Michael Morley

Michael Morley

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Michael Morley

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Dnmt1 is required for proximal-distal patterning of the lung endoderm and for restraining alveolar type 2 cell fate.

Dev Biol 2019 Jun 23. Epub 2019 Jun 23.

Department of Cell and Developmental Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA; Penn Cardiovascular Institute, University of Pennsylvania, Philadelphia, PA, 19104, USA; Penn Center for Pulmonary Biology, University of Pennsylvania, Philadelphia, PA, 19104, USA; Department of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA; Penn-CHOP Lung Biology Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ydbio.2019.06.019DOI Listing
June 2019

Ocular angiostrongyliasis in Thailand: a retrospective analysis over two decades.

Clin Ophthalmol 2019 18;13:1027-1031. Epub 2019 Jun 18.

KKU Eye Center, Department of Ophthalmology, Khon Kaen University, Khon Kaen, Thailand.

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http://dx.doi.org/10.2147/OPTH.S204380DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6592067PMC
June 2019

Identification of a mesenchymal progenitor cell hierarchy in adipose tissue.

Science 2019 04;364(6438)

Institute for Diabetes, Obesity and Metabolism, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA 19104, USA.

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http://www.sciencemag.org/lookup/doi/10.1126/science.aav2501
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http://dx.doi.org/10.1126/science.aav2501DOI Listing
April 2019

Cardioprotective Effects of MTSS1 Enhancer Variants.

Circulation 2019 Apr;139(17):2073-2076

Division of Cardiovascular Medicine and Penn Cardiovascular Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia (M.P.P., X.W., R.H., J.B., K.B.M., K.M., T.P.C.).

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https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.118.0
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http://dx.doi.org/10.1161/CIRCULATIONAHA.118.037939DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6510256PMC
April 2019

NADPH production by the oxidative pentose-phosphate pathway supports folate metabolism.

Nat Metab 2019 Mar 11;1:404-415. Epub 2019 Mar 11.

Department of Chemistry, Princeton University, Princeton, New Jersey 08544, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6489125PMC
March 2019

In Response.

Anesth Analg 2019 Jan;128(1):e11-e12

Department of Anaesthesia, Critical Care and Pain Medicine, Harvard Medical School, Massachusetts General Hospital, Boston, Massachusetts, Betsy Lehman Center for Patient Safety, Boston, Massachusetts Department of Ophthalmology, Harvard Medical School, Boston, Massachusetts, Ophthalmic Consultants of Boston, Boston, Massachusetts Department of Anesthesia, Massachusetts Eye & Ear, Department of Anaesthesia, Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1213/ANE.0000000000003872DOI Listing
January 2019

Thyroid Dysfunction in Heart Failure and Cardiovascular Outcomes.

Circ Heart Fail 2018 12;11(12):e005266

Division of Endocrinology, Diabetes, and Metabolism (L.K., A.R.C.) at the Perelman School of Medicine at the University of Pennsylvania, Philadelphia.

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http://dx.doi.org/10.1161/CIRCHEARTFAILURE.118.005266DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6352308PMC
December 2018

Multimedia Appendix Removal and Editorial Warning Regarding the MMAS Scale (Two-Way Social Media Messaging in Post-Operative Cataract Surgical Patients: A Prospective Interventional Study).

J Med Internet Res 2018 Dec 20;20(12):e12120. Epub 2018 Dec 20.

Data Management and Statistical Analysis Center, Faculty of Public Health, Khon Kaen University, Khon Kaen, Thailand.

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http://dx.doi.org/10.2196/12120DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6320430PMC
December 2018

In Response.

Anesth Analg 2018 10;127(4):e69-e70

Department of Anaesthesia, Harvard Medical School, Massachusetts General Hospital, Department of Anesthesia, Critical Care and Pain Medicine, Boston, Massachusetts, Betsy Lehman Center for Patient Safety, Boston, Massachusetts Ophthalmic Consultants of Boston, Department of Ophthalmology, Harvard Medical School, Boston, Massachusetts Department of Anesthesia, Massachusetts Eye & Ear, Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1213/ANE.0000000000003658DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6657337PMC
October 2018

In Response.

