Michael F McDermott

Michael F McDermott

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Michael F McDermott

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TNF receptor signalling in autoinflammatory diseases.

Int Immunol 2019 Sep;31(10):639-648

Leeds Institute of Rheumatic and Musculoskeletal Medicine (LIRMM), Wellcome Trust Brenner Building, University of Leeds, Leeds, UK.

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http://dx.doi.org/10.1093/intimm/dxz024DOI Listing
September 2019

ENaC-mediated sodium influx exacerbates NLRP3-dependent inflammation in cystic fibrosis.

Elife 2019 09 18;8. Epub 2019 Sep 18.

Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, United Kingdom.

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http://dx.doi.org/10.7554/eLife.49248DOI Listing
September 2019

ER Stress: A Therapeutic Target in Rheumatoid Arthritis?

Trends Pharmacol Sci 2018 07 23;39(7):610-623. Epub 2018 Apr 23.

Leeds Institute of Rheumatic and Musculoskeletal Medicine (LIRMM), Wellcome Trust Brenner Building, St James's University Hospital, Beckett Street, Leeds LS9 7TF, UK. Electronic address:

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http://dx.doi.org/10.1016/j.tips.2018.03.010DOI Listing
July 2018

Autoinflammatory disease in the lung.

Immunology 2018 Apr 19. Epub 2018 Apr 19.

Cystic Fibrosis Trust Strategic Research Centre, St James's University Hospital, Leeds, UK.

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http://doi.wiley.com/10.1111/imm.12937
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http://dx.doi.org/10.1111/imm.12937DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6050210PMC
April 2018

Effects of microRNA-146a on the proliferation and apoptosis of human osteochondrocytes by targeting TRAF6 through the NF- κB signalling pathway.

Biosci Rep 2017 08 12;37(4). Epub 2017 Jul 12.

Leeds Institute of Rheumatic and Musculoskeletal Medicine (LIRMM), Wellcome Trust Brenner Building, St James University Hospital, University of Leeds, Leeds 32840, U.K.

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http://bioscirep.org/lookup/doi/10.1042/BSR20170180
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http://dx.doi.org/10.1042/BSR20170180DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5518530PMC
August 2017

Lessons from characterization and treatment of the autoinflammatory syndromes.

Curr Opin Rheumatol 2017 03;29(2):187-194

aInflammatory Disease Section, National Human Genome Research Institute, Bethesda, Maryland, USA bNIHR National Institute for Health Research-Leeds Musculoskeletal Biomedical Research Unit (NIHR-LMBRU) and Leeds Institute of Rheumatic and Musculoskeletal Medicine (LIRMM), Wellcome Trust Brenner Building, St. James's University Hospital, Leeds, UK.

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http://dx.doi.org/10.1097/BOR.0000000000000362DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5823535PMC
March 2017

Autoinflammatory diseases: update on classification diagnosis and management.

J Clin Pathol 2017 Jan 19;70(1):1-8. Epub 2016 Sep 19.

National Institute for Health Research-Leeds Musculoskeletal Biomedical Research Unit (NIHR-LMBRU), Leeds Institute of Rheumatic and Musculoskeletal Medicine (LIRMM), Wellcome Trust Brenner Building, St James's University Hospital, Leeds, UK.

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http://jcp.bmj.com/lookup/doi/10.1136/jclinpath-2016-203810
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http://dx.doi.org/10.1136/jclinpath-2016-203810DOI Listing
January 2017

The burgeoning field of innate immune-mediated disease and autoinflammation.

J Pathol 2017 Jan 11;241(2):123-139. Epub 2016 Nov 11.

National Institute for Health Research-Leeds Musculoskeletal Biomedical Research Unit (NIHR-LMBRU) and Leeds Institute of Rheumatic and Musculoskeletal Medicine (LIRMM), Wellcome Trust Brenner Building, St James's University Hospital, Leeds, UK.

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http://dx.doi.org/10.1002/path.4812DOI Listing
January 2017

Protection against lupus-like inflammatory disease is in the LAP of non-canonical autophagy.

