Michael Inouye

Michael Inouye

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Michael Inouye

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Towards clinical utility of polygenic risk scores.

Hum Mol Genet 2019 Jul 31. Epub 2019 Jul 31.

Cambridge Baker Systems Genomics Initiative, Department of Public Health and Primary Care, University of Cambridge, Cambridge CB1 8RN, United Kingdom.

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http://dx.doi.org/10.1093/hmg/ddz187DOI Listing
July 2019

Gene Regulatory Networks to Explain Coronary Artery Disease Heritability.

J Am Coll Cardiol 2019 Jun;73(23):2958-2960

Cambridge Baker Systems Genomics Initiative, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom.

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http://dx.doi.org/10.1016/j.jacc.2019.03.511DOI Listing
June 2019

FastSpar: rapid and scalable correlation estimation for compositional data.

Bioinformatics 2019 Mar;35(6):1064-1066

Department of Biochemistry and Molecular Biology, Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Parkville, Australia.

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http://dx.doi.org/10.1093/bioinformatics/bty734DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6419895PMC
March 2019

Power, false discovery rate and Winner's Curse in eQTL studies.

Nucleic Acids Res 2018 12;46(22):e133

Cambridge Baker Systems Genomics Initiative, Baker Heart and Diabetes Institute, 75 Commercial Rd, Melbourne 3004, Victoria, Australia.

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http://dx.doi.org/10.1093/nar/gky780DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6294523PMC
December 2018

Airway Microbiota Dynamics Uncover a Critical Window for Interplay of Pathogenic Bacteria and Allergy in Childhood Respiratory Disease.

Cell Host Microbe 2018 09;24(3):341-352.e5

Cambridge Baker Systems Genomics Initiative, Baker Heart and Diabetes Institute, Melbourne, VIC 3004, Australia; Cambridge Baker Systems Genomics Initiative, Department of Public Health and Primary Care, University of Cambridge, Cambridge CB1 8RN, UK; School of BioSciences, The University of Melbourne, Parkville, VIC 3010, Australia; Telethon Kids Institute, The University of Western Australia, West Perth, WA, Australia; Department of Clinical Pathology, The University of Melbourne, Parkville, VIC 3010, Australia; The Alan Turing Institute, London, UK. Electronic address:

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http://dx.doi.org/10.1016/j.chom.2018.08.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6291254PMC
September 2018

Identification of expression quantitative trait loci associated with schizophrenia and affective disorders in normal brain tissue.

PLoS Genet 2018 08 24;14(8):e1007607. Epub 2018 Aug 24.

Department of Clinical Pathology, The University of Melbourne, Parkville, Victoria, Australia.

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http://dx.doi.org/10.1371/journal.pgen.1007607DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6126875PMC
August 2018

FlashPCA2: principal component analysis of Biobank-scale genotype datasets.

Bioinformatics 2017 Sep;33(17):2776-2778

Centre for Systems Genomics, School of BioSciences.

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http://dx.doi.org/10.1093/bioinformatics/btx299DOI Listing
September 2017

An exposome perspective: Early-life events and immune development in a changing world.

J Allergy Clin Immunol 2017 Jul;140(1):24-40

Children's Health and Environment Program, Child Health Research Centre, University of Queensland, Brisbane, Australia.

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http://dx.doi.org/10.1016/j.jaci.2017.05.015DOI Listing
July 2017

Corrigendum: serotyping of from short read data identifies limited novel O-loci but extensive diversity of O:H serotype combinations within and between pathogenic lineages.

Microb Genom 2017 07 1;3(7):e000109. Epub 2017 Aug 1.

3​Department of Biochemistry and Molecular Biology, Bio21 Molecular Science and Biotechnology Institute, University of Melbourne, Parkville, Victoria 3010, Australia.

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http://dx.doi.org/10.1099/mgen.0.000109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5605953PMC
July 2017

Genetic loci associated with coronary artery disease harbor evidence of selection and antagonistic pleiotropy.

