Publications by authors named "Michael Groessl"

54Publications

Rapid quantification of insulin degludec by immunopurification combined with liquid chromatography high-resolution mass spectrometry.

Anal Bioanal Chem 2020 Oct 2. Epub 2020 Oct 2.

Department of Diabetes, Endocrinology, Nutritional Medicine and Metabolism, Inselspital, Bern University Hospital, University of Bern, 3010, Bern, Switzerland.

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http://dx.doi.org/10.1007/s00216-020-02971-4DOI Listing
October 2020

Premature Adrenarche in Girls Characterized By Enhanced 17,20-Lyase and 17β-Hydroxysteroid Dehydrogenase Activities.

J Clin Endocrinol Metab 2020 Dec;105(12)

Pediatric Endocrinology, Diabetology and Metabolism, Department of Pediatrics, Bern University Hospital, University of Bern, Bern, Switzerland.

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http://dx.doi.org/10.1210/clinem/dgaa598DOI Listing
December 2020

Urinary steroid profiles: comparison of spot and 24-hour collections.

J Steroid Biochem Mol Biol 2020 Jun 21;200:105662. Epub 2020 Mar 21.

Department of Nephrology and Hypertension and Department of BioMedical Research, Inselspital, Bern University Hospital, University of Bern, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.jsbmb.2020.105662DOI Listing
June 2020

Concentration and Chemical Stability of Commercially Available Insulins: A High-Resolution Mass Spectrometry Study.

Diabetes Technol Ther 2020 04 7;22(4):326-329. Epub 2020 Feb 7.

Department of Nephrology and Hypertension, Inselspital, Bern University Hospital and University of Bern, Bern, Switzerland.

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http://dx.doi.org/10.1089/dia.2019.0412DOI Listing
April 2020

Steroid identification via deep learning retention time predictions and two-dimensional gas chromatography-high resolution mass spectrometry.

J Chromatogr A 2020 Feb 28;1612:460661. Epub 2019 Oct 28.

Department of Nephrology and Hypertension and Department of BioMedical Research, Inselspital, Bern University Hospital, University of Bern, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.chroma.2019.460661DOI Listing
February 2020

Quantitative Fragmentation Model for Bottom-Up Shotgun Lipidomics.

Anal Chem 2019 09 5;91(18):12085-12093. Epub 2019 Sep 5.

Max Planck Institute of Molecular Cell Biology and Genetics , Pfotenhauerstr. 108 , 01307 Dresden , Germany.

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http://dx.doi.org/10.1021/acs.analchem.9b03270DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6751524PMC
September 2019

How high-resolution techniques enable reliable steroid identification and quantification.

J Steroid Biochem Mol Biol 2019 02 27;186:74-78. Epub 2018 Sep 27.

Department of Nephrology and Hypertension and Department of BioMedical Research, Inselspital, Bern University Hospital, University of Bern, Switzerland. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S09600760183059
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http://dx.doi.org/10.1016/j.jsbmb.2018.09.018DOI Listing
February 2019

A comprehensive urinary steroid analysis strategy using two-dimensional gas chromatography - time of flight mass spectrometry.

Analyst 2018 Sep;143(18):4484-4494

Department of Nephrology and Hypertension and Department of BioMedical Research, Inselspital, Bern University Hospital, University of Bern, Switzerland.

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http://dx.doi.org/10.1039/c7an01990dDOI Listing
September 2018

A calibration framework for the determination of accurate collision cross sections of polyanions using polyoxometalate standards.

Rapid Commun Mass Spectrom 2018 Oct;32(19):1703-1710

Normandie Univ, UNIROUEN, INSA Rouen, CNRS, COBRA, 76000, Rouen, France.

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http://dx.doi.org/10.1002/rcm.8230DOI Listing
October 2018

High-Resolution Ion Mobility Spectrometry for Rapid Cannabis Potency Testing.

Anal Chem 2018 08 10;90(15):8764-8768. Epub 2018 Jul 10.

