Publications by authors named "Michael Kovermann"

40 Publications

Template-assisted design of monomeric polyQ models to unravel the unique role of glutamine side chains in disease-related aggregation.

Chem Sci 2021 Jan 28;12(1):412-426. Epub 2020 Oct 28.

Department of Chemistry , University of Konstanz , 78457 Konstanz , Germany . Email: ; Email:

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January 2021

All atom insights into the impact of crowded environments on protein stability by NMR spectroscopy.

Nat Commun 2020 11 13;11(1):5760. Epub 2020 Nov 13.

Department of Chemistry, University of Konstanz, Universitätsstrasse. 10, 78457, Konstanz, Germany.

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November 2020

Synthesis of nickel hexacyanoferrate nanocubes with tuneable dimensions temperature-controlled Ni-citrate complexation.

Chem Commun (Camb) 2020 Nov;56(92):14439-14442

Physical Chemistry, Department of Chemistry, University of Konstanz, Universitätsstrasse 10, D-78457 Konstanz, Germany.

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November 2020

Insights into Protein Stability in Cell Lysate by F NMR Spectroscopy.

Chembiochem 2020 Dec 16;21(24):3575-3579. Epub 2020 Sep 16.

Department of Chemistry, University Konstanz, Research School Chemical Biology (KoRS-CB), Universitätsstrasse 10, 78457, Konstanz, Germany.

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December 2020

What does fluorine do to a protein? Thermodynamic, and highly-resolved structural insights into fluorine-labelled variants of the cold shock protein.

Sci Rep 2020 02 14;10(1):2640. Epub 2020 Feb 14.

Department of Chemistry, Universitätsstrasse 10, Universität Konstanz, DE-78457, Konstanz, Germany.

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February 2020

Conformational and functional characterization of artificially conjugated non-canonical ubiquitin dimers.

Sci Rep 2019 12 27;9(1):19991. Epub 2019 Dec 27.

Department of Chemistry, Universitätsstrasse 10, Universität Konstanz, DE-78457, Konstanz, Germany.

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December 2019

Liquid Metastable Precursors of Ibuprofen as Aqueous Nucleation Intermediates.

Angew Chem Int Ed Engl 2019 12 6;58(52):19103-19109. Epub 2019 Nov 6.

Physical Chemistry, University of Konstanz, Universitätsstraße 10, 78457, Konstanz, Germany.

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December 2019

Structural and catalytic insights into HoLaMa, a derivative of Klenow DNA polymerase lacking the proofreading domain.

PLoS One 2019 10;14(4):e0215411. Epub 2019 Apr 10.

Department of Pharmacy and Biotechnology, University of Bologna, Bologna, Italy.

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January 2020

Artificially Linked Ubiquitin Dimers Characterised Structurally and Dynamically by NMR Spectroscopy.

Chembiochem 2019 07 24;20(14):1772-1777. Epub 2019 Jun 24.

Universität Konstanz, Chemie, Universitätsstrasse 10, 78457, Konstanz, Germany.

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July 2019

Targeted expression and purification of fluorine labelled cold shock protein B by using an auxotrophic strategy.

Protein Expr Purif 2019 05 6;157:86-91. Epub 2019 Feb 6.

Department of Chemistry, University Konstanz, DE-78464 Konstanz, Germany; Konstanz Research School Chemical Biology (KoRS-CB), University Konstanz, DE-78464 Konstanz, Germany. Electronic address:

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May 2019

Macromolecular Crowding Tunes Protein Stability by Manipulating Solvent Accessibility.

Chembiochem 2019 03 11;20(6):759-763. Epub 2019 Feb 11.

Fachbereich Chemie, Universität Konstanz, Universitätsstrasse 10, 78457, Konstanz, Germany.

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March 2019

A Luminal Loop of Wilson Disease Protein Binds Copper and Is Required for Protein Activity.

Biophys J 2018 09 16;115(6):1007-1018. Epub 2018 Aug 16.

Department of Biology and Biological Engineering, Chalmers University of Technology, Gothenburg, Sweden. Electronic address:

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September 2018

Structure-Based Insights into the Dynamics and Function of Two-Domain SlpA from Escherichia coli.

Biochemistry 2017 Dec 1;56(50):6533-6543. Epub 2017 Dec 1.

Institut für Physik, Biophysik, Martin-Luther-Universität Halle-Wittenberg , D-06099 Halle (Saale), Germany.

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December 2017

Structural basis for ligand binding to an enzyme by a conformational selection pathway.

Proc Natl Acad Sci U S A 2017 06 30;114(24):6298-6303. Epub 2017 May 30.