PLoS Genet 2017 Jun 22;13(6):e1006328. Epub 2017 Jun 22.

Centre for Systems Genomics, School of BioSciences, The University of Melbourne, Parkville, Victoria, Australia.

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http://dx.doi.org/10.1371/journal.pgen.1006328DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5480811PMC
June 2017

Microbial Factors Associated with Postoperative Crohn's Disease Recurrence.

J Crohns Colitis 2017 Feb 27;11(2):191-203. Epub 2016 Jul 27.

Enteric Virus Group, Murdoch Children's Research Institute, Parkville, VIC, Australia.

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http://dx.doi.org/10.1093/ecco-jcc/jjw136DOI Listing
February 2017

Vitamin D over the first decade and susceptibility to childhood allergy and asthma.

J Allergy Clin Immunol 2017 02 7;139(2):472-481.e9. Epub 2016 Oct 7.

Telethon Kids Institute, University of Western Australia, Perth, Australia; University of Queensland, Brisbane, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2016.07.032DOI Listing
February 2017

Genomic prediction of coronary heart disease.

Eur Heart J 2016 Nov 21;37(43):3267-3278. Epub 2016 Sep 21.

Centre for Systems Genomics, School of BioSciences, The University of Melbourne, Parkville, Victoria 3010, Australia

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http://dx.doi.org/10.1093/eurheartj/ehw450DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5146693PMC
November 2016

Metabolomics in epidemiology: from metabolite concentrations to integrative reaction networks.

Int J Epidemiol 2016 10 26;45(5):1319-1328. Epub 2016 Apr 26.

Centre for Systems Genomics

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http://dx.doi.org/10.1093/ije/dyw046DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5100607PMC
October 2016

A Scalable Permutation Approach Reveals Replication and Preservation Patterns of Network Modules in Large Datasets.

Cell Syst 2016 07;3(1):71-82

Centre for Systems Genomics, The University of Melbourne, Parkville, VIC 3010, Australia; Department of Pathology, The University of Melbourne, Parkville, VIC 3010, Australia; School of BioSciences, The University of Melbourne, Parkville, VIC 3010, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.cels.2016.06.012DOI Listing
July 2016

The Biomarker GlycA Is Associated with Chronic Inflammation and Predicts Long-Term Risk of Severe Infection.

Cell Syst 2015 Oct 22;1(4):293-301. Epub 2015 Oct 22.

Centre for Systems Genomics, School of BioSciences, The University of Melbourne, Parkville, 3010 Victoria, Australia; Department of Pathology, The University of Melbourne, Parkville, 3010 Victoria, Australia; Department of Microbiology and Immunology, The University of Melbourne, Parkville, 3010 Victoria, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.cels.2015.09.007DOI Listing
October 2015

Post-infectious group A streptococcal autoimmune syndromes and the heart.

Autoimmun Rev 2015 Aug 17;14(8):710-25. Epub 2015 Apr 17.

Inflammation Division, Water and Eliza Hall Institute of Medical Research, Parkville, VIC 3052, Australia; Department of Medical Biology, University of Melbourne, Parkville, VIC 3052, Australia; Rheumatology Unit, Royal Melbourne Hospital, Parkville, VIC 3052, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.autrev.2015.04.005DOI Listing
August 2015

Genomic risk prediction of complex human disease and its clinical application.

Curr Opin Genet Dev 2015 Aug 24;33:10-6. Epub 2015 Jul 24.

Medical Systems Biology, Department of Pathology and Department of Microbiology & Immunology, The University of Melbourne, Parkville 3010, Victoria, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.gde.2015.06.005DOI Listing
August 2015

Genomic prediction of celiac disease targeting HLA-positive individuals.

Genome Med 2015 16;7(1):72. Epub 2015 Jul 16.

