Publications by authors named "Michael Hallett"

83Publications

Prisoners Helping Prisoners Change: A Study of Inmate Field Ministers Within Texas Prisons.

Int J Offender Ther Comp Criminol 2020 04 5;64(5):470-497. Epub 2019 Sep 5.

Minnesota Department of Corrections, St. Paul, Minnesota, USA.

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April 2020

The time-varying effect of radiotherapy after breast-conserving surgery for DCIS.

Breast Cancer Res Treat 2019 Nov 31;178(1):221-230. Epub 2019 Jul 31.

Department of Radiation Oncology, Toronto, ON, Canada.

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November 2019

The Complex Subtype-Dependent Role of Connexin 43 (GJA1) in Breast Cancer.

Int J Mol Sci 2018 Feb 28;19(3). Epub 2018 Feb 28.

INRS-Institut Armand-Frappier, Laval, QC H7V 1B7, Canada.

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February 2018

Identification of Interacting Stromal Axes in Triple-Negative Breast Cancer.

Cancer Res 2017 09 26;77(17):4673-4683. Epub 2017 Jun 26.

Goodman Cancer Research Centre, McGill University, Montreal, Quebec, Canada.

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September 2017

Discovery of Stromal Regulatory Networks that Suppress Ras-Sensitized Epithelial Cell Proliferation.

Dev Cell 2017 05;41(4):392-407.e6

Solid Tumor Biology Program, Comprehensive Cancer Center, The Ohio State University, Columbus, OH 43210, USA; Department of Molecular Genetics, The Ohio State University, 484 West 12th Avenue, Columbus, OH 43210, USA; Department of Cancer Biology and Genetics, McGill University, Montreal, QC H3A 1A1, Canada; Hollings Cancer Center, Medical University of South Carolina, Hollings Cancer Center 124J, 86 Jonathan Lucas Street, Charleston, SC 29425, USA. Electronic address:

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May 2017

A 12-gene signature to distinguish colon cancer patients with better clinical outcome following treatment with 5-fluorouracil or FOLFIRI.

J Pathol Clin Res 2015 Jul 9;1(3):160-72. Epub 2015 Apr 9.

Department of molecular biology medical biochemistry and pathology Laval University Centre de Recherche du CHU de Québec, Centre Hospitalier de l'Université Laval Québec Canada.

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July 2015

Molecular Features of Subtype-Specific Progression from Ductal Carcinoma In Situ to Invasive Breast Cancer.

Cell Rep 2016 07 7;16(4):1166-1179. Epub 2016 Jul 7.

Institute for Cancer Research and Department of Cancer Genetics, Oslo University Hospital, The Norwegian Radium Hospital, 0424 Oslo, Norway; K.G. Jebsen Centre for Breast Cancer Research, Institute for Clinical Medicine, University of Oslo, 0318 Oslo, Norway. Electronic address:

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July 2016

Chordin-Like 1 Suppresses Bone Morphogenetic Protein 4-Induced Breast Cancer Cell Migration and Invasion.

Mol Cell Biol 2016 05 2;36(10):1509-25. Epub 2016 May 2.

Goodman Cancer Research Centre, McGill University, Montréal, Québec, Canada Department of Biochemistry, McGill University, Montréal, Québec, Canada Department of Medicine, McGill University, Montréal, Québec, Canada

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May 2016

Structural and Functional Characterization of a Caenorhabditis elegans Genetic Interaction Network within Pathways.

PLoS Comput Biol 2016 Feb 12;12(2):e1004738. Epub 2016 Feb 12.

Department of Chemistry, Université du Québec à Montréal, Montréal, Québec, Canada.

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February 2016

STAT3 Establishes an Immunosuppressive Microenvironment during the Early Stages of Breast Carcinogenesis to Promote Tumor Growth and Metastasis.

Cancer Res 2016 Mar 30;76(6):1416-28. Epub 2015 Dec 30.

Goodman Cancer Centre, McGill University, Montreal, Quebec, Canada. Departments of Biochemistry, McGill University, Montreal, Quebec, Canada.

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March 2016

Disruption of histone methylation in developing sperm impairs offspring health transgenerationally.

