Publications by authors named "Michael E Symonds"

100Publications

Adipose tissue growth and development: the modulating role of ambient temperature.

J Endocrinol 2020 Nov 1. Epub 2020 Nov 1.

H Budge, Academic Child Health, University of Nottingham, Nottingham, NG7 2UH, United Kingdom of Great Britain and Northern Ireland.

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http://dx.doi.org/10.1530/JOE-20-0075DOI Listing
November 2020

Impact of acute exercise on immediate and following early post-exercise FGF-21 concentration in adults: systematic review and meta-analysis.

Hormones (Athens) 2020 Nov 5. Epub 2020 Nov 5.

Health, Economy, Motricity and Education Research Group (HEME), Faculty of Sport Sciences, University of Extremadura, 10003, Caceres, Spain.

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http://dx.doi.org/10.1007/s42000-020-00245-3DOI Listing
November 2020

Association of serum and follicular fluid leptin and in vitro Fertilization/ ICSI outcome: A systematic review and meta-analysis.

J Gynecol Obstet Hum Reprod 2020 Sep 29:101924. Epub 2020 Sep 29.

Department of Genetics and Molecular Biology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran; Pediatric Inherited Diseases Research Center, Research Institute for Primordial Prevention of Non-Communicable Diseases Isfahan University of Medical Sciences, Isfahan, Iran. Electronic address:

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http://dx.doi.org/10.1016/j.jogoh.2020.101924DOI Listing
September 2020

Targeting Glutamine Synthesis Inhibits Stem Cell Adipogenesis in Vitro.

Cell Physiol Biochem 2020 Sep;54(5):917-927

School of Medicine, The University of Nottingham, UK,

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http://dx.doi.org/10.33594/000000278DOI Listing
September 2020

Cold-induced beigeing of stem cell-derived adipocytes is not fully reversible after return to normothermia.

J Cell Mol Med 2020 Oct 9;24(19):11434-11444. Epub 2020 Sep 9.

Wolfson STEM Centre, School of Medicine, The University of Nottingham, Nottingham, UK.

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http://dx.doi.org/10.1111/jcmm.15749DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7576274PMC
October 2020

The impact of high-intensity interval training on inflammatory markers in metabolic disorders: A meta-analysis.

Scand J Med Sci Sports 2020 Jun 25. Epub 2020 Jun 25.

The Early Life Research Unit, Division of Child Health, Obstetrics and Gynaecology, and Nottingham Digestive Disease Centre and Biomedical Research Centre, School of Medicine, University of Nottingham, Nottingham, UK.

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http://dx.doi.org/10.1111/sms.13754DOI Listing
June 2020

Effect of Bariatric Surgery on the Circulating Level of Adiponectin, Chemerin, Plasminogen Activator Inhibitor-1, Leptin, Resistin, and Visfatin: A Systematic Review and Meta-Analysis.

Horm Metab Res 2020 Apr 8;52(4):207-215. Epub 2020 Apr 8.

Department of Cellular and Molecular Nutrition, Tehran University of Medical Sciences, Tehran, Iran.

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http://dx.doi.org/10.1055/a-1129-6785DOI Listing
April 2020

Exercise Training in Obese Rats Does Not Induce Browning at Thermoneutrality and Induces a Muscle-Like Signature in Brown Adipose Tissue.

Front Endocrinol (Lausanne) 2020 20;11:97. Epub 2020 Mar 20.

The Early Life Research Unit, Division of Child Health, Obstetrics and Gynaecology, School of Medicine, University of Nottingham, Nottingham, United Kingdom.

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http://dx.doi.org/10.3389/fendo.2020.00097DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7099615PMC
March 2020

Food insecurity and mental health: a systematic review and meta-analysis.

Public Health Nutr 2020 07 16;23(10):1778-1790. Epub 2020 Mar 16.

Cancer Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

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http://dx.doi.org/10.1017/S136898001900435XDOI Listing
July 2020

Erratum to "Efficacy of l-carnitine supplementation for management of blood lipids: A systematic review and dose-response meta-analysis of randomized controlled trials" [Nutr Metabol Cardiovasc Dis 29 (11) (2019) 1151-1167].

Nutr Metab Cardiovasc Dis 2020 Mar 6;30(3):545. Epub 2020 Jan 6.

Students' Scientific Research Center (SSRC), Tehran University of Medical Sciences (TUMS), Tehran, Iran; Department of Cellular and Molecular Nutrition, School of Nutritional Sciences and Dietetics, Tehran University of Medical Sciences, Tehran, Iran. Electronic address:

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http://dx.doi.org/10.1016/j.numecd.2019.12.001DOI Listing
March 2020

Sleep duration and sarcopenia risk: a systematic review and dose-response meta-analysis.

Sleep Breath 2020 Dec 12;24(4):1267-1278. Epub 2019 Dec 12.

Cancer Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

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http://dx.doi.org/10.1007/s11325-019-01965-6DOI Listing
December 2020

Brown Adipose Tissue Response to Cold Stimulation Is Reduced in Girls With Autoimmune Hypothyroidism.

J Endocr Soc 2019 Dec 11;3(12):2411-2426. Epub 2019 Oct 11.

