Michael J Reed

Michael J Reed

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Michael J Reed

Publications by authors named "Michael J Reed"

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Correlating thyroid cytology and histopathology: Implications for molecular testing.

Head Neck 2016 07 21;38(7):1104-6. Epub 2016 Feb 21.

Department of Otolaryngology - Head and Neck Surgery, University of Iowa, Iowa City, Iowa.

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http://dx.doi.org/10.1002/hed.24410DOI Listing
July 2016

The In Vitro and In Vivo Activity of the Microtubule Disruptor STX140 Is Mediated by Hif-1 Alpha and CAIX Expression.

Anticancer Res 2015 Oct;35(10):5249-61

Oncology Drug Discovery and Women's Health Group, Faculty of Medicine, Imperial College London, St Mary's Hospital, London, U.K. Centre for Endocrinology, Diabetes, and Metabolism, School of Clinical and Experimental Medicine, University of Birmingham, Birmingham, U.K.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4597367PMC
October 2015

STX2171, a 17β-hydroxysteroid dehydrogenase type 3 inhibitor, is efficacious in vivo in a novel hormone-dependent prostate cancer model.

Endocr Relat Cancer 2013 Feb 18;20(1):53-64. Epub 2013 Feb 18.

Oncology Drug Discovery and Women's Health Group, Division of Diabetes, Endocrinology and Metabolism, and Sterix Ltd., Imperial College London, UK.

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https://erc.bioscientifica.com/view/journals/erc/20/1/53.xml
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http://dx.doi.org/10.1530/ERC-12-0231DOI Listing
February 2013

The role of women in dental education: monitoring the pipeline to leadership.

J Dent Educ 2012 Nov;76(11):1427-36

Department of Oral Biology, School of Dentistry, University of Missouri-Kansas City, 650 E. 25 Street, Kansas City, MO 64108, USA.

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http://www.jdentaled.org/content/76/11/1427.full.pdf
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November 2012

Chimeric microtubule disruptors.

Chem Commun (Camb) 2010 May 20;46(17):2907-9. Epub 2010 Mar 20.

Medicinal Chemistry & Sterix Ltd., Department of Pharmacy & Pharmacology, University of Bath, Claverton Down, Bath, BA2 7AY, UK.

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http://dx.doi.org/10.1039/c002558eDOI Listing
May 2010

Synthesis, antitubulin, and antiproliferative SAR of analogues of 2-methoxyestradiol-3,17-O,O-bis-sulfamate.

J Med Chem 2010 Apr;53(7):2942-51

Department of Pharmacy and Pharmacology & Sterix Ltd., University of Bath, Claverton Down, Bath BA2 7AY, U.K.

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http://dx.doi.org/10.1021/jm9018806DOI Listing
April 2010

Highly potent first examples of dual aromatase-steroid sulfatase inhibitors based on a biphenyl template.

J Med Chem 2010 Mar;53(5):2155-70

Medicinal Chemistry, Department of Pharmacy and Pharmacology and Sterix Ltd, University of Bath, Claverton Down, Bath BA2 7AY, UK.

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http://dx.doi.org/10.1021/jm901705hDOI Listing
March 2010

Developing dental faculty for the future: ADEA/AAL Institute for Teaching and Learning, 2006-09.

J Dent Educ 2009 Nov;73(11):1320-35

Academy for Academic Leadership, 1870 The Exchange, Suite 100, Atlanta, GA 30339, USA.

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November 2009

STX140 and STX641 cause apoptosis via the intrinsic mitochondrial pathway and down-regulate survivin and XIAP expression in ovarian and prostate cancer cells.

Anticancer Res 2009 Oct;29(10):3751-7

Oncology Drug Discovery and Women's Health Group, Faculty of Medicine, Imperial College London, St Mary's Hospital, London, W2 1NY, UK.

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October 2009

The design of novel 17beta-hydroxysteroid dehydrogenase type 3 inhibitors.

Mol Cell Endocrinol 2009 Mar 15;301(1-2):259-65. Epub 2008 Aug 15.

Medicinal Chemistry, Department of Pharmacy and Pharmacology and Sterix Ltd., University of Bath, Bath BA2 7AY, UK.

