Michael Lubbert

Michael Lubbert

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Michael Lubbert

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Combination treatment of acute myeloid leukemia cells with DNMT and HDAC inhibitors: predominant synergistic gene downregulation associated with gene body demethylation.

Leukemia 2019 04 23;33(4):945-956. Epub 2018 Nov 23.

Division of Hematology, Oncology and Stem Cell Transplantation, Department of Internal Medicine, Faculty of Medicine and Medical Center, University of Freiburg, Freiburg, Germany.

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http://dx.doi.org/10.1038/s41375-018-0293-8DOI Listing
April 2019

10-day vs 5-day decitabine: equivalence cannot be concluded.

Lancet Haematol 2019 04;6(4):e177

Department of Hematology, Freiburg University Hospital, Freiburg, Germany.

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https://linkinghub.elsevier.com/retrieve/pii/S23523026193002
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http://dx.doi.org/10.1016/S2352-3026(19)30024-9DOI Listing
April 2019

Can we predict responsiveness to hypomethylating agents in AML?

Semin Hematol 2019 Apr 27;56(2):118-124. Epub 2019 Feb 27.

Department of Hematology, Oncology, and Stem Cell Transplantation, Faculty of Medicine and Medical Center-University of Freiburg, Freiburg, Germany; German Cancer Research Consortium (DKTK), Freiburg, Germany. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00371963183012
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http://dx.doi.org/10.1053/j.seminhematol.2019.02.001DOI Listing
April 2019

Decitabine in combination with donor lymphocyte infusions can induce remissions in relapsed myeloid malignancies with higher leukemic burden after allogeneic hematopoietic cell transplantation.

Leuk Res 2018 09 7;72:20-26. Epub 2018 Jul 7.

Department of Hematology, Oncology and Stem Cell Transplantation, University of Freiburg Medical Center, Freiburg, Germany; German Cancer Consortium (DKTK), Freiburg, Germany; German Cancer Research Center (DKFZ), Heidelberg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.leukres.2018.07.005DOI Listing
September 2018

DNA-hypomethylating agents as epigenetic therapy before and after allogeneic hematopoietic stem cell transplantation in myelodysplastic syndromes and juvenile myelomonocytic leukemia.

Semin Cancer Biol 2018 08 9;51:68-79. Epub 2017 Nov 9.

Department of Hematology-Oncology, Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany; German Cancer Consortium (DKTK), Freiburg, Germany; German Cancer Research Center (DKFZ), Heidelberg, Germany.

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http://dx.doi.org/10.1016/j.semcancer.2017.10.011DOI Listing
August 2018

Effects of all-trans retinoic acid (ATRA) in addition to chemotherapy for adults with acute myeloid leukaemia (AML) (non-acute promyelocytic leukaemia (non-APL)).

Cochrane Database Syst Rev 2018 08 6;8:CD011960. Epub 2018 Aug 6.

Cochrane Haematological Malignancies Group, Department I of Internal Medicine, University Hospital of Cologne, Cologne, Germany.

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http://dx.doi.org/10.1002/14651858.CD011960.pub2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6513628PMC
August 2018

Erratum: Sorafenib promotes graft-versus-leukemia activity in mice and humans through IL-15 production in FLT3-ITD-mutant leukemia cells.

