Michael K Schultz

Michael K Schultz

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Michael K Schultz

Michael K Schultz

Publications by authors named "Michael K Schultz"

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33Publications

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Optimizing the radiosynthesis of [Ga]DOTA-MLN6907 peptide containing three disulfide cyclization bonds - a GCC specific chelate for clinical radiopharmaceuticals.

Appl Radiat Isot 2018 Oct 9;140:333-341. Epub 2018 Aug 9.

Department of Radiology, The University of Iowa, 200 Hawkins Drive, Iowa City, IA 52242, USA; Departments of Radiation Oncology (Free Radical and Radiation Biology Program), Pediatrics, and Chemistry, and the Interdisciplinary Program in Human Toxicology, The University of Iowa, 500 N Road, ML B180, FRRB, Iowa City, IA, USA. Electronic address:

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October 2018

Modeling Cell and Tumor-Metastasis Dosimetry with the Particle and Heavy Ion Transport Code System (PHITS) Software for Targeted Alpha-Particle Radionuclide Therapy.

Radiat Res 2018 09 26;190(3):236-247. Epub 2018 Jun 26.

a   Interdisciplinary Graduate Program in Human Toxicology, The University of Iowa, Iowa City, Iowa.

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September 2018

Temporal characterization of flowback and produced water quality from a hydraulically fractured oil and gas well.

Sci Total Environ 2017 Oct 25;596-597:369-377. Epub 2017 Apr 25.

Department of Civil, Environmental, and Architectural Engineering, University of Colorado, UCB 607, Boulder, CO 80309, USA. Electronic address:

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October 2017

Automated cassette-based production of high specific activity [Pb]peptide-based theranostic radiopharmaceuticals for image-guided radionuclide therapy for cancer.

Appl Radiat Isot 2017 Sep 10;127:52-60. Epub 2017 May 10.

Interdisciplinary Graduate Program in Human Toxicology, University of Iowa, Iowa City, IA, USA; Stead Family Department of Pediatrics, University of Iowa, Iowa City, IA, USA; Department of Radiology, The University of Iowa, Iowa City, IA, USA; Viewpoint Molecular Targeting, LLC, Coralville, IA, USA; Department of Radiation Oncology (Free Radical and Radiation Biology Program), Carver College of Medicine, University of Iowa, Iowa City, IA, USA; Department of Chemistry, University of Iowa, Iowa City, IA, USA. Electronic address:

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September 2017

Mitochondrial-Targeted Decyl-Triphenylphosphonium Enhances 2-Deoxy-D-Glucose Mediated Oxidative Stress and Clonogenic Killing of Multiple Myeloma Cells.

PLoS One 2016 30;11(11):e0167323. Epub 2016 Nov 30.

Interdisciplinary Graduate Program in Molecular and Cellular Biology, University of Iowa, Iowa City, IA, United States of America.

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July 2017

Synthesis and Evaluation of Tetraarylethylene-based Mono-, Bis-, and Tris(pyridinium) Derivatives for Image-Guided Mitochondria-Specific Targeting and Cytotoxicity of Metastatic Melanoma Cells.

Bioconjug Chem 2016 Oct 23;27(10):2424-2430. Epub 2016 Sep 23.

Departments of Radiology and Radiation Oncology, Free Radical and Radiation Biology Program and ‡Department of Chemistry, The University of Iowa , Iowa City, Iowa 52242, United States.

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October 2016

Radiolabeling of DOTA-like conjugated peptides with generator-produced (68)Ga and using NaCl-based cationic elution method.

Nat Protoc 2016 06 12;11(6):1057-66. Epub 2016 May 12.

Departments of Radiology and Radiation Oncology (Free Radical Radiation Biology Program), University of Iowa, Iowa City, Iowa, USA.

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June 2016

Partitioning of naturally-occurring radionuclides (NORM) in Marcellus Shale produced fluids influenced by chemical matrix.

Environ Sci Process Impacts 2016 Apr 8;18(4):456-63. Epub 2016 Mar 8.

Interdisciplinary Human Toxicology Program, University of Iowa, ML B180 FRRB, 500 Newton Road, Iowa City, Iowa, USA 52242.

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April 2016

Investigation of the tritium content in surface water, bottom sediments (zoobenthos), macrophytes, and fish in the mid-stream region of the Yenisei River (Siberia, Russia).

Environ Sci Pollut Res Int 2015 Nov 16;22(22):18127-36. Epub 2015 Jul 16.

Department of Radiology, Free Radical and Radiation Biology Program, The University of Iowa, Iowa City, IA, USA.

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November 2015

Monitoring radionuclides in subsurface drinking water sources near unconventional drilling operations: a pilot study.

J Environ Radioact 2015 Apr 23;142:24-8. Epub 2015 Jan 23.

Interdisciplinary Human Toxicology Program, University of Iowa, Iowa City, IA 52242, USA; Departments of Radiology and Radiation Oncology, Free Radical and Radiation Biology Program, Medical Scientist Training Program, University of Iowa, Iowa City, IA 52242, USA. Electronic address:

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April 2015

A simple-rapid method to separate uranium, thorium, and protactinium for U-series age-dating of materials.

J Environ Radioact 2014 Aug 28;134:66-74. Epub 2014 Mar 28.

