Michael F Wempe

Michael F Wempe

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Michael F Wempe

Michael F Wempe

Publications by authors named "Michael F Wempe"

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Evaluation of intravenous direct thrombin inhibitor monitoring tests: Correlation with plasma concentrations and clinical outcomes in hospitalized patients.

J Thromb Thrombolysis 2019 Sep 26. Epub 2019 Sep 26.

Department of Clinical Pharmacy, University of Colorado Skaggs School of Pharmacy and Pharmaceutical Sciences, University of Colorado Anschutz Medical Campus, 12850 E Montview Blvd, C238, Aurora, CO, 80045, USA.

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http://dx.doi.org/10.1007/s11239-019-01961-3DOI Listing
September 2019

Differential effect of grape seed extract and its active constituent procyanidin B2 3,3″-di-O-gallate against prostate cancer stem cells.

Mol Carcinog 2019 Jul 3;58(7):1105-1117. Epub 2019 Mar 3.

Department of Pharmaceutical Sciences, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of Colorado Denver-Anschutz Medical Campus, Aurora, Colorado.

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http://dx.doi.org/10.1002/mc.22995DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6548692PMC
July 2019

Developmental Pharmacokinetics and Age-Appropriate Dosing Design of Milrinone in Neonates and Infants with Acute Kidney Injury Following Cardiac Surgery.

Clin Pharmacokinet 2019 Jun;58(6):793-803

Division of Clinical Pharmacology, Cincinnati Children's Hospital Medical Center, 3333 Burnet Avenue, MLC6018, Cincinnati, OH, 45229-3039, USA.

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http://link.springer.com/10.1007/s40262-018-0729-3
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http://dx.doi.org/10.1007/s40262-018-0729-3DOI Listing
June 2019

Bitter melon juice-intake modulates glucose metabolism and lactate efflux in tumors in its efficacy against pancreatic cancer.

Carcinogenesis 2019 Jun 13. Epub 2019 Jun 13.

Department of Pharmaceutical Sciences, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of Colorado Denver-Anschutz Medical Campus, Aurora, CO, USA.

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https://academic.oup.com/carcin/advance-article/doi/10.1093/
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http://dx.doi.org/10.1093/carcin/bgz114DOI Listing
June 2019

Identification of a novel biomarker for pyridoxine-dependent epilepsy: Implications for newborn screening.

J Inherit Metab Dis 2019 May 11;42(3):565-574. Epub 2019 Mar 11.

Department of Pediatrics, Section of Clinical Genetics and Metabolism, University of Colorado School of Medicine, Aurora, Colorado.

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http://dx.doi.org/10.1002/jimd.12059DOI Listing
May 2019

Disposition of oral delta-9 tetrahydrocannabinol (THC) in children receiving cannabis extracts for epilepsy.

Clin Toxicol (Phila) 2019 May 21:1-5. Epub 2019 May 21.

a Section of Emergency Medicine and Medical Toxicology, Department of Pediatrics , University of Colorado Anschutz Medical Campus, Children's Hospital Colorado , Aurora , CO , USA.

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http://dx.doi.org/10.1080/15563650.2019.1616093DOI Listing
May 2019

Carnosine protects cardiac myocytes against lipid peroxidation products.

Amino Acids 2019 Jan 17;51(1):123-138. Epub 2018 Nov 17.

Department of Medicine, Diabetes and Obesity Center, University of Louisville, 580 South Preston Street, Delia Baxter Building, Room 421A, Louisville, KY, 40202, USA.

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http://link.springer.com/10.1007/s00726-018-2676-6
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http://dx.doi.org/10.1007/s00726-018-2676-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6377314PMC
January 2019

Bitter melon juice exerts its efficacy against pancreatic cancer via targeting both bulk and cancer stem cells.

Mol Carcinog 2018 09 18;57(9):1166-1180. Epub 2018 May 18.

Department of Pharmaceutical Sciences, Skaggs School of Pharmacy and Pharmaceutical Sciences, Aurora, Colorado.

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http://dx.doi.org/10.1002/mc.22833DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6118209PMC
September 2018

A Randomized Pharmacokinetic and Pharmacodynamic Evaluation of Every 8-Hour and 12-Hour Dosing Strategies of Vancomycin and Cefepime in Neurocritically ill Patients.

Pharmacotherapy 2018 09 20;38(9):921-934. Epub 2018 Jul 20.

