Publications by authors named "Michael Dewaele"

18Publications

p38(MAPK)-regulated induction of p62 and NBR1 after photodynamic therapy promotes autophagic clearance of ubiquitin aggregates and reduces reactive oxygen species levels by supporting Nrf2-antioxidant signaling.

Free Radic Biol Med 2014 Feb 22;67:292-303. Epub 2013 Nov 22.

Cell Death Research & Therapy Laboratory, Cellular and Molecular Medicine Department, KU Leuven - University of Leuven, 3000 Leuven, Belgium. Electronic address:

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http://dx.doi.org/10.1016/j.freeradbiomed.2013.11.010DOI Listing
February 2014

Pro-apoptotic signaling induced by photo-oxidative ER stress is amplified by Noxa, not Bim.

Biochem Biophys Res Commun 2013 Aug 2;438(3):500-6. Epub 2013 Aug 2.

Laboratory of Cell Death Research and Therapy, Department of Cellular and Molecular Medicine, KU Leuven, Belgium.

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http://dx.doi.org/10.1016/j.bbrc.2013.07.107DOI Listing
August 2013

MDM4 is a key therapeutic target in cutaneous melanoma.

Nat Med 2012 Aug 22;18(8):1239-47. Epub 2012 Jul 22.

Center for the Biology of Disease, Laboratory for Molecular Cancer Biology, Vlaams Instituut voor Biotechnologie (VIB), Leuven, Belgium; Center for Human Genetics, Katholieke Universiteit (KU) Leuven, Leuven, Belgium.

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http://dx.doi.org/10.1038/nm.2863DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3744207PMC
August 2012

Ins(1,4,5)P3 receptor-mediated Ca2+ signaling and autophagy induction are interrelated.

Autophagy 2011 Dec;7(12):1472-89

Laboratory of Molecular and Cellular Signaling, Department Molecular Cell Biology, K.U. Leuven, Campus Gasthuisberg, Leuven, Belgium.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3327615PMC
http://dx.doi.org/10.4161/auto.7.12.17909DOI Listing
December 2011

NF-kappaB inhibition improves the sensitivity of human glioblastoma cells to 5-aminolevulinic acid-based photodynamic therapy.

Biochem Pharmacol 2011 Mar 21;81(5):606-16. Epub 2010 Dec 21.

Virology and Immunology Unit, GIGA-R, GIGA B34, University of Liège, Liège Belgium.

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http://dx.doi.org/10.1016/j.bcp.2010.12.015DOI Listing
March 2011

Autophagy pathways activated in response to PDT contribute to cell resistance against ROS damage.

J Cell Mol Med 2011 Jun 7;15(6):1402-14. Epub 2010 Jul 7.

Cell Death Research and Therapy Laboratory, Department of Molecular Cell Biology, Faculty of Medicine, Katholieke Universiteit Leuven, Leuven, Belgium.

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http://dx.doi.org/10.1111/j.1582-4934.2010.01118.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4373339PMC
June 2011

Death and survival signals in photodynamic therapy.

Methods Mol Biol 2010 ;635:7-33

Department of Molecular and Cell Biology, Catholic University of Leuven, Leuven, Belgium.

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http://dx.doi.org/10.1007/978-1-60761-697-9_2DOI Listing
September 2010

ROS-mediated mechanisms of autophagy stimulation and their relevance in cancer therapy.

Autophagy 2010 Oct 19;6(7):838-54. Epub 2010 Oct 19.

Cell Death Research and Therapy Laboratory, Department of Molecular Cell Biology, Faculty of Medicine, Katholieke Universiteit Leuven, Belgium.

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http://dx.doi.org/10.4161/auto.6.7.12113DOI Listing
October 2010

Autophagy in disease: a double-edged sword with therapeutic potential.

Clin Sci (Lond) 2009 May;116(9):697-712

Division of Pharmacology, University of Antwerp, B-2610 Antwerp, Belgium.

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http://clinsci.org/lookup/doi/10.1042/CS20080508
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http://dx.doi.org/10.1042/CS20080508DOI Listing
May 2009

Molecular effectors of multiple cell death pathways initiated by photodynamic therapy.

Biochim Biophys Acta 2007 Sep 6;1776(1):86-107. Epub 2007 Jul 6.

Department of Molecular and Cell Biology, Faculty of Medicine, Catholic University of Leuven, Campus Gasthuisberg, Herestraat 49, B-3000, Leuven Belgium.

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http://dx.doi.org/10.1016/j.bbcan.2007.07.001DOI Listing
September 2007

Targeted inhibition of p38alpha MAPK suppresses tumor-associated endothelial cell migration in response to hypericin-based photodynamic therapy.

Biochem Biophys Res Commun 2005 Nov 30;337(3):928-35. Epub 2005 Sep 30.

Department Molecular and Cell Biology, Catholic University of Leuven, Leuven, Belgium.

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http://dx.doi.org/10.1016/j.bbrc.2005.09.135DOI Listing
November 2005