Michael G Edwards

Michael G Edwards

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Michael G Edwards

Michael G Edwards

Publications by authors named "Michael G Edwards"

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Synthesis and Activity of a Novel Autotaxin Inhibitor-Icodextrin Conjugate.

J Med Chem 2018 09 15;61(17):7942-7951. Epub 2018 Aug 15.

School of Pharmacy and Institute for Science and Technology in Medicine , Keele University , Keele ST5 5BG , U.K.

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http://dx.doi.org/10.1021/acs.jmedchem.8b00935DOI Listing
September 2018

Temporal changes in macrophage phenotype after peripheral nerve injury.

J Neuroinflammation 2018 Jun 15;15(1):185. Epub 2018 Jun 15.

Cornell University College of Veterinary Medicine, Ithaca, NY, USA.

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http://dx.doi.org/10.1186/s12974-018-1219-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6003127PMC
June 2018

Rapid reversal of innate immune dysregulation in blood of patients and livers of humanized mice with HCV following DAA therapy.

PLoS One 2017 17;12(10):e0186213. Epub 2017 Oct 17.

Division of Gastroenterology and Hepatology, Hepatitis C Center, Department of Medicine, University of Colorado Denver (UCD), Aurora, Colorado, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0186213PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5645093PMC
October 2017

Free Fatty Acids Differentially Downregulate Chemokines in Liver Sinusoidal Endothelial Cells: Insights into Non-Alcoholic Fatty Liver Disease.

PLoS One 2016 25;11(7):e0159217. Epub 2016 Jul 25.

Department of Medicine, Division of Gastroenterology and Hepatology, University of Colorado Denver, Aurora, Colorado, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0159217PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4959750PMC
July 2017

Patient Mutation Directed shRNA Screen Uncovers Novel Bladder Tumor Growth Suppressors.

Mol Cancer Res 2015 Sep 15;13(9):1306-15. Epub 2015 Jun 15.

Departments of Surgery (Urology) and Pharmacology, University of Colorado, Aurora, Colorado. University of Colorado Comprehensive Cancer Center, Aurora, Colorado.

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http://dx.doi.org/10.1158/1541-7786.MCR-15-0130DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4573363PMC
September 2015

Novel Role for γ-Catenin in the Regulation of Cancer Cell Migration via the Induction of Hepatocyte Growth Factor Activator Inhibitor Type 1 (HAI-1).

J Biol Chem 2015 Jun 29;290(25):15610-20. Epub 2015 Apr 29.

Division of Pulmonary, Critical Care, Sleep and Allergy, Department of Medicine, University of Illinois at Chicago, Chicago, Illinois 60612, and Jesse Brown Veterans Affairs Medical Center, Chicago, Illinois 60612

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http://dx.doi.org/10.1074/jbc.M114.631820DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4505473PMC
June 2015

RhoC Is an Unexpected Target of RhoGDI2 in Prevention of Lung Colonization of Bladder Cancer.

Mol Cancer Res 2015 Mar 16;13(3):483-92. Epub 2014 Dec 16.

Department of Surgery and Pharmacology University of Colorado, Aurora, Colorado. University of Colorado Comprehensive Cancer Center, Aurora, Colorado.

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http://dx.doi.org/10.1158/1541-7786.MCR-14-0420DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4369172PMC
March 2015

Hepatitis C virus infection induces autocrine interferon signaling by human liver endothelial cells and release of exosomes, which inhibits viral replication.

Gastroenterology 2015 Feb 4;148(2):392-402.e13. Epub 2014 Nov 4.

Division of Gastroenterology and Hepatology, Hepatitis C Center, Department of Medicine, University of Colorado, Denver, Aurora, Colorado; Integrated Department in Immunology: University of Colorado Denver and National Jewish Health, Denver, Colorado; Eastern Colorado Veteran's Affairs Medical Center, Denver, Colorado. Electronic address:

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http://dx.doi.org/10.1053/j.gastro.2014.10.040DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4765499PMC
February 2015

Identification of novel gene signatures in patients with atopic dermatitis complicated by eczema herpeticum.

J Allergy Clin Immunol 2014 Oct 23;134(4):848-55. Epub 2014 Aug 23.

Department of Pediatrics, National Jewish Health, Denver, Colo; Department of Pediatrics, University of Colorado School of Medicine, Aurora, Colo. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2014.07.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4186924PMC
October 2014

FGFR1 mRNA and protein expression, not gene copy number, predict FGFR TKI sensitivity across all lung cancer histologies.

Clin Cancer Res 2014 Jun 25;20(12):3299-309. Epub 2014 Apr 25.

Authors' Affiliations: Departments of Medicine, Pathology, Craniofacial Biology, and Biostatistics and Informatics, University of Colorado Anschutz Medical Campus, Aurora, Colorado; ARIAD Pharmaceuticals, Inc., Cambridge, Massachusetts; Medical University of Gdańsk, Poland; and Department of Prostate Cancer Research, Institute of Pathology, University Hospital of Bonn, Bonn, Germany

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http://dx.doi.org/10.1158/1078-0432.CCR-13-3060DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4062100PMC
June 2014

Dendrimer Conjugate of [4-(Tetradecanoylamino)benzyl]phosphonic Acid (S32826) as an Autotaxin Inhibitor.

ACS Med Chem Lett 2014 Jan 18;5(1):34-9. Epub 2013 Nov 18.

Institute for Science & Technology in Medicine and School of Pharmacy, Keele University, Guy Hilton Research Centre , Stoke-on-Trent, Staffordshire ST4 7QB, U.K.

