Michael Grotzer

Michael Grotzer

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Michael Grotzer

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Cerebellar tumors.

Handb Clin Neurol 2018 ;155:289-299

Department of Oncology and Children's Research Center, University Children's Hospital Zurich, Zurich, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/B978-0-444-64189-2.00019-6DOI Listing
October 2018

Clinical, Radiologic, Pathologic, and Molecular Characteristics of Long-Term Survivors of Diffuse Intrinsic Pontine Glioma (DIPG): A Collaborative Report From the International and European Society for Pediatric Oncology DIPG Registries.

J Clin Oncol 2018 07 10;36(19):1963-1972. Epub 2018 May 10.

Lindsey M. Hoffman and Nicholas K. Foreman, University of Colorado Denver; Lindsey M. Hoffman and Nicholas K. Foreman, Children's Hospital Colorado, Aurora, CO; Sophie E.M. Veldhuijzen van Zanten, Esther Hulleman, Gertjan J.L. Kaspers, Esther Sanchez, and Dannis G. van Vuurden, Vrije Universiteit University Medical Center, Amsterdam; William P. Vandertop, Academy of Princess Máxima Center for Pediatric Oncology, Utrecht, the Netherlands; Niclas Colditz, Marion Hoffmann, Brigitte Bison, Monika Warmuth-Metz, and Christof M. Kramm, University Medical Center Goettingen, Goettingen; Torsten Pietsch and Gerrit H. Gielen, University of Bonn Medical Center, Bonn; David T.W. Jones, Dominik Sturm, Stefan M. Pfister, and Elke Pfaff, German Cancer Research Center, Hopp-Children's Cancer Center at the Nationale Centrum für Tumorerkrankungen Heidelberg, and German Consortium for Translational Cancer Research; Dominik Sturm, Stefan M. Pfister, and Elke Pfaff, Heidelberg University Hospital, Heidelberg, Germany; Joshua Baugh, Brooklyn Chaney, Adam Lane, Christine Fuller, Nancy Yanez Escorza, Renee Doughman, Rachid Drissi, James Leach, Blaise Jones, and Maryam Fouladi, Cincinnati Children's Hospital Medical Center, Cincinnati; Emmett Broxson, Wright State University and The Children's Medical Center, Dayton, OH; Lili Miles, Nemours Children's Hospital, Orlando, FL; Cynthia Hawkins, Ute Bartels, and Eric Bouffet, The Hospital for Sick Children, Toronto, Ontario; Anne Sophie Carret, Centre Hospitalier Universitaire Sainte-Justine; Nada Jabado, McGill University, Montreal, Quebec, Canada; Stewart Goldman, Ann and Robert H Lurie Children's Hospital of Chicago, Chicago, IL; Sarah Leary, Seattle Children's Hospital, University of Washington and Fred Hutchinson Cancer Research Center, Seattle, WA; Roger Packer, Children's National Health System; Javad Nazarian, Children's National Medical Center, Washington, DC; Katherine E. Warren, National Cancer Institute, Bethesda, MD; Alberto Broniscer, St Jude Children's Research Hospital, Memphis, TN; Mark W. Kieran, Dana-Farber Boston Children's Cancer and Blood Disorders Center, Boston, MA; Jane Minturn, Children's Hospital of Philadelphia and The Perelman School of Medicine at the University of Pennsylvania, Philadelphia; Melanie Comito, The Pennsylvania State University, Hershey, PA; Chie-Schin Shih, Indiana University, Indianapolis, IN; Soumen Khatua, The University of Texas MD Anderson Cancer Center; Murali Chintagumpala, Texas Children's Cancer and Hematology Centers, Baylor College of Medicine, Houston, TX; Timothy Hassall, Lady Cilento Children's Hospital, Brisbane, Queensland; David S. Ziegler, Kids Cancer Centre, Sydney Children's Hospital, Randwick; David S. Ziegler, University of New South Wales, Sydney, New South Wales; Nicholas Gottardo and Hetal Dholaria, Princess Margaret Hospital for Children, Perth, Western Australia, Australia; Martin Benesch, Medical University of Graz, Graz, Austria; Nathalie Boddaert. Stephanie Puget, and Raphaël Calmon, Hôpital Necker Enfants Malades; Pascale Varlet, Hôpital Sainte-Anne, Université Paris V Descartes, Sorbonne Paris Cité, Paris; Géraldine Giraud, David Castel, and Jacques Grill, Gustave Roussy, Université Paris-Sud, Université Paris-Saclay, Villejuif, France; Géraldine Giraud, Uppsala University, Uppsala, Sweden; Chris Jones, The Institute of Cancer Research, Sutton; Darren Hargrave, Great Ormond Street Hospital, London; Guirish A. Solanki, Birmingham Women's and Children's Hospital, Birmingham; Simon Bailey, Great North Children's Hospital, Victoria Wing, Royal Victoria Infirmary, Newcastle upon Tyne, United Kingdom; Piergiorgio Modena and Marzia Giagnacovo, Sant' Anna Como General Hospital, Como; Manila Antonelli, Sapienza University of Rome, Rome; Veronica Biassoni and Maura Massimino, Fondazione Istituto Di Ricovero e Cura a Carattere Scientifico, Istituto Nazionale dei Tumori, Milan, Italy; Nicolas U. Gerber and Michael A. Grotzer, University Children's Hospital of Zurich, Zurich; André O. von Bueren, University Hospital of Geneva and University of Geneva, Geneva, Switzerland; and Filip Jadrijevic Cvrlje and Gertjan J.L. Kaspers, Children's Hospital Zagreb, Zagreb, Croatia.