Department of Clinical Pharmacy, University of Colorado Skaggs School of Pharmacy and Pharmaceutical Sciences, Aurora, Colorado.

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http://doi.wiley.com/10.1002/phar.2156
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http://dx.doi.org/10.1002/phar.2156DOI Listing
September 2018

Co-targeting intracellular pH and essential amino acid uptake cooperates to induce cell death of T-ALL/LL cells.

Leuk Lymphoma 2018 02 22;59(2):460-468. Epub 2017 Jun 22.

a Université Côte d'Azur, Inserm U1065, Team 4, Centre Méditerranéen de Médecine Moléculaire (C3M) , Nice , France.

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http://dx.doi.org/10.1080/10428194.2017.1339875DOI Listing
February 2018

JPH203, a selective L-type amino acid transporter 1 inhibitor, induces mitochondria-dependent apoptosis in Saos2 human osteosarcoma cells.

Korean J Physiol Pharmacol 2017 Nov 30;21(6):599-607. Epub 2017 Oct 30.

Department of Pharmacology, Chonnam National University Medical School, Gwangju 61469, Korea.

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http://dx.doi.org/10.4196/kjpp.2017.21.6.599DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5709476PMC
November 2017

Stability of Extemporaneously Prepared Hydroxychloroquine Sulfate 25-mg/mL Suspensions in Plastic Bottles and Syringes.

Int J Pharm Compd 2017 May-Jun;21(3):251-254

University of Colorado Skaggs School of Pharmacy and Pharmaceutical Sciences, Aurora, Colorado.

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July 2017

Antagonists of the system L neutral amino acid transporter (LAT) promote endothelial adhesivity of human red blood cells.

Thromb Haemost 2017 06 6;117(7):1402-1411. Epub 2017 Apr 6.

Tim J. McMahon, MD, PhD, Duke University Medical Center, DUMC 103003, Medical Sciences Research Building 1, 203 Research Dr., Durham, NC 27710, USA, E-mail:

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http://dx.doi.org/10.1160/TH16-05-0373DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5755361PMC
June 2017

Overlapping and Divergent Actions of Structurally Distinct Histone Deacetylase Inhibitors in Cardiac Fibroblasts.

J Pharmacol Exp Ther 2017 04 7;361(1):140-150. Epub 2017 Feb 7.

Division of Cardiology and Consortium for Fibrosis Research and Translation, Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, Colorado (K.B.S., M.S.S., W.W.B., T.A.M.); Department of Pharmaceutical Sciences, Skaggs School of Pharmacy and Pharmaceutical, Sciences, University of Colorado Denver, Aurora, Colorado (M.F.W.); Stanley Center for Psychiatric Research, Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, Massachusetts (F.F.W., E.B.H.); Department of Cancer Biology, Fox Chase Cancer Center, Philadelphia, Pennsylvania (Y.-M.K., A.J.A.); and Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Charlestown, Massachusetts (T.M.G., J.M.H.)

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http://dx.doi.org/10.1124/jpet.116.237701DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5363768PMC
April 2017

Synthesis of novel Ral inhibitors: An in vitro and in vivo study.

Bioorg Med Chem Lett 2016 12 12;26(23):5815-5818. Epub 2016 Oct 12.

Department of Pharmaceutical Sciences, University of Colorado, Aurora, CO 80045, USA. Electronic address:

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http://dx.doi.org/10.1016/j.bmcl.2016.10.021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5301652PMC
December 2016

Bronchopulmonary dysplasia impairs L-type amino acid transporter-1 expression in human and baboon lung.

Pediatr Pulmonol 2016 10 26;51(10):1048-1056. Epub 2016 Feb 26.

Department of Pediatrics, Duke University Medical Center, Durham, 27710, North Carolina.

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http://dx.doi.org/10.1002/ppul.23402DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5814304PMC
October 2016

ATM/G6PD-driven redox metabolism promotes FLT3 inhibitor resistance in acute myeloid leukemia.

Proc Natl Acad Sci U S A 2016 10 10;113(43):E6669-E6678. Epub 2016 Oct 10.

