Publications by authors named "Michael L Klein"

100Publications

From Examining the Relationship between (Corona)Viral Adhesins and Galectins to Glyco-Perspectives.

Biophys J 2020 Nov 25. Epub 2020 Nov 25.

Institute of Physiological Chemistry, Faculty of Veterinary Medicine, Ludwig-Maximilians-University Munich, Veterinärstr. 13, 80539 Munich, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.bpj.2020.11.020DOI Listing
November 2020

Unraveling topology-induced shape transformations in dendrimersomes.

Soft Matter 2020 Aug 13. Epub 2020 Aug 13.

DWI-Leibniz Institute for Interactive Materials, Forckenbeckstraße 50, 52074 Aachen, Germany.

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http://dx.doi.org/10.1039/d0sm01097aDOI Listing
August 2020

Property Decoupling across the Embryonic Nucleus-Melt Interface during Polymer Crystal Nucleation.

J Phys Chem B 2020 Jun 2;124(23):4793-4804. Epub 2020 Jun 2.

Department of Chemistry, Temple University, Philadelphia, Pennsylvania 19122, United States.

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http://dx.doi.org/10.1021/acs.jpcb.0c01972DOI Listing
June 2020

Direct Visualization of Vesicle Disassembly and Reassembly Using Photocleavable Dendrimers Elucidates Cargo Release Mechanisms.

ACS Nano 2020 06 18;14(6):7398-7411. Epub 2020 May 18.

Department of Cell and Developmental Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104-6058, United States.

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http://dx.doi.org/10.1021/acsnano.0c02912DOI Listing
June 2020

Molecular Simulation of Covalent Bond Dynamics in Liquid Silicon.

J Phys Chem B 2020 04 8;124(15):3180-3185. Epub 2020 Apr 8.

Institute for Computational Molecular Science and Department of Chemistry, Temple University, Philadelphia, Pennsylvania 19122, United States.

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http://dx.doi.org/10.1021/acs.jpcb.0c01798DOI Listing
April 2020

Lone Pair Rotational Dynamics in Solids.

Phys Rev Lett 2020 Feb;124(6):066001

Institute for Computational Molecular Science and Department of Chemistry, Temple University, Philadelphia, Pennsylvania 19122, USA.

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http://dx.doi.org/10.1103/PhysRevLett.124.066001DOI Listing
February 2020

Coexistence of Lipid Phases Stabilizes Interstitial Water in the Outer Layer of Mammalian Skin.

Biophys J 2020 04 12;118(7):1588-1601. Epub 2020 Feb 12.

Institute for Computational Molecular Science and Temple Materials Institute, Philadelphia, Pennsylvania. Electronic address:

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http://dx.doi.org/10.1016/j.bpj.2020.01.044DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7136285PMC
April 2020

Reply.

Ophthalmology 2020 03;127(3):e19-e20

Division of Epidemiology and Clinical Applications, National Eye Institute, National Institutes of Health, Bethesda, Maryland. Electronic address:

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http://dx.doi.org/10.1016/j.ophtha.2019.10.033DOI Listing
March 2020

Monodisperse Polymer Melts Crystallize via Structurally Polydisperse Nanoscale Clusters: Insights from Polyethylene.

Polymers (Basel) 2020 Feb 14;12(2). Epub 2020 Feb 14.

Department of Materials Chemistry, Nagoya University, Furo-cho, Chikusa-ku, Nagoya 464-8603, Japan.

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http://dx.doi.org/10.3390/polym12020447DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7077701PMC
February 2020

Aqueous solvation of the chloride ion revisited with density functional theory: impact of correlation and exchange approximations.

Phys Chem Chem Phys 2020 May 4;22(19):10666-10675. Epub 2020 Feb 4.

Institute for Computational Molecular Science, Temple University SERC, Philadelphia, 1925, N 12th St, PA 19122, USA.

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http://dx.doi.org/10.1039/c9cp06821jDOI Listing
May 2020

Incidence of Macular Atrophy after Untreated Neovascular Age-Related Macular Degeneration: Age-Related Eye Disease Study Report 40.

Ophthalmology 2020 06 26;127(6):784-792. Epub 2019 Nov 26.

