Michael Grusch

Michael Grusch

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Michael Grusch

Michael Grusch

Publications by authors named "Michael Grusch"

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Angioregulatory microRNAs in Colorectal Cancer.

Authors:
Mohammad Hasan Soheilifar Michael Grusch Hoda Keshmiri Neghab Razieh Amini Hamid Maadi Massoud Saidijam Zhixiang Wang

Cancers (Basel) 2019 Dec 26;12(1). Epub 2019 Dec 26.

Department of Medical Genetics, and Signal Transduction Research Group, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, AB T6G 2H7, Canada.

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http://dx.doi.org/10.3390/cancers12010071DOI Listing
December 2019

Modulation of cardiac optogenetics by vitamin A.

Authors:
Hoda Keshmiri Neghab Bahram Goliaei Ali A Saboury Gholamreza Esmaeeli Djavid Majid Pornour Jun Hong Michael Grusch

Biofactors 2019 Nov 11;45(6):983-990. Epub 2019 Sep 11.

Department of Medicine I, Comprehensive Cancer Center Vienna, Institute of Cancer Research, Medical University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.1002/biof.1564DOI Listing
November 2019

Gallic acid, a common dietary phenolic protects against high fat diet induced DNA damage.

Authors:
Tahereh Setayesh Armen Nersesyan Miroslav Mišík Rahil Noorizadeh Elisabeth Haslinger Tahereh Javaheri Elisabeth Lang Michael Grusch Wolfgang Huber Alexander Haslberger Siegfried Knasmüller

Eur J Nutr 2019 Sep 23;58(6):2315-2326. Epub 2018 Jul 23.

Institute of Cancer Research, Department of Medicine I, Medical University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.1007/s00394-018-1782-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6689278PMC
September 2019

Long-Term Vemurafenib Exposure Induced Alterations of Cell Phenotypes in Melanoma: Increased Cell Migration and Its Association with EGFR Expression.

Authors:
Eszter Molnár Tamás Garay Marco Donia Marcell Baranyi Dominika Rittler Walter Berger József Tímár Michael Grusch Balázs Hegedűs

Int J Mol Sci 2019 Sep 11;20(18). Epub 2019 Sep 11.

2nd Department of Pathology, Semmelweis University, H-1091 Budapest, Hungary.

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http://dx.doi.org/10.3390/ijms20184484DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6770060PMC
September 2019

Expression of FGFR1-4 in Malignant Pleural Mesothelioma Tissue and Corresponding Cell Lines and its Relationship to Patient Survival and FGFR Inhibitor Sensitivity.

Authors:
Gregor Vlacic Mir A Hoda Thomas Klikovits Katharina Sinn Elisabeth Gschwandtner Katja Mohorcic Karin Schelch Christine Pirker Barbara Peter-Vörösmarty Jelena Brankovic Balazs Dome Viktoria Laszlo Tanja Cufer Ales Rozman Walter Klepetko Bettina Grasl-Kraupp Balazs Hegedus Walter Berger Izidor Kern Michael Grusch

Cells 2019 09 16;8(9). Epub 2019 Sep 16.

Institute of Cancer Research, Department of Medicine I, Medical University of Vienna, 1090 Vienna, Austria.

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http://dx.doi.org/10.3390/cells8091091DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6769772PMC
September 2019

Correction: Fibroblast growth factor receptor 4 induced resistance to radiation therapy in colorectal cancer.

Authors:
Mohamed A Ahmed Edgar Selzer Wolfgang Dörr Gerd Jomrich Felix Harpain Gerd R Silberhumer Leonhard Müllauer Klaus Holzmann Bettina Grasl-Kraupp Michael Grusch Walter Berger Brigitte Marian

Oncotarget 2019 Sep 3;10(51):5385-5386. Epub 2019 Sep 3.

Institute of Cancer Research, Department of Medicine I, Medical University of Vienna, Austria.

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http://dx.doi.org/10.18632/oncotarget.27186DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6731104PMC
September 2019

The FAK inhibitor BI 853520 inhibits spheroid formation and orthotopic tumor growth in malignant pleural mesothelioma.

Authors:
Viktoria Laszlo Zsuzsanna Valko Judit Ozsvar Ildiko Kovacs Tamas Garay Mir Alireza Hoda Thomas Klikovits Paul Stockhammer Clemens Aigner Marion Gröger Walter Klepetko Walter Berger Michael Grusch Jozsef Tovari Irene C Waizenegger Balazs Dome Balazs Hegedus

J Mol Med (Berl) 2019 02 11;97(2):231-242. Epub 2018 Dec 11.

Division of Thoracic Surgery, Department of Surgery, Comprehensive Cancer Center, Medical University of Vienna, Waehringer Guertel 18-20, A-1090, Vienna, Austria.

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http://link.springer.com/10.1007/s00109-018-1725-7
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http://dx.doi.org/10.1007/s00109-018-1725-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6348072PMC
February 2019

FGF8 induces therapy resistance in neoadjuvantly radiated rectal cancer.

Authors:
Felix Harpain Mohamed A Ahmed Xenia Hudec Gerald Timelthaler Gerd Jomrich Leonhard Müllauer Edgar Selzer Wolfgang Dörr Michael Bergmann Klaus Holzmann Bettina Grasl-Kraupp Michael Grusch Walter Berger Brigitte Marian Gerd R Silberhumer

J Cancer Res Clin Oncol 2019 Jan 1;145(1):77-86. Epub 2018 Oct 1.

Department of Surgery, Medical University Vienna, Vienna, Austria.

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http://dx.doi.org/10.1007/s00432-018-2757-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6326005PMC
January 2019

Lysosomal Sequestration Impairs the Activity of the Preclinical FGFR Inhibitor PD173074.

Authors:
Bernhard Englinger Sebastian Kallus Julia Senkiv Anna Laemmerer Patrick Moser Lisa Gabler Diana Groza Christian R Kowol Petra Heffeter Michael Grusch Walter Berger

Cells 2018 Dec 8;7(12). Epub 2018 Dec 8.

Institute of Cancer Research and Comprehensive Cancer Center, Department of Medicine I, Medical University of Vienna, A-1090 Vienna, Austria.

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http://www.mdpi.com/2073-4409/7/12/259
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http://dx.doi.org/10.3390/cells7120259DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6315953PMC
December 2018

Epigenetic Biomarkers in Cancer.

Authors:
Yuen Yee Cheng Hong Chuan Jin Michael W Y Chan Wai Kit Chu Michael Grusch

Dis Markers 2018;2018:4987103. Epub 2018 Feb 20.

Institute of Cancer Research, Medical University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.1155/2018/4987103DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5838454PMC
October 2018

The thiosemicarbazone MeNNMe induces paraptosis by disrupting the ER thiol redox homeostasis based on protein disulfide isomerase inhibition.

Authors:
Sonja Hager Katharina Korbula Björn Bielec Michael Grusch Christine Pirker Markus Schosserer Lisa Liendl Magdalena Lang Johannes Grillari Karin Nowikovsky Veronika F S Pape Thomas Mohr Gergely Szakács Bernhard K Keppler Walter Berger Christian R Kowol Petra Heffeter

Cell Death Dis 2018 10 15;9(11):1052. Epub 2018 Oct 15.

Institute of Cancer Research and Comprehensive Cancer Center, Department of Medicine I, Medical University of Vienna, Borschkegasse 8a, A-1090, Vienna, Austria.

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http://www.nature.com/articles/s41419-018-1102-z
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http://dx.doi.org/10.1038/s41419-018-1102-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6189190PMC
October 2018

Nintedanib Is Active in Malignant Pleural Mesothelioma Cell Models and Inhibits Angiogenesis and Tumor Growth .

Authors:
Viktoria Laszlo Zsuzsanna Valko Ildiko Kovacs Judit Ozsvar Mir Alireza Hoda Thomas Klikovits Dora Lakatos Andras Czirok Tamas Garay Alexander Stiglbauer Thomas H Helbich Marion Gröger Jozsef Tovari Walter Klepetko Christine Pirker Michael Grusch Walter Berger Frank Hilberg Balazs Hegedus Balazs Dome

Clin Cancer Res 2018 08 3;24(15):3729-3740. Epub 2018 May 3.

Division of Thoracic Surgery, Department of Surgery, Comprehensive Cancer Centre Vienna, Medical University Vienna, Austria.

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http://clincancerres.aacrjournals.org/lookup/doi/10.1158/107
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http://dx.doi.org/10.1158/1078-0432.CCR-17-1507DOI Listing
August 2018

DNA Methylation as a Noninvasive Epigenetic Biomarker for the Detection of Cancer.

Authors:
Catherine Leygo Marissa Williams Hong Chuan Jin Michael W Y Chan Wai Kit Chu Michael Grusch Yuen Yee Cheng

Dis Markers 2017 5;2017:3726595. Epub 2017 Sep 5.

Asbestos Disease Research Institute, Sydney Medical School, University of Sydney, Rhodes, NSW, Australia.

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http://dx.doi.org/10.1155/2017/3726595DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5605861PMC
June 2018

Pan-RAF and MEK vertical inhibition enhances therapeutic response in non-V600 BRAF mutant cells.

Authors:
Eszter Molnár Dominika Rittler Marcell Baranyi Michael Grusch Walter Berger Balázs Döme József Tóvári Clemens Aigner József Tímár Tamás Garay Balázs Hegedűs

BMC Cancer 2018 May 8;18(1):542. Epub 2018 May 8.

