Michael L Shelanski

Michael L Shelanski

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Michael L Shelanski

Michael L Shelanski

Publications by authors named "Michael L Shelanski"

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21Publications

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Activating Transcription Factor 4 (ATF4) Regulates Neuronal Activity by Controlling GABAR Trafficking.

J Neurosci 2018 Jul 6;38(27):6102-6113. Epub 2018 Jun 6.

Department of Pathology & Cell Biology and the Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University Medical Center, New York, New York 10033

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http://dx.doi.org/10.1523/JNEUROSCI.3350-17.2018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6596153PMC
July 2018

Brain-Derived Neurotrophic Factor Elevates Activating Transcription Factor 4 (ATF4) in Neurons and Promotes ATF4-Dependent Induction of .

Front Mol Neurosci 2018 1;11:62. Epub 2018 Mar 1.

Department of Pathology and Cell Biology, Columbia University College of Physicians and Surgeons, New York, NY, United States.

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http://dx.doi.org/10.3389/fnmol.2018.00062DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5863619PMC
March 2018

Post-translational remodeling of ryanodine receptor induces calcium leak leading to Alzheimer's disease-like pathologies and cognitive deficits.

Acta Neuropathol 2017 11 19;134(5):749-767. Epub 2017 Jun 19.

Department of Physiology and Cellular Biophysics, Clyde and Helen Wu Center for Molecular Cardiology, Columbia University College of Physicians and Surgeons, New York, NY, 10032, USA.

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http://dx.doi.org/10.1007/s00401-017-1733-7DOI Listing
November 2017

Stabilization of dynamic microtubules by mDia1 drives Tau-dependent Aβ synaptotoxicity.

J Cell Biol 2017 10 6;216(10):3161-3178. Epub 2017 Sep 6.

Department of Pathology, Anatomy and Cell Biology, Columbia University, New York, NY

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http://dx.doi.org/10.1083/jcb.201701045DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5626542PMC
October 2017

Caspase-2 and tau-a toxic partnership?

Nat Med 2016 11;22(11):1207-1208

Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Department of Pathology and Cell Biology, Columbia University, New York, New York, USA.

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http://dx.doi.org/10.1038/nm.4227DOI Listing
November 2016

Assembly and interrogation of Alzheimer's disease genetic networks reveal novel regulators of progression.

PLoS One 2015 17;10(3):e0120352. Epub 2015 Mar 17.

Taub Institute for Research on Alzheimer's Disease & the Aging Brain and the Department of Pathology & Cell Biology, Columbia University, New York, NY, 10032, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0120352PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4363671PMC
February 2016

Functional role of RNA polymerase II and P70 S6 kinase in KCl withdrawal-induced cerebellar granule neuron apoptosis.

J Biol Chem 2015 Feb 7;290(9):5267-79. Epub 2015 Jan 7.

the Department of Pathology and Cell Biology, Taub Center for Alzheimer's Disease, College of Physicians and Surgeons, Columbia University, New York, New York 10032.

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http://dx.doi.org/10.1074/jbc.M114.575225DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4342447PMC
February 2015

Activating transcription factor 4 (ATF4) modulates post-synaptic development and dendritic spine morphology.

Front Cell Neurosci 2014 30;8:177. Epub 2014 Jun 30.

Department of Pathology and Cell Biology, Columbia University Medical Center New York, NY, USA.

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http://dx.doi.org/10.3389/fncel.2014.00177DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4075335PMC
July 2014

Novel late-onset Alzheimer disease loci variants associate with brain gene expression.