Anesth Analg 2018 10;127(4):e67-e68

Department of Anaesthesia, Harvard Medical School, Massachusetts General Hospital Department of AnesthesiaCritical Care and Pain Medicine, Boston, Massachusetts, Betsy Lehman Center for Patient Safety, Boston, Massachusetts Ophthalmic Consultants of Boston, Department of Ophthalmology, Harvard Medical School, Boston, Massachusetts Department of Anesthesia, Massachusetts Eye & Ear, Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1213/ANE.0000000000003656DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6657338PMC
October 2018

Suppression of detyrosinated microtubules improves cardiomyocyte function in human heart failure.

Nat Med 2018 08 11;24(8):1225-1233. Epub 2018 Jun 11.

Department of Physiology, Pennsylvania Muscle Institute, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.

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http://dx.doi.org/10.1038/s41591-018-0046-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6195768PMC
August 2018

Multi-ethnic genome-wide association study for atrial fibrillation.

Authors:
Carolina Roselli Mark D Chaffin Lu-Chen Weng Stefanie Aeschbacher Gustav Ahlberg Christine M Albert Peter Almgren Alvaro Alonso Christopher D Anderson Krishna G Aragam Dan E Arking John Barnard Traci M Bartz Emelia J Benjamin Nathan A Bihlmeyer Joshua C Bis Heather L Bloom Eric Boerwinkle Erwin B Bottinger Jennifer A Brody Hugh Calkins Archie Campbell Thomas P Cappola John Carlquist Daniel I Chasman Lin Y Chen Yii-Der Ida Chen Eue-Keun Choi Seung Hoan Choi Ingrid E Christophersen Mina K Chung John W Cole David Conen James Cook Harry J Crijns Michael J Cutler Scott M Damrauer Brian R Daniels Dawood Darbar Graciela Delgado Joshua C Denny Martin Dichgans Marcus Dörr Elton A Dudink Samuel C Dudley Nada Esa Tonu Esko Markku Eskola Diane Fatkin Stephan B Felix Ian Ford Oscar H Franco Bastiaan Geelhoed Raji P Grewal Vilmundur Gudnason Xiuqing Guo Namrata Gupta Stefan Gustafsson Rebecca Gutmann Anders Hamsten Tamara B Harris Caroline Hayward Susan R Heckbert Jussi Hernesniemi Lynne J Hocking Albert Hofman Andrea R V R Horimoto Jie Huang Paul L Huang Jennifer Huffman Erik Ingelsson Esra Gucuk Ipek Kaoru Ito Jordi Jimenez-Conde Renee Johnson J Wouter Jukema Stefan Kääb Mika Kähönen Yoichiro Kamatani John P Kane Adnan Kastrati Sekar Kathiresan Petra Katschnig-Winter Maryam Kavousi Thorsten Kessler Bas L Kietselaer Paulus Kirchhof Marcus E Kleber Stacey Knight Jose E Krieger Michiaki Kubo Lenore J Launer Jari Laurikka Terho Lehtimäki Kirsten Leineweber Rozenn N Lemaitre Man Li Hong Euy Lim Henry J Lin Honghuang Lin Lars Lind Cecilia M Lindgren Marja-Liisa Lokki Barry London Ruth J F Loos Siew-Kee Low Yingchang Lu Leo-Pekka Lyytikäinen Peter W Macfarlane Patrik K Magnusson Anubha Mahajan Rainer Malik Alfredo J Mansur Gregory M Marcus Lauren Margolin Kenneth B Margulies Winfried März David D McManus Olle Melander Sanghamitra Mohanty Jay A Montgomery Michael P Morley Andrew P Morris Martina Müller-Nurasyid Andrea Natale Saman Nazarian Benjamin Neumann Christopher Newton-Cheh Maartje N Niemeijer Kjell Nikus Peter Nilsson Raymond Noordam Heidi Oellers Morten S Olesen Marju Orho-Melander Sandosh Padmanabhan Hui-Nam Pak Guillaume Paré Nancy L Pedersen Joanna Pera Alexandre Pereira David Porteous Bruce M Psaty Sara L Pulit Clive R Pullinger Daniel J Rader Lena Refsgaard Marta Ribasés Paul M Ridker Michiel Rienstra Lorenz Risch Dan M Roden Jonathan Rosand Michael A Rosenberg Natalia Rost Jerome I Rotter Samir Saba Roopinder K Sandhu Renate B Schnabel Katharina Schramm Heribert Schunkert Claudia Schurman Stuart A Scott Ilkka Seppälä Christian Shaffer Svati Shah Alaa A Shalaby Jaemin Shim M Benjamin Shoemaker Joylene E Siland Juha Sinisalo Moritz F Sinner Agnieszka Slowik Albert V Smith Blair H Smith J Gustav Smith Jonathan D Smith Nicholas L Smith Elsayed Z Soliman Nona Sotoodehnia Bruno H Stricker Albert Sun Han Sun Jesper H Svendsen Toshihiro Tanaka Kahraman Tanriverdi Kent D Taylor Maris Teder-Laving Alexander Teumer Sébastien Thériault Stella Trompet Nathan R Tucker Arnljot Tveit Andre G Uitterlinden Pim Van Der Harst Isabelle C Van Gelder David R Van Wagoner Niek Verweij Efthymia Vlachopoulou Uwe Völker Biqi Wang Peter E Weeke Bob Weijs Raul Weiss Stefan Weiss Quinn S Wells Kerri L Wiggins Jorge A Wong Daniel Woo Bradford B Worrall Pil-Sung Yang Jie Yao Zachary T Yoneda Tanja Zeller Lingyao Zeng Steven A Lubitz Kathryn L Lunetta Patrick T Ellinor