Centre for Systems Genomics, School of BioSciences, The University of Melbourne, Parkville, 3010 Victoria Australia ; Medical Systems Biology, Department of Pathology and Department of Microbiology & Immunology, The University of Melbourne, Parkville, 3010 Victoria Australia.

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http://dx.doi.org/10.1186/s13073-015-0196-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4523954PMC
August 2015

Recent advances in characterizing the gastrointestinal microbiome in Crohn's disease: a systematic review.

Inflamm Bowel Dis 2015 Jun;21(6):1219-28

*Department of Gastroenterology, St Vincent's Hospital Melbourne, Australia; †Department of Pathology, University of Melbourne, Australia; ‡Imperial College, London, United Kingdom; and §Enteric Virus Group, Murdoch Children's Research Institute, Melbourne, Australia.

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http://dx.doi.org/10.1097/MIB.0000000000000382DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4450900PMC
June 2015

Transcriptional profiling of mouse B cell terminal differentiation defines a signature for antibody-secreting plasma cells.

Nat Immunol 2015 Jun 20;16(6):663-73. Epub 2015 Apr 20.

1] The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia. [2] Department of Medical Biology, The University of Melbourne, Parkville, Victoria, Australia.

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http://dx.doi.org/10.1038/ni.3154DOI Listing
June 2015

The infant nasopharyngeal microbiome impacts severity of lower respiratory infection and risk of asthma development.

Cell Host Microbe 2015 May 9;17(5):704-15. Epub 2015 Apr 9.

Medical Systems Biology, Department of Pathology and Department of Microbiology & Immunology, The University of Melbourne, Parkville, VIC 3010, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.chom.2015.03.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4433433PMC
May 2015

Recovery from severe H7N9 disease is associated with diverse response mechanisms dominated by CD8⁺ T cells.

Nat Commun 2015 May 13;6:6833. Epub 2015 May 13.

Shanghai Public Health Clinical Center and Institutes of Biomedical Sciences, Key Laboratory of Medical Molecular Virology of Ministry of Education/Health, Shanghai Medical College, Fudan University, Shanghai 201508, China.

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http://dx.doi.org/10.1038/ncomms7833DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4479016PMC
May 2015

High performance computing enabling exhaustive analysis of higher order single nucleotide polymorphism interaction in Genome Wide Association Studies.

Health Inf Sci Syst 2015 24;3(Suppl 1 HISA Big Data in Biomedicine and Healthcare 2013 Con):S3. Epub 2015 Feb 24.

IBM Research - Australia, 204 Lygon Street, Carlton, VIC, 3053, Australia ; Department of Computing and Information Systems, University of Melbourne, Parkville, VIC, 3010, Australia.

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http://dx.doi.org/10.1186/2047-2501-3-S1-S3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4383059PMC
April 2015

Fast principal component analysis of large-scale genome-wide data.

PLoS One 2014 9;9(4):e93766. Epub 2014 Apr 9.

Medical Systems Biology, Department of Pathology and Department of Microbiology & Immunology, University of Melbourne, Parkville, Victoria, Australia.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0093766PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3981753PMC
January 2015

Towards a molecular systems model of coronary artery disease.

Curr Cardiol Rep 2014 ;16(6):488

Medical Systems Biology, Department of Pathology and Department of Microbiology & Immunology, The University of Melbourne, Parkville, Victoria, 3010, Australia.

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http://dx.doi.org/10.1007/s11886-014-0488-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4050311PMC
January 2015

SRST2: Rapid genomic surveillance for public health and hospital microbiology labs.

Genome Med 2014 20;6(11):90. Epub 2014 Nov 20.

Department of Biochemistry and Molecular Biology, Bio21 Molecular Science and Biotechnology Institute, University of Melbourne, Parkville, Victoria 3010 Australia.

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http://dx.doi.org/10.1186/s13073-014-0090-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4237778PMC
November 2014

The transcription factors IRF8 and PU.1 negatively regulate plasma cell differentiation.