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http://dx.doi.org/10.1200/JCO.2017.75.9308DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6075859PMC
July 2018

Spectrum and prevalence of genetic predisposition in medulloblastoma: a retrospective genetic study and prospective validation in a clinical trial cohort.

Lancet Oncol 2018 06 9;19(6):785-798. Epub 2018 May 9.

Department of Pediatric Hematology and Oncology, Heidelberg University Hospital, Heidelberg, Germany; Division of Pediatric Neurooncology, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany; Hopp Children's Cancer Center at the NCT Heidelberg, Heidelberg, Germany. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S14702045183024
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http://dx.doi.org/10.1016/S1470-2045(18)30242-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5984248PMC
June 2018

Publisher Correction: Investigation of brain tissue infiltration by medulloblastoma cells in an ex vivo model.

Sci Rep 2018 Jun 21;8(1):9718. Epub 2018 Jun 21.

Children's Research Centre, Oncology, University Children's Hospital, August-Forel Strasse 1, CH-8008, Zürich, Switzerland.

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http://dx.doi.org/10.1038/s41598-018-28051-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6013467PMC
June 2018

TGF-β Determines the Pro-migratory Potential of bFGF Signaling in Medulloblastoma.

Cell Rep 2018 06;23(13):3798-3812.e8

Paediatric Neuro-Oncology Research Group, Department of Oncology, Children's Research Center, University Children's Hospital Zürich, August-Forel Strasse 1, CH-8008 Zürich, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2018.05.083DOI Listing
June 2018

Audiological monitoring in Swiss childhood cancer patients.

Pediatr Blood Cancer 2018 03 12;65(3). Epub 2017 Dec 12.

Swiss Childhood Cancer Registry, Institute of Social and Preventive Medicine, University of Bern, Bern, Switzerland.

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http://dx.doi.org/10.1002/pbc.26877DOI Listing
March 2018

Isolated intracerebral Langerhans cell histiocytosis with multifocal lesions.

Pediatr Blood Cancer 2017 11 24;64(11). Epub 2017 Apr 24.

Department of Neuropathology, University Hospital Zurich, Zurich, Switzerland.

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http://dx.doi.org/10.1002/pbc.26546DOI Listing
November 2017

Intracystic interferon-alpha in pediatric craniopharyngioma patients: an international multicenter assessment on behalf of SIOPE and ISPN.

Neuro Oncol 2017 Oct;19(10):1398-1407

Children's Brain Tumour Research Network (CBTRN), Royal Manchester Children's Hospital, Oxford Road, Manchester, England, UK; The Centre for Paediatric, Teenage and Young Adult Cancer, Institute of Cancer Sciences, The University of Manchester, England, UK; Department of Pediatric Neurosurgery, A Gemelli Hospital, Rome, Italy; Division of Pediatric Neurosurgery, Neurological Institute, Taipei Veterans General Hospital, Taipei, Taiwan; Groote Schuur Hospital, University of Cape Town, South Africa; Sophia Children's Hospital, Erasmus MC, Rotterdam, Netherlands; Department of Neurosurgery, Alder Hey Children's Hospital NHS Foundation Trust, Liverpool, England, UK ; Beatrix Childrens' Hospital, University MC, Groningen, Netherlands; Department of Neurosurgery, Medical University of Vienna, Vienna, Austria; Pediatric Haemato-Oncology Unit, University Hospital Lausanne, Switzerland; Pediatric Oncology Department, Emma Children's Hospital of the Academic Medical Center, Amsterdam, Netherlands; Department of Pediatric Neurosurgery, Karolinska University Hospital, Stockholm, Sweden; Division of Pediatric Hematology and Oncology, Department of Pediatrics and Adolescent Medicine, Medical University of Graz, Graz, Austria; Department of Pediatrics, Klinikum Oldenburg AöR, Medical Campus University Oldenburg, Oldenburg, Germany; Departments of Neurosurgery and Oncology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany; Department of Neurosurgery, University Children's Hospital Zurich, Switzerland; Departments of Paediatric Neuroendocrinology and Neurosurgery, Great Ormond Street Hospital, London, England, UK; Department of Paediatrics, Our Lady's Children's Hospital, Crumlin, Ireland; Department of Pediatric Neurosurgery, Hospital Angeles Mexico, Mexico City,Mexico; Department of Neurosurgery, Winnipeg Children's Hospital, Canada; Department of Paediatrics, Children's Hospital of Eastern Ontario, Ottawa, Canada; Department of Neurosurgery, Tel-Aviv Sourasky Medical Center, Israel; Department of Neurosurgery, National Taiwan University Hospital, Taiwan; Department of Paediatric Oncology, The Hospital for Sick Children, Toronto, Canada.

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http://dx.doi.org/10.1093/neuonc/nox056DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5596165PMC
October 2017

Investigation of brain tissue infiltration by medulloblastoma cells in an ex vivo model.

Sci Rep 2017 07 13;7(1):5297. Epub 2017 Jul 13.

Children's Research Centre, Oncology, University Children's Hospital, August-Forel Strasse 1, CH-8008, Zürich, Switzerland.

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http://dx.doi.org/10.1038/s41598-017-05573-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5509741PMC
July 2017

Ommaya reservoir "off-duty" causing major late-onset complications in a child with medulloblastoma.

Pediatr Blood Cancer 2017 06 1;64(6). Epub 2016 Dec 1.

Department of Oncology, University Children's Hospital, Zurich, Switzerland.

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http://dx.doi.org/10.1002/pbc.26384DOI Listing
June 2017

Management of primary thalamic low-grade glioma in pediatric patients: results of the multicenter treatment studies HIT-LGG 1996 and SIOP-LGG 2004.