2nd Department of Pathology, Semmelweis University, Budapest, 1091, Hungary.

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http://dx.doi.org/10.1186/s12885-018-4455-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5941622PMC
May 2018

FGF2 and EGF induce epithelial-mesenchymal transition in malignant pleural mesothelioma cells via a MAPKinase/MMP1 signal.

Authors:
Karin Schelch Christina Wagner Sonja Hager Christine Pirker Katharina Siess Elisabeth Lang Ruby Lin Michaela B Kirschner Thomas Mohr Luka Brcic Brigitte Marian Klaus Holzmann Bettina Grasl-Kraupp Georg Krupitza Viktoria Laszlo Thomas Klikovits Balazs Dome Balazs Hegedus Tamas Garay Glen Reid Nico van Zandwijk Walter Klepetko Walter Berger Michael Grusch Mir Alireza Hoda

Carcinogenesis 2018 04;39(4):534-545

Translational Thoracic Oncology Laboratory, Division of Thoracic Surgery, Department of Surgery, Comprehensive Cancer Center Vienna.

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http://dx.doi.org/10.1093/carcin/bgy018DOI Listing
April 2018

Bacterial ghosts as adjuvant to oxaliplatin chemotherapy in colorectal carcinomatosis.

Authors:
Diana Groza Sebastian Gehrig Pavol Kudela Martin Holcmann Christine Pirker Carina Dinhof Hemma H Schueffl Marek Sramko Julia Hoebart Fatih Alioglu Michael Grusch Manfred Ogris Werner Lubitz Bernhard K Keppler Irena Pashkunova-Martic Christian R Kowol Maria Sibilia Walter Berger Petra Heffeter

Oncoimmunology 2018 16;7(5):e1424676. Epub 2018 Feb 16.

Institute of Cancer Research, Department of Medicine I, Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.1080/2162402X.2018.1424676DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5927527PMC
February 2018

A link between the fibroblast growth factor axis and the miR-16 family reveals potential new treatment combinations in mesothelioma.

Authors:
Karin Schelch Michaela B Kirschner Marissa Williams Yuen Y Cheng Nico van Zandwijk Michael Grusch Glen Reid

Mol Oncol 2018 01 18;12(1):58-73. Epub 2017 Nov 18.

Asbestos Diseases Research Institute, Sydney, Australia.

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http://dx.doi.org/10.1002/1878-0261.12150DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5748487PMC
January 2018

Circulating complement component 4d (C4d) correlates with tumor volume, chemotherapeutic response and survival in patients with malignant pleural mesothelioma.

Authors:
Thomas Klikovits Paul Stockhammer Viktoria Laszlo Yawen Dong Mir Alireza Hoda Bahil Ghanim Isabelle Opitz Thomas Frauenfelder Thi Dan Linh Nguyen-Kim Walter Weder Walter Berger Michael Grusch Clemens Aigner Walter Klepetko Balazs Dome Ferenc Renyi-Vamos Rudolf Oehler Balazs Hegedus

Sci Rep 2017 11 28;7(1):16456. Epub 2017 Nov 28.

Translational Thoracic Oncology Laboratory, Division of Thoracic Surgery, Department of Surgery, Comprehensive Cancer Center Vienna, Medical University of Vienna, Waehringer Guertel 18-20, 1090, Vienna, Austria.

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http://dx.doi.org/10.1038/s41598-017-16551-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5705645PMC
November 2017

FGF5 is expressed in melanoma and enhances malignancy and .

Authors:
Sara Ghassemi Katharina Vejdovszky Emine Sahin Lukas Ratzinger Karin Schelch Thomas Mohr Barbara Peter-Vörösmarty Jelena Brankovic Andreas Lackner Alexandra Leopoldi Diana Meindl Christine Pirker Balazs Hegedus Brigitte Marian Klaus Holzmann Bettina Grasl-Kraupp Petra Heffeter Walter Berger Michael Grusch

Oncotarget 2017 Oct 23;8(50):87750-87762. Epub 2017 Sep 23.

Institute of Cancer Research, Department of Medicine I, Comprehensive Cancer Center Vienna, Medical University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.18632/oncotarget.21184DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5675669PMC
October 2017

Intrinsic fluorescence of the clinically approved multikinase inhibitor nintedanib reveals lysosomal sequestration as resistance mechanism in FGFR-driven lung cancer.

Authors:
Bernhard Englinger Sebastian Kallus Julia Senkiv Daniela Heilos Lisa Gabler Sushilla van Schoonhoven Alessio Terenzi Patrick Moser Christine Pirker Gerald Timelthaler Walter Jäger Christian R Kowol Petra Heffeter Michael Grusch Walter Berger

J Exp Clin Cancer Res 2017 09 7;36(1):122. Epub 2017 Sep 7.

Institute of Cancer Research and Comprehensive Cancer Center, Department of Medicine I, Medical University of Vienna, Borschkegasse 8a, A-1090, Vienna, Austria.

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http://dx.doi.org/10.1186/s13046-017-0592-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5590147PMC
September 2017

The plasma membrane Ca pump PMCA4b inhibits the migratory and metastatic activity of BRAF mutant melanoma cells.

Authors:
Luca Hegedũs Tamás Garay Eszter Molnár Karolina Varga Ágnes Bilecz Szilvia Török Rita Padányi Katalin Pászty Matthias Wolf Michael Grusch Enikõ Kállay Balázs Döme Walter Berger Balázs Hegedũs Agnes Enyedi

Int J Cancer 2017 06 17;140(12):2758-2770. Epub 2016 Nov 17.

2nd Department of Pathology, Semmelweis University, Budapest, Hungary.

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http://dx.doi.org/10.1002/ijc.30503DOI Listing
June 2017

Irinotecan Upregulates Fibroblast Growth Factor Receptor 3 Expression in Colorectal Cancer Cells, Which Mitigates Irinotecan-Induced Apoptosis.

Authors:
Zeynep N Erdem Stefanie Schwarz Daniel Drev Christine Heinzle Andrea Reti Petra Heffeter Xenia Hudec Klaus Holzmann Bettina Grasl-Kraupp Walter Berger Michael Grusch Brigitte Marian

Transl Oncol 2017 Jun 22;10(3):332-339. Epub 2017 Mar 22.

Medical University of Vienna, Department of Medicine 1, Institute of Cancer Research and Comprehensive Cancer Center Vienna, Borschkegasse 8a, 1090 Vienna, Austria. Electronic address:

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http://dx.doi.org/10.1016/j.tranon.2017.02.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5367848PMC
June 2017

Histone Deacetylase Inhibitor Treatment Increases the Expression of the Plasma Membrane Ca Pump PMCA4b and Inhibits the Migration of Melanoma Cells Independent of ERK.

Authors:
Luca Hegedüs Rita Padányi Judit Molnár Katalin Pászty Karolina Varga István Kenessey Eszter Sárközy Matthias Wolf Michael Grusch Zoltán Hegyi László Homolya Clemens Aigner Tamás Garay Balázs Hegedüs József Tímár Enikö Kállay Ágnes Enyedi

Front Oncol 2017 24;7:95. Epub 2017 May 24.

2nd Institute of Pathology, Semmelweis University, Budapest, Hungary.

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http://dx.doi.org/10.3389/fonc.2017.00095DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5442207PMC
May 2017

Trabectedin Is Active against Malignant Pleural Mesothelioma Cell and Xenograft Models and Synergizes with Chemotherapy and Bcl-2 Inhibition In Vitro.

Authors:
Mir A Hoda Christine Pirker Yawen Dong Karin Schelch Petra Heffeter Kushtrim Kryeziu Sushilla van Schoonhoven Thomas Klikovits Viktoria Laszlo Anita Rozsas Judit Ozsvar Walter Klepetko Balazs Döme Michael Grusch Balazs Hegedüs Walter Berger

Mol Cancer Ther 2016 10 10;15(10):2357-2369. Epub 2016 Aug 10.

Applied and Experimental Oncology, Institute of Cancer Research, Department of Medicine I, Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.1158/1535-7163.MCT-15-0846DOI Listing
October 2016

Fibroblast growth factor receptor 4 induced resistance to radiation therapy in colorectal cancer.

Authors:
Mohamed A Ahmed Edgar Selzer Wolfgang Dörr Gerd Jomrich Felix Harpain Gerd R Silberhumer Leonhard Müllauer Klaus Holzmann Bettina Grasl-Kraupp Michael Grusch Walter Berger Brigitte Marian

Oncotarget 2016 Oct;7(43):69976-69990

Institute of Cancer Research, Department of Medicine I, Medical University of Vienna, Austria.

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http://dx.doi.org/10.18632/oncotarget.12099DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342528PMC
October 2016

Circulating activin A is a novel prognostic biomarker in malignant pleural mesothelioma - A multi-institutional study.

Authors:
Mir Alireza Hoda Yawen Dong Anita Rozsas Thomas Klikovits Viktoria Laszlo Bahil Ghanim Paul Stockhammer Judit Ozsvar Marko Jakopovic Miroslav Samarzija Luka Brcic Matyas Bendek Ildiko Szirtes Glen Reid Michaela B Kirschner Steven C Kao Isabelle Opitz Walter Weder Thomas Frauenfelder Thi Dan Linh Nguyen-Kim Clemens Aigner Walter Klepetko Nico van Zandwijk Walter Berger Balazs Dome Michael Grusch Balazs Hegedus

Eur J Cancer 2016 08 8;63:64-73. Epub 2016 Jun 8.