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http://dx.doi.org/10.1016/j.mce.2008.08.005DOI Listing
March 2009

Development of hormone-dependent prostate cancer models for the evaluation of inhibitors of 17beta-hydroxysteroid dehydrogenase type 3.

Mol Cell Endocrinol 2009 Mar 22;301(1-2):251-8. Epub 2008 Aug 22.

Oncology Drug Discovery & Women's Health Group, Department of Endocrinology & Metabolic Medicine, & Sterix Ltd., Imperial College London, London W2 1NY, UK.

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http://dx.doi.org/10.1016/j.mce.2008.08.014DOI Listing
March 2009

The development of steroid sulfatase inhibitors for hormone-dependent cancer therapy.

Ann N Y Acad Sci 2009 Feb;1155:80-7

Endocrinology and Metabolic Medicine and Sterix Ltd., Imperial College London, St. Mary's Hospital, London, W2 1NY, United Kingdom.

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http://dx.doi.org/10.1111/j.1749-6632.2008.03677.xDOI Listing
February 2009

Effects of C-17 heterocyclic substituents on the anticancer activity of 2-ethylestra-1,3,5(10)-triene-3-O-sulfamates: synthesis, in vitro evaluation and computational modelling.

Org Biomol Chem 2008 Nov 22;6(22):4108-19. Epub 2008 Sep 22.

Medicinal Chemistry, Department of Pharmacy and Pharmacology & Sterix Ltd, University of Bath, Claverton Down, Bath, UK BA2 7AY.

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http://dx.doi.org/10.1039/b810300cDOI Listing
November 2008

Recent developments of steroid sulfatase inhibitors as anti-cancer agents.

Anticancer Agents Med Chem 2008 Oct;8(7):732-8

Endocrinology and Metabolic Medicine and Sterix Ltd., Imperial College London, St Mary's Hospital, London, W2 1NY, UK.

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October 2008

Efficacy of three potent steroid sulfatase inhibitors: pre-clinical investigations for their use in the treatment of hormone-dependent breast cancer.

Breast Cancer Res Treat 2008 Sep 4;111(1):129-38. Epub 2007 Oct 4.

Department of Endocrinology and Metabolic Medicine and Sterix Ltd, Imperial College Faculty of Medicine, St Mary's Hospital, London, W2 1NY, UK.

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http://dx.doi.org/10.1007/s10549-007-9769-3DOI Listing
September 2008

2-MeOE2bisMATE and 2-EtE2bisMATE induce cell cycle arrest and apoptosis in breast cancer xenografts as shown by a novel ex vivo technique.

Breast Cancer Res Treat 2008 Sep 24;111(2):251-60. Epub 2007 Oct 24.

Faculty of Medicine, Imperial College London, St. Mary's Hospital, London, W2 1NY, UK.

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http://link.springer.com/10.1007/s10549-007-9791-5
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http://dx.doi.org/10.1007/s10549-007-9791-5DOI Listing
September 2008

Design and validation of specific inhibitors of 17beta-hydroxysteroid dehydrogenases for therapeutic application in breast and prostate cancer, and in endometriosis.

Endocr Relat Cancer 2008 Sep 9;15(3):665-92. Epub 2008 Jun 9.

Department of Endocrinology and Metabolic Medicine, Imperial College, London, London W2 1NY, UK.

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http://dx.doi.org/10.1677/ERC-08-0042DOI Listing
September 2008

The use of steroid sulfatase inhibitors as a novel therapeutic strategy against hormone-dependent endometrial cancer.

Endocrinology 2008 Aug 1;149(8):4035-42. Epub 2008 May 1.

Endocrinology and Metabolic Medicine, Faculty of Medicine, Imperial College London, St. Mary's Hospital, London W2 1NY, United Kingdom.

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https://academic.oup.com/endo/article-lookup/doi/10.1210/en.
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http://dx.doi.org/10.1210/en.2008-0223DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2488239PMC
August 2008

Chiral aromatase and dual aromatase-steroid sulfatase inhibitors from the letrozole template: synthesis, absolute configuration, and in vitro activity.

