Publications by authors named "Michael Gnant"

100Publications

More is not always better-what can be learned from the D-CARE trial.

Ann Transl Med 2020 Aug;8(16):1034

Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.21037/atm.2020.04.31DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7475453PMC
August 2020

Correction to: The Prognostic Index Independently Predicts Survival in Patients with Pancreatic Ductal Adenocarcinoma Undergoing Resection.

Ann Surg Oncol 2020 Aug 5. Epub 2020 Aug 5.

Division of General Surgery, Department of Surgery, Medical University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.1245/s10434-020-09010-7DOI Listing
August 2020

Prognostic Value of EndoPredict in Women with Hormone Receptor-Positive, HER2-Negative Invasive Lobular Breast Cancer.

Clin Cancer Res 2020 Sep 19;26(17):4682-4687. Epub 2020 Jun 19.

Medical University of Vienna, Department of Surgery and Comprehensive Cancer Centre, Vienna, Austria.

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http://dx.doi.org/10.1158/1078-0432.CCR-20-0260DOI Listing
September 2020

Predictive Value of Molecular Subtypes in Premenopausal Women with Hormone Receptor-positive Early Breast Cancer: Results from the ABCSG Trial 5.

Clin Cancer Res 2020 Jun 16. Epub 2020 Jun 16.

Institute of Cancer Research, Department of Medicine I, Breast Health Center and Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.1158/1078-0432.CCR-20-0673DOI Listing
June 2020

The Prognostic Index Independently Predicts Survival in Patients with Pancreatic Ductal Adenocarcinoma Undergoing Resection.

Ann Surg Oncol 2020 Jun 3;27(6):2017-2024. Epub 2020 Jan 3.

Pancreatic Cancer Unit, Division of General Surgery, Department of Surgery, Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.1245/s10434-019-08161-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7210221PMC
June 2020

St. Gallen/Vienna 2019: A Brief Summary of the Consensus Discussion on the Optimal Primary Breast Cancer Treatment.

Breast Care (Basel) 2019 Apr 4;14(2):103-110. Epub 2019 Apr 4.

Breast Center, Department of Obstetrics and Gynecology, University of Munich (LMU), Munich, Germany.

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http://dx.doi.org/10.1159/000499931DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6886108PMC
April 2019

Challenges and Controversies in Breast Surgery.

Authors:
Michael Gnant

Breast Care (Basel) 2019 Aug 7;14(4):185-187. Epub 2019 Aug 7.

Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.1159/000502134DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6751473PMC
August 2019

Breast cancer.

Nat Rev Dis Primers 2019 09 23;5(1):66. Epub 2019 Sep 23.

Breast Unit, Champalimaud Clinical Center/Champalimaud Foundation, Lisbon, Portugal.

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http://dx.doi.org/10.1038/s41572-019-0111-2DOI Listing
September 2019

New evidence and hope for young patients with breast cancer.

Authors:
Michael Gnant

Eur J Cancer 2019 09 30;118:166-168. Epub 2019 Jul 30.

Medical University of Vienna, Vienna, Austria. Electronic address:

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http://dx.doi.org/10.1016/j.ejca.2019.06.007DOI Listing
September 2019

Sarcopenia and sarcopenic obesity are independent adverse prognostic factors in resectable pancreatic ductal adenocarcinoma.

PLoS One 2019 6;14(5):e0215915. Epub 2019 May 6.

Division of General Surgery, Department of Surgery, Pancreatic Cancer Unit, Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0215915PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6502449PMC
January 2020

Denosumab in early-stage breast cancer - Authors' reply.

Lancet Oncol 2019 05;20(5):236

Department of Statistics, Austrian Breast & Colorectal Cancer Study Group, Vienna, Austria.

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http://dx.doi.org/10.1016/S1470-2045(19)30228-1DOI Listing
May 2019

Systemic Immune-Inflammation Index (SII) Predicts Poor Survival in Pancreatic Cancer Patients Undergoing Resection.

J Gastrointest Surg 2020 Mar 28;24(3):610-618. Epub 2019 Mar 28.

