Michael Gnant

Michael Gnant

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New evidence and hope for young patients with breast cancer.

Authors:
Michael Gnant

Eur J Cancer 2019 Sep 30;118:166-168. Epub 2019 Jul 30.

Medical University of Vienna, Vienna, Austria. Electronic address:

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http://dx.doi.org/10.1016/j.ejca.2019.06.007DOI Listing
September 2019

Breast cancer.

Nat Rev Dis Primers 2019 Sep 23;5(1):66. Epub 2019 Sep 23.

Breast Unit, Champalimaud Clinical Center/Champalimaud Foundation, Lisbon, Portugal.

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http://dx.doi.org/10.1038/s41572-019-0111-2DOI Listing
September 2019

Challenges and Controversies in Breast Surgery.

Authors:
Michael Gnant

Breast Care (Basel) 2019 Aug 7;14(4):185-187. Epub 2019 Aug 7.

Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.1159/000502134DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6751473PMC
August 2019

Denosumab in early-stage breast cancer - Authors' reply.

Lancet Oncol 2019 May;20(5):236

Department of Statistics, Austrian Breast & Colorectal Cancer Study Group, Vienna, Austria.

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http://dx.doi.org/10.1016/S1470-2045(19)30228-1DOI Listing
May 2019

Sarcopenia and sarcopenic obesity are independent adverse prognostic factors in resectable pancreatic ductal adenocarcinoma.

PLoS One 2019 6;14(5):e0215915. Epub 2019 May 6.

Division of General Surgery, Department of Surgery, Pancreatic Cancer Unit, Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0215915PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6502449PMC
May 2019

Systemic Immune-Inflammation Index (SII) Predicts Poor Survival in Pancreatic Cancer Patients Undergoing Resection.

J Gastrointest Surg 2019 Mar 28. Epub 2019 Mar 28.

Department of Surgery, Comprehensive Cancer Center (CCC), Medical University Vienna and Pancreatic Cancer Unit, Spitalgasse 23, 1090, Vienna, Austria.

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http://link.springer.com/10.1007/s11605-019-04187-z
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http://dx.doi.org/10.1007/s11605-019-04187-zDOI Listing
March 2019

Postmastectomy Radiation Therapy in Women with T1-T2 Tumors and 1 to 3 Positive Lymph Nodes: Analysis of the Breast International Group 02-98 Trial.

Int J Radiat Oncol Biol Phys 2018 06 6;101(2):316-324. Epub 2018 Feb 6.

International Breast Cancer Study Group, Bern, Switzerland; Peter MacCallum Cancer Centre, Melbourne, Australia; St. Vincents's Hospital, University of Melbourne, Australia; Breast Cancer Trials Australia & New Zealand, University of Newcastle, Newcastle, Australia.

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http://dx.doi.org/10.1016/j.ijrobp.2018.01.105DOI Listing
June 2018

Evolution of Targeted Therapy in Breast Cancer: Where Precision Medicine Began.

Am Soc Clin Oncol Educ Book 2018 May;38:78-86

From the Winship Cancer Institute, Emory University School of Medicine, Atlanta, GA; University of Iowa, Iowa City, IA; Medical University of Vienna and Austrian Breast and Colorectal Cancer Study Group, Vienna, Austria; UNC Lineberger Comprehensive Cancer Center, Chapel Hill, NC.

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http://dx.doi.org/10.1200/EDBK_201037DOI Listing
May 2018

Explained variation in shared frailty models.

Stat Med 2018 04 28;37(9):1482-1490. Epub 2017 Dec 28.

Center for Medical Statistics, Informatics, and Intelligent Systems, Medical University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.1002/sim.7592DOI Listing
April 2018

High Accumulation of Metformin in Colonic Tissue of Subjects With Diabetes or the Metabolic Syndrome.

Gastroenterology 2018 04 8;154(5):1543-1545. Epub 2018 Mar 8.

Division of Medical Oncology, E.O. Ospedali Galliera, Genoa, Italy and Wolfson Institute of Preventive Medicine, Queen Mary University of London, London, United Kingdom.

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http://dx.doi.org/10.1053/j.gastro.2017.12.040DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6002843PMC
April 2018

Adjuvant Bisphosphonate Therapy in Postmenopausal Breast Cancer.

