Michael Hahne

Michael Hahne

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Michael Hahne

Michael Hahne

Publications by authors named "Michael Hahne"

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APRIL Induces a Novel Subset of IgA Regulatory B Cells That Suppress Inflammation via Expression of IL-10 and PD-L1.

Front Immunol 2019 14;10:1368. Epub 2019 Jun 14.

Department of Clinical Immunology and Rheumatology, Amsterdam Rheumatology and Immunology Centre, Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands.

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http://dx.doi.org/10.3389/fimmu.2019.01368DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6587076PMC
June 2019

Mixed signals from the cell's antennae: primary cilia in cancer.

EMBO Rep 2018 11 22;19(11). Epub 2018 Oct 22.

IGMM, CNRS, University of Montpellier, Montpellier, France

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http://dx.doi.org/10.15252/embr.201846589DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6216287PMC
November 2018

A New Animal Model of Gastric Lymphomagenesis: APRIL Transgenic Mice Infected by Helicobacter Species.

Am J Pathol 2017 Jul 29;187(7):1473-1484. Epub 2017 Apr 29.

INSERM UMR1053, Bordeaux Research in Translational Oncology, Bordeaux, France. Electronic address:

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http://dx.doi.org/10.1016/j.ajpath.2017.03.004DOI Listing
July 2017

Th17 and regulatory T cells are increased in blood of patients with birdshot chorioretinopathy.

Acta Ophthalmol 2017 Mar 24;95(2):e161-e163. Epub 2016 Mar 24.

Molecular Genetic Institute of Montpellier, CNRS, UMR5535, Montpellier, France.

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http://dx.doi.org/10.1111/aos.12949DOI Listing
March 2017

A proliferation inducing ligand (APRIL) promotes IL-10 production and regulatory functions of human B cells.

J Autoimmun 2016 09 29;73:64-72. Epub 2016 Jun 29.

Department of Rheumatology, Lapeyronie Hospital and Montpellier University, Montpellier, France; UMR5535, IGMM, CNRS, Montpellier, France. Electronic address:

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http://dx.doi.org/10.1016/j.jaut.2016.06.002DOI Listing
September 2016

SNX9 promotes metastasis by enhancing cancer cell invasion via differential regulation of RhoGTPases.

Mol Biol Cell 2016 Mar 9. Epub 2016 Mar 9.

Department of Cell Biology, The University of Texas Southwestern Medical Center, Dallas. 6000 Harry Hines Blvd. Dallas, TX 75390-9039

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http://dx.doi.org/10.1091/mbc.E16-02-0101DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4850029PMC
March 2016

In Silico Identification of Novel APRIL Peptide Antagonists and Binding Insights by Molecular Modeling and Immunosorbent Assays.

Protein Pept Lett 2015 ;22(5):432-42

Laboratorio de Pesquisas sobre o Timo. Instituto Oswaldo Cruz. Fundacao Oswaldo Cruz (FIOCRUZ), Manguinhos, Rio de Janeiro, RJ, Brazil, 21041-250.

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http://dx.doi.org/10.2174/0929866522666150302124953DOI Listing
February 2016

Targeting the Fas/FasL system in Rheumatoid Arthritis therapy: Promising or risky?

Cytokine 2015 Oct 4;75(2):228-33. Epub 2014 Dec 4.

Institut de Génétique Moléculaire de Montpellier, Université Montpellier Sud de France, 1919 route de Mende, CNRS, UMR5535, Montpellier, France; Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.cyto.2014.10.004DOI Listing
October 2015

Cyclin A2 modulates EMT via β-catenin and phospholipase C pathways.

Carcinogenesis 2015 Aug 19;36(8):914-24. Epub 2015 May 19.

Institut de Génétique Moléculaire de Montpellier, CNRS, France-Université Montpellier 2, France-Université Montpellier 1, Montpellier, France,

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http://dx.doi.org/10.1093/carcin/bgv069DOI Listing
August 2015

Osteoprotegerin and tumor necrosis factor-related apoptosis-inducing ligand as prognostic factors in rheumatoid arthritis: results from the ESPOIR cohort.

Arthritis Res Ther 2015 Jul 29;17:193. Epub 2015 Jul 29.

Department of Rheumatology, Lapeyronie Hospital, Montpellier University, 371 avenue doyen Giraud, 34295, Montpellier, France.

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http://dx.doi.org/10.1186/s13075-015-0705-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4518710PMC
July 2015

High levels of natural killer cells are associated with response to tocilizumab in patients with severe rheumatoid arthritis.

Rheumatology (Oxford) 2015 Apr 16;54(4):601-8. Epub 2014 Sep 16.