J Med Chem 2008 Jul 1;51(14):4226-38. Epub 2008 Jul 1.

Medicinal Chemistry, Department of Pharmacy and Pharmacology and Sterix Ltd., University of Bath, Claverton Down, UK.

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http://dx.doi.org/10.1021/jm800168sDOI Listing
July 2008

A comparison of two orally bioavailable anti-cancer agents, IRC-110160 and STX140.

Anticancer Res 2008 May-Jun;28(3A):1483-91

Endocrinology and Metabolic Medicine and Sterix Ltd., Faculty of Medicine, Imperial College London, St. Mary's Hospital, London W2 1NY, UK.

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July 2008

A new micronized formulation of 2-methoxyestradiol-bis-sulfamate (STX140) is therapeutically potent against breast cancer.

Anticancer Res 2008 Mar-Apr;28(2A):577-81

Endocrinology and Metabolic Medicine and Sterix Ltd., Faculty of Medicine, Imperial College London, St. Mary's Hospital, London W2 1NY, UK.

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http://ar.iiarjournals.org/content/28/2A/577.full.pdf
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June 2008

17beta-hydroxysteroid dehydrogenase Type 1, and not Type 12, is a target for endocrine therapy of hormone-dependent breast cancer.

Int J Cancer 2008 May;122(9):1931-40

Department of Endocrinology and Metabolic Medicine and Sterix Ltd., Imperial College London, St. Mary's Hospital, London W2 1NY, United Kingdom.

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http://dx.doi.org/10.1002/ijc.23350DOI Listing
May 2008

Non-steroidal aromatase inhibitors based on a biphenyl scaffold: synthesis, in vitro SAR, and molecular modelling.

ChemMedChem 2008 Apr;3(4):603-18

Medicinal Chemistry, Department of Pharmacy and Pharmacology, and Sterix Ltd. University of Bath, Claverton Down, UK.

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http://dx.doi.org/10.1002/cmdc.200700266DOI Listing
April 2008

Novel inhibitors of 17beta-hydroxysteroid dehydrogenase type 1: templates for design.

Bioorg Med Chem 2008 Apr 7;16(8):4438-56. Epub 2008 Mar 7.

Medicinal Chemistry, Department of Pharmacy and Pharmacology and Sterix Ltd, University of Bath, Claverton Down BA2 7AY, UK.

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http://dx.doi.org/10.1016/j.bmc.2008.02.059DOI Listing
April 2008

Effects of mutations and glycosylations on STS activity: a site-directed mutagenesis study.

Mol Cell Endocrinol 2008 Feb 22;283(1-2):76-82. Epub 2007 Nov 22.

Endocrinology and Metabolic Medicine and Sterix Ltd., Faculty of Medicine, Imperial College London, St. Mary's Hospital, London, W2 1NY, UK.

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http://dx.doi.org/10.1016/j.mce.2007.11.012DOI Listing
February 2008

STX140 is efficacious in vitro and in vivo in taxane-resistant breast carcinoma cells.

Clin Cancer Res 2008 Jan;14(2):597-606

Endocrinology and Metabolic Medicine, Faculty of Medicine, Imperial College London, St Mary's Hospital, London, UK.

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http://dx.doi.org/10.1158/1078-0432.CCR-07-1717DOI Listing
January 2008

Dual aromatase-sulfatase inhibitors based on the anastrozole template: synthesis, in vitro SAR, molecular modelling and in vivo activity.

Org Biomol Chem 2007 Oct;5(20):2940-52

Medicinal Chemistry, Department of Pharmacy and Pharmacology and Sterix Ltd, University of Bath, Claverton Down, Bath, BA2 7AY, UK.

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October 2007

3,17-disubstituted 2-alkylestra-1,3,5(10)-trien-3-ol derivatives: synthesis, in vitro and in vivo anticancer activity.

J Med Chem 2007 Sep 15;50(18):4431-43. Epub 2007 Aug 15.

Medicinal Chemistry, Department of Pharmacy and Pharmacology & Sterix Ltd., University of Bath, Bath BA2 7AY, UK.

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http://dx.doi.org/10.1021/jm070405vDOI Listing
September 2007

Dual aromatase-sulfatase inhibitors based on the anastrozole template: synthesis, in vitro SAR, molecular modelling and in vivo activity.