Neurooncol Pract 2017 Mar 9;4(1):29-39. Epub 2016 Dec 9.

Department of Oncology, University Children's Hospital, Zurich, Switzerland (T.B., N.U.G., M.A.G.); Hospital for Children and Adolescents, Klinikum Augsburg, Augsburg, Germany (D.K., A.G.); Department of Pediatrics and Adolescent Medicine, Medical University of Vienna, Vienna, Austria (A.A.A.); Institute of Biostatistics and Clinical Research, University of Muenster, Germany (R.S.); Department of Neuroradiology, University of Wuerzburg, Germany (M.W.); Institute of Neuropathology, University of Bonn, Germany (T.P.); Department of Radiation Oncology, University of Leipzig, Leipzig, Germany (R.K.).

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http://dx.doi.org/10.1093/nop/npw007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6655541PMC
March 2017

Long-term auditory complications after childhood cancer: A report from the Swiss Childhood Cancer Survivor Study.

Pediatr Blood Cancer 2017 02 21;64(2):364-373. Epub 2016 Sep 21.

Swiss Childhood Cancer Registry, Institute of Social and Preventive Medicine, University of Bern, Bern, Switzerland.

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http://dx.doi.org/10.1002/pbc.26212DOI Listing
February 2017

Childhood cancer survival in Switzerland (1976-2013): Time-trends and predictors.

Int J Cancer 2017 Jan 3;140(1):62-74. Epub 2016 Oct 3.

Institute of Social and Preventive Medicine, University of Bern, Finkenhubelweg 11, CH-3012 Bern, Switzerland.

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http://dx.doi.org/10.1002/ijc.30434DOI Listing
January 2017

MYC as Therapeutic Target for Embryonal Tumors: Potential and Challenges.

Curr Cancer Drug Targets 2016 ;16(1):2-21

Department of Oncology, University Children's Hospital Zurich, Switzerland.

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http://dx.doi.org/10.2174/1568009615666150916092745DOI Listing
September 2016

Ewing's Sarcoma as a Second Malignancy in Long-Term Survivors of Childhood Hematologic Malignancies.

Sarcoma 2016 25;2016:5043640. Epub 2016 Jul 25.

Institute of Surgical Pathology, University Hospital Zurich, Schmelzbergstrasse 12, 8091 Zurich, Switzerland.

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http://dx.doi.org/10.1155/2016/5043640DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4976151PMC
August 2016

Therapeutic Impact of Cytoreductive Surgery and Irradiation of Posterior Fossa Ependymoma in the Molecular Era: A Retrospective Multicohort Analysis.

Authors:
Vijay Ramaswamy Thomas Hielscher Stephen C Mack Alvaro Lassaletta Tong Lin Kristian W Pajtler David T W Jones Betty Luu Florence M G Cavalli Kenneth Aldape Marc Remke Martin Mynarek Stefan Rutkowski Sridharan Gururangan Roger E McLendon Eric S Lipp Christopher Dunham Juliette Hukin David D Eisenstat Dorcas Fulton Frank K H van Landeghem Mariarita Santi Marie-Lise C van Veelen Erwin G Van Meir Satoru Osuka Xing Fan Karin M Muraszko Daniela P C Tirapelli Sueli M Oba-Shinjo Suely K N Marie Carlos G Carlotti Ji Yeoun Lee Amulya A Nageswara Rao Caterina Giannini Claudia C Faria Sofia Nunes Jaume Mora Ronald L Hamilton Peter Hauser Nada Jabado Kevin Petrecca Shin Jung Luca Massimi Massimo Zollo Giuseppe Cinalli László Bognár Almos Klekner Tibor Hortobágyi Sarah Leary Ralph P Ermoian James M Olson Jeffrey R Leonard Corrine Gardner Wieslawa A Grajkowska Lola B Chambless Jason Cain Charles G Eberhart Sama Ahsan Maura Massimino Felice Giangaspero Francesca R Buttarelli Roger J Packer Lyndsey Emery William H Yong Horacio Soto Linda M Liau Richard Everson Andrew Grossbach Tarek Shalaby Michael Grotzer Matthias A Karajannis David Zagzag Helen Wheeler Katja von Hoff Marta M Alonso Teresa Tuñon Ulrich Schüller Karel Zitterbart Jaroslav Sterba Jennifer A Chan Miguel Guzman Samer K Elbabaa Howard Colman Girish Dhall Paul G Fisher Maryam Fouladi Amar Gajjar Stewart Goldman Eugene Hwang Marcel Kool Harshad Ladha Elizabeth Vera-Bolanos Khalida Wani Frank Lieberman Tom Mikkelsen Antonio M Omuro Ian F Pollack Michael Prados H Ian Robins Riccardo Soffietti Jing Wu Phillipe Metellus Uri Tabori Ute Bartels Eric Bouffet Cynthia E Hawkins James T Rutka Peter Dirks Stefan M Pfister Thomas E Merchant Mark R Gilbert Terri S Armstrong Andrey Korshunov David W Ellison Michael D Taylor

J Clin Oncol 2016 07 6;34(21):2468-77. Epub 2016 Jun 6.

