Publications by authors named "Michael H Gelb"

100Publications

Tandem Mass Spectrometry Enzyme Assays for Multiplex Detection of 10-Mucopolysaccharidoses in Dried Blood Spots and Fibroblasts.

Anal Chem 2020 09 13;92(17):11721-11727. Epub 2020 Aug 13.

Department of Chemistry, University of Washington, Seattle, Washington 98195, United States.

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http://dx.doi.org/10.1021/acs.analchem.0c01750DOI Listing
September 2020

A Case of Lysosomal Acid Lipase Deficiency Confirmed by Response to Sebelipase Alfa Therapy.

J Pediatr Gastroenterol Nutr 2020 Dec;71(6):726-730

Department of Pathology, University of California San Francisco, San Francisco, CA.

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http://dx.doi.org/10.1097/MPG.0000000000002870DOI Listing
December 2020

Detection of GM1-gangliosidosis in newborn dried blood spots by enzyme activity and biomarker assays using tandem mass spectrometry.

J Inherit Metab Dis 2020 Jun 7. Epub 2020 Jun 7.

Departments of Chemistry, University of Washington, Seattle, Washington, USA.

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http://dx.doi.org/10.1002/jimd.12269DOI Listing
June 2020

Macrophages Expressing GALC Improve Peripheral Krabbe Disease by a Mechanism Independent of Cross-Correction.

Neuron 2020 07 5;107(1):65-81.e9. Epub 2020 May 5.

Hunter James Kelly Research Institute, Departments of Biochemistry and Neurology, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo, NY 14203, USA. Electronic address:

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http://dx.doi.org/10.1016/j.neuron.2020.03.031DOI Listing
July 2020

Secreted Phospholipase A Group X Acts as an Adjuvant for Type 2 Inflammation, Leading to an Allergen-Specific Immune Response in the Lung.

J Immunol 2020 Jun 27;204(12):3097-3107. Epub 2020 Apr 27.

Division of Pulmonary, Critical Care and Sleep, Department of Medicine, University of Washington, Seattle, WA 98109;

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http://dx.doi.org/10.4049/jimmunol.2000102DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7375513PMC
June 2020

A highly multiplexed biochemical assay for analytes in dried blood spots: application to newborn screening and diagnosis of lysosomal storage disorders and other inborn errors of metabolism.

Genet Med 2020 Jul 20;22(7):1262-1268. Epub 2020 Apr 20.

Department of Chemistry, University of Washington, Seattle, WA, USA.

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http://dx.doi.org/10.1038/s41436-020-0790-9DOI Listing
July 2020

The Importance of Assay Imprecision near the Screen Cutoff for Newborn Screening of Lysosomal Storage Diseases.

Int J Neonatal Screen 2019 Jun 27;5(2). Epub 2019 Mar 27.

Department of Chemistry, University of Washington, Seattle, WA 98195, USA.

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http://dx.doi.org/10.3390/ijns5020017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6641561PMC
June 2019

Tandem mass spectrometry-based multiplex assays for α-mannosidosis and fucosidosis.

Mol Genet Metab 2019 07 10;127(3):207-211. Epub 2019 Jun 10.

Department of Chemistry, University of Washington, Seattle, WA 98195, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ymgme.2019.05.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6710107PMC
July 2019

Bioactivity of Farnesyltransferase Inhibitors Against and .

Front Cell Infect Microbiol 2019 29;9:180. Epub 2019 May 29.

Center for Discovery and Innovation in Parasitic Diseases, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California, San Diego, La Jolla, CA, United States.

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http://dx.doi.org/10.3389/fcimb.2019.00180DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6548881PMC
January 2020

Respective contribution of cytosolic phospholipase A2α and secreted phospholipase A IIA to inflammation and eicosanoid production in arthritis.

Prostaglandins Other Lipid Mediat 2019 08 23;143:106340. Epub 2019 May 23.

