Michael Duchêne

Michael Duchêne

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Michael Duchêne

Michael Duchêne

Publications by authors named "Michael Duchêne"

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35Publications

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Genetic Variation of Bordetella pertussis in Austria.

PLoS One 2015 16;10(7):e0132623. Epub 2015 Jul 16.

Institute of Specific Prophylaxis and Tropical Medicine, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, Vienna, Austria.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0132623PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4504479PMC
April 2016

Molecular and biochemical characterization of Entamoeba histolytica fructokinase.

Parasitol Res 2015 May 21;114(5):1939-47. Epub 2015 Feb 21.

Institute of Specific Prophylaxis and Tropical Medicine, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, Kinderspitalgasse 15, 1090, Vienna, Austria.

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http://dx.doi.org/10.1007/s00436-015-4383-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4412284PMC
May 2015

Trichomonas vaginalis flavin reductase 1 and its role in metronidazole resistance.

Mol Microbiol 2014 Jan 20;91(1):198-208. Epub 2013 Nov 20.

Institute of Specific Prophylaxis and Tropical Medicine, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.1111/mmi.12455DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4437529PMC
January 2014

Unexpected properties of NADP-dependent secondary alcohol dehydrogenase (ADH-1) in Trichomonas vaginalis and other microaerophilic parasites.

Exp Parasitol 2013 Jul 8;134(3):374-80. Epub 2013 Apr 8.

Institute of Specific Prophylaxis and Tropical Medicine, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.1016/j.exppara.2013.03.034DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3682184PMC
July 2013

Entamoeba histolytica: identification of thioredoxin-targeted proteins and analysis of serine acetyltransferase-1 as a prototype example.

Biochem J 2013 Apr;451(2):277-88

Institute of Specific Prophylaxis and Tropical Medicine, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, A-1090 Vienna, Austria.

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http://dx.doi.org/10.1042/BJ20121798DOI Listing
April 2013

Nitroimidazole drugs vary in their mode of action in the human parasite Giardia lamblia.

Int J Parasitol Drugs Drug Resist 2012 Dec 12;2:166-70. Epub 2012 May 12.

Institute of Specific Prophylaxis and Tropical Medicine at the Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.1016/j.ijpddr.2012.04.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3862438PMC
December 2012

Thioredoxin from the Indianmeal moth Plodia interpunctella: cloning and test of the allergenic potential in mice.

PLoS One 2012 26;7(7):e42026. Epub 2012 Jul 26.

Institute of Specific Prophylaxis and Tropical Medicine, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, Vienna, Austria.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0042026PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3406034PMC
November 2012

Down-regulation of flavin reductase and alcohol dehydrogenase-1 (ADH1) in metronidazole-resistant isolates of Trichomonas vaginalis.

Mol Biochem Parasitol 2012 Jun 17;183(2):177-83. Epub 2012 Mar 17.

Institute of Specific Prophylaxis and Tropical Medicine at the Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, 1090 Vienna, Austria.

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http://dx.doi.org/10.1016/j.molbiopara.2012.03.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3341570PMC
June 2012

Pyruvate:ferredoxin oxidoreductase and thioredoxin reductase are involved in 5-nitroimidazole activation while flavin metabolism is linked to 5-nitroimidazole resistance in Giardia lamblia.

J Antimicrob Chemother 2011 Aug 22;66(8):1756-65. Epub 2011 May 22.

Institute of Specific Prophylaxis and Tropical Medicine, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, Vienna, Austria.

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https://academic.oup.com/jac/article-lookup/doi/10.1093/jac/
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http://dx.doi.org/10.1093/jac/dkr192DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3133484PMC
August 2011

Anti-leishmanial activity of plant-derived acridones, flavaglines, and sulfur-containing amides.

Vector Borne Zoonotic Dis 2011 Jul 21;11(7):793-8. Epub 2011 Mar 21.

Institute of Specific Prophylaxis and Tropical Medicine, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.1089/vbz.2010.0087DOI Listing
July 2011

In vitro activity of N-chlorotaurine (NCT) in combination with NH4Cl against Trichomonas vaginalis.

Int J Antimicrob Agents 2011 Feb 11;37(2):171-3. Epub 2010 Nov 11.