Vijay Ramaswamy, Stephen C. Mack, Alvaro Lassaletta, Betty Luu, Florence M.G. Cavalli, Uri Tabori, Ute Bartels, Eric Bouffet, Cynthia E. Hawkins, James T. Rutka, Peter Dirks, and Michael D. Taylor, The Hospital for Sick Children; Vijay Ramaswamy, Kenneth Aldape, James T. Rutka, and Michael D. Taylor, University of Toronto; Kenneth Aldape, Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario; Christopher Dunham and Juliette Hukin, British Columbia Children's Hospital; Juliette Hukin, University of British Columbia, Vancouver, British Columbia; David D. Eisenstat, Dorcas Fulton, and Frank K.H. van Landeghem, University of Alberta, Edmonton; Jennifer A. Chan, University of Calgary, Calgary, Alberta; Nada Jabado and Kevin Petrecca, McGill University, Montreal, Quebec, Canada; Thomas Hielscher, Kristian W. Pajtler, David T.W. Jones, Marcel Kool, Stefan M. Pfister, and Andrey Korshunov, German Cancer Research Center; Stefan M. Pfister, University Hospital Heidelberg, Heidelberg; Marc Remke, University Hospital Düsseldorf, Düsseldorf; Martin Mynarek, Stefan Rutkowski, and Katja von Hoff, University Medical Center Hamburg-Eppendorf, Hamburg; Ulrich Schüller, Ludwig-Maximilians-Universität, Munich, Germany; Stephen C. Mack, Cleveland Clinic Foundation, Cleveland; Maryam Fouladi, University of Cincinnati, Cincinnati Children's Hospital Medical Center, Cincinnati, OH; Tong Lin, Amar Gajjar, Thomas E. Merchant, and David W. Ellison, St Jude Children's Research Hospital, Memphis; Lola B. Chambless, Vanderbilt Medical Center, Nashville, TN; Sridharan Gururangan, Roger E. McLendon, and Eric S. Lipp, Duke University, Durham; Jing Wu, University of North Carolina at Chapel Hill, Chapel Hill, NC; Mariarita Santi, Children's Hospital of Philadelphia; Lyndsey Emery, Hospital of the University of Pennsylvania, Philadelphia; Ronald L. Hamilton and Ian F. Pollack, University of Pittsburgh School of Medicine; Frank Lieberman, University of Pittsburgh Medical Cen

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http://dx.doi.org/10.1200/JCO.2015.65.7825DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4962737PMC
July 2016

Socioeconomic disparities in childhood cancer survival in Switzerland.

Int J Cancer 2016 Jun 1;138(12):2856-66. Epub 2016 Mar 1.

Institute of Social and Preventive Medicine, University of Bern, 3012, Bern, Switzerland.

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http://dx.doi.org/10.1002/ijc.30029DOI Listing
June 2016

Space-time clustering of childhood cancers in Switzerland: A nationwide study.

Int J Cancer 2016 May 8;138(9):2127-35. Epub 2016 Jan 8.

Institute of Social and Preventive Medicine (ISPM), University of Bern, Bern, Switzerland.

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http://dx.doi.org/10.1002/ijc.29955DOI Listing
May 2016

Pencil beam scanning proton therapy for pediatric intracranial ependymoma.

J Neurooncol 2016 05 5;128(1):137-145. Epub 2016 Mar 5.

Center for Proton Therapy, Paul Scherrer Institute, Villigen PSI, Switzerland.

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http://dx.doi.org/10.1007/s11060-016-2090-4DOI Listing
May 2016

The Changing Landscape of Pediatric Low-Grade Gliomas: Clinical Challenges and Emerging Therapies.

Neuropediatrics 2016 Apr 14;47(2):70-83. Epub 2016 Jan 14.

Division of Oncology, University Children's Hospital of Zurich, Zurich, Switzerland.

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http://dx.doi.org/10.1055/s-0035-1570491DOI Listing
April 2016

Prognostic value of medulloblastoma extent of resection after accounting for molecular subgroup: a retrospective integrated clinical and molecular analysis.

Authors:
Eric M Thompson Thomas Hielscher Eric Bouffet Marc Remke Betty Luu Sridharan Gururangan Roger E McLendon Darell D Bigner Eric S Lipp Sebastien Perreault Yoon-Jae Cho Gerald Grant Seung-Ki Kim Ji Yeoun Lee Amulya A Nageswara Rao Caterina Giannini Kay Ka Wai Li Ho-Keung Ng Yu Yao Toshihiro Kumabe Teiji Tominaga Wieslawa A Grajkowska Marta Perek-Polnik David C Y Low Wan Tew Seow Kenneth T E Chang Jaume Mora Ian F Pollack Ronald L Hamilton Sarah Leary Andrew S Moore Wendy J Ingram Andrew R Hallahan Anne Jouvet Michelle Fèvre-Montange Alexandre Vasiljevic Cecile Faure-Conter Tomoko Shofuda Naoki Kagawa Naoya Hashimoto Nada Jabado Alexander G Weil Tenzin Gayden Takafumi Wataya Tarek Shalaby Michael Grotzer Karel Zitterbart Jaroslav Sterba Leos Kren Tibor Hortobágyi Almos Klekner Bognár László Tímea Pócza Peter Hauser Ulrich Schüller Shin Jung Woo-Youl Jang Pim J French Johan M Kros Marie-Lise C van Veelen Luca Massimi Jeffrey R Leonard Joshua B Rubin Rajeev Vibhakar Lola B Chambless Michael K Cooper Reid C Thompson Claudia C Faria Alice Carvalho Sofia Nunes José Pimentel Xing Fan Karin M Muraszko Enrique López-Aguilar David Lyden Livia Garzia David J H Shih Noriyuki Kijima Christian Schneider Jennifer Adamski Paul A Northcott Marcel Kool David T W Jones Jennifer A Chan Ana Nikolic Maria Luisa Garre Erwin G Van Meir Satoru Osuka Jeffrey J Olson Arman Jahangiri Brandyn A Castro Nalin Gupta William A Weiss Iska Moxon-Emre Donald J Mabbott Alvaro Lassaletta Cynthia E Hawkins Uri Tabori James Drake Abhaya Kulkarni Peter Dirks James T Rutka Andrey Korshunov Stefan M Pfister Roger J Packer Vijay Ramaswamy Michael D Taylor

Lancet Oncol 2016 04 12;17(4):484-495. Epub 2016 Mar 12.