Department of Nephrology and Hypertension and Department of BioMedical Research, Inselspital, Bern University Hospital , University of Bern , 3010 Bern , Switzerland.

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http://dx.doi.org/10.1021/acs.analchem.8b02180DOI Listing
August 2018

Simultaneous endo and exo Complex Formation of Pyridine[4]arene Dimers with Neutral and Anionic Guests.

Angew Chem Int Ed Engl 2017 08 4;56(36):10942-10946. Epub 2017 Aug 4.

University of Jyväskylä, Department of Chemistry, Nanoscience Center, P.O. Box 35, 40014, Jyväskylä, Finland.

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http://dx.doi.org/10.1002/anie.201704054DOI Listing
August 2017

Highly Oxygenated Multifunctional Compounds in α-Pinene Secondary Organic Aerosol.

Environ Sci Technol 2017 Jun 10;51(11):5932-5940. Epub 2017 May 10.

Center for Aerosol and Cloud Chemistry, Aerodyne Research Inc. , Billerica, Massachusetts 01821, United States.

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http://dx.doi.org/10.1021/acs.est.6b06588DOI Listing
June 2017

Response Profiling Using Shotgun Proteomics Enables Global Metallodrug Mechanisms of Action To Be Established.

Chemistry 2017 Feb 10;23(8):1881-1890. Epub 2017 Jan 10.

Department of Analytical Chemistry, Faculty of Chemistry, University of Vienna, Waehringer Strasse 38, 1090, Vienna, Austria.

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http://dx.doi.org/10.1002/chem.201604516DOI Listing
February 2017

Superchiral Pd3 L6 Coordination Complex and Its Reversible Structural Conversion into Pd3 L3 Cl6 Metallocycles.

Angew Chem Int Ed Engl 2015 Dec 4;54(51):15462-7. Epub 2015 Nov 4.

University of Jyvaskyla, Department of Chemistry, Nanoscience Center, P.O. Box 35, 40014 University of Jyvaskyla (Finland).

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http://dx.doi.org/10.1002/anie.201506539DOI Listing
December 2015

DOSY NMR, X-ray Structural and Ion-Mobility Mass Spectrometric Studies on Electron-Deficient and Electron-Rich M6L4 Coordination Cages.

Inorg Chem 2015 Jun 3;54(12):6055-61. Epub 2015 Jun 3.

†University of Jyväskylä, Department of Chemistry, Nanoscience Center, P.O. Box 35, FI-40014, University of Jyväskylä, Finland.

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http://dx.doi.org/10.1021/acs.inorgchem.5b01082DOI Listing
June 2015

Proteome profiling of breast cancer biopsies reveals a wound healing signature of cancer-associated fibroblasts.

J Proteome Res 2014 Nov 3;13(11):4773-82. Epub 2014 Oct 3.

Department of Analytical Chemistry, Faculty of Chemistry, University of Vienna , Währingerstr. 38, Vienna A-1090, Austria.

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http://dx.doi.org/10.1021/pr500727hDOI Listing
November 2014

Ligand substitutions between ruthenium-cymene compounds can control protein versus DNA targeting and anticancer activity.

Nat Commun 2014 Mar 18;5:3462. Epub 2014 Mar 18.

Division of Structural Biology and Biochemistry, School of Biological Sciences, Nanyang Technological University, 60 Nanyang Drive, Singapore 637551, Singapore.

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http://dx.doi.org/10.1038/ncomms4462DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3959212PMC
March 2014

Changes of several brain receptor complexes in the cerebral cortex of patients with Alzheimer disease: probable new potential pharmaceutical targets.

Amino Acids 2014 Jan 29;46(1):223-33. Epub 2013 Nov 29.

Department of Pediatrics, Medical University of Vienna, Währinger Gürtel 18-20, 1090, Vienna, Austria.

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http://link.springer.com/10.1007/s00726-013-1623-9
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http://dx.doi.org/10.1007/s00726-013-1623-9DOI Listing
January 2014

Application of mass spectrometric techniques to delineate the modes-of-action of anticancer metallodrugs.

