Michael J Gough

Michael J Gough

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Michael J Gough

Michael J Gough

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Radiofrequency Venous Ablation: Not Simple and Not Always Effective!

Authors:
Michael J Gough

Eur J Vasc Endovasc Surg 2019 Sep 21;58(3):409. Epub 2019 May 21.

University of Leeds, Leeds, UK. Electronic address:

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http://dx.doi.org/10.1016/j.ejvs.2019.04.010DOI Listing
September 2019

Implantable biomaterials to provide local immunotherapy following surgical resection.

Oncotarget 2018 Dec 28;9(102):37612-37613. Epub 2018 Dec 28.

Earle A. Chiles Research Institute, Providence Cancer Institute, Providence Portland Medical Center, Portland, OR, USA.

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http://dx.doi.org/10.18632/oncotarget.26487DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6340878PMC
December 2018

Association of Immunologic Markers With Survival in Upfront Resectable Pancreatic Cancer.

JAMA Surg 2018 11;153(11):1055-1057

Integrated Therapies Laboratory, Earle A. Chiles Research Institute, Providence Portland Medical Center, Portland, Oregon.

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http://dx.doi.org/10.1001/jamasurg.2018.1757DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6583701PMC
November 2018

Role of the immunosuppressive microenvironment in immunotherapy.

Adv Radiat Oncol 2018 Oct-Dec;3(4):520-526. Epub 2018 Oct 23.

Earl A. Chiles Research Institute, Providence Portland Medical Center, Portland, Oregon.

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https://linkinghub.elsevier.com/retrieve/pii/S24521094183015
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http://dx.doi.org/10.1016/j.adro.2018.08.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6200899PMC
October 2018

Activating the Nucleic Acid-Sensing Machinery for Anticancer Immunity.

Int Rev Cell Mol Biol 2019 2;344:173-214. Epub 2018 Oct 2.

Earle A. Chiles Research Institute, Robert W. Franz Cancer Center, Providence Portland Medical Center, Portland, OR, United States. Electronic address:

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http://dx.doi.org/10.1016/bs.ircmb.2018.08.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6754183PMC
October 2018

Amplifying IFN-γ Signaling in Dendritic Cells by CD11c-Specific Loss of SOCS1 Increases Innate Immunity to Infection while Decreasing Adaptive Immunity.

J Immunol 2018 01 17;200(1):177-185. Epub 2017 Nov 17.

Earle A. Chiles Research Institute, Robert W. Franz Cancer Center, Providence Portland Medical Center, Portland, OR 97213; and

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http://dx.doi.org/10.4049/jimmunol.1700909DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5736417PMC
January 2018

STING expression and response to treatment with STING ligands in premalignant and malignant disease.

PLoS One 2017 14;12(11):e0187532. Epub 2017 Nov 14.

Earle A. Chiles Research Institute, Robert W. Franz Cancer Center, Providence Portland Medical Center, Portland, OR, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0187532PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5685615PMC
December 2017

Perceptions About the Present and Future of Surgical Simulation: A National Study of Mixed Qualitative and Quantitative Methodology.

J Surg Educ 2017 Jan - Feb;74(1):108-116. Epub 2016 Sep 8.

School of Surgery, Health Education Yorkshire and the Humber, Leeds, West Yorkshire, United Kingdom.

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http://dx.doi.org/10.1016/j.jsurg.2016.07.011DOI Listing
November 2017

Timing of PD-1 Blockade Is Critical to Effective Combination Immunotherapy with Anti-OX40.

Clin Cancer Res 2017 Oct 28;23(20):6165-6177. Epub 2017 Aug 28.

Earle A. Chiles Research Institute, Robert W. Franz Cancer Research Center, Providence Portland Cancer Center, Portland, Oregon.

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http://dx.doi.org/10.1158/1078-0432.CCR-16-2677DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5641261PMC
October 2017

Stimulating Innate Immunity to Enhance Radiation Therapy-Induced Tumor Control.

Int J Radiat Oncol Biol Phys 2017 10 19;99(2):362-373. Epub 2017 Apr 19.

Earle A. Chiles Research Institute, Providence Cancer Center, Portland, Oregon. Electronic address:

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http://dx.doi.org/10.1016/j.ijrobp.2017.04.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5604475PMC
October 2017

Optimizing Timing of Immunotherapy Improves Control of Tumors by Hypofractionated Radiation Therapy.

