Anderson Maaike de Vries Sylvain Sebert Juha Kere Robert Karlsson Syed Hasan Arshad Esa Hämäläinen Michael N Routledge Dorret I Boomsma Andrew P Feinberg Craig J Newschaffer Eva Govarts Matthieu Moisse M Daniele Fallin Erik Melén Andrew M Prentice Eero Kajantie Catarina Almqvist Emily Oken Dana Dabelea H Marike Boezen Phillip E Melton Rosalind J Wright Gerard H Koppelman Letizia Trevisi Marie-France Hivert Jordi Sunyer Monica C Munthe-Kaas Susan K Murphy Eva Corpeleijn Joseph Wiemels Nina Holland Zdenko Herceg Elisabeth B Binder George Davey Smith Vincent W V Jaddoe Rolv T Lie Wenche Nystad Stephanie J London Debbie A Lawlor Caroline L Relton Harold Snieder Janine F Felix

Nat Commun 2019 04 23;10(1):1893. Epub 2019 Apr 23.

The Generation R Study Group, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1038/s41467-019-09671-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6478731PMC
April 2019

Toxicological effects of regulated mycotoxins and persistent organochloride pesticides: In vitro cytotoxic assessment of single and defined mixtures on MA-10 murine Leydig cell line.

Toxicol In Vitro 2018 Apr 5;48:93-103. Epub 2018 Jan 5.

School of Food Science and Nutrition, Food Science Building, University of Leeds, LS2 9JT, UK.

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http://dx.doi.org/10.1016/j.tiv.2017.12.019DOI Listing
April 2018

Comparison of urinary aflatoxin M1 and aflatoxin albumin adducts as biomarkers for assessing aflatoxin exposure in Tanzanian children.

Biomarkers 2018 Mar 20;23(2):131-136. Epub 2017 Feb 20.

e LICAMM , School of Medicine, University of Leeds , Leeds, United Kingdom.

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http://dx.doi.org/10.1080/1354750X.2017.1285960DOI Listing
March 2018

Risk assessment of deoxynivalenol in high-risk area of China by human biomonitoring using an improved high throughput UPLC-MS/MS method.

Sci Rep 2018 03 1;8(1):3901. Epub 2018 Mar 1.

China National Center for Food Safety Risk Assessment, Key laboratory of Food Safety Risk Assessment, Ministry of Health, Beijing, 100021, PR China.

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http://dx.doi.org/10.1038/s41598-018-22206-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5832810PMC
March 2018

Urban Particulate Matter Induces Changes in Gene Expression in Vascular Endothelial Cells that Are Associated with Altered Clot Structure In Vitro.

Thromb Haemost 2018 02 29;118(2):266-278. Epub 2018 Jan 29.

Environmental Epidemiology Group, Leeds Institute for Cardiovascular and Metabolic Medicine, School of Medicine, University of Leeds, Leeds, United Kingdom.

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http://dx.doi.org/10.1160/TH17-05-0362DOI Listing
February 2018

Fibrin clot structure is affected by levels of particulate air pollution exposure in patients with venous thrombosis.

Environ Int 2016 Jul-Aug;92-93:70-6. Epub 2016 Apr 7.

Environmental Epidemiology, Leeds Institute for Cardiovascular and Metabolic Medicine, School of Medicine, University of Leeds, Leeds, UK.

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http://dx.doi.org/10.1016/j.envint.2016.03.030DOI Listing
June 2017

Study of an Educational Hand Sorting Intervention for Reducing Aflatoxin B in Groundnuts in Rural Gambia.

J Food Prot 2017 01;80(1):44-49

Institute for Global Food Security, School of Biological Sciences, Queen's University Belfast, Belfast BT7 1NN, UK.

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http://jfoodprotection.org/doi/10.4315/0362-028X.JFP-16-152
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http://dx.doi.org/10.4315/0362-028X.JFP-16-152DOI Listing
January 2017

Dietary exposure to aflatoxin and micronutrient status among young children from Guinea.

Mol Nutr Food Res 2016 Mar 18;60(3):511-8. Epub 2015 Dec 18.

Institute for Global Food Security, School of Biological Sciences, Queen's University Belfast, Belfast, UK.

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http://dx.doi.org/10.1002/mnfr.201500382DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4915736PMC
March 2016

A prospective study of growth and biomarkers of exposure to aflatoxin and fumonisin during early childhood in Tanzania.