Org Biomol Chem 2007 Sep 7;5(18):2940-52. Epub 2007 Aug 7.

Medicinal Chemistry, Department of Pharmacy and Pharmacology and Sterix Ltd, University of Bath, Claverton Down, Bath, BA2 7AY, UK.

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http://dx.doi.org/10.1039/b707768hDOI Listing
September 2007

Dual aromatase-steroid sulfatase inhibitors.

J Med Chem 2007 Jul 20;50(15):3540-60. Epub 2007 Jun 20.

Medicinal Chemistry, Department of Pharmacy & Pharmacology and Sterix Limited, University of Bath, Claverton Down, Bath, BA2 7AY, UK.

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http://dx.doi.org/10.1021/jm061462bDOI Listing
July 2007

Cytokines in human breast cyst fluid.

J Steroid Biochem Mol Biol 2007 May 23;104(3-5):241-5. Epub 2007 Mar 23.

Endocrinology and Metabolic Medicine and Sterix Ltd., Imperial College, Faculty of Medicine, St. Mary's Hospital, London W2 1NY, UK.

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http://dx.doi.org/10.1016/j.jsbmb.2007.03.021DOI Listing
May 2007

Novel non-steroidal inhibitors of human 11beta-hydroxysteroid dehydrogenase type 1.

J Steroid Biochem Mol Biol 2007 May 23;104(3-5):123-9. Epub 2007 Mar 23.

Medicinal Chemistry, Department of Pharmacy and Pharmacology and Sterix Ltd., University of Bath, Bath BA2 7AY, UK.

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https://linkinghub.elsevier.com/retrieve/pii/S09600760070007
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http://dx.doi.org/10.1016/j.jsbmb.2007.03.023DOI Listing
May 2007

Inhibition of human and rat 11beta-hydroxysteroid dehydrogenase type 1 by 18beta-glycyrrhetinic acid derivatives.

J Steroid Biochem Mol Biol 2007 May 23;104(3-5):312-20. Epub 2007 Mar 23.

Medicinal Chemistry, Department of Pharmacy and Pharmacology and Sterix Ltd., University of Bath, Bath BA2 7AY, UK.

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http://linkinghub.elsevier.com/retrieve/pii/S096007600700067
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http://dx.doi.org/10.1016/j.jsbmb.2007.03.019DOI Listing
May 2007

Steroid sulfatase: a new target for the endocrine therapy of breast cancer.

Oncologist 2007 Apr;12(4):370-4

Endocrinology and Metabolic Medicine, Imperial College, St. Mary's Hospital, London, United Kingdom.

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http://dx.doi.org/10.1634/theoncologist.12-4-370DOI Listing
April 2007

In vivo efficacy of STX213, a second-generation steroid sulfatase inhibitor, for hormone-dependent breast cancer therapy.

Clin Cancer Res 2006 Sep;12(18):5543-9

Department of Endocrinology and Metabolic Medicine and Sterix Ltd., Imperial College Faculty of Medicine, St. Mary's Hospital, London, United Kingdom.

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http://dx.doi.org/10.1158/1078-0432.CCR-06-0632DOI Listing
September 2006

Lack of aromatisation of the 3-keto-4-ene metabolite of tibolone to an estrogenic derivative.

Steroids 2006 Jul 18;71(7):639-46. Epub 2006 May 18.

Endocrinology and Metabolic Medicine, Faculty of Medicine, Imperial College, St. Mary's Hospital, London W2 1NY, UK.

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http://linkinghub.elsevier.com/retrieve/pii/S0039128X0600080
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http://dx.doi.org/10.1016/j.steroids.2006.03.006DOI Listing
July 2006

Focused libraries of 16-substituted estrone derivatives and modified e-ring steroids: inhibitors of 17beta-hydroxysteroid dehydrogenase type 1.

ChemMedChem 2006 Apr;1(4):464-81

Medicinal Chemistry, Department of Pharmacy and Pharmacology and Sterix Ltd., University of Bath, Claverton Down, Bath, and St. Mary's Hospital, London, UK.