Division of Epidemiology and Clinical Applications, National Eye Institute, National Institutes of Health, Bethesda, Maryland. Electronic address:

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http://dx.doi.org/10.1016/j.ophtha.2019.11.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7246151PMC
June 2020

First-Principles Calculation of Water p Using the Newly Developed SCAN Functional.

J Phys Chem Lett 2020 Jan 13;11(1):54-59. Epub 2019 Dec 13.

Department of Chemistry , Temple University , Philadelphia , Pennsylvania 19122 , United States.

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http://dx.doi.org/10.1021/acs.jpclett.9b02913DOI Listing
January 2020

Suppression of Zika Virus Infection in the Brain by the Antiretroviral Drug Rilpivirine.

Mol Ther 2019 12 11;27(12):2067-2079. Epub 2019 Oct 11.

Department of Neuroscience, Center for Neurovirology, Lewis Katz School of Medicine at Temple University, 3500 N. Broad Street, Philadelphia, PA 19140, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ymthe.2019.10.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6904669PMC
December 2019

Divining the shape of nascent polymer crystal nuclei.

J Chem Phys 2019 Oct;151(14):144901

Department of Materials Chemistry, Nagoya University, Furo-cho, Chikusa-ku, Nagoya 464-8603, Japan.

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http://dx.doi.org/10.1063/1.5123983DOI Listing
October 2019

Defect-enriched tunability of electronic and charge-carrier transport characteristics of 2D borocarbonitride (BCN) monolayers from ab initio calculations.

Nanoscale 2019 Nov 5;11(41):19398-19407. Epub 2019 Aug 5.

International Center for Materials Science, Jawaharlal Nehru Centre for Advanced Scientific Research, P.O Jakkur, Bangalore 560064, India.

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http://dx.doi.org/10.1039/c9nr04096jDOI Listing
November 2019

Membrane-Mimetic Dendrimersomes Engulf Living Bacteria via Endocytosis.

Nano Lett 2019 08 18;19(8):5732-5738. Epub 2019 Jul 18.

DWI-Leibniz Institute for Interactive Materials , Forckenbeckstraße 50 , 52074 Aachen , Germany.

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http://dx.doi.org/10.1021/acs.nanolett.9b02349DOI Listing
August 2019

Halogen Bond Structure and Dynamics from Molecular Simulations.

J Phys Chem B 2019 07 16;123(29):6266-6273. Epub 2019 Jul 16.

Institute for Computational Molecular Science and Department of Chemistry , Temple University , Philadelphia , Pennsylvania 19122 , United States.

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http://dx.doi.org/10.1021/acs.jpcb.9b04820DOI Listing
July 2019

A coarse-grain model for entangled polyethylene melts and polyethylene crystallization.

J Chem Phys 2019 Jun;150(24):244901

Department of Materials Chemistry, Nagoya University, Furo-cho, Chikusa-ku, Nagoya 464-8603, Japan.

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http://dx.doi.org/10.1063/1.5092229DOI Listing
June 2019

Toward a Model for Activation of Orai Channel.

iScience 2019 Jun 1;16:356-367. Epub 2019 Jun 1.

Institute for Computational Molecular Science, Temple University, Philadelphia, PA 19122, USA. Electronic address:

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http://dx.doi.org/10.1016/j.isci.2019.05.041DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6579751PMC
June 2019

Bond-Dependent Thole Model for Polarizability and Spectroscopy.

J Phys Chem A 2019 Jun 13;123(25):5378-5387. Epub 2019 Jun 13.

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http://dx.doi.org/10.1021/acs.jpca.8b12011DOI Listing
June 2019

Polymer nucleation under high-driving force, long-chain conditions: Heat release and the separation of time scales.

J Chem Phys 2019 Mar;150(11):114901

Department of Chemistry, Temple University, Philadelphia, Pennsylvania 19122, USA.

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http://dx.doi.org/10.1063/1.5084773DOI Listing
March 2019

Exponential Scaling of Water Exchange Rates with Ion Interaction Strength from the Perspective of Dynamic Facilitation Theory.

J Phys Chem A 2019 Feb 23;123(5):1077-1084. Epub 2019 Jan 23.

Institute for Computational Molecular Science and Department of Chemistry , Temple University , Philadelphia , Pennsylvania 19122 , United States.