Science 2015 Nov 8;350(6261):aab2006. Epub 2015 Oct 8.

Department of Pharmacology and Therapeutics, Faculty of Medicine, McGill University, Montreal, Quebec, Canada. Department of Animal Science, Faculty of Agricultural and Environmental Sciences, McGill University, Montreal, Quebec, Canada.

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November 2015

"First Stop Dying".

Int J Offender Ther Comp Criminol 2017 Mar 28;61(4):445-463. Epub 2016 Jul 28.

3 Minnesota Department of Corrections, St. Paul, USA.

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March 2017

Role of DNA methylation in the nucleus accumbens in incubation of cocaine craving.

J Neurosci 2015 May;35(21):8042-58

Leslie and Susan Gonda (Goldschmied) Multidisciplinary Brain Research Center, Bar-Ilan University, Ramat Gan 52900, Israel, Mina and Everard Goodman Faculty of Life Sciences, Bar-Ilan University, Ramat-Gan 52900, Israel,

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May 2015

A functional in vitro model of heterotypic interactions reveals a role for interferon-positive carcinoma associated fibroblasts in breast cancer.

BMC Cancer 2015 Mar 15;15:130. Epub 2015 Mar 15.

Lady Davis Institute for Medical Research, Sir Mortimer B. Davis Jewish General Hospital, Montreal, Canada.

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March 2015

Absolute assignment of breast cancer intrinsic molecular subtype.

J Natl Cancer Inst 2015 Jan 4;107(1):357. Epub 2014 Dec 4.

Centre for Bioinformatics, McGill University, Montreal, Quebec, H3G 0B1, Canada (ERP, MTH); The Rosalind and Morris Goodman Cancer Research Centre, McGill University, Montreal, Quebec, H3A 1A3, Canada (ERP, MTH); Department of Biochemistry, McGill University, Montreal, Quebec, H3G 1Y6, Canada (ERP, MTH).

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January 2015

The prognostic ease and difficulty of invasive breast carcinoma.

Cell Rep 2014 Oct 2;9(1):129-142. Epub 2014 Oct 2.

The Rosalind and Morris Goodman Cancer Research Centre, McGill University, Montreal, QC H3A1A3, Canada; Centre for Bioinformatics, McGill University, Montreal, QC H3G0B1, Canada; Department of Biochemistry, McGill University, Montreal, QC H3G1Y6, Canada. Electronic address:

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October 2014

Autocrine Activation of the Wnt/β-Catenin Pathway by CUX1 and GLIS1 in Breast Cancers.

Biol Open 2014 Sep 12;3(10):937-46. Epub 2014 Sep 12.

Goodman Cancer Research Centre, McGill University, Montreal, QC H3A 1A3, Canada Department of Biochemistry, McGill University, Montreal, QC H3G 1Y6, Canada Department of Medicine, McGill University, Montreal, QC H3A 1A1, Canada Department of Oncology, McGill University, Montreal, QC H2W 1S6, Canada

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September 2014

Synergistic effects of combined DNA methyltransferase inhibition and MBD2 depletion on breast cancer cells; MBD2 depletion blocks 5-aza-2'-deoxycytidine-triggered invasiveness.

Carcinogenesis 2014 Nov 1;35(11):2436-46. Epub 2014 Sep 1.

Department of Pharmacology and Therapeutics, McGill University and Sackler Program for Epigenetics and Developmental Psychobiology, McGill University, 3655 Promenade Sir William Osler, Montreal, Quebec H3G 1Y6, Canada,

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November 2014

p66ShcA promotes breast cancer plasticity by inducing an epithelial-to-mesenchymal transition.

Mol Cell Biol 2014 Oct 28;34(19):3689-701. Epub 2014 Jul 28.

Lady Davis Institute for Medical Research, Montreal, Quebec, Canada Department of Oncology, McGill University, Montreal, Quebec, Canada

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October 2014

Genome-wide study of hypomethylated and induced genes in patients with liver cancer unravels novel anticancer targets.

Clin Cancer Res 2014 Jun 24;20(12):3118-32. Epub 2014 Apr 24.

