Michael L Gatza

Michael L Gatza

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Michael L Gatza

Michael L Gatza

Publications by authors named "Michael L Gatza"

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Integrative proteogenomic analyses of human tumours identifies ADNP as a novel oncogenic mediator of cell cycle progression in high-grade serous ovarian cancer with poor prognosis.

EBioMedicine 2019 Nov 22. Epub 2019 Nov 22.

Rutgers Cancer Institute of New Jersey, New Brunswick, NJ, United States; Department of Radiation Oncology, Robert Wood Johnson Medical School, United States; Rutgers, The State University of New Jersey, New Brunswick NJ, United States. Electronic address:

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http://dx.doi.org/10.1016/j.ebiom.2019.11.009DOI Listing
November 2019

Emerging Role of SOX Proteins in Breast Cancer Development and Maintenance.

J Mammary Gland Biol Neoplasia 2019 Sep 9;24(3):213-230. Epub 2019 May 9.

Rutgers Cancer Institute of New Jersey, 195 Little Albany Street, CINJ 4558, New Brunswick, NJ, 08903, USA.

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http://link.springer.com/10.1007/s10911-019-09430-6
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http://dx.doi.org/10.1007/s10911-019-09430-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6790170PMC
September 2019

Multi-omic Dissection of Oncogenically Active Epiproteomes Identifies Drivers of Proliferative and Invasive Breast Tumors.

iScience 2019 Jul 4;17:359-378. Epub 2019 Jul 4.

Department of Biochemistry & Biophysics, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA; Lineberger Comprehensive Cancer Center, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA. Electronic address:

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http://dx.doi.org/10.1016/j.isci.2019.07.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6660457PMC
July 2019

The Modulatory Role of MicroRNA-873 in the Progression of KRAS-Driven Cancers.

Mol Ther Nucleic Acids 2019 Mar 13;14:301-317. Epub 2018 Dec 13.

Department of Experimental Therapeutics, The University of Texas MD Anderson Cancer Center, Houston, TX, USA; Center for RNA Interference and Non-Coding RNAs, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. Electronic address:

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http://dx.doi.org/10.1016/j.omtn.2018.11.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6348737PMC
March 2019

Exosomal miRNA confers chemo resistance via targeting Cav1/p-gp/M2-type macrophage axis in ovarian cancer.

EBioMedicine 2018 Dec 25;38:100-112. Epub 2018 Nov 25.

Department of Experimental Therapeutics, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA; Center for RNA Interference and Non-Coding RNA, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA; Department of Cancer Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S23523964183049
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http://dx.doi.org/10.1016/j.ebiom.2018.11.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6306310PMC
December 2018

Recurrence analysis on prostate cancer patients with Gleason score 7 using integrated histopathology whole-slide images and genomic data through deep neural networks.

J Med Imaging (Bellingham) 2018 Oct 15;5(4):047501. Epub 2018 Nov 15.

Rutgers Cancer Institute of New Jersey, Department of Pathology and Laboratory Medicine, New Brunswick, New Jersey, United States.

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http://dx.doi.org/10.1117/1.JMI.5.4.047501DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6237203PMC
October 2018

Mediator kinase CDK8/CDK19 drives YAP1-dependent BMP4-induced EMT in cancer.

Oncogene 2018 08 21;37(35):4792-4808. Epub 2018 May 21.

Department of Chemistry and Biochemistry, University of South Carolina, Columbia, SC, USA.

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http://dx.doi.org/10.1038/s41388-018-0316-yDOI Listing
August 2018

New Mechanisms of Resistance to MEK Inhibitors in Melanoma Revealed by Intravital Imaging.

Cancer Res 2018 01 27;78(2):542-557. Epub 2017 Nov 27.

UNC Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.

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http://dx.doi.org/10.1158/0008-5472.CAN-17-1653DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6132242PMC
January 2018

Parkin targets HIF-1α for ubiquitination and degradation to inhibit breast tumor progression.

Nat Commun 2017 11 28;8(1):1823. Epub 2017 Nov 28.

Rutgers Cancer Institute of New Jersey, Robert Wood Johnson Medical School, Rutgers, State University of New Jersey, New Brunswick, NJ, 08903, USA.

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http://dx.doi.org/10.1038/s41467-017-01947-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5703960PMC
November 2017

NRF2 Induction Supporting Breast Cancer Cell Survival Is Enabled by Oxidative Stress-Induced DPP3-KEAP1 Interaction.

Cancer Res 2017 06 17;77(11):2881-2892. Epub 2017 Apr 17.

Department of Radiation Oncology, Rutgers Cancer Institute of New Jersey and Robert Wood Johnson Medical School, New Brunswick, New Jersey.

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http://dx.doi.org/10.1158/0008-5472.CAN-16-2204DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5464605PMC
June 2017

Amplification of SOX4 promotes PI3K/Akt signaling in human breast cancer.

Breast Cancer Res Treat 2017 04 7;162(3):439-450. Epub 2017 Feb 7.

Rutgers Cancer Institute of New Jersey, 195 Little Albany Street, CINJ 4558, New Brunswick, NJ, 08903, USA.

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http://dx.doi.org/10.1007/s10549-017-4139-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5334195PMC
April 2017

Another Breast Cancer Entity Confirmed: Genomics of Invasive Lobular Breast Cancer.