Division of Neurosurgery, The Hospital for Sick Children, Toronto, ON, Canada; The Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, Toronto, ON, Canada; Developmental & Stem Cell Biology Program, The Hospital for Sick Children, Toronto, ON, Canada; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S14702045150058
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http://dx.doi.org/10.1016/S1470-2045(15)00581-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4907853PMC
April 2016

New Brain Tumor Entities Emerge from Molecular Classification of CNS-PNETs.

Authors:
Dominik Sturm Brent A Orr Umut H Toprak Volker Hovestadt David T W Jones David Capper Martin Sill Ivo Buchhalter Paul A Northcott Irina Leis Marina Ryzhova Christian Koelsche Elke Pfaff Sariah J Allen Gnanaprakash Balasubramanian Barbara C Worst Kristian W Pajtler Sebastian Brabetz Pascal D Johann Felix Sahm Jüri Reimand Alan Mackay Diana M Carvalho Marc Remke Joanna J Phillips Arie Perry Cynthia Cowdrey Rachid Drissi Maryam Fouladi Felice Giangaspero Maria Łastowska Wiesława Grajkowska Wolfram Scheurlen Torsten Pietsch Christian Hagel Johannes Gojo Daniela Lötsch Walter Berger Irene Slavc Christine Haberler Anne Jouvet Stefan Holm Silvia Hofer Marco Prinz Catherine Keohane Iris Fried Christian Mawrin David Scheie Bret C Mobley Matthew J Schniederjan Mariarita Santi Anna M Buccoliero Sonika Dahiya Christof M Kramm André O von Bueren Katja von Hoff Stefan Rutkowski Christel Herold-Mende Michael C Frühwald Till Milde Martin Hasselblatt Pieter Wesseling Jochen Rößler Ulrich Schüller Martin Ebinger Jens Schittenhelm Stephan Frank Rainer Grobholz Istvan Vajtai Volkmar Hans Reinhard Schneppenheim Karel Zitterbart V Peter Collins Eleonora Aronica Pascale Varlet Stephanie Puget Christelle Dufour Jacques Grill Dominique Figarella-Branger Marietta Wolter Martin U Schuhmann Tarek Shalaby Michael Grotzer Timothy van Meter Camelia-Maria Monoranu Jörg Felsberg Guido Reifenberger Matija Snuderl Lynn Ann Forrester Jan Koster Rogier Versteeg Richard Volckmann Peter van Sluis Stephan Wolf Tom Mikkelsen Amar Gajjar Kenneth Aldape Andrew S Moore Michael D Taylor Chris Jones Nada Jabado Matthias A Karajannis Roland Eils Matthias Schlesner Peter Lichter Andreas von Deimling Stefan M Pfister David W Ellison Andrey Korshunov Marcel Kool

Cell 2016 Feb;164(5):1060-1072

Division of Pediatric Neurooncology, German Cancer Research Center (DKFZ) and German Cancer Consortium (DKTK), 69120 Heidelberg, Germany.

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http://www.cell.com/cell/pdf/S0092-8674(16)00055-6.pdf
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http://www.cell.com/cms/attachment/2048488015/2058390163/mmc
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http://linkinghub.elsevier.com/retrieve/pii/S009286741600055
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http://dx.doi.org/10.1016/j.cell.2016.01.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5139621PMC
February 2016

Colostomy for Perianal Sepsis With Ecthyma Gangrenosum in Immunocompromised Children.

J Pediatr Hematol Oncol 2016 Jan;38(1):53-7

*Department of Pediatric Surgery ‡Division of Infectious Diseases and Hospital Epidemiology §Division of Oncology †Children's Research Centre, University Children's Hospital of Zurich, Zurich, Switzerland.

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http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
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http://dx.doi.org/10.1097/MPH.0000000000000324DOI Listing
January 2016

Divergent clonal selection dominates medulloblastoma at recurrence.

