Michael Ittmann

Michael Ittmann

UNVERIFIED PROFILE

Are you Michael Ittmann?   Register this Author

Register author
Michael Ittmann

Michael Ittmann

Publications by authors named "Michael Ittmann"

Are you Michael Ittmann?   Register this Author

100Publications

2865Reads

49Profile Views

Targeting the TMPRSS2/ERG fusion mRNA using liposomal nanovectors enhances docetaxel treatment in prostate cancer.

Prostate 2020 Jan 15;80(1):65-73. Epub 2019 Oct 15.

Department of Pathology and Immunology, Baylor College of Medicine, Michael E. DeBakey Department of Veterans Affairs Medical Center, Houston, Texas.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/pros.23918DOI Listing
January 2020

Short-term RANKL exposure initiates a neoplastic transcriptional program in the basal epithelium of the murine salivary gland.

Cytokine 2019 Nov 18;123:154745. Epub 2019 Jun 18.

Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cyto.2019.154745DOI Listing
November 2019

Association of Genetic Ancestry With DNA Methylation Changes in Prostate Cancer Disparity.

Anticancer Res 2019 Nov;39(11):5861-5866

Department of Biochemistry and Molecular Biology Howard University, Washington, DC, U.S.A.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.21873/anticanres.13790DOI Listing
November 2019

ING5 inhibits cancer aggressiveness by inhibiting Akt and activating p53 in prostate cancer.

Cell Biol Int 2019 Sep 2. Epub 2019 Sep 2.

Department of Molecular Biology and Genetics, Erzurum Technical University, Erzurum, 25250, Turkey.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/cbin.11227DOI Listing
September 2019

Comparative analysis of p16 expression among African American and European American prostate cancer patients.

Prostate 2019 Aug 21;79(11):1274-1283. Epub 2019 May 21.

Department of Pathology and Immunology, Michael E. DeBakey VA Medical Center, Baylor College of Medicine, Houston, Texas.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/pros.23833DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6617792PMC
August 2019

Moving Beyond Gleason Scoring.

Arch Pathol Lab Med 2019 May 13;143(5):565-570. Epub 2019 Mar 13.

From the Department of Urology, The Methodist Hospital, Houston, Texas (Dr Miles); the Departments of Pathology & Immunology (Drs Ittmann and Wheeler and Mr Sayeeduddin) and Molecular and Cell Biology (Dr Rowley), Baylor College of Medicine, Houston, Texas; Instituto de Patologia e Investigacion, Asuncion, Paraguay (Dr Cubilla); Biostatistics/Epidemiology/Research Design (BERD) Core, Departments of Internal Medicine (Dr Lee) and Pathology and Laboratory Medicine (Drs Bu, Ding, Gao, and Ayala), University of Texas Health Sciences Center Medical School, Houston.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.5858/arpa.2018-0242-RADOI Listing
May 2019

Spatially Restricted Stromal Wnt Signaling Restrains Prostate Epithelial Progenitor Growth through Direct and Indirect Mechanisms.

Cell Stem Cell 2019 May 11;24(5):753-768.e6. Epub 2019 Apr 11.

Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX 77030, USA; Department of Urology, University of Washington, Seattle, WA 98109, USA; Institute of Stem Cell and Regenerative Medicine, University of Washington, Seattle, WA 98109, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.stem.2019.03.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6548441PMC
May 2019

JNK represses Lkb-deficiency-induced lung squamous cell carcinoma progression.

Nat Commun 2019 05 14;10(1):2148. Epub 2019 May 14.

Reproductive & Developmental Biology Laboratory, National Institute of Environmental Health Sciences (NIEHS), Research Triangle Park (RTP), 27709, NC, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41467-019-09843-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6517592PMC
May 2019

MicroRNAs as prognostic markers in prostate cancer.

Prostate 2019 02 21;79(3):265-271. Epub 2018 Oct 21.

Department of Pathology and Immunology, Baylor College of Medicine, Houston, Texas.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/pros.23731DOI Listing
February 2019

Androgen deprivation promotes neuroendocrine differentiation and angiogenesis through CREB-EZH2-TSP1 pathway in prostate cancers.

Nat Commun 2018 10 4;9(1):4080. Epub 2018 Oct 4.

Texas Therapeutics Institute, Brown Foundation Institute of Molecular Medicine, University of Texas Health Science Center at Houston, Houston, TX 77030, USA.

