Dr. Michael DiDonato, PhD - Genomics Institute of the Novartis Research Foundation (GNF) - Senior Investigator I

Dr. Michael DiDonato

PhD

Genomics Institute of the Novartis Research Foundation (GNF)

Senior Investigator I

San Diego, California | United States

Main Specialties: Biology, Biotechnology, Chemistry, Infectious Disease

ORCID logohttps://orcid.org/0000-0002-9074-7284

Dr. Michael DiDonato, PhD - Genomics Institute of the Novartis Research Foundation (GNF) - Senior Investigator I

Dr. Michael DiDonato

PhD

Introduction

Primary Affiliation: Genomics Institute of the Novartis Research Foundation (GNF) - San Diego, California , United States

Specialties:

Education

Jan 2003
The Scripps Research Institute
Postdoc
Structural Biology, 1999-2003
Sep 1999
University of Toronto
PhD
Biochemistry, Bioinorganic Chemistry
Apr 1994
University of Toronto
BSc
Combined specialist in chemistry and biochemistry.

Publications

39Publications

1787Reads

123Profile Views

Tuning a Protein-Labeling Reaction to Achieve Highly Site Selective Lysine Conjugation.

Chembiochem 2018 04 15;19(8):799-804. Epub 2018 Mar 15.

Genomics Institute of the Novartis Research Foundation (GNF), Biotherapeutics & Biotechnology, 10675 John Jay Hopkins Drive, San Diego, CA, 92121, USA.

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http://doi.wiley.com/10.1002/cbic.201700611
Publisher Site
http://dx.doi.org/10.1002/cbic.201700611DOI Listing
April 2018
19 Reads
3.088 Impact Factor

Structural, Functional, and Immunogenic Insights on Cu,Zn Superoxide Dismutase Pathogenic Virulence Factors from Neisseria meningitidis and Brucella abortus.

J Bacteriol 2015 Dec 12;197(24):3834-47. Epub 2015 Oct 12.

Department of Integrative Structural and Computational Biology and The Skaggs Institute for Chemical Biology, The Scripps Research Institute, La Jolla, California, USA

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http://jb.asm.org/lookup/doi/10.1128/JB.00343-15
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http://dx.doi.org/10.1128/JB.00343-15DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4652047PMC
December 2015
14 Reads
2.808 Impact Factor

IL-2 immunotherapy reveals potential for innate beta cell regeneration in the non-obese diabetic mouse model of autoimmune diabetes.

PLoS One 2013 24;8(10):e78483. Epub 2013 Oct 24.

Genetics Department, Genomics Institute of the Novartis Research Foundation, San Diego, California, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0078483PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3813455PMC
February 2015
30 Reads
3.234 Impact Factor

Superoxide dismutase from the eukaryotic thermophile Alvinella pompejana: structures, stability, mechanism, and insights into amyotrophic lateral sclerosis.

J Mol Biol 2009 Feb 25;385(5):1534-55. Epub 2008 Nov 25.

Department of Molecular Biology, The Skaggs Institute for Chemical Biology, The Scripps Research Institute, La Jolla, CA 92037, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S002228360801457
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http://dx.doi.org/10.1016/j.jmb.2008.11.031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2669833PMC
February 2009
9 Reads
4.333 Impact Factor

A scaleable and integrated crystallization pipeline applied to mining the Thermotoga maritima proteome.

J Struct Funct Genomics 2004 ;5(1-2):133-46

The Joint Center for Structural Genomics, and The Genomics Institute of the Novartis Research Foundation, 10675 John Jay Hopkins Drive, San Diego, CA 92121, USA.

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http://dx.doi.org/10.1023/B:JSFG.0000029194.04443.50DOI Listing
November 2004

ALS mutants of human superoxide dismutase form fibrous aggregates via framework destabilization.

J Mol Biol 2003 Sep;332(3):601-15

Department of Molecular Biology, The Skaggs Institute for Chemical Biology, The Scripps Research Institute, Maildrop MB4, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA.

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http://dx.doi.org/10.1016/s0022-2836(03)00889-1DOI Listing
September 2003
2 Reads
4.333 Impact Factor

Insights into Lou Gehrig's disease from the structure and instability of the A4V mutant of human Cu,Zn superoxide dismutase.

J Mol Biol 2002 Nov;324(2):247-56

Department of Molecular Biology and Skaggs Institute for Chemical Biology, The Scripps Research Institute, Maildrop MB4, 10550 North Torrey Pines Road, La Jolla, CA 92037-1027, USA.

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http://dx.doi.org/10.1016/s0022-2836(02)01090-2DOI Listing
November 2002
4 Reads
4.333 Impact Factor

Zinc binding to the NH2-terminal domain of the Wilson disease copper-transporting ATPase: implications for in vivo metal ion-mediated regulation of ATPase activity.

J Biol Chem 2002 Apr 31;277(16):13409-14. Epub 2002 Jan 31.

Department of Structural Biology and Biochemistry, The Hospital for Sick Children, Toronto, Ontario M5G 1X8, Canada.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M111649200
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http://dx.doi.org/10.1074/jbc.M111649200DOI Listing
April 2002
2 Reads
4.573 Impact Factor