Nat Genet 2018 06 11;50(9):1225-1233. Epub 2018 Jun 11.

Program in Medical and Population Genetics, The Broad Institute of MIT and Harvard, Cambridge, MA, USA.

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http://dx.doi.org/10.1038/s41588-018-0133-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6136836PMC
June 2018

Patient Harm in Cataract Surgery: A Series of Adverse Events in Massachusetts.

Anesth Analg 2018 05;126(5):1548-1550

Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Harvard University, Boston, Massachusetts.

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http://dx.doi.org/10.1213/ANE.0000000000002526DOI Listing
May 2018

Preventing Adverse Events in Cataract Surgery: Recommendations From a Massachusetts Expert Panel.

Anesth Analg 2018 05;126(5):1537-1547

Department of Anesthesia, Massachusetts Eye & Ear, Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1213/ANE.0000000000002529DOI Listing
May 2018

Single-Cell Transcriptomic Profiling of Pluripotent Stem Cell-Derived SCGB3A2+ Airway Epithelium.

Stem Cell Reports 2018 05 12;10(5):1579-1595. Epub 2018 Apr 12.

Center for Regenerative Medicine of Boston University and Boston Medical Center, Boston, MA 02118, USA; The Pulmonary Center and Department of Medicine, Boston University School of Medicine, Boston, MA 02118, USA. Electronic address:

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http://dx.doi.org/10.1016/j.stemcr.2018.03.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5995784PMC
May 2018

Regeneration of the lung alveolus by an evolutionarily conserved epithelial progenitor.

Nature 2018 03 28;555(7695):251-255. Epub 2018 Feb 28.

Department of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.

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http://dx.doi.org/10.1038/nature25786DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6020060PMC
March 2018

Genetic Reduction in Left Ventricular Protein Kinase C-α and Adverse Ventricular Remodeling in Human Subjects.