Department of Surgery, Comprehensive Cancer Center (CCC), Medical University Vienna and Pancreatic Cancer Unit, Spitalgasse 23, 1090, Vienna, Austria.

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http://link.springer.com/10.1007/s11605-019-04187-z
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http://dx.doi.org/10.1007/s11605-019-04187-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7064450PMC
March 2020

Evolution of Targeted Therapy in Breast Cancer: Where Precision Medicine Began.

Am Soc Clin Oncol Educ Book 2018 May;38:78-86

From the Winship Cancer Institute, Emory University School of Medicine, Atlanta, GA; University of Iowa, Iowa City, IA; Medical University of Vienna and Austrian Breast and Colorectal Cancer Study Group, Vienna, Austria; UNC Lineberger Comprehensive Cancer Center, Chapel Hill, NC.

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http://dx.doi.org/10.1200/EDBK_201037DOI Listing
May 2018

Postmastectomy Radiation Therapy in Women with T1-T2 Tumors and 1 to 3 Positive Lymph Nodes: Analysis of the Breast International Group 02-98 Trial.

Int J Radiat Oncol Biol Phys 2018 06 6;101(2):316-324. Epub 2018 Feb 6.

International Breast Cancer Study Group, Bern, Switzerland; Peter MacCallum Cancer Centre, Melbourne, Australia; St. Vincents's Hospital, University of Melbourne, Australia; Breast Cancer Trials Australia & New Zealand, University of Newcastle, Newcastle, Australia.

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http://dx.doi.org/10.1016/j.ijrobp.2018.01.105DOI Listing
June 2018

Adjuvant Bisphosphonate Therapy in Postmenopausal Breast Cancer.

Curr Treat Options Oncol 2018 03 12;19(4):18. Epub 2018 Mar 12.

Department of Surgery, Comprehensive Cancer Center, Medical University of Vienna, Waehringer Guertel 18-20, A-1090, Wien, Austria.

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http://dx.doi.org/10.1007/s11864-018-0535-zDOI Listing
March 2018

High Accumulation of Metformin in Colonic Tissue of Subjects With Diabetes or the Metabolic Syndrome.

Gastroenterology 2018 04 8;154(5):1543-1545. Epub 2018 Mar 8.

Division of Medical Oncology, E.O. Ospedali Galliera, Genoa, Italy and Wolfson Institute of Preventive Medicine, Queen Mary University of London, London, United Kingdom.

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http://dx.doi.org/10.1053/j.gastro.2017.12.040DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6002843PMC
April 2018

Optimal duration of adjuvant endocrine therapy: how to apply the newest data.

Ther Adv Med Oncol 2017 Nov 27;9(11):679-692. Epub 2017 Oct 27.

Department of Surgery and Comprehensive Cancer Center, Medical University of Vienna, Waehringer Guertel 18-20, 1090, Vienna, Austria.

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http://journals.sagepub.com/doi/10.1177/1758834017732966
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http://dx.doi.org/10.1177/1758834017732966DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5764154PMC
November 2017

Explained variation in shared frailty models.

Stat Med 2018 04 28;37(9):1482-1490. Epub 2017 Dec 28.

Center for Medical Statistics, Informatics, and Intelligent Systems, Medical University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.1002/sim.7592DOI Listing
April 2018

Sized Influences Nodal Status in Women Aged #70 with Endocrine Responsive Breast Cancer.

Ann Surg Oncol 2017 12 20;24(Suppl 3):555-556. Epub 2017 Nov 20.

Department of General Surgery, University Vienna General Hospital, Veinna, Austria.

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http://dx.doi.org/10.1245/s10434-017-6156-0DOI Listing
December 2017

Therapeutic Bone-Modifying Agents in the Nonmetastatic Breast Cancer Setting: The Controversy and a Value Assessment.

Am Soc Clin Oncol Educ Book 2017 ;37:116-122

From the Department of Surgery, Comprehensive Cancer Center, Medical University of Vienna, Waehringer Guertel, Austria; University of Michigan, Ann Arbor, MI; Hematology/Oncology Division, Harvard Medical School, Beth Israel Deaconess Medical Center, Boston, MA.