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http://dx.doi.org/10.1002/cmdc.200500087DOI Listing
April 2006

Benzothiazole derivatives as novel inhibitors of human 11beta-hydroxysteroid dehydrogenase type 1.

Mol Cell Endocrinol 2006 Mar 1;248(1-2):214-7. Epub 2005 Dec 1.

Medicinal Chemistry, Department of Pharmacy and Pharmacology and Sterix Ltd., University of Bath, Bath BA2 7AY, UK.

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http://linkinghub.elsevier.com/retrieve/pii/S030372070500394
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http://dx.doi.org/10.1016/j.mce.2005.10.022DOI Listing
March 2006

Novel, potent inhibitors of 17beta-hydroxysteroid dehydrogenase type 1.

Mol Cell Endocrinol 2006 Mar 7;248(1-2):204-7. Epub 2005 Dec 7.

Medicinal Chemistry, Department of Pharmacy and Pharmacology and Sterix Ltd., University of Bath, Claverton Down BA2 7AY, UK.

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https://linkinghub.elsevier.com/retrieve/pii/S03037207050039
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http://dx.doi.org/10.1016/j.mce.2005.10.021DOI Listing
March 2006

17Beta-hydroxysteroid dehydrogenase Type 1 and Type 2: association between mRNA expression and activity in cell lines.

Mol Cell Endocrinol 2006 Mar 21;248(1-2):246-9. Epub 2006 Feb 21.

Endocrinology and Metabolic Medicine and Sterix Ltd., Imperial College, St. Mary's Hospital, London W2 1NY, UK.

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http://dx.doi.org/10.1016/j.mce.2006.01.011DOI Listing
March 2006

Inhibition of MDA-MB-231 cell cycle progression and cell proliferation by C-2-substituted oestradiol mono- and bis-3-O-sulphamates.

Int J Cancer 2005 Oct;117(1):150-9

Endocrinology and Metabolic Medicine and Sterix Ltd., Faculty of Medicine, Imperial College, St. Mary's Hospital, London, United Kingdom.

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http://dx.doi.org/10.1002/ijc.21066DOI Listing
October 2005

E-ring modified steroids as novel potent inhibitors of 17beta-hydroxysteroid dehydrogenase type 1.

J Med Chem 2005 Sep;48(18):5749-70

Medicinal Chemistry, Department of Pharmacy and Pharmacology and Sterix Ltd., University of Bath, Claverton Down BA2 7AY, U.K.

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http://dx.doi.org/10.1021/jm050348aDOI Listing
September 2005

A-ring-substituted estrogen-3-O-sulfamates: potent multitargeted anticancer agents.

J Med Chem 2005 Aug;48(16):5243-56

Medicinal Chemistry, Department of Pharmacy and Pharmacology, University of Bath, Bath BA2 7AY, U.K.

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http://dx.doi.org/10.1021/jm050066aDOI Listing
August 2005

First crystal structures of human carbonic anhydrase II in complex with dual aromatase-steroid sulfatase inhibitors.

Biochemistry 2005 May;44(18):6858-66

Medicinal Chemistry, Department of Pharmacy and Pharmacology, University of Bath, Claverton Down, Bath BA2 7AY, United Kingdom.

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http://dx.doi.org/10.1021/bi047692eDOI Listing
May 2005

Novel and potent 17beta-hydroxysteroid dehydrogenase type 1 inhibitors.

J Med Chem 2005 Apr;48(8):2759-62

Medicinal Chemistry, Department of Pharmacy and Pharmacology and Sterix Ltd., University of Bath, Claverton Down, Bath, BA2 7AY, U.K.

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https://pubs.acs.org/doi/10.1021/jm049045r
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http://dx.doi.org/10.1021/jm049045rDOI Listing
April 2005

A letrozole-based dual aromatase-sulphatase inhibitor with in vivo activity.

J Steroid Biochem Mol Biol 2005 Feb 5;94(1-3):123-30. Epub 2005 Feb 5.

Medicinal Chemistry, Department of Pharmacy and Pharmacology and Sterix Ltd, University of Bath, Claverton Down, Bath, England BA2 7AY, UK.