Authors:
Nimitha R Mathew Francis Baumgartner Lukas Braun David O'Sullivan Simone Thomas Miguel Waterhouse Tony A Müller Kathrin Hanke Sanaz Taromi Petya Apostolova Anna L Illert Wolfgang Melchinger Sandra Duquesne Annette Schmitt-Graeff Lena Osswald Kai-Li Yan Arnim Weber Sonia Tugues Sabine Spath Dietmar Pfeifer Marie Follo Rainer Claus Michael Lübbert Christoph Rummelt Hartmut Bertz Ralph Wäsch Johanna Haag Andrea Schmidts Michael Schultheiss Dominik Bettinger Robert Thimme Evelyn Ullrich Yakup Tanriver Giang Lam Vuong Renate Arnold Philipp Hemmati Dominik Wolf Markus Ditschkowski Cordula Jilg Konrad Wilhelm Christian Leiber Sabine Gerull Jörg Halter Claudia Lengerke Thomas Pabst Thomas Schroeder Guido Kobbe Wolf Rösler Soroush Doostkam Stephan Meckel Kathleen Stabla Stephan K Metzelder Sebastian Halbach Tilman Brummer Zehan Hu Joern Dengjel Björn Hackanson Christoph Schmid Udo Holtick Christof Scheid Alexandros Spyridonidis Friedrich Stölzel Rainer Ordemann Lutz P Müller Flore Sicre-de-Fontbrune Gabriele Ihorst Jürgen Kuball Jan E Ehlert Daniel Feger Eva-Maria Wagner Jean-Yves Cahn Jacqueline Schnell Florian Kuchenbauer Donald Bunjes Ronjon Chakraverty Simon Richardson Saar Gill Nicolaus Kröger Francis Ayuk Luca Vago Fabio Ciceri Antonia M Müller Takeshi Kondo Takanori Teshima Susan Klaeger Bernhard Kuster Dennis Dong Hwan Kim Daniel Weisdorf Walter van der Velden Daniela Dörfel Wolfgang Bethge Inken Hilgendorf Andreas Hochhaus Geoffroy Andrieux Melanie Börries Hauke Busch John Magenau Pavan Reddy Myriam Labopin Joseph H Antin Andrea S Henden Geoffrey R Hill Glen A Kennedy Merav Bar Anita Sarma Donal McLornan Ghulam Mufti Betul Oran Katayoun Rezvani Omid Shah Robert S Negrin Arnon Nagler Marco Prinz Andreas Burchert Andreas Neubauer Dietrich Beelen Andreas Mackensen Nikolas von Bubnoff Wolfgang Herr Burkhard Becher Gerard Socié Michael A Caligiuri Eliana Ruggiero Chiara Bonini Georg Häcker Justus Duyster Jürgen Finke Erika Pearce Bruce R Blazar Robert Zeiser

Nat Med 2018 Apr;24(4):526

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http://dx.doi.org/10.1038/nm0418-526cDOI Listing
April 2018

Sorafenib promotes graft-versus-leukemia activity in mice and humans through IL-15 production in FLT3-ITD-mutant leukemia cells.

Authors:
Nimitha R Mathew Francis Baumgartner Lukas Braun David O'Sullivan Simone Thomas Miguel Waterhouse Tony A Müller Kathrin Hanke Sanaz Taromi Petya Apostolova Anna L Illert Wolfgang Melchinger Sandra Duquesne Annette Schmitt-Graeff Lena Osswald Kai-Li Yan Arnim Weber Sonia Tugues Sabine Spath Dietmar Pfeifer Marie Follo Rainer Claus Michael Lübbert Christoph Rummelt Hartmut Bertz Ralph Wäsch Johanna Haag Andrea Schmidts Michael Schultheiss Dominik Bettinger Robert Thimme Evelyn Ullrich Yakup Tanriver Giang Lam Vuong Renate Arnold Philipp Hemmati Dominik Wolf Markus Ditschkowski Cordula Jilg Konrad Wilhelm Christian Leiber Sabine Gerull Jörg Halter Claudia Lengerke Thomas Pabst Thomas Schroeder Guido Kobbe Wolf Rösler Soroush Doostkam Stephan Meckel Kathleen Stabla Stephan K Metzelder Sebastian Halbach Tilman Brummer Zehan Hu Joern Dengjel Björn Hackanson Christoph Schmid Udo Holtick Christof Scheid Alexandros Spyridonidis Friedrich Stölzel Rainer Ordemann Lutz P Müller Flore Sicre-de-Fontbrune Gabriele Ihorst Jürgen Kuball Jan E Ehlert Daniel Feger Eva-Maria Wagner Jean-Yves Cahn Jacqueline Schnell Florian Kuchenbauer Donald Bunjes Ronjon Chakraverty Simon Richardson Saar Gill Nicolaus Kröger Francis Ayuk Luca Vago Fabio Ciceri Antonia M Müller Takeshi Kondo Takanori Teshima Susan Klaeger Bernhard Kuster Dennis Dong Hwan Kim Daniel Weisdorf Walter van der Velden Daniela Dörfel Wolfgang Bethge Inken Hilgendorf Andreas Hochhaus Geoffroy Andrieux Melanie Börries Hauke Busch John Magenau Pavan Reddy Myriam Labopin Joseph H Antin Andrea S Henden Geoffrey R Hill Glen A Kennedy Merav Bar Anita Sarma Donal McLornan Ghulam Mufti Betul Oran Katayoun Rezvani Omid Shah Robert S Negrin Arnon Nagler Marco Prinz Andreas Burchert Andreas Neubauer Dietrich Beelen Andreas Mackensen Nikolas von Bubnoff Wolfgang Herr Burkhard Becher Gerard Socié Michael A Caligiuri Eliana Ruggiero Chiara Bonini Georg Häcker Justus Duyster Jürgen Finke Erika Pearce Bruce R Blazar Robert Zeiser

Nat Med 2018 03 12;24(3):282-291. Epub 2018 Feb 12.

