Michael J Chao

Michael J Chao

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Michael J Chao

Michael J Chao

Publications by authors named "Michael J Chao"

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Genetic Modification of Huntington Disease Acts Early in the Prediagnosis Phase.

Am J Hum Genet 2018 09 16;103(3):349-357. Epub 2018 Aug 16.

Molecular Neurogenetics Unit, Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA 02114, USA; Medical and Population Genetics Program, the Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Department of Genetics, Harvard Medical School, Boston, MA 02115, USA. Electronic address:

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4524551/
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https://linkinghub.elsevier.com/retrieve/pii/S00029297183024
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http://dx.doi.org/10.1016/j.ajhg.2018.07.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6128248PMC
September 2018

Population-specific genetic modification of Huntington's disease in Venezuela.

PLoS Genet 2018 05 11;14(5):e1007274. Epub 2018 May 11.

Molecular Neurogenetics Unit, Center for Genomic Medicine, Massachusetts General Hospital, Boston, Massachusetts, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.1007274DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5965898PMC
May 2018

Haplotype-based stratification of Huntington's disease.

Eur J Hum Genet 2017 11 23;25(11):1202-1209. Epub 2017 Aug 23.

Molecular Neurogenetics Unit, Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.

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http://dx.doi.org/10.1038/ejhg.2017.125DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5643960PMC
November 2017

A modifier of Huntington's disease onset at the MLH1 locus.

Hum Mol Genet 2017 10;26(19):3859-3867

Molecular Neurogenetics Unit, Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA 02114, USA.

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http://dx.doi.org/10.1093/hmg/ddx286DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6455020PMC
October 2017

Permanent inactivation of Huntington's disease mutation by personalized allele-specific CRISPR/Cas9.

Hum Mol Genet 2016 10;25(20):4566-4576

Molecular Neurogenetics Unit, Center for Human Genetic Research, Massachusetts General Hospital, Boston, MA, USA.

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http://dx.doi.org/10.1093/hmg/ddw286DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6078600PMC
October 2016

Sequence-Level Analysis of the Major European Huntington Disease Haplotype.

Am J Hum Genet 2015 Sep 27;97(3):435-44. Epub 2015 Aug 27.

Center for Human Genetic Research, Massachusetts General Hospital, Boston, MA 02114, USA; Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA; Department of Genetics, Harvard Medical School, Boston, MA 02115, USA.

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http://dx.doi.org/10.1016/j.ajhg.2015.07.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4564985PMC
September 2015

Vitamin D metabolic pathway genes and risk of multiple sclerosis in Canadians.

J Neurol Sci 2011 Jun 26;305(1-2):116-20. Epub 2011 Mar 26.

Wellcome Trust Centre for Human Genetics and Department of Clinical Neurology, University of Oxford, Oxford, UK.

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http://dx.doi.org/10.1016/j.jns.2011.02.032DOI Listing
June 2011

Parent-of-origin effects at the major histocompatibility complex in multiple sclerosis.

Hum Mol Genet 2010 Sep 15;19(18):3679-89. Epub 2010 Jul 15.

Department of Clinical Neurology, John Radcliffe Hospital, University of Oxford, Oxford, UK.

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http://dx.doi.org/10.1093/hmg/ddq282DOI Listing
September 2010

Epistasis among HLA-DRB1, HLA-DQA1, and HLA-DQB1 loci determines multiple sclerosis susceptibility.

Proc Natl Acad Sci U S A 2009 May 20;106(18):7542-7. Epub 2009 Apr 20.

University Department of Clinical Neurology, Third Floor, West Wing, John Radcliffe Hospital, University of Oxford, Oxford OX3 9DU, United Kingdom.

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http://dx.doi.org/10.1073/pnas.0812664106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2678609PMC
May 2009

Epigenetics in multiple sclerosis susceptibility: difference in transgenerational risk localizes to the major histocompatibility complex.

Hum Mol Genet 2009 Jan;18(2):261-6

Department of Clinical Neurology, Level 3 West Wing, John Radcliffe Hospital, University of Oxford, Oxford OX3 7BN, UK.

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https://academic.oup.com/hmg/article-lookup/doi/10.1093/hmg/
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http://dx.doi.org/10.1093/hmg/ddn353DOI Listing
January 2009

Parental transmission of HLA-DRB1*15 in multiple sclerosis.

Hum Genet 2008 Jan 31;122(6):661-3. Epub 2007 Oct 31.

Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.

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http://dx.doi.org/10.1007/s00439-007-0442-zDOI Listing
January 2008

Transmission of class I/II multi-locus MHC haplotypes and multiple sclerosis susceptibility: accounting for linkage disequilibrium.

Hum Mol Genet 2007 Aug 20;16(16):1951-8. Epub 2007 Jun 20.

Department of Clinical Neurology, University of Oxford, John Radcliffe Hospital, Oxford, UK.

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http://dx.doi.org/10.1093/hmg/ddm142DOI Listing
August 2007