Department of Biochemistry and Molecular Genetics, University of Colorado, Aurora, CO 80045; School of Medicine, University of Colorado, Aurora, CO 80045; Integrated Department of Immunology, University of Colorado, Aurora, CO 80045; Cancer Biology Program, University of Colorado, Aurora, CO 80045; Department of Pediatrics, Section of Hematology, Oncology, and Bone Marrow Transplantation, University of Colorado, Aurora, CO 80045

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http://dx.doi.org/10.1073/pnas.1603876113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5086999PMC
October 2016

Genetic Disruption of the Multifunctional CD98/LAT1 Complex Demonstrates the Key Role of Essential Amino Acid Transport in the Control of mTORC1 and Tumor Growth.

Cancer Res 2016 08 14;76(15):4481-92. Epub 2016 Jun 14.

Medical Biology Department, Centre Scientifique de Monaco (CSM), Monaco. Institute for Research on Cancer & Aging (IRCAN), CNRS, INSERM, Centre A. Lacassagne, University of Nice-Sophia Antipolis, Nice, France.

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http://dx.doi.org/10.1158/0008-5472.CAN-15-3376DOI Listing
August 2016

Stability of dronabinol capsules when stored frozen, refrigerated, or at room temperature.

Am J Health Syst Pharm 2016 Jul;73(14):1088-92

Department of Clinical Pharmacy, University of Colorado Skaggs School of Pharmacy and Pharmaceutical Sciences, Aurora, CO.

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http://www.ajhp.org/cgi/doi/10.2146/ajhp150501
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http://dx.doi.org/10.2146/ajhp150501DOI Listing
July 2016

A WEE1 Inhibitor Analog of AZD1775 Maintains Synergy with Cisplatin and Demonstrates Reduced Single-Agent Cytotoxicity in Medulloblastoma Cells.

ACS Chem Biol 2016 Apr 8;11(4):921-30. Epub 2016 Jan 8.

Department of Pharmaceutical Sciences, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of Colorado Anschutz Medical Campus , 12850 East Montview Boulevard, V20-2102, Aurora, Colorado 80045, United States.

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http://dx.doi.org/10.1021/acschembio.5b00725DOI Listing
April 2016

Silibinin and its 2,3-dehydro-derivative inhibit basal cell carcinoma growth via suppression of mitogenic signaling and transcription factors activation.

Mol Carcinog 2016 Jan 9;55(1):3-14. Epub 2014 Dec 9.

Department of Pharmaceutical Sciences, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of Colorado Denver, Aurora, Colorado.

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http://dx.doi.org/10.1002/mc.22253DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4461565PMC
January 2016

Male rats exposed in utero to di(n-butyl) phthalate: Age-related changes in Leydig cell smooth endoplasmic reticulum and testicular testosterone-biosynthesis enzymes/proteins.

Reprod Toxicol 2016 Jan 17;59:139-46. Epub 2015 Dec 17.

Department of Toxicology, Laboratory Animal Science, Veterinary Anatomy, Animal Breeding, and Genetics, Azabu University School of Veterinary Medicine, Kanagawa, Japan; Department of Pathology, The Jikei University School of Medicine, Tokyo, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.reprotox.2015.12.001DOI Listing
January 2016

Asiatic acid induces endoplasmic reticulum stress and apoptotic death in glioblastoma multiforme cells both in vitro and in vivo.

Mol Carcinog 2015 Nov 22;54(11):1417-29. Epub 2014 Sep 22.

Department of Pharmaceutical Sciences, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of Colorado Denver, Aurora, Colorado.

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http://dx.doi.org/10.1002/mc.22220DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4369479PMC
November 2015

Procyanidin B2 3,3″-di-O-gallate inhibits endothelial cells growth and motility by targeting VEGFR2 and integrin signaling pathways.

Curr Cancer Drug Targets 2015 ;15(1):14-26

University of Colorado Denver, 12850 E. Montview Blvd, C238, Aurora, CO 80045, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4586152PMC
November 2015

Analyzing insulin samples by size-exclusion chromatography: a column degradation study.

J Pharm Sci 2015 Apr 7;104(4):1555-60. Epub 2015 Jan 7.

Department of Pharmaceutical Sciences, University of Colorado Anschutz Medical Campus, Aurora, Colorado, 80045.

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http://dx.doi.org/10.1002/jps.24330DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4359628PMC
April 2015

Promiscuous actions of small molecule inhibitors of the protein kinase D-class IIa HDAC axis in striated muscle.

FEBS Lett 2015 Apr 25;589(10):1080-8. Epub 2015 Mar 25.