View Article

Download full-text PDF

Source
http://www.nature.com/articles/s41467-018-06177-2
Publisher Site
http://dx.doi.org/10.1038/s41467-018-06177-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6172226PMC
October 2018

Impact of diet on irinotecan toxicity in mice.

Chem Biol Interact 2018 Aug 18;291:87-94. Epub 2018 Jun 18.

Department of Pharmacological and Pharmaceutical Sciences, University of Houston, Houston, TX, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cbi.2018.06.018DOI Listing
August 2018

TRAF4-mediated ubiquitination of NGF receptor TrkA regulates prostate cancer metastasis.

J Clin Invest 2018 07 18;128(7):3129-3143. Epub 2018 Jun 18.

Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, Texas, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1172/JCI96060DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6026011PMC
July 2018

Anatomy and Histology of the Human and Murine Prostate.

Authors:
Michael Ittmann

Cold Spring Harb Perspect Med 2018 05 1;8(5). Epub 2018 May 1.

Department of Pathology and Immunology, Baylor College of Medicine, Houston, Texas 77030.

View Article

Download full-text PDF

Source
http://perspectivesinmedicine.cshlp.org/lookup/doi/10.1101/c
Publisher Site
http://dx.doi.org/10.1101/cshperspect.a030346DOI Listing
May 2018

Pan-Cancer Molecular Classes Transcending Tumor Lineage Across 32 Cancer Types, Multiple Data Platforms, and over 10,000 Cases.

Clin Cancer Res 2018 05 9;24(9):2182-2193. Epub 2018 Feb 9.

Dan L. Duncan Comprehensive Cancer Center Division of Biostatistics, Baylor College of Medicine, Houston, Texas.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/1078-0432.CCR-17-3378DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5932236PMC
May 2018

Fibroblast growth factor receptor signaling plays a key role in transformation induced by the TMPRSS2/ERG fusion gene and decreased PTEN.

Oncotarget 2018 Mar 12;9(18):14456-14471. Epub 2018 Feb 12.

Deptartment of Pathology & Immunology, Baylor College of Medicine, Houston, Texas 77030, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.18632/oncotarget.24470DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5865682PMC
March 2018

Influence of the neural microenvironment on prostate cancer.

Prostate 2018 Feb 13;78(2):128-139. Epub 2017 Nov 13.

Department of Pathology and Laboratory Medicine, University of Texas Health Sciences Center Medical School, Houston, Texas.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/pros.23454DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5836952PMC
February 2018

Comprehensive Genomic Characterization of Upper Tract Urothelial Carcinoma.

Eur Urol 2017 10 7;72(4):641-649. Epub 2017 Jun 7.

Department of Urology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.eururo.2017.05.048DOI Listing
October 2017

Androgen Receptor Pathway-Independent Prostate Cancer Is Sustained through FGF Signaling.

Cancer Cell 2017 10;32(4):474-489.e6

Department of Medicine, University of Washington, Seattle, WA, USA; Divisions of Human Biology and Clinical Research, Fred Hutchinson Cancer Research Center, Mailstop D4-100, 1100 Fairview Avenue N, Seattle, WA 98109-1024, USA; Department of Urology, University of Washington, 1959 NE Pacific Street, Seattle, WA 98195, USA; Department of Pathology, University of Washington, Seattle, WA, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ccell.2017.09.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5750052PMC
October 2017

miR-33a is a tumor suppressor microRNA that is decreased in prostate cancer.

Oncotarget 2017 Sep 24;8(36):60243-60256. Epub 2017 Jul 24.

Department of Pathology and Immunology and Michael E. DeBakey Department of Veterans Affairs Medical Center, Houston, TX, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.18632/oncotarget.19521DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5601135PMC
September 2017

RET Signaling in Prostate Cancer.

Clin Cancer Res 2017 Aug 10;23(16):4885-4896. Epub 2017 May 10.

Department of Pathology & Immunology, Baylor College of Medicine and Michael E. DeBakey Dept. of Veterans Affairs Medical Center, Houston, Texas.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/1078-0432.CCR-17-0528DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5609835PMC
August 2017

RGS12 Is a Novel Tumor-Suppressor Gene in African American Prostate Cancer That Represses AKT and MNX1 Expression.

Cancer Res 2017 08 13;77(16):4247-4257. Epub 2017 Jun 13.

Department of Pathology and Immunology, Baylor College of Medicine and Michael E. DeBakey Department of Veterans Affairs Medical Center, Houston, Texas.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/0008-5472.CAN-17-0669DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5559317PMC
August 2017

Pan-urologic cancer genomic subtypes that transcend tissue of origin.