Early Life Research Unit, Division of Child Health, Obstetrics and Gynaecology, University of Nottingham, Nottingham, United Kingdom.

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http://dx.doi.org/10.1210/js.2019-00342DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6872489PMC
December 2019

Beneficial effects of l-carnitine supplementation for weight management in overweight and obese adults: An updated systematic review and dose-response meta-analysis of randomized controlled trials.

Pharmacol Res 2020 01 17;151:104554. Epub 2019 Nov 17.

Students' Scientific Research Center (SSRC), Tehran University of Medical Sciences (TUMS), Tehran, Iran; Department of Cellular and Molecular Nutrition, School of Nutritional Sciences and Dietetics, Tehran University of Medical Sciences, Tehran, Iran. Electronic address:

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http://dx.doi.org/10.1016/j.phrs.2019.104554DOI Listing
January 2020

Effects of strawberry supplementation on cardiovascular risk factors: a comprehensive systematic review and meta-analysis of randomized controlled trials.

Food Funct 2019 Nov 22;10(11):6987-6998. Epub 2019 Oct 22.

Students' Scientific Research Center (SSRC), Tehran University of Medical Sciences (TUMS), Tehran, Iran and Department of Cellular and Molecular Nutrition, School of Nutritional Sciences and Dietetics, Tehran University of Medical Sciences, Tehran, Iran.

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http://dx.doi.org/10.1039/c9fo01684hDOI Listing
November 2019

Efficacy of l-carnitine supplementation for management of blood lipids: A systematic review and dose-response meta-analysis of randomized controlled trials.

Nutr Metab Cardiovasc Dis 2019 11 24;29(11):1151-1167. Epub 2019 Jul 24.

Students' Scientific Research Center (SSRC), Tehran University of Medical Sciences (TUMS), Tehran, Iran; Department of Cellular and Molecular Nutrition, School of Nutritional Sciences and Dietetics, Tehran University of Medical Sciences, Tehran, Iran. Electronic address:

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http://dx.doi.org/10.1016/j.numecd.2019.07.012DOI Listing
November 2019

Editorial: Epigenetics in Mammalian Tissues.

Front Genet 2019 5;10:635. Epub 2019 Jul 5.

Early Life Research Unit, Division of Child Health, Obstetrics and Gynaecology, and Nottingham Digestive Disease Centre and Biomedical Research Centre, School of Medicine, University of Nottingham, Nottingham, United Kingdom.

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http://dx.doi.org/10.3389/fgene.2019.00635DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6624232PMC
July 2019

Policosanol supplementation significantly improves blood pressure among adults: A systematic review and meta-analysis of randomized controlled trials.

Complement Ther Med 2019 Aug 23;45:89-97. Epub 2019 May 23.

Cancer Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran; The Early Life Research Unit, Academic Division of Child Health, Obstetrics and Gynaecology, and Nottingham Digestive Disease Centre and Biomedical Research Centre, The School of Medicine, University of Nottingham, Nottingham, NG7 2UH, UK; The Early Life Research Unit, Division of Child Health, Obstetrics and Gynaecology, University ofNottingham, Nottingham, UK. Electronic address:

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http://dx.doi.org/10.1016/j.ctim.2019.05.023DOI Listing
August 2019

Live Simultaneous Monitoring of Mineral Deposition and Lipid Accumulation in Differentiating Stem Cells.

Biomimetics (Basel) 2019 Jul 10;4(3). Epub 2019 Jul 10.

Wolfson STEM Centre, School of Medicine, The University of Nottingham, Nottingham NG7 2RD, UK.

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http://dx.doi.org/10.3390/biomimetics4030048DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6784299PMC
July 2019

Caffeine exposure induces browning features in adipose tissue in vitro and in vivo.

Sci Rep 2019 06 24;9(1):9104. Epub 2019 Jun 24.

Wolfson Centre for Stem Cells, Tissue Engineering and Modelling (STEM), Division of Cancer & Stem Cells, University of Nottingham, Nottingham, NG7 2UH, United Kingdom.

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http://dx.doi.org/10.1038/s41598-019-45540-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6591281PMC
June 2019

Interscapular and Perivascular Brown Adipose Tissue Respond Differently to a Short-Term High-Fat Diet.

Nutrients 2019 May 13;11(5). Epub 2019 May 13.

The Early Life Research Unit, Division of Child Health, Obstetrics and Gynaecology, School of Medicine, University of Nottingham NG7 2UH, UK.

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http://dx.doi.org/10.3390/nu11051065DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6566556PMC
May 2019

Sexual Dimorphism of Brown Adipose Tissue Function.

J Pediatr 2019 07 9;210:166-172.e1. Epub 2019 Apr 9.

Division of Child Health, Obstetrics and Gynecology, University of Nottingham, Nottingham, UK.

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http://dx.doi.org/10.1016/j.jpeds.2019.03.003DOI Listing
July 2019

Housing Temperature Modulates the Impact of Diet-Induced Rise in Fat Mass on Adipose Tissue Before and During Pregnancy in Rats.

Front Physiol 2019 6;10:209. Epub 2019 Mar 6.

Early Life Research Unit, Division of Child Health, Obstetrics, and Gynaecology, University of Nottingham, Nottingham, United Kingdom.