J Exp Med 2014 Oct 6;211(11):2169-81. Epub 2014 Oct 6.

The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria 3050, Australia Department of Medical Biology, Department of Pathology, Department of Microbiology and Immunology, and Department of Computing and Information Systems, University of Melbourne, Parkville, Victoria 3010, Australia

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http://dx.doi.org/10.1084/jem.20140425DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4203955PMC
October 2014

Elucidation of pathways driving asthma pathogenesis: development of a systems-level analytic strategy.

Front Immunol 2014 23;5:447. Epub 2014 Sep 23.

Medical Systems Biology, Department of Pathology, The University of Melbourne , Parkville, VIC , Australia ; Telethon Kids Institute, The University of Western Australia , West Perth, WA , Australia ; Medical Systems Biology, Department of Microbiology and Immunology, The University of Melbourne , Parkville, VIC , Australia.

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http://dx.doi.org/10.3389/fimmu.2014.00447DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4172064PMC
October 2014

Distribution and medical impact of loss-of-function variants in the Finnish founder population.

PLoS Genet 2014 Jul 31;10(7):e1004494. Epub 2014 Jul 31.

Analytic and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts, United States of America; Program in Medical and Population Genetics, Broad Institute, Cambridge, Massachusetts, United States of America; Institute for Molecular Medicine Finland, University of Helsinki, Helsinki, Finland; Psychiatric & Neurodevelopmental Genetics Unit, Department of Psychiatry, Massachusetts General Hospital, Boston, Massachusetts, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.1004494DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4117444PMC
July 2014

Look, no hands! Spectral biomarkers from genetic association studies.

Genome Med 2013 15;5(2):14. Epub 2013 Feb 15.

Medical Systems Biology, Department of Pathology and Department of Microbiology & Immunology, The University of Melbourne, Parkville, Victoria 3010, Australia.

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http://dx.doi.org/10.1186/gm418DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3706812PMC
May 2014

Accurate and robust genomic prediction of celiac disease using statistical learning.

PLoS Genet 2014 Feb 13;10(2):e1004137. Epub 2014 Feb 13.

Medical Systems Biology, Department of Pathology and Department of Microbiology & Immunology, The University of Melbourne, Parkville, Victoria, Australia.

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http://dx.doi.org/10.1371/journal.pgen.1004137DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3923679PMC
February 2014

The developmental pathway for CD103(+)CD8+ tissue-resident memory T cells of skin.

Nat Immunol 2013 Dec 27;14(12):1294-301. Epub 2013 Oct 27.

1] Department of Microbiology and Immunology, The University of Melbourne, Parkville, Australia. [2].

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http://dx.doi.org/10.1038/ni.2744DOI Listing
December 2013

GWIS--model-free, fast and exhaustive search for epistatic interactions in case-control GWAS.

BMC Genomics 2013 28;14 Suppl 3:S10. Epub 2013 May 28.

National ICT Australia Victorian Research Lab, The University of Melbourne, Parkville, Victoria, Australia.

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http://dx.doi.org/10.1186/1471-2164-14-S3-S10DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3665501PMC
October 2013

Performance and robustness of penalized and unpenalized methods for genetic prediction of complex human disease.

Genet Epidemiol 2013 Feb 30;37(2):184-95. Epub 2012 Nov 30.

Medical Systems Biology, Departments of Pathology and of Microbiology & Immunology, The University of Melbourne, Parkville, VIC, Australia.

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http://doi.wiley.com/10.1002/gepi.21698
Publisher Site
http://dx.doi.org/10.1002/gepi.21698DOI Listing
February 2013

Short read sequence typing (SRST): multi-locus sequence types from short reads.

BMC Genomics 2012 Jul 24;13:338. Epub 2012 Jul 24.

Department of Microbiology and Immunology, The University of Melbourne, Melbourne, Australia.

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http://dx.doi.org/10.1186/1471-2164-13-338DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3460743PMC
July 2012

SparSNP: fast and memory-efficient analysis of all SNPs for phenotype prediction.