Nat Commun 2017 08 4;8(1):199. Epub 2017 Aug 4.

Dan L. Duncan Comprehensive Cancer Center Division of Biostatistics, Baylor College of Medicine, Houston, TX, 77030, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41467-017-00289-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5543131PMC
August 2017

A Pan-Cancer Proteogenomic Atlas of PI3K/AKT/mTOR Pathway Alterations.

Cancer Cell 2017 06 18;31(6):820-832.e3. Epub 2017 May 18.

Dan L. Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, TX 77030, USA; Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA; Department of Medicine, Baylor College of Medicine, Houston, TX 77030, USA; Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX 77030, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ccell.2017.04.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5502825PMC
June 2017

Cellular interactions of the phosphorylated form of AKT in prostate cancer.

Hum Pathol 2017 05 11;63:98-109. Epub 2017 Mar 11.

Department of Pathology, Baylor College of Medicine, Houston, TX 77030; The Scott Department of Urology, Baylor College of Medicine, Houston, TX 77030; Department of Pathology and Laboratory Medicine, University of Texas Health Science Center, Houston, TX 77030. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.humpath.2017.02.014DOI Listing
May 2017

A Versatile Tumor Gene Deletion System Reveals a Crucial Role for FGFR1 in Breast Cancer Metastasis.

Neoplasia 2017 May 20;19(5):421-428. Epub 2017 Apr 20.

Department of Molecular and Cellular Biology, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, United States. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.neo.2017.03.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5402631PMC
May 2017

Combination treatment of prostate cancer with FGF receptor and AKT kinase inhibitors.

Oncotarget 2017 Jan;8(4):6179-6192

Department of Pathology and Immunology, Baylor College of Medicine and Michael E. DeBakey Department of Veterans Affairs Medical Center Baylor College of Medicine, Houston, 77030, TX, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.18632/oncotarget.14049DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5351622PMC
January 2017

MNX1 Is Oncogenically Upregulated in African-American Prostate Cancer.

Cancer Res 2016 11 30;76(21):6290-6298. Epub 2016 Aug 30.

Department of Pathology and Immunology and Michael E. DeBakey Veterans Affairs Medical Center, Houston, Texas.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/0008-5472.CAN-16-0087DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5093064PMC
November 2016

The Germ Cell Gene TDRD1 as an ERG Target Gene and a Novel Prostate Cancer Biomarker.

Prostate 2016 10 8;76(14):1271-84. Epub 2016 Jun 8.

Departments of Medicine-Hematology and Oncology, Baylor College of Medicine, Houston, Texas.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/pros.23213DOI Listing
October 2016

Neuronal Trans-Differentiation in Prostate Cancer Cells.

Prostate 2016 10 12;76(14):1312-25. Epub 2016 Jul 12.

Department of Pathology and Laboratory Medicine, University of Texas Health Science Center at Houston, Houston, Texas.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/pros.23221DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5815867PMC
October 2016

Non-Cell-Autonomous Regulation of Prostate Epithelial Homeostasis by Androgen Receptor.

Mol Cell 2016 09 1;63(6):976-89. Epub 2016 Sep 1.

Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX 77030, USA; Dan L. Duncan Cancer Center, Baylor College of Medicine, Houston, TX 77030, USA; Department of Pathology and Immunology, Baylor College of Medicine, Houston, TX 77030, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.molcel.2016.07.025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5026614PMC
September 2016

Nuclear Receptor Corepressor 1 Expression and Output Declines with Prostate Cancer Progression.

Clin Cancer Res 2016 08 11;22(15):3937-49. Epub 2016 Mar 11.

Department of Cellular Biology and Pharmacology, Herbert Wertheim College of Medicine, Florida International University, Miami, Florida. Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, Texas. Biomolecular Sciences Institute, School of Integrated Science and Humanity, Florida international University, Miami, Florida.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/1078-0432.CCR-15-1983DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4970919PMC
August 2016

GRK3 is a direct target of CREB activation and regulates neuroendocrine differentiation of prostate cancer cells.

Oncotarget 2016 Jul;7(29):45171-45185

Texas Therapeutics Institute, Brown Foundation Institute of Molecular Medicine, University of Texas Health Science Center at Houston, Houston, TX, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.18632/oncotarget.9359DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5216714PMC
July 2016

The essential role of GATA transcription factors in adult murine prostate.