Department of Medicine, Division of Cardiology, University of Colorado Denver, Aurora, CO, United States. Electronic address:

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http://dx.doi.org/10.1016/j.febslet.2015.03.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4410688PMC
April 2015

Tyrosine kinase inhibition in leukemia induces an altered metabolic state sensitive to mitochondrial perturbations.

Clin Cancer Res 2015 Mar 29;21(6):1360-72. Epub 2014 Dec 29.

Integrated Department of Immunology, University of Colorado Anschutz Medical Campus, Aurora, Colorado. School of Medicine, University of Colorado Anschutz Medical Campus, Aurora, Colorado. Department of Biochemistry and Molecular Genetics, University of Colorado Anschutz Medical Campus, Aurora, Colorado. Cancer Biology Program, University of Colorado Anschutz Medical Campus, Aurora, Colorado. Department of Pediatrics, Division of Hematology, Oncology, and Bone Marrow Transplantation, University of Colorado Anschutz Medical Campus, Aurora, Colorado. Department of Medicine, Section of Hematology, University of Colorado Anschutz Medical Campus, Aurora, Colorado.

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http://clincancerres.aacrjournals.org/content/early/2014/12/
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http://clincancerres.aacrjournals.org/content/21/6/1360.full
Web Search
http://clincancerres.aacrjournals.org/cgi/doi/10.1158/1078-0
Publisher Site
http://dx.doi.org/10.1158/1078-0432.CCR-14-2146DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4359967PMC
March 2015

Long-term storage of lyophilized liposomal formulations.

J Pharm Sci 2014 Dec 10;103(12):3869-3878. Epub 2014 Oct 10.

Department of Pharmaceutical Sciences, University of Colorado Anschutz Medical Campus, Aurora, Colorado. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00223549153028
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http://dx.doi.org/10.1002/jps.24171DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4441342PMC
December 2014

Hyperoxia inhibits nitric oxide treatment effects in alveolar epithelial cells via effects on L-type amino acid transporter-1.

Antioxid Redox Signal 2014 Nov 22;21(13):1823-36. Epub 2014 Sep 22.

1 Department of Pediatrics, Duke University Medical Center , Durham, North Carolina.

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http://dx.doi.org/10.1089/ars.2013.5664DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4202911PMC
November 2014

Discovery and characterization of small molecules that target the GTPase Ral.

Nature 2014 Nov 14;515(7527):443-7. Epub 2014 Sep 14.

1] Department of Surgery, University of Colorado, Aurora, Colorado 80045, USA [2] Department of Pharmacology, University of Colorado, Aurora, Colorado 80045, USA [3] University of Colorado Comprehensive Cancer Center, Aurora, Colorado 80045, USA.

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http://dx.doi.org/10.1038/nature13713DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4351747PMC
November 2014

Effects of in utero exposure to di(n-butyl) phthalate for estrogen receptors α, β, and androgen receptor of Leydig cell on rats.

Toxicol Pathol 2014 Jul 25;42(5):877-87. Epub 2013 Sep 25.

Department of Toxicology, Laboratory Animal Science and Veterinary Anatomy, Azabu University School of Veterinary Medicine, Kanagawa, Japan.

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http://dx.doi.org/10.1177/0192623313502879DOI Listing
July 2014

Weight-based versus set dosing of vancomycin for coronary artery bypass grafting or aortic valve surgery.

J Thorac Cardiovasc Surg 2014 Jun 15;147(6):1925-30. Epub 2014 Jan 15.

Division of Cardiothoracic Surgery, Department of Surgery, University of Colorado Anschutz Medical Center, Aurora, Colo.

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http://dx.doi.org/10.1016/j.jtcvs.2013.12.037DOI Listing
June 2014

Atypical Leydig cell hyperplasia in adult rats with low T and high LH induced by prenatal Di(n-butyl) phthalate exposure.

Toxicol Pathol 2013 11;41(3):480-6. Epub 2012 Sep 11.

Department of Toxicology and Laboratory Animal Science, Azabu University School of Veterinary Medicine, Kanagawa, Japan.

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http://dx.doi.org/10.1177/0192623312457272DOI Listing
February 2014

Nuclear Morphometric Analysis of Leydig Cells of Male Pubertal Rats Exposed In Utero to Di(n-butyl) Phthalate.