Department of Rheumatology, Lapeyronie Hospital and Montpellier University I, TNF-alpha Laboratory, UMR5535, CNRS, Clinical Investigation Center, University Hospital of Montpellier and INSERM, CIC 1001, Montpellier, France, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands and Institut de Génétique Moléculaire de Montpellier, UMR5535, CNRS, Université Montpellier Sud de France, France. Department of Rheumatology, Lapeyronie Hospital and Montpellier University I, TNF-alpha Laboratory, UMR5535, CNRS, Clinical Investigation Center, University Hospital of Montpellier and INSERM, CIC 1001, Montpellier, France, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands and Institut de Génétique Moléculaire de Montpellier, UMR5535, CNRS, Université Montpellier Sud de France, France.

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http://dx.doi.org/10.1093/rheumatology/keu363DOI Listing
April 2015

Distinct effects of soluble and membrane-bound fas ligand on fibroblast-like synoviocytes from rheumatoid arthritis patients.

Arthritis Rheumatol 2014 Dec;66(12):3289-99

Institut de Génétique Moléculaire de Montpellier, CNRS, UMR5535, Université Montpellier Sud de France, Montpellier 1 University, and Lapeyronie Teaching Hospital, Montpellier, France.

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http://dx.doi.org/10.1002/art.38806DOI Listing
December 2014

Regulatory B10 cells are decreased in patients with rheumatoid arthritis and are inversely correlated with disease activity.

Arthritis Rheumatol 2014 Aug;66(8):2037-46

Lapeyronie Hospital, Montpellier 1 University, and Institute of Molecular Genetics of Montpellier, UMR5535, CNRS, Montpellier, France.

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http://dx.doi.org/10.1002/art.38666DOI Listing
August 2014

The TNF family member APRIL dampens collagen-induced arthritis.

Ann Rheum Dis 2013 Aug 24;72(8):1367-74. Epub 2012 Nov 24.

Institut de Génétique Moléculaire de Montpellier, CNRS, Montpellier, France.

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http://dx.doi.org/10.1136/annrheumdis-2012-202382DOI Listing
August 2013

The two directions of TNF-related apoptosis-inducing ligand in rheumatoid arthritis.

Cytokine 2013 Aug 4;63(2):81-90. Epub 2013 May 4.

Institut de Génétique Moléculaire de Montpellier, CNRS, UMR 5535, Montpellier, France.

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http://dx.doi.org/10.1016/j.cyto.2013.04.011DOI Listing
August 2013

Lymphotoxin α revisited: general features and implications in rheumatoid arthritis.

Arthritis Res Ther 2011 Jul 26;13(4):232. Epub 2011 Jul 26.

Institut de Génétique Moléculaire de Montpellier CNRS-UMR 5535, 1919 Route de Mende, 34293 Montpellier, Cedex 5, France.

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http://dx.doi.org/10.1186/ar3376DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3239340PMC
July 2011

Mechanisms and clinical relevance of TRAIL-triggered responses in the synovial fibroblasts of patients with rheumatoid arthritis.

Arthritis Rheum 2011 Apr;63(4):904-13

Institut de Génétique Moléculaire de Montpellier, Université Montpellier I, Montpellier, France.

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http://dx.doi.org/10.1002/art.30181DOI Listing
April 2011

Lymphotoxin α stimulates proliferation and pro-inflammatory cytokine secretion of rheumatoid arthritis synovial fibroblasts.

Cytokine 2011 Feb 15;53(2):207-14. Epub 2010 Dec 15.

Institut de Génétique Moléculaire de Montpellier, 1919 route de Mende, CNRS UMR5535, Montpellier, France.

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http://dx.doi.org/10.1016/j.cyto.2010.10.010DOI Listing
February 2011

APRIL in B-cell malignancies and autoimmunity.

Results Probl Cell Differ 2009 ;49:161-82

Lab of Exp. Oncology and Radiobiology, Center for Experimental Molecular Medicine, Academic Medical Center, University of Amsterdam, Room G1-114, 1105 AZ, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1007/400_2008_19DOI Listing
March 2010

The proteoglycan (heparan sulfate proteoglycan) binding domain of APRIL serves as a platform for ligand multimerization and cross-linking.

FASEB J 2009 May 13;23(5):1584-95. Epub 2009 Jan 13.

Laboratory of Experimental Oncology and Radiobiology, Center for Experimental Molecular Medicine, University of Amsterdam, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1096/fj.08-124669DOI Listing
May 2009

"APRIL hath put a spring of youth in everything": Relevance of APRIL for survival.