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http://dx.doi.org/10.1021/acs.jpca.8b09667DOI Listing
February 2019

Bioactive cell-like hybrids from dendrimersomes with a human cell membrane and its components.

Proc Natl Acad Sci U S A 2019 01 27;116(3):744-752. Epub 2018 Dec 27.

Roy & Diana Vagelos Laboratories, Department of Chemistry, University of Pennsylvania, Philadelphia, PA 19104-6323;

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http://dx.doi.org/10.1073/pnas.1811307116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6338876PMC
January 2019

Phonons and thermal conducting properties of borocarbonitride (BCN) nanosheets.

Nanoscale 2018 Dec 24;10(47):22148-22154. Epub 2018 Oct 24.

Institute for Computational Molecular Science (ICMS), Temple University, Philadelphia, PA 19122, USA.

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http://xlink.rsc.org/?DOI=C8NR07373B
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http://dx.doi.org/10.1039/c8nr07373bDOI Listing
December 2018

A hypothetical molecular mechanism for TRPV1 activation that invokes rotation of an S6 asparagine.

J Gen Physiol 2018 11 17;150(11):1554-1566. Epub 2018 Oct 17.

Institute for Computational Molecular Science, Temple University, Philadelphia, PA

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http://dx.doi.org/10.1085/jgp.201812124DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6219692PMC
November 2018

Electron-Hole Theory of the Effect of Quantum Nuclei on the X-Ray Absorption Spectra of Liquid Water.

Phys Rev Lett 2018 Sep;121(13):137401

Department of Physics, Temple University, Philadelphia, Pennsylvania 19122, USA.

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https://link.aps.org/doi/10.1103/PhysRevLett.121.137401
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http://dx.doi.org/10.1103/PhysRevLett.121.137401DOI Listing
September 2018

Mechanically Strong Polymer Sheets from Aligned Ultrahigh-Molecular-Weight Polyethylene Nanocomposites.

J Phys Chem Lett 2018 May 7;9(10):2652-2658. Epub 2018 May 7.

Department of Mechanical and Aerospace Engineering, Research and Education in Energy, Environment & Water (RENEW) Institute , University at Buffalo, The State University of New York , Buffalo , New York 14260 , United States.

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http://dx.doi.org/10.1021/acs.jpclett.8b00790DOI Listing
May 2018

Bioactivity-Guided Isolation of Potential Antidiabetic and Antihyperlipidemic Compounds from Trigonella stellata.

J Nat Prod 2018 05 20;81(5):1154-1161. Epub 2018 Apr 20.

National Center for Natural Products Research, School of Pharmacy , University of Mississippi , University , Mississippi 38677 , United States.

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http://pubs.acs.org/doi/10.1021/acs.jnatprod.7b00707
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http://dx.doi.org/10.1021/acs.jnatprod.7b00707DOI Listing
May 2018

Light-induced dilation in nanosheets of charge-transfer complexes.

Proc Natl Acad Sci U S A 2018 04 26;115(15):3776-3781. Epub 2018 Mar 26.

Department of Mechanical and Aerospace Engineering, University at Buffalo, The State University of New York, Buffalo, NY 14260;

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http://dx.doi.org/10.1073/pnas.1800234115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5899485PMC
April 2018

Hydroxide diffuses slower than hydronium in water because its solvated structure inhibits correlated proton transfer.

Nat Chem 2018 04 12;10(4):413-419. Epub 2018 Mar 12.

Department of Physics, Temple University, Philadelphia, PA, USA.

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http://dx.doi.org/10.1038/s41557-018-0010-2DOI Listing
April 2018

Intramolecular Hydrogen Bonding Appetency for Conformational Penchants in Oxalohydrazide Fluoro Derivatives: NMR, MD, QTAIM, and NCI Studies.

J Phys Chem A 2018 Mar 6;122(10):2703-2713. Epub 2018 Mar 6.

NMR Research Centre , Indian Institute of Science , Bangalore , Karnataka 560012 , India.

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http://dx.doi.org/10.1021/acs.jpca.8b00913DOI Listing
March 2018

Ion Channel Sensing: Are Fluctuations the Crux of the Matter?