J Toxicol Pathol 2013 Dec 26;26(4):439-46. Epub 2013 Dec 26.

Department of Toxicology, Laboratory Animal Science, and Veterinary Anatomy, Azabu University School of Veterinary Medicine, 1-17-71 Chuo, Sagamihara, Kanagawa 252-5201, Japan.

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http://dx.doi.org/10.1293/tox.2013-0031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3921929PMC
December 2013

Influence of CYP2C8*2 on the pharmacokinetics of pioglitazone in healthy African-American volunteers.

Pharmacotherapy 2013 Sep 26;33(9):1000-7. Epub 2013 May 26.

Department of Pharmaceutical Sciences, University of Colorado Skaggs School of Pharmacy and Pharmaceutical Sciences, Aurora, Colorado.

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http://dx.doi.org/10.1002/phar.1292DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3760990PMC
September 2013

Investigation of the role of transporters on the hepatic elimination of an LAT1 selective inhibitor JPH203.

J Pharm Sci 2013 Sep 27;102(9):3228-38. Epub 2013 May 27.

Laboratory of Molecular Pharmacokinetics, Graduate School of Pharmaceutical Sciences, The University of Tokyo, Bunkyo-ku, Tokyo 113-0033, Japan.

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http://dx.doi.org/10.1002/jps.23601DOI Listing
September 2013

Human organic cation transporter 2 (hOCT2): Inhibitor studies using S2-hOCT2 cells.

Toxicology 2013 Aug 13;310:98-103. Epub 2013 Jun 13.

Department of Legal Medicine, St. Marianna University School of Medicine, 2-16-1 Sugao, Miyamae-ku, Kawasaki 216-8511, Japan.

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http://dx.doi.org/10.1016/j.tox.2013.06.001DOI Listing
August 2013

Stability of dexmedetomidine in polyvinyl chloride bags containing 0.9% sodium chloride injection.

Am J Health Syst Pharm 2013 Aug;70(15):1336-41

Surgical Intensive Care Unit, Denver Health Medical Center, Denver, CO, USA.

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http://dx.doi.org/10.2146/ajhp120390DOI Listing
August 2013

Effect of ABCB1 polymorphisms and atorvastatin on sitagliptin pharmacokinetics in healthy volunteers.

Eur J Clin Pharmacol 2013 Jul 14;69(7):1401-9. Epub 2013 Feb 14.

Department of Pharmaceutical Sciences, University of Colorado Skaggs School of Pharmacy and Pharmaceutical Sciences, 12850 East Montview Boulevard, Mail Stop C238, Aurora, CO 80045, USA.

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http://dx.doi.org/10.1007/s00228-013-1475-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3676426PMC
July 2013

Bitter melon juice activates cellular energy sensor AMP-activated protein kinase causing apoptotic death of human pancreatic carcinoma cells.

Carcinogenesis 2013 Jul 8;34(7):1585-92. Epub 2013 Mar 8.

Department of Pharmaceutical Sciences, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of Colorado Cancer Center, University of Colorado, Aurora, CO 80045, USA.

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https://academic.oup.com/carcin/article-lookup/doi/10.1093/c
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http://dx.doi.org/10.1093/carcin/bgt081DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3697895PMC
July 2013

Signal-dependent repression of DUSP5 by class I HDACs controls nuclear ERK activity and cardiomyocyte hypertrophy.

Proc Natl Acad Sci U S A 2013 Jun 29;110(24):9806-11. Epub 2013 May 29.

Division of Cardiology, Department of Medicine, University of Colorado Denver, Aurora, CO 80045, USA.

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http://dx.doi.org/10.1073/pnas.1301509110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3683796PMC
June 2013

Potent human uric acid transporter 1 inhibitors: in vitro and in vivo metabolism and pharmacokinetic studies.

Drug Des Devel Ther 2012 8;6:323-39. Epub 2012 Nov 8.

Department of Pharmaceutical Sciences, School of Pharmacy, University of Colorado Denver, Anschutz Medical Campus, Aurora, CO 80045, USA.

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http://dx.doi.org/10.2147/DDDT.S35805DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3496402PMC
April 2013

Metabolism and pharmacokinetic studies of JPH203, an L-amino acid transporter 1 (LAT1) selective compound.

Drug Metab Pharmacokinet 2012 13;27(1):155-61. Epub 2011 Sep 13.