Authors:
A Sorana Morrissy Livia Garzia David J H Shih Scott Zuyderduyn Xi Huang Patryk Skowron Marc Remke Florence M G Cavalli Vijay Ramaswamy Patricia E Lindsay Salomeh Jelveh Laura K Donovan Xin Wang Betty Luu Kory Zayne Yisu Li Chelsea Mayoh Nina Thiessen Eloi Mercier Karen L Mungall Yusanne Ma Kane Tse Thomas Zeng Karey Shumansky Andrew J L Roth Sohrab Shah Hamza Farooq Noriyuki Kijima Borja L Holgado John J Y Lee Stuart Matan-Lithwick Jessica Liu Stephen C Mack Alex Manno K A Michealraj Carolina Nor John Peacock Lei Qin Juri Reimand Adi Rolider Yuan Y Thompson Xiaochong Wu Trevor Pugh Adrian Ally Mikhail Bilenky Yaron S N Butterfield Rebecca Carlsen Young Cheng Eric Chuah Richard D Corbett Noreen Dhalla An He Darlene Lee Haiyan I Li William Long Michael Mayo Patrick Plettner Jenny Q Qian Jacqueline E Schein Angela Tam Tina Wong Inanc Birol Yongjun Zhao Claudia C Faria José Pimentel Sofia Nunes Tarek Shalaby Michael Grotzer Ian F Pollack Ronald L Hamilton Xiao-Nan Li Anne E Bendel Daniel W Fults Andrew W Walter Toshihiro Kumabe Teiji Tominaga V Peter Collins Yoon-Jae Cho Caitlin Hoffman David Lyden Jeffrey H Wisoff James H Garvin Duncan S Stearns Luca Massimi Ulrich Schüller Jaroslav Sterba Karel Zitterbart Stephanie Puget Olivier Ayrault Sandra E Dunn Daniela P C Tirapelli Carlos G Carlotti Helen Wheeler Andrew R Hallahan Wendy Ingram Tobey J MacDonald Jeffrey J Olson Erwin G Van Meir Ji-Yeoun Lee Kyu-Chang Wang Seung-Ki Kim Byung-Kyu Cho Torsten Pietsch Gudrun Fleischhack Stephan Tippelt Young Shin Ra Simon Bailey Janet C Lindsey Steven C Clifford Charles G Eberhart Michael K Cooper Roger J Packer Maura Massimino Maria Luisa Garre Ute Bartels Uri Tabori Cynthia E Hawkins Peter Dirks Eric Bouffet James T Rutka Robert J Wechsler-Reya William A Weiss Lara S Collier Adam J Dupuy Andrey Korshunov David T W Jones Marcel Kool Paul A Northcott Stefan M Pfister David A Largaespada Andrew J Mungall Richard A Moore Nada Jabado Gary D Bader Steven J M Jones David Malkin Marco A Marra Michael D Taylor

Nature 2016 Jan 13;529(7586):351-7. Epub 2016 Jan 13.

Developmental &Stem Cell Biology Program, The Hospital for Sick Children, Toronto, Ontario M5G 0A4, Canada.

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http://dx.doi.org/10.1038/nature16478DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4936195PMC
January 2016

Ventricular Catheter Systems with Subcutaneous Reservoirs (Ommaya Reservoirs) in Pediatric Patients with Brain Tumors: Infections and Other Complications.

Neuropediatrics 2015 Dec 19;46(6):401-9. Epub 2015 Oct 19.

Department of Oncology, University Children's Hospital of Zurich, Zurich, Switzerland.

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http://dx.doi.org/10.1055/s-0035-1565271DOI Listing
December 2015

Tumor-Associated CSF MicroRNAs for the Prediction and Evaluation of CNS Malignancies.

Int J Mol Sci 2015 Dec 7;16(12):29103-19. Epub 2015 Dec 7.

Department of Oncology, University Children's Hospital, CH-8032 Zurich, Switzerland.

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http://dx.doi.org/10.3390/ijms161226150DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4691097PMC
December 2015

Computer-assisted quantification of motile and invasive capabilities of cancer cells.

Sci Rep 2015 Oct 21;5:15338. Epub 2015 Oct 21.

Department of Oncology, Children's Research Center, University Children's Hospital Zürich, August-Forel Strasse 1, CH-8008 Zürich, Switzerland.

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http://dx.doi.org/10.1038/srep15338DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4614254PMC
October 2015

Contrast-enhanced MRI of the temporomandibular joint: findings in children without juvenile idiopathic arthritis.

Acta Radiol 2015 Sep 12;56(9):1145-52. Epub 2014 Sep 12.

Department of Diagnostic Imaging, University Children's Hospital Zürich, Switzerland

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September 2015

Intraoperative Monitoring of Facial Nerve Motor-Evoked Potentials in Children.

World Neurosurg 2015 Sep 16;84(3):786-94. Epub 2015 May 16.

Neurosurgery Department, University Hospital Zurich, Zurich, Switzerland; University of Zurich, Zurich, Switzerland; Zurich Neuroscience Center, ETHZ, Zurich, Switzerland. Electronic address:

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September 2015

CCDC26, CDKN2BAS, RTEL1 and TERT Polymorphisms in pediatric brain tumor susceptibility.

Carcinogenesis 2015 Aug 25;36(8):876-82. Epub 2015 May 25.

Unit of Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Box 210, Stockholm SE-171 77, Sweden, Neurogenetics Unit, Department of Molecular Medicine and Surgery, Karolinska Institutet, and Center for Molecular Medicine, Karolinska University Hospital, Stockholm SE-171 76, Sweden, Section of Environment and Radiation, International Agency for Research on Cancer (IARC), 69372 Lyon CEDEX 08, France, Department of Epidemiology and Public Health, Swiss Tropical and Public Health Institute, Basel 4002, Switzerland, University of Basel, Basel 4003, Switzerland, The Cancer Registry of Norway, Oslo N-0304, Norway, National Institute of Occupational Health, Oslo NO-0033, Norway, Department of Oncology, University Children's Hospital of Zurich, Zurich 8091, Switzerland, Unit of Survivorship, The Danish Cancer Society Research Centre, Copenhagen DK-2100, Denmark, 5073 Oncology Clinic, Finsen Centre Rigshospitalet, University of Copenhagen, Copenhagen DK-2100, Denmark, Swiss Childhood Cancer Registry, Institute of Social and Preventive Medicine, University of Bern, Bern 3012, Switzerland, Department of Clinical Sciences, Pediatric Oncology, University of Gothenburg, SE 416 85 Gothenburg, Sweden and Department of Pediatric Oncology, University Hospital Rigshospitalet, Copenhagen DK-2100, Denmark.

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http://dx.doi.org/10.1093/carcin/bgv074DOI Listing
August 2015

Image-based RNA interference screening reveals an individual dependence of acute lymphoblastic leukemia on stromal cysteine support.