Division of Thoracic Surgery, Department of Surgery, Comprehensive Cancer Center Vienna, Medical University of Vienna, Vienna, Austria; Department of Biomedical Imaging and Image-guided Therapy, Division of Molecular and Gender Imaging, Medical University of Vienna, Vienna, Austria; MTA-SE Molecular Oncology Research Group, Hungarian Academy of Sciences, Budapest, Hungary. Electronic address:

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http://dx.doi.org/10.1016/j.ejca.2016.04.018DOI Listing
August 2016

Acquired nintedanib resistance in FGFR1-driven small cell lung cancer: role of endothelin-A receptor-activated ABCB1 expression.

Authors:
Bernhard Englinger Daniela Lötsch Christine Pirker Thomas Mohr Sushilla van Schoonhoven Bernd Boidol Charles-Hugues Lardeau Melanie Spitzwieser Pál Szabó Petra Heffeter Irene Lang Margit Cichna-Markl Bettina Grasl-Kraupp Brigitte Marian Michael Grusch Stefan Kubicek Gergely Szakács Walter Berger

Oncotarget 2016 Aug;7(31):50161-50179

Institute of Cancer Research, Department of Medicine I, Medical University of Vienna, Austria.

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http://dx.doi.org/10.18632/oncotarget.10324DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5226575PMC
August 2016

The optogenetic promise for oncology: Episode I.

Authors:
Alvaro Ingles-Prieto Eva Reichhart Karin Schelch Harald Janovjak Michael Grusch

Mol Cell Oncol 2014 Oct-Dec;1(4):e964045. Epub 2014 Oct 29.

Institute of Cancer Research; Department of Medicine I; Comprehensive Cancer Center Vienna; Medical University of Vienna ; Vienna, Austria.

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http://dx.doi.org/10.4161/23723548.2014.964045DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905200PMC
June 2016

High circulating activin A level is associated with tumor progression and predicts poor prognosis in lung adenocarcinoma.

Authors:
Mir Alireza Hoda Anita Rozsas Elisabeth Lang Thomas Klikovits Zoltan Lohinai Szilvia Torok Judit Berta Matyas Bendek Walter Berger Balazs Hegedus Walter Klepetko Ferenc Renyi-Vamos Michael Grusch Balazs Dome Viktoria Laszlo

Oncotarget 2016 Mar;7(12):13388-99

Translational Thoracic Oncology Laboratory, Division of Thoracic Surgery, Department of Surgery, Comprehensive Cancer Center Vienna, Medical University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.18632/oncotarget.7796DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4924649PMC
March 2016

Fibroblast growth factor receptor 3 isoforms: Novel therapeutic targets for hepatocellular carcinoma?

Authors:
Jakob Paur Lisa Nika Christiane Maier Alexander Moscu-Gregor Julia Kostka Daniela Huber Thomas Mohr Petra Heffeter Waltraud C Schrottmaier Sonja Kappel Daniela Kandioler Klaus Holzmann Brigitte Marian Walter Berger Michael Grusch Bettina Grasl-Kraupp

Hepatology 2015 Dec 16;62(6):1767-78. Epub 2015 Oct 16.

Department of Medicine I, Division: Institute of Cancer Research, Comprehensive Cancer Center Vienna, Medical University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.1002/hep.28023DOI Listing
December 2015

Light-assisted small-molecule screening against protein kinases.

Authors:
Álvaro Inglés-Prieto Eva Reichhart Markus K Muellner Matthias Nowak Sebastian M B Nijman Michael Grusch Harald Janovjak

Nat Chem Biol 2015 Dec 12;11(12):952-4. Epub 2015 Oct 12.

Institute of Science and Technology Austria (IST Austria), Klosterneuburg, Austria.

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http://dx.doi.org/10.1038/nchembio.1933DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4652335PMC
December 2015

Epigenetic down-regulation of integrin α7 increases migratory potential and confers poor prognosis in malignant pleural mesothelioma.

Authors:
Viktoria Laszlo Mir Alireza Hoda Tamas Garay Christine Pirker Bahil Ghanim Thomas Klikovits Yawen W Dong Anita Rozsas Istvan Kenessey Ildiko Szirtes Michael Grusch Marko Jakopovic Miroslav Samarzija Luka Brcic Izidor Kern Ales Rozman Helmut Popper Sabine Zöchbauer-Müller Gerwin Heller Corinna Altenberger Barbara Ziegler Walter Klepetko Walter Berger Balazs Dome Balazs Hegedus

J Pathol 2015 Oct 14;237(2):203-14. Epub 2015 Jul 14.

Division of Thoracic Surgery, Department of Surgery, Comprehensive Cancer Center Vienna, Medical University of Vienna, Austria.

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http://dx.doi.org/10.1002/path.4567DOI Listing
October 2015

Is fibroblast growth factor receptor 4 a suitable target of cancer therapy?

Authors:
Christine Heinzle Zeynep Erdem Jakob Paur Bettina Grasl-Kraupp Klaus Holzmann Michael Grusch Walter Berger Brigitte Marian

Curr Pharm Des 2014 ;20(17):2881-98

Institute of Cancer Research, Department of Medicine 1, Medical University Vienna, Borschkegasse 8a, 1090 Vienna, Austria.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5453246PMC
http://dx.doi.org/10.2174/13816128113199990594DOI Listing
September 2015

Canine and human sarcomas exhibit predominant FGFR1 expression and impaired viability after inhibition of signaling.

Authors:
Nicole Schweiger Marlene Hauck Heinrich Steinhoff Sandra Sampl Martin Reifinger Ingrid Walter Theresa Kreilmeier Brigitte Marian Michael Grusch Walter Berger Klaus Holzmann Miriam Kleiter

Mol Carcinog 2015 Sep 9;54(9):841-52. Epub 2014 Apr 9.

Department for Companion Animals and Horses, University of Veterinary Medicine Vienna, Vienna, Austria.

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http://doi.wiley.com/10.1002/mc.22155
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http://dx.doi.org/10.1002/mc.22155DOI Listing
September 2015

Sensitivity of Melanoma Cells to EGFR and FGFR Activation but Not Inhibition is Influenced by Oncogenic BRAF and NRAS Mutations.

Authors:
Tamás Garay Eszter Molnár Éva Juhász Viktória László Tamás Barbai Judit Dobos Karin Schelch Christine Pirker Michael Grusch Walter Berger József Tímár Balázs Hegedűs

Pathol Oncol Res 2015 Sep 9;21(4):957-68. Epub 2015 Mar 9.

2nd Department of Pathology, Semmelweis University, Üllői út 93, H-1091, Budapest, Hungary.

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http://link.springer.com/content/pdf/10.1007/s12253-015-9916
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http://link.springer.com/10.1007/s12253-015-9916-9
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http://dx.doi.org/10.1007/s12253-015-9916-9DOI Listing
September 2015

Fibulin-3 levels in malignant pleural mesothelioma are associated with prognosis but not diagnosis.

Authors:
Michaela B Kirschner Emily Pulford Mir Alireza Hoda Anita Rozsas Kim Griggs Yuen Yee Cheng J James B Edelman Steven C Kao Rebecca Hyland Yawen Dong Viktoria László Thomas Klikovits Michael P Vallely Michael Grusch Balazs Hegedus Balazs Dome Walter Klepetko Nico van Zandwijk Sonja Klebe Glen Reid

Br J Cancer 2015 Sep 11;113(6):963-9. Epub 2015 Aug 11.

Asbestos Diseases Research Institute (ADRI), Sydney, NSW 2139, Australia.

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http://dx.doi.org/10.1038/bjc.2015.286DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4578085PMC
September 2015

The germacranolide sesquiterpene lactone neurolenin B of the medicinal plant Neurolaena lobata (L.) R.Br. ex Cass inhibits NPM/ALK-driven cell expansion and NF-κB-driven tumour intravasation.

Authors:
Christine Unger Izabella Kiss Andrea Vasas Ildikó Lajter Nina Kramer Atanas Georgiev Atanasov Chi Huu Nguyen Waranya Chatuphonprasert Stefan Brenner Sigurd Krieger Ruxandra McKinnon Andrea Peschel Renate Kain Philipp Saiko Thomas Szekeres Lukas Kenner Melanie R Hassler Rene Diaz Richard Frisch Verena M Dirsch Walter Jäger Rainer de Martin Valery N Bochkov Claus M Passreiter Barbara Peter-Vörösmarty Robert M Mader Michael Grusch Helmut Dolznig Brigitte Kopp Istvan Zupko Judit Hohmann Georg Krupitza

Phytomedicine 2015 Aug 26;22(9):862-74. Epub 2015 Jun 26.

Clinical Institute of Pathology, Medical University of Vienna, Waehringer Guertel 18-20, A-1090 Vienna, Austria.

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http://dx.doi.org/10.1016/j.phymed.2015.06.003DOI Listing
August 2015

A eudesmane-type sesquiterpene isolated from Pluchea odorata (L.) Cass. combats three hallmarks of cancer cells: Unrestricted proliferation, escape from apoptosis and early metastatic outgrowth in vitro.