Oncotarget 2016 Jul;7(30):47891-47903

Department of Medicine, Section of Hematology and Oncology, Baylor College of Medicine, Houston, TX, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.18632/oncotarget.10294DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5216986PMC
July 2016

A Versatile Gene Delivery System for Efficient and Tumor Specific Gene Manipulation .

Discoveries (Craiova) 2016 Apr-Jun;4(2). Epub 2016 Jun 22.

Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX, 77030, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.15190/d.2016.5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4926771PMC
June 2016

The tumor suppressive miR-200b subfamily is an ERG target gene in human prostate tumors.

Oncotarget 2016 Jun;7(25):37993-38003

Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, Texas, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.18632/oncotarget.9366DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5122366PMC
June 2016

The role of ATP-binding cassette transporter genes in the progression of prostate cancer.

Prostate 2016 Apr 28;76(5):434-44. Epub 2015 Dec 28.

Department of Medical Genetics, Cerrahpasa Medical School, Istanbul University, Istanbul, Turkey.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/pros.23137DOI Listing
April 2016

Cells Comprising the Prostate Cancer Microenvironment Lack Recurrent Clonal Somatic Genomic Aberrations.

Mol Cancer Res 2016 Apr 11;14(4):374-84. Epub 2016 Jan 11.

Division of Human Biology, Fred Hutchinson Cancer Research Center, Seattle, Washington. Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington. Division of Clinical Research, Fred Hutchinson Cancer Research Center, Seattle, Washington. Department of Pathology, University of Washington, Seattle, Washington. Department of Urology, University of Washington, Seattle, Washington. Department of Medicine, University of Washington, Seattle, Washington.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/1541-7786.MCR-15-0330DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5582956PMC
April 2016

Dysregulation of miRNAs-COUP-TFII-FOXM1-CENPF axis contributes to the metastasis of prostate cancer.

Nat Commun 2016 04 25;7:11418. Epub 2016 Apr 25.

Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, Texas 77030, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ncomms11418DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4848536PMC
April 2016

Aberrant Activation of the RANK Signaling Receptor Induces Murine Salivary Gland Tumors.

PLoS One 2015 10;10(6):e0128467. Epub 2015 Jun 10.

Department of Molecular Cellular Biology, Baylor College of Medicine, One Baylor Plaza, Houston, Texas, United States of America.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0128467PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4464738PMC
March 2016

The role of miR-145 in stem cell characteristics of human laryngeal squamous cell carcinoma Hep-2 cells.

Tumour Biol 2016 Mar 22;37(3):4183-92. Epub 2015 Oct 22.

Department of Medical Genetics, Cerrahpasa Medical School, Istanbul University, Istanbul, Turkey.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s13277-015-4219-zDOI Listing
March 2016

A Polymorphism in the FGFR4 Gene Is Associated With Risk of Neuroblastoma and Altered Receptor Degradation.

J Pediatr Hematol Oncol 2016 Mar;38(2):131-8

*Section of Hematology-Oncology, Department of Pediatrics, Texas Children's Cancer Center, Baylor College of Medicine †Department of Neurobiology and Anatomy, University of Texas Medical School ‡Department of Pathology & Immunology, Baylor College of Medicine and Michael E. DeBakey VAMC, Houston, TX.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/MPH.0000000000000506DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4758892PMC
March 2016

Role of miR-145 in human laryngeal squamous cell carcinoma.

Head Neck 2016 Feb 16;38(2):260-6. Epub 2015 Jun 16.

Department of Medical Genetics, Cerrahpasa Medical School, Istanbul University, Istanbul, Turkey.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/hed.23890DOI Listing
February 2016

Oxidative stress promotes benign prostatic hyperplasia.

Prostate 2016 Jan 29;76(1):58-67. Epub 2015 Sep 29.

Department of Pathology and Immunology, Baylor College of Medicine and Michael E. DeBakey Department of Veterans Affairs Medical Center, Houston, Texas.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/pros.23100DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5469601PMC
January 2016

Comprehensive Molecular Characterization of Papillary Renal-Cell Carcinoma.