Ann Transl Med 2016 Dec;4(24):513

National Institute for Health Research-Leeds Musculoskeletal Biomedical Research Unit (NIHR-LMBRU) and Leeds Institute of Rheumatic and Musculoskeletal Medicine (LIRMM), Wellcome Trust Brenner Building, St James's University Hospital, Leeds, UK.

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http://dx.doi.org/10.21037/atm.2016.12.30DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5233484PMC
December 2016

Anakinra as a diagnostic challenge and treatment option for systemic autoinflammatory disorders of undefined etiology.

JCI Insight 2016 05 5;1(6):e86336. Epub 2016 May 5.

NIH Research-Leeds Musculoskeletal Biomedical Research Unit (NIHR-LMBRU) and Leeds Institute of Rheumatic and Musculoskeletal Medicine (LIRMM), Wellcome Trust Brenner Building, St. James's University Hospital, Beckett Street, Leeds, United Kingdom.

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https://insight.jci.org/articles/view/86336
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http://dx.doi.org/10.1172/jci.insight.86336DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5033915PMC
May 2016

Protein misfolding and dysregulated protein homeostasis in autoinflammatory diseases and beyond.

Semin Immunopathol 2015 Jul 21;37(4):335-47. Epub 2015 May 21.

Immunoregulation Section, Autoimmunity Branch, National Institute of Arthritis, Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD, 20892, USA.

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http://dx.doi.org/10.1007/s00281-015-0496-2DOI Listing
July 2015

Clinical genetics in 2014: New monogenic diseases span the immunological disease continuum.

Nat Rev Rheumatol 2015 Feb 23;11(2):67-8. Epub 2014 Dec 23.

National Institute for Health Research-Leeds Musculoskeletal Biomedical Research Unit (NIHR-LMBRU), Leeds Institute of Rheumatic and Musculoskeletal Medicine (LIRMM), Wellcome Trust Brenner Building, St James University, Beckett Street, Leeds LS9 7TF, UK.

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http://dx.doi.org/10.1038/nrrheum.2014.215DOI Listing
February 2015

TNF and TNF-receptors: From mediators of cell death and inflammation to therapeutic giants - past, present and future.

Cytokine Growth Factor Rev 2014 Aug 1;25(4):453-72. Epub 2014 Aug 1.

Experimental Rheumatology, National Institute for Health Research - Leeds Musculoskeletal Biomedical Research Unit (NIHR-LMBRU), and Leeds Institute of Rheumatic and Musculoskeletal Medicine (LIRMM), Wellcome Trust Brenner Building, St James University, Beckett Street, West Yorkshire, Leeds LS9 7TF, UK. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S13596101140007
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http://dx.doi.org/10.1016/j.cytogfr.2014.07.016DOI Listing
August 2014

TLR dependent XBP-1 activation induces an autocrine loop in rheumatoid arthritis synoviocytes.

J Autoimmun 2014 May 31;50:59-66. Epub 2013 Dec 31.

NIHR-Leeds Musculoskeletal Biomedical Research Unit (NIHR-LMBRU), Leeds Institute of Rheumatic and Musculoskeletal Medicine (LIRMM), Wellcome Trust Brenner Building, St James's University Hospital, Beckett Street, Leeds LS9 7TF, UK. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S08968411130014
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http://dx.doi.org/10.1016/j.jaut.2013.11.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4012140PMC
May 2014

IL-17A RNA aptamer: possible therapeutic potential in some cells, more than we bargained for in others?

J Invest Dermatol 2014 Mar 20;134(3):852-855. Epub 2013 Sep 20.

Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, UK; Centre for Skin Sciences, School of Life Sciences, University of Bradford, Bradford, UK; Department of Dermatology, St Luke's Hospital, Bradford Teaching Hospitals NHS Foundation Trust, Bradford, UK; Chapel Allerton Hospital, Leeds Musculoskeletal Biomedical Research Unit, National Institute for Health Research, Leeds, UK. Electronic address:

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http://dx.doi.org/10.1038/jid.2013.399DOI Listing
March 2014

Identification of a new exon 2-skipped TNFR1 transcript: regulation by three functional polymorphisms of the TNFR-associated periodic syndrome (TRAPS) gene.