Departments of Radiology and Radiation Oncology, Free Radical and Radiation Biology Program, Interdisciplinary Human Toxicology Program, The University of Iowa, ML B180 FRRB, 500 Newton Road, Iowa City, IA 52246, USA. Electronic address:

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August 2014

Locally targeted delivery of a micron-size radiation therapy source using temperature-sensitive hydrogel.

Int J Radiat Oncol Biol Phys 2014 Apr 1;88(5):1142-7. Epub 2014 Feb 1.

Department of Biomedical Engineering, The University of Iowa, Iowa City, Iowa.

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April 2014

A new automated NaCl based robust method for routine production of gallium-68 labeled peptides.

Appl Radiat Isot 2013 Jun 31;76:46-54. Epub 2012 Aug 31.

Department of Radiology, The University of Iowa, 200 Hawkins Drive, Iowa City, IA 52242, USA.

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June 2013

Simplified NaCl based (68)Ga concentration and labeling procedure for rapid synthesis of (68)Ga radiopharmaceuticals in high radiochemical purity.

Bioconjug Chem 2012 Aug 19;23(8):1712-7. Epub 2012 Jul 19.

Zentralklinik Bad Berka, Department of Nuclear Medicine/PET Center, 99437 Bad Berka, Germany.

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August 2012

Second world congress on 68Ga molecular imaging.

J Nucl Med 2012 Jul;53(7):14N

University of Iowa, Iowa City, IA, USA.

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July 2012

Improved synthesis and biological evaluation of chelator-modified α-MSH analogs prepared by copper-free click chemistry.

Bioorg Med Chem Lett 2011 Oct 8;21(19):5757-61. Epub 2011 Aug 8.

Department of Radiology, Carver College of Medicine, The University of Iowa, 500 Newton Road, ML B180, Iowa City, IA 52242, USA.

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October 2011

Synthesis and radiolabeling of chelator-RNA aptamer bioconjugates with copper-64 for targeted molecular imaging.

Bioorg Med Chem 2011 Jul 14;19(13):4080-90. Epub 2011 May 14.

Department of Radiation Oncology, University of Iowa, Iowa City, IA 52242, United States.

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July 2011

Preparation of a versatile bifunctional zeolite for targeted imaging applications.

Langmuir 2011 Mar 9;27(6):2904-9. Epub 2011 Feb 9.

Department of Chemistry, University of Iowa , Iowa City, Iowa 52242, United States.

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March 2011

A DOTA-peptide conjugate by copper-free click chemistry.

Bioorg Med Chem Lett 2010 Aug 25;20(16):4805-7. Epub 2010 Jun 25.

Department of Pediatrics, Carver College of Medicine, University of Iowa, 4235 MERF 375 Newton Road, Iowa City, IA 52242, USA.

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August 2010

Synthesis of a DOTA--biotin conjugate for radionuclide chelation via Cu-free click chemistry.

Org Lett 2010 May;12(10):2398-401

Department of Radiology and Radiation Oncology, Carver College of Medicine, University of Iowa, Iowa City, Iowa 52242, USA.

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May 2010

Investigation of the pharmacokinetics of 3'-deoxy-3'-[18F]fluorothymidine uptake in the bone marrow before and early after initiation of chemoradiation therapy in head and neck cancer.

Nucl Med Biol 2010 May;37(4):433-8

Division of Nuclear Medicine, Department of Radiology, University of Iowa Hospitals and Clinics Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, IA 52242, USA.

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May 2010

Kinetic analysis of 3'-deoxy-3'-(18)F-fluorothymidine ((18)F-FLT) in head and neck cancer patients before and early after initiation of chemoradiation therapy.

J Nucl Med 2009 Jul 12;50(7):1028-35. Epub 2009 Jun 12.

Department of Radiology, Division of Nuclear Medicine, University of Iowa Hospitals and Clinics, Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, Iowa, USA.

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July 2009

A performance evaluation of 90Y dose-calibrator measurements in nuclear pharmacies and clinics in the United States.

Appl Radiat Isot 2008 Feb 18;66(2):252-60. Epub 2007 Sep 18.

The National Institute of Standards and Technology, Nuclear Medicine Standards Program, 100 Bureau Drive, MS 8462, Gaithersburg, MD 20899, USA.

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February 2008

An assessment of radionuclidic impurities of (210)Po produced via neutron irradiation of (209)Bi for use in targeted alpha-particle radiotherapy.

Appl Radiat Isot 2007 Jul 19;65(7):784-92. Epub 2007 Mar 19.

National Institute of Standards and Technology, Nuclear Medicine Standards Program, 100 Bureau Drive MS 8462, Gaithersburg, MD 20899, USA.

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July 2007

Assessing the 210At impurity in the production of 211At for radiotherapy by 210Po analysis via isotope dilution alpha spectrometry.

Appl Radiat Isot 2006 Oct-Nov;64(10-11):1365-9. Epub 2006 Mar 23.

National Institute of Standards and Technology, Radioactivity Group, 100 Bureau Drive MS8462, Gaithersburg, MD 21702, USA.

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November 2006

Enrichment of excess 210Po in anoxic ponds.

Environ Sci Technol 2005 Jul;39(13):4894-9

School of Earth and Environmental Sciences/RIO, College of Natural Sciences, Seoul National University, Seoul 151-742, Korea.

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July 2005