Michael J Weber

Michael J Weber

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Michael J Weber

Michael J Weber

Publications by authors named "Michael J Weber"

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Factors influencing fish mercury concentrations in Iowa rivers.

Ecotoxicology 2019 Mar 21;28(2):229-241. Epub 2019 Jan 21.

Iowa Department of Natural Resources, 15053 Hatchery Pl., Moravia, IA, 52571, USA.

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http://dx.doi.org/10.1007/s10646-019-02017-1DOI Listing
March 2019

A case study and a meta-analysis of seasonal variation in fish mercury concentrations.

Ecotoxicology 2018 Aug 10;27(6):641-649. Epub 2018 May 10.

Department of Natural Resource Ecology and Management, 339 Science Hall II, Iowa State University, Ames, IA, 50011, USA.

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http://dx.doi.org/10.1007/s10646-018-1942-4DOI Listing
August 2018

Symmetry breaking in spreading RAT2 fibroblasts requires the MAPK/ERK pathway scaffold RACK1 that integrates FAK, p190A-RhoGAP and ERK2 signaling.

Biochim Biophys Acta 2016 09 19;1863(9):2189-200. Epub 2016 May 19.

Institute of Microbiology AS CR, Prague, Czech Republic. Electronic address:

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http://dx.doi.org/10.1016/j.bbamcr.2016.05.013DOI Listing
September 2016

Synergistic apoptosis in head and neck squamous cell carcinoma cells by co-inhibition of insulin-like growth factor-1 receptor signaling and compensatory signaling pathways.

Head Neck 2015 Dec 6;37(12):1722-32. Epub 2015 Apr 6.

Department of Otolaryngology - Head and Neck Surgery, University of Virginia Health System, Charlottesville, Virginia.

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http://dx.doi.org/10.1002/hed.23822DOI Listing
December 2015

Integrin adjunct therapy for melanoma.

Pigment Cell Melanoma Res 2015 Jan 3;28(1):114-6. Epub 2014 Nov 3.

Department of Radiation Oncology, University of Virginia, Charlottesville, VA, USA; Robert M. Berne Cardiovascular Research Center, University of Virginia, Charlottesville, VA, USA.

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http://dx.doi.org/10.1111/pcmr.12320DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6542633PMC
January 2015

p70S6 kinase is a critical node that integrates HER-family and PI3 kinase signaling networks.

Cell Signal 2014 Aug 21;26(8):1627-35. Epub 2014 Mar 21.

Department of Microbiology, Immunology, and Cancer Biology, University of Virginia, Charlottesville, VA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cellsig.2014.03.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4091927PMC
August 2014

The reorientation of cell nucleus promotes the establishment of front-rear polarity in migrating fibroblasts.

J Mol Biol 2013 Jun 21;425(11):2039-2055. Epub 2013 Mar 21.

Institute of Microbiology, Academy of Sciences of the Czech Republic, Prague, Czech Republic. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00222836130017
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http://dx.doi.org/10.1016/j.jmb.2013.02.034DOI Listing
June 2013

Combinatorial drug screening identifies compensatory pathway interactions and adaptive resistance mechanisms.

Oncotarget 2013 Apr;4(4):622-35

Department of Microbiology, Immunology and Cancer Biology, University of Virginia, Charlottesville, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3720609PMC
http://dx.doi.org/10.18632/oncotarget.938DOI Listing
April 2013

Synthetic lethal screening with small-molecule inhibitors provides a pathway to rational combination therapies for melanoma.

Mol Cancer Ther 2012 Nov 7;11(11):2505-15. Epub 2012 Sep 7.

Department of Microbiology, Immunology, and Cancer Biology, University of Virginia, Jordan Hall Rm 2-16, Box 800734, 1300 Jefferson Park Avenue, Charlottesville, VA 22908, USA.

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http://mct.aacrjournals.org/cgi/doi/10.1158/1535-7163.MCT-12
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http://dx.doi.org/10.1158/1535-7163.MCT-12-0461DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3496043PMC
November 2012

Efficient identification of novel leads by dynamic focused screening: PDK1 case stud.

Comb Chem High Throughput Screen 2010 Jan;13(1):16-26

Drug Design and Optimization, Boston, MA 02115, USA.

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http://dx.doi.org/10.2174/138620710790218186DOI Listing
January 2010

The neuroendocrine-derived peptide parathyroid hormone-related protein promotes prostate cancer cell growth by stabilizing the androgen receptor.

Cancer Res 2009 Sep 25;69(18):7402-11. Epub 2009 Aug 25.

Department of Microbiology and Cancer Center, University of Virginia Health System, Charlottesville, Virginia 22908-0734, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-08-4687DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2803023PMC
September 2009

Rap2 regulates androgen sensitivity in human prostate cancer cells.

Prostate 2007 Oct;67(14):1590-9

Department of Molecular Physiology and Biological Physics, University of Virginia Health Sciences Center, Charlottesville, Virginia 22908, USA.

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http://dx.doi.org/10.1002/pros.20644DOI Listing
October 2007

Subcellular localization modulates activation function 1 domain phosphorylation in the androgen receptor.

Mol Endocrinol 2007 Sep 19;21(9):2071-84. Epub 2007 Jun 19.

Center for Cell Signaling, Department of Microbiology, University of Virginia Health System, Charlottesville, Virginia 22908, USA.

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http://dx.doi.org/10.1210/me.2007-0240DOI Listing
September 2007

Epinephrine protects cancer cells from apoptosis via activation of cAMP-dependent protein kinase and BAD phosphorylation.