Ann Rheum Dis 2014 Jan 16;73(1):290-7. Epub 2013 Mar 16.

Génétique des maladies Autoinflammatoires et des ostéoarthropathies chroniques, INSERM U844, Hôpital Saint Eloi, Bâtiment INM, , Montpellier, France.

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http://dx.doi.org/10.1136/annrheumdis-2012-203023DOI Listing
January 2014

Involvement of X-box binding protein 1 and reactive oxygen species pathways in the pathogenesis of tumour necrosis factor receptor-associated periodic syndrome.

Ann Rheum Dis 2012 Dec 7;71(12):2035-43. Epub 2012 Jun 7.

Experimental Rheumatology, National Institute for Health Research–Leeds Musculoskeletal Biomedical Research Unit, Leeds Institute of Molecular Medicine, Leeds, West Yorkshire, UK.

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http://dx.doi.org/10.1136/annrheumdis-2011-201197DOI Listing
December 2012

Autoinflammatory syndromes and cellular responses to stress: pathophysiology, diagnosis and new treatment perspectives.

Best Pract Res Clin Rheumatol 2012 Aug;26(4):505-33

Department of Clinical Immunology, St. James's University Hospital, Leeds, UK.

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https://linkinghub.elsevier.com/retrieve/pii/S15216942120007
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http://dx.doi.org/10.1016/j.berh.2012.07.009DOI Listing
August 2012

Anti-TNF treatment in rheumatoid arthritis.

Curr Pharm Des 2011 ;17(29):3141-54

NIHR-Leeds Musculoskeletal Biomedical Research Unit, University of Leeds, Leeds, LS9 7TF, United Kingdom, UK.

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http://dx.doi.org/10.2174/138161211798157658DOI Listing
March 2012

Familial Mediterranean fever and related periodic fever syndromes/autoinflammatory diseases.

Curr Opin Rheumatol 2012 Jan;24(1):103-12

Department of Clinical Immunology, NIHR-Leeds Musculoskeletal Biomedical Research Unit (NIHR-LMBRU), Leeds Institute of Molecular Medicine, St. James's University Hospital, Leeds, UK.

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http://dx.doi.org/10.1097/BOR.0b013e32834dd2d5DOI Listing
January 2012

Rilonacept in the management of cryopyrin-associated periodic syndromes (CAPS).

J Inflamm Res 2010 19;3:1-8. Epub 2010 Jan 19.

NIHR-Leeds Musculoskeletal Biomedical Research Unit (NIHR-LMBRU), Leeds Institute of Molecular Medicine (LIMM), St. James's University Hospital, Leeds, UK.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3218731PMC
November 2011

The role of the NLRP3 inflammasome in gout.

J Inflamm Res 2011 13;4:39-49. Epub 2011 Mar 13.

Section of Musculoskeletal Disease, Leeds Institute of Molecular Medicine, University of Leeds, Leeds, UK.

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http://www.dovepress.com/the-role-of-the-nlrp3-inflammasome-
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http://dx.doi.org/10.2147/JIR.S11330DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3218743PMC
November 2011

Is caspase 1 central to activation of interleukin-1?

Joint Bone Spine 2011 Jul 3;78(4):327-30. Epub 2011 Apr 3.

Institute of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds, UK.

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http://dx.doi.org/10.1016/j.jbspin.2011.02.004DOI Listing
July 2011

Lessons from anti-TNF biologics: infliximab failure in a TRAPS family with the T50M mutation in TNFRSF1A.

Adv Exp Med Biol 2011 ;691:409-19

Centre for Diabetes, Blizard Institute of Cell and Molecular Science, Barts and The London School of Medicine and Dentistry, Whitechapel, London E1 2AT, UK.