Circ Genom Precis Med 2018 03;11(3):e001901

From the Penn Cardiovascular Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia (R.H., M.P.M., J.B., K.B.M., T.P.C.); Cardiovascular Research Center (N.R.T., V.A.P., P.T.E.) and Center for Human Genetic Research and Cardiovascular Research Center (C.N.-C.), Massachusetts General Hospital, Boston; Department of Statistics, University of Illinois at Urbana-Champaign (S.D.Z.); Heidelberg University Hospital, Germany (B.M., H.A.K.); Department of Genetic Epidemiology, Institute of Human Genetics, University of Münster, Germany (F.R., M.S.); INSERM UMRS1166-IACN, Hôpital Pitié-Salpêtrière, Paris, France (E.V., F.C.); Section of Computational Biomedicine, Department of Medicine, Boston University School of Medicine, MA (H.L.); Department of Epidemiology, University of Washington, Seattle (N.L.S.); Department of Epidemiology, Erasmus MC, University Medical Center Rotterdam, the Netherlands (J.F.F.); Boston University School of Medicine, MA (R.S.V.); Department of Cardiology, University of Groningen, University Medical Center Groningen, the Netherlands (P.v.d.H.); Medical and Population Genetics Program, Broad Institute, Cambridge, MA (C.N.-C.); Center for Applied Genomics, Children's Hospital of Philadelphia, PA (J.L., C.E.K., H.H.); Center for Bioinformatics and Computational Biology, University of Maryland, College Park (S.H.); Stanford Center for Inherited Cardiovascular Disease, Stanford University School of Medicine, CA (E.A.A.); Department of Cardiovascular Medicine, Cleveland Clinic, OH (C.S.M., W.H.W.T.); and Howard Hughes Medical Institute and Cincinnati Children's Hospital Medical Center, OH (M.M., J.D.M.).

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http://dx.doi.org/10.1161/CIRCGEN.117.001901DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5858599PMC
March 2018

PDK4 Inhibits Cardiac Pyruvate Oxidation in Late Pregnancy.

Circ Res 2017 Dec 19;121(12):1370-1378. Epub 2017 Sep 19.

From the Cardiovascular Institute, Beth Israel Deaconess Medical Center, Boston, MA (L.X.L., F.D.); Corrigan Minehan Heart Center, Massachusetts General Hospital, Boston (L.X.L., F.D., M.C.C., S.D., A.R.); Division of Cardiovascular Disease, University of Alabama at Birmingham (G.C.R.); Cardiovascular Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia (S.Y., J.L., S.W., M.M., Z.A.); Lewis-Sigler Institute for Integrative Genomics, Princeton University, NJ (W.L., C.J., J.D.R.); and Institute of Physiology I, Life and Brain Center, Medical Faculty, University of Bonn, Germany (M.H., B.K.F.).

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http://dx.doi.org/10.1161/CIRCRESAHA.117.311456DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5722682PMC
December 2017

Differentiation of Human Pluripotent Stem Cells into Functional Lung Alveolar Epithelial Cells.

Cell Stem Cell 2017 10 28;21(4):472-488.e10. Epub 2017 Sep 28.

Center for Regenerative Medicine of Boston University and Boston Medical Center, Boston, MA 02118, USA; The Pulmonary Center and Department of Medicine, Boston University School of Medicine, Boston, MA 02118, USA. Electronic address:

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http://dx.doi.org/10.1016/j.stem.2017.08.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5755620PMC
October 2017

Genome-Nuclear Lamina Interactions Regulate Cardiac Stem Cell Lineage Restriction.

Cell 2017 Oct 12;171(3):573-587.e14. Epub 2017 Oct 12.

Departments of Medicine and Cell and Developmental Biology, Institute for Regenerative Medicine, and the Penn Cardiovascular Institute, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA 19104, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2017.09.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5683101PMC
October 2017

Distinct Mesenchymal Lineages and Niches Promote Epithelial Self-Renewal and Myofibrogenesis in the Lung.