J Phys Chem Lett 2018 Mar 27;9(6):1260-1264. Epub 2018 Feb 27.

Institute for Computational Molecular Science , Temple University , Philadelphia , Pennsylvania 19122 , United States.

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http://dx.doi.org/10.1021/acs.jpclett.7b03396DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6310152PMC
March 2018

Genome-wide analysis of disease progression in age-related macular degeneration.

Hum Mol Genet 2018 03;27(5):929-940

Division of Pulmonary Medicine, Allergy and Immunology, Department of Pediatrics, Children's Hospital of Pittsburgh of UPMC University of Pittsburgh, Pittsburgh, PA 15224, USA.

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http://dx.doi.org/10.1093/hmg/ddy002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6059197PMC
March 2018

Bioactive products from singlet oxygen photooxygenation of cannabinoids.

Eur J Med Chem 2018 Jan 21;143:983-996. Epub 2017 Nov 21.

ElSohly Laboratories, Inc., 5 Industrial Park Drive, Oxford, MS 38655, United States; Department of Pharmaceutics, University of Mississippi, University, MS 38677, United States.

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http://dx.doi.org/10.1016/j.ejmech.2017.11.043DOI Listing
January 2018

Chemical physics of water.

Proc Natl Acad Sci U S A 2017 12 11;114(51):13325-13326. Epub 2017 Dec 11.

Institute for Computational Molecular Science, Temple University, Philadelphia, PA 19122

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http://dx.doi.org/10.1073/pnas.1719350115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5754819PMC
December 2017

Author Correction: Tunable two-dimensional interfacial coupling in molecular heterostructures.

Nat Commun 2017 11 17;8(1):1699. Epub 2017 Nov 17.

Department of Mechanical Engineering, Temple University, Philadelphia, PA, 19122, USA.

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http://dx.doi.org/10.1038/s41467-017-01767-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5693927PMC
November 2017

Ab initio theory and modeling of water.

Proc Natl Acad Sci U S A 2017 10 25;114(41):10846-10851. Epub 2017 Sep 25.

Department of Physics, Temple University, Philadelphia, PA 19122;

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http://dx.doi.org/10.1073/pnas.1712499114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5642722PMC
October 2017

Reaction of a Programmable Glycan Presentation of Glycodendrimersomes and Cells with Engineered Human Lectins To Show the Sugar Functionality of the Cell Surface.

Angew Chem Int Ed Engl 2017 11 10;56(46):14677-14681. Epub 2017 Oct 10.

Roy & Diana Vagelos Laboratories, Department of Chemistry, University of Pennsylvania, Philadelphia, Pennsylvania, 19104-6323, USA.

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http://dx.doi.org/10.1002/anie.201708237DOI Listing
November 2017

Tunable two-dimensional interfacial coupling in molecular heterostructures.

Nat Commun 2017 08 22;8(1):312. Epub 2017 Aug 22.

Department of Mechanical Engineering, Temple University, Philadelphia, PA, 19122, USA.

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http://dx.doi.org/10.1038/s41467-017-00390-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5567094PMC
August 2017

Janus dendrimersomes coassembled from fluorinated, hydrogenated, and hybrid Janus dendrimers as models for cell fusion and fission.

Proc Natl Acad Sci U S A 2017 08 7;114(34):E7045-E7053. Epub 2017 Aug 7.

Roy & Diana Vagelos Laboratories, Department of Chemistry, University of Pennsylvania, Philadelphia, PA 19104-6323;

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http://dx.doi.org/10.1073/pnas.1708380114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5576825PMC
August 2017

CLINICOPATHOLOGIC CORRELATION OF RETINAL ANGIOMATOUS PROLIFERATION TREATED WITH RANIBIZUMAB.

Retina 2017 Aug;37(8):1620-1624

Department of Ophthalmology, Casey Eye Institute, Oregon Health and Science University, Portland, Oregon.

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http://dx.doi.org/10.1097/IAE.0000000000001672DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6699743PMC
August 2017

Probing the dynamics of N-methylacetamide in methanol via ab initio molecular dynamics.

Phys Chem Chem Phys 2017 May;19(20):12868-12875

ICMS, Department of Chemistry, Temple University, Philadelphia, 19122, USA.