BMC Bioinformatics 2012 May 10;13:88. Epub 2012 May 10.

NICTA Victoria Research Lab, Department of Computing and Information Systems, The University of Melbourne, Parkville 3010, Victoria, Australia.

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http://dx.doi.org/10.1186/1471-2105-13-88DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3483007PMC
May 2012

Genome-wide association studies and systems biology: together at last.

Trends Genet 2011 Dec 20;27(12):493-8. Epub 2011 Oct 20.

College of Chemistry and Chemical Engineering, Central South University, Changsha, Hunan Province, China.

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http://dx.doi.org/10.1016/j.tig.2011.09.002DOI Listing
December 2011

Genome-wide association study of migraine implicates a common susceptibility variant on 8q22.1.

Nat Genet 2010 Oct 29;42(10):869-73. Epub 2010 Aug 29.

Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Cambridge, UK.

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https://openaccess.leidenuniv.nl/bitstream/handle/1887/16353
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ftp://ftp.sanger.ac.uk/pub/resources/theses/sc14/chapter3.pd
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http://www.nature.com/doifinder/10.1038/ng.652
Publisher Site
http://dx.doi.org/10.1038/ng.652DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2948563PMC
October 2010

Integrating common and rare genetic variation in diverse human populations.

Nature 2010 Sep;467(7311):52-8

Broad Institute, 7 Cambridge Center, Cambridge, Massachusetts 02138, USA.

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http://dx.doi.org/10.1038/nature09298DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3173859PMC
September 2010

Genome-wide and fine-resolution association analysis of malaria in West Africa.

Nat Genet 2009 Jun 24;41(6):657-65. Epub 2009 May 24.

MRC Laboratories, Fajara, Banjul, Gambia.

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http://dx.doi.org/10.1038/ng.388DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2889040PMC
June 2009

Variants in MTNR1B influence fasting glucose levels.

Authors:
Inga Prokopenko Claudia Langenberg Jose C Florez Richa Saxena Nicole Soranzo Gudmar Thorleifsson Ruth J F Loos Alisa K Manning Anne U Jackson Yurii Aulchenko Simon C Potter Michael R Erdos Serena Sanna Jouke-Jan Hottenga Eleanor Wheeler Marika Kaakinen Valeriya Lyssenko Wei-Min Chen Kourosh Ahmadi Jacques S Beckmann Richard N Bergman Murielle Bochud Lori L Bonnycastle Thomas A Buchanan Antonio Cao Alessandra Cervino Lachlan Coin Francis S Collins Laura Crisponi Eco J C de Geus Abbas Dehghan Panos Deloukas Alex S F Doney Paul Elliott Nelson Freimer Vesela Gateva Christian Herder Albert Hofman Thomas E Hughes Sarah Hunt Thomas Illig Michael Inouye Bo Isomaa Toby Johnson Augustine Kong Maria Krestyaninova Johanna Kuusisto Markku Laakso Noha Lim Ulf Lindblad Cecilia M Lindgren Owen T McCann Karen L Mohlke Andrew D Morris Silvia Naitza Marco Orrù Colin N A Palmer Anneli Pouta Joshua Randall Wolfgang Rathmann Jouko Saramies Paul Scheet Laura J Scott Angelo Scuteri Stephen Sharp Eric Sijbrands Jan H Smit Kijoung Song Valgerdur Steinthorsdottir Heather M Stringham Tiinamaija Tuomi Jaakko Tuomilehto André G Uitterlinden Benjamin F Voight Dawn Waterworth H-Erich Wichmann Gonneke Willemsen Jacqueline C M Witteman Xin Yuan Jing Hua Zhao Eleftheria Zeggini David Schlessinger Manjinder Sandhu Dorret I Boomsma Manuela Uda Tim D Spector Brenda Wjh Penninx David Altshuler Peter Vollenweider Marjo Riitta Jarvelin Edward Lakatta Gerard Waeber Caroline S Fox Leena Peltonen Leif C Groop Vincent Mooser L Adrienne Cupples Unnur Thorsteinsdottir Michael Boehnke Inês Barroso Cornelia Van Duijn Josée Dupuis Richard M Watanabe Kari Stefansson Mark I McCarthy Nicholas J Wareham James B Meigs Gonçalo R Abecasis

Nat Genet 2009 Jan 7;41(1):77-81. Epub 2008 Dec 7.