Centre de Recherche du Centre Hospitalier Universitaire de Québec, Faculté de Médecine de l'Université Laval, Département de microbiologie et immunologie, Québec, QC, G1V 4G2, Canada; Canadian National Transplantation Research Program, Edmonton, Alberta, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.prostaglandins.2019.106340DOI Listing
August 2019

Newborn Screening for Lysosomal Storage Disorders: Methodologies for Measurement of Enzymatic Activities in Dried Blood Spots.

Int J Neonatal Screen 2019 Mar 21;5(1). Epub 2018 Dec 21.

Head Reference Laboratory for Neonatal Screening, Center for Health Protection, National Institute for Public Health and the Environment (RIVM), P. O. Box 1, 3720 BA Bilthoven, The Netherlands.

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http://dx.doi.org/10.3390/ijns5010001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6448570PMC
March 2019

Newborn Screening for Lysosomal Storage Diseases: Methodologies, Screen Positive Rates, Normalization of Datasets, Second-Tier Tests, and Post-Analysis Tools.

Authors:
Michael H Gelb

Int J Neonatal Screen 2018 Sep 9;4(3). Epub 2018 Jul 9.

Departments of Chemistry, University of Washington, Seattle, WA 98195, USA;

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http://www.mdpi.com/2409-515X/4/3/23
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http://dx.doi.org/10.3390/ijns4030023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6419971PMC
September 2018

Function of secreted phospholipase A group-X in asthma and allergic disease.

Biochim Biophys Acta Mol Cell Biol Lipids 2019 06 5;1864(6):827-837. Epub 2018 Dec 5.

Department of Medicine, Division of Pulmonary, Critical Care and Sleep, University of Washington, Seattle, WA, United States of America. Electronic address:

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http://dx.doi.org/10.1016/j.bbalip.2018.11.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6431270PMC
June 2019

Detection of Infantile Batten Disease by Tandem Mass Spectrometry Assay of PPT1 Enzyme Activity in Dried Blood Spots.

Anal Chem 2018 10 24;90(20):12168-12171. Epub 2018 Sep 24.

Department of Chemistry , University of Washington , Seattle , Washington 98195 , United States.

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http://dx.doi.org/10.1021/acs.analchem.8b03188DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423508PMC
October 2018

One-step synthesis of carbon-13-labeled globotriaosylsphingosine (lyso-Gb3), an internal standard for biomarker analysis of Fabry disease.

Mol Genet Metab 2018 11 10;125(3):292-294. Epub 2018 Aug 10.

Departments of Chemistry, University of Washington, Seattle, WA 98195, USA; Departments of Biochemistry, University of Washington, Seattle, WA 98195, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S10967192183041
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http://dx.doi.org/10.1016/j.ymgme.2018.08.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6239936PMC
November 2018

Absolute Amounts of Analytes: When Gravimetric Methods Are Insufficient.

Authors:
Michael H Gelb

Clin Chem 2018 10 27;64(10):1430-1432. Epub 2018 Jul 27.

Departments of Chemistry and Biochemistry, University of Washington, Seattle, WA.

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http://dx.doi.org/10.1373/clinchem.2018.290486DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6447392PMC
October 2018

Detection of mucopolysaccharidosis III-A (Sanfilippo Syndrome-A) in dried blood spots (DBS) by tandem mass spectrometry.

Mol Genet Metab 2018 09 23;125(1-2):59-63. Epub 2018 May 23.

Department of Chemistry, Bagley Hall, University of Washington, Box 351700, Seattle, Washington 98195-1700, United States; Department of Biochemistry, University of Washington, Box 357350, Seattle, WA 98195-7350, United States. Electronic address:

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http://dx.doi.org/10.1016/j.ymgme.2018.05.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6175634PMC
September 2018

Multiplex tandem mass spectrometry assay for newborn screening of X-linked adrenoleukodystrophy, biotinidase deficiency, and galactosemia with flexibility to assay other enzyme assays and biomarkers.

Mol Genet Metab 2018 06 29;124(2):101-108. Epub 2018 Mar 29.