Department of Hematology, Oncology and Stem Cell Transplantation, Faculty of Medicine, University Medical Center Freiburg, University of Freiburg, Freiburg, Germany.

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http://dx.doi.org/10.1038/nm.4484DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6029618PMC
March 2018

The oligodendrocyte lineage transcription factor 2 (OLIG2) is epigenetically regulated in acute myeloid leukemia.

Exp Hematol 2017 11 28;55:76-85.e3. Epub 2017 Jul 28.

Department of Hematology/Oncology and Stem Cell Transplantation, University Medical Center, Freiburg, Germany; Department of Hematology/Oncology, Medical Center Augsburg, Augsburg, Germany. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S0301472X173070
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http://dx.doi.org/10.1016/j.exphem.2017.07.009DOI Listing
November 2017

Immunotherapy in adult acute leukemia.

Leuk Res 2017 09 29;60:63-73. Epub 2017 Jun 29.

Division of Hematology, Oncology and Stem Cell Transplantation, Department of Internal Medicine, Faculty of Medicine, University of Freiburg Medical Centre, Freiburg, Germany.

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http://dx.doi.org/10.1016/j.leukres.2017.06.011DOI Listing
September 2017

Evaluating the impact of genetic and epigenetic aberrations on survival and response in acute myeloid leukemia patients receiving epigenetic therapy.

Ann Hematol 2017 Apr 5;96(4):559-565. Epub 2017 Jan 5.

Department of Hematology/Oncology and Stem Cell Transplantation, University Medical Center, Hugstetterstr. 55, 79106, Freiburg, Germany.

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http://dx.doi.org/10.1007/s00277-016-2912-7DOI Listing
April 2017

Innovative strategies for adverse karyotype acute myeloid leukemia.

Curr Opin Hematol 2017 03;24(2):89-98

aService and Central Laboratory of Hematology, CHUV, University Hospital of Lausanne, Lausanne, Switzerland bDivision of Hematology, Oncology and Stem Cell Transplantation, Department of Internal Medicine, Faculty of Medicine, University of Freiburg Medical Center cFaculty of Biology, University of Freiburg dDKTK, German Consortium for Translational Cancer Research, Freiburg, Germany.

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http://Insights.ovid.com/crossref?an=00062752-201703000-0000
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http://dx.doi.org/10.1097/MOH.0000000000000318DOI Listing
March 2017

Improved Outcomes With Retinoic Acid and Arsenic Trioxide Compared With Retinoic Acid and Chemotherapy in Non-High-Risk Acute Promyelocytic Leukemia: Final Results of the Randomized Italian-German APL0406 Trial.

J Clin Oncol 2017 Feb 31;35(6):605-612. Epub 2016 Oct 31.