Authors:
Mariet Allen Fanggeng Zou High Seng Chai Curtis S Younkin Julia Crook V Shane Pankratz Minerva M Carrasquillo Christopher N Rowley Asha A Nair Sumit Middha Sooraj Maharjan Thuy Nguyen Li Ma Kimberly G Malphrus Ryan Palusak Sarah Lincoln Gina Bisceglio Constantin Georgescu Debra Schultz Fariborz Rakhshan Christopher P Kolbert Jin Jen Jonathan L Haines Richard Mayeux Margaret A Pericak-Vance Lindsay A Farrer Gerard D Schellenberg Ronald C Petersen Neill R Graff-Radford Dennis W Dickson Steven G Younkin Nilüfer Ertekin-Taner Liana G Apostolova Steven E Arnold Clinton T Baldwin Robert Barber Michael M Barmada Thomas Beach Gary W Beecham Duane Beekly David A Bennett Eileen H Bigio Thomas D Bird Deborah Blacker Bradley F Boeve James D Bowen Adam Boxer James R Burke Jacqueline Buros Joseph D Buxbaum Nigel J Cairns Laura B Cantwell Chuanhai Cao Chris S Carlson Regina M Carney Steven L Carroll Helena C Chui David G Clark Jason Corneveaux Carl W Cotman Paul K Crane Carlos Cruchaga Jeffrey L Cummings Philip L De Jager Charles DeCarli Steven T DeKosky F Yesim Demirci Ramon Diaz-Arrastia Malcolm Dick Beth A Dombroski Ranjan Duara William D Ellis Denis Evans Kelley M Faber Kenneth B Fallon Martin R Farlow Steven Ferris Tatiana M Foroud Matthew Frosch Douglas R Galasko Paul J Gallins Mary Ganguli Marla Gearing Daniel H Geschwind Bernardino Ghetti John R Gilbert Sid Gilman Bruno Giordani Jonathan D Glass Alison M Goate Robert C Green John H Growdon Hakon Hakonarson Ronald L Hamilton John Hardy Lindy E Harrell Elizabeth Head Lawrence S Honig Matthew J Huentelman Christine M Hulette Bradley T Hyman Gail P Jarvik Gregory A Jicha Lee-Way Jin Gyungah Jun M Ilyas Kamboh Jason Karlawish Anna Karydas John S K Kauwe Jeffrey A Kaye Nancy Kennedy Ronald Kim Edward H Koo Neil W Kowall Patricia Kramer Walter A Kukull James J Lah Eric B Larson Allan I Levey Andrew P Lieberman Oscar L Lopez Kathryn L Lunetta Wendy J Mack Daniel C Marson Eden R Martin Frank Martiniuk Deborah C Mash Eliezer Masliah Wayne C McCormick Susan M McCurry Andrew N McDavid Ann C McKee Marsel Mesulam Bruce L Miller Carol A Miller Joshua W Miller Thomas J Montine John C Morris Amanda J Myers Adam C Naj Petra Nowotny Joseph E Parisi Daniel P Perl Elaine Peskind Wayne W Poon Huntington Potter Joseph F Quinn Ashok Raj Ruchita A Rajbhandary Murray Raskind Eric M Reiman Barry Reisberg Christiane Reitz John M Ringman Erik D Roberson Ekaterina Rogaeva Roger N Rosenberg Mary Sano Andrew J Saykin Julie A Schneider Lon S Schneider William Seeley Michael L Shelanski Michael A Slifer Charles D Smith Joshua A Sonnen Salvatore Spina Peter St George-Hyslop Robert A Stern Rudolph E Tanzi John Q Trojanowski Juan C Troncoso Debby W Tsuang Vivianna M Van Deerlin Badri Narayan Vardarajan Harry V Vinters Jean Paul Vonsattel Li-San Wang Sandra Weintraub Kathleen A Welsh-Bohmer Jennifer Williamson Randall L Woltjer

Neurology 2012 Jul 20;79(3):221-8. Epub 2012 Jun 20.

Department of Neuroscience, Biostatistics Unit, Mayo Clinic Florida, Jacksonville, FL, USA.

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http://dx.doi.org/10.1212/WNL.0b013e3182605801DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3398432PMC
July 2012

Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease.