J Cell Physiol 2009 Jan;218(1):1-8

LEXOR (Lab of Experimental Oncology and Radiobiology), Center for Experimental Molecular Medicine, Academic Medical Center (AMC), University of Amsterdam, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1002/jcp.21561DOI Listing
January 2009

Blocking the APRIL circuit enhances acute myeloid leukemia cell chemosensitivity.

Haematologica 2008 Dec 6;93(12):1899-902. Epub 2008 Oct 6.

Dept. of Hematology, Oncology and Molecular Medicine, Istituto Superiore Sanità, Rome, Italy.

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http://dx.doi.org/10.3324/haematol.13035DOI Listing
December 2008

The expanding role of APRIL in cancer and immunity.

Curr Mol Med 2008 Dec;8(8):829-44

Centro Nacional de Biotecnologia/CSIC, UAM Campus de Cantoblanco, 28049 Madrid, Spain.

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http://dx.doi.org/10.2174/156652408786733711DOI Listing
December 2008

Thymus-independent class switch recombination is affected by APRIL.

Immunol Cell Biol 2008 Aug-Sep;86(6):530-4. Epub 2008 Mar 25.

Laboratory of Experimental Oncology and Radiobiology, Center for Experimental Molecular Medicine, Academic Medical Center, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1038/icb.2008.17DOI Listing
October 2008

Apoptosis is not the major death mechanism induced by celecoxib on rheumatoid arthritis synovial fibroblasts.

Arthritis Res Ther 2007 ;9(6):R128

Institut de Génétique Moléculaire de Montpellier, 1919 route de Mende, CNRS UMR5535, Montpellier, France.

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http://arthritis-research.biomedcentral.com/articles/10.1186
Publisher Site
http://dx.doi.org/10.1186/ar2342DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2246250PMC
March 2008

Specific TLR ligands regulate APRIL secretion by dendritic cells in a PKR-dependent manner.

Eur J Immunol 2007 Oct;37(10):2900-11

Laboratory of Experimental Oncology and Radiobiology, Academic Medical Center, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1002/eji.200737210DOI Listing
October 2007

Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) induces rheumatoid arthritis synovial fibroblast proliferation through mitogen-activated protein kinases and phosphatidylinositol 3-kinase/Akt.

J Biol Chem 2005 Apr 31;280(16):15709-18. Epub 2005 Jan 31.

INSERM Unit 454, Centre Hospitalier Universitaire Arnaud de Villeneuve, Centre Hospitalier Universitaire Lapeyronie, 34295 Montpellier, France.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M414469200
Publisher Site
http://dx.doi.org/10.1074/jbc.M414469200DOI Listing
April 2005

Potential role of APRIL as autocrine growth factor for megakaryocytopoiesis.

Blood 2004 Nov 22;104(10):3169-72. Epub 2004 Apr 22.

Laboratory of Hematology and Oncology, Istituto Superiore di Sanità, Rome, Italy.

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http://dx.doi.org/10.1182/blood-2003-11-3861DOI Listing
November 2004

APRIL promotes B-1 cell-associated neoplasm.

Cancer Cell 2004 Oct;6(4):399-408

Department of Immunology and Oncology, Centro Nacional de Biotecnología/CSIC, UAM Campus Cantoblanco, E-28049 Madrid, Spain.

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http://dx.doi.org/10.1016/j.ccr.2004.08.033DOI Listing
October 2004

Impaired clearance of virus-infected hepatocytes in transgenic mice expressing the hepatitis C virus polyprotein.

Gastroenterology 2004 Mar;126(3):859-72

Institut de Génétique Moléculaire, Centre National Recherche Scientifique, Unite Mixte de Recherche 5535, IFR 122, Montpelier, France.

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http://dx.doi.org/10.1053/j.gastro.2003.12.005DOI Listing
March 2004

TWE-PRIL; a fusion protein of TWEAK and APRIL.

Biochem Pharmacol 2003 Oct;66(8):1427-32

Department of Clinical Oncology, Leiden University Medical Center, Albinusdreef 2a, 2333 ZA Leiden, The Netherlands.

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http://dx.doi.org/10.1016/s0006-2952(03)00493-3DOI Listing
October 2003

Hepatocytes transgenic for the full hepatitis C virus open reading frame are resistant to fas-induced cell death.

Ann N Y Acad Sci 2002 Nov;973:214-7

Institut de Génétique Moléculaire, CNRS UMR 5535, F-34293 Montpellier Cedex 5, France.

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http://dx.doi.org/10.1111/j.1749-6632.2002.tb04635.xDOI Listing
November 2002

APRIL modulates B and T cell immunity.

J Clin Invest 2002 Jun;109(12):1587-98

Department of Immunology and Oncology, Centro Nacional de Biotecnología, Madrid, Spain.

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http://dx.doi.org/10.1172/JCI15034DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC151011PMC
June 2002