Cell 2017 Sep;170(6):1134-1148.e10

Department of Medicine, Division of Pediatric Cardiology, Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA; Department of Cell and Developmental Biology, University of Pennsylvania, Philadelphia, PA 19104, USA; Penn Center for Pulmonary Biology, University of Pennsylvania, Philadelphia, PA 19104, USA; Penn Cardiovascular Institute, University of Pennsylvania, Philadelphia, PA 19104, USA; Penn Institute for Regenerative Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00928674173087
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http://dx.doi.org/10.1016/j.cell.2017.07.034DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5718193PMC
September 2017

Large-scale genome-wide analysis identifies genetic variants associated with cardiac structure and function.

Authors:
Philipp S Wild Janine F Felix Arne Schillert Alexander Teumer Ming-Huei Chen Maarten J G Leening Uwe Völker Vera Großmann Jennifer A Brody Marguerite R Irvin Sanjiv J Shah Setia Pramana Wolfgang Lieb Reinhold Schmidt Alice V Stanton Dörthe Malzahn Albert Vernon Smith Johan Sundström Cosetta Minelli Daniela Ruggiero Leo-Pekka Lyytikäinen Daniel Tiller J Gustav Smith Claire Monnereau Marco R Di Tullio Solomon K Musani Alanna C Morrison Tune H Pers Michael Morley Marcus E Kleber Jayashri Aragam Emelia J Benjamin Joshua C Bis Egbert Bisping Ulrich Broeckel Susan Cheng Jaap W Deckers Fabiola Del Greco M Frank Edelmann Myriam Fornage Lude Franke Nele Friedrich Tamara B Harris Edith Hofer Albert Hofman Jie Huang Alun D Hughes Mika Kähönen Knhi Investigators Jochen Kruppa Karl J Lackner Lars Lannfelt Rafael Laskowski Lenore J Launer Margrét Leosdottir Honghuang Lin Cecilia M Lindgren Christina Loley Calum A MacRae Deborah Mascalzoni Jamil Mayet Daniel Medenwald Andrew P Morris Christian Müller Martina Müller-Nurasyid Stefania Nappo Peter M Nilsson Sebastian Nuding Teresa Nutile Annette Peters Arne Pfeufer Diana Pietzner Peter P Pramstaller Olli T Raitakari Kenneth M Rice Fernando Rivadeneira Jerome I Rotter Saku T Ruohonen Ralph L Sacco Tandaw E Samdarshi Helena Schmidt Andrew S P Sharp Denis C Shields Rossella Sorice Nona Sotoodehnia Bruno H Stricker Praveen Surendran Simon Thom Anna M Töglhofer André G Uitterlinden Rolf Wachter Henry Völzke Andreas Ziegler Thomas Münzel Winfried März Thomas P Cappola Joel N Hirschhorn Gary F Mitchell Nicholas L Smith Ervin R Fox Nicole D Dueker Vincent W V Jaddoe Olle Melander Martin Russ Terho Lehtimäki Marina Ciullo Andrew A Hicks Lars Lind Vilmundur Gudnason Burkert Pieske Anthony J Barron Robert Zweiker Heribert Schunkert Erik Ingelsson Kiang Liu Donna K Arnett Bruce M Psaty Stefan Blankenberg Martin G Larson Stephan B Felix Oscar H Franco Tanja Zeller Ramachandran S Vasan Marcus Dörr

J Clin Invest 2017 May 10;127(5):1798-1812. Epub 2017 Apr 10.

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https://www.jci.org/articles/view/84840
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http://dx.doi.org/10.1172/JCI84840DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5409098PMC
May 2017

Reply.

Ophthalmology 2017 03;124(3):e28

Ophthalmic Consultants of Boston, Retina Service, Boston, Massachusetts.

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http://dx.doi.org/10.1016/j.ophtha.2016.05.050DOI Listing
March 2017

The relationship between gender role stereotypes and requisite managerial characteristics: The case of nursing and midwifery professionals: a response to Lalor.

J Nurs Manag 2016 11 21;24(8):1137-1140. Epub 2016 Jul 21.

Department of Management and Marketing, Kemmy Business School, University of Limerick, Limerick, Ireland.