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http://dx.doi.org/10.3389/fphys.2019.00209DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6414463PMC
March 2019

Brown adipose tissue and glucose homeostasis - the link between climate change and the global rise in obesity and diabetes.

Adipocyte 2019 12 3;8(1):46-50. Epub 2018 Dec 3.

a Early Life Research Unit, Division of Child Health , Obstetrics & Gynaecology, School of Medicine, University of Nottingham , Nottingham , UK.

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http://dx.doi.org/10.1080/21623945.2018.1551689DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6768202PMC
December 2019

The use of infrared thermography in the measurement and characterization of brown adipose tissue activation.

Temperature (Austin) 2018 29;5(2):147-161. Epub 2018 Jan 29.

Early Life Research Unit, Division of Child Health, Obstetrics & Gynaecology, School of Medicine, University of Nottingham, Nottingham, United Kingdom.

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https://www.tandfonline.com/doi/full/10.1080/23328940.2017.1
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http://dx.doi.org/10.1080/23328940.2017.1397085DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6209420PMC
January 2018

Comprehensive literature search for animal studies may have saved STRIDER trial.

BMJ 2018 Sep 25;362:k4007. Epub 2018 Sep 25.

Early Life Research Unit, Division of Child Health, Obstetrics and Gynaecology, Nottingham Digestive Disease Centre and Biomedical Research Centre, School of Medicine, University of Nottingham, Nottingham NG7 2UH, UK.

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http://dx.doi.org/10.1136/bmj.k4007DOI Listing
September 2018

Recent advances in our understanding of brown and beige adipose tissue: the good fat that keeps you healthy.

F1000Res 2018 24;7. Epub 2018 Jul 24.

Early Life Research Unit, Division of Child Health, Obstetrics & Gynaecology, School of Medicine, University of Nottingham, Nottingham, UK.

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http://dx.doi.org/10.12688/f1000research.14585.1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058473PMC
July 2018

Infrared Thermography.

Handb Exp Pharmacol 2019 ;251:259-282

School of Medicine, Faculty of Medicine and Health Sciences, University of Nottingham, Nottingham, UK.

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http://dx.doi.org/10.1007/164_2018_137DOI Listing
July 2019

High Fructose Intake During Pregnancy in Rats Influences the Maternal Microbiome and Gut Development in the Offspring.

Front Genet 2018 19;9:203. Epub 2018 Jun 19.

Division of Human Nutrition, Department of Agricultural, Food and Nutritional Science, University of Alberta, Edmonton, AB, Canada.

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http://dx.doi.org/10.3389/fgene.2018.00203DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6018152PMC
June 2018

Brown adipose tissue development and function and its impact on reproduction.

J Endocrinol 2018 07 22;238(1):R53-R62. Epub 2018 May 22.

Early Life Research UnitDivision of Child Health, Obstetrics & Gynaecology, School of Medicine, University of Nottingham, Nottingham, UK.

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http://dx.doi.org/10.1530/JOE-18-0084DOI Listing
July 2018

Exercise-induced 'browning' of adipose tissues.

Metabolism 2018 04 16;81:63-70. Epub 2017 Nov 16.

The Early Life Research Unit, Division of Child Health, Obstetrics and Gynaecology, University of Nottingham, Nottingham NG7 2UH, UK; Nottingham Digestive Disease Centre and Biomedical Research Centre School of Medicine, University Hospital, University of Nottingham, Nottingham, UK, NG7 2UH. Electronic address:

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http://dx.doi.org/10.1016/j.metabol.2017.11.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5893183PMC
April 2018

Thermal Imaging Is a Noninvasive Alternative to PET/CT for Measurement of Brown Adipose Tissue Activity in Humans.

J Nucl Med 2018 03 14;59(3):516-522. Epub 2017 Sep 14.

Early Life Research Unit, Division of Child Health, Obstetrics, and Gynaecology, School of Medicine, University of Nottingham, Nottingham, United Kingdom

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http://dx.doi.org/10.2967/jnumed.117.190546DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5868502PMC
March 2018

Tissue cell stress response to obesity and its interaction with late gestation diet.

Reprod Fertil Dev 2018 Mar;30(3):430-441

Early Life Research Unit, Academic Division of Child Health, Obstetrics and Gynaecology, School of Medicine, Queen's Medical Centre, University of Nottingham, Nottingham NG7 2UH, UK.

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http://dx.doi.org/10.1071/RD16494DOI Listing
March 2018

Beyond obesity - thermogenic adipocytes and cardiometabolic health.

Horm Mol Biol Clin Investig 2017 May 26;31(2). Epub 2017 May 26.

.

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http://dx.doi.org/10.1515/hmbci-2017-0007DOI Listing
May 2017

Ontogeny and Thermogenic Role for Sternal Fat in Female Sheep.

Endocrinology 2017 07;158(7):2212-2225

Early Life Research Unit, Division of Child Health, Obstetrics & Gynaecology, School of Medicine, University of Nottingham, Nottingham NG7 2UH, United Kingdom.

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http://dx.doi.org/10.1210/en.2017-00081DOI Listing
July 2017

Glucocorticoids modulate human brown adipose tissue thermogenesis in vivo.

Metabolism 2017 May 19;70:125-132. Epub 2017 Jan 19.