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http://dx.doi.org/10.1021/ml4003106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4027627PMC
January 2014

Role of IL-18 in second-hand smoke-induced emphysema.

Am J Respir Cell Mol Biol 2013 Jun;48(6):725-32

Division of Pulmonary Sciences and Critical Care Medicine, Department of Medicine, University of Colorado at Denver, Aurora, CO 80045, USA.

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http://dx.doi.org/10.1165/rcmb.2012-0173OCDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3727875PMC
June 2013

Mitogen-activated protein kinase phosphatase-1 modulates regional effects of injurious mechanical ventilation in rodent lungs.

Am J Respir Crit Care Med 2012 Jul 10;186(1):72-81. Epub 2012 May 10.

Division of Pulmonary and Critical Care Medicine, Department of Medicine, Denver Health and University of Colorado, 777 Bannock Street, Denver, CO 80204, USA.

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http://dx.doi.org/10.1164/rccm.201109-1593OCDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3400991PMC
July 2012

Promoter G-quadruplex sequences are targets for base oxidation and strand cleavage during hypoxia-induced transcription.

Free Radic Biol Med 2012 Jul 1;53(1):51-9. Epub 2012 May 1.

Department of Pharmacology and Center for Lung Biology, College of Medicine, University of South Alabama, Mobile, AL 36688, USA.

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http://dx.doi.org/10.1016/j.freeradbiomed.2012.04.024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3377816PMC
July 2012

Synthesis of the louisianin alkaloid family via a 1,2,4-triazine inverse-electron-demand Diels-Alder approach.

J Org Chem 2009 Nov;74(21):8343-54

Department of Chemistry, University of York, Heslington, York YO10 5DD, UK.

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http://dx.doi.org/10.1021/jo901761rDOI Listing
November 2009

Closed loop control of inspired oxygen concentration in trauma patients.

J Am Coll Surg 2009 May 26;208(5):763-8; discussion 768-9. Epub 2009 Mar 26.

Department of Surgery, University of Cincinnati, Cincinnati, OH 45267-0558, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S107275150900121
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http://dx.doi.org/10.1016/j.jamcollsurg.2009.01.033DOI Listing
May 2009

gem-Dimethylcyclopropanation of dibenzylideneacetone using triisopropyl sulfoxonium tetrafluoroborate.

Acta Crystallogr C 2009 Feb 10;65(Pt 2):o39-41. Epub 2009 Jan 10.

Department of Chemistry, University of York, Heslington, York YO10 5DD, England.

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http://scripts.iucr.org/cgi-bin/paper?S0108270108042431
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http://dx.doi.org/10.1107/S0108270108042431DOI Listing
February 2009

The telescoped intramolecular michael/olefination (TIMO) approach to alpha-alkylidene-gamma-butyrolactones: synthesis of (+)-paeonilactone B.

Angew Chem Int Ed Engl 2008 ;47(10):1935-7

Department of Chemistry, University of York, Heslington, York, YO10 5DD, UK.

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http://dx.doi.org/10.1002/anie.200705329DOI Listing
April 2008

A convergent synthesis of the tricyclic core of the dictyosphaeric acids.

Org Lett 2008 Jan 21;10(2):353-6. Epub 2007 Dec 21.

Department of Chemistry, University of York, Heslington, York YO10 5DD, United Kingdom.

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http://dx.doi.org/10.1021/ol702887eDOI Listing
January 2008

On the mechanism of the selenolactonization reaction with selenenyl halides.

J Org Chem 2006 Sep;71(19):7293-306

Department of Chemistry, Roger Adams Laboratory, University of Illinois, Urbana, Illinois 61801, USA.

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http://pubs.acs.org/doi/abs/10.1021/jo0610457
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http://dx.doi.org/10.1021/jo0610457DOI Listing
September 2006

Borrowing hydrogen: iridium-catalysed reactions for the formation of C-C bonds from alcohols.

Org Biomol Chem 2006 Jan 25;4(1):116-25. Epub 2005 Nov 25.

Department of Chemistry, University of Bath, Claverton Down, Bath, BA2 7AY, UK.

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http://dx.doi.org/10.1039/b511053jDOI Listing
January 2006

Impairment of the transcriptional responses to oxidative stress in the heart of aged C57BL/6 mice.

Ann N Y Acad Sci 2004 Jun;1019:85-95

Department of Genetics and Medical Genetics, University of Wisconsin, Madison, 53706, USA.

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http://dx.doi.org/10.1196/annals.1297.017DOI Listing
June 2004

Borrowing hydrogen: a catalytic route to C-C bond formation from alcohols.

Chem Commun (Camb) 2004 Jan 18(1):90-1. Epub 2003 Nov 18.

Department of Chemistry, University of Bath, Claverton Down, Bath, UKBA2 7AY.

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http://xlink.rsc.org/?DOI=B312162C
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http://dx.doi.org/10.1039/b312162cDOI Listing
January 2004

Age-related impairment of the transcriptional responses to oxidative stress in the mouse heart.

Physiol Genomics 2003 Apr 16;13(2):119-27. Epub 2003 Apr 16.

Department of Genetics and Medical Genetics, University of Wisconsin, Madison, Wisconsin 53706, USA.

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http://dx.doi.org/10.1152/physiolgenomics.00172.2002DOI Listing
April 2003

Catalytic electronic activation: indirect "Wittig" reaction of alcohols.

Angew Chem Int Ed Engl 2002 Dec;41(24):4740-3

Department of Chemistry, University of Bath, Claverton Down, Bath BA2 7AY, UK.

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http://dx.doi.org/10.1002/anie.200290034DOI Listing
December 2002