Authors:
W Marston Linehan Paul T Spellman Christopher J Ricketts Chad J Creighton Suzanne S Fei Caleb Davis David A Wheeler Bradley A Murray Laura Schmidt Cathy D Vocke Myron Peto Abu Amar M Al Mamun Eve Shinbrot Anurag Sethi Samira Brooks W Kimryn Rathmell Angela N Brooks Katherine A Hoadley A Gordon Robertson Denise Brooks Reanne Bowlby Sara Sadeghi Hui Shen Daniel J Weisenberger Moiz Bootwalla Stephen B Baylin Peter W Laird Andrew D Cherniack Gordon Saksena Scott Haake Jun Li Han Liang Yiling Lu Gordon B Mills Rehan Akbani Mark D M Leiserson Benjamin J Raphael Pavana Anur Donald Bottaro Laurence Albiges Nandita Barnabas Toni K Choueiri Bogdan Czerniak Andrew K Godwin A Ari Hakimi Thai H Ho James Hsieh Michael Ittmann William Y Kim Bhavani Krishnan Maria J Merino Kenna R Mills Shaw Victor E Reuter Ed Reznik Carl S Shelley Brian Shuch Sabina Signoretti Ramaprasad Srinivasan Pheroze Tamboli George Thomas Satish Tickoo Kenneth Burnett Daniel Crain Johanna Gardner Kevin Lau David Mallery Scott Morris Joseph D Paulauskis Robert J Penny Candace Shelton W Troy Shelton Mark Sherman Eric Thompson Peggy Yena Melissa T Avedon Jay Bowen Julie M Gastier-Foster Mark Gerken Kristen M Leraas Tara M Lichtenberg Nilsa C Ramirez Tracie Santos Lisa Wise Erik Zmuda John A Demchok Ina Felau Carolyn M Hutter Margi Sheth Heidi J Sofia Roy Tarnuzzer Zhining Wang Liming Yang Jean C Zenklusen Jiashan Zhang Brenda Ayala Julien Baboud Sudha Chudamani Jia Liu Laxmi Lolla Rashi Naresh Todd Pihl Qiang Sun Yunhu Wan Ye Wu Adrian Ally Miruna Balasundaram Saianand Balu Rameen Beroukhim Tom Bodenheimer Christian Buhay Yaron S N Butterfield Rebecca Carlsen Scott L Carter Hsu Chao Eric Chuah Amanda Clarke Kyle R Covington Mahmoud Dahdouli Ninad Dewal Noreen Dhalla Harsha V Doddapaneni Jennifer A Drummond Stacey B Gabriel Richard A Gibbs Ranabir Guin Walker Hale Alicia Hawes D Neil Hayes Robert A Holt Alan P Hoyle Stuart R Jefferys Steven J M Jones Corbin D Jones Divya Kalra Christie Kovar Lora Lewis Jie Li Yussanne Ma Marco A Marra Michael Mayo Shaowu Meng Matthew Meyerson Piotr A Mieczkowski Richard A Moore Donna Morton Lisle E Mose Andrew J Mungall Donna Muzny Joel S Parker Charles M Perou Jeffrey Roach Jacqueline E Schein Steven E Schumacher Yan Shi Janae V Simons Payal Sipahimalani Tara Skelly Matthew G Soloway Carrie Sougnez Angela Tam Donghui Tan Nina Thiessen Umadevi Veluvolu Min Wang Matthew D Wilkerson Tina Wong Junyuan Wu Liu Xi Jane Zhou Jason Bedford Fengju Chen Yao Fu Mark Gerstein David Haussler Katayoon Kasaian Phillip Lai Shiyun Ling Amie Radenbaugh David Van Den Berg John N Weinstein Jingchun Zhu Monique Albert Iakovina Alexopoulou Jeremiah J Andersen J Todd Auman John Bartlett Sheldon Bastacky Julie Bergsten Michael L Blute Lori Boice Roni J Bollag Jeff Boyd Erik Castle Ying-Bei Chen John C Cheville Erin Curley Benjamin Davies April DeVolk Rajiv Dhir Laura Dike John Eckman Jay Engel Jodi Harr Ronald Hrebinko Mei Huang Lori Huelsenbeck-Dill Mary Iacocca Bruce Jacobs Michael Lobis Jodi K Maranchie Scott McMeekin Jerome Myers Joel Nelson Jeremy Parfitt Anil Parwani Nicholas Petrelli Brenda Rabeno Somak Roy Andrew L Salner Joel Slaton Melissa Stanton R Houston Thompson Leigh Thorne Kelinda Tucker Paul M Weinberger Cynthia Winemiller Leigh Anne Zach Rosemary Zuna

miR-1 and miR-133b are differentially expressed in patients with recurrent prostate cancer.

PLoS One 2014 26;9(6):e98675. Epub 2014 Jun 26.