Institute of Metabolism and Systems Research, University of Birmingham, Birmingham, B15 2TT, UK; Centre for Endocrinology, Diabetes and Metabolism, Birmingham Health Partners, Birmingham, B15 2TT, UK. Electronic address:

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http://dx.doi.org/10.1016/j.metabol.2017.01.024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5395593PMC
May 2017

Lifetime Exposure to a Constant Environment Amplifies the Impact of a Fructose-Rich Diet on Glucose Homeostasis during Pregnancy.

Nutrients 2017 Mar 25;9(4). Epub 2017 Mar 25.

Division of Human Nutrition, Department of Agricultural, Food and Nutritional Sciences, University of Alberta, Edmonton, AB T6G 2E1, Canada.

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http://dx.doi.org/10.3390/nu9040327DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5409666PMC
March 2017

The Placenta, Maternal Diet and Adipose Tissue Development in the Newborn.

Ann Nutr Metab 2017 17;70(3):232-235. Epub 2017 Mar 17.

Early Life Research Unit, Academic Division of Child Health, Obstetrics and Gynaecology, The University of Nottingham, Nottingham, UK.

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http://dx.doi.org/10.1159/000464301DOI Listing
February 2018

'Browning' the cardiac and peri-vascular adipose tissues to modulate cardiovascular risk.

Int J Cardiol 2017 Feb 9;228:265-274. Epub 2016 Nov 9.

The Early Life Research Unit, Division of Child Health, Obstetrics and Gynaecology, School of Medicine, University Hospital, University of Nottingham, Nottingham, UK, NG7 2UH. Electronic address:

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http://dx.doi.org/10.1016/j.ijcard.2016.11.074DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5236060PMC
February 2017

Adipocyte Browning and Higher Mitochondrial Function in Periadrenal But Not SC Fat in Pheochromocytoma.

J Clin Endocrinol Metab 2016 11 30;101(11):4440-4448. Epub 2016 Aug 30.

Department of Human Genetics (L.V., J.Y.L., K.R.), David Geffen School of Medicine at UCLA, Los Angeles, California; Academic Division of Child Health, Obstetrics and Gynaecology (G.R.D., M.E.S.), School of Medicine, Queen's Medical Centre, The University of Nottingham, Nottingham, United Kingdom; Section of Endocrine Surgery (M.W.Y., M.J.L., A.H.), David Geffen School of Medicine at UCLA, Los Angeles, California; Endocrinology and Diabetes Division (H.S.S.), VA Greater Los Angeles Healthcare System, Department of Medicine, David Geffen School of Medicine at UCLA, Los Angeles, California; Molecular Biology Institute (K.R.), University of California, Los Angeles, Los Angeles, California.

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https://academic.oup.com/jcem/article-lookup/doi/10.1210/jc.
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http://dx.doi.org/10.1210/jc.2016-2670DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5095230PMC
November 2016

Gene pathway development in human epicardial adipose tissue during early life.

JCI Insight 2016 08 18;1(13):e87460. Epub 2016 Aug 18.

Division of Child Health, Obstetrics and Gynaecology, School of Medicine, Queen's Medical Centre, University Hospital, The University of Nottingham, Nottingham, United Kingdom.

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http://dx.doi.org/10.1172/jci.insight.87460DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5033935PMC
August 2016

Brown adipose tissue activation as measured by infrared thermography by mild anticipatory psychological stress in lean healthy females.

Exp Physiol 2016 Apr 18;101(4):549-57. Epub 2016 Feb 18.

The Early Life Research Unit, Division of Child Health, Obstetrics and Gynaecology, School of Medicine, University Hospital, University of Nottingham, Nottingham, NG7 2UH, UK.

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http://doi.wiley.com/10.1113/EP085642
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http://dx.doi.org/10.1113/EP085642DOI Listing
April 2016

Nutrient availability, the microbiome, and intestinal transport during pregnancy.

Appl Physiol Nutr Metab 2015 Nov 4;40(11):1100-6. Epub 2015 Aug 4.

a Department of Agricultural, Food and Nutritional Science, Human Nutrition, Alberta Diabetes Institute, University of Alberta, Edmonton, AB T6G 2E1, Canada.

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http://dx.doi.org/10.1139/apnm-2015-0117DOI Listing
November 2015

High fructose consumption in pregnancy alters the perinatal environment without increasing metabolic disease in the offspring.

Reprod Fertil Dev 2016 Oct;28(12):2007-2015

Division of Human Nutrition, Department of Agricultural, Food and Nutritional Sciences, University of Alberta, Edmonton, Alberta T6G 2E1, Canada.

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http://www.publish.csiro.au/?paper=RD15119
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http://dx.doi.org/10.1071/RD15119DOI Listing
October 2016

The Ontogeny of Brown Adipose Tissue.

Annu Rev Nutr 2015 6;35:295-320. Epub 2015 May 6.

Division of Child Health, Obstetrics and Gynaecology, School of Medicine, University of Nottingham, Nottingham NG7 2UH, United Kingdom; email: , ,

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http://dx.doi.org/10.1146/annurev-nutr-071813-105330DOI Listing
April 2016

Effect of pre- and postnatal growth and post-weaning activity on glucose metabolism in the offspring.