Uwe Platzbecker, Christian Thiede, Christoph Röllig, and Gerhard Ehninger, Universitätsklinikum Carl Gustav Carus der Technischen Universität Dresden; Uwe Platzbecker and Gerhard Ehninger, Study Alliance Leukemia, Dresden; Walter Fiedler, University Hospital Hamburg-Eppendorf; Norbert Schmitz, Asklepios Klinik St Georg Hamburg, Hamburg; Peter Brossart, Innere Medizin mit deSchwerpunkten Onkologie, Haematollogie un Rheumatologie, Bonn; Bernd Hertenstein, Klinikum Bremen Mitte, Bremen; Helmut R. Salih, University Hospital Tubingen; Mohammed Wattad, Kliniken Essen Süd, Essen; Michael Lübbert, University Medical Center, Freiburg; Christian H. Brandts, Goethe University Frankfurt, Frankfurt; Mathias Hänel, Klinikum Chemnitz gGmbH, Chemnitz; Hartmut Link, Klinik für Innere Medizin I, Westpfalz-Klinikum, Kaiserslautern; Konstanze Döhner, Hartmut Döhner, and Richard F. Schlenk, University Hospital Ulm, Ulm; Arnold Ganser, Hannover Medical School, Hannover, Germany; Giuseppe Avvisati, University Campus Bio-Medico; Laura Cicconi, Mariadomenica Divona, Sergio Amadori, and Francesco Lo-Coco, University Tor Vergata; Francesca Paoloni, Marco Vignetti, Fabio Efficace, Paola Fazi, and Franco Mandelli, Gruppo Italiano Malattie Ematologiche dell'Adulto Central Office; Marco Vignetti and Massimo Breccia, Sapienza University, Rome; Felicetto Ferrara, Cardarelli Hospital, Naples; Francesco Albano, University of Bari, Bari; Marco Sborgia, U.O. di Ematologia Clinica, Pescara; Eros Di Bona, San Bortolo Hospital, Vicenza; Erika Borlenghi, U.O. di Ematologia, Spedali Civili, Brescia; Roberto Cairoli, Ospedale Niguarda, Ca' Granda, SC Ematologia; Agostino Cortelezzi, Foundation Istituto di Ricovero e Cura a Carattere Scientifico Ca' Granda Ospedale Maggiore Policlinico and University of Milan, Milano; Alessandro Rambaldi, Azienda Opsedaliera Papa Giovanni XXIII, Bergamo; Lorella Melillo, Casa Sollievo della Sofferenza Hospital, IRCCS, San Giovanni Rotondo; Giorgio La Nasa, Centro Trapianti Midollo Osseo, Ospedale R. Binaghi, Università di Cagliari, Cagliari; Chiara Frairia, Hematology, Città della Salute e della Scienza, Torino; Enrico Maria Pogliani, Ospedale San Gerardo, Università degli Studi Milano Bicocca, Monza; Claudio Fozza, University of Sassari, Sassari; Alfonso Maria D'Arco, U.O. Medicina Interna e Onco-Ematologica P.O. "Umberto I," Nocera Inferiore, Nocera Inferiore; Nicola Di Renzo, Ospedale Vito Fazzi, Lecce; and Francesco Fabbiano, Ospedali Riuniti Villa Sofia-Cervello, Palermo, Italy.

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http://dx.doi.org/10.1200/JCO.2016.67.1982DOI Listing
February 2017

Elevated fetal haemoglobin is a predictor of better outcome in MDS/AML patients receiving 5-aza-2'-deoxycytidine (Decitabine).

Br J Haematol 2017 02 1;176(4):609-617. Epub 2016 Dec 1.

Division of Haematology, Oncology and Stem Cell Transplantation, Faculty of Medicine, University of Freiburg, Freiburg, Germany.

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http://dx.doi.org/10.1111/bjh.14463DOI Listing
February 2017

Targeting histone methyltransferases and demethylases in clinical trials for cancer therapy.

Clin Epigenetics 2016 24;8:57. Epub 2016 May 24.

Institute of Pharmaceutical Sciences, Albert-Ludwigs-University Freiburg, Albertstraße 25, 79104 Freiburg, Germany ; German Cancer Consortium (DKTK), Freiburg, Germany.

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http://dx.doi.org/10.1186/s13148-016-0223-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4877953PMC
December 2016

Epigenetic therapy approaches in non-small cell lung cancer: Update and perspectives.

Epigenetics 2016 Dec 15;11(12):858-870. Epub 2016 Nov 15.

a Division of Hematology, Oncology and Stem Cell Transplantation , University of Freiburg, Medical Center , Freiburg , Germany.

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https://www.tandfonline.com/doi/full/10.1080/15592294.2016.1
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http://dx.doi.org/10.1080/15592294.2016.1237345DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5193491PMC
December 2016

Epigenetic priming of non-small cell lung cancer cell lines to the antiproliferative and differentiating effects of all-trans retinoic acid.

J Cancer Res Clin Oncol 2015 Dec 26;141(12):2171-80. Epub 2015 May 26.

Division of Hematology, Oncology and Stem Cell Transplantation, Department of Internal Medicine, University of Freiburg Medical Center, Hugstetter Str. 55, 79106, Freiburg, Germany.

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http://dx.doi.org/10.1007/s00432-015-1987-1DOI Listing
December 2015

ZEB1-associated drug resistance in cancer cells is reversed by the class I HDAC inhibitor mocetinostat.