Departments of Chemistry, University of Washington, Seattle, WA 98195, USA; Departments of Biochemistry, University of Washington, Seattle, WA 98195, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ymgme.2018.03.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5976550PMC
June 2018

An Inexpensive, In-House-Made, Microdialysis Device for Measuring Drug-Protein Binding.

ACS Med Chem Lett 2018 Mar 28;9(3):279-282. Epub 2017 Sep 28.

Department of Chemistry, University of Washington, Seattle, Washington 98195, United States.

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http://dx.doi.org/10.1021/acsmedchemlett.7b00316DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5846030PMC
March 2018

Consensus guidelines for newborn screening, diagnosis and treatment of infantile Krabbe disease.

Orphanet J Rare Dis 2018 02 1;13(1):30. Epub 2018 Feb 1.

Wadsworth Center, New York State Department of Health, Newborn Screening Program, David Axelrod Institute, 120 New Scotland Ave., Albany, NY, 12201, USA.

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http://dx.doi.org/10.1186/s13023-018-0766-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5796396PMC
February 2018

Specific Substrate for the Assay of Lysosomal Acid Lipase.

Clin Chem 2018 04 16;64(4):690-696. Epub 2018 Jan 16.

Department of Chemistry, University of Washington, Seattle, WA;

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http://dx.doi.org/10.1373/clinchem.2017.282251DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6383652PMC
April 2018

1-Benzyl-3-aryl-2-thiohydantoin Derivatives as New Anti- Agents: SAR and in Vivo Efficacy.

ACS Med Chem Lett 2017 Aug 10;8(8):886-891. Epub 2017 Jul 10.

Department of Chemistry, University of Washington, Seattle, Washington 98195, United States.

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http://pubs.acs.org/doi/10.1021/acsmedchemlett.7b00230
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http://dx.doi.org/10.1021/acsmedchemlett.7b00230DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5554913PMC
August 2017

New Class of Antitrypanosomal Agents Based on Imidazopyridines.

ACS Med Chem Lett 2017 Jul 27;8(7):766-770. Epub 2017 Jun 27.

Departments of Chemistry, Medicine, and Biochemistry, University of Washington, Seattle, Washington 98195, United States.

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http://dx.doi.org/10.1021/acsmedchemlett.7b00202DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5512129PMC
July 2017

Newborn Screening for Lysosomal Storage Diseases: A Concise Review of the Literature on Screening Methods, Therapeutic Possibilities and Regional Programs.

Int J Neonatal Screen 2017 Jun 29;3(2). Epub 2017 Mar 29.

Departments of Chemistry and Biochemistry, University of Washington, Seattle, WD 98195, USA.

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http://dx.doi.org/10.3390/ijns3020006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5515486PMC
June 2017

Regulation of calcium release from the endoplasmic reticulum by the serine hydrolase ABHD2.

Biochem Biophys Res Commun 2017 09 3;490(4):1226-1231. Epub 2017 Jul 3.

Department of Pediatrics, National Jewish Health, Denver, CO, 80206, USA. Electronic address:

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http://dx.doi.org/10.1016/j.bbrc.2017.06.195DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5658124PMC
September 2017

Comparison of tandem mass spectrometry to fluorimetry for newborn screening of LSDs.

Mol Genet Metab Rep 2017 Sep 12;12:80-81. Epub 2017 Jun 12.

The Chinese Foundation of Health, Taipei, Taiwan.

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http://dx.doi.org/10.1016/j.ymgmr.2017.05.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5472143PMC
September 2017

Preface.

Authors:
Michael H Gelb

Methods Enzymol 2017 ;584:xv-xix

University of Washington, Seattle, WA, United States.

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https://linkinghub.elsevier.com/retrieve/pii/S00766879163046
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http://dx.doi.org/10.1016/S0076-6879(16)30469-4DOI Listing
October 2018

Preface.

Authors:
Michael H Gelb

Methods Enzymol 2017 ;583:xv-xix

University of Washington, Seattle, WA, United States.