[1] Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford OX3 7LJ, UK. [2] Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK. [3] These authors contributed equally to this work.

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http://dx.doi.org/10.1038/ng.290DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2682768PMC
January 2009

Common variants near MC4R are associated with fat mass, weight and risk of obesity.

Authors:
Ruth J F Loos Cecilia M Lindgren Shengxu Li Eleanor Wheeler Jing Hua Zhao Inga Prokopenko Michael Inouye Rachel M Freathy Antony P Attwood Jacques S Beckmann Sonja I Berndt Kevin B Jacobs Stephen J Chanock Richard B Hayes Sven Bergmann Amanda J Bennett Sheila A Bingham Murielle Bochud Morris Brown Stéphane Cauchi John M Connell Cyrus Cooper George Davey Smith Ian Day Christian Dina Subhajyoti De Emmanouil T Dermitzakis Alex S F Doney Katherine S Elliott Paul Elliott David M Evans I Sadaf Farooqi Philippe Froguel Jilur Ghori Christopher J Groves Rhian Gwilliam David Hadley Alistair S Hall Andrew T Hattersley Johannes Hebebrand Iris M Heid Claudia Lamina Christian Gieger Thomas Illig Thomas Meitinger H-Erich Wichmann Blanca Herrera Anke Hinney Sarah E Hunt Marjo-Riitta Jarvelin Toby Johnson Jennifer D M Jolley Fredrik Karpe Andrew Keniry Kay-Tee Khaw Robert N Luben Massimo Mangino Jonathan Marchini Wendy L McArdle Ralph McGinnis David Meyre Patricia B Munroe Andrew D Morris Andrew R Ness Matthew J Neville Alexandra C Nica Ken K Ong Stephen O'Rahilly Katharine R Owen Colin N A Palmer Konstantinos Papadakis Simon Potter Anneli Pouta Lu Qi Joshua C Randall Nigel W Rayner Susan M Ring Manjinder S Sandhu André Scherag Matthew A Sims Kijoung Song Nicole Soranzo Elizabeth K Speliotes Holly E Syddall Sarah A Teichmann Nicholas J Timpson Jonathan H Tobias Manuela Uda Carla I Ganz Vogel Chris Wallace Dawn M Waterworth Michael N Weedon Cristen J Willer Wraight Xin Yuan Eleftheria Zeggini Joel N Hirschhorn David P Strachan Willem H Ouwehand Mark J Caulfield Nilesh J Samani Timothy M Frayling Peter Vollenweider Gerard Waeber Vincent Mooser Panos Deloukas Mark I McCarthy Nicholas J Wareham Inês Barroso Kevin B Jacobs Stephen J Chanock Richard B Hayes Claudia Lamina Christian Gieger Thomas Illig Thomas Meitinger H-Erich Wichmann Peter Kraft Susan E Hankinson David J Hunter Frank B Hu Helen N Lyon Benjamin F Voight Martin Ridderstrale Leif Groop Paul Scheet Serena Sanna Goncalo R Abecasis Giuseppe Albai Ramaiah Nagaraja David Schlessinger Anne U Jackson Jaakko Tuomilehto Francis S Collins Michael Boehnke Karen L Mohlke

Nat Genet 2008 Jun 4;40(6):768-75. Epub 2008 May 4.

MRC Epidemiology Unit, Addenbrooke's Hospital, Cambridge CB2 0QQ, UK.