J Endocrinol 2015 Feb 21;224(2):171-82. Epub 2014 Nov 21.

Early Life Research UnitAcademic Division of Child Health, Obstetrics and Gynaecology, School of Medicine, Queen's Medical Centre, The University of Nottingham, Nottingham NG7 2UH, UKINRA and University of NantesUMR-1280 Physiologie des Adaptations Nutritionnelles, CHU Hôtel Dieu, 44093 Nantes cedex 1, FranceSchool of Veterinary Medicine and ScienceThe University of Nottingham, Sutton Bonington Campus, Nottingham LE12 5RD, UKInstitute of Health SciencesCentre for Life-Course Epidemiology, and Biocentre Oulu, University of Oulu, Aapistie 5B, 90014 Oulu, FinlandOnirisLaboratoire d'Etude des Résidus et Contaminants dans les Aliments, LUNAM Université, USC INRA 1329, Nantes, FranceDepartment of Animal ScienceUniversity of Missouri, Columbia, Missouri 65211, USA Early Life Research UnitAcademic Division of Child Health, Obstetrics and Gynaecology, School of Medicine, Queen's Medical Centre, The University of Nottingham, Nottingham NG7 2UH, UKINRA and University of NantesUMR-1280 Physiologie des Adaptations Nutritionnelles, CHU Hôtel Dieu, 44093 Nantes cedex 1, FranceSchool of Veterinary Medicine and ScienceThe University of Nottingham, Sutton Bonington Campus, Nottingham LE12 5RD, UKInstitute of Health SciencesCentre for Life-Course Epidemiology, and Biocentre Oulu, University of Oulu, Aapistie 5B, 90014 Oulu, FinlandOnirisLaboratoire d'Etude des Résidus et Contaminants dans les Aliments, LUNAM Université, USC INRA 1329, Nantes, FranceDepartment of Animal ScienceUniversity of Missouri, Columbia, Missouri 65211, USA.

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http://dx.doi.org/10.1530/JOE-14-0600DOI Listing
February 2015

The influence of sex steroids on adipose tissue growth and function.

Horm Mol Biol Clin Investig 2014 Jul;19(1):13-24

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http://dx.doi.org/10.1515/hmbci-2014-0015DOI Listing
July 2014

Getting rhythm: how do babies do it?

Arch Dis Child Fetal Neonatal Ed 2015 Jan 22;100(1):F50-4. Epub 2014 Sep 22.

College of Medicine, Biological Sciences and Psychology, University of Leicester, Leicester, UK.

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http://dx.doi.org/10.1136/archdischild-2014-306104DOI Listing
January 2015

UCP1 is present in porcine adipose tissue and is responsive to postnatal leptin.

J Endocrinol 2014 Oct 13;223(1):M31-8. Epub 2014 Aug 13.

UP 2012.10.101 EGEALInstitut Polytechnique LaSalle, Beauvais, FranceSchool of Veterinary Medicine and ScienceUniversity of Nottingham, Sutton Bonington Campus, LE12 5RD Nottingham, UKINRA UMR 703Ecole Nationale Vétérinaire, Nantes, FranceINRAUMR1198 BDR Biologie du Développement et Reproduction, Jouy-en-Josas, FranceUnité de Recherche 04UR08/03Faculté de Médecine, Tunis, TunisiaThe Hebrew University of JerusalemPO Box 12, Rehovot 76100, IsraelUnité NOPAINRA, Centre de recherche Jouy en Josas, Jouy-en-Josas, FranceEarly Life Research UnitAcademic Child Health, School of Medicine, University Hospital, The University of Nottingham, Nottingham NG7 2UH, UK

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https://joe.bioscientifica.com/view/journals/joe/223/1/M31.x
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http://dx.doi.org/10.1530/JOE-14-0155DOI Listing
October 2014

Suboptimal maternal nutrition during early-to-mid gestation in the sheep enhances pericardial adiposity in the near-term fetus.

Reprod Fertil Dev 2015 Nov;27(8):1205-12

Division of Child Health, Obstetrics and Gynaecology, School of Medicine, University of Nottingham, Nottingham NG7 2UH, UK.

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http://dx.doi.org/10.1071/RD14007DOI Listing
November 2015

Ethnicity and its effects on brown adipose tissue.

Lancet Diabetes Endocrinol 2014 Mar 12;2(3):185-6. Epub 2013 Nov 12.

Division of Child Health, Obstetrics and Gynaecology, School of Medicine, The University of Nottingham, Queen's Medical Centre, Nottingham NG7 2UH, UK. Electronic address:

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http://dx.doi.org/10.1016/S2213-8587(13)70177-3DOI Listing
March 2014

Sexual dimorphism in white and brown adipose tissue with obesity and inflammation.

Horm Behav 2014 Jun 28;66(1):95-103. Epub 2014 Feb 28.

Early Life Research Unit, Division of Child Health, Obstetrics and Gynaecology, School of Medicine, The University of Nottingham, Queen's Medical Centre, Nottingham, NG7 2UH, UK. Electronic address:

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http://dx.doi.org/10.1016/j.yhbeh.2014.02.007DOI Listing
June 2014

Public-private collaboration in clinical research during pregnancy, lactation, and childhood: joint position statement of the Early Nutrition Academy and the European Society for Pediatric Gastroenterology, Hepatology, and Nutrition.