Curr Treat Options Oncol 2018 03 12;19(4):18. Epub 2018 Mar 12.

Department of Surgery, Comprehensive Cancer Center, Medical University of Vienna, Waehringer Guertel 18-20, A-1090, Wien, Austria.

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http://dx.doi.org/10.1007/s11864-018-0535-zDOI Listing
March 2018

Therapeutic Bone-Modifying Agents in the Nonmetastatic Breast Cancer Setting: The Controversy and a Value Assessment.

Am Soc Clin Oncol Educ Book 2017 ;37:116-122

From the Department of Surgery, Comprehensive Cancer Center, Medical University of Vienna, Waehringer Guertel, Austria; University of Michigan, Ann Arbor, MI; Hematology/Oncology Division, Harvard Medical School, Beth Israel Deaconess Medical Center, Boston, MA.

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http://dx.doi.org/10.1200/EDBK_177357DOI Listing
December 2017

Sized Influences Nodal Status in Women Aged #70 with Endocrine Responsive Breast Cancer.

Ann Surg Oncol 2017 12 20;24(Suppl 3):555-556. Epub 2017 Nov 20.

Department of General Surgery, University Vienna General Hospital, Veinna, Austria.

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http://dx.doi.org/10.1245/s10434-017-6156-0DOI Listing
December 2017

Optimal duration of adjuvant endocrine therapy: how to apply the newest data.

Ther Adv Med Oncol 2017 Nov 27;9(11):679-692. Epub 2017 Oct 27.

Department of Surgery and Comprehensive Cancer Center, Medical University of Vienna, Waehringer Guertel 18-20, 1090, Vienna, Austria.

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http://journals.sagepub.com/doi/10.1177/1758834017732966
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http://dx.doi.org/10.1177/1758834017732966DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5764154PMC
November 2017

Objective breast symmetry analysis with the breast analyzing tool (BAT): improved tool for clinical trials.

Breast Cancer Res Treat 2017 Jul 2;164(2):421-427. Epub 2017 May 2.

Department of Surgery, Medical University of Vienna, Waehringer Guertel 18-20, 1090, Vienna, Austria.

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http://dx.doi.org/10.1007/s10549-017-4255-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5487750PMC
July 2017

St. Gallen/Vienna 2017: A Brief Summary of the Consensus Discussion about Escalation and De-Escalation of Primary Breast Cancer Treatment.

Breast Care (Basel) 2017 May 26;12(2):102-107. Epub 2017 Apr 26.

Department of Gynecology, Martin-Luther-University, Halle/Saale, Germany.

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http://dx.doi.org/10.1159/000475698DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5447163PMC
May 2017

Comparative Efficacy and Safety of Adjuvant Letrozole Versus Anastrozole in Postmenopausal Patients With Hormone Receptor-Positive, Node-Positive Early Breast Cancer: Final Results of the Randomized Phase III Femara Versus Anastrozole Clinical Evaluation (FACE) Trial.

J Clin Oncol 2017 Apr 23;35(10):1041-1048. Epub 2017 Jan 23.

Ian Smith and Mitch Dowsett, Royal Marsden Hospital; Institute of Cancer Research, London, United Kingdom; Denise Yardley and Howard Burris, Sarah Cannon Research Institute; Tennessee Oncology, Nashville, TN; Richard De Boer, Royal Melbourne and Western Hospitals, Melbourne, Australia; Dino Amadori, Istituto Scientifico Romagnolo per lo Studio e la Cura del Tumori Istituto di Ricovero eCura a Carattere Scientifico, Meldola; Lisa Comarella, CROS NT, Verona, Italy; Kristi McIntyre and Joyce O'Shaughnessy, Texas Oncology, US Oncology; Joyce O'Shaughnessy, Baylor University Medical Center; Baylor Charles A. Sammons Cancer Center; The US Oncology Network, Dallas, TX; Bent Ejlertsen, Danish Breast Cancer Cooperative Group, Rigshospitalet, Copenhagen, Denmark; Michael Gnant, Medical University of Vienna, Vienna, Austria; Walter Jonat, Universitätsklinikum Schleswig-Holstein, Kiel, Germany; Kathleen I. Pritchard, Sunnybrook Odette Cancer Centre, University of Toronto, Toronto, Ontario, Canada; Lowell Hart, Florida Cancer Specialists, Fort Myers, FL; Susan Poggio and Barbara Wamil, Novartis Pharmaceuticals Corporation, East Hanover, NJ; and Herve Salomon, Novartis Pharma, Rueil-Malmaison, France.