Department of Medical Genetics, Istanbul University, Cerrahpasa Medical School, Istanbul, Turkey; Biruni University, Istanbul, Turkey; Department of Pathology & Immunology, Baylor College of Medicine, and Michael E. DeBakey VAMC, Houston, Texas, United States of America.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0098675PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4072786PMC
October 2015

Overexpression of miR-145-5p inhibits proliferation of prostate cancer cells and reduces SOX2 expression.

Cancer Invest 2015 Jul 7;33(6):251-8. Epub 2015 May 7.

1Department of Medical Genetics, Cerrahpasa Medical School, Istanbul University, Istanbul, Turkey.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3109/07357907.2015.1025407DOI Listing
July 2015

FGF23 promotes prostate cancer progression.

Oncotarget 2015 Jul;6(19):17291-301

Department of Pathology and Immunology, Baylor College of Medicine and Michael E. DeBakey Dept. of Veterans Affairs Medical Center, Houston, Texas, USA.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4627308PMC
http://dx.doi.org/10.18632/oncotarget.4174DOI Listing
July 2015

Expression of ERG protein in prostate cancer: variability and biological correlates.

Endocr Relat Cancer 2015 Jun;22(3):277-87

Department of Pathology and Laboratory MedicineUniversity of Texas Health Sciences Center Medical School, Houston, Texas, USADan L. Duncan Cancer CenterHouston, Texas, USADepartment of Pathology and ImmunologyBaylor College of Medicine, One Baylor Plaza, Houston, Texas 77030, USADepartment of Veterans AffairsMichael E. DeBakey VA Medical Center, Houston, Texas 77030, USA Department of Pathology and Laboratory MedicineUniversity of Texas Health Sciences Center Medical School, Houston, Texas, USADan L. Duncan Cancer CenterHouston, Texas, USADepartment of Pathology and ImmunologyBaylor College of Medicine, One Baylor Plaza, Houston, Texas 77030, USADepartment of Veterans AffairsMichael E. DeBakey VA Medical Center, Houston, Texas 77030, USA

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1530/ERC-14-0586DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4432248PMC
June 2015

Heparanase promotes tumor infiltration and antitumor activity of CAR-redirected T lymphocytes.

Nat Med 2015 May 13;21(5):524-9. Epub 2015 Apr 13.

1] Center for Cell and Gene Therapy, Baylor College of Medicine and Houston Methodist Hospital, Houston, Texas, USA. [2] Department of Pathology and Immunology, Baylor College of Medicine, Houston, Texas, USA. [3] Department of Medicine, Baylor College of Medicine, Houston, Texas, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nm.3833DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4425589PMC
May 2015

Function of phosphorylation of NF-kB p65 ser536 in prostate cancer oncogenesis.

Oncotarget 2015 Mar;6(8):6281-94

Department of Pathology and Immunology, Baylor College of Medicine and Michael E. DeBakey Deptartment of Veterans Affairs Medical Center, Houston, Texas, USA.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4467437PMC
http://dx.doi.org/10.18632/oncotarget.3366DOI Listing
March 2015

Identification of microRNAs differentially expressed in prostatic secretions of patients with prostate cancer.

Int J Cancer 2015 Feb 7;136(4):875-9. Epub 2014 Jul 7.

Department of Medical Genetics, Istanbul University, Cerrahpasa Medical School, Istanbul, Turkey; Department of Molecular Biology and Genetics, Biruni University, Istanbul, Turkey.

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1002/ijc.29054
Publisher Site
http://dx.doi.org/10.1002/ijc.29054DOI Listing
February 2015

Differential expression of stem cell markers and ABCG2 in recurrent prostate cancer.

Prostate 2014 Nov 29;74(15):1498-505. Epub 2014 Aug 29.

Department of Medical Genetics, Istanbul University, Cerrahpasa Medical School, Istanbul, Turkey; Biruni University, Istanbul, Turkey.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/pros.22867DOI Listing
November 2014

Stromal TGF-β signaling induces AR activation in prostate cancer.

Oncotarget 2014 Nov;5(21):10854-69

Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX 77030.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4279415PMC
http://dx.doi.org/10.18632/oncotarget.2536DOI Listing
November 2014

The prostate cancer TMPRSS2:ERG fusion synergizes with the vitamin D receptor (VDR) to induce CYP24A1 expression-limiting VDR signaling.

Endocrinology 2014 Sep 13;155(9):3262-73. Epub 2014 Jun 13.