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http://dx.doi.org/10.1016/S0076-6879(16)30456-6DOI Listing
October 2018

Urea Derivatives of 2-Aryl-benzothiazol-5-amines: A New Class of Potential Drugs for Human African Trypanosomiasis.

J Med Chem 2017 02 19;60(3):957-971. Epub 2016 Dec 19.

Department of Pathology and Laboratory Medicine, University of North Carolina , Chapel Hill, North Carolina 27599, United States.

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http://dx.doi.org/10.1021/acs.jmedchem.6b01163DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5362113PMC
February 2017

Newborn Screening for Lysosomal Storage Disorders: Quo Vadis?

Clin Chem 2016 11 14;62(11):1430-1438. Epub 2016 Sep 14.

Head of the Division of Metabolic Diseases, Academic Medical Centre, Emma Children's Hospital, University of Amsterdam, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1373/clinchem.2016.258459DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5545176PMC
November 2016

Newborn screening for Krabbe's disease.

J Neurosci Res 2016 11;94(11):1063-75

Laboratory of Human Genetics, Wadsworth Center, New York State Department of Health, Albany, New York.

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http://dx.doi.org/10.1002/jnr.23781DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5328187PMC
November 2016

Off-target effect of the cPLA2α inhibitor pyrrophenone: Inhibition of calcium release from the endoplasmic reticulum.

Biochem Biophys Res Commun 2016 10 9;479(1):61-6. Epub 2016 Sep 9.

Department of Pediatrics, National Jewish Health, 1400 Jackson St., Denver, CO 80206, USA. Electronic address:

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5063313PMC
http://dx.doi.org/10.1016/j.bbrc.2016.09.033DOI Listing
October 2016

Expression and Function of Group IIE Phospholipase A2 in Mouse Skin.

J Biol Chem 2016 07 23;291(30):15602-13. Epub 2016 May 23.

From the Lipid Metabolism Project and AMED-CREST, Japan Agency for Medical Research and Development, Tokyo 100-0004, Japan

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http://dx.doi.org/10.1074/jbc.M116.734657DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4957045PMC
July 2016

Dual Roles of Group IID Phospholipase A2 in Inflammation and Cancer.

J Biol Chem 2016 07 21;291(30):15588-601. Epub 2016 May 21.

From the Lipid Metabolism Project and AMED-CREST, Japan Agency for Medical Research and Development, Tokyo 100-0004, Japan

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http://dx.doi.org/10.1074/jbc.M116.734624DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4957044PMC
July 2016

Repurposing strategies for tropical disease drug discovery.

Bioorg Med Chem Lett 2016 06 30;26(11):2569-76. Epub 2016 Mar 30.

Northeastern University, Department of Chemistry & Chemical Biology, 360 Huntington Avenue, Boston, MA 02115, USA. Electronic address:

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http://dx.doi.org/10.1016/j.bmcl.2016.03.103DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4853260PMC
June 2016

Development of a potent 2-oxoamide inhibitor of secreted phospholipase A2 guided by molecular docking calculations and molecular dynamics simulations.

Bioorg Med Chem 2016 Apr 2;24(8):1683-95. Epub 2016 Mar 2.

Laboratory of Organic Chemistry, Department of Chemistry, National and Kapodistrian University of Athens, Panepistimiopolis, Athens 15771, Greece. Electronic address:

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http://dx.doi.org/10.1016/j.bmc.2016.02.040DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5292099PMC
April 2016

The role of group IIF-secreted phospholipase A2 in epidermal homeostasis and hyperplasia.

J Exp Med 2015 Oct 5;212(11):1901-19. Epub 2015 Oct 5.

Lipid Metabolism Project, Tokyo Metropolitan Institute of Medical Science, Tokyo 156-8506, Japan CREST, Japan Agency for Medical Research and Development (AMED) and Japan Science and Technology Agency (JST), Tokyo 100-0004, Japan

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http://dx.doi.org/10.1084/jem.20141904DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4612087PMC
October 2015

Fluorimetric assays for N-acetylgalactosamine-6-sulfatase and arylsulfatase B based on the natural substrates for confirmation of mucopolysaccharidoses types IVA and VI.