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http://link.springer.com/10.1007/978-1-4419-6612-4_43
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http://dx.doi.org/10.1007/978-1-4419-6612-4_43DOI Listing
April 2011

Inflammasomes and autoimmunity.

Trends Mol Med 2011 Feb 14;17(2):57-64. Epub 2010 Dec 14.

Department of Immunology, St. Jude Children's Research Hospital, MS #351, Suite E7004, 262 Danny Thomas Place, Memphis, TN 38105, USA.

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http://dx.doi.org/10.1016/j.molmed.2010.11.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3057120PMC
February 2011

Genetic variants within the MAP kinase signalling network and anti-TNF treatment response in rheumatoid arthritis patients.

Ann Rheum Dis 2011 Jan 30;70(1):98-103. Epub 2010 Aug 30.

NIHR-Leeds Musculoskeletal Biomedical Research Unit (NIHR-LMBRU), University of Leeds, Leeds, UK.

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http://dx.doi.org/10.1136/ard.2010.133249DOI Listing
January 2011

Gevokizumab, an anti-IL-1β mAb for the potential treatment of type 1 and 2 diabetes, rheumatoid arthritis and cardiovascular disease.

Curr Opin Mol Ther 2010 Dec;12(6):755-69

NIHR-Leeds Musculoskeletal Biomedical Research Unit, Leeds Institute of Molecular Medicine, Wellcome Trust Brenner Building, St. James's University Hospital, Beckett Street, Leeds LS9 7TF, UK.

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December 2010

Canakinumab: a human anti-IL-1β monoclonal antibody for the treatment of cryopyrin-associated periodic syndromes.

Expert Rev Clin Immunol 2010 Nov;6(6):831-41

Rheumatology Research Group, School of Immunity and Infection, College of Medical and Dental Sciences, University of Birmingham, Edgbaston, B15 2TT, UK.

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http://www.tandfonline.com/doi/full/10.1586/eci.10.66
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http://dx.doi.org/10.1586/eci.10.66DOI Listing
November 2010

Vitamin D3 down-regulates intracellular Toll-like receptor 9 expression and Toll-like receptor 9-induced IL-6 production in human monocytes.

Rheumatology (Oxford) 2010 Aug 30;49(8):1466-71. Epub 2010 Apr 30.

NIHR-Leeds Musculoskeletal Biomedical Research Unit, Leeds Institute of Molecular Medicine, Wellcome Trust Brenner Building, St James's University Hospital, Beckett Street, Leeds LS9 7TF, UK.

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https://academic.oup.com/rheumatology/article-lookup/doi/10.
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http://dx.doi.org/10.1093/rheumatology/keq124DOI Listing
August 2010

The NLRP3 inflammasome, a target for therapy in diverse disease states.

Eur J Immunol 2010 Mar;40(3):631-4

Section of Oncology and Clinical Research, Leeds Institute of Molecular Medicine, Leeds, UK.

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http://dx.doi.org/10.1002/eji.200940162DOI Listing
March 2010

Periodic fever syndrome and autoinflammatory diseases.

F1000 Med Rep 2010 Jan 18;2. Epub 2010 Jan 18.

NIHR-Leeds Musculoskeletal Biomedical Research Unit (NIHR-LMBRU), Leeds Institute of Molecular Medicine, Wellcome Trust Brenner Building, St. James's University Hospital Leeds, LS9 7TF UK.

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http://dx.doi.org/10.3410/M2-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2948378PMC
January 2010

Inflammation: canakinumab for the cryopyrin-associated periodic syndromes.

Nat Rev Rheumatol 2009 Oct;5(10):529-30

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http://dx.doi.org/10.1038/nrrheum.2009.195DOI Listing
October 2009

NOD-like receptors and inflammation.

Arthritis Res Ther 2008 25;10(6):228. Epub 2008 Nov 25.

Section of Musculoskeletal Disease, Leeds Institute of Molecular Medicine, St James's University Hospital, Leeds, UK.