Chem Soc Rev 2013 Jul;42(14):6186-99

School of Chemical Sciences, The University of Auckland, 1142 Auckland, New Zealand.

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http://dx.doi.org/10.1039/c3cs35532bDOI Listing
July 2013

Synthesis and characterization of a new class of anti-angiogenic agents based on ruthenium clusters.

Sci Rep 2013 ;3:1485

1] Institute of Chemical Sciences and Engineering, Swiss Federal Institute of Technology (EPFL), CH-1015 Lausanne, Switzerland [2] Department of Chemistry, Moscow State University, Leninskie Gory, 119991, Moscow, Russia.

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http://dx.doi.org/10.1038/srep01485DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6504821PMC
June 2014

Anticancer metallodrug research analytically painting the "omics" picture--current developments and future trends.

Anal Bioanal Chem 2013 Feb 16;405(6):1791-808. Epub 2012 Oct 16.

Institute of Analytical Chemistry, University of Vienna, Waehringer Str. 42, 1090 Vienna, Austria.

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http://dx.doi.org/10.1007/s00216-012-6450-4DOI Listing
February 2013

Combination of metallomics and proteomics to study the effects of the metallodrug RAPTA-T on human cancer cells.

Metallomics 2012 Nov 26;4(11):1185-96. Epub 2012 Sep 26.

Department of Analytical Chemistry, Ruhr University of Bochum, Universitaetsstrasse 150, Bochum, 44801, Germany.

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http://dx.doi.org/10.1039/c2mt20070hDOI Listing
November 2012

Bioanalysis young investigator: Michael Groessl.

Bioanalysis 2012 May;4(8):873-4

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http://dx.doi.org/10.4155/bio.12.62DOI Listing
May 2012

Anthracene-tethered ruthenium(II) arene complexes as tools to visualize the cellular localization of putative organometallic anticancer compounds.

Inorg Chem 2012 Mar 6;51(6):3633-9. Epub 2012 Mar 6.

Institute of Chemical Sciences and Engineering, Swiss Federal Institute of Technology (EPFL), 1015 Lausanne, Switzerland.

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http://dx.doi.org/10.1021/ic202530jDOI Listing
March 2012

Bioanalytical and biophysical techniques for the elucidation of the mode of action of metal-based drugs.

Curr Top Med Chem 2011 ;11(21):2632-46

Institut des Sciences et Ingénierie Chimiques, École Polytechnique Fédérale de Lausanne (EPFL), CH-1015 Lausanne, Switzerland.

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http://dx.doi.org/10.2174/156802611798040705DOI Listing
February 2012

Maleimide-functionalised organoruthenium anticancer agents and their binding to thiol-containing biomolecules.

Chem Commun (Camb) 2012 Feb 14;48(10):1475-7. Epub 2011 Oct 14.

University of Vienna, Institute of Inorganic Chemistry, Waehringer Str. 42, A-1090 Vienna, Austria.

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http://dx.doi.org/10.1039/c1cc14713gDOI Listing
February 2012

Mass spectrometric and theoretical study of polyiodides: the connection between solid state, solution, and gas phases.

Inorg Chem 2011 Oct 1;50(19):9728-33. Epub 2011 Sep 1.

Institut des Sciences et Ingénierie Chimiques, Ecole Polytechnique Fédérale de Lausanne, CH-1015 Lausanne, Switzerland.

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http://dx.doi.org/10.1021/ic201642kDOI Listing
October 2011

Multinuclear cytotoxic metallodrugs: physicochemical characterization and biological properties of novel heteronuclear gold-titanium complexes.

Inorg Chem 2011 Oct 29;50(19):9472-80. Epub 2011 Aug 29.

Institut de Chimie Moléculaire de l'Université de Bourgogne, UMR 5260 CNRS-Université de Bourgogne, 9 avenue A. Savary, BP 47870, 21078 Dijon, France.

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http://dx.doi.org/10.1021/ic201155yDOI Listing
October 2011

Nanoscalic silver possesses broad-spectrum antimicrobial activities and exhibits fewer toxicological side effects than silver sulfadiazine.