EMBO Mol Med 2015 Jun;7(6):831-47

Experimental Medicine I, Nikolaus-Fiebiger-Center for Molecular Medicine, FAU University Erlangen-Nürnberg, Erlangen, Germany German Cancer Consortium (DKTK), Freiburg and German Cancer Research Center (DKFZ), Heidelberg, Germany

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http://dx.doi.org/10.15252/emmm.201404396DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4459821PMC
June 2015

Therapeutic polo-like kinase 1 inhibition results in mitotic arrest and subsequent cell death of blasts in the bone marrow of AML patients and has similar effects in non-neoplastic cell lines.

Leuk Res 2015 Apr 28;39(4):462-70. Epub 2015 Jan 28.

Institute of Clinical Pathology, Department of Pathology, University Medical Center, Breisacher Str. 115a, 79106 Freiburg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.leukres.2015.01.007DOI Listing
April 2015

Combining DNA methyltransferase and histone deacetylase inhibition to treat acute myeloid leukemia/myelodysplastic syndrome: achievements and challenges.

Cancer 2015 Feb 21;121(4):498-501. Epub 2014 Oct 21.

Division of Hematology-Oncology, University of Freiburg Medical Center, Freiburg, Germany.

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http://doi.wiley.com/10.1002/cncr.29083
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http://dx.doi.org/10.1002/cncr.29083DOI Listing
February 2015

Clinical Results of Hypomethylating Agents in AML Treatment.

J Clin Med 2014 Dec 25;4(1):1-17. Epub 2014 Dec 25.

Department of Hematology, Radboud University Medical Center, PO Box 9191, 6500 HB Nijmegen, The Netherlands.

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http://dx.doi.org/10.3390/jcm4010001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4470235PMC
December 2014

Quantitative determination of decitabine incorporation into DNA and its effect on mutation rates in human cancer cells.

Nucleic Acids Res 2014 Oct 26;42(19):e152. Epub 2014 Aug 26.

Division of Epigenetics, DKFZ-ZMBH Alliance, German Cancer Research Center, 69120 Heidelberg, Germany

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http://dx.doi.org/10.1093/nar/gku775DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4231731PMC
October 2014

Successful vemurafenib salvage treatment in a patient with primary refractory hairy cell leukemia and pulmonary aspergillosis.

Ann Hematol 2014 Aug 14;93(8):1439-40. Epub 2013 Dec 14.

Department of Hematology and Oncology, University of Freiburg Medical Center, Hugstetter Straße 55, 79106, Freiburg, Germany,

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http://dx.doi.org/10.1007/s00277-013-1987-7DOI Listing
August 2014

ID2 and ID3 protein expression mirrors granulopoietic maturation and discriminates between acute leukemia subtypes.

Histochem Cell Biol 2014 Apr 30;141(4):431-40. Epub 2013 Nov 30.

Department of Pathology, University Medical Center, Breisacher Str. 115a, 79106, Freiburg, Germany.

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http://link.springer.com/10.1007/s00418-013-1169-7
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http://dx.doi.org/10.1007/s00418-013-1169-7DOI Listing
April 2014

The AML1/ETO target gene LAT2 interferes with differentiation of normal hematopoietic precursor cells.

Leuk Res 2014 Mar 25;38(3):340-5. Epub 2013 Dec 25.

Department of Hematology and Oncology, University of Freiburg, Medical Center, Freiburg, Germany.

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http://dx.doi.org/10.1016/j.leukres.2013.12.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4135084PMC
March 2014

No difference between posaconazole and fluconazole antifungal prophylaxis and mycological diagnostics except costs in patients undergoing AML chemotherapy: a 1-year "real-life" evaluation.

Ann Hematol 2014 Jan 15;93(1):165-7. Epub 2013 Aug 15.

Division of Hematology, Oncology and Stem Cell Transplantation, University Clinic Department of Internal Medicine I, 79106, Freiburg, Germany,

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http://dx.doi.org/10.1007/s00277-013-1854-6DOI Listing
January 2014

Sequential combination of gemtuzumab ozogamicin and standard chemotherapy in older patients with newly diagnosed acute myeloid leukemia: results of a randomized phase III trial by the EORTC and GIMEMA consortium (AML-17).

J Clin Oncol 2013 Dec 14;31(35):4424-30. Epub 2013 Oct 14.