PLoS One 2016 9;11(6):e0157164. Epub 2016 Jun 9.

Earle A. Chiles Research Institute, Robert W. Franz Cancer Center, Providence Portland Medical Center, 4805 NE Glisan St, Portland, OR, 97213, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0157164PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4900555PMC
July 2017

Programmed cell death-1 blockade enhances response to stereotactic radiation in an orthotopic murine model of hepatocellular carcinoma.

Hepatol Res 2017 Jun 22;47(7):702-714. Epub 2016 Sep 22.

Earle A. Chiles Research Institute, Providence Cancer Center, Portland, Oregon.

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http://dx.doi.org/10.1111/hepr.12789DOI Listing
June 2017

Erratum to 'Cytoreductive surgery for head and neck squamous cell carcinoma in the new age of immunotherapy' [Oral Oncol. 61 (2016) 166-176].

Oral Oncol 2017 03 12;66:e3. Epub 2017 Feb 12.

Earle A. Chiles Research Institute at Providence Cancer Center, 4805 NE Glisan St. Suite 2N35, Portland, OR 97213, United States.

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http://dx.doi.org/10.1016/j.oraloncology.2017.02.001DOI Listing
March 2017

Cytoreductive surgery for head and neck squamous cell carcinoma in the new age of immunotherapy.

Oral Oncol 2016 10 7;61:166-76. Epub 2016 Sep 7.

Earle A. Chiles Research Institute at Providence Cancer Center, 4805 NE Glisan St. Suite 2N35, Portland, OR 97213, United States.

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http://dx.doi.org/10.1016/j.oraloncology.2016.08.020DOI Listing
October 2016

Comparing equals when evaluating immunotherapy with different doses and fractions of radiation therapy.

Immunotherapy 2015 13;7(8):847-9. Epub 2015 Aug 13.

Earle A Chiles Research Institute, Robert W Franz Cancer Center, Providence Portland Medical Center, 4805 NE Glisan St, Portland, OR 97213, USA.

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https://www.futuremedicine.com/doi/10.2217/IMT.15.58
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http://dx.doi.org/10.2217/IMT.15.58DOI Listing
June 2016

Radiotherapy Combined with Novel STING-Targeting Oligonucleotides Results in Regression of Established Tumors.

Cancer Res 2016 Jan 13;76(1):50-61. Epub 2015 Nov 13.

Earle A. Chiles Research Institute, Robert W. Franz Cancer Center, Providence Portland Medical Center, Portland, Oregon.

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http://dx.doi.org/10.1158/0008-5472.CAN-14-3619DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4703500PMC
January 2016

OX40 signaling in head and neck squamous cell carcinoma: Overcoming immunosuppression in the tumor microenvironment.

Oral Oncol 2016 Jan 21;52:1-10. Epub 2015 Nov 21.

Robert W. Franz Cancer Research Center in the Earle A. Chiles Research Institute at the Providence Cancer Center, 4805 NE Glisan St. Suite 2N35, Portland, OR 97213, United States.

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http://dx.doi.org/10.1016/j.oraloncology.2015.11.009DOI Listing
January 2016

Developing an Immunotherapy Strategy for the Effective Treatment of Oral, Head and Neck Squamous Cell Carcinoma.

J Oral Maxillofac Surg 2015 Dec;73(12 Suppl):S107-15

Chief, Laboratory of Molecular and Tumor Immunology, Robert W. Franz Cancer Research Center in the Earle A. Chiles Research Institute at Providence Cancer Center, Portland, OR.

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http://dx.doi.org/10.1016/j.joms.2015.05.026DOI Listing
December 2015

Attitudes towards the surgical safety checklist and factors associated with its use: A global survey of frontline medical professionals.

Ann Med Surg (Lond) 2015 Jun 20;4(2):119-23. Epub 2015 Apr 20.

Yorkshire School of Surgery, The Department for Postgraduate Medical & Dental Education, Willow Terrace Road, University of Leeds, Leeds LS2 9JT, UK.

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http://dx.doi.org/10.1016/j.amsu.2015.04.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4421109PMC
June 2015

Tumor immune remodeling by TGFβ inhibition improves the efficacy of radiation therapy.