Department of Chemistry, Umeå University, SE-901 87 Umeå, Sweden;

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June 2017

Linkage between Fitness of Yeast Cells and Adenylate Kinase Catalysis.

PLoS One 2016 19;11(9):e0163115. Epub 2016 Sep 19.

Department of Chemistry, Umeå University, SE-901 87, Umeå, Sweden.

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August 2017

Protein dynamics and function from solution state NMR spectroscopy.

Q Rev Biophys 2016 ;49:e6

Department of Chemistry,Umeå University,SE-901 87 Umeå,Sweden.

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October 2016

The C-Terminus of Human Copper Importer Ctr1 Acts as a Binding Site and Transfers Copper to Atox1.

Biophys J 2016 Jan;110(1):95-102

Chemistry Department, Umeå University, Umeå, Sweden; Department of Biology and Biological Engineering, Chalmers University of Technology, Gothenburg, Sweden. Electronic address:

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January 2016

High-resolution structures of the D-alanyl carrier protein (Dcp) DltC from Bacillus subtilis reveal equivalent conformations of apo- and holo-forms.

FEBS Lett 2015 Aug 17;589(18):2283-9. Epub 2015 Jul 17.

Institut für Biochemie und Biotechnologie, Martin-Luther Universität Halle-Wittenberg, Kurt-Mothes Strasse 3, D-06120 Halle/Saale, Germany. Electronic address:

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August 2015

Structural basis for catalytically restrictive dynamics of a high-energy enzyme state.

Nat Commun 2015 Jul 3;6:7644. Epub 2015 Jul 3.

Department of Chemistry, Chemical Biological Centre, Umeå University, Umeå 90187, Sweden.

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July 2015

Novel sulfated phosphoglycolipids from Natronomonas moolapensis.

Chem Phys Lipids 2015 Oct 29;191:8-15. Epub 2015 Jun 29.

Max Planck Institute of Biochemistry, Am Klopferspitz 18, 82152 Martinsried, Germany.

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October 2015

Solution structure of the PsIAA4 oligomerization domain reveals interaction modes for transcription factors in early auxin response.

Proc Natl Acad Sci U S A 2015 May 27;112(19):6230-5. Epub 2015 Apr 27.

Department of Molecular Signal Processing, Leibniz Institute of Plant Biochemistry, D-06120 Halle, Germany; Institute of Biochemistry and Biotechnology, Martin Luther University Halle-Wittenberg, D-06120 Halle, Germany; and Department of Plant Sciences, University of California, Davis, CA 95616

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May 2015

Initiation of RNA synthesis by the hepatitis C virus RNA-dependent RNA polymerase is affected by the structure of the RNA template.

Biochemistry 2014 Nov 31;53(44):7002-12. Epub 2014 Oct 31.

Institute of Biochemistry and Biotechnology, Section of Microbial Biotechnology, ‡Institute of Physics, Section of Biophysics, §Institute of Biochemistry and Biotechnology, Section of Technical Biochemistry, Martin Luther University Halle-Wittenberg , D-06120 Halle/Saale, Germany.

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November 2014

Molecular function of the prolyl cis/trans isomerase and metallochaperone SlyD.

Biol Chem 2013 Aug;394(8):965-75

Institut für Physik, Biophysik, und Mitteldeutsches Zentrum für Struktur und Dynamik der Proteine MZP, Martin-Luther Universität Halle-Wittenberg, D-06120 Halle, Germany.

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August 2013

Dynamic control of the prolyl isomerase function of the dual-domain SlyD protein.

Biophys Chem 2013 Jan 8;171:16-23. Epub 2012 Dec 8.

Institut für Physik, Biophysik, Martin-Luther-Universität Halle-Wittenberg, D-06099 Halle (Saale), Germany.

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January 2013

Optimisation of over-expression in E. coli and biophysical characterisation of human membrane protein synaptogyrin 1.

PLoS One 2012 1;7(6):e38244. Epub 2012 Jun 1.

Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden.

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October 2012

Real-time observation of polymer network formation by liquid- and solid-state NMR revealing multistage reaction kinetics.

J Phys Chem B 2012 Jun 14;116(25):7566-74. Epub 2012 Jun 14.

Institut für Physik-Biophysik, Martin-Luther-Universität Halle-Wittenberg, Betty-Heimann-Str. 7, D-06120 Halle, Germany.

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June 2012

New binding mode to TNF-alpha revealed by ubiquitin-based artificial binding protein.

PLoS One 2012 20;7(2):e31298. Epub 2012 Feb 20.

Institute of Biochemistry and Biotechnology, Martin Luther University Halle-Wittenberg, Halle, Germany.

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June 2012