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http://dx.doi.org/10.1200/JCO.2016.69.2871DOI Listing
April 2017

Breast cancer.

Lancet 2017 03 17;389(10074):1134-1150. Epub 2016 Nov 17.

Department of Surgery and Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria.

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https://linkinghub.elsevier.com/retrieve/pii/S01406736163189
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http://dx.doi.org/10.1016/S0140-6736(16)31891-8DOI Listing
March 2017

Adjuvant Bisphosphonates and Breast Cancer Survival.

Annu Rev Med 2016 28;67:1-10. Epub 2015 Aug 28.

Department of Surgery and Comprehensive Cancer Center, Medical University of Vienna, A-1090 Vienna, Austria; email:

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http://www.annualreviews.org/doi/10.1146/annurev-med-053014-
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http://dx.doi.org/10.1146/annurev-med-053014-103600DOI Listing
October 2016

Palbociclib for the treatment of postmenopausal breast cancer - an update.

Expert Opin Pharmacother 2016 14;17(2):255-63. Epub 2016 Jan 14.

a Department of Internal Medicine I/Division of Oncology , Medical University of Vienna , Vienna , Austria.

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http://dx.doi.org/10.1517/14656566.2016.1133590DOI Listing
June 2016

Pathological complete remission and long-term outcome-what do we know in 2016?

Lancet Oncol 2016 06 11;17(6):693-694. Epub 2016 May 11.

Department of Internal Medicine I, Breast Health Centre, Comprehensive Cancer Centre, Medical University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.1016/S1470-2045(16)30038-9DOI Listing
June 2016

Editorial comment on 'Effects of neoadjuvant chemotherapy with or without zoledronic acid on pathological response: A meta-analysis of randomised trials'.

Authors:
Michael Gnant

Eur J Cancer 2016 05 28;59:125-127. Epub 2016 Mar 28.

Department of Surgery and Comprehensive Cancer Center, Medical University of Vienna, Austria. Electronic address:

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http://dx.doi.org/10.1016/j.ejca.2016.02.009DOI Listing
May 2016

Breast Cancer Is Our Global Responsibility.

Breast Care (Basel) 2015 Dec 16;10(6):360. Epub 2015 Dec 16.

Department of Gynecology, Martin-Luther-University, Halle an der Saale, Germany.

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https://www.karger.com/Article/FullText/443159
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http://dx.doi.org/10.1159/000443159DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4789920PMC
December 2015

Targeting bone microenvironment: Clinical implications.

Authors:
Michael Gnant

Breast 2015 Nov 1;24 Suppl 2:S49-50. Epub 2015 Aug 1.

Department of Surgery, Comprehensive Cancer Center, Medical University of Vienna, A-1090 Wien, Währinger Gürtel 18-20, Austria. Electronic address:

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http://dx.doi.org/10.1016/j.breast.2015.07.012DOI Listing
November 2015

St.Gallen-2015 in Vienna: News from a successful breast cancer conference transposition!

Breast 2015 Nov 4;24 Suppl 2:S1. Epub 2015 Oct 4.

Department of Surgery, and Comprehensive Cancer Center, Medical University of Vienna, Austria; Austrian Breast and Colorectal Cancer Study Group (ABCSG), Vienna, Austria.

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https://linkinghub.elsevier.com/retrieve/pii/S09609776150016
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http://dx.doi.org/10.1016/j.breast.2015.07.030DOI Listing
November 2015

Denosumab and fracture risk in women with breast cancer - Author's reply.

Authors:
Michael Gnant

Lancet 2015 Nov 20;386(10008):2057-2058. Epub 2015 Nov 20.