Institute of Specific Prophylaxis and Tropical Medicine, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.1016/j.ijantimicag.2010.09.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3030749PMC
February 2011

High antitrypanosomal activity of plant-derived sulphur-containing amides.

Int J Antimicrob Agents 2010 Dec 19;36(6):570-2. Epub 2010 Sep 19.

Institute of Specific Prophylaxis and Tropical Medicine, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, Kinderspitalgasse 15, A-1090 Vienna, Austria.

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http://dx.doi.org/10.1016/j.ijantimicag.2010.07.003DOI Listing
December 2010

Proteomic aspects of Parachlamydia acanthamoebae infection in Acanthamoeba spp.

ISME J 2010 Nov 20;4(11):1366-74. Epub 2010 May 20.

Department of Specific Prophylaxis and Tropical Medicine at the Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, Kinderspitalgasse 15, Vienna A-1090, Austria.

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http://dx.doi.org/10.1038/ismej.2010.68DOI Listing
November 2010

The flavin inhibitor diphenyleneiodonium renders Trichomonas vaginalis resistant to metronidazole, inhibits thioredoxin reductase and flavin reductase, and shuts off hydrogenosomal enzymatic pathways.

Mol Biochem Parasitol 2010 May 20;171(1):17-24. Epub 2010 Jan 20.

Department of Specific Prophylaxis and Tropical Medicine at the Center for Physiology, Pathophysiology and Immunology, Medical University of Vienna, A-1090 Vienna, Austria.

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http://dx.doi.org/10.1016/j.molbiopara.2010.01.001DOI Listing
May 2010

Major role for cysteine proteases during the early phase of Acanthamoeba castellanii encystment.

Eukaryot Cell 2010 Apr 26;9(4):611-8. Epub 2010 Feb 26.

Department of Specific Prophylaxis and Tropical Medicine, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.1128/EC.00300-09DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2863413PMC
April 2010

Development of a pharmacodynamic screening model with Entamoeba histolytica.

Wien Klin Wochenschr 2007 ;119(19-20 Suppl 3):88-95

Institute for Specific Prophylaxis und Tropical Medicine, Center for Physiology und Pathophysiology, Medical University of Vienna, Vienna, Austria.

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http://link.springer.com/10.1007/s00508-007-0874-4
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http://dx.doi.org/10.1007/s00508-007-0874-4DOI Listing
February 2010

Acanthamoeba castellanii : growth on human cell layers reactivates attenuated properties after prolonged axenic culture.

FEMS Microbiol Lett 2009 Oct 5;299(2):121-7. Epub 2009 Jun 5.

Department of Medical Parasitology, Clinical Institute of Hygiene and Medical Microbiology, Medical University of Vienna, Kinderspitalgasse 15, Vienna, Austria.

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http://dx.doi.org/10.1111/j.1574-6968.2009.01680.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2810444PMC
October 2009

Anti-acanthamoeba efficacy and toxicity of miltefosine in an organotypic skin equivalent.

J Antimicrob Chemother 2009 Sep 23;64(3):539-45. Epub 2009 Jun 23.

Department of Medical Parasitology, Institute of Hygiene, Medical University of Vienna, 1095 Vienna, Austria.

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http://dx.doi.org/10.1093/jac/dkp215DOI Listing
September 2009

Trichomonas vaginalis: metronidazole and other nitroimidazole drugs are reduced by the flavin enzyme thioredoxin reductase and disrupt the cellular redox system. Implications for nitroimidazole toxicity and resistance.

Mol Microbiol 2009 Apr;72(2):518-36

Department of Specific Prophylaxis and Tropical Medicine at the Center for Physiology, Pathophysiology and Immunology, Medical University of Vienna, Vienna, Austria.

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April 2009

Entamoeba histolytica: response of the parasite to metronidazole challenge on the levels of mRNA and protein expression.

Exp Parasitol 2008 Dec 26;120(4):403-10. Epub 2008 Sep 26.

Department of Specific Prophylaxis and Tropical Medicine, Center for Physiology, Pathophysiology and Immunology, Medical University of Vienna, Kinderspitalgasse 15, A-1090 Vienna, Austria.