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http://dx.doi.org/10.1039/c7cp00690jDOI Listing
May 2017

Small molecule modulation of voltage gated sodium channels.

Curr Opin Struct Biol 2017 04 28;43:156-162. Epub 2017 Mar 28.

Institute for Computational Molecular Science, Department of Chemistry, Temple University, Philadelphia, PA 19122, United States. Electronic address:

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http://dx.doi.org/10.1016/j.sbi.2017.02.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5420475PMC
April 2017

Effect of Interlayer Spacing on the Activity of Layered Manganese Oxide Bilayer Catalysts for the Oxygen Evolution Reaction.

J Am Chem Soc 2017 02 30;139(5):1863-1870. Epub 2017 Jan 30.

Department of Chemistry, Temple University , Beury Hall, 1901 North 13th Street, Philadelphia, Pennsylvania 19122, United States.

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http://pubs.acs.org/doi/10.1021/jacs.6b09184
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http://dx.doi.org/10.1021/jacs.6b09184DOI Listing
February 2017

Why Do Membranes of Some Unhealthy Cells Adopt a Cubic Architecture?

ACS Cent Sci 2016 Dec 5;2(12):943-953. Epub 2016 Dec 5.

Roy & Diana Vagelos Laboratories, Department of Chemistry, University of Pennsylvania , Philadelphia, Pennsylvania 19104-6323, United States.

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http://dx.doi.org/10.1021/acscentsci.6b00284DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5200934PMC
December 2016

A Free-Standing Molecular Spin-Charge Converter for Ubiquitous Magnetic-Energy Harvesting and Sensing.

Adv Mater 2017 Feb 20;29(8). Epub 2016 Dec 20.

Department of Mechanical Engineering and Temple Materials Institute, Temple University, Philadelphia, PA, 19122, USA.

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http://dx.doi.org/10.1002/adma.201605150DOI Listing
February 2017

On the role of water density fluctuations in the inhibition of a proton channel.

Proc Natl Acad Sci U S A 2016 12 12;113(52):E8359-E8368. Epub 2016 Dec 12.

Institute for Computational Molecular Science, Department of Chemistry, Temple University, Philadelphia, PA 19122;

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http://dx.doi.org/10.1073/pnas.1609964114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5206518PMC
December 2016

Complex Arrangement of Orthogonal Nanoscale Columns via a Supramolecular Orientational Memory Effect.

ACS Nano 2016 11 10;10(11):10480-10488. Epub 2016 Nov 10.

Institute of Computational Molecular Science, Temple University , Philadelphia, Pennsylvania 19122, United States.

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http://dx.doi.org/10.1021/acsnano.6b06419DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5292035PMC
November 2016

Understanding the self-assembly of amino ester-based benzene-1,3,5-tricarboxamides using molecular dynamics simulations.

Phys Chem Chem Phys 2016 Dec;19(1):258-266

Chemistry and Physics of Materials Unit, Jawaharlal Nehru Centre for Advanced Scientific Research, Bangalore 560 064, India.

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http://xlink.rsc.org/?DOI=C6CP06742E
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http://dx.doi.org/10.1039/c6cp06742eDOI Listing
December 2016

Fluorine-19 NMR and computational quantification of isoflurane binding to the voltage-gated sodium channel NaChBac.

Proc Natl Acad Sci U S A 2016 11 15;113(48):13762-13767. Epub 2016 Nov 15.

Department of Anesthesiology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261;

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http://dx.doi.org/10.1073/pnas.1609939113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5137747PMC
November 2016

Does Proton Conduction in the Voltage-Gated H Channel hHv1 Involve Grotthuss-Like Hopping via Acidic Residues?

J Phys Chem B 2017 04 18;121(15):3340-3351. Epub 2016 Nov 18.

Laboratory of Computational Chemistry and Biochemistry, Institute of Chemical Sciences and Engineering, École Polytechnique Fédérale de Lausanne (EPFL) , CH-1015 Lausanne, Switzerland.

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http://dx.doi.org/10.1021/acs.jpcb.6b08339DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6310143PMC
April 2017

Isolation of Acacetin from Calea urticifolia with Inhibitory Properties against Human Monoamine Oxidase-A and -B.