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http://dx.doi.org/10.1016/j.jsbmb.2004.12.028DOI Listing
February 2005

Anti-cancer activities of novel D-ring modified 2-substituted estrogen-3-O-sulfamates.

J Steroid Biochem Mol Biol 2005 Feb 24;94(1-3):239-51. Epub 2005 Feb 24.

Medicinal Chemistry, Department of Pharmacy and Pharmacology and Sterix Ltd., University of Bath, Claverton Down, Bath BA2 7AY, UK.

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http://dx.doi.org/10.1016/j.jsbmb.2005.01.005DOI Listing
February 2005

The role of steroid sulphatase in regulating the oestrogenicity of oestrogen sulphamates.

Biochem Biophys Res Commun 2004 Sep;322(1):217-22

Endocrinology and Metabolic Medicine and Sterix Ltd, Faculty of Medicine, Imperial College, St. Mary's Hospital, London W2 1NY, UK.

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http://dx.doi.org/10.1016/j.bbrc.2004.07.108DOI Listing
September 2004

Novel 18beta-glycyrrhetinic acid analogues as potent and selective inhibitors of 11beta-hydroxysteroid dehydrogenases.

Bioorg Med Chem 2004 Aug;12(16):4439-57

Medicinal Chemistry, Department of Pharmacy and Pharmacology and Sterix Ltd, University of Bath, Bath BA2 7AY, UK.

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http://dx.doi.org/10.1016/j.bmc.2004.06.008DOI Listing
August 2004

Tibolone: a selective tissue estrogenic activity regulator (STEAR).

Maturitas 2004 Aug;48 Suppl 1:S4-6

Endocrinology and Metabolic Medicine, Faculty of Medicine, Imperial College, St Mary's Hospital, London W2 1NY, UK.

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http://linkinghub.elsevier.com/retrieve/pii/S037851220400109
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http://dx.doi.org/10.1016/j.maturitas.2004.02.013DOI Listing
August 2004

2-Alkylsulfanyl estrogen derivatives: synthesis of a novel class of multi-targeted anti-tumour agents.

Bioorg Med Chem Lett 2004 Jun;14(12):3135-8

Medicinal Chemistry, Department of Pharmacy and Pharmacology and Sterix Ltd, University of Bath, Bath BA2 7AY, UK.

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http://dx.doi.org/10.1016/j.bmcl.2004.04.027DOI Listing
June 2004

A novel 18 beta-glycyrrhetinic acid analogue as a potent and selective inhibitor of 11 beta-hydroxysteroid dehydrogenase 2.

Bioorg Med Chem Lett 2004 Jun;14(12):3263-7

Medicinal Chemistry, Department of Pharmacy and Pharmacology and Sterix Ltd, University of Bath, Bath BA2 7AY, UK.

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http://dx.doi.org/10.1016/j.bmcl.2004.03.107DOI Listing
June 2004

Synthesis, in vitro and in vivo activity of benzophenone-based inhibitors of steroid sulfatase.

Bioorg Med Chem 2004 May;12(10):2759-72

Medicinal Chemistry, Department of Pharmacy and Pharmacology and Sterix Ltd., University of Bath, Bath BA2 7AY, UK.

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https://linkinghub.elsevier.com/retrieve/pii/S09680896040016
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http://dx.doi.org/10.1016/j.bmc.2004.02.040DOI Listing
May 2004

Inhibition of in vitro angiogenesis by 2-methoxy- and 2-ethyl-estrogen sulfamates.

Int J Cancer 2004 Apr;109(4):533-40

Endocrinology and Metabolic Medicine and Sterix Ltd, Faculty of Medicine, Imperial College, St. Mary's Hospital, London, United Kingdom.

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http://dx.doi.org/10.1002/ijc.20045DOI Listing
April 2004

2-difluoromethyloestrone 3-O-sulphamate, a highly potent steroid sulphatase inhibitor.

Biochem Biophys Res Commun 2004 Apr;317(1):169-75

Medicinal Chemistry, Department of Pharmacy and Pharmacology and Sterix Ltd, University of Bath, Bath BA2 7AY, UK.