Oncotarget 2014 Nov;5(22):11501-12

Department of Pediatric Oncology, University Children's Hospital Zurich, Zurich, Switzerland. Children's Research Center (CRC), University Children's Hospital Zurich, Zurich, Switzerland.

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http://dx.doi.org/10.18632/oncotarget.2572DOI Listing
November 2014

MicroRNA signatures as biomarkers and therapeutic target for CNS embryonal tumors: the pros and the cons.

Int J Mol Sci 2014 Nov 24;15(11):21554-86. Epub 2014 Nov 24.

Department of Oncology, University Children's Hospital of Zurich, Steinwiesstrasse 75, Zurich 8032, Switzerland.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4264241PMC
November 2014

Sellar and parasellar lesions - clinical outcome in 61 children.

Clin Neurol Neurosurg 2014 Aug 6;123:102-8. Epub 2014 May 6.

Department of Neurosurgery, University Hospital Zurich, Zurich, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.clineuro.2014.04.026DOI Listing
August 2014

Significance and therapeutic value of miRNAs in embryonal neural tumors.

Molecules 2014 May 6;19(5):5821-62. Epub 2014 May 6.

Department of Oncology, University Children's Hospital of Zurich, Zurich 8008, Switzerland.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271640PMC
May 2014

NOTCH ligands JAG1 and JAG2 as critical pro-survival factors in childhood medulloblastoma.

Acta Neuropathol Commun 2014 Apr 7;2:39. Epub 2014 Apr 7.

Department of Oncology, University Children's Hospital of Zurich, Zurich, Switzerland.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4023630PMC
April 2014

Clinical reasoning: a 30-year-old woman with recurrent seizures and a cerebral lesion progressing over 2 decades.

Neurology 2014 Feb;82(7):e56-60

From the Departments of Neurology (M.T., M.W., P.R.), Neurosurgery (O.S.), Neuroradiology (A.V.), and Nuclear Medicine (A.B.), and Institute of Neuropathology (E.J.R.), University Hospital Zurich; and the Department of Oncology (M.G.), University Children's Hospital of Zurich, Switzerland.

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February 2014

Apparent diffusion coefficient of pediatric cerebellar tumors: a biomarker of tumor grade?

Pediatr Blood Cancer 2013 Dec 12;60(12):2036-41. Epub 2013 Aug 12.

Division of Pediatric Radiology, Russell H. Morgan Department of Radiology and Radiological Science, The Johns Hopkins University School of Medicine, Baltimore, MD; Division of Pediatric Neurology, University Children's Hospital, Zurich, Switzerland.

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December 2013

G-quadruplexes as potential therapeutic targets for embryonal tumors.

Molecules 2013 Oct 10;18(10):12500-37. Epub 2013 Oct 10.

Division of Oncology, University Children's Hospital of Zurich, Zurich 8032, Switzerland.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269990PMC
October 2013

Anaplastic ganglioglioma: a very rare intramedullary spinal cord tumor.

Pediatr Neurosurg 2012 21;48(1):42-7. Epub 2012 Aug 21.

Division of Neurosurgery, Cantonal Hospital of Lucerne, Lucerne, Switzerland.

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August 2013

Isolated intraspinal juvenile xanthogranuloma in an infant presenting as acute paraplegia.

Neuropediatrics 2013 Jun 19;44(3):171-3. Epub 2012 Dec 19.

Department of Neuropediatrics, University Children's Hospital Zurich, Zurich, Switzerland.

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http://dx.doi.org/10.1055/s-0032-1329908DOI Listing
June 2013

Pediatric papillary tumors of the pineal region: to observe or to treat following gross total resection?

Childs Nerv Syst 2013 Feb 6;29(2):307-10. Epub 2012 Oct 6.

Department of Oncology, University Children's Hospital of Zurich, Zurich, Switzerland.

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http://dx.doi.org/10.1007/s00381-012-1935-1DOI Listing
February 2013

Surgical resection of pediatric skull base meningiomas.

Childs Nerv Syst 2013 Jan 13;29(1):83-7. Epub 2012 Sep 13.

Department of Neurosurgery, University Hospital of Zurich, Frauenklinikstrasse 10, Zurich 8091, Switzerland.

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http://dx.doi.org/10.1007/s00381-012-1906-6DOI Listing
January 2013

Treatment of children with brain tumors in developing countries.

Neuropediatrics 2012 Oct 12;43(5):231. Epub 2012 Oct 12.

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October 2012

Neuroblastoma with spinal cord compression: is there an emergency treatment of choice?

Dev Med Child Neurol 2012 Apr 13;54(4):297-8. Epub 2012 Feb 13.

The Russell H Morgan Department of Radiology and Radiological Science, The Johns Hopkins School of Medicine, Baltimore, MD, USA.

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http://dx.doi.org/10.1111/j.1469-8749.2011.04174.xDOI Listing
April 2012

Genetic alterations in microRNAs in medulloblastomas.

Brain Pathol 2012 Mar 15;22(2):230-9. Epub 2011 Sep 15.

International Agency for Research on Cancer (IARC), Lyon, France Neuro-Oncology Program, University Children's Hospital of Zurich, Switzerland.

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March 2012

Educational achievement in Swiss childhood cancer survivors compared with the general population.

Cancer 2012 Mar 5;118(5):1439-49. Epub 2011 Aug 5.

Swiss Childhood Cancer Registry, Institute of Social and Preventive Medicine, University of Bern, Bern, Switzerland.

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http://doi.wiley.com/10.1002/cncr.26418
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March 2012

Incidental findings of mass lesions on neuroimages in children.