J Pediatr Gastroenterol Nutr 2014 Apr;58(4):525-30

*Dr von Hauner Children's Hospital, Ludwig-Maximilians-University, Munich, Germany †Emma Children's Hospital/Academic Medical Centre, Department of Pediatric Gastroenterology & Nutrition, Amsterdam, The Netherlands ‡MRC Lifecourse Epidemiology Unit and NIHR Southampton Biomedical Research Centre, University of Southampton and University Hospital Southampton NHS Foundation Trust, Southampton, UK §Gynecology and Obstetrics, Hvidovre Hospital, Copenhagen, Denmark ||Children's Hospital Zagreb University Medical School, Zagreb, Croatia ¶Children's Hospital Medical Center, University Hospitals, Bonn, Germany #European Foundation for the Care of Newborn Infants, Munich, Germany **UCD Obstetrics & Gynaecology, School of Medicine and Medical Science, University College Dublin, National Maternity Hospital, Dublin, Ireland ††Department of Obstetrics, Leiden University Medical Centre, Leiden, The Netherlands ‡‡Telethon Institute for Child Health Research, Centre for Child Health Research, University of Western Australia, West Perth, Australia §§UCL Institute of Child Health, London, UK ||||Children's Memorial Health Institute ¶¶Department of Paediatrics, Medical University of Warsaw, Poland ##Academic Division of Child Health, School of Clinical Sciences, University of Nottingham, Nottingham, UK ***European Medicine Agency, Emma Children's Hospital, Academic Medical Centre, Amsterdam, The Netherlands †††UCL Institute of Child Health, Great Ormond Street Hospital, London, UK ‡‡‡Department of Paediatrics, Universita degli Studi di Napoli Frederico II, Naples, Italy §§§Department of Paediatrics, UZ Brussel, Vrije Universiteit Brussel, Brussels, Belgium.

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April 2014

Brown adipose tissue growth and development.

Scientifica (Cairo) 2013 31;2013:305763. Epub 2013 Mar 31.

Early Life Nutrition Research Unit, Academic Division of Child Health, School of Clinical Sciences, University Hospital, The University of Nottingham, Nottingham NG7 2UH, UK.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3820149PMC
November 2013

Body mass index as a determinant of brown adipose tissue function in healthy children.

J Pediatr 2014 Feb 14;164(2):318-22.e1. Epub 2013 Nov 14.

Early Life Research Unit, Academic Child Health, School of Medicine, University Hospital, University of Nottingham, Nottingham, United Kingdom.

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http://dx.doi.org/10.1016/j.jpeds.2013.10.005DOI Listing
February 2014

Epigenetics and obesity: a relationship waiting to be explained.

Hum Hered 2013 27;75(2-4):90-7. Epub 2013 Sep 27.

Early Life Nutrition Research Unit, Academic Division of Child Health, School of Medicine, University Hospital, The University of Nottingham, Nottingham, UK.

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http://dx.doi.org/10.1159/000352009DOI Listing
April 2014

Suboptimal maternal nutrition affects offspring health in adult life.

Early Hum Dev 2013 Nov 27;89(11):909-13. Epub 2013 Sep 27.

The Early Life Research Unit, Academic Child Health, School of Medicine, The University of Nottingham, Nottingham, NG7 2UH, UK. Electronic address:

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November 2013

Sex differences in metabolic and adipose tissue responses to juvenile-onset obesity in sheep.

Endocrinology 2013 Oct 24;154(10):3622-31. Epub 2013 Jul 24.

Academic Division of Child Health School of Clinical Sciences, E Floor, East Block, Queen's Medical Centre, University Hospital, The University of Nottingham, Nottingham NG7 2UH, United Kingdom.

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October 2013

Adult epicardial fat exhibits beige features.

J Clin Endocrinol Metab 2013 Sep 3;98(9):E1448-55. Epub 2013 Jul 3.

VA Greater Los Angeles Healthcare System, Endocrinology and Diabetes Division 111D, 11310 Wilshire Boulevard, Los Angeles, California 90073, USA.

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September 2013

Brown adipose tissue genes in pericardial adipose tissue of newborn sheep are downregulated by maternal nutrient restriction in late gestation.

Pediatr Res 2013 Sep 20;74(3):246-51. Epub 2013 Jun 20.

Academic Child Health, School of Medicine, University of Nottingham, Nottingham, UK.

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http://dx.doi.org/10.1038/pr.2013.107DOI Listing
September 2013

Anatomical locations of human brown adipose tissue: functional relevance and implications in obesity and type 2 diabetes.

Diabetes 2013 Jun;62(6):1783-90

Endocrinology and Diabetes Division, VA Greater Los Angeles Healthcare System, Los Angeles, California, USA.

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http://dx.doi.org/10.2337/db12-1430DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3661606PMC
June 2013

Brown adipose tissue: a new human organ?

Expert Rev Endocrinol Metab 2013 Mar;8(2):123-125

b Academic Child Health, School of Clinical Sciences, University Hospital, University of Nottingham, Nottingham, NG7 2UH, UK.