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http://dx.doi.org/10.1016/j.bbrc.2004.03.023DOI Listing
April 2004

Addressing dental workforce issues in Missouri and Kansas: one school's initiative.

J Dent Educ 2003 Aug;67(8):902-8

School of Dentistry, University of Missouri-Kansas City, 64108, USA.

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August 2003

First dual aromatase-steroid sulfatase inhibitors.

J Med Chem 2003 Jul;46(15):3193-6

Medicinal Chemistry, Department of Pharmacy and Pharmacology and Sterix Ltd., University of Bath, Claverton Down, Bath BA2 7AY, UK.

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http://dx.doi.org/10.1021/jm034033bDOI Listing
July 2003

D-ring modified estrone derivatives as novel potent inhibitors of steroid sulfatase.

Bioorg Med Chem 2003 Apr;11(8):1685-700

Medicinal Chemistry, Department of Pharmacy and Pharmacology and Sterix Ltd., University of Bath, Claverton Down, Bath BA2 7AY, UK.

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http://dx.doi.org/10.1016/s0968-0896(03)00042-7DOI Listing
April 2003

Docking studies of sulphamate inhibitors of estrone sulphatase in human carbonic anhydrase II.

Bioorg Med Chem Lett 2003 Mar;13(5):863-5

Medicinal Chemistry, Department of Pharmacy and Pharmacology and Sterix Ltd, University of Bath, Bath BA2 7AY, UK.

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http://dx.doi.org/10.1016/s0960-894x(03)00009-xDOI Listing
March 2003

The effects of 2-substituted oestrogen sulphamates on the growth of prostate and ovarian cancer cells.

J Steroid Biochem Mol Biol 2003 Feb;84(2-3):317-25

Endocrinology and Metabolic Medicine, Faculty of Medicine and Sterix Ltd., Imperial College, St. Mary's Hospital, London W2 1NY, UK.

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http://dx.doi.org/10.1016/s0960-0760(03)00045-1DOI Listing
February 2003

Development of a sensitive high-performance liquid chromatography method for the detection of 667 COUMATE in vivo.

J Steroid Biochem Mol Biol 2003 Feb;84(2-3):337-42

Endocrinology and Metabolic Medicine and Sterix Ltd., Faculty of Medicine, Imperial College, St. Mary's Hospital, London W2 1NY, UK.

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http://dx.doi.org/10.1016/s0960-0760(03)00047-5DOI Listing
February 2003

Novel D-ring modified steroid derivatives as potent, non-estrogenic, steroid sulfatase inhibitors with in vivo activity.

J Steroid Biochem Mol Biol 2003 Feb;84(2-3):343-9

Department of Pharmacy and Pharmacology, University of Bath, Claverton Down, UK.

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http://dx.doi.org/10.1016/s0960-0760(03)00048-7DOI Listing
February 2003

Inhibition of MCF-7 breast cancer cell proliferation and in vivo steroid sulphatase activity by 2-methoxyoestradiol-bis-sulphamate.

J Steroid Biochem Mol Biol 2003 Feb;84(2-3):351-8

Endocrinology and Metabolic Medicine, Faculty of Medicine and Sterix Ltd., Imperial College, St. Mary's Hospital, London W2 1NY, UK.

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http://dx.doi.org/10.1016/s0960-0760(03)00049-9DOI Listing
February 2003

Estrone 3-sulfate mimics, inhibitors of estrone sulfatase activity: homology model construction and docking studies.

Biochemistry 2002 Dec;41(50):14801-14

Medicinal Chemistry, Department of Pharmacy and Pharmacology, University of Bath, Claverton Down, UK.

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http://dx.doi.org/10.1021/bi020543gDOI Listing
December 2002

Regulation of estrogen synthesis in postmenopausal women.

Steroids 2002 Nov;67(12):979-83

Endocrinology and Metabolic Medicine, Imperial College School of Medicine, St Mary's Hospital, W2 1NY, London, UK.

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November 2002

The role of cytokines in regulating estrogen synthesis: implications for the etiology of breast cancer.

Breast Cancer Res 2002 14;4(2):65-9. Epub 2002 Jan 14.

Faculty of Medicine, Imperial College, St Mary's Hospital, London, UK.

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May 2002