Sergio Amadori and Adriano Venditti, Tor Vergata University Hospital; Paolo De Fabritiis, St Eugenio Hospital; Roberto Latagliata, University Sapienza; Paola Fazi and Marco Vignetti, Gruppo Italiano Malattie Ematologiche dell'Adulto, Roma; Franca Falzetti, University Hospital, Perugia; Domenico Magro, Pugliese Hospital, Catanzaro; Giorgina Specchia, University Hospital, Bari, Italy; Stefan Suciu and Matthias Karrasch, European Organisation for Research and Treatment of Cancer, Brussels; Dominik Selleslag, Algemeen Ziekenhuis St Jan, Brugge; Zwi Berneman, University Hospital, Antwerp, Belgium; Roberto Stasi, St George's Hospital, London, United Kingdom; Helmut R. Salih, University Hospital, Tubingen; Anthony D. Ho, University Hospital, Heidelberg; Michael Lübbert, Albert Ludwigs University, Freiburg, Germany; Petra Muus and Theo de Witte, Radboud University Medical Centre, Nijmegen; Constantijn J.M. Halkes and Roel Willemze, University Medical Center, Leiden, the Netherlands; Xavier Thomas, Edouard Herriot Hospital, Lyon; Jean-Pierre Marie, St. Antoine Hospital, Paris, France; and José E. Guimaraes, University Hospital, Porto, Portugal.

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http://dx.doi.org/10.1200/JCO.2013.49.0771DOI Listing
December 2013

Prognostic significance of expression levels of stem cell regulators MSI2 and NUMB in acute myeloid leukemia.

Ann Hematol 2013 Mar 12;92(3):315-23. Epub 2012 Dec 12.

Department of Hematology, Hemostasis, Oncology, and Stem Cell Transplantation, Hannover Medical School, Carl-Neuberg Str. 1, 30625, Hannover, Germany.

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http://dx.doi.org/10.1007/s00277-012-1637-5DOI Listing
March 2013

Decitabine induces very early in vivo DNA methylation changes in blasts from patients with acute myeloid leukemia.

Leuk Res 2013 Feb 15;37(2):190-6. Epub 2012 Nov 15.

Division Epigenomics and Cancer Risk Factors, German Cancer Research Center, Heidelberg, Germany.

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http://dx.doi.org/10.1016/j.leukres.2012.10.015DOI Listing
February 2013

MeDIP coupled with a promoter tiling array as a platform to investigate global DNA methylation patterns in AML cells.

Leuk Res 2013 Jan 11;37(1):102-11. Epub 2012 Oct 11.

Division of Hematology/Oncology, Department of Medicine, University Medical Center Freiburg, Germany.

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http://dx.doi.org/10.1016/j.leukres.2012.09.014DOI Listing
January 2013

Clinical results with the DNA hypomethylating agent 5-aza-2'-deoxycytidine (decitabine) in patients with myelodysplastic syndromes: an update.

Semin Hematol 2012 Oct;49(4):330-41

Department of Hematology/Oncology, University of Freiburg Medical Center, Freiburg, Germany.

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http://dx.doi.org/10.1053/j.seminhematol.2012.08.001DOI Listing
October 2012

HDAC6 as a target for antileukemic drugs in acute myeloid leukemia.

Leuk Res 2012 Aug 29;36(8):1055-62. Epub 2012 Mar 29.

Department of Hematology/Oncology, University of Freiburg Medical Center, Freiburg, Germany.

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http://dx.doi.org/10.1016/j.leukres.2012.02.026DOI Listing
August 2012

Immune response as a possible mechanism of long-lasting disease control in spontaneous remission of MLL/AF9-positive acute myeloid leukemia.

Ann Hematol 2012 Jan 29;91(1):27-32. Epub 2011 Sep 29.

Department of Hematology and Oncology, University of Freiburg Medical Center, Hugstetter Straße 55, 79106 Freiburg, Germany.

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http://dx.doi.org/10.1007/s00277-011-1332-yDOI Listing
January 2012

Regulation of the adaptor molecule LAT2, an in vivo target gene of AML1/ETO (RUNX1/RUNX1T1), during myeloid differentiation.

Br J Haematol 2011 Jun 13;153(5):612-22. Epub 2011 Apr 13.

Department of Haematology/Oncology, University of Freiburg, Hugstetter Strasse 55, Freiburg, Germany.

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http://doi.wiley.com/10.1111/j.1365-2141.2011.08586.x
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http://dx.doi.org/10.1111/j.1365-2141.2011.08586.xDOI Listing
June 2011