School of Pharmacy, University of Colorado Denver, Anschutz Medical Campus, Aurora, CO 80045, USA.

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July 2012

New insights into the structure of (1→3,1→6)-β-D-glucan side chains in the Candida glabrata cell wall.

PLoS One 2011 11;6(11):e27614. Epub 2011 Nov 11.

Department of Surgery, Quillen College of Medicine, East Tennessee State University, Johnson City, Tennessee, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0027614PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3214063PMC
April 2012

Glucuronidation and methylation of procyanidin dimers b2 and 3,3″-di-o-galloyl-b2 and corresponding monomers epicatechin and 3-o-galloyl-epicatechin in mouse liver.

Pharm Res 2012 Mar 9;29(3):856-65. Epub 2011 Nov 9.

Department of Pharmaceutical Sciences, School of Pharmacy, University of Colorado Denver, Anschutz Medical Campus, MS C238, 12850 E. Montview Blvd., Aurora, Colorado, 80045, USA.

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http://dx.doi.org/10.1007/s11095-011-0614-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3288310PMC
March 2012

Sex-associated difference in estrogen receptor β expression in N-methyl-N'-nitro-N-nitrosoguanidine-induced gastric cancers in rats.

Comp Med 2011 Oct;61(5):412-8

Department of Toxicology and Biochemistry, Azabu University School of Veterinary Medicine, Kanagawa, Japan; Department of Pathology, The Jikei University School of Medicine, Tokyo, Japan.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3193063PMC
October 2011

Developing potent human uric acid transporter 1 (hURAT1) inhibitors.

J Med Chem 2011 Apr 30;54(8):2701-13. Epub 2011 Mar 30.

School of Pharmacy, University of Colorado Anschutz Medical Campus, Aurora, Colorado 80045, United States.

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http://dx.doi.org/10.1021/jm1015022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3124071PMC
April 2011

The effect of cholesterol domains on PEGylated liposomal gene delivery in vitro.

Ther Deliv 2011 Apr;2(4):451-60

School of Pharmacy, University of Colorado Denver, 12850 E Montview Blvd, Aurora, CO 80045, USA.

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http://dx.doi.org/10.4155/tde.11.13DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3303184PMC
April 2011

Atazanavir metabolism according to CYP3A5 status: an in vitro-in vivo assessment.

Drug Metab Dispos 2011 Mar 9;39(3):522-7. Epub 2010 Dec 9.

Department of Pharmaceutical Sciences, University of Colorado Denver, Aurora, Colorado 80045, USA.

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http://dmd.aspetjournals.org/cgi/doi/10.1124/dmd.110.036178
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http://dx.doi.org/10.1124/dmd.110.036178DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3061561PMC
March 2011

The hydroxyl functional group of N-(4-hydroxyphenyl)retinamide mediates cellular uptake and cytotoxicity in premalignant and malignant human epithelial cells.

Free Radic Biol Med 2010 Dec 23;49(12):2001-9. Epub 2010 Oct 23.

Department of Pharmaceutical Sciences, University of Colorado School of Pharmacy, Aurora, CO 80045, USA.

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http://dx.doi.org/10.1016/j.freeradbiomed.2010.09.032DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3005946PMC
December 2010

Identification of a novel organic anion transporter mediating carnitine transport in mouse liver and kidney.

Cell Physiol Biochem 2010 23;25(4-5):511-22. Epub 2010 Mar 23.

Department of Pharmacology and Toxicology, Kyorin University School of Medicine, Tokyo, Japan.

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http://dx.doi.org/10.1159/000303060DOI Listing
June 2010

Xenopus laevis oocytes expressing human P-glycoprotein: probing trans- and cis-inhibitory effects on [3H]vinblastine and [3H]digoxin efflux.

Pharmacol Res 2010 Jan 21;61(1):76-84. Epub 2009 Jul 21.

Kobuchisawa Research Laboratories, Fuji Biomedix Co., Ltd., Hokuto-shi, Yamanashi, Japan.

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http://dx.doi.org/10.1016/j.phrs.2009.07.002DOI Listing
January 2010

Investigating idebenone and idebenone linoleate metabolism: in vitro pig ear and mouse melanocyte studies.

J Cosmet Dermatol 2009 Mar;8(1):63-73

Department of Pharmacology, East Tennessee State University, Johnson City, TN 37614-1708, USA.