Clin Chim Acta 2015 Dec 15;451(Pt B):125-8. Epub 2015 Aug 15.

Department of Chemistry, University of Washington, Seattle, WA 98195, USA; Department of Biochemistry, University of Washington, Seattle, WA 98195, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cca.2015.08.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4656091PMC
December 2015

Endogenous secreted phospholipase A2 group X regulates cysteinyl leukotrienes synthesis by human eosinophils.

J Allergy Clin Immunol 2016 Jan 30;137(1):268-277.e8. Epub 2015 Jun 30.

Department of Chemistry, University of Washington, Seattle, Wash; Department of Biochemistry, University of Washington, Seattle, Wash.

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http://dx.doi.org/10.1016/j.jaci.2015.05.026DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4695325PMC
January 2016

Study of the role of cytosolic phospholipase A2 alpha in eicosanoid generation and thymocyte maturation in the thymus.

PLoS One 2015 13;10(5):e0126204. Epub 2015 May 13.

Centre de Recherche en Rhumatologie et Immunologie, Centre de Recherche du Centre Hospitalier Universitaire de Québec, Faculté de Médecine de l'Université Laval, Québec, QC, Canada.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0126204PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4430275PMC
February 2016

Matrix metalloproteinase-2 negatively regulates cardiac secreted phospholipase A2 to modulate inflammation and fever.

J Am Heart Assoc 2015 Mar 27;4(4). Epub 2015 Mar 27.

Department of Biochemistry, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, Canada (E.B., S.H.A., X.W., C.F.P.) Cardiovascular Research Group, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, Canada (Z.K., C.F.P.) Mazankowski Alberta Heart Institute, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, Canada (Z.K., C.F.P.).

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http://dx.doi.org/10.1161/JAHA.115.001868DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4579961PMC
March 2015

Computational protein design enables a novel one-carbon assimilation pathway.

Proc Natl Acad Sci U S A 2015 Mar 9;112(12):3704-9. Epub 2015 Mar 9.

Department of Biochemistry and the Institute for Protein Design, Biomolecular Structure and Design Program, Howard Hughes Medical Institute,

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http://dx.doi.org/10.1073/pnas.1500545112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4378393PMC
March 2015

Newborn screening for lysosomal storage diseases.

Clin Chem 2015 Feb 4;61(2):335-46. Epub 2014 Dec 4.

Department of Chemistry.

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http://dx.doi.org/10.1373/clinchem.2014.225771DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4345406PMC
February 2015

Recent developments in drug discovery for leishmaniasis and human African trypanosomiasis.

Chem Rev 2014 Nov 3;114(22):11305-47. Epub 2014 Nov 3.

Genomics Institute of the Novartis Research Foundation , 10675 John Jay Hopkins Drive, San Diego, California 92121, United States.

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http://dx.doi.org/10.1021/cr500365fDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4633805PMC
November 2014

WITHDRAWN: Newborn screening for lysosomal disordersby tandem mass spectrometry.

Authors:
Michael H Gelb

Clin Biochem 2014 Jun 6. Epub 2014 Jun 6.

Department of Chemistry, University of Washington, Seattle, WA 98195, USA; Department of Biochemistry, University of Washington, Seattle, WA 98195, USA.

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http://dx.doi.org/10.1016/j.clinbiochem.2014.05.015DOI Listing
June 2014

The adipocyte-inducible secreted phospholipases PLA2G5 and PLA2G2E play distinct roles in obesity.

Cell Metab 2014 Jul 5;20(1):119-32. Epub 2014 Jun 5.

Lipid Metabolism Project, Tokyo Metropolitan Institute of Medical Science, 2-1-6 Kamikitazawa, Setagaya-ku, Tokyo 156-8506, Japan; CREST, Japan Science and Technology Agency, 4-1-8 Honcho, Kawaguchi, Saitama 332-0012, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.cmet.2014.05.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4079757PMC
July 2014

Improved reagents for newborn screening of mucopolysaccharidosis types I, II, and VI by tandem mass spectrometry.