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http://dx.doi.org/10.1038/ng.140DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2669167PMC
June 2008

Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants.

Authors:
Paul R Burton David G Clayton Lon R Cardon Nick Craddock Panos Deloukas Audrey Duncanson Dominic P Kwiatkowski Mark I McCarthy Willem H Ouwehand Nilesh J Samani John A Todd Peter Donnelly Jeffrey C Barrett Dan Davison Doug Easton David M Evans Hin-Tak Leung Jonathan L Marchini Andrew P Morris Chris C A Spencer Martin D Tobin Antony P Attwood James P Boorman Barbara Cant Ursula Everson Judith M Hussey Jennifer D Jolley Alexandra S Knight Kerstin Koch Elizabeth Meech Sarah Nutland Christopher V Prowse Helen E Stevens Niall C Taylor Graham R Walters Neil M Walker Nicholas A Watkins Thilo Winzer Richard W Jones Wendy L McArdle Susan M Ring David P Strachan Marcus Pembrey Gerome Breen David St Clair Sian Caesar Katharine Gordon-Smith Lisa Jones Christine Fraser Elaine K Green Detelina Grozeva Marian L Hamshere Peter A Holmans Ian R Jones George Kirov Valentina Moskivina Ivan Nikolov Michael C O'Donovan Michael J Owen David A Collier Amanda Elkin Anne Farmer Richard Williamson Peter McGuffin Allan H Young I Nicol Ferrier Stephen G Ball Anthony J Balmforth Jennifer H Barrett Timothy D Bishop Mark M Iles Azhar Maqbool Nadira Yuldasheva Alistair S Hall Peter S Braund Richard J Dixon Massimo Mangino Suzanne Stevens John R Thompson Francesca Bredin Mark Tremelling Miles Parkes Hazel Drummond Charles W Lees Elaine R Nimmo Jack Satsangi Sheila A Fisher Alastair Forbes Cathryn M Lewis Clive M Onnie Natalie J Prescott Jeremy Sanderson Christopher G Matthew Jamie Barbour M Khalid Mohiuddin Catherine E Todhunter John C Mansfield Tariq Ahmad Fraser R Cummings Derek P Jewell John Webster Morris J Brown Mark G Lathrop John Connell Anna Dominiczak Carolina A Braga Marcano Beverley Burke Richard Dobson Johannie Gungadoo Kate L Lee Patricia B Munroe Stephen J Newhouse Abiodun Onipinla Chris Wallace Mingzhan Xue Mark Caulfield Martin Farrall Anne Barton Ian N Bruce Hannah Donovan Steve Eyre Paul D Gilbert Samantha L Hilder Anne M Hinks Sally L John Catherine Potter Alan J Silman Deborah P M Symmons Wendy Thomson Jane Worthington David B Dunger Barry Widmer Timothy M Frayling Rachel M Freathy Hana Lango John R B Perry Beverley M Shields Michael N Weedon Andrew T Hattersley Graham A Hitman Mark Walker Kate S Elliott Christopher J Groves Cecilia M Lindgren Nigel W Rayner Nicolas J Timpson Eleftheria Zeggini Melanie Newport Giorgio Sirugo Emily Lyons Fredrik Vannberg Adrian V S Hill Linda A Bradbury Claire Farrar Jennifer J Pointon Paul Wordsworth Matthew A Brown Jayne A Franklyn Joanne M Heward Matthew J Simmonds Stephen C L Gough Sheila Seal Michael R Stratton Nazneen Rahman Maria Ban An Goris Stephen J Sawcer Alastair Compston David Conway Muminatou Jallow Melanie Newport Giorgio Sirugo Kirk A Rockett Suzannah J Bumpstead Amy Chaney Kate Downes Mohammed J R Ghori Rhian Gwilliam Sarah E Hunt Michael Inouye Andrew Keniry Emma King Ralph McGinnis Simon Potter Rathi Ravindrarajah Pamela Whittaker Claire Widden David Withers Niall J Cardin Dan Davison Teresa Ferreira Joanne Pereira-Gale Ingeleif B Hallgrimsdo'ttir Bryan N Howie Zhan Su Yik Ying Teo Damjan Vukcevic David Bentley Matthew A Brown Alastair Compston Martin Farrall Alistair S Hall Andrew T Hattersley Adrian V S Hill Miles Parkes Marcus Pembrey Michael R Stratton Sarah L Mitchell Paul R Newby Oliver J Brand Jackie Carr-Smith Simon H S Pearce R McGinnis A Keniry P Deloukas John D Reveille Xiaodong Zhou Anne-Marie Sims Alison Dowling Jacqueline Taylor Tracy Doan John C Davis Laurie Savage Michael M Ward Thomas L Learch Michael H Weisman Mathew Brown