J Nat Prod 2016 10 18;79(10):2538-2544. Epub 2016 Oct 18.

Institute for Computational Molecular Science and Department of Chemistry, Temple University , Philadelphia, Pennsylvania 19122, United States.

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http://dx.doi.org/10.1021/acs.jnatprod.6b00440DOI Listing
October 2016

Accurate first-principles structures and energies of diversely bonded systems from an efficient density functional.

Nat Chem 2016 09 13;8(9):831-6. Epub 2016 Jun 13.

Department of Physics, Temple University, 1925 N 12th Street, Philadelphia, Pennsylvania 19122, USA.

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http://dx.doi.org/10.1038/nchem.2535DOI Listing
September 2016

Nickel Confined in the Interlayer Region of Birnessite: an Active Electrocatalyst for Water Oxidation.

Angew Chem Int Ed Engl 2016 08 6;55(35):10381-5. Epub 2016 May 6.

Department of Chemistry, Temple University, 1901 N. 13th Street, Philadelphia, PA, 19122, USA.

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http://dx.doi.org/10.1002/anie.201601935DOI Listing
August 2016

Bioactive cell-like hybrids coassembled from (glyco)dendrimersomes with bacterial membranes.

Proc Natl Acad Sci U S A 2016 Mar 16;113(9):E1134-41. Epub 2016 Feb 16.

Roy & Diana Vagelos Laboratories, Department of Chemistry, University of Pennsylvania, Philadelphia, PA 19104-6323;

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http://dx.doi.org/10.1073/pnas.1525589113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4780639PMC
March 2016

Molecular dynamics simulations of cholesterol-rich membranes using a coarse-grained force field for cyclic alkanes.

J Chem Phys 2015 Dec;143(24):243144

Institute for Computational Molecular Science, Temple University, 1925 North 12th Street, Philadelphia, Pennsylvania 19122-1801, USA.

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http://dx.doi.org/10.1063/1.4937153DOI Listing
December 2015

Coarse-grained molecular dynamics study of membrane fusion: Curvature effects on free energy barriers along the stalk mechanism.

J Chem Phys 2015 Dec;143(24):243112

Department of Applied Chemistry, Nagoya University, Furo-cho, Chikusa-ku, Nagoya, Aichi 464-8603, Japan.

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http://dx.doi.org/10.1063/1.4933087DOI Listing
December 2015

Understanding TRPV1 activation by ligands: Insights from the binding modes of capsaicin and resiniferatoxin.

Proc Natl Acad Sci U S A 2016 Jan 30;113(2):E137-45. Epub 2015 Dec 30.

Institute for Computational Molecular Science, Temple University, Philadelphia, PA 19122;

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http://dx.doi.org/10.1073/pnas.1517288113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4720335PMC
January 2016

A large genome-wide association study of age-related macular degeneration highlights contributions of rare and common variants.