Anal Chem 2014 May 21;86(9):4508-14. Epub 2014 Apr 21.

Departments of Chemistry, ‡Pediatrics, and §Biochemistry, University of Washington , Seattle, Washington 98195-1700, United States.

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http://dx.doi.org/10.1021/ac5004135DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4014144PMC
May 2014

Quantification of sulfatides in dried blood and urine spots from metachromatic leukodystrophy patients by liquid chromatography/electrospray tandem mass spectrometry.

Clin Chim Acta 2014 Jun 23;433:39-43. Epub 2013 Dec 23.

Departments of Chemistry, University of Washington, Seattle, WA 98195, United States; Departments of Biochemistry, University of Washington, Seattle, WA 98195, United States. Electronic address:

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http://dx.doi.org/10.1016/j.cca.2013.12.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4039571PMC
June 2014

LC/ESI-MS/MS detection of FAs by charge reversal derivatization with more than four orders of magnitude improvement in sensitivity.

J Lipid Res 2013 Dec 14;54(12):3523-30. Epub 2013 Aug 14.

Departments of Chemistry and University of Washington, Seattle, WA 98195.

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http://dx.doi.org/10.1194/jlr.D040782DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3826698PMC
December 2013

Key role of group v secreted phospholipase A2 in Th2 cytokine and dendritic cell-driven airway hyperresponsiveness and remodeling.

PLoS One 2013 25;8(2):e56172. Epub 2013 Feb 25.

Center for Allergy and Inflammation, UW Medicine at South Lake Union, Department of Medicine, University of Washington, Seattle, Washington, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0056172PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3581544PMC
September 2013

Epithelial regulation of eicosanoid production in asthma.

Pulm Pharmacol Ther 2012 Dec;25(6):432-7

Division of Pulmonary and Critical Care, University of Washington, Box 356522, 1959 NE Pacific Street, Seattle, WA 98195, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3627426PMC
http://dx.doi.org/10.1016/j.pupt.2012.02.004DOI Listing
December 2012

High-throughput assay of 9 lysosomal enzymes for newborn screening.

Clin Chem 2013 Mar 11;59(3):502-11. Epub 2013 Jan 11.

Department of Chemistry, University of Washington, Seattle, WA, USA.

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http://dx.doi.org/10.1373/clinchem.2012.189936DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4737435PMC
March 2013

Biochemical characterization of selective inhibitors of human group IIA secreted phospholipase A(2) and hyaluronic acid-linked inhibitor conjugates.

Biochemistry 2012 Oct 18;51(43):8617-26. Epub 2012 Oct 18.

Departments of Chemistry and Biomolecular Structure and Design, University of Washington, Seattle, WA 98195, USA.

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http://dx.doi.org/10.1021/bi301140bDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3549043PMC
October 2012

Endogenous sterol biosynthesis is important for mitochondrial function and cell morphology in procyclic forms of Trypanosoma brucei.

Int J Parasitol 2012 Oct 29;42(11):975-89. Epub 2012 Aug 29.

Instituto de Parasitología y Biomedicina López-Neyra, Consejo Superior de Investigaciones Científicas, Avda. del Conocimiento s/n, Armilla, Granada, Spain.

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http://linkinghub.elsevier.com/retrieve/pii/S002075191200197
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http://dx.doi.org/10.1016/j.ijpara.2012.07.012DOI Listing
October 2012

High-throughput assay of secreted phospholipases A₂ inhibitors.

Methods Mol Biol 2012 ;861:149-58

Departments of Chemistry and Biochemistry, University of Washington, Seattle, WA, USA.

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http://dx.doi.org/10.1007/978-1-61779-600-5_10DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4084959PMC
July 2012

Phospholipases: an overview.

Methods Mol Biol 2012 ;861:63-85

National School of Engineers of Sfax, University of Sfax, Sfax, Tunisia.

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http://dx.doi.org/10.1007/978-1-61779-600-5_4DOI Listing
July 2012