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http://arthritis-research.biomedcentral.com/articles/10.1186
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http://dx.doi.org/10.1186/ar2525DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2656221PMC
August 2009

p38(MAPK): stress responses from molecular mechanisms to therapeutics.

Trends Mol Med 2009 Aug 6;15(8):369-79. Epub 2009 Aug 6.

NIHR - Leeds Musculoskeletal Biomedical Research Unit, St James's University Hospital, Leeds, LS9 7TF, UK.

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http://dx.doi.org/10.1016/j.molmed.2009.06.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3016890PMC
August 2009

Proteolytic activation of the cytotoxic phenotype during human NK cell development.

J Immunol 2009 Jul 1;183(2):803-13. Epub 2009 Jul 1.

Leeds Institute of Molecular Medicine, Wellcome Trust Brenner Building, University of Leeds, St. James's University Hospital, Leeds, United Kingdom.

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http://dx.doi.org/10.4049/jimmunol.0713829DOI Listing
July 2009

Rilonacept in the treatment of chronic inflammatory disorders.

Drugs Today (Barc) 2009 Jun;45(6):423-30

NIHR-Leeds Musculoskeletal Biomedical Research Unit, Leeds Institute of Molecular Medicine, St. James's University Hospital, Leeds, UK.

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http://journals.prous.com/journals/servlet/xmlxsl/pk_journal
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http://dx.doi.org/10.1358/dot.2009.45.6.1378935DOI Listing
June 2009

An integrated classification of pediatric inflammatory diseases, based on the concepts of autoinflammation and the immunological disease continuum.

Pediatr Res 2009 May;65(5 Pt 2):38R-45R

NIHR-Leeds Molecular Biology Research Unit (NIHR-LMBRU), University of Leeds, Leeds LS9 7TF, United Kingdom.

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http://dx.doi.org/10.1203/PDR.0b013e31819dbd0aDOI Listing
May 2009

Canakinumab, a fully-human mAb against IL-1beta for the potential treatment of inflammatory disorders.

Curr Opin Mol Ther 2009 Feb;11(1):81-9

Section of Musculoskeletal Disease, Leeds Institute of Molecular Medicine, Wellcome Trust Brenner Building, St James's University Hospital, Leeds, LS9 7TF, UK.

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February 2009

Proinflammatory action of the antiinflammatory drug infliximab in tumor necrosis factor receptor-associated periodic syndrome.

Arthritis Rheum 2009 Feb;60(2):619-25

Institute of Cell and Molecular Science, Barts and The London School of Medicine and Dentistry, London, UK.

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http://doi.wiley.com/10.1002/art.24294
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http://dx.doi.org/10.1002/art.24294DOI Listing
February 2009

Rilonacept in cryopyrin-associated periodic syndromes: the beginning of longer-acting interleukin-1 antagonism.

Nat Clin Pract Rheumatol 2009 Jan 18;5(1):14-5. Epub 2008 Nov 18.

Department of Rheumatology, Division of Immunity, Infection and Inflammation, Institute for Biomedical Research, University of Birmingham, Birmingham, UK.

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http://www.nature.com/articles/ncprheum0959
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http://dx.doi.org/10.1038/ncprheum0959DOI Listing
January 2009

Tumor necrosis factor receptor-associated periodic syndrome (TRAPS) or familial Hibernian fever: presentation in a four-day-old infant.

J Clin Rheumatol 2008 Dec;14(6):342-5

Academic Department of Paediatrics, National University of Ireland, Galway, Ireland.

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http://dx.doi.org/10.1097/RHU.0b013e31817d109bDOI Listing
December 2008

Long term management of patients with cryopyrin-associated periodic syndromes (CAPS): focus on rilonacept (IL-1 Trap).

Biologics 2008 Dec;2(4):733-42

Department of Rheumatology, Division of Immunity, Infection and Inflammation, Institute for Biomedical Research, The University of Birmingham, Birmingham, UK.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2727888PMC
December 2008

Fifth International Congress on Familial Mediterranean Fever and Systemic Autoinflammatory Diseases.