Authors:
Lars G Fritsche Wilmar Igl Jessica N Cooke Bailey Felix Grassmann Sebanti Sengupta Jennifer L Bragg-Gresham Kathryn P Burdon Scott J Hebbring Cindy Wen Mathias Gorski Ivana K Kim David Cho Donald Zack Eric Souied Hendrik P N Scholl Elisa Bala Kristine E Lee David J Hunter Rebecca J Sardell Paul Mitchell Joanna E Merriam Valentina Cipriani Joshua D Hoffman Tina Schick Yara T E Lechanteur Robyn H Guymer Matthew P Johnson Yingda Jiang Chloe M Stanton Gabriëlle H S Buitendijk Xiaowei Zhan Alan M Kwong Alexis Boleda Matthew Brooks Linn Gieser Rinki Ratnapriya Kari E Branham Johanna R Foerster John R Heckenlively Mohammad I Othman Brendan J Vote Helena Hai Liang Emmanuelle Souzeau Ian L McAllister Timothy Isaacs Janette Hall Stewart Lake David A Mackey Ian J Constable Jamie E Craig Terrie E Kitchner Zhenglin Yang Zhiguang Su Hongrong Luo Daniel Chen Hong Ouyang Ken Flagg Danni Lin Guanping Mao Henry Ferreyra Klaus Stark Claudia N von Strachwitz Armin Wolf Caroline Brandl Guenther Rudolph Matthias Olden Margaux A Morrison Denise J Morgan Matthew Schu Jeeyun Ahn Giuliana Silvestri Evangelia E Tsironi Kyu Hyung Park Lindsay A Farrer Anton Orlin Alexander Brucker Mingyao Li Christine A Curcio Saddek Mohand-Saïd José-Alain Sahel Isabelle Audo Mustapha Benchaboune Angela J Cree Christina A Rennie Srinivas V Goverdhan Michelle Grunin Shira Hagbi-Levi Peter Campochiaro Nicholas Katsanis Frank G Holz Frédéric Blond Hélène Blanché Jean-François Deleuze Robert P Igo Barbara Truitt Neal S Peachey Stacy M Meuer Chelsea E Myers Emily L Moore Ronald Klein Michael A Hauser Eric A Postel Monique D Courtenay Stephen G Schwartz Jaclyn L Kovach William K Scott Gerald Liew Ava G Tan Bamini Gopinath John C Merriam R Theodore Smith Jane C Khan Humma Shahid Anthony T Moore J Allie McGrath Reneé Laux Milam A Brantley Anita Agarwal Lebriz Ersoy Albert Caramoy Thomas Langmann Nicole T M Saksens Eiko K de Jong Carel B Hoyng Melinda S Cain Andrea J Richardson Tammy M Martin John Blangero Daniel E Weeks Bal Dhillon Cornelia M van Duijn Kimberly F Doheny Jane Romm Caroline C W Klaver Caroline Hayward Michael B Gorin Michael L Klein Paul N Baird Anneke I den Hollander Sascha Fauser John R W Yates Rando Allikmets Jie Jin Wang Debra A Schaumberg Barbara E K Klein Stephanie A Hagstrom Itay Chowers Andrew J Lotery Thierry Léveillard Kang Zhang Murray H Brilliant Alex W Hewitt Anand Swaroop Emily Y Chew Margaret A Pericak-Vance Margaret DeAngelis Dwight Stambolian Jonathan L Haines Sudha K Iyengar Bernhard H F Weber Gonçalo R Abecasis Iris M Heid

Nat Genet 2016 Feb 21;48(2):134-43. Epub 2015 Dec 21.

Department of Genetic Epidemiology, University of Regensburg, Regensburg, Germany.

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http://dx.doi.org/10.1038/ng.3448DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4745342PMC
February 2016

High-resolution structures of the M2 channel from influenza A virus reveal dynamic pathways for proton stabilization and transduction.

Proc Natl Acad Sci U S A 2015 Nov 2;112(46):14260-5. Epub 2015 Nov 2.

Department of Pharmaceutical Chemistry, University of San Francisco, San Francisco, CA 94158;

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http://dx.doi.org/10.1073/pnas.1518493112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4655559PMC
November 2015

Frustrated Solvation Structures Can Enhance Electron Transfer Rates.

J Phys Chem Lett 2015 Dec 20;6(23):4804-8. Epub 2015 Nov 20.

Institute for Computational Molecular Science, ‡Department of Chemistry, and §Center for the Computational Design of Functional Layered Materials, Temple University , Philadelphia, Pennsylvania 19122, United States.

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http://dx.doi.org/10.1021/acs.jpclett.5b02277DOI Listing
December 2015

Understanding the Boron-Nitrogen Interaction and Its Possible Implications in Drug Design.

J Phys Chem B 2015 Nov 28;119(45):14393-401. Epub 2015 Oct 28.

Institute for Computational Molecular Science, Temple University , 1900 North 12th Street, Philadelphia, Pennsylvania 19122-6078, United States.

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http://dx.doi.org/10.1021/acs.jpcb.5b07783DOI Listing
November 2015

Reply: To PMID 25456150.

Ophthalmology 2015 Oct;122(10):e63

Center for Statistical Genetics, Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, Michigan.

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October 2015

Reply: To PMID 25456150.

Ophthalmology 2015 Oct;122(10):e61-2

Center for Statistical Genetics, Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, Michigan.

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October 2015

Reply: To PMID 25456150.

Ophthalmology 2015 Oct;122(10):e58-9

Center for Statistical Genetics, Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, Michigan.