Department of Surgery and Comprehensive Cancer Center, Medical University of Vienna, A-1090 Vienna, Austria. Electronic address:

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http://dx.doi.org/10.1016/S0140-6736(15)00975-7DOI Listing
November 2015

Bevacizumab: no comeback in early breast cancer?

Lancet Oncol 2015 Sep 10;16(9):1001-1003. Epub 2015 Aug 10.

Department of Internal Medicine I, Breast Health Center, Comprehensive Cancer Center, Medical University of Vienna, Vienna 1090, Austria.

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http://www.thelancet.com/pdfs/journals/lanonc/PIIS1470-2045(
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http://linkinghub.elsevier.com/retrieve/pii/S147020451500124
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http://dx.doi.org/10.1016/S1470-2045(15)00124-2DOI Listing
September 2015

St. Gallen/Vienna 2015: A Brief Summary of the Consensus Discussion.

Breast Care (Basel) 2015 Apr;10(2):124-30

Breast Center, Department of Obstetrics and Gynecology, University of Munich, Germany.

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https://www.karger.com/Article/FullText/430488
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http://dx.doi.org/10.1159/000430488DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4464099PMC
April 2015

Prediction of late distant recurrence after 5 years of endocrine treatment: a combined analysis of patients from the Austrian breast and colorectal cancer study group 8 and arimidex, tamoxifen alone or in combination randomized trials using the PAM50 risk of recurrence score.

J Clin Oncol 2015 Mar 20;33(8):916-22. Epub 2014 Oct 20.

Ivana Sestak, Jack Cuzick, Queen Mary University; Mitch Dowsett, Elena Lopez-Knowles, Royal Marsden Hospital, London, United Kingdom; Martin Filipits, Peter Dubsky, Michael Gnant, Medical University of Vienna; Christian Fesl, Austrian Breast and Colorectal Cancer Study Group, Vienna, Austria; John Wayne Cowens, Sean Ferree, NanoString Technologies, Seattle, WA; and Carl Shaper, MyRAQA, Redwood Shores, CA.

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http://dx.doi.org/10.1200/JCO.2014.55.6894DOI Listing
March 2015

Standardization of morbidity assessment in breast cancer surgery using the Clavien Dindo Classification.

Int J Surg 2014 31;12(4):334-9. Epub 2014 Jan 31.

Department of General Surgery, Medical University of Vienna, Breast Health Center, Währinger Gürtel 18-20, Vienna, Austria.

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http://dx.doi.org/10.1016/j.ijsu.2014.01.012DOI Listing
January 2015

CDK4/6 inhibitors in luminal breast cancer.

Lancet Oncol 2015 Jan 16;16(1):2-3. Epub 2014 Dec 16.

Internal Medicine I, Breast Health Center, Comprehensive Cancer Center, Medical University of Vienna, A-1090 Vienna, Austria.

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http://dx.doi.org/10.1016/S1470-2045(14)71188-XDOI Listing
January 2015

Co-overexpression of HER2/HER3 is a predictor of impaired survival in breast cancer patients.

Breast 2014 Oct 10;23(5):637-43. Epub 2014 Jul 10.

Comprehensive Cancer Center Vienna, Medical University of Vienna, Austria; Department of Pathology, Medical University of Vienna, Austria.

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http://dx.doi.org/10.1016/j.breast.2014.06.011DOI Listing
October 2014

HER2-positive breast cancer: a new piece of the puzzle.

Lancet Oncol 2014 Jun 2;15(7):668-9. Epub 2014 May 2.

Department of Internal Medicine I, Breast Health Center, Comprehensive Cancer Center, Medical University of Vienna, A-1090 Vienna, Austria.

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http://dx.doi.org/10.1016/S1470-2045(14)70192-5DOI Listing
June 2014

A phase II trial of two durations of Bevacizumab added to neoadjuvant gemcitabine for borderline and locally advanced pancreatic cancer.

Anticancer Res 2014 May;34(5):2377-84

MD FACS, Department of Surgery and Comprehensive Cancer Center Medical University of Vienna, Waehringer Guertel 18-20, 1090 Vienna, Austria.

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May 2014

Modern therapeutic concepts of early breast cancer.