Nat Genet 2007 Nov 21;39(11):1329-37. Epub 2007 Oct 21.

Genetic Epidemiology Group, Department of Health Sciences, University of Leicester, Adrian Building, University Road, Leicester LE1 7RH, UK.

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http://dx.doi.org/10.1038/ng.2007.17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2680141PMC
November 2007

A genotype calling algorithm for the Illumina BeadArray platform.

Bioinformatics 2007 Oct 10;23(20):2741-6. Epub 2007 Sep 10.

Wellcome Trust Centre for Human Genetics, University of Oxford, Roosevelt Drive, Oxford OX3 7BN, UK.

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https://academic.oup.com/bioinformatics/article-lookup/doi/1
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http://dx.doi.org/10.1093/bioinformatics/btm443DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2666488PMC
October 2007

A knowledge-based scoring function based on residue triplets for protein structure prediction.

Protein Eng Des Sel 2006 May 13;19(5):187-93. Epub 2006 Mar 13.

Computational Genomics Group, Department of Microbiology, University of Washington School of Medicine, Seattle, WA 98195, USA.

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http://dx.doi.org/10.1093/protein/gzj018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5441915PMC
May 2006

NF1 transcriptional factor(s) is required for basal promoter activation of the human intestinal NaPi-IIb cotransporter gene.

Am J Physiol Gastrointest Liver Physiol 2005 Feb 30;288(2):G175-81. Epub 2004 Sep 30.

Department of Pediatrics, Steele Memorial Children's Research Center, University of Arizona Health Sciences Center, Tucson, AZ 85724, USA.

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http://dx.doi.org/10.1152/ajpgi.00396.2004DOI Listing
February 2005

Regulation of intestinal NaPi-IIb cotransporter gene expression by estrogen.

Am J Physiol Gastrointest Liver Physiol 2003 Dec 31;285(6):G1317-24. Epub 2003 Jul 31.

Department of Pediatrics, Steele Memorial Children's Research Center, University of Arizona Health Sciences Center, Tucson, Arizona 85724, USA.

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http://dx.doi.org/10.1152/ajpgi.00172.2003DOI Listing
December 2003

Transcriptional regulation of the human NaPi-IIb cotransporter by EGF in Caco-2 cells involves c-myb.

Am J Physiol Cell Physiol 2003 May 15;284(5):C1262-71. Epub 2003 Jan 15.

Department of Pediatrics, Steele Memorial Children's Research Center, University of Arizona Health Sciences Center, Tucson, Arizona 85724, USA.

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http://dx.doi.org/10.1152/ajpcell.00456.2002DOI Listing
May 2003

Functional characterization of the human intestinal NaPi-IIb cotransporter in hamster fibroblasts and Xenopus oocytes.

Biochim Biophys Acta 2002 Dec;1567(1-2):97-105

Department of Pediatrics, Steele Memorial Children's Research Center, University of Arizona Health Sciences Center, 1501 N. Campbell Avenue, Tucson, AZ 85274, USA.

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http://dx.doi.org/10.1016/s0005-2736(02)00604-1DOI Listing
December 2002