Departments of Molecular and Cellular Biology (J.-S.K., J.M.R., W.E.B., N.L.W.) and Pathology and Immunology (L.S., J.W., M.M.I.), Baylor College of Medicine, Houston, Texas 77030.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1210/en.2013-2019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5377584PMC
September 2014

Increased Notch signalling inhibits anoikis and stimulates proliferation of prostate luminal epithelial cells.

Nat Commun 2014 Jul 22;5:4416. Epub 2014 Jul 22.

1] Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, Texas 77030, USA [2] Department of Pathology and Immunology, Baylor College of Medicine, Houston, Texas 77030, USA [3] Dan L. Duncan Cancer Center, Baylor College of Medicine, Houston, Texas 77030, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ncomms5416DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4167399PMC
July 2014

HLA-restricted NY-ESO-1 peptide immunotherapy for metastatic castration resistant prostate cancer.

Invest New Drugs 2014 Apr 23;32(2):235-242. Epub 2013 Apr 23.

Department of Medicine, Section of Medical Oncology, Baylor College of Medicine, Houston, TX, USA; Michael E. DeBakey Veterans Affairs Medical Center, VA 111H, 2002 Holcombe Blvd, Houston, TX 77030, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s10637-013-9960-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4100683PMC
April 2014

The senescence-associated secretory phenotype promotes benign prostatic hyperplasia.

Am J Pathol 2014 Mar 13;184(3):721-31. Epub 2014 Jan 13.

Department of Pathology and Immunology, Baylor College of Medicine, and the Michael E. DeBakey Department of Veterans Affairs Medical Center, Houston, Texas. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ajpath.2013.11.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3936307PMC
March 2014

T lymphocytes redirected against the chondroitin sulfate proteoglycan-4 control the growth of multiple solid tumors both in vitro and in vivo.

Clin Cancer Res 2014 Feb 13;20(4):962-71. Epub 2013 Dec 13.

Authors' Affiliations: Center for Cell and Gene Therapy; Departments of Pediatrics, Pathology and Immunology, and Medicine, Interdepartmental Program in Translational Biology and Molecular Medicine, Baylor College of Medicine; Houston Methodist Hospital and Texas Children's Hospital; Department of Surgery, Michael E. DeBakey Department of Veterans Affairs Medical Center; Dan L. Duncan Cancer Center Division of Biostatistics, Baylor College of Medicine, Houston, Texas; and Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/1078-0432.CCR-13-2218DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3944408PMC
February 2014

Prostatic inflammation enhances basal-to-luminal differentiation and accelerates initiation of prostate cancer with a basal cell origin.

Proc Natl Acad Sci U S A 2014 Feb 23;111(5):E592-600. Epub 2013 Dec 23.

Departments of Molecular and Cellular Biology and Pathology and Immunology and the Dan L. Duncan Cancer Center, Baylor College of Medicine, Houston, TX 77030.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1073/pnas.1318157111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3918789PMC
February 2014

Genes upregulated in prostate cancer reactive stroma promote prostate cancer progression in vivo.

Clin Cancer Res 2014 Jan 22;20(1):100-9. Epub 2013 Oct 22.

Authors' Affiliations: Departments of Pathology and Immunology and Molecular and Cellular Biology, Baylor College of Medicine; and Michael E. DeBakey Department of Veterans Affairs Medical Center, Houston, Texas.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/1078-0432.CCR-13-1184DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3947312PMC
January 2014

FGFR1-WNT-TGF-β signaling in prostate cancer mouse models recapitulates human reactive stroma.

Cancer Res 2014 Jan 4;74(2):609-20. Epub 2013 Dec 4.

Authors' Affiliations: Departments of Pathology and Immunology and Molecular and Cellular Biology; and Dan L Duncan Cancer Center, Baylor College of Medicine, Houston; M.E. DeBakey, Department of Veterans Affairs Medical Center, Houston, Texas.

View Article

Download full-text PDF

Source
http://cancerres.aacrjournals.org/lookup/doi/10.1158/0008-54
Publisher Site
http://dx.doi.org/10.1158/0008-5472.CAN-13-1093DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3905049PMC
January 2014

MicroRNA expression profiling reveals the potential function of microRNA-31 in chordomas.

J Neurooncol 2013 Nov 3;115(2):143-51. Epub 2013 Aug 3.

Department of Medical Genetics, Yeditepe University Medical School and Yeditepe University Hospital, Istanbul, Turkey.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s11060-013-1211-6DOI Listing
November 2013

Semaphorin 4F as a critical regulator of neuroepithelial interactions and a biomarker of aggressive prostate cancer.