Environ Health Perspect 2015 Feb 17;123(2):173-8. Epub 2014 Oct 17.

Division of Epidemiology, School of Medicine, University of Leeds, Leeds, United Kingdom.

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http://dx.doi.org/10.1289/ehp.1408097DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4314247PMC
February 2015

Quantitative correlation of aflatoxin biomarker with dietary intake of aflatoxin in Tanzanian children.

Biomarkers 2014 Aug 5;19(5):430-5. Epub 2014 Jun 5.

School of Medicine, University of Leeds , Leeds , UK .

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http://dx.doi.org/10.3109/1354750X.2014.924998DOI Listing
August 2014

Deoxynivalenol exposure assessment in young children in Tanzania.

Mol Nutr Food Res 2014 Jul 14;58(7):1574-80. Epub 2014 May 14.

School of Biological Sciences, Institute for Global Food Security, Queen's University Belfast, UK; Division of Epidemiology, Leeds Institute of Genetics, Health and Therapeutics, University of Leeds, UK.

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http://dx.doi.org/10.1002/mnfr.201400012DOI Listing
July 2014

A pilot study to evaluate aflatoxin exposure in a rural Ugandan population.

Trop Med Int Health 2014 May 24;19(5):592-9. Epub 2014 Feb 24.

Medical Research Council/Uganda Virus Research Institute, Research Unit on AIDS, Entebbe, Uganda.

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http://dx.doi.org/10.1111/tmi.12283DOI Listing
May 2014

Dietary exposure to aflatoxin and fumonisin among Tanzanian children as determined using biomarkers of exposure.

Mol Nutr Food Res 2013 Oct 17;57(10):1874-81. Epub 2013 Jun 17.

Division of Epidemiology, Leeds Institute of Genetics, Health and Therapeutics, University of Leeds, Leeds, UK; Tanzania Food and Drugs Authority (TFDA), Dar es Salaam, Tanzania; Department of Food Science and Technology, Sokoine University of Agriculture, Morogoro, Tanzania.

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http://dx.doi.org/10.1002/mnfr.201300116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4044922PMC
October 2013

Mechanism of cellular uptake of genotoxic silica nanoparticles.

Part Fibre Toxicol 2012 Jul 23;9:29. Epub 2012 Jul 23.

Centre for Molecular NanoScience (CMNS), University of Leeds, Leeds LS2 9JT, UK.

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http://dx.doi.org/10.1186/1743-8977-9-29DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3479067PMC
July 2012

Aflatoxin exposure may contribute to chronic hepatomegaly in Kenyan school children.

Environ Health Perspect 2012 Jun 27;120(6):893-6. Epub 2012 Feb 27.

Division of Epidemiology, Leeds Institute for Genetics, Health and Therapeutics, University of Leeds, Leeds, United Kingdom.

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http://dx.doi.org/10.1289/ehp.1104357DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3385435PMC
June 2012

Fibrin clot structure remains unaffected in young, healthy individuals after transient exposure to diesel exhaust.

Part Fibre Toxicol 2010 Jun 16;7:17. Epub 2010 Jun 16.

Division of Cardiovascular and Diabetes Research, Section on Mechanisms of Thrombosis, Leeds Institute for Genetics Health and Therapeutics, Faculty of Medicine and Health, University of Leeds, Leeds, UK.

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http://biomedcentral.com/content/pdf/1743-8977-7-17.pdf
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http://particleandfibretoxicology.biomedcentral.com/articles
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http://dx.doi.org/10.1186/1743-8977-7-17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2903495PMC
June 2010

Alteration of fibrin clot properties by ultrafine particulate matter.

Thromb Haemost 2010 Jan 30;103(1):103-13. Epub 2009 Sep 30.

Molecular Epidemiology Unit, Leeds Institute for Health, Genetics and Therapeutics, Faculty of Medicine and Health, University of Leeds, UK.

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http://dx.doi.org/10.1160/TH09-05-0330DOI Listing
January 2010

Influence of DNA repair gene polymorphisms on the initial repair of MMS-induced DNA damage in human lymphocytes as measured by the alkaline comet assay.

Environ Mol Mutagen 2008 Dec;49(9):669-75

Department of Biosciences and Nutrition, Karolinska Institute, 14157 Huddinge, Sweden.