Authors' Affiliations: Departments of Pharmacology and Therapeutics and Medicine, McGill University Health Centre, Montreal; McGill Centre for Bioinformatics; and Sackler program for Psychobiology and Epigenetics at McGill University, Montreal, Quebec, Canada; Department of Nutrition Science, Purdue University, West Lafayette, Indiana; Shanghai-MOST Key Laboratory for Disease and Health Genomics, Chinese National Human Genome Center at Shanghai, Shanghai, China; Department of Hepatology, Bangabandhu Sheikh Mujib Medical University; International Centre for Diarrhoeal Diseases Research, Bangladesh (icddr,b), Dhaka, Dhaka District, Bangladesh; Department of Medical Sciences, Toshiba General Hospital, Tokyo, Kanto, Japan; and Department of Pathology, Fatima Memorial Hospital College of Medicine and Dentistry Lahore, PakistanAuthors' Affiliations: Departments of Pharmacology and Therapeutics and Medicine, McGill University Health Centre, Montreal; McGill Centre for Bioinformatics; and Sackler program for Psychobiology and Epigenetics at McGill University, Montreal, Quebec, Canada; Department of Nutrition Science, Purdue University, West Lafayette, Indiana; Shanghai-MOST Key Laboratory for Disease and Health Genomics, Chinese National Human Genome Center at Shanghai, Shanghai, China; Department of Hepatology, Bangabandhu Sheikh Mujib Medical University; International Centre for Diarrhoeal Diseases Research, Bangladesh (icddr,b), Dhaka, Dhaka District, Bangladesh; Department of Medical Sciences, Toshiba General Hospital, Tokyo, Kanto, Japan; and Department of Pathology, Fatima Memorial Hospital College of Medicine and Dentistry Lahore, Pakistan

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June 2014

Association of childhood chronic physical aggression with a DNA methylation signature in adult human T cells.

PLoS One 2014 1;9(4):e89839. Epub 2014 Apr 1.

Department of Pharmacology & Therapeutics, McGill University, Montreal, Quebec, Canada; Sackler Program for Epigenetics and Psychobiology, McGill University, Montreal, Quebec, Canada.

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December 2015

Religiously Motivated Desistance: An Exploratory Study.

Int J Offender Ther Comp Criminol 2015 Jul 16;59(8):855-72. Epub 2014 Feb 16.

Prisoners of Christ, Jacksonville, FL, USA.

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July 2015

DNA methylation signature of childhood chronic physical aggression in T cells of both men and women.

PLoS One 2014 24;9(1):e86822. Epub 2014 Jan 24.

Department of Pharmacology & Therapeutics, McGill University, Montreal, Quebec, Canada ; Sackler Program for Epigenetics and Psychobiology, McGill University, Montreal, Quebec, Canada.

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February 2015

Naive CD4 T-cell activation identifies MS patients having rapid transition to progressive MS.

Neurology 2014 Feb 22;82(8):681-90. Epub 2014 Jan 22.

From Neuroscience (E.Z., L.F.-G.), Department of Pathology (D.G.H.), and McGill Centre for Bioinformatics (M.H.), McGill University, Montreal; Neurology (J.A., A.B.-O., Y.L.), Montreal Neurological Hospital, Montreal, Canada; and Neurology (S.B.), UCSF, San Francisco, CA.

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February 2014

Differential DNA methylation regions in cytokine and transcription factor genomic loci associate with childhood physical aggression.

PLoS One 2013 19;8(8):e71691. Epub 2013 Aug 19.

Department of Pharmacology and Therapeutics, McGill University, Montreal, Quebec, Canada ; Research Unit on Children's Psycho-Social Maladjustment and Ste-Justine Hospital Research Center, University of Montreal, Montreal, Quebec, Canada ; Sackler Program for Epigenetics and Psychobiology, McGill University, Montreal, Quebec, Canada.

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April 2014

Transcription onset of genes critical in liver carcinogenesis is epigenetically regulated by methylated DNA-binding protein MBD2.

Carcinogenesis 2013 Dec 16;34(12):2738-49. Epub 2013 Aug 16.