Authors:
Michael Blaschke Ruxandra McKinnon Chi Huu Nguyen Silvio Holzner Martin Zehl Atanas Georgiev Atanasov Karin Schelch Sigurd Krieger Rene Diaz Richard Frisch Björn Feistel Walter Jäger Gerhard F Ecker Verena M Dirsch Michael Grusch Istvan Zupko Ernst Urban Brigitte Kopp Georg Krupitza

Mutat Res 2015 Jul 5;777:79-90. Epub 2015 May 5.

Department of Clinical Pathology, Medical University of Vienna, Waehringer Guertel 18-20, Austria. Electronic address:

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http://dx.doi.org/10.1016/j.mrfmmm.2015.04.011DOI Listing
July 2015

Fatty acid synthase is a metabolic marker of cell proliferation rather than malignancy in ovarian cancer and its precursor cells.

Authors:
Daniel Veigel Renate Wagner Gerald Stübiger Michael Wuczkowski Martin Filipits Reinhard Horvat Bellinda Benhamú María Luz López-Rodríguez Asha Leisser Peter Valent Michael Grusch Fausto G Hegardt Jordi García Dolors Serra Nelly Auersperg Ramón Colomer Thomas W Grunt

Int J Cancer 2015 May 3;136(9):2078-90. Epub 2014 Nov 3.

Signaling Networks Program, Division of Oncology, Department of Medicine I, Medical University Vienna, Vienna, Austria; Comprehensive Cancer Center, Medical University Vienna, Vienna, Austria.

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http://dx.doi.org/10.1002/ijc.29261DOI Listing
May 2015

Distinct Epidemiology and Clinical Consequence of Classic Versus Rare EGFR Mutations in Lung Adenocarcinoma.

Authors:
Zoltan Lohinai Mir Alireza Hoda Katalin Fabian Gyula Ostoros Erzsebet Raso Tamas Barbai Jozsef Timar Ilona Kovalszky Mihaly Cserepes Anita Rozsas Viktoria Laszlo Michael Grusch Walter Berger Walter Klepetko Judit Moldvay Balazs Dome Balazs Hegedus

J Thorac Oncol 2015 May;10(5):738-46

*Department of Tumor Biology, National Koranyi Institute of Pulmonology, Budapest, Hungary; †Translational Thoracic Oncology Laboratory, Division of Thoracic Surgery, Department of Surgery, Comprehensive Cancer Center, Medical University of Vienna, Austria; ‡Department of Thoracic Surgery, National Institute of Oncology-Semmelweis University; §Department of Pulmonology, ‖Second Department of Pathology, Semmelweis University; ¶Molecular Oncology Research Group, Hungarian Academy of Sciences-Semmelweis University, Budapest, Hungary; #First Department of Pathology, Experimental Cancer Research, Semmelweis University, Budapest, Hungary; and ** Department of Internal Medicine I, Institute of Cancer Research and Comprehensive Cancer Center, Medical University of Vienna, Austria.

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http://dx.doi.org/10.1097/JTO.0000000000000492DOI Listing
May 2015

Activin A is anti-lymphangiogenic in a melanoma mouse model.

Authors:
Magdalena Heinz Heide Leb Niederleithner Emmi Puujalka Ana Soler-Cardona Michael Grusch Hubert Pehamberger Robert Loewe Peter Petzelbauer

J Invest Dermatol 2015 Jan 1;135(1):212-221. Epub 2014 Aug 1.

Skin & Endothelium Research Division SERD, Department of Dermatology, Medical University of Vienna, Vienna, Austria; Division of General Dermatology, Department of Dermatology, Medical University of Vienna, Vienna, Austria. Electronic address:

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http://dx.doi.org/10.1038/jid.2014.328DOI Listing
January 2015

The effect of organic anion-transporting polypeptides 1B1, 1B3 and 2B1 on the antitumor activity of flavopiridol in breast cancer cells.

Authors:
Stefan Brenner Juliane Riha Benedikt Giessrigl Theresia Thalhammer Michael Grusch Georg Krupitza Bruno Stieger Walter Jäger

Int J Oncol 2015 Jan 24;46(1):324-32. Epub 2014 Oct 24.

Department of Clinical Pharmacy and Diagnostics, University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.3892/ijo.2014.2731DOI Listing
January 2015

Lobatin B inhibits NPM/ALK and NF-κB attenuating anaplastic-large-cell-lymphomagenesis and lymphendothelial tumour intravasation.

Authors:
Izabella Kiss Christine Unger Chi Nguyen Huu Atanas Georgiev Atanasov Nina Kramer Waranya Chatruphonprasert Stefan Brenner Ruxandra McKinnon Andrea Peschel Andrea Vasas Ildiko Lajter Renate Kain Philipp Saiko Thomas Szekeres Lukas Kenner Melanie R Hassler Rene Diaz Richard Frisch Verena M Dirsch Walter Jäger Rainer de Martin Valery N Bochkov Claus M Passreiter Barbara Peter-Vörösmarty Robert M Mader Michael Grusch Helmut Dolznig Brigitte Kopp Istvan Zupko Judit Hohmann Georg Krupitza

Cancer Lett 2015 Jan 15;356(2 Pt B):994-1006. Epub 2014 Nov 15.

Clinical Institute of Pathology, Medical University of Vienna, Waehringer Guertel 18-20, A-1090 Vienna, Austria. Electronic address:

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http://dx.doi.org/10.1016/j.canlet.2014.11.019DOI Listing
January 2015

Epigallocatechin gallate, ellagic acid, and rosmarinic acid perturb dNTP pools and inhibit de novo DNA synthesis and proliferation of human HL-60 promyelocytic leukemia cells: Synergism with arabinofuranosylcytosine.

Authors:
Philipp Saiko Marie-Thérèse Steinmann Heike Schuster Geraldine Graser Sabine Bressler Benedikt Giessrigl Andreas Lackner Michael Grusch Georg Krupitza Zsuzsanna Bago-Horvath Walter Jaeger Monika Fritzer-Szekeres Thomas Szekeres

Phytomedicine 2015 Jan 3;22(1):213-22. Epub 2014 Dec 3.

Department of Medical and Chemical Laboratory Diagnostics, Medical University of Vienna, Waehringer Guertel 18-20, A-1090 Vienna, Austria. Electronic address:

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http://dx.doi.org/10.1016/j.phymed.2014.11.017DOI Listing
January 2015

Fibroblast growth factor receptor 4: a putative key driver for the aggressive phenotype of hepatocellular carcinoma.

Authors:
Christine Gauglhofer Jakob Paur Waltraud C Schrottmaier Bettina Wingelhofer Daniela Huber Isabelle Naegelen Christine Pirker Thomas Mohr Christine Heinzle Klaus Holzmann Brigitte Marian Rolf Schulte-Hermann Walter Berger Georg Krupitza Michael Grusch Bettina Grasl-Kraupp

Carcinogenesis 2014 Oct 16;35(10):2331-8. Epub 2014 Jul 16.

Department of Medicine I, Division: Institute of Cancer Research, Comprehensive Cancer Center, Medical University of Vienna, Borschkegasse 8a, A-1090 Vienna, Austria and Institute of Clinical Pathology, Medical University of Vienna, Waehringer Guertel 18-20, A-1090 Vienna, Austria

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http://carcin.oxfordjournals.org/content/35/10/2331.full.pdf
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http://dx.doi.org/10.1093/carcin/bgu151DOI Listing
October 2014

Fibroblast growth factor receptor inhibition is active against mesothelioma and synergizes with radio- and chemotherapy.

Authors:
Karin Schelch Mir A Hoda Thomas Klikovits Julia Münzker Bahil Ghanim Christina Wagner Tamas Garay Viktoria Laszlo Ulrike Setinek Balazs Dome Martin Filipits Christine Pirker Petra Heffeter Edgar Selzer Jozsef Tovari Szilvia Torok Istvan Kenessey Klaus Holzmann Bettina Grasl-Kraupp Brigitte Marian Walter Klepetko Walter Berger Balazs Hegedus Michael Grusch

Am J Respir Crit Care Med 2014 Oct;190(7):763-72

1 Translational Thoracic Oncology Laboratory, Division of Thoracic Surgery, Department of Surgery, and.

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http://dx.doi.org/10.1164/rccm.201404-0658OCDOI Listing
October 2014

Spatio-temporally precise activation of engineered receptor tyrosine kinases by light.

Authors:
Michael Grusch Karin Schelch Robert Riedler Eva Reichhart Christopher Differ Walter Berger Álvaro Inglés-Prieto Harald Janovjak

EMBO J 2014 Aug 1;33(15):1713-26. Epub 2014 Jul 1.

Institute of Science and Technology Austria (IST Austria), Klosterneuburg, Austria

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http://dx.doi.org/10.15252/embj.201387695DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4194103PMC
August 2014

Subtype-specific KRAS mutations in advanced lung adenocarcinoma: a retrospective study of patients treated with platinum-based chemotherapy.

Authors:
Mihaly Cserepes Gyula Ostoros Zoltan Lohinai Erzsebet Raso Tamas Barbai Jozsef Timar Anita Rozsas Judit Moldvay Ilona Kovalszky Katalin Fabian Marton Gyulai Bahil Ghanim Viktoria Laszlo Thomas Klikovits Mir Alireza Hoda Michael Grusch Walter Berger Walter Klepetko Balazs Hegedus Balazs Dome

Eur J Cancer 2014 Jul 22;50(10):1819-1828. Epub 2014 Apr 22.