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http://dx.doi.org/10.1586/eem.13.6DOI Listing
March 2013

Early life nutritional programming of obesity: mother-child cohort studies.

Ann Nutr Metab 2013 5;62(2):137-45. Epub 2013 Feb 5.

Early Life Nutrition Research Unit, Academic Division of Child Health School of Medicine, Queen's Medical Centre, University Hospital, University of Nottingham, Nottingham, UK.

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September 2013

Excess nutrient supply in early life and its later metabolic consequences.

Clin Exp Pharmacol Physiol 2013 Nov;40(11):817-23

The Early Life Nutrition Research Unit, Academic Division of Child Health, School of Clinical Sciences, University Hospital, The University of Nottingham, Nottingham, UK.

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November 2013

Prevalence and pattern of brown adipose tissue distribution of 18F-FDG in patients undergoing PET-CT in a subtropical climatic zone.

Nucl Med Commun 2013 Feb;34(2):168-74

Radiological and Imaging Sciences, Medical Physics, Medical School Queen’s Medical Centre, University of Nottingham, Nottingham, NG7 2UH, UK.

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February 2013

The influence of sex on early stage markers of kidney dysfunction in response to juvenile obesity.

Hypertension 2012 Oct 4;60(4):991-7. Epub 2012 Sep 4.

Early Life Nutrition Research Unit, Academic Division of Child Health, School of Medicine, E Floor, East Block, Queen's Medical Centre, University Hospital, Nottingham, United Kingdom.

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http://dx.doi.org/10.1161/HYPERTENSIONAHA.112.195412DOI Listing
October 2012

Adipose tissue development during early life: novel insights into energy balance from small and large mammals.

Proc Nutr Soc 2012 Aug 18;71(3):363-70. Epub 2012 Jun 18.

The Early Life Nutrition Research Unit, Academic Child Health, School of Clinical Sciences, University Hospital, Nottingham NG7 2UH, UK.

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August 2012

Thermal imaging to assess age-related changes of skin temperature within the supraclavicular region co-locating with brown adipose tissue in healthy children.

J Pediatr 2012 Nov 5;161(5):892-8. Epub 2012 Jun 5.

The Early Life Nutrition Research Unit, Academic Division of Child Health, School of Clinical Sciences, University Hospital, Nottingham, United Kingdom.

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November 2012

The obesity epidemic: from the environment to epigenetics - not simply a response to dietary manipulation in a thermoneutral environment.

Front Genet 2011 31;2:24. Epub 2011 May 31.

Early Life Nutrition Research Unit, Academic Division of Child Health, Nottingham Respiratory Medicine Biomedical Research Unit, School of Clinical Sciences, University Hospital Nottingham, UK.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3268579PMC
October 2012

Programming research: where are we and where do we go from here?

Am J Clin Nutr 2011 Dec 16;94(6 Suppl):2036S-2043S. Epub 2011 Nov 16.

Division of Metabolic and Nutritional Medicine, Department of Pediatrics, Dr von Hauner Children's Hospital, University of Munich Medical Center, Munich, Germany.

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December 2011

The early programming of metabolic health: is epigenetic setting the missing link?

Am J Clin Nutr 2011 Dec 4;94(6 Suppl):1953S-1958S. Epub 2011 May 4.

Early Life Nutrition Research Unit, Academic Division of Child Health, and Nottingham Respiratory Medicine Biomedical Research Unit, School of Clinical Sciences, University Hospital Nottingham, Nottingham, United Kingdom.

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December 2011

Homocysteine and folate plasma concentrations in mother and baby at delivery after pre-eclamptic or normotensive pregnancy: Influence of parity.

Pregnancy Hypertens 2011 Apr 12;1(2):150-5. Epub 2011 Feb 12.

Department of Obstetrics and Gynaecology, School of Clinical Sciences, University of Nottingham, UK.

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April 2011

Adipose tissue development--impact of the early life environment.

Prog Biophys Mol Biol 2011 Jul 14;106(1):300-6. Epub 2010 Dec 14.

Early Life Nutrition Research Unit, Academic Child Health, School of Clinical Sciences, University Hospital, Nottingham NG72UH, United Kingdom.

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July 2011

Nutritional programming of the metabolic syndrome.

Nat Rev Endocrinol 2009 Nov 29;5(11):604-10. Epub 2009 Sep 29.

Early Life Nutrition Research Unit, Academic Child Health, Division of Human Development, School of Clinical Sciences, University Hospital, Nottingham, UK.

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http://dx.doi.org/10.1038/nrendo.2009.195DOI Listing
November 2009

Maternal nutrient restriction during early fetal kidney development attenuates the renal innate inflammatory response in obese young adult offspring.

Am J Physiol Renal Physiol 2009 Nov 16;297(5):F1199-207. Epub 2009 Sep 16.

Early Life Nutrition Research Group, Academic Child Health, University of Nottingham, Nottingham, United Kingdom.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2781328PMC
November 2009

Early programming of adipose tissue function: a large-animal perspective.

Proc Nutr Soc 2009 Nov 1;68(4):393-400. Epub 2009 Sep 1.

Early Life Nutrition Research Unit, Academic Child Health, Division of Human Development and Nottingham Respiratory Medicine Biomedical Research Unit, School of Clinical Sciences, Queen's Medical Centre, University Hospitals, Nottingham NG7 2UH, UK.