Department of Pharmacology and Therapeutics, McGill University, Montreal, Quebec H3G 1Y6, Canada.

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December 2013

The ShcA PTB domain functions as a biological sensor of phosphotyrosine signaling during breast cancer progression.

Cancer Res 2013 Jul 21;73(14):4521-32. Epub 2013 May 21.

Lady Davis Institute for Medical Research, McGill Centre for Bioinformatics, McGill University, Goodman Cancer Research Centre, Montreal, Quebec, Canada.

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July 2013

Glucocorticoid programming of the fetal male hippocampal epigenome.

Endocrinology 2013 Mar 6;154(3):1168-80. Epub 2013 Feb 6.

Department Pharmacology & Therapeutics, McGill University, Montreal, Quebec, Canada H3G1Y6.

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March 2013

The signature of maternal rearing in the methylome in rhesus macaque prefrontal cortex and T cells.

J Neurosci 2012 Oct;32(44):15626-42

Sackler Program for Epigenetics and Developmental Psychobiology, Department of Pharmacology and Therapeutics, McGill University, Montreal, Quebec, Canada, H3A 0G4.

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October 2012

Conserved epigenetic sensitivity to early life experience in the rat and human hippocampus.

Proc Natl Acad Sci U S A 2012 Oct 8;109 Suppl 2:17266-72. Epub 2012 Oct 8.

Sackler Program for Epigenetics and Developmental Psychobiology at McGill University, Department of Pharmacology and Therapeutics, McGill University, Montreal, QC, Canada.

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October 2012

Associations with early-life socio-economic position in adult DNA methylation.

Int J Epidemiol 2012 Feb 20;41(1):62-74. Epub 2011 Oct 20.

Sackler Program for Epigenetics & Developmental Psychobiology, McGill University, Montreal, Quebec, Canada.

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February 2012

Definition of the landscape of promoter DNA hypomethylation in liver cancer.

Cancer Res 2011 Sep 11;71(17):5891-903. Epub 2011 Jul 11.

Department of Pharmacology and Therapeutics, McGill Centre for Bioinformatics, Montreal, Canada.

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September 2011

Intracellular eukaryotic parasites have a distinct unfolded protein response.

PLoS One 2011 Apr 29;6(4):e19118. Epub 2011 Apr 29.

McGill Centre for Bioinformatics, McGill University, Montréal, Québec, Canada.

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April 2011

Broad epigenetic signature of maternal care in the brain of adult rats.

PLoS One 2011 Feb 28;6(2):e14739. Epub 2011 Feb 28.

Douglas Mental Health University Institute, Montreal, Quebec, Canada.

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February 2011

Cut homeobox 1 causes chromosomal instability by promoting bipolar division after cytokinesis failure.

Proc Natl Acad Sci U S A 2011 Feb 18;108(5):1949-54. Epub 2011 Jan 18.

Department of Biochemistry Oncology, and Medicine, McGill University, Rosalind and Morris Goodman Cancer Research Centre, Montreal, QC, Canada.

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February 2011

Simultaneous identification of duplications and lateral gene transfers.

IEEE/ACM Trans Comput Biol Bioinform 2011 Mar-Apr;8(2):517-35

KTH Royal Institute of Technology, Department of Computational Biology, Stockholm, Sweden.

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June 2011

Stromal retinoic acid receptor beta promotes mammary gland tumorigenesis.

Proc Natl Acad Sci U S A 2011 Jan 27;108(2):774-9. Epub 2010 Dec 27.

Goodman Cancer Research Centre, McGill University, Montreal, QC, Canada H3A 1A3.

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January 2011

ADAM10 releases a soluble form of the GPNMB/Osteoactivin extracellular domain with angiogenic properties.

PLoS One 2010 Aug 10;5(8):e12093. Epub 2010 Aug 10.

Goodman Cancer Research Centre, McGill University, Montreal, Quebec, Canada.

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August 2010

Molecular diversity in ductal carcinoma in situ (DCIS) and early invasive breast cancer.

Mol Oncol 2010 Aug 26;4(4):357-68. Epub 2010 Jun 26.