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October 2015

Joint Associations of Diet, Lifestyle, and Genes with Age-Related Macular Degeneration.

Ophthalmology 2015 Nov 6;122(11):2286-94. Epub 2015 Sep 6.

Department of Ophthalmology and Visual Sciences, McPherson Eye Research Institute, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin. Electronic address:

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November 2015

Author reply: To PMID 24974817.

Ophthalmology 2015 Aug;122(8):e46-7

Center for Statistical Genetics, Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, Michigan.

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August 2015

Characterization of the honeybee AmNaV1 channel and tools to assess the toxicity of insecticides.

Sci Rep 2015 Jul 23;5:12475. Epub 2015 Jul 23.

1] Centre de recherche, Institut universitaire en santé mentale de Québec, Quebec City, QC, G1J 2G3 Canada [2] Department of Medicine, Université Laval, Quebec City, QC, G1K 7P4 Canada.

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July 2015

Comparative sequence analysis suggests a conserved gating mechanism for TRP channels.

J Gen Physiol 2015 Jul 15;146(1):37-50. Epub 2015 Jun 15.

Institute for Computational Molecular Science, Temple University, Philadelphia, PA 19122

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http://dx.doi.org/10.1085/jgp.201411329DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4485022PMC
July 2015

Flavonoids from Perovskia atriplicifolia and Their in Vitro Displacement of the Respective Radioligands for Human Opioid and Cannabinoid Receptors.

J Nat Prod 2015 Jun 2;78(6):1461-5. Epub 2015 Jun 2.

†Department of BioMolecular Sciences, Division of Medicinal Chemistry, School of Pharmacy, University of Mississippi, University, Mississippi 38677, United States.

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June 2015

Unraveling functional significance of natural variations of a human galectin by glycodendrimersomes with programmable glycan surface.

Proc Natl Acad Sci U S A 2015 May 20;112(18):5585-90. Epub 2015 Apr 20.

Roy & Diana Vagelos Laboratories, Department of Chemistry, University of Pennsylvania, Philadelphia, PA 19104-6323;

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http://dx.doi.org/10.1073/pnas.1506220112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4426414PMC
May 2015

Dissecting molecular aspects of cell interactions using glycodendrimersomes with programmable glycan presentation and engineered human lectins.

Angew Chem Int Ed Engl 2015 Mar 5;54(13):4036-40. Epub 2015 Feb 5.

Roy & Diana Vagelos Laboratories, Department of Chemistry, University of Pennsylvania, Philadelphia, Pennsylvania 19104-6323 (USA) http://percec02.chem.upenn.edu/

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http://dx.doi.org/10.1002/anie.201410882DOI Listing
March 2015

Gating pore currents are defects in common with two Nav1.5 mutations in patients with mixed arrhythmias and dilated cardiomyopathy.

J Gen Physiol 2015 Feb;145(2):93-106

Centre de Recherche de L'Institut Universitaire en Santé Mentale de Québec, Québec City, Québec G1J 2G3, Canada Department of Medicine, Université Laval, Québec City, Québec G1K 7P4, Canada

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http://dx.doi.org/10.1085/jgp.201411304DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4306709PMC
February 2015

Catalytic metal ions and enzymatic processing of DNA and RNA.

Acc Chem Res 2015 Feb 15;48(2):220-8. Epub 2015 Jan 15.

Department of Drug Discovery and Development, Istituto Italiano di Tecnologia , Via Morego 30, 16163 Genoa, Italy.

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February 2015

Free-energy landscape of ion-channel voltage-sensor-domain activation.

Proc Natl Acad Sci U S A 2015 Jan 22;112(1):124-9. Epub 2014 Dec 22.

Institute for Computational Molecular Science, Temple University, Philadelphia, PA 19122;

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http://dx.doi.org/10.1073/pnas.1416959112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4291615PMC
January 2015

Dehydration of multilamellar fatty acid membranes: towards a computational model of the stratum corneum.

J Chem Phys 2014 Dec;141(22):22D526

Institute for Computational Molecular Science, SERC Building (035-07), Temple University, 1925 North 12th Street, Philadelphia, Pennsylvania 19122, USA.

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http://aip.scitation.org/doi/10.1063/1.4902363
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December 2014