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http://dx.doi.org/10.1200/EDBK_177357DOI Listing
December 2017

St. Gallen/Vienna 2017: A Brief Summary of the Consensus Discussion about Escalation and De-Escalation of Primary Breast Cancer Treatment.

Breast Care (Basel) 2017 May 26;12(2):102-107. Epub 2017 Apr 26.

Department of Gynecology, Martin-Luther-University, Halle/Saale, Germany.

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http://dx.doi.org/10.1159/000475698DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5447163PMC
May 2017

Objective breast symmetry analysis with the breast analyzing tool (BAT): improved tool for clinical trials.

Breast Cancer Res Treat 2017 Jul 2;164(2):421-427. Epub 2017 May 2.

Department of Surgery, Medical University of Vienna, Waehringer Guertel 18-20, 1090, Vienna, Austria.

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http://dx.doi.org/10.1007/s10549-017-4255-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5487750PMC
July 2017

Comparative Efficacy and Safety of Adjuvant Letrozole Versus Anastrozole in Postmenopausal Patients With Hormone Receptor-Positive, Node-Positive Early Breast Cancer: Final Results of the Randomized Phase III Femara Versus Anastrozole Clinical Evaluation (FACE) Trial.

J Clin Oncol 2017 Apr 23;35(10):1041-1048. Epub 2017 Jan 23.

Ian Smith and Mitch Dowsett, Royal Marsden Hospital; Institute of Cancer Research, London, United Kingdom; Denise Yardley and Howard Burris, Sarah Cannon Research Institute; Tennessee Oncology, Nashville, TN; Richard De Boer, Royal Melbourne and Western Hospitals, Melbourne, Australia; Dino Amadori, Istituto Scientifico Romagnolo per lo Studio e la Cura del Tumori Istituto di Ricovero eCura a Carattere Scientifico, Meldola; Lisa Comarella, CROS NT, Verona, Italy; Kristi McIntyre and Joyce O'Shaughnessy, Texas Oncology, US Oncology; Joyce O'Shaughnessy, Baylor University Medical Center; Baylor Charles A. Sammons Cancer Center; The US Oncology Network, Dallas, TX; Bent Ejlertsen, Danish Breast Cancer Cooperative Group, Rigshospitalet, Copenhagen, Denmark; Michael Gnant, Medical University of Vienna, Vienna, Austria; Walter Jonat, Universitätsklinikum Schleswig-Holstein, Kiel, Germany; Kathleen I. Pritchard, Sunnybrook Odette Cancer Centre, University of Toronto, Toronto, Ontario, Canada; Lowell Hart, Florida Cancer Specialists, Fort Myers, FL; Susan Poggio and Barbara Wamil, Novartis Pharmaceuticals Corporation, East Hanover, NJ; and Herve Salomon, Novartis Pharma, Rueil-Malmaison, France.

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http://dx.doi.org/10.1200/JCO.2016.69.2871DOI Listing
April 2017

Breast cancer.

Lancet 2017 03 17;389(10074):1134-1150. Epub 2016 Nov 17.

Department of Surgery and Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria.

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https://linkinghub.elsevier.com/retrieve/pii/S01406736163189
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http://dx.doi.org/10.1016/S0140-6736(16)31891-8DOI Listing
March 2017

Pathological complete remission and long-term outcome-what do we know in 2016?

Lancet Oncol 2016 06 11;17(6):693-694. Epub 2016 May 11.

Department of Internal Medicine I, Breast Health Centre, Comprehensive Cancer Centre, Medical University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.1016/S1470-2045(16)30038-9DOI Listing
June 2016

Editorial comment on 'Effects of neoadjuvant chemotherapy with or without zoledronic acid on pathological response: A meta-analysis of randomised trials'.

Authors:
Michael Gnant

Eur J Cancer 2016 05 28;59:125-127. Epub 2016 Mar 28.

Department of Surgery and Comprehensive Cancer Center, Medical University of Vienna, Austria. Electronic address:

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http://dx.doi.org/10.1016/j.ejca.2016.02.009DOI Listing
May 2016

Breast Cancer Is Our Global Responsibility.