Neurosurg Focus 2011 Dec;31(6):E20

Department of Oncology, University Children’s Hospital of Zurich, Zurich, Switzerland.

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http://dx.doi.org/10.3171/2011.9.FOCUS11121DOI Listing
December 2011

MicroRNA-21 suppression impedes medulloblastoma cell migration.

Eur J Cancer 2011 Nov 19;47(16):2479-90. Epub 2011 Jul 19.

Oncology Department, University Children's Hospital of Zurich, Switzerland.

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http://dx.doi.org/10.1016/j.ejca.2011.06.041DOI Listing
November 2011

Mobile phone use and brain tumors in children and adolescents: a multicenter case-control study.

J Natl Cancer Inst 2011 Aug 27;103(16):1264-76. Epub 2011 Jul 27.

Department of Epidemiology and Public Health, Swiss Tropical and Public Health Institute, Socinstrasse 57, P.O. Box, 4002 Basel, Switzerland.

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http://dx.doi.org/10.1093/jnci/djr244DOI Listing
August 2011

Expression of O⁶-methylguanine-DNA methyltransferase in childhood medulloblastoma.

J Neurooncol 2011 May 5;103(1):59-69. Epub 2010 Sep 5.

Neuro-Oncology Program, University Children's Hospital, Steinwiesstrasse 75, 8032 Zurich, Switzerland.

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http://dx.doi.org/10.1007/s11060-010-0366-7DOI Listing
May 2011

Does diagnostic delay result in decreased survival in paediatric brain tumours?

Eur J Pediatr 2009 Mar 7;168(3):303-10. Epub 2008 Jun 7.

Department of Oncology, University Children's Hospital of Zurich, Steinwiesstrasse 75, 8032, Zurich, Switzerland.

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http://link.springer.com/10.1007/s00431-008-0755-5
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March 2009

Targeting Myc in pediatric malignancies of the central and peripheral nervous system.

Curr Cancer Drug Targets 2009 Mar;9(2):176-88

Department of Oncology, University Children's Hospital Zurich, Steinwiesstrasse 75, Zurich, Switzerland.

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http://dx.doi.org/10.2174/156800909787580962DOI Listing
March 2009

Magnetic toys: forbidden for pediatric patients with certain programmable shunt valves?

Childs Nerv Syst 2009 Feb 5;25(2):161-4. Epub 2008 Dec 5.

Division of Oncology, University Children's Hospital of Zurich, Steinwiesstrasse 75, 8032, Zurich, Switzerland.

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February 2009

Neurotrophin 3/TrkC-regulated proteins in the human medulloblastoma cell line DAOY.

Electrophoresis 2009 Feb;30(3):540-9

Department of Pediatrics, Medical University of Vienna, Vienna, Austria.

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http://doi.wiley.com/10.1002/elps.200800325
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February 2009

Outcome of children with low-grade cerebellar astrocytoma: long-term complications and quality of life.

Childs Nerv Syst 2008 Dec 9;24(12):1447-55. Epub 2008 Aug 9.

Division of Oncology, University Children's Hospital of Zurich, Steinwiesstrasse 75, 8032, Zurich, Switzerland.

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December 2008

Temperature sensitivity of phospho-Ser(473)-PKB/AKT.

Biochem Biophys Res Commun 2008 Oct 20;375(3):399-404. Epub 2008 Aug 20.

Department of Radiation Oncology, University Hospital Zurich, CH-8091 Zurich, Switzerland.

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http://dx.doi.org/10.1016/j.bbrc.2008.08.035DOI Listing
October 2008

A psychoeducational intervention reduces the need for anesthesia during radiotherapy for young childhood cancer patients.

Radiat Oncol 2008 Jun 4;3:17. Epub 2008 Jun 4.

University Children's Hospital of Zurich, Department of Oncology, Steinwiesstr, 75, 8032 Zurich, Switzerland.

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http://dx.doi.org/10.1186/1748-717X-3-17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2430970PMC
June 2008

Conservative management of acute appendicitis in children with hematologic malignancies during chemotherapy-induced neutropenia.

J Pediatr Hematol Oncol 2008 Jun;30(6):464-7

Department of Pediatric Oncology, University Children's Hospital, University of Zurich, Zurich, Switzerland.

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http://dx.doi.org/10.1097/MPH.0b013e318168e7cbDOI Listing
June 2008

Synthesis, chaperoning, and metabolism of proteins are regulated by NT-3/TrkC signaling in the medulloblastoma cell line DAOY.

J Proteome Res 2008 May 13;7(5):1932-44. Epub 2008 Mar 13.

Department of Pediatrics, Medical University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.1021/pr700724aDOI Listing
May 2008

Long-term complications and quality of life in children with intraspinal tumors.

Pediatr Blood Cancer 2008 Apr;50(4):844-8

Division of Neurology, University Children's Hospital of Zurich, Zurich, Switzerland.

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http://dx.doi.org/10.1002/pbc.21284DOI Listing
April 2008

Targeting the phosphoinositide 3-kinase isoform p110delta impairs growth and survival in neuroblastoma cells.

Clin Cancer Res 2008 Feb;14(4):1172-81

Division of Clinical Chemistry and Biochemistry, University Children's Hospital Zurich, Zurich, Switzerland.

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http://dx.doi.org/10.1158/1078-0432.CCR-07-0737DOI Listing
February 2008

IGF signaling as a therapeutic target in pediatric solid tumors of the central and peripheral nervous system.

Expert Rev Endocrinol Metab 2007 Sep;2(5):677-688

b University Children's Hospital of Zurich, Division of Clinical Chemistry and Biochemistry, Zurich, Switzerland.

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September 2007