Authors:
Adam C Naj Gyungah Jun Gary W Beecham Li-San Wang Badri Narayan Vardarajan Jacqueline Buros Paul J Gallins Joseph D Buxbaum Gail P Jarvik Paul K Crane Eric B Larson Thomas D Bird Bradley F Boeve Neill R Graff-Radford Philip L De Jager Denis Evans Julie A Schneider Minerva M Carrasquillo Nilufer Ertekin-Taner Steven G Younkin Carlos Cruchaga John S K Kauwe Petra Nowotny Patricia Kramer John Hardy Matthew J Huentelman Amanda J Myers Michael M Barmada F Yesim Demirci Clinton T Baldwin Robert C Green Ekaterina Rogaeva Peter St George-Hyslop Steven E Arnold Robert Barber Thomas Beach Eileen H Bigio James D Bowen Adam Boxer James R Burke Nigel J Cairns Chris S Carlson Regina M Carney Steven L Carroll Helena C Chui David G Clark Jason Corneveaux Carl W Cotman Jeffrey L Cummings Charles DeCarli Steven T DeKosky Ramon Diaz-Arrastia Malcolm Dick Dennis W Dickson William G Ellis Kelley M Faber Kenneth B Fallon Martin R Farlow Steven Ferris Matthew P Frosch Douglas R Galasko Mary Ganguli Marla Gearing Daniel H Geschwind Bernardino Ghetti John R Gilbert Sid Gilman Bruno Giordani Jonathan D Glass John H Growdon Ronald L Hamilton Lindy E Harrell Elizabeth Head Lawrence S Honig Christine M Hulette Bradley T Hyman Gregory A Jicha Lee-Way Jin Nancy Johnson Jason Karlawish Anna Karydas Jeffrey A Kaye Ronald Kim Edward H Koo Neil W Kowall James J Lah Allan I Levey Andrew P Lieberman Oscar L Lopez Wendy J Mack Daniel C Marson Frank Martiniuk Deborah C Mash Eliezer Masliah Wayne C McCormick Susan M McCurry Andrew N McDavid Ann C McKee Marsel Mesulam Bruce L Miller Carol A Miller Joshua W Miller Joseph E Parisi Daniel P Perl Elaine Peskind Ronald C Petersen Wayne W Poon Joseph F Quinn Ruchita A Rajbhandary Murray Raskind Barry Reisberg John M Ringman Erik D Roberson Roger N Rosenberg Mary Sano Lon S Schneider William Seeley Michael L Shelanski Michael A Slifer Charles D Smith Joshua A Sonnen Salvatore Spina Robert A Stern Rudolph E Tanzi John Q Trojanowski Juan C Troncoso Vivianna M Van Deerlin Harry V Vinters Jean Paul Vonsattel Sandra Weintraub Kathleen A Welsh-Bohmer Jennifer Williamson Randall L Woltjer Laura B Cantwell Beth A Dombroski Duane Beekly Kathryn L Lunetta Eden R Martin M Ilyas Kamboh Andrew J Saykin Eric M Reiman David A Bennett John C Morris Thomas J Montine Alison M Goate Deborah Blacker Debby W Tsuang Hakon Hakonarson Walter A Kukull Tatiana M Foroud Jonathan L Haines Richard Mayeux Margaret A Pericak-Vance Lindsay A Farrer Gerard D Schellenberg

Nat Genet 2011 May 3;43(5):436-41. Epub 2011 Apr 3.

The John P. Hussman Institute for Human Genomics, University of Miami, Miami, Florida, USA.

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http://dx.doi.org/10.1038/ng.801DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3090745PMC
May 2011

RTP801/REDD1 regulates the timing of cortical neurogenesis and neuron migration.

J Neurosci 2011 Mar;31(9):3186-96

Department of Pathology and Cell Biology, Columbia University College of Physicians and Surgeons, New York, New York 10032, USA.

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http://dx.doi.org/10.1523/JNEUROSCI.4011-10.2011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3089438PMC
March 2011

Increased neurogenesis in young transgenic mice overexpressing human APP(Sw, Ind).

J Alzheimers Dis 2007 Nov;12(3):229-40

Taub Institute for Research on Alzheimer's disease and the Aging Brain and Department of Pathology, Columbia University, New York, NY 10032, USA.

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November 2007

Cell cycle inhibition and retinoblastoma protein overexpression prevent Purkinje cell death in organotypic slice cultures.

Dev Neurobiol 2007 May;67(6):818-26

Department of Pathology, Taub Center for the Study of Alzheimer's Disease and Aging Brain, College of Physicians and Surgeons, Columbia University, New York, New York 10032, USA. 10032

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http://dx.doi.org/10.1002/dneu.20394DOI Listing
May 2007

Highly efficient small interfering RNA delivery to primary mammalian neurons induces MicroRNA-like effects before mRNA degradation.

J Neurosci 2004 Nov;24(45):10040-6

Department of Pathology, Taub Institute for the Study of Alzheimer's Disease and the Aging Brain, Columbia University College of Physicians and Surgeons, New York, New York 10032, USA.

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http://dx.doi.org/10.1523/JNEUROSCI.3643-04.2004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6730191PMC
November 2004

Divergence of the apoptotic pathways induced by 4-hydroxynonenal and amyloid beta-protein.

Neurobiol Aging 2004 Sep;25(8):1057-66

Department of Pathology, Columbia University College of Physicians and Surgeons, 630 W. 168th Street, New York, NY 10032, USA.

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http://dx.doi.org/10.1016/j.neurobiolaging.2003.10.003DOI Listing
September 2004

Neurogenic effect of beta-amyloid peptide in the development of neural stem cells.

J Neurosci 2004 Jun;24(23):5439-44

Taub Institute for Research on Alzheimer's Disease and the Aging Brain and Department of Pathology, Columbia University, New York, New York 10032, USA.

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http://dx.doi.org/10.1523/JNEUROSCI.0974-04.2004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6729298PMC
June 2004

Dendrite and dendritic spine alterations in Alzheimer models.

J Neurocytol 2004 May;33(3):377-87

Taub Institute for Research on Alzheimer's Disease and the Aging Brain and Department of Pathology, Columbia University, New York, NY 10032, USA.

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http://dx.doi.org/10.1023/B:NEUR.0000044197.83514.64DOI Listing
May 2004