Department of Tumor Biology, National Koranyi Institute of Pulmonology, Budapest, Hungary; Division of Thoracic Surgery, Medical University of Vienna, Austria; Department of Thoracic Surgery, National Institute of Oncology-Semmelweis University, Budapest, Hungary. Electronic address:

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http://dx.doi.org/10.1016/j.ejca.2014.04.001DOI Listing
July 2014

Erythropoietin receptor expression is a potential prognostic factor in human lung adenocarcinoma.

Authors:
Anita Rózsás Judit Berta Lívia Rojkó László Z Horváth Magdolna Keszthelyi István Kenessey Viktória László Walter Berger Michael Grusch Mir Alireza Hoda Szilvia Török Walter Klepetko Ferenc Rényi-Vámos Balázs Hegedűs Balázs Döme József Tóvári

PLoS One 2013 14;8(10):e77459. Epub 2013 Oct 14.

Department of Tumor Biology, National Koranyi Institute of Pulmonology, Budapest, Hungary ; Division of Thoracic Surgery, Medical University of Vienna, Vienna, Austria.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0077459PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3796497PMC
June 2014

Apelin promotes lymphangiogenesis and lymph node metastasis.

Authors:
Judit Berta Mir Alireza Hoda Viktoria Laszlo Anita Rozsas Tamas Garay Szilvia Torok Michael Grusch Walter Berger Sandor Paku Ferenc Renyi-Vamos Bernard Masri Jozsef Tovari Marion Groger Walter Klepetko Balazs Hegedus Balazs Dome

Oncotarget 2014 Jun;5(12):4426-37

Division of Thoracic Surgery, Department of Surgery, Comprehensive Cancer Center, Medical University of Vienna, Austria; Department of Tumor Biology, National Koranyi Institute of Pulmonology, Budapest, Hungary; Thoracic Surgery, National Institute of Oncology and Semmelweis University, Budapest, Hungary.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4147335PMC
http://dx.doi.org/10.18632/oncotarget.2032DOI Listing
June 2014

Inhibition of tumour spheroid-induced prometastatic intravasation gates in the lymph endothelial cell barrier by carbamazepine: drug testing in a 3D model.

Authors:
Mathias Teichmann Nicole Kretschy Sabine Kopf Kanokwan Jarukamjorn Atanas G Atanasov Katharina Viola Benedikt Giessrigl Philipp Saiko Thomas Szekeres Wolfgang Mikulits Verena M Dirsch Nicole Huttary Sigurd Krieger Walter Jäger Michael Grusch Helmut Dolznig Georg Krupitza

Arch Toxicol 2014 Mar 19;88(3):691-9. Epub 2013 Dec 19.

Clinical Institute of Pathology, Medical University of Vienna, Waehringer Guertel 18-20, 1090, Vienna, Austria.

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http://dx.doi.org/10.1007/s00204-013-1183-5DOI Listing
March 2014

Major vault protein supports glioblastoma survival and migration by upregulating the EGFR/PI3K signalling axis.

Authors:
Daniela Lötsch Elisabeth Steiner Klaus Holzmann Sabine Spiegl-Kreinecker Christine Pirker Juraj Hlavaty Helga Petznek Balazs Hegedus Tamas Garay Thomas Mohr Wolfgang Sommergruber Michael Grusch Walter Berger

Oncotarget 2013 Nov;4(11):1904-18

Institute of Cancer Research, Department of Medicine I.

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http://www.oncotarget.com/fulltext/1264
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3875758PMC
http://dx.doi.org/10.18632/oncotarget.1264DOI Listing
November 2013

In vitro characterisation of the anti-intravasative properties of the marine product heteronemin.

Authors:
Sabine Kopf Katharina Viola Atanas G Atanasov Kanokwan Jarukamjorn Lucie Rarova Nicole Kretschy Mathias Teichmann Caroline Vonach Philipp Saiko Benedikt Giessrigl Nicole Huttary Ingrid Raab Sigurd Krieger Marc Schumacher Marc Diederich Miroslav Strnad Rainer de Martin Thomas Szekeres Walter Jäger Verena M Dirsch Wolfgang Mikulits Michael Grusch Helmut Dolznig Georg Krupitza

Arch Toxicol 2013 Oct 30;87(10):1851-61. Epub 2013 Mar 30.

Institute of Clinical Pathology, Medical University of Vienna, Waehringer Guertel 18-20, 1090, Vienna, Austria.

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http://dx.doi.org/10.1007/s00204-013-1045-1DOI Listing
October 2013

Digalloylresveratrol, a novel resveratrol analog inhibits the growth of human pancreatic cancer cells.

Authors:
Philipp Saiko Geraldine Graser Benedikt Giessrigl Marie-Thérèse Steinmann Heike Schuster Andreas Lackner Michael Grusch Georg Krupitza Walter Jaeger Venkateswarlu Somepalli Trimurtulu Golakoti Monika Fritzer-Szekeres Thomas Szekeres

Invest New Drugs 2013 Oct 14;31(5):1115-24. Epub 2013 Aug 14.

Department of Medical and Chemical Laboratory Diagnostics, Medical University of Vienna, Waehringer Guertel 18-20, 1090, Vienna, Austria.

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http://link.springer.com/content/pdf/10.1007/s10637-013-0009
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http://link.springer.com/10.1007/s10637-013-0009-x
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http://dx.doi.org/10.1007/s10637-013-0009-xDOI Listing
October 2013

Xanthohumol attenuates tumour cell-mediated breaching of the lymphendothelial barrier and prevents intravasation and metastasis.

Authors:
Katharina Viola Sabine Kopf Lucie Rarova Kanokwan Jarukamjorn Nicole Kretschy Mathias Teichmann Caroline Vonach Atanas G Atanasov Benedikt Giessrigl Nicole Huttary Ingrid Raab Sigurd Krieger Miroslav Strnad Rainer de Martin Philipp Saiko Thomas Szekeres Siegfried Knasmüller Verena M Dirsch Walter Jäger Michael Grusch Helmut Dolznig Wolfgang Mikulits Georg Krupitza

Arch Toxicol 2013 Jul 17;87(7):1301-12. Epub 2013 Mar 17.

Institute of Clinical Pathology, Medical University of Vienna, Waehringer Guertel 18-20, 1090 Vienna, Austria.

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http://dx.doi.org/10.1007/s00204-013-1028-2DOI Listing
July 2013

Synergistic effects of erlotinib and everolimus on bronchial carcinoids and large-cell neuroendocrine carcinomas with activated EGFR/AKT/mTOR pathway.

Authors:
Zsuzsanna Bago-Horvath Wolfgang Sieghart Michael Grusch Andreas Lackner Hubert Hayden Christine Pirker Oxana Komina Józefa Węsierska-Gądek Andrea Haitel Martin Filipits Walter Berger Katharina Schmid

Neuroendocrinology 2012 27;96(3):228-37. Epub 2012 Apr 27.

Clinical Institute of Pathology, Medical University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.1159/000337257DOI Listing
May 2013

The dichloromethane extract of the ethnomedicinal plant Neurolaena lobata inhibits NPM/ALK expression which is causal for anaplastic large cell lymphomagenesis.

Authors:
Christine Unger Ruxandra Popescu Benedikt Giessrigl Daniela Laimer Susanne Heider Mareike Seelinger Rene Diaz Bruno Wallnöfer Gerda Egger Melanie Hassler Martin Knöfler Leila Saleh Emine Sahin Michael Grusch Monika Fritzer-Szekeres Helmut Dolznig Richard Frisch Lukas Kenner Brigitte Kopp Georg Krupitza

Int J Oncol 2013 Jan 6;42(1):338-48. Epub 2012 Nov 6.

Clinical Institute of Pathology, Medical University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.3892/ijo.2012.1690DOI Listing
January 2013

Differential effects of polymorphic alleles of FGF receptor 4 on colon cancer growth and metastasis.

Authors:
Christine Heinzle Andrea Gsur Monika Hunjadi Zeynep Erdem Christine Gauglhofer Stefan Stättner Josef Karner Martin Klimpfinger Friedrich Wrba Andrea Reti Balazs Hegedus Andreas Baierl Bettina Grasl-Kraupp Klaus Holzmann Michael Grusch Walter Berger Brigitte Marian

Cancer Res 2012 Nov 12;72(22):5767-77. Epub 2012 Sep 12.

Department of Medicine 1, Institute of Cancer Research, Clinical Institute of Pathology, University of Vienna, Vienna, Austria.

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http://cancerres.aacrjournals.org/cgi/doi/10.1158/0008-5472.
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http://dx.doi.org/10.1158/0008-5472.CAN-11-3654DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5455878PMC
November 2012

Pretreatment serum C-reactive protein levels predict benefit from multimodality treatment including radical surgery in malignant pleural mesothelioma: a retrospective multicenter analysis.

Authors:
Bahil Ghanim Mir Alireza Hoda Max-Paul Winter Thomas Klikovits Arman Alimohammadi Balazs Hegedus Balazs Dome Michael Grusch Madeleine Arns Peter Schenk Wolfgang Pohl Christoph Zielinski Martin Filipits Walter Klepetko Walter Berger

Ann Surg 2012 Aug;256(2):357-62

Division of Thoracic Surgery, Department of Surgery, Medical University of Vienna, Austria.

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http://dx.doi.org/10.1097/SLA.0b013e3182602af4DOI Listing
August 2012

The major vault protein mediates resistance to epidermal growth factor receptor inhibition in human hepatoma cells.