J Biol Chem 2007 May 12;282(19):14094-100. Epub 2007 Mar 12.

Department of Cancer Biology, Section on Comparative Medicine, and Center for Human Genomics, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA.

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http://dx.doi.org/10.1074/jbc.M611370200DOI Listing
May 2007

Receptor for activated C kinase 1 (RACK1) and Src regulate the tyrosine phosphorylation and function of the androgen receptor.

Cancer Res 2006 Nov;66(22):11047-54

Department of Microbiology and Cancer Center, University of Virginia Health System, Charlottesville, Virginia, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-06-0596DOI Listing
November 2006

Stress kinase signaling regulates androgen receptor phosphorylation, transcription, and localization.

Mol Endocrinol 2006 Mar 10;20(3):503-15. Epub 2005 Nov 10.

Department of Microbiology, P.O. Box 800734, University of Virginia Health System, Charlottesville, Virginia 22908, USA.

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http://dx.doi.org/10.1210/me.2005-0351DOI Listing
March 2006

MEK partner 1 (MP1): regulation of oligomerization in MAP kinase signaling.

J Cell Biochem 2005 Mar;94(4):708-19

Department of Microbiology and Cancer Center, School of Medicine, University of Virginia, Charlottesville, VA 22908, USA.

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http://dx.doi.org/10.1002/jcb.20344DOI Listing
March 2005

The androgen receptor acetylation site regulates cAMP and AKT but not ERK-induced activity.

J Biol Chem 2004 Jul 30;279(28):29436-49. Epub 2004 Apr 30.

Department of Oncology, Georgetown University Medical Center, Washington, D C 20057, USA.

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http://dx.doi.org/10.1074/jbc.M313466200DOI Listing
July 2004

Transient, ligand-dependent arrest of the androgen receptor in subnuclear foci alters phosphorylation and coactivator interactions.

Mol Endocrinol 2004 Apr 18;18(4):834-50. Epub 2003 Dec 18.

Center for Cell Signaling, Department of Biochemistry and Molecular Genetics, Box 800577 Health Systems, University of Virginia, Charlottesville, VA 22908, USA.

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http://dx.doi.org/10.1210/me.2003-0145DOI Listing
April 2004

Identifying specific kinase substrates through engineered kinases and ATP analogs.

Methods 2004 Apr;32(4):389-97

Department of Microbiology and Cancer Center, University of Virginia, Health Science Center, Charlottesville, VA 22908, USA.

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http://dx.doi.org/10.1016/j.ymeth.2003.10.002DOI Listing
April 2004

Ras signaling in prostate cancer progression.

J Cell Biochem 2004 Jan;91(1):13-25

Department of Microbiology and Cancer Center, University of Virginia Health System, Charlottesville, Virginia 22908, USA.

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http://dx.doi.org/10.1002/jcb.10683DOI Listing
January 2004

Raffling off the effectors of Ras.

Authors:
Michael J Weber

Cancer Biol Ther 2003 Jan-Feb;2(1):76-7

Univ. of Virginia School of Medicine; 2-16 Jordan Hall; Charlottesville, Virginia 22908 USA.

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http://dx.doi.org/10.4161/cbt.193DOI Listing
July 2003

Identification of novel ERK2 substrates through use of an engineered kinase and ATP analogs.

J Biol Chem 2003 Apr 19;278(17):14926-35. Epub 2003 Feb 19.

Department of Microbiology and Cancer Center, University of Virginia Health Sciences Center, Charlottesville, Virginia 22908, USA.

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http://dx.doi.org/10.1074/jbc.M300485200DOI Listing
April 2003

Attenuation of Ras signaling restores androgen sensitivity to hormone-refractory C4-2 prostate cancer cells.

Cancer Res 2003 Apr;63(8):1975-80

Department of Microbiology, Cancer Center and Paul Mellon Prostate Cancer Institute, Charlottesville, Virginia 22908, USA.

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April 2003

Constitutive activation of the Ras/mitogen-activated protein kinase signaling pathway promotes androgen hypersensitivity in LNCaP prostate cancer cells.

Cancer Res 2003 Apr;63(8):1981-9

Department of Microbiology and Cancer Center and Paul Mellon Prostate Cancer Research Institute, University of Virginia, Charlottesville, Virginia 22908, USA.

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http://cancerres.aacrjournals.org/content/63/8/1981.full.pdf
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April 2003

Rac-PAK signaling stimulates extracellular signal-regulated kinase (ERK) activation by regulating formation of MEK1-ERK complexes.

Mol Cell Biol 2002 Sep;22(17):6023-33

Department of Microbiology, School of Medicine, University of Virginia, Charlottesville, Virginia 22908, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC134005PMC
http://dx.doi.org/10.1128/mcb.22.17.6023-6033.2002DOI Listing
September 2002

Androgen receptor phosphorylation. Regulation and identification of the phosphorylation sites.

J Biol Chem 2002 Aug 15;277(32):29304-14. Epub 2002 May 15.

Department of Microbiology and Cancer Center, University of Virginia Health Sciences Center, Charlottesville, Virginia 22908, USA.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M204131200
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http://dx.doi.org/10.1074/jbc.M204131200DOI Listing
August 2002

Smac is required for cytochrome c-induced apoptosis in prostate cancer LNCaP cells.

Cancer Res 2002 Jan;62(1):18-23

Department of Microbiology, University of Virginia, Charlottesville, Virginia 22908, USA.

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January 2002