Expert Rev Clin Immunol 2008 Jul;4(4):425-8

CHU Montpellier, Unité Médicale des Maladies Auto-Inflammatoires, Hôpital Arnaud de Villeneuve, Montpellier, F-34295, France.

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http://dx.doi.org/10.1586/1744666X.4.4.425DOI Listing
July 2008

Use of anakinra (Kineret) in the treatment of familial cold autoinflammatory syndrome with a 16-month follow-up.

J Cutan Med Surg 2008 Jan-Feb;12(1):8-16

Division of Dermatology and Department of Medicine, Dalhousie University, Halifax, NS, Canada.

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http://dx.doi.org/10.2310/7750.2008.07050DOI Listing
May 2008

The asthma emergency department visit: treating a crisis in the midst of uncontrolled disease.

Ann Allergy Asthma Immunol 2008 Mar;100(3):237-43

Section of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Rush University Medical Center, Chicago, Illinois 60612, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S108112061060448
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http://dx.doi.org/10.1016/S1081-1206(10)60448-6DOI Listing
March 2008

Successful treatment of resistant pseudogout with anakinra.

Arthritis Rheum 2008 Feb;58(2):631-3

Calderdale Royal Hospital, Halifax, UK.

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http://dx.doi.org/10.1002/art.23119DOI Listing
February 2008

Primer: inflammasomes and interleukin 1beta in inflammatory disorders.

Nat Clin Pract Rheumatol 2008 Jan;4(1):34-42

Leeds Institute of Molecular Medicine, St James's University Hospital, Leeds, UK.

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http://www.nature.com/articles/ncprheum0681
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http://dx.doi.org/10.1038/ncprheum0681DOI Listing
January 2008

The NLR network and the immunological disease continuum of adaptive and innate immune-mediated inflammation against self.

Semin Immunopathol 2007 Sep 6;29(3):303-13. Epub 2007 Sep 6.

The Leeds Institute of Molecular Medicine, Wellcome Trust Brenner Building, St James's University Hospital, The University of Leeds, Leeds, UK.

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http://link.springer.com/10.1007/s00281-007-0084-1
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http://dx.doi.org/10.1007/s00281-007-0084-1DOI Listing
September 2007

From inflammasomes to fevers, crystals and hypertension: how basic research explains inflammatory diseases.

Trends Mol Med 2007 Sep 5;13(9):381-8. Epub 2007 Sep 5.

Leeds Institute of Molecular Medicine, St James's University Hospital, Leeds LS9 7TF, UK.

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http://linkinghub.elsevier.com/retrieve/pii/S147149140700145
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http://dx.doi.org/10.1016/j.molmed.2007.07.005DOI Listing
September 2007

A proposed classification of the immunological diseases.

PLoS Med 2006 Aug;3(8):e297

Leeds Institute of Molecular Medicine, St. James's University Hospital, Leeds, United Kingdom.

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http://dx.plos.org/10.1371/journal.pmed.0030297
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http://dx.doi.org/10.1371/journal.pmed.0030297DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1564298PMC
August 2006

Hereditary auto-inflammatory disorders and biologics.

Springer Semin Immunopathol 2006 Jun 4;27(4):494-508. Epub 2006 May 4.

Academic Unit of Musculoskeletal Disease, Leeds Institute of Molecular Medicine, Epidemiology and Cancer Research, University of Leeds, Leeds, UK.

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http://dx.doi.org/10.1007/s00281-006-0015-6DOI Listing
June 2006

Improving pediatric asthma care through surveillance: the Illinois Emergency Department Asthma Collaborative.

Pediatrics 2006 Apr;117(4 Pt 2):S96-105

Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Rush University Medical Center, 1653 W Congress Pkwy, Jelke 297, Chicago, Illinois 60612, USA.

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http://dx.doi.org/10.1542/peds.2005-2000GDOI Listing
April 2006

Adequacy of medical chart review to characterize emergency care for asthma: findings from the Illinois Emergency Department Asthma Collaborative.