Oncoimmunology 2015 Mar 14;4(3):e955696. Epub 2014 Sep 14.

Earle A. Chiles Research Institute; Providence Portland Medical Center ; Portland, OR, USA ; The Oregon Clinic ; Portland, OR, USA.

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http://dx.doi.org/10.4161/21624011.2014.955696DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4404800PMC
March 2015

TGFβ inhibition prior to hypofractionated radiation enhances efficacy in preclinical models.

Cancer Immunol Res 2014 Oct 21;2(10):1011-22. Epub 2014 Jul 21.

Earle A. Chiles Research Institute, Providence Portland Medical Center, Portland, Oregon. The Oregon Clinic, Portland, Oregon.

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http://dx.doi.org/10.1158/2326-6066.CIR-13-0207DOI Listing
October 2014

Expression of arginase I in myeloid cells limits control of residual disease after radiation therapy of tumors in mice.

Radiat Res 2014 Aug 3;182(2):182-90. Epub 2014 Jul 3.

a  Earle A. Chiles Research Institute, Robert W. Franz Cancer Center, Providence Portland Medical Center, Portland, Oregon;

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http://dx.doi.org/10.1667/RR13493.1DOI Listing
August 2014

The impact of the myeloid response to radiation therapy.

Clin Dev Immunol 2013 7;2013:281958. Epub 2013 Apr 7.

Earle A. Chiles Research Institute, Robert W. Franz Cancer Center, Providence Portland Medical Center, 4805 NE Glisan, Portland, OR 97213, USA.

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http://www.hindawi.com/journals/jir/2013/281958/
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http://dx.doi.org/10.1155/2013/281958DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3638700PMC
July 2013

The ataxia telangiectasia mutated kinase pathway regulates IL-23 expression by human dendritic cells.

J Immunol 2013 Apr 4;190(7):3246-55. Epub 2013 Mar 4.

Host:Tumour Interactions Group, Academic Unit of Clinical Oncology, University of Nottingham, Nottingham NG5 1PB, United Kingdom.

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http://dx.doi.org/10.4049/jimmunol.1201484DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3672964PMC
April 2013

Expression of NF-κB p50 in tumor stroma limits the control of tumors by radiation therapy.

PLoS One 2012 28;7(6):e39295. Epub 2012 Jun 28.

Earle A Chiles Research Institute, Providence Portland Medical Center, Portland, Oregon, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0039295PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3386283PMC
March 2013

Children's surgery: a national survey of consultant clinical practice.

BMJ Open 2012 17;2(5). Epub 2012 Oct 17.

Nuffield Department of Anaesthesia, Oxford University Hospitals NHS Trust, Oxford, UK.

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http://dx.doi.org/10.1136/bmjopen-2012-001639DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3488724PMC
October 2012

Targeting macrophages in the tumour environment to enhance the efficacy of αOX40 therapy.

Immunology 2012 Aug;136(4):437-47

Robert W. Franz Cancer Center, Earle A. Chiles Research Institute, Providence Portland Medical Center, Portland, OR 97213 USA.

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http://dx.doi.org/10.1111/j.1365-2567.2012.03600.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3401982PMC
August 2012

Preprocedural imaging strategies in symptomatic carotid artery stenosis.

Authors:
Michael J Gough

J Vasc Surg 2011 Oct 25;54(4):1215-8. Epub 2011 Aug 25.

Leeds Vascular Institute, The General Infirmary at Leeds, Leeds, United Kingdom.

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http://linkinghub.elsevier.com/retrieve/pii/S074152141101346
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http://dx.doi.org/10.1016/j.jvs.2011.05.101DOI Listing
October 2011

OX40 (CD134) and OX40L.

Adv Exp Med Biol 2009 ;647:94-107

Robert W. Franz Cancer Center, Earle A. Chiles Research Institute, Providence Portland Medical Center, Portland, OR, 97213, USA.

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http://dx.doi.org/10.1007/978-0-387-89520-8_6DOI Listing
June 2010

Combination approaches to immunotherapy: the radiotherapy example.

Immunotherapy 2009 Nov;1(6):1025-37

Robert W Franz Cancer Center, Earle A Chiles Research Institute, Providence Portland Medical Center, Portland, OR 97213, USA.