Clin Cancer Res 2013 Nov 4;19(22):6101-11. Epub 2013 Oct 4.

Authors' Affiliations: Department of Pathology and Laboratory Medicine, University of Texas Health Sciences Center Medical School; Departments of Pathology & Immunology and Molecular & Cell Biology, Dan L. Duncan Cancer Center, Scott Department of Urology, Baylor College of Medicine; Department of Urology, The Methodist Hospital, Houston, Texas; and Department of Internal Medicine, Detroit Medical Center, Sinai-Grace Hospital, Wayne State University, Detroit, Michigan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/1078-0432.CCR-12-3669DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3898797PMC
November 2013

ERK and AKT signaling drive MED1 overexpression in prostate cancer in association with elevated proliferation and tumorigenicity.

Mol Cancer Res 2013 Jul 28;11(7):736-47. Epub 2013 Mar 28.

Department of Physiology and Biophysics, Robert Wood Johnson Medical School, UMDNJ, 683 Hoes Lane, Piscataway, New Jersey 08854, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/1541-7786.MCR-12-0618DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5838364PMC
July 2013

FGFR1 is essential for prostate cancer progression and metastasis.

Cancer Res 2013 Jun 10;73(12):3716-24. Epub 2013 Apr 10.

Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX 77030, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/0008-5472.CAN-12-3274DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3686853PMC
June 2013

SULT2B1b sulfotransferase: induction by vitamin D receptor and reduced expression in prostate cancer.

Mol Endocrinol 2013 Jun 11;27(6):925-39. Epub 2013 Apr 11.

Department of Molecular Medicine, University of Texas Health Science Center at San Antonio, San Antonio, Texas 78245, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1210/me.2012-1369DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3656233PMC
June 2013

Endocrine fibroblast growth factor FGF19 promotes prostate cancer progression.

Cancer Res 2013 Apr 25;73(8):2551-62. Epub 2013 Feb 25.

Department of Pathology and Immunology and Michael E. DeBakey Department of Veterans Affairs Medical Center, Baylor College of Medicine, Houston, TX 77030, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/0008-5472.CAN-12-4108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3630260PMC
April 2013

IRIS iQ200 workstation as a screen for performing urine culture.

Diagn Microbiol Infect Dis 2013 Jan 24;75(1):5-8. Epub 2012 Oct 24.

Medical Care Line (Infectious Disease Section), Michael E. DeBakey Veterans Affairs Medical Center, Houston, TX 77030, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.diagmicrobio.2012.08.026DOI Listing
January 2013

COUP-TFII inhibits TGF-β-induced growth barrier to promote prostate tumorigenesis.

Nature 2013 Jan 28;493(7431):236-40. Epub 2012 Nov 28.

Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, Texas 77030, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nature11674DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4022346PMC
January 2013

Highly specific targeting of the TMPRSS2/ERG fusion gene using liposomal nanovectors.

Clin Cancer Res 2012 Dec 10;18(24):6648-57. Epub 2012 Oct 10.

Department of Pathology and Immunology and Michael E. DeBakey Department of Veterans Affairs Medical Center, Baylor College of Medicine, Houston, Texas 77030, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/1078-0432.CCR-12-2715DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3525716PMC
December 2012

Frequent heterogeneous missense mutations of GGAP2 in prostate cancer: implications for tumor biology, clonality and mutation analysis.

PLoS One 2012 28;7(2):e32708. Epub 2012 Feb 28.

Department of Pathology and Immunology, Baylor College of Medicine, Houston, Texas, United States of America.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0032708PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3289671PMC
July 2012

Targeting fibroblast growth factor receptor signaling inhibits prostate cancer progression.

Clin Cancer Res 2012 Jul 9;18(14):3880-8. Epub 2012 May 9.

Department of Pathology and Immunology, Baylor College of Medicine, Houston, TX 77030, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/1078-0432.CCR-11-3214DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4654778PMC
July 2012

Common structural and epigenetic changes in the genome of castration-resistant prostate cancer.

Cancer Res 2012 Feb 7;72(3):616-25. Epub 2011 Dec 7.

Division on Genitourinary Medical Oncology, Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, California 94143, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/0008-5472.CAN-11-2079DOI Listing
February 2012

Adult murine prostate basal and luminal cells are self-sustained lineages that can both serve as targets for prostate cancer initiation.

Cancer Cell 2012 Feb;21(2):253-65

Department of Molecular and Cellular Biology, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ccr.2012.01.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3285423PMC
February 2012