Authors:
Annemarie Losert Daniela Lötsch Andreas Lackner Herwig Koppensteiner Barbara Peter-Vörösmarty Elisabeth Steiner Klaus Holzmann Thomas Grunt Katharina Schmid Brigitte Marian Bettina Grasl-Kraupp Rolf Schulte-Hermann Georg Krupitza Walter Berger Michael Grusch

Cancer Lett 2012 Jun 17;319(2):164-172. Epub 2012 Jan 17.

Institute of Cancer Research, Department of Medicine I, Comprehensive Cancer Center, Medical University of Vienna, Borschkegasse 8a, A-1090 Vienna, Austria. Electronic address:

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http://linkinghub.elsevier.com/retrieve/pii/S030438351200027
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http://dx.doi.org/10.1016/j.canlet.2012.01.002DOI Listing
June 2012

Effects of Scrophularia extracts on tumor cell proliferation, death and intravasation through lymphoendothelial cell barriers.

Authors:
Benedikt Giessrigl Gökhan Yazici Mathias Teichmann Sabine Kopf Sara Ghassemi Atanas G Atanasov Verena M Dirsch Michael Grusch Walter Jäger Ali Ozmen Georg Krupitza

Int J Oncol 2012 Jun 22;40(6):2063-74. Epub 2012 Feb 22.

Institute of Clinical Pathology, Medical University of Vienna, A-1090 Vienna, Austria.

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http://dx.doi.org/10.3892/ijo.2012.1388DOI Listing
June 2012

An apolar extract of Critonia morifolia inhibits c-Myc, cyclin D1, Cdc25A, Cdc25B, Cdc25C and Akt and induces apoptosis.

Authors:
Christine Unger Ruxandra Popescu Benedikt Giessrigl Lucie Rarova Irene Herbacek Mareike Seelinger Rene Diaz Bruno Wallnöfer Monika Fritzer-Szekeres Thomas Szekeres Richard Frisch Karel Doležal Miroslav Strnad Rainer De Martin Michael Grusch Brigitte Kopp Georg Krupitza

Int J Oncol 2012 Jun 23;40(6):2131-9. Epub 2012 Mar 23.

Institute of Clinical Pathology, Medical University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.3892/ijo.2012.1412DOI Listing
June 2012

Aggressiveness of human melanoma xenograft models is promoted by aneuploidy-driven gene expression deregulation.

Authors:
Véronique Mathieu Christine Pirker Wolfgang M Schmidt Sabine Spiegl-Kreinecker Daniela Lötsch Petra Heffeter Balazs Hegedus Michael Grusch Robert Kiss Walter Berger

Oncotarget 2012 Apr;3(4):399-413

Laboratory of Toxicology, Faculty of Pharmacy, Université Libre de Bruxelles, Brussels, Belgium.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3380575PMC
http://dx.doi.org/10.18632/oncotarget.473DOI Listing
April 2012

Stable protein expression in mammalian cells using baculoviruses.

Authors:
Andreas Lackner Emanuel Kreidl Barbara Peter-Vörösmarty Sabine Spiegl-Kreinecker Walter Berger Michael Grusch

Methods Mol Biol 2012 ;801:75-92

Department of Medicine I, Institute of Cancer Research, Medical University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.1007/978-1-61779-352-3_6DOI Listing
February 2012

Fibroblast growth factor receptors as therapeutic targets in human melanoma: synergism with BRAF inhibition.

Authors:
Thomas Metzner Alexandra Bedeir Gerlinde Held Barbara Peter-Vörösmarty Sara Ghassemi Christine Heinzle Sabine Spiegl-Kreinecker Brigitte Marian Klaus Holzmann Bettina Grasl-Kraupp Christine Pirker Michael Micksche Walter Berger Petra Heffeter Michael Grusch

J Invest Dermatol 2011 Oct 14;131(10):2087-95. Epub 2011 Jul 14.

Department of Medicine I, Comprehensive Cancer Center, Institute of Cancer Research, Medical University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.1038/jid.2011.177DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3383623PMC
October 2011

The PI3 kinase/mTOR blocker NVP-BEZ235 overrides resistance against irreversible ErbB inhibitors in breast cancer cells.

Authors:
Caroline Brünner-Kubath Waheed Shabbir Victoria Saferding Renate Wagner Christian F Singer Peter Valent Walter Berger Brigitte Marian Christoph C Zielinski Michael Grusch Thomas W Grunt

Breast Cancer Res Treat 2011 Sep 3;129(2):387-400. Epub 2010 Nov 3.

Signaling Networks Program, Division of Oncology, Department of Medicine I, Medical University Vienna, Waehringer Guertel 18-20, 1090, Vienna, Austria.

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http://dx.doi.org/10.1007/s10549-010-1232-1DOI Listing
September 2011

EGCG-meditated cyto- and genotoxicity in HaCat keratinocytes is impaired by cell-mediated clearance of auto-oxidation-derived H2O2: an algorithm for experimental setting correction.

Authors:
Leonilla Elbling Irene Herbacek Rosa-Maria Weiss Christopher Gerner Petra Heffeter Christian Jantschitsch Franz Trautinger Michael Grusch Heinrich Pangratz Walter Berger

Toxicol Lett 2011 Aug 15;205(2):173-82. Epub 2011 Jun 15.

Department of Medicine I, Institute of Cancer Research, Medical University Vienna, Borschkegasse 8a, 1090 Vienna, Austria.

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http://dx.doi.org/10.1016/j.toxlet.2011.06.001DOI Listing
August 2011

Targeting fibroblast-growth-factor-receptor-dependent signaling for cancer therapy.

Authors:
Christine Heinzle Hedwig Sutterlüty Michael Grusch Bettina Grasl-Kraupp Walter Berger Brigitte Marian

Expert Opin Ther Targets 2011 Jul 7;15(7):829-46. Epub 2011 Mar 7.

Medical University Vienna, Institute of Cancer Research, Department of Medicine 1, Vienna,Austria.

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http://dx.doi.org/10.1517/14728222.2011.566217DOI Listing
July 2011

Temsirolimus inhibits malignant pleural mesothelioma growth in vitro and in vivo: synergism with chemotherapy.

Authors:
Mir Alireza Hoda Amir Mohamed Bahil Ghanim Martin Filipits Balazs Hegedus Masaya Tamura Judit Berta Bernd Kubista Balazs Dome Michael Grusch Ulrike Setinek Michael Micksche Walter Klepetko Walter Berger

J Thorac Oncol 2011 May;6(5):852-63

Division of Thoracic Surgery, Department of Surgery, Medical University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.1097/JTO.0b013e31820e1a25DOI Listing
May 2011

Up-regulation of the fibroblast growth factor 8 subfamily in human hepatocellular carcinoma for cell survival and neoangiogenesis.

Authors:
Christine Gauglhofer Sandra Sagmeister Waltraud Schrottmaier Carina Fischer Chantal Rodgarkia-Dara Thomas Mohr Stefan Stättner Christoph Bichler Daniela Kandioler Fritz Wrba Rolf Schulte-Hermann Klaus Holzmann Michael Grusch Brigitte Marian Walter Berger Bettina Grasl-Kraupp

Hepatology 2011 Mar 11;53(3):854-64. Epub 2011 Feb 11.

Institute of Cancer Research, Comprehensive Cancer Center, Department of Medicine I, Medical University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.1002/hep.24099DOI Listing
March 2011

A novel N-hydroxy-N'-aminoguanidine derivative inhibits ribonucleotide reductase activity: Effects in human HL-60 promyelocytic leukemia cells and synergism with arabinofuranosylcytosine (Ara-C).

Authors:
Philipp Saiko Geraldine Graser Benedikt Giessrigl Andreas Lackner Michael Grusch Georg Krupitza Arijit Basu Barij Nayan Sinha Venkatesan Jayaprakash Walter Jaeger Monika Fritzer-Szekeres Thomas Szekeres

Biochem Pharmacol 2011 Jan 16;81(1):50-9. Epub 2010 Sep 16.

Department of Medical and Chemical Laboratory Diagnostics, Medical University of Vienna, General Hospital of Vienna, Waehringer Guertel 18-20, A-1090 Vienna, Austria.

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http://dx.doi.org/10.1016/j.bcp.2010.09.006DOI Listing
January 2011

Pro- and anticarcinogenic mechanisms of piceatannol are activated dose dependently in MCF-7 breast cancer cells.

Authors:
Nha T P Vo Sibylle Madlener Zsuzsanna Bago-Horvath Irene Herbacek Nicole Stark Manuela Gridling Paul Probst Benedikt Giessrigl Sabine Bauer Caroline Vonach Philipp Saiko Michael Grusch Thomas Szekeres Monika Fritzer-Szekeres Walter Jäger Georg Krupitza Afschin Soleiman

Carcinogenesis 2010 Dec 20;31(12):2074-81. Epub 2009 Aug 20.

Institute of Clinical Pathology, Medical University of Vienna, Waehringer Guertel 18-20, A-1090 Vienna, Austria.

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http://dx.doi.org/10.1093/carcin/bgp199DOI Listing
December 2010

The crosstalk of RAS with the TGF-β family during carcinoma progression and its implications for targeted cancer therapy.