Nanomedicine 2012 May 10;8(4):478-88. Epub 2011 Aug 10.

Division of Immunology, Allergy and Infectious Diseases, Department of Dermatology, Medical University of Vienna, Vienna, Austria.

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https://linkinghub.elsevier.com/retrieve/pii/S15499634110028
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http://dx.doi.org/10.1016/j.nano.2011.07.005DOI Listing
May 2012

Cellular uptake and subcellular distribution of ruthenium-based metallodrugs under clinical investigation versus cisplatin.

Metallomics 2011 Jun 11;3(6):591-9. Epub 2011 Mar 11.

Institut des Sciences et Ingénierie Chimiques, École Polytechnique Fédérale de Lausanne, 1015 Lausanne, Switzerland.

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http://dx.doi.org/10.1039/c0mt00101eDOI Listing
June 2011

Metal-based inhibition of poly(ADP-ribose) polymerase--the guardian angel of DNA.

J Med Chem 2011 Apr 3;54(7):2196-206. Epub 2011 Mar 3.

Unidade de Ciências Químicas e Radiofarmacêuticas, Instituto Tecnológico e Nuclear, Estrada Nacional 10, 2686-953 Sacavém, Portugal.

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http://dx.doi.org/10.1021/jm2000135DOI Listing
April 2011

A ruthenium antimetastasis agent forms specific histone protein adducts in the nucleosome core.

Chemistry 2011 Mar 23;17(13):3562-6. Epub 2011 Feb 23.

Division of Structural and Computational Biology, School of Biological Sciences, Nanyang Technological University, 60 Nanyang Drive, Singapore 637551.

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http://dx.doi.org/10.1002/chem.201100298DOI Listing
March 2011

Reactivity of anticancer metallodrugs with serum proteins: new insights from size exclusion chromatography-ICP-MS and ESI-MS.

J Anal At Spectrom 2010 Mar;25(3):305-313

Institut des Sciences et Ingénierie Chimiques, Ecole Polytechnique Fédérale de Lausanne (EPFL), CH-1015 Lausanne, Switzerland. ; ; Tel: +41 (0)21 6939860.

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http://dx.doi.org/10.1039/B922701FDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2999900PMC
March 2010

Tuning of lipophilicity and cytotoxic potency by structural variation of anticancer platinum(IV) complexes.

J Inorg Biochem 2011 Jan 1;105(1):46-51. Epub 2010 Oct 1.

University of Vienna, Institute of Inorganic Chemistry, Waehringer Str. 42, A-1090 Vienna, Austria.

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http://dx.doi.org/10.1016/j.jinorgbio.2010.09.006DOI Listing
January 2011

The serum protein binding of pharmacologically active gallium(III) compounds assessed by hyphenated CE-MS techniques.

Electrophoresis 2009 Aug;30(15):2720-7

University of Vienna, Institute of Inorganic Chemistry, Vienna, Austria.

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http://doi.wiley.com/10.1002/elps.200800745
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http://dx.doi.org/10.1002/elps.200800745DOI Listing
August 2009

CZE-ICP-MS as a tool for studying the hydrolysis of ruthenium anticancer drug candidates and their reactivity towards the DNA model compound dGMP.

J Inorg Biochem 2008 May-Jun;102(5-6):1060-5. Epub 2007 Dec 14.

Institute of Inorganic Chemistry, University of Vienna, Waehringer Street 42, A-1090 Vienna, Austria.

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http://dx.doi.org/10.1016/j.jinorgbio.2007.11.018DOI Listing
July 2008

A glucose derivative as natural alternative to the cyclohexane-1,2-diamine ligand in the anticancer drug oxaliplatin?

ChemMedChem 2007 Apr;2(4):505-14

Institute of Inorganic Chemistry, Faculty of Chemistry, University of Vienna, Waehringer Str. 42, 1090 Vienna, Austria.

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http://dx.doi.org/10.1002/cmdc.200600279DOI Listing
April 2007