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http://dx.doi.org/10.1016/j.exppara.2008.09.011DOI Listing
December 2008

Acanthamoeba strains lose their abilities to encyst synchronously upon prolonged axenic culture.

Parasitol Res 2008 Apr 5;102(5):1069-72. Epub 2008 Feb 5.

Department of Medical Parasitology, Clinical Institute of Hygiene and Medical Microbiology, Medical University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.1007/s00436-008-0885-8DOI Listing
April 2008

Comparison of the proteome profiles of Entamoeba histolytica and its close but non-pathogenic relative Entamoeba dispar.

Wien Klin Wochenschr 2006 ;118(19-20 Suppl 3):37-41

Department of Specific Prophylaxis and Tropical Medicine, Center for Physiology and Pathophysiology, Medical University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.1007/s00508-006-0675-1DOI Listing
August 2007

Nitroimidazole action in Entamoeba histolytica: a central role for thioredoxin reductase.

PLoS Biol 2007 Aug;5(8):e211

Department of Specific Prophylaxis and Tropical Medicine, Center for Physiology and Pathophysiology, Medical University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.1371/journal.pbio.0050211DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1933457PMC
August 2007

Entamoeba histolytica: construction and applications of subgenomic databases.

Exp Parasitol 2005 Jul 22;110(3):178-83. Epub 2005 Apr 22.

Department of Specific Prophylaxis and Tropical Medicine, Center for Physiology and Pathophysiology, Medical University of Vienna, Kinderspitalgasse 15, A-1095 Vienna, Austria.

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http://dx.doi.org/10.1016/j.exppara.2005.03.018DOI Listing
July 2005

Entamoeba histolytica: analysis of the trophozoite proteome by two-dimensional polyacrylamide gel electrophoresis.

Exp Parasitol 2005 Jul 7;110(3):191-5. Epub 2005 Apr 7.

Department of Specific Prophylaxis and Tropical Medicine, Center for Physiology and Pathophysiology, Kinderspitalg. 15, A-1095 Vienna, Austria.

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http://dx.doi.org/10.1016/j.exppara.2005.02.016DOI Listing
July 2005

Association of autoantibodies against small nuclear ribonucleoproteins (snRNPs) with symptomatic Toxocara canis infestation.

Parasite Immunol 2004 Aug-Sep;26(8-9):327-33

Department of Medical Parasitology, Clinical Institute of Hygiene and Medical Microbiology, Medical University of Vienna, Austria.

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http://dx.doi.org/10.1111/j.0141-9838.2004.00716.xDOI Listing
April 2005

[Treatment of Acanthamoeba keratitis: possibilities, problems, and new approaches].

Wien Klin Wochenschr 2003 ;115 Suppl 3:10-7

Abteilung fur Medizinische Parasitologie, Klinisches Institut fur Hygiene und Medizinische Mikrobiologie, Wien, Osterreich.

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December 2004

Entamoeba histolytica trophozoites transfer lipophosphopeptidoglycans to enteric cell layers.

Int J Parasitol 2004 Apr;34(5):549-56

Laboratory of Experimental Cancerology, Ghent University Hospital, De Pintelaan 185, 9000 Ghent, Belgium.

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http://dx.doi.org/10.1016/j.ijpara.2003.11.013DOI Listing
April 2004

Humoral immune response against proteophosphoglycan surface antigens of Entamoeba histolytica elicited by immunization with synthetic mimotope peptides.

FEMS Immunol Med Microbiol 2003 Jul;37(2-3):179-83

Division of Specific Prophylaxis and Tropical Medicine, Department of Pathophysiology, University of Vienna, 1090 Vienna, Austria.

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http://dx.doi.org/10.1016/S0928-8244(03)00074-9DOI Listing
July 2003

Antiprotozoal activities of phospholipid analogues.

Mol Biochem Parasitol 2003 Feb;126(2):165-72

Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, UK.

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February 2003

Cytotoxic activities of alkylphosphocholines against clinical isolates of Acanthamoeba spp.

Antimicrob Agents Chemother 2002 Mar;46(3):695-701

Department of Medical Parasitology, Clinical Institute of Hygiene, University of Vienna, Vienna, Austria.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC127497PMC
http://dx.doi.org/10.1128/aac.46.3.695-701.2002DOI Listing
March 2002