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http://doi.wiley.com/10.1111/jonm.12410
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http://dx.doi.org/10.1111/jonm.12410DOI Listing
November 2016

Emergence of a Wave of Wnt Signaling that Regulates Lung Alveologenesis by Controlling Epithelial Self-Renewal and Differentiation.

Cell Rep 2016 11;17(9):2312-2325

Department of Cell and Developmental Biology, University of Pennsylvania, Philadelphia, PA 19104, USA; Penn Cardiovascular Institute, University of Pennsylvania, Philadelphia, PA 19104, USA; Penn Center for Pulmonary Biology, University of Pennsylvania, Philadelphia, PA 19104, USA; Penn Institute for Regenerative Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2016.11.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5214982PMC
November 2016

The tumor suppressor FLCN mediates an alternate mTOR pathway to regulate browning of adipose tissue.

Genes Dev 2016 11 2;30(22):2551-2564. Epub 2016 Dec 2.

Department of Medicine and Cardiovascular Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.

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http://dx.doi.org/10.1101/gad.287953.116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5159669PMC
November 2016

Foxp transcription factors suppress a non-pulmonary gene expression program to permit proper lung development.

Dev Biol 2016 08 21;416(2):338-46. Epub 2016 Jun 21.

Department of Medicine, University of Pennsylvania, Philadelphia, PA 19104, United States; Penn Center for Pulmonary Biology, University of Pennsylvania, Philadelphia, PA 19104, United States; Cardiovascular Institute, University of Pennsylvania, Philadelphia, PA 19104, United States; Department of Cell and Developmental Biology, University of Pennsylvania, Philadelphia, PA 19104, United States; Institute for Regenerative Medicine, University of Pennsylvania, Philadelphia, PA 19104, United States. Electronic address:

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http://dx.doi.org/10.1016/j.ydbio.2016.06.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4983242PMC
August 2016

Outcomes after Failed Pneumatic Retinopexy for Retinal Detachment.

Ophthalmology 2016 May 5;123(5):1137-42. Epub 2016 Mar 5.

Ophthalmic Consultants of Boston, Boston, Massachusetts.

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http://dx.doi.org/10.1016/j.ophtha.2016.01.017DOI Listing
May 2016

Causal Assessment of Serum Urate Levels in Cardiometabolic Diseases Through a Mendelian Randomization Study.

J Am Coll Cardiol 2016 Feb;67(4):407-416

Translational Medicine and Human Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania; Center for Non-Communicable Diseases, Karachi, Pakistan; Department of Biostatistics and Epidemiology, University of Pennsylvania, Philadelphia, Pennsylvania. Electronic address:

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http://content.onlinejacc.org/data/Journals/JAC/934865/10086
Web Search
http://linkinghub.elsevier.com/retrieve/pii/S073510971507523
Publisher Site
http://dx.doi.org/10.1016/j.jacc.2015.10.086DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5503188PMC
February 2016

HDAC3-Dependent Epigenetic Pathway Controls Lung Alveolar Epithelial Cell Remodeling and Spreading via miR-17-92 and TGF-β Signaling Regulation.

Dev Cell 2016 Feb 28;36(3):303-15. Epub 2016 Jan 28.

Department of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA; Penn Cardiovascular Institute, University of Pennsylvania, Philadelphia, PA 19104, USA; Penn Center for Pulmonary Biology, University of Pennsylvania, Philadelphia, PA 19104, USA; Department of Cell and Developmental Biology, University of Pennsylvania, Philadelphia, PA 19104, USA; Penn Institute for Regenerative Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA; Translational Research Center, University of Pennsylvania, Room 11-124, 3400 Civic Center Boulevard, Building 421, Philadelphia, PA 19104-5129, USA. Electronic address:

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http://dx.doi.org/10.1016/j.devcel.2015.12.031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4750387PMC
February 2016

Hedgehog actively maintains adult lung quiescence and regulates repair and regeneration.