J Clin Oncol 2016 06 28;34(16):1838-9. Epub 2016 Mar 28.

University of North Carolina at Chapel Hill, Chapel Hill, NC

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http://dx.doi.org/10.1200/JCO.2015.66.3872DOI Listing
June 2016

An integrated genomics approach identifies drivers of proliferation in luminal-subtype human breast cancer.

Nat Genet 2014 Oct 24;46(10):1051-9. Epub 2014 Aug 24.

1] Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA. [2] Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA. [3] Curriculum in Bioinformatics and Computational Biology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA. [4] Department of Pathology and Laboratory Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.

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http://dx.doi.org/10.1038/ng.3073DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4300117PMC
October 2014

FOXO transcription factors control E2F1 transcriptional specificity and apoptotic function.

Cancer Res 2013 Oct 21;73(19):6056-67. Epub 2013 Aug 21.

Authors' Affiliations: Duke Institute for Genome Sciences and Policy, Department of Molecular Genetics and Microbiology, Duke University Medical Center; Department of Biomedical Engineering, Duke University, Durham, North Carolina.

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http://dx.doi.org/10.1158/0008-5472.CAN-13-0453DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3815650PMC
October 2013

Interaction of E2F7 transcription factor with E2F1 and C-terminal-binding protein (CtBP) provides a mechanism for E2F7-dependent transcription repression.

J Biol Chem 2013 Aug 13;288(34):24581-9. Epub 2013 Jul 13.

Duke Institute for Genome Sciences and Policy, Department of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, North Carolina 27708, USA.

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http://dx.doi.org/10.1074/jbc.M113.467506DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3750156PMC
August 2013

SIGNATURE: a workbench for gene expression signature analysis.

BMC Bioinformatics 2011 Nov 14;12:443. Epub 2011 Nov 14.

Department of Integrative Biology and Pharmacology, University of Texas Health Science Center at Houston, Houston, TX, USA.

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http://dx.doi.org/10.1186/1471-2105-12-443DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3251189PMC
November 2011

Analysis of tumor environmental response and oncogenic pathway activation identifies distinct basal and luminal features in HER2-related breast tumor subtypes.

Breast Cancer Res 2011 Jun 7;13(3):R62. Epub 2011 Jun 7.

Duke Institute for Genome Sciences and Policy, Duke University Medical Center, Durham, NC 27708, USA.

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http://dx.doi.org/10.1186/bcr2899DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3218951PMC
June 2011

Using a stem cell-based signature to guide therapeutic selection in cancer.

Cancer Res 2011 Mar 17;71(5):1772-80. Epub 2010 Dec 17.

Duke Institute for Genome Sciences and Policy, Duke University, Durham, North Carolina 27710, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-10-1735DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3049992PMC
March 2011

A pathway-based classification of human breast cancer.

Proc Natl Acad Sci U S A 2010 Apr 24;107(15):6994-9. Epub 2010 Mar 24.

Duke Institute for Genome Sciences and Policy, Duke University Medical Center, Durham, NC 27710, USA.

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http://dx.doi.org/10.1073/pnas.0912708107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2872436PMC
April 2010

Genetic heterogeneity of Myc-induced mammary tumors reflecting diverse phenotypes including metastatic potential.

Proc Natl Acad Sci U S A 2009 Sep 4;106(38):16387-92. Epub 2009 Sep 4.

Duke Institute for Genome Sciences and Policy, Department of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, NC 27710, USA.

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http://dx.doi.org/10.1073/pnas.0901250106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2752567PMC
September 2009

Ubiquitination of HTLV-I Tax in response to DNA damage regulates nuclear complex formation and nuclear export.

Retrovirology 2007 Dec 14;4:95. Epub 2007 Dec 14.

Department of Molecular Virology and Microbiology, Interdepartmental Program in Cell and Molecular Biology, Baylor College of Medicine, Houston, Texas 77030, USA.

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http://dx.doi.org/10.1186/1742-4690-4-95DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2234431PMC
December 2007

Genotoxic stress and cellular stress alter the subcellular distribution of human T-cell leukemia virus type 1 tax through a CRM1-dependent mechanism.

J Virol 2006 Jul;80(13):6657-68

Department of Molecular Virology and Microbiology, Baylor College of Medicine, One Baylor Plaza MS-385, Houston, TX 77030, USA.

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http://jvi.asm.org/cgi/doi/10.1128/JVI.02270-05
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http://dx.doi.org/10.1128/JVI.02270-05DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1488944PMC
July 2006

Impact of transforming viruses on cellular mutagenesis, genome stability, and cellular transformation.

Environ Mol Mutagen 2005 Mar-Apr;45(2-3):304-25

Interdepartmental Program in Cell and Molecular Biology, Baylor College of Medicine, Houston, Texas 77030, USA.

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http://dx.doi.org/10.1002/em.20088DOI Listing
June 2005

Cellular transformation by the HTLV-I Tax protein, a jack-of-all-trades.

Oncogene 2003 Aug;22(33):5141-9

Interdepartmental Program in Cell and Molecular Biology, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA.

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http://dx.doi.org/10.1038/sj.onc.1206549DOI Listing
August 2003