Authors:
Michael Grusch Michaela Petz Thomas Metzner Deniz Oztürk Doris Schneller Wolfgang Mikulits

Curr Cancer Drug Targets 2010 Dec;10(8):849-57

Department of Medicine I, Division, Institute of Cancer Research, Medical University of Vienna, Borschke-Gasse 8a, A-1090 Vienna, Austria.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3044462PMC
http://dx.doi.org/10.2174/156800910793357943DOI Listing
December 2010

Response of experimental malignant melanoma models to the pan-Aurora kinase inhibitor VE-465.

Authors:
Christine Pirker Daniela Lötsch Sabine Spiegl-Kreinecker Florian Jantscher Hewig Sutterlüty Michael Micksche Michael Grusch Walter Berger

Exp Dermatol 2010 Dec;19(12):1040-7

Institute of Cancer Research, Clinics for Medicine I, Medical University Vienna, Vienna, Austria.

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http://dx.doi.org/10.1111/j.1600-0625.2010.01182.xDOI Listing
December 2010

Hydrogen peroxide mediates EGCG-induced antioxidant protection in human keratinocytes.

Authors:
Leonilla Elbling Irene Herbacek Rosa-Maria Weiss Christian Jantschitsch Michael Micksche Christopher Gerner Heinrich Pangratz Michael Grusch Siegfried Knasmüller Walter Berger

Free Radic Biol Med 2010 Nov 12;49(9):1444-52. Epub 2010 Aug 12.

Institute of Cancer Research, Department of Medicine I, Medical University of Vienna, 1090 Vienna, Austria.

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http://dx.doi.org/10.1016/j.freeradbiomed.2010.08.008DOI Listing
November 2010

Bimodal expression of Sprouty2 during the cell cycle is mediated by phase-specific Ras/MAPK and c-Cbl activities.

Authors:
Christoph-Erik Mayer Barbara Haigl Florian Jantscher Gerald Siegwart Michael Grusch Walter Berger Hedwig Sutterlüty

Cell Mol Life Sci 2010 Oct 12;67(19):3299-311. Epub 2010 May 12.

Department of Medicine I, Institute of Cancer Research, Medical University of Vienna, Borschkegasse 8a, 1090 Vienna, Austria.

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http://dx.doi.org/10.1007/s00018-010-0379-6DOI Listing
October 2010

Indications for cell stress in response to adenoviral and baculoviral gene transfer observed by proteome profiling of human cancer cells.

Authors:
Christopher Gerner Verena J Haudek-Prinz Andreas Lackner Annemarie Losert Barbara Peter-Vörösmarty Olga Lorenz Michael Grusch

Electrophoresis 2010 Jun;31(11):1822-32

Department of Medicine I, Division: Institute of Cancer Research, Medical University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.1002/elps.200900753DOI Listing
June 2010

Cell characterization by proteome profiling applied to primary hepatocytes and hepatocyte cell lines Hep-G2 and Hep-3B.

Authors:
Astrid Slany Verena J Haudek Hannes Zwickl Nina C Gundacker Michael Grusch Thomas S Weiss Katja Seir Chantal Rodgarkia-Dara Claus Hellerbrand Christopher Gerner

J Proteome Res 2010 Jan;9(1):6-21

Department of Medicine I, Institute of Cancer Research, Medical University of Vienna, Austria.

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http://dx.doi.org/10.1021/pr900057tDOI Listing
January 2010

Berberine and a Berberis lycium extract inactivate Cdc25A and induce alpha-tubulin acetylation that correlate with HL-60 cell cycle inhibition and apoptosis.

Authors:
Musa Khan Benedikt Giessrigl Caroline Vonach Sibylle Madlener Sonja Prinz Irene Herbaceck Christine Hölzl Sabine Bauer Katharina Viola Wolfgang Mikulits Rizwana Aleem Quereshi Siegfried Knasmüller Michael Grusch Brigitte Kopp Georg Krupitza

Mutat Res 2010 Jan;683(1-2):123-30

Department of Plant Sciences, Quaid-i-Azam University, Islamabad, Pakistan.

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http://linkinghub.elsevier.com/retrieve/pii/S002751070900346
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http://dx.doi.org/10.1016/j.mrfmmm.2009.11.001DOI Listing
January 2010

Antitumor effects of KITC, a new resveratrol derivative, in AsPC-1 and BxPC-3 human pancreatic carcinoma cells.

Authors:
Astrid Bernhaus Maria Ozsvar-Kozma Philipp Saiko Margit Jaschke Andreas Lackner Michael Grusch Zsuzsanna Horvath Sibylle Madlener Georg Krupitza Norbert Handler Thomas Erker Walter Jaeger Monika Fritzer-Szekeres Thomas Szekeres

Invest New Drugs 2009 Oct 8;27(5):393-401. Epub 2008 Oct 8.

Clinical Institute of Medical and Chemical Laboratory Diagnostics, General Hospital of Vienna, Medical University of Vienna, Waehringer Guertel 18-20, A-1090, Vienna, Austria.

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http://link.springer.com/10.1007/s10637-008-9183-7
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http://dx.doi.org/10.1007/s10637-008-9183-7DOI Listing
October 2009

A polar extract of the Maya healing plant Anthurium schlechtendalii (Aracea) exhibits strong in vitro anticancer activity.

Authors:
Nicole Stark Manuela Gridling Sibylle Madlener Sabine Bauer Andreas Lackner Ruxandra Popescu Rene Diaz Foster M Tut Thanh-Phuong Nha Vo Caroline Vonach Benedikt Giessrigl Philipp Saiko Michael Grusch Monika Fritzer-Szekeres Thomas Szekeres Brigitte Kopp Richard Frisch Georg Krupitza

Int J Mol Med 2009 Oct;24(4):513-21

Institute of Clinical Pathology, Medical University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.3892/ijmm_00000260DOI Listing
October 2009

In vitro anti-inflammatory and anticancer activities of extracts of Acalypha alopecuroidea (Euphorbiaceae).

Authors:
Sibylle Madlener Jana Svacinová Miloslav Kitner Jirí Kopecky Ruth Eytner Andreas Lackner Than Phuong Nha Vo Richard Frisch Michael Grusch Rainer De Martin Karel Dolezal Miroslav Strnad Georg Krupitza

Int J Oncol 2009 Oct;35(4):881-91

Institute of Clinical Pathology, Medical University of Vienna, A-1090 Vienna, Austria.

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http://dx.doi.org/10.3892/ijo_00000403DOI Listing
October 2009

Activins and follistatins: Emerging roles in liver physiology and cancer.

Authors:
Emanuel Kreidl Deniz Oztürk Thomas Metzner Walter Berger Michael Grusch

World J Hepatol 2009 Oct;1(1):17-27

Emanuel Kreidl, Deniz Öztürk, Thomas Metzner, Walter Berger, Michael Grusch, Institute of Cancer Research, Department of Medicine I, Medical University of Vienna, Borschkegasse 8a, Vienna A-1090, Austria.

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http://dx.doi.org/10.4254/wjh.v1.i1.17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2999257PMC
October 2009

Interaction between fatty acid synthase- and ErbB-systems in ovarian cancer cells.

Authors:
Thomas W Grunt Renate Wagner Michael Grusch Walter Berger Christian F Singer Brigitte Marian Christoph C Zielinski Ruth Lupu

Biochem Biophys Res Commun 2009 Jul 23;385(3):454-9. Epub 2009 May 23.

Signaling Networks Program, Department of Medicine I, Medical University Vienna, Vienna, Austria.

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http://dx.doi.org/10.1016/j.bbrc.2009.05.085DOI Listing
July 2009

Short 42 degrees C heat shock induces phosphorylation and degradation of Cdc25A which depends on p38MAPK, Chk2 and 14.3.3.

Authors:
Sibylle Madlener Margit Rosner Sigurd Krieger Benedikt Giessrigl Manuela Gridling Thanh Phuong Nha Vo Christina Leisser Andreas Lackner Ingrid Raab Michael Grusch Markus Hengstschläger Helmut Dolznig Georg Krupitza

Hum Mol Genet 2009 Jun 16;18(11):1990-2000. Epub 2009 Mar 16.

Institute of Clinical Pathology, Medical University of Vienna, Austria.

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http://dx.doi.org/10.1093/hmg/ddp123DOI Listing
June 2009

Microscopic analysis of adenoviral decontamination using GFP adenovirus with comparable sensitivity to flow cytometry.

Authors:
Michael Grusch Annemarie Losert Andreas Lackner Alev Deli Irene Herbacek Klaus Holzmann

Methods Mol Biol 2009 ;515:125-35

Department of Medicine I, Radical University of Vienna, Borschkepasse 8a, 1090, Vienna, Austria.

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http://dx.doi.org/10.1007/978-1-59745-559-6_8DOI Listing
May 2009

In vitro anti-cancer activity of two ethno-pharmacological healing plants from Guatemala Pluchea odorata and Phlebodium decumanum.

Authors:
Manuela Gridling Nicole Stark Sibylle Madlener Andreas Lackner Ruxandra Popescu Birgit Benedek Rene Diaz Foster M Tut Thanh Phuong Nha Vo Daniela Huber Michaela Gollinger Philipp Saiko Ali Ozmen Wilhelm Mosgoeller Rainer De Martin Ruth Eytner Karl-Heinz Wagner Michael Grusch Monika Fritzer-Szekeres Thomas Szekeres Brigitte Kopp Richard Frisch Georg Krupitza

Int J Oncol 2009 Apr;34(4):1117-28

Institute of Clinical Pathology, Medical University of Vienna, A-1090 Vienna, Austria.