Department of Genetics, Institute for Cancer Research, Oslo University Hospital Radiumhospitalet, Montebello, 0310 Oslo, Norway.

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August 2010

A trade-off between sample complexity and computational complexity in learning Boolean networks from time-series data.

IEEE/ACM Trans Comput Biol Bioinform 2010 Jan-Mar;7(1):118-25

McGill University, 3480 University St., Montreal, Quebec, Canada.

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May 2010

Chemogenomic profiling predicts antifungal synergies.

Mol Syst Biol 2009 22;5:338. Epub 2009 Dec 22.

Department of Biochemistry, Faculty of Medicine, McGill University, Montréal, Québec, Canada.

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February 2010

CrkII transgene induces atypical mammary gland development and tumorigenesis.

Am J Pathol 2010 Jan 11;176(1):446-60. Epub 2009 Dec 11.

Departments of Biochemistry, Rosalind and Morris Goodman Cancer Centre, McGill University, Montréal, QC H3A 1A3, Canada.

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January 2010

Identification of a Stat3-dependent transcription regulatory network involved in metastatic progression.

Cancer Res 2009 Sep 18;69(17):6823-30. Epub 2009 Aug 18.

Goodman Cancer Centre, McGill University, Montreal, Quebec, Canada.

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September 2009

Genome-wide identification of direct target genes implicates estrogen-related receptor alpha as a determinant of breast cancer heterogeneity.

Cancer Res 2009 Aug 21;69(15):6149-57. Epub 2009 Jul 21.

Rosalind and Morris Goodman Cancer Centre, Department of Biochemistry, McGill University, Montreal, Quebec, Canada.

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August 2009

[The tumor microenvironment: a new tool to predict breast cancer outcome].

Med Sci (Paris) 2009 May;25(5):439-41

McGill Center for Bioinformatics, Université McGill, Montréal, Québec, Canada.

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May 2009

DNA demethylation induced by the methyl-CpG-binding domain protein MBD3.

Gene 2008 Sep 4;420(2):99-106. Epub 2008 Jul 4.

McGill University, Department of Pharmacology and Therapeutics, Montréal, Québec, Canada H3G 1Y6.

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September 2008

Stromal gene expression predicts clinical outcome in breast cancer.

Nat Med 2008 May 27;14(5):518-27. Epub 2008 Apr 27.

McGill Centre for Bioinformatics, 3775 University Street, McGill University, Québec H3A 2B4, Canada.

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May 2008

Osteoactivin promotes breast cancer metastasis to bone.

Mol Cancer Res 2007 Oct;5(10):1001-14

Department of Medicine, McGill University, Montreal, Quebec, Canada.

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October 2007

Tools for visually exploring biological networks.

Bioinformatics 2007 Oct 25;23(20):2651-9. Epub 2007 Aug 25.

McGill Centre for Bioinformatics, 3775 University Street, Montreal, QCH3A 2B4, Canada.

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October 2007

Strain-dependent pulmonary gene expression profiles of a cystic fibrosis mouse model.

Physiol Genomics 2006 Apr;25(2):336-45

Department of Medicine, McGill University, Montreal, Quebec, Canada.

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April 2006

Refining protein subcellular localization.

PLoS Comput Biol 2005 Nov 25;1(6):e66. Epub 2005 Nov 25.

McGill Center for Bioinformatics, McGill University, Montreal, Quebec, Canada.

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November 2005

Identifying regulatory subnetworks for a set of genes.

Mol Cell Proteomics 2005 May 18;4(5):683-92. Epub 2005 Feb 18.

McGill Centre for Bioinformatics, 3775 University Street, Montreal H3A 2B4, Canada.

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May 2005

Predicting subcellular localization via protein motif co-occurrence.

Genome Res 2004 Oct;14(10A):1957-66

McGill Center for Bioinformatics, McGill University, Montreal, Quebec H3A 2B4, Canada.

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October 2004

DePIE: Designing Primers for Protein Interaction Experiments.

Nucleic Acids Res 2003 Jul;31(13):3755-7

McGill Centre for Bioinformatics, School of Computer Science, McGill University, 3775 University Street, Montreal, QC, Canada H3A 2B4.

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July 2003