Michael Huddleston

Michael Huddleston

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Michael Huddleston

Michael Huddleston

Publications by authors named "Michael Huddleston"

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16Publications

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A Scalable Platform for Producing Recombinant Nucleosomes with Codified Histone Methyltransferase Substrate Preferences.

Protein Expr Purif 2019 Dec 12;164:105455. Epub 2019 Jul 12.

Janssen Pharmaceutical Companies of Johnson and Johnson, Philadelphia, PA, USA.

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http://dx.doi.org/10.1016/j.pep.2019.105455DOI Listing
December 2019

Transition state for the NSD2-catalyzed methylation of histone H3 lysine 36.

Proc Natl Acad Sci U S A 2016 Feb 19;113(5):1197-201. Epub 2016 Jan 19.

Department of Biochemistry, Albert Einstein College of Medicine of Yeshiva University, Bronx, NY 10461;

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http://dx.doi.org/10.1073/pnas.1521036113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4747696PMC
February 2016

An optimized platform for hydrophilic interaction chromatography-immobilized metal affinity chromatography enables deep coverage of the rat liver phosphoproteome.

J Proteome Res 2015 Feb 26;14(2):997-1009. Epub 2015 Jan 26.

Proteomics and Biological Mass Spectrometry Laboratory, GlaxoSmithKline , Collegeville, Pennsylvania 19426, United States.

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http://dx.doi.org/10.1021/pr501025eDOI Listing
February 2015

Dbf2-Mob1 drives relocalization of protein phosphatase Cdc14 to the cytoplasm during exit from mitosis.

J Cell Biol 2009 Feb 16;184(4):527-39. Epub 2009 Feb 16.

Division of Biology, California Institute of Technology, Pasadena, CA 91125, USA.

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http://www.jcb.org/lookup/doi/10.1083/jcb.200812022
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http://dx.doi.org/10.1083/jcb.200812022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2654127PMC
February 2009

A quantitative results-driven approach to analyzing multisite protein phosphorylation: the phosphate-dependent phosphorylation profile of the transcription factor Pho4.

Mol Cell Proteomics 2006 Nov 6;5(11):2019-30. Epub 2006 Jul 6.

Proteomics and Biological Mass Spectrometry Laboratory, Department of Computational, Analytical and Structural Sciences, GlaxoSmithKline, King of Prussia, Pennsylvania 19406, USA.

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http://www.mcponline.org/lookup/doi/10.1074/mcp.M600238-MCP2
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http://dx.doi.org/10.1074/mcp.M600238-MCP200DOI Listing
November 2006

Mapping posttranslational modifications of proteins by MS-based selective detection: application to phosphoproteomics.

Methods Enzymol 2005 ;405:82-115

GlaxoSmithKline Pharmaceuticals, King of Prussia, Pennsylvania, USA.

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http://dx.doi.org/10.1016/S0076-6879(05)05005-6DOI Listing
February 2006

Identification of tyrosine residues on ELMO1 that are phosphorylated by the Src-family kinase Hck.

Biochemistry 2005 Jun;44(24):8841-9

Department of Physiology and Biophysics, School of Medicine, State University of New York at Stony Brook, Stony Brook, New York 11794-8661, USA.

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http://dx.doi.org/10.1021/bi0500832DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2441568PMC
June 2005

Comparative phosphorylation site mapping from gel-derived proteins using a multidimensional ES/MS-based approach.

Methods Mol Biol 2004 ;284:91-110

Proteomics and Biological Mass Spectrometry Laboratory, Department of Computational, Analytical and Structural Sciences, GlaxoSmithKline, King of Prussia, PA, USA.

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http://link.springer.com/10.1385/1-59259-816-1:091
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http://dx.doi.org/10.1385/1-59259-816-1:091DOI Listing
September 2004

Mistranslational errors associated with the rare arginine codon CGG in Escherichia coli.

Protein Expr Purif 2003 Feb;27(2):365-74

Department of Gene Expression and Protein Biochemistry, GlaxoSmithKline, 709 Swedeland Road, King of Prussia, PA 19406, USA.

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February 2003

Mapping phosphorylation sites in proteins by mass spectrometry.

Methods Enzymol 2002 ;351:279-96

Rockefeller University, New York, New York 10021, USA.

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http://dx.doi.org/10.1016/s0076-6879(02)51853-xDOI Listing
July 2002

Improved sensitivity for phosphopeptide mapping using capillary column HPLC and microionspray mass spectrometry: comparative phosphorylation site mapping from gel-derived proteins.

Anal Chem 2002 Jul;74(13):3221-31

Department of Computational, Analytical and Structural Sciences, GlaxoSmithKline, King of Prussia, Pennsylvania 19406, USA.

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http://dx.doi.org/10.1021/ac025538xDOI Listing
July 2002

Cdc5 influences phosphorylation of Net1 and disassembly of the RENT complex.

BMC Mol Biol 2002 Apr 17;3. Epub 2002 Apr 17.

Division of Biology, California Institute of Technology, Pasadena, California 91125, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC113746PMC
April 2002

Mass spectrometry-based methods for phosphorylation site mapping of hyperphosphorylated proteins applied to Net1, a regulator of exit from mitosis in yeast.

Mol Cell Proteomics 2002 Mar;1(3):186-96

Proteomics and Biological Mass Spectrometry, GlaxoSmithKline, King of Prussia, Pennsylvania 19406, USA.

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http://dx.doi.org/10.1074/mcp.m100032-mcp200DOI Listing
March 2002