Authors:
Michael Gnant

Breast Care (Basel) 2014 May;9(2):85-6

Department of Surgery and Comprehensive Cancer Center MUW/AKH, Vienna, Austria.

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http://dx.doi.org/10.1159/000362528DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4038315PMC
May 2014

Role of bisphosphonates in postmenopausal women with breast cancer.

Authors:
Michael Gnant

Cancer Treat Rev 2014 Apr 29;40(3):476-84. Epub 2013 Jul 29.

Department of Surgery, Comprehensive Cancer Center, Medical University of Vienna, Austria. Electronic address:

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http://dx.doi.org/10.1016/j.ctrv.2013.07.003DOI Listing
April 2014

The PAM50 risk-of-recurrence score predicts risk for late distant recurrence after endocrine therapy in postmenopausal women with endocrine-responsive early breast cancer.

Clin Cancer Res 2014 Mar 11;20(5):1298-305. Epub 2014 Feb 11.

Authors' Affiliations: Departments of Medicine I, Pathology, and Surgery; Department of Obstetrics and Gynecology, Comprehensive Cancer Center Vienna, Medical University of Vienna; Austrian Breast and Colorectal Cancer Study Group, Vienna; Departments of Internal Medicine III and Pathology, Paracelsus Private Medical University, Salzburg; Departments of Internal Medicine and Pathology, Medical University of Graz, Graz; Departments of Pathology and Surgery, Sisters of Charity Hospital and Cancer Center, Linz; Department of Obstetrics and Gynecology, Medical University of Innsbruck, Innsbruck; Department of Surgery, General Hospital Baden, Baden, Austria; Myraqa, Redwood Shores, California; NanoString Technologies, Seattle, Washington; and British Columbia Cancer Agency, Vancouver, British Columbia, Canada.

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http://dx.doi.org/10.1158/1078-0432.CCR-13-1845DOI Listing
March 2014

Distal gastrectomy in pancreaticoduodenectomy is associated with accelerated gastric emptying, enhanced postprandial release of GLP-1, and improved insulin sensitivity.

J Gastrointest Surg 2014 Jan 4;18(1):52-9. Epub 2013 Sep 4.

Department of Surgery, Allgemeines Krankenhaus (AKH), Medical University of Vienna, Währinger Gürtel 18, 1090, Vienna, Austria.

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http://dx.doi.org/10.1007/s11605-013-2283-5DOI Listing
January 2014

Follow-up after breast cancer diagnosis.

Breast Care (Basel) 2013 Dec;8(6):457-60

Department of Medicine, Harvard Medical School, Dana-Farber Cancer Institute, Boston, MA, USA.

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http://dx.doi.org/10.1159/000357586DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3919482PMC
December 2013

Bone effects of mammalian target of rapamycin (mTOR) inhibition with everolimus.

Crit Rev Oncol Hematol 2013 Aug 6;87(2):101-11. Epub 2013 Jul 6.

Department of Gynecology, Philipps-University of Marburg, Marburg, Germany.

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https://linkinghub.elsevier.com/retrieve/pii/S10408428130011
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http://dx.doi.org/10.1016/j.critrevonc.2013.05.015DOI Listing
August 2013

Guidelines: usefulness and limitations.

Authors:
Michael Gnant

Breast Care (Basel) 2013 Jun;8(3):172-3

Department of Surgery and Comprehensive Cancer Center, Medical University of Vienna, Austria.

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http://dx.doi.org/10.1159/000353791DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3728632PMC
June 2013

St. Gallen 2013: brief preliminary summary of the consensus discussion.

Breast Care (Basel) 2013 May;8(2):102-9

Breast Center, Department of Obstetrics and Gynecology, University of Munich, Germany.

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http://dx.doi.org/10.1159/000351193DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3683952PMC
May 2013

Plasma HMGB-1 after the initial dose of epirubicin/docetaxel in cancer.

Eur J Clin Invest 2013 Mar 25;43(3):286-91. Epub 2013 Jan 25.

Surgical Research Laboratories, Department of Surgery, Medical University of Vienna, Vienna, Austria.

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http://doi.wiley.com/10.1111/eci.12043
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http://dx.doi.org/10.1111/eci.12043DOI Listing
March 2013