Nature 2015 Oct 5;526(7574):578-82. Epub 2015 Oct 5.

Department of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.

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http://dx.doi.org/10.1038/nature14984DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4713039PMC
October 2015

Bayesian integration of genetics and epigenetics detects causal regulatory SNPs underlying expression variability.

Nat Commun 2015 Oct 12;6:8555. Epub 2015 Oct 12.

Center for Bioinformatics and Computational Biology, University of Maryland, College Park, Maryland 20742, USA.

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http://dx.doi.org/10.1038/ncomms9555DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4633824PMC
October 2015

A microRNA-Hippo pathway that promotes cardiomyocyte proliferation and cardiac regeneration in mice.

Sci Transl Med 2015 Mar;7(279):279ra38

Department of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA. Department of Cell and Developmental Biology, University of Pennsylvania, Philadelphia, PA19104, USA. Institute for Regenerative Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA. Cardiovascular Institute, University of Pennsylvania, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1126/scitranslmed.3010841DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6295313PMC
March 2015

RNA-Seq identifies novel myocardial gene expression signatures of heart failure.

Genomics 2015 Feb 17;105(2):83-9. Epub 2014 Dec 17.

Department of Biostatistics and Epidemiology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104, United States. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S08887543140026
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http://dx.doi.org/10.1016/j.ygeno.2014.12.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4684258PMC
February 2015

Ezh2 represses the basal cell lineage during lung endoderm development.

Development 2015 Jan;142(1):108-17

Department of Cell and Developmental Biology, University of Pennsylvania, Philadelphia, PA 19104, USA Department of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA Cardiovascular Institute, University of Pennsylvania, Philadelphia, PA 19104, USA Institute for Regenerative Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA

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http://dx.doi.org/10.1242/dev.116947DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4299135PMC
January 2015

The relationship between gender role stereotypes and requisite managerial characteristics: the case of nursing and midwifery professionals.

J Nurs Manag 2014 Sep 2;22(6):707-19. Epub 2012 Nov 2.

Department of Management and Marketing, Kemmy Business School, University of Limerick, Limerick, Ireland.

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http://doi.wiley.com/10.1111/j.1365-2834.2012.01459.x
Publisher Site
http://dx.doi.org/10.1111/j.1365-2834.2012.01459.xDOI Listing
September 2014

Genetic association study of QT interval highlights role for calcium signaling pathways in myocardial repolarization.