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http://dx.doi.org/10.1002/em.20415DOI Listing
December 2008

Cellular prion protein protects against reactive-oxygen-species-induced DNA damage.

Free Radic Biol Med 2007 Sep 13;43(6):959-67. Epub 2007 Jun 13.

Proteolysis Research Group, Institute of Molecular and Cellular Biology, Faculty of Biological Sciences and Leeds Institute of Genetics, Health and Therapeutics, University of Leeds, Leeds LS2 9JT, UK.

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http://linkinghub.elsevier.com/retrieve/pii/S089158490700389
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http://dx.doi.org/10.1016/j.freeradbiomed.2007.06.004DOI Listing
September 2007

DNA methylation of GSTP1 as biomarker in diagnosis of prostate cancer.

Urology 2007 Jan;69(1):11-6

Molecular Epidemiology Unit, Centre for Epidemiology and Biostatistics, Leeds Institute for Genetics, Health and Therapeutics, University of Leeds, Leeds, United Kingdom.

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http://dx.doi.org/10.1016/j.urology.2006.10.008DOI Listing
January 2007

The mutagenicity of urban particulate matter in an enzyme free system is associated with the generation of reactive oxygen species.

Mutat Res 2006 Dec 14;602(1-2):1-6. Epub 2006 Aug 14.

Molecular Epidemiology Unit, Centre for Epidemiology & Biostatistics, Leeds Institute for Genetics Health & Therapeutics, The LIGHT Laboratories, University of Leeds, Leeds LS2 9JT, United Kingdom.

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http://dx.doi.org/10.1016/j.mrfmmm.2006.07.002DOI Listing
December 2006

Wavelength dependent responses of primary human keratinocytes to combined treatment with benzo[a]pyrene and UV light.

Mutagenesis 2005 Jul 14;20(4):305-10. Epub 2005 Jun 14.

Molecular Epidemiology Unit, Centre for Epidemiology and Biostatistics, Leeds Institute for Genetics, Health and Therapeutics and The School of Biochemistry and Microbiology, University of Leeds, Leeds LS2 9JT, UK.

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http://dx.doi.org/10.1093/mutage/gei042DOI Listing
July 2005

Mutation spectra induced by alpha-acetoxytamoxifen-DNA adducts in human DNA repair proficient and deficient (xeroderma pigmentosum complementation group A) cells.

Biochemistry 2005 Jun;44(22):8198-205

Cancer Biomarkers and Prevention Group, Department of Cancer Studies and Molecular Medicine, The Biocentre, University of Leicester, University Road, Leicester, LE1 7RH, United Kingdom.

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http://dx.doi.org/10.1021/bi047399eDOI Listing
June 2005

Genotoxicity of size-fractionated samples of urban particulate matter.

Environ Mol Mutagen 2005 May;45(4):380-7

Molecular Epidemiology Unit, Centre for Epidemiology and Biostatistics, University of Leeds, Leeds, United Kingdom.

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http://dx.doi.org/10.1002/em.20105DOI Listing
May 2005

Effects of the order of exposure to a binary mixture of mutagens on the induced mutation spectra in the supF gene.

Mutagenesis 2004 Mar;19(2):137-41

Cancer Biomarkers and Prevention Group, The Biocentre, University of Leicester, University Road, Leicester LE1 7RH, UK.

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http://dx.doi.org/10.1093/mutage/geh011DOI Listing
March 2004

Binary exposure of A549 cells to benzo[a]pyrene and UVC radiation yields enhanced DNA damage in the comet assay but no enhancement of 8-oxo-deoxyguanosine.

Environ Mol Mutagen 2003 ;42(3):228-30

Department of Experimental and Applied Genetics, Institute of Preventive and Clinical Medicine, Bratislava, Slovakia.

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http://dx.doi.org/10.1002/em.10191DOI Listing
December 2003

DNA adducts formed from 4-hydroxytamoxifen are more mutagenic than those formed by alpha-acetoxytamoxifen in a shuttle vector target gene replicated in human Ad293 cells.

Biochemistry 2002 Jul;41(28):8899-906

Cancer Biomarkers and Prevention Group, The Biocentre, University of Leicester, University Road, Leicester, LE1 7RH, U.K.

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http://dx.doi.org/10.1021/bi025575iDOI Listing
July 2002