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http://dx.doi.org/10.3892/ijo_00000239DOI Listing
April 2009

Avemar, a nontoxic fermented wheat germ extract, attenuates the growth of sensitive and 5-FdUrd/Ara-C cross-resistant H9 human lymphoma cells through induction of apoptosis.

Authors:
Philipp Saiko Maria Ozsvar-Kozma Geraldine Graser Andreas Lackner Michael Grusch Sibylle Madlener Georg Krupitza Walter Jaeger Mate Hidvegi Ram P Agarwal Monika Fritzer-Szekeres Thomas Szekeres

Oncol Rep 2009 Mar;21(3):787-91

Clinical Institute of Medical and Chemical Laboratory Diagnostics, Medical University of Vienna, General Hospital of Vienna, A-1090 Vienna, Austria.

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March 2009

Digalloylresveratrol, a new phenolic acid derivative induces apoptosis and cell cycle arrest in human HT-29 colon cancer cells.

Authors:
Astrid Bernhaus Monika Fritzer-Szekeres Michael Grusch Philipp Saiko Georg Krupitza Somepalli Venkateswarlu Golakoti Trimurtulu Walter Jaeger Thomas Szekeres

Cancer Lett 2009 Feb 25;274(2):299-304. Epub 2008 Oct 25.

Clinical Institute of Medical and Chemical Laboratory Diagnostics, Medical University of Vienna, General Hospital of Vienna, Waehringer Guertel 18-20, A-1090 Vienna, Austria.

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http://dx.doi.org/10.1016/j.canlet.2008.09.020DOI Listing
February 2009

NORE1B is a putative tumor suppressor in hepatocarcinogenesis and may act via RASSF1A.

Authors:
Doris Macheiner Christine Gauglhofer Chantal Rodgarkia-Dara Michael Grusch Andreas Brachner Christoph Bichler Daniela Kandioler Hedwig Sutterlüty Wolfgang Mikulits Rolf Schulte-Hermann Bettina Grasl-Kraupp

Cancer Res 2009 Jan;69(1):235-42

Department of Medicine I, Division: Institute of Cancer Research, Medical University of Vienna, Borschkegasse 8a, Vienna, Austria.

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http://dx.doi.org/10.1158/0008-5472.CAN-08-2144DOI Listing
January 2009

Use of four new human-derived liver-cell lines for the detection of genotoxic compounds in the single-cell gel electrophoresis (SCGE) assay.

Authors:
Heike K Winter Veronika A Ehrlich Michael Grusch Andreas Lackner Rolf Schulte-Hermann Bettina Grasl-Kraupp Wolfgang Mikulits Siegfried Knasmüller

Mutat Res 2008 Dec 26;657(2):133-9. Epub 2008 Aug 26.

Institute of Cancer Research, Medical University of Vienna, Borschkegasse 8a, A-1090 Vienna, Austria.

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https://linkinghub.elsevier.com/retrieve/pii/S13835718080025
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http://dx.doi.org/10.1016/j.mrgentox.2008.08.012DOI Listing
December 2008

HB-EGF is a paracrine growth stimulator for early tumor prestages in inflammation-associated hepatocarcinogenesis.

Authors:
Sandra Sagmeister Claudia Drucker Annemarie Losert Michael Grusch Anahita Daryabeigi Wolfram Parzefall Nataliya Rohr-Udilova Christoph Bichler Bård Smedsrød Daniela Kandioler Thomas Grünberger Fritz Wrba Rolf Schulte-Hermann Bettina Grasl-Kraupp

J Hepatol 2008 Dec 7;49(6):955-64. Epub 2008 Oct 7.

Department of Medicine I, Division: Institute of Cancer Research, Medical University of Vienna, Borschkegasse 8a, A-1090 Vienna, Austria.

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http://dx.doi.org/10.1016/j.jhep.2008.06.031DOI Listing
December 2008

Biochemical effects of piceatannol in human HL-60 promyelocytic leukemia cells--synergism with Ara-C.

Authors:
Monika Fritzer-Szekeres Ivo Savinc Zsuzsanna Horvath Philipp Saiko Michael Pemberger Geraldine Graser Astrid Bernhaus Maria Ozsvar-Kozma Michael Grusch Walter Jaeger Thomas Szekeres

Int J Oncol 2008 Oct;33(4):887-92

Clinical Institute of Medical and Chemical Laboratory Diagnostics, Medical University of Vienna, General Hospital of Vienna, A-1090 Vienna, Austria.

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October 2008

Fibroblast growth factor receptor-mediated signals contribute to the malignant phenotype of non-small cell lung cancer cells: therapeutic implications and synergism with epidermal growth factor receptor inhibition.

Authors:
Hendrik Fischer Ninon Taylor Sigrid Allerstorfer Michael Grusch Gudrun Sonvilla Klaus Holzmann Ulrike Setinek Leonilla Elbling Heidelinde Cantonati Bettina Grasl-Kraupp Christine Gauglhofer Brigitte Marian Michael Micksche Walter Berger

Mol Cancer Ther 2008 Oct;7(10):3408-19

Institute of Cancer Research, Department of Medicine I, Medical University Vienna, Vienna, Austria.

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http://mct.aacrjournals.org/lookup/doi/10.1158/1535-7163.MCT
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http://dx.doi.org/10.1158/1535-7163.MCT-08-0444DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2879863PMC
October 2008

A bicistronic baculovirus vector for transient and stable protein expression in mammalian cells.

Authors:
Andreas Lackner Kathrin Genta Herwig Koppensteiner Irene Herbacek Klaus Holzmann Sabine Spiegl-Kreinecker Walter Berger Michael Grusch

Anal Biochem 2008 Sep 22;380(1):146-8. Epub 2008 May 22.

Department of Medicine I, Institute of Cancer Research, Medical University of Vienna, A-1090 Vienna, Austria.

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http://dx.doi.org/10.1016/j.ab.2008.05.020DOI Listing
September 2008

Novel resveratrol analogs induce apoptosis and cause cell cycle arrest in HT29 human colon cancer cells: inhibition of ribonucleotide reductase activity.

Authors:
Philipp Saiko Michael Pemberger Zsuzsanna Horvath Ivo Savinc Michael Grusch Norbert Handler Thomas Erker Walter Jaeger Monika Fritzer-Szekeres Thomas Szekeres

Oncol Rep 2008 Jun;19(6):1621-6

Clinical Institute of Medical and Chemical Laboratory Diagnostics, Medical University of Vienna, Vienna, Austria.

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June 2008

Effects of coffee and its chemopreventive components kahweol and cafestol on cytochrome P450 and sulfotransferase in rat liver.

Authors:
Wolfgang W Huber Walter Rossmanith Michael Grusch Elisabeth Haslinger Sonja Prustomersky Barbara Peter-Vörösmarty Wolfram Parzefall Gerlinde Scharf Rolf Schulte-Hermann

Food Chem Toxicol 2008 Apr 25;46(4):1230-8. Epub 2007 Sep 25.

Research Unit of Toxicology and Prevention, Division Institute of Cancer Research, Department of Medicine I, Medical University of Vienna, Borschkegasse 8A, A-1090 Vienna, Austria.

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http://ac.els-cdn.com/S0278691507004437/1-s2.0-S027869150700
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http://linkinghub.elsevier.com/retrieve/pii/S027869150700443
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http://dx.doi.org/10.1016/j.fct.2007.09.094DOI Listing
April 2008

Activins and activin antagonists in hepatocellular carcinoma.

Authors:
Alev Deli Emanuel Kreidl Stefan Santifaller Barbara Trotter Katja Seir Walter Berger Rolf Schulte-Hermann Chantal Rodgarkia-Dara Michael Grusch

World J Gastroenterol 2008 Mar;14(11):1699-709

Institute of Cancer Research, Department of Medicine I, Medical University of Vienna, Borschkegasse 8a, Vienna A-1090, Austria.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2695910PMC
http://dx.doi.org/10.3748/wjg.14.1699DOI Listing
March 2008

Synergistic effects of deuterium oxide and gemcitabine in human pancreatic cancer cell lines.

Authors:
Yvonne Bader Johannes Hartmann Zsuzsanna Horvath Philipp Saiko Michael Grusch Sibylle Madlener Susanne Maier Leopold Oehler Monika Fritzer-Szekeres Nicole Heller Rudolf-Giesbert Alken Georg Krupitza Thomas Szekeres

Cancer Lett 2008 Feb 26;259(2):231-9. Epub 2007 Nov 26.

Clinical Institute of Medical and Chemical Laboratory Diagnostics, Medical University of Vienna, General Hospital of Vienna, Waehringer Guertel 18-20, A-1090 Vienna, Austria.

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http://dx.doi.org/10.1016/j.canlet.2007.10.010DOI Listing
February 2008

Novel resveratrol derivatives induce apoptosis and cause cell cycle arrest in prostate cancer cell lines.

Authors:
Zsuzsanna Horvath Sybille Marihart-Fazekas Philipp Saiko Michael Grusch Mehmet Ozsüy Mike Harik Norbert Handler Thomas Erker Walter Jaeger Monika Fritzer-Szekeres Bob Djavan Thomas Szekeres

Anticancer Res 2007 Sep-Oct;27(5A):3459-64

Clinical Institute of Medical and Chemical Laboratory Diagnostics, Waehringer Guertel 18-20, A-1090, Vienna, Austria.

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November 2007