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http://dx.doi.org/10.1111/j.1473-2165.2009.00426.xDOI Listing
March 2009

Improving glyburide solubility and dissolution by complexation with hydroxybutenyl-beta-cyclodextrin.

J Pharm Pharmacol 2009 Jan;61(1):23-30

Goethe University, Institute of Pharmaceutical Technology, Frankfurt/Main, Germany.

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http://dx.doi.org/10.1211/jpp/61.01.0004DOI Listing
January 2009

Establishment and characterization of mammalian cell lines stably expressing human L-type amino acid transporters.

J Pharmacol Sci 2008 Dec 10;108(4):505-16. Epub 2008 Dec 10.

Department of Pharmacology and Toxicology, Kyorin University School of Medicine, Japan.

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http://dx.doi.org/10.1254/jphs.08232fpDOI Listing
December 2008

Pharmacokinetics of saquinavir after intravenous and oral dosing of saquinavir: hydroxybutenyl-beta-cyclodextrin formulations.

Biomacromolecules 2008 Jan 12;9(1):305-13. Epub 2007 Dec 12.

Eastman Chemical Company, Research Laboratories, P.O. Box 1972, Kingsport, Tennessee 37662, USA.

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http://dx.doi.org/10.1021/bm700827hDOI Listing
January 2008

Pharmacokinetics of itraconazole after intravenous and oral dosing of itraconazole-cyclodextrin formulations.

J Pharm Sci 2007 Nov;96(11):3100-16

Eastman Chemical Company, Research Laboratories, PO Box 1972, Kingsport, Tennessee 37662, USA.

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http://dx.doi.org/10.1002/jps.20878DOI Listing
November 2007

Mechanism of inhibition of P-glycoprotein mediated efflux by vitamin E TPGS: influence on ATPase activity and membrane fluidity.

Mol Pharm 2007 May-Jun;4(3):465-74. Epub 2007 Mar 17.

Biopharmaceutics and Pharmaceutical Technology, Saarland University, 66123 Saarbrücken, Germany, Eastman Chemical Company.

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http://pubs.acs.org/doi/abs/10.1021/mp060121r
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http://dx.doi.org/10.1021/mp060121rDOI Listing
August 2007

Pharmacokinetics of tamoxifen after intravenous and oral dosing of tamoxifen-hydroxybutenyl-beta-cyclodextrin formulations.

J Pharm Sci 2007 Mar;96(3):644-60

Eastman Chemical Company, Research Laboratories, P.O. Box 1972, Kingsport, Tennessee 37662, USA.

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http://dx.doi.org/10.1002/jps.20709DOI Listing
March 2007

Solubilization and dissolution of tamoxifen-hydroxybutenyl cyclodextrin complexes.

J Pharm Sci 2006 Oct;95(10):2246-55

Research Laboratories, Eastman Chemical Company, P.O. Box 1972, Kingsport, Tennessee 37662, USA.

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http://dx.doi.org/10.1002/jps.20710DOI Listing
October 2006

Liquid chromatography-mass spectrometry/mass spectrometry method development for drug metabolism studies: Examining lipid matrix ionization effects in plasma.

J Chromatogr B Analyt Technol Biomed Life Sci 2006 Apr 23;833(2):219-30. Epub 2006 Feb 23.

Eastman Chemical Company, Building 150 Kingsport, TN 37662-5150, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S157002320600098
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http://dx.doi.org/10.1016/j.jchromb.2006.02.011DOI Listing
April 2006

Influence of vitamin E TPGS poly(ethylene glycol) chain length on apical efflux transporters in Caco-2 cell monolayers.

J Control Release 2006 Mar 10;111(1-2):35-40. Epub 2006 Jan 10.

Department of Biopharmaceutics and Pharmaceutical Technology, Saarland University, 66123 Saarbruecken, Germany.

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http://dx.doi.org/10.1016/j.jconrel.2005.11.005DOI Listing
March 2006

Molecular identification of a novel carnitine transporter specific to human testis. Insights into the mechanism of carnitine recognition.

J Biol Chem 2002 Sep 27;277(39):36262-71. Epub 2002 Jun 27.

Department of Pharmacology and Toxicology, Kyorin University, School of Medicine, 6-20-2 Shinkawa, Mitaka, Tokyo 181-8611, Japan.

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http://dx.doi.org/10.1074/jbc.M203883200DOI Listing
September 2002