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November 2009

The impact of diet during early life and its contribution to later disease: critical checkpoints in development and their long-term consequences for metabolic health.

Proc Nutr Soc 2009 Nov 1;68(4):416-21. Epub 2009 Sep 1.

Early Life Nutrition Research Unit, Academic Child Health, Division of Human Development, and Nottingham Respiratory Medicine Biomedical Research Unit, School of Clinical Sciences, Queen's Medical Centre, University Hospitals, Nottingham NG7 2UH, UK.

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http://dx.doi.org/10.1017/S0029665109990152DOI Listing
November 2009

Brown adipose tissue and seasonal variation in humans.

Diabetes 2009 Nov 20;58(11):2583-7. Epub 2009 Aug 20.

Departments of Radiology and Nuclear Medicine, Queens Medical Centre, University Hospitals, Nottingham, U.K.

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http://dx.doi.org/10.2337/db09-0833DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2768171PMC
November 2009

Tissue specific adaptations to nutrient supply: more than just epigenetics?

Adv Exp Med Biol 2009 ;646:113-8

Centre for Reproduction and Early Life, Institute of Clinical Research, University Hospital, Nottingham, UK.

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http://dx.doi.org/10.1007/978-1-4020-9173-5_12DOI Listing
September 2009

Adipose tissue inflammation: developmental ontogeny and consequences of gestational nutrient restriction in offspring.

Endocrinology 2009 Aug 7;150(8):3913-20. Epub 2009 May 7.

Centre for Reproduction and Early Life, Institute of Clinical Research, University of Nottingham NG7 2UH, United Kingdom

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http://dx.doi.org/10.1210/en.2008-1784DOI Listing
August 2009

Impact of early onset obesity and hypertension on the unfolded protein response in renal tissues of juvenile sheep.

Hypertension 2009 Jun 4;53(6):925-31. Epub 2009 May 4.

Centre for Reproduction and Early Life, Institute of Clinical Research, University of Nottingham, Nottingham, United Kingdom.

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June 2009

Early determinants of cardiovascular disease: the role of early diet in later blood pressure control.

Am J Clin Nutr 2009 May 18;89(5):1518S-1522S. Epub 2009 Mar 18.

Centre for Reproduction and Early Life, the Institute of Clinical Research, the University of Nottingham, Nottingham, United Kingdom.

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http://dx.doi.org/10.3945/ajcn.2009.27113FDOI Listing
May 2009

Early developmental influences on hepatic organogenesis.

Organogenesis 2008 Jul;4(3):170-5

Centre for Reproduction and Early Life; Institute of Clinical Research; University of Nottingham UK.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2634976PMC
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July 2008

Nutritional models of the developmental programming of adult health and disease.

Proc Nutr Soc 2009 May 11;68(2):173-8. Epub 2009 Feb 11.

Centre for Reproduction and Early Life, Institute of Clinical Research, University Hospital, Nottingham, UK.

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http://dx.doi.org/10.1017/S0029665109001049DOI Listing
May 2009

Mathematical modeling of glucose homeostasis and its relationship with energy balance and body fat.

Obesity (Silver Spring) 2009 Apr 15;17(4):632-9. Epub 2009 Jan 15.

School of Biosciences, University of Nottingham, Sutton Bonington Campus, Loughborough, UK.

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http://dx.doi.org/10.1038/oby.2008.604DOI Listing
April 2009

Maternal nutrient restriction during pregnancy differentially alters the unfolded protein response in adipose and renal tissue of obese juvenile offspring.

FASEB J 2009 May 22;23(5):1314-24. Epub 2008 Dec 22.

Centre for Reproduction and Early Life, Institute of Clinical Research, University of Nottingham, Nottingham, UK.

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May 2009

Conference on "Multidisciplinary approaches to nutritional problems". Symposium on "Diabetes and health". Nutrition and its contribution to obesity and diabetes: a life-course approach to disease prevention?

Proc Nutr Soc 2009 Feb 10;68(1):71-7. Epub 2008 Dec 10.

Centre for Reproduction and Early Life, Institute of Clinical Research, University of Nottingham, NG72UH, UK.

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February 2009

Reduced selenium concentrations and glutathione peroxidase activity in preeclamptic pregnancies.

Hypertension 2008 Nov 13;52(5):881-8. Epub 2008 Oct 13.

Centre of Reproduction and Early Life, School of Human Development, University of Nottingham, United Kingdom.

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http://dx.doi.org/10.1161/HYPERTENSIONAHA.108.116103DOI Listing
November 2008

Maternal nutrient restriction is not equivalent to maternal biological stress.

Curr Drug Targets 2007 Aug;8(8):888-93

Centre for Reproduction and Early Life, Institute of Clinical Research, University of Nottingham, UK.

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August 2007

Ontogeny and nutritional programming of the hepatic growth hormone-insulin-like growth factor-prolactin axis in the sheep.

Endocrinology 2007 Oct 19;148(10):4754-60. Epub 2007 Jul 19.

Center for Reproduction and Early Life, Institute of Clinical Research, The University of Nottingham, Nottingham, UK.

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October 2007