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http://dx.doi.org/10.2217/imt.09.64DOI Listing
November 2009

Ligation of the OX40 co-stimulatory receptor reverses self-Ag and tumor-induced CD8 T-cell anergy in vivo.

Eur J Immunol 2009 Aug;39(8):2184-94

Earle A. Chiles Research Institute, Robert W. Franz Cancer Research Center, Providence Portland Medical Center, Portland, OR 97213, USA.

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http://dx.doi.org/10.1002/eji.200939348DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3509800PMC
August 2009

Carotid artery stenosis: accuracy of noninvasive tests--individual patient data meta-analysis.

Radiology 2009 May 10;251(2):493-502. Epub 2009 Mar 10.

Division of Clinical Neurosciences, University of Edinburgh, Western General Hospital, Crewe Rd, Edinburgh EH42XU, Scotland.

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http://dx.doi.org/10.1148/radiol.2512080284DOI Listing
May 2009

OX40 agonist therapy enhances CD8 infiltration and decreases immune suppression in the tumor.

Cancer Res 2008 Jul;68(13):5206-15

Robert W Franz Cancer Center, Earle A Chiles Research Institute, Providence Portland Medical Center, Portland, Oregon 97213, USA.

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http://cancerres.aacrjournals.org/content/68/13/5206.full.pd
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http://cancerres.aacrjournals.org/cgi/doi/10.1158/0008-5472.
Publisher Site
http://dx.doi.org/10.1158/0008-5472.CAN-07-6484DOI Listing
July 2008

High resolution magnetic resonance imaging of excised atherosclerotic carotid tissue: the effects of specimen temperature on image contrast.

J Cardiovasc Magn Reson 2007 ;9(6):915-20

Academic Unit of Medical Physics, Department of Histopathology, University of Leeds, Leeds, United Kingdom.

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http://dx.doi.org/10.1080/10976640701693790DOI Listing
February 2008

Defects in the acquisition of CD8 T cell effector function after priming with tumor or soluble antigen can be overcome by the addition of an OX40 agonist.

J Immunol 2007 Dec;179(11):7244-53

Earle A Chiles Research Institute, Robert W Franz Cancer Research Center, Providence Portland Medical Center, Portland, OR 97213, USA.

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http://dx.doi.org/10.4049/jimmunol.179.11.7244DOI Listing
December 2007

Multiple peripheral pneumococcal mycotic aneurysms without aortic involvement: a unique case confirmed with the novel use of a molecular diagnostic technique.

J Vasc Surg 2007 Jun;45(6):1253-5

Leeds Vascular Institute, Microbiology Department, Leeds General Infirmary, Leeds, United Kingdom.

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http://dx.doi.org/10.1016/j.jvs.2007.01.039DOI Listing
June 2007

Changes in carotid plaque echomorphology with time since a neurologic event.

J Vasc Surg 2007 Feb;45(2):367-72

Vascular Surgical Unit, The General Infirmary at Leeds, Leeds, United Kingdom.

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http://linkinghub.elsevier.com/retrieve/pii/S074152140601829
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http://dx.doi.org/10.1016/j.jvs.2006.09.048DOI Listing
February 2007

Intratumoral immunotherapy: using the tumour against itself.

Immunology 2005 Jan;114(1):11-22

Molecular Medicine Program, Mayo Clinic, Rochester, MN, USA.

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http://dx.doi.org/10.1111/j.1365-2567.2004.02001.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1782057PMC
January 2005

Minimally invasive treatment for varicose veins: a review of endovenous laser treatment and radiofrequency ablation.

Int J Low Extrem Wounds 2004 Dec;3(4):188-97

The Vascular Surgical Unit, The General Infirmary at Leeds, Leeds, UK.

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http://journals.sagepub.com/doi/10.1177/1534734604272245
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http://dx.doi.org/10.1177/1534734604272245DOI Listing
December 2004

Facets of heat shock protein 70 show immunotherapeutic potential.

Immunology 2003 Sep;110(1):1-9

Immune Regulation Research Group, Department of Biochemistry, Trinity College, Dublin, Ireland.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1783014PMC
http://dx.doi.org/10.1046/j.1365-2567.2003.01725.xDOI Listing
September 2003