Breast Care (Basel) 2015 Dec 16;10(6):360. Epub 2015 Dec 16.

Department of Gynecology, Martin-Luther-University, Halle an der Saale, Germany.

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https://www.karger.com/Article/FullText/443159
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http://dx.doi.org/10.1159/000443159DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4789920PMC
December 2015

Denosumab and fracture risk in women with breast cancer - Author's reply.

Authors:
Michael Gnant

Lancet 2015 Nov 20;386(10008):2057-2058. Epub 2015 Nov 20.

Department of Surgery and Comprehensive Cancer Center, Medical University of Vienna, A-1090 Vienna, Austria. Electronic address:

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http://dx.doi.org/10.1016/S0140-6736(15)00975-7DOI Listing
November 2015

Palbociclib for the treatment of postmenopausal breast cancer - an update.

Expert Opin Pharmacother 2016 14;17(2):255-63. Epub 2016 Jan 14.

a Department of Internal Medicine I/Division of Oncology , Medical University of Vienna , Vienna , Austria.

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http://dx.doi.org/10.1517/14656566.2016.1133590DOI Listing
June 2016

St.Gallen-2015 in Vienna: News from a successful breast cancer conference transposition!

Breast 2015 Nov 4;24 Suppl 2:S1. Epub 2015 Oct 4.

Department of Surgery, and Comprehensive Cancer Center, Medical University of Vienna, Austria; Austrian Breast and Colorectal Cancer Study Group (ABCSG), Vienna, Austria.

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https://linkinghub.elsevier.com/retrieve/pii/S09609776150016
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http://dx.doi.org/10.1016/j.breast.2015.07.030DOI Listing
November 2015

Adjuvant Bisphosphonates and Breast Cancer Survival.

Annu Rev Med 2016 28;67:1-10. Epub 2015 Aug 28.

Department of Surgery and Comprehensive Cancer Center, Medical University of Vienna, A-1090 Vienna, Austria; email:

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http://www.annualreviews.org/doi/10.1146/annurev-med-053014-
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http://dx.doi.org/10.1146/annurev-med-053014-103600DOI Listing
October 2016

Bevacizumab: no comeback in early breast cancer?

Lancet Oncol 2015 Sep 10;16(9):1001-1003. Epub 2015 Aug 10.

Department of Internal Medicine I, Breast Health Center, Comprehensive Cancer Center, Medical University of Vienna, Vienna 1090, Austria.

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http://www.thelancet.com/pdfs/journals/lanonc/PIIS1470-2045(
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http://linkinghub.elsevier.com/retrieve/pii/S147020451500124
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http://dx.doi.org/10.1016/S1470-2045(15)00124-2DOI Listing
September 2015

Targeting bone microenvironment: Clinical implications.

Authors:
Michael Gnant

Breast 2015 Nov 1;24 Suppl 2:S49-50. Epub 2015 Aug 1.

Department of Surgery, Comprehensive Cancer Center, Medical University of Vienna, A-1090 Wien, Währinger Gürtel 18-20, Austria. Electronic address:

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http://dx.doi.org/10.1016/j.breast.2015.07.012DOI Listing
November 2015

St. Gallen/Vienna 2015: A Brief Summary of the Consensus Discussion.

Breast Care (Basel) 2015 Apr;10(2):124-30

Breast Center, Department of Obstetrics and Gynecology, University of Munich, Germany.

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https://www.karger.com/Article/FullText/430488
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http://dx.doi.org/10.1159/000430488DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4464099PMC
April 2015

CDK4/6 inhibitors in luminal breast cancer.

Lancet Oncol 2015 Jan 16;16(1):2-3. Epub 2014 Dec 16.

Internal Medicine I, Breast Health Center, Comprehensive Cancer Center, Medical University of Vienna, A-1090 Vienna, Austria.

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http://dx.doi.org/10.1016/S1470-2045(14)71188-XDOI Listing
January 2015

Prediction of late distant recurrence after 5 years of endocrine treatment: a combined analysis of patients from the Austrian breast and colorectal cancer study group 8 and arimidex, tamoxifen alone or in combination randomized trials using the PAM50 risk of recurrence score.