Acad Emerg Med 2006 Mar 22;13(3):345-8. Epub 2006 Feb 22.

Department of Emergency Medicine, John H. Stroger, Jr. Hospital of Cook County, Chicago IL 60612, USA.

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http://dx.doi.org/10.1197/j.aem.2005.09.006DOI Listing
March 2006

The tumour necrosis factor receptor-associated periodic syndrome: current concepts.

Expert Rev Mol Med 2005 Oct 10;7(22):1-18. Epub 2005 Oct 10.

Genetics and Genomics Branch, NIAMS, National Institutes of Health, Building 9, Room 1W111, 9 Memorial Drive, Bethesda, MD 20892-0908, USA.

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http://dx.doi.org/10.1017/S1462399405009749DOI Listing
October 2005

A common pathway in periodic fever syndromes.

Trends Immunol 2004 Sep;25(9):457-60

Department of Diabetes and Metabolic Medicine, Unit of Molecular Medicine, Barts and the London, Queen Mary's School of Medicine and Dentistry, University of London, London, UK.

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http://dx.doi.org/10.1016/j.it.2004.07.007DOI Listing
September 2004

Response to anakinra in a de novo case of neonatal-onset multisystem inflammatory disease.

Arthritis Rheum 2004 Aug;50(8):2708-9

Royal Free and University College, Medical School, London, UK.

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http://doi.wiley.com/10.1002/art.20357
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http://dx.doi.org/10.1002/art.20357DOI Listing
August 2004

The major histocompatibility complex origin.

Immunol Rev 2004 Apr;198:216-32

Phylogenomics Laboratory, Université d'Aix Marseille I, Marseille, France.

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http://dx.doi.org/10.1111/j.0105-2896.2004.00132.xDOI Listing
April 2004

NALP3 forms an IL-1beta-processing inflammasome with increased activity in Muckle-Wells autoinflammatory disorder.

Immunity 2004 Mar;20(3):319-25

Department of Biochemistry, University of Lausanne, Chemin des Boveresses 155, CH-1066 Epalinges, Switzerland.

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http://dx.doi.org/10.1016/s1074-7613(04)00046-9DOI Listing
March 2004

Spectrum of clinical features in Muckle-Wells syndrome and response to anakinra.

Arthritis Rheum 2004 Feb;50(2):607-12

Royal Free and University College Medical School, Royal Free Hospital, London, UK.

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http://doi.wiley.com/10.1002/art.20033
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http://dx.doi.org/10.1002/art.20033DOI Listing
February 2004

BMS-561392. Bristol-Myers Squibb.

Curr Opin Investig Drugs 2003 May;4(5):598-602

Department of Diabetes and Metabolic Medicine, Queen Mary, University of London, Mile End Road, London E1 1BB, UK.

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May 2003

Genetic clues to understanding periodic fevers, and possible therapies.

Trends Mol Med 2002 Dec;8(12):550-4

Dept of Diabetes and Metabolic Medicine, Unit of Molecular Medicine, Barts and the London, Queen Mary's School of Medicine and Dentistry, University of London, UK.

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December 2002

The autoinflammatory syndromes.

Curr Opin Allergy Clin Immunol 2002 Dec;2(6):511-6

aUnit of Molecular Medicine, Department of Diabetes and Metabolic Medicine, Barts and the London, Queen Mary School of Medicine and Dentistry, University of London, London, UK.

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http://dx.doi.org/10.1097/01.all.0000044536.45448.2dDOI Listing
December 2002

Vitamin D receptor (VDR) mRNA and VDR protein levels in relation to vitamin D status, insulin secretory capacity, and VDR genotype in Bangladeshi Asians.

Diabetes 2002 Jul;51(7):2294-300

Department of Diabetes and Metabolic Medicine, Barts and the London Queen Mary's School of Medicine and Dentistry, University of London, Royal London Hospital, Whitechapel, London E1 1BB, UK.

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http://dx.doi.org/10.2337/diabetes.51.7.2294DOI Listing
July 2002