Authors:
Dan E Arking Sara L Pulit Lia Crotti Pim van der Harst Patricia B Munroe Tamara T Koopmann Nona Sotoodehnia Elizabeth J Rossin Michael Morley Xinchen Wang Andrew D Johnson Alicia Lundby Daníel F Gudbjartsson Peter A Noseworthy Mark Eijgelsheim Yuki Bradford Kirill V Tarasov Marcus Dörr Martina Müller-Nurasyid Annukka M Lahtinen Ilja M Nolte Albert Vernon Smith Joshua C Bis Aaron Isaacs Stephen J Newhouse Daniel S Evans Wendy S Post Daryl Waggott Leo-Pekka Lyytikäinen Andrew A Hicks Lewin Eisele David Ellinghaus Caroline Hayward Pau Navarro Sheila Ulivi Toshiko Tanaka David J Tester Stéphanie Chatel Stefan Gustafsson Meena Kumari Richard W Morris Åsa T Naluai Sandosh Padmanabhan Alexander Kluttig Bernhard Strohmer Andrie G Panayiotou Maria Torres Michael Knoflach Jaroslav A Hubacek Kamil Slowikowski Soumya Raychaudhuri Runjun D Kumar Tamara B Harris Lenore J Launer Alan R Shuldiner Alvaro Alonso Joel S Bader Georg Ehret Hailiang Huang W H Linda Kao James B Strait Peter W Macfarlane Morris Brown Mark J Caulfield Nilesh J Samani Florian Kronenberg Johann Willeit J Gustav Smith Karin H Greiser Henriette Meyer Zu Schwabedissen Karl Werdan Massimo Carella Leopoldo Zelante Susan R Heckbert Bruce M Psaty Jerome I Rotter Ivana Kolcic Ozren Polašek Alan F Wright Maura Griffin Mark J Daly David O Arnar Hilma Hólm Unnur Thorsteinsdottir Joshua C Denny Dan M Roden Rebecca L Zuvich Valur Emilsson Andrew S Plump Martin G Larson Christopher J O'Donnell Xiaoyan Yin Marco Bobbo Adamo P D'Adamo Annamaria Iorio Gianfranco Sinagra Angel Carracedo Steven R Cummings Michael A Nalls Antti Jula Kimmo K Kontula Annukka Marjamaa Lasse Oikarinen Markus Perola Kimmo Porthan Raimund Erbel Per Hoffmann Karl-Heinz Jöckel Hagen Kälsch Markus M Nöthen Marcel den Hoed Ruth J F Loos Dag S Thelle Christian Gieger Thomas Meitinger Siegfried Perz Annette Peters Hanna Prucha Moritz F Sinner Melanie Waldenberger Rudolf A de Boer Lude Franke Pieter A van der Vleuten Britt Maria Beckmann Eimo Martens Abdennasser Bardai Nynke Hofman Arthur A M Wilde Elijah R Behr Chrysoula Dalageorgou John R Giudicessi Argelia Medeiros-Domingo Julien Barc Florence Kyndt Vincent Probst Alice Ghidoni Roberto Insolia Robert M Hamilton Stephen W Scherer Jeffrey Brandimarto Kenneth Margulies Christine E Moravec Fabiola del Greco M Christian Fuchsberger Jeffrey R O'Connell Wai K Lee Graham C M Watt Harry Campbell Sarah H Wild Nour E El Mokhtari Norbert Frey Folkert W Asselbergs Irene Mateo Leach Gerjan Navis Maarten P van den Berg Dirk J van Veldhuisen Manolis Kellis Bouwe P Krijthe Oscar H Franco Albert Hofman Jan A Kors André G Uitterlinden Jacqueline C M Witteman Lyudmyla Kedenko Claudia Lamina Ben A Oostra Gonçalo R Abecasis Edward G Lakatta Antonella Mulas Marco Orrú David Schlessinger Manuela Uda Marcello R P Markus Uwe Völker Harold Snieder Timothy D Spector Johan Ärnlöv Lars Lind Johan Sundström Ann-Christine Syvänen Mika Kivimaki Mika Kähönen Nina Mononen Olli T Raitakari Jorma S Viikari Vera Adamkova Stefan Kiechl Maria Brion Andrew N Nicolaides Bernhard Paulweber Johannes Haerting Anna F Dominiczak Fredrik Nyberg Peter H Whincup Aroon D Hingorani Jean-Jacques Schott Connie R Bezzina Erik Ingelsson Luigi Ferrucci Paolo Gasparini James F Wilson Igor Rudan Andre Franke Thomas W Mühleisen Peter P Pramstaller Terho J Lehtimäki Andrew D Paterson Afshin Parsa Yongmei Liu Cornelia M van Duijn David S Siscovick Vilmundur Gudnason Yalda Jamshidi Veikko Salomaa Stephan B Felix Serena Sanna Marylyn D Ritchie Bruno H Stricker Kari Stefansson Laurie A Boyer Thomas P Cappola Jesper V Olsen Kasper Lage Peter J Schwartz Stefan Kääb Aravinda Chakravarti Michael J Ackerman Arne Pfeufer Paul I W de Bakker Christopher Newton-Cheh

Nat Genet 2014 Aug 22;46(8):826-36. Epub 2014 Jun 22.

1] Center for Human Genetic Research, Massachusetts General Hospital, Boston, Massachusetts, USA. [2] Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA. [3] Harvard Medical School, Boston, Massachusetts, USA. [4] Cardiovascular Research Center, Massachusetts General Hospital, Boston, Massachusetts, USA. [5].

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