J Clin Oncol 2015 Mar 20;33(8):916-22. Epub 2014 Oct 20.

Ivana Sestak, Jack Cuzick, Queen Mary University; Mitch Dowsett, Elena Lopez-Knowles, Royal Marsden Hospital, London, United Kingdom; Martin Filipits, Peter Dubsky, Michael Gnant, Medical University of Vienna; Christian Fesl, Austrian Breast and Colorectal Cancer Study Group, Vienna, Austria; John Wayne Cowens, Sean Ferree, NanoString Technologies, Seattle, WA; and Carl Shaper, MyRAQA, Redwood Shores, CA.

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http://dx.doi.org/10.1200/JCO.2014.55.6894DOI Listing
March 2015

Co-overexpression of HER2/HER3 is a predictor of impaired survival in breast cancer patients.

Breast 2014 Oct 10;23(5):637-43. Epub 2014 Jul 10.

Comprehensive Cancer Center Vienna, Medical University of Vienna, Austria; Department of Pathology, Medical University of Vienna, Austria.

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http://dx.doi.org/10.1016/j.breast.2014.06.011DOI Listing
October 2014

Modern therapeutic concepts of early breast cancer.

Authors:
Michael Gnant

Breast Care (Basel) 2014 May;9(2):85-6

Department of Surgery and Comprehensive Cancer Center MUW/AKH, Vienna, Austria.

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http://dx.doi.org/10.1159/000362528DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4038315PMC
May 2014

HER2-positive breast cancer: a new piece of the puzzle.

Lancet Oncol 2014 Jun 2;15(7):668-9. Epub 2014 May 2.

Department of Internal Medicine I, Breast Health Center, Comprehensive Cancer Center, Medical University of Vienna, A-1090 Vienna, Austria.

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http://dx.doi.org/10.1016/S1470-2045(14)70192-5DOI Listing
June 2014

A phase II trial of two durations of Bevacizumab added to neoadjuvant gemcitabine for borderline and locally advanced pancreatic cancer.

Anticancer Res 2014 May;34(5):2377-84

MD FACS, Department of Surgery and Comprehensive Cancer Center Medical University of Vienna, Waehringer Guertel 18-20, 1090 Vienna, Austria.

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May 2014

Follow-up after breast cancer diagnosis.

Breast Care (Basel) 2013 Dec;8(6):457-60

Department of Medicine, Harvard Medical School, Dana-Farber Cancer Institute, Boston, MA, USA.

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http://dx.doi.org/10.1159/000357586DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3919482PMC
December 2013

The PAM50 risk-of-recurrence score predicts risk for late distant recurrence after endocrine therapy in postmenopausal women with endocrine-responsive early breast cancer.

Clin Cancer Res 2014 Mar 11;20(5):1298-305. Epub 2014 Feb 11.

Authors' Affiliations: Departments of Medicine I, Pathology, and Surgery; Department of Obstetrics and Gynecology, Comprehensive Cancer Center Vienna, Medical University of Vienna; Austrian Breast and Colorectal Cancer Study Group, Vienna; Departments of Internal Medicine III and Pathology, Paracelsus Private Medical University, Salzburg; Departments of Internal Medicine and Pathology, Medical University of Graz, Graz; Departments of Pathology and Surgery, Sisters of Charity Hospital and Cancer Center, Linz; Department of Obstetrics and Gynecology, Medical University of Innsbruck, Innsbruck; Department of Surgery, General Hospital Baden, Baden, Austria; Myraqa, Redwood Shores, California; NanoString Technologies, Seattle, Washington; and British Columbia Cancer Agency, Vancouver, British Columbia, Canada.

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http://dx.doi.org/10.1158/1078-0432.CCR-13-1845DOI Listing
March 2014

Standardization of morbidity assessment in breast cancer surgery using the Clavien Dindo Classification.

Int J Surg 2014 31;12(4):334-9. Epub 2014 Jan 31.

Department of General Surgery, Medical University of Vienna, Breast Health Center, Währinger Gürtel 18-20, Vienna, Austria.

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http://dx.doi.org/10.1016/j.ijsu.2014.01.012DOI Listing
January 2015