Michael D Wilson

Michael D Wilson

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Michael D Wilson

Michael D Wilson

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Pharmacoinformatics-based identification of potential bioactive compounds against Ebola virus protein VP24.

Authors:
Samuel K Kwofie Emmanuel Broni Joshua Teye Erasmus Quansah Ibrahim Issah Michael D Wilson Whelton A Miller Elvis K Tiburu Joseph H K Bonney

Comput Biol Med 2019 Oct 28;113:103414. Epub 2019 Aug 28.

Department of Virology, Noguchi Memorial Institute for Medical Research (NMIMR), College of Health Sciences (CHS), University of Ghana, P.O. Box LG 581, Legon, Accra, Ghana.

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https://linkinghub.elsevier.com/retrieve/pii/S00104825193029
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http://dx.doi.org/10.1016/j.compbiomed.2019.103414DOI Listing
October 2019

Sufu- and Spop-mediated downregulation of Hedgehog signaling promotes beta cell differentiation through organ-specific niche signals.

Authors:
Theodora Yung Frankie Poon Minggao Liang Sabrina Coquenlorge Emily C McGaugh Chi-Chung Hui Michael D Wilson M Cristina Nostro Tae-Hee Kim

Nat Commun 2019 Oct 11;10(1):4647. Epub 2019 Oct 11.

Program in Developmental & Stem Cell Biology, The Hospital for Sick Children, Toronto, Ontario, M5G 0A4, Canada.

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http://dx.doi.org/10.1038/s41467-019-12624-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6789033PMC
October 2019

Levels of serum eosinophil cationic protein are associated with hookworm infection and intensity in endemic communities in Ghana.

Authors:
Benjamin Amoani Bright Adu Margaret T Frempong Tracy Sarkodie-Addo Samuel Victor Nuvor Michael D Wilson Ben Gyan

PLoS One 2019 12;14(9):e0222382. Epub 2019 Sep 12.

Department of Immunology, Noguchi Memorial Institute for Medical Research, College of Health Sciences, University of Ghana, Legon, Ghana.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0222382PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6742367PMC
September 2019

Regulation of expression in human vascular endothelial cells by a neighboring divergently transcribed long noncoding RNA.

Authors:
Nadiya Khyzha Melvin Khor Peter V DiStefano Liangxi Wang Ljubica Matic Ulf Hedin Michael D Wilson Lars Maegdefessel Jason E Fish

Proc Natl Acad Sci U S A 2019 Aug 26;116(33):16410-16419. Epub 2019 Jul 26.

Toronto General Hospital Research Institute, University Health Network, Toronto, ON M5G 2C4, Canada;

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http://dx.doi.org/10.1073/pnas.1904108116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6697820PMC
August 2019

Break Check: Transcription-Driven Topoisomerase II Collisions near Chromatin Loop Anchors Are Hotspots for DNA Damage and Translocations.

Authors:
Liis Uusküla-Reimand Michael D Wilson

Mol Cell 2019 Jul;75(2):203-205

Genetics and Genome Biology Program, SickKids Research Institute, Toronto, ON, Canada; Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.molcel.2019.07.003DOI Listing
July 2019

Molecular Informatics Studies of the Iron-Dependent Regulator (ideR) Reveal Potential Novel Anti- Natural Product-Derived Compounds.

Authors:
Samuel K Kwofie Kweku S Enninful Jaleel A Yussif Lina A Asante Mavis Adjei Kwabena Kan-Dapaah Elvis K Tiburu Wilhelmina A Mensah Whelton A Miller Lydia Mosi Michael D Wilson

Molecules 2019 Jun 21;24(12). Epub 2019 Jun 21.

Department of Medicine, Loyola University Medical Center, Maywood, IL 60153, USA.

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http://dx.doi.org/10.3390/molecules24122299DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6631925PMC
June 2019

The long road home from distraction: Investigating the time-course of distraction recovery in driving.

Authors:
Vanessa K Bowden Shayne Loft Michael D Wilson James Howard Troy A W Visser

Accid Anal Prev 2019 Mar 2;124:23-32. Epub 2019 Jan 2.

University of Western Australia, Australia.

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http://dx.doi.org/10.1016/j.aap.2018.12.012DOI Listing
March 2019

Assessing the Presence of Infections in Vectors Using Xenomonitoring in Lymphatic Filariasis Endemic Districts in Ghana.

Authors:
Sellase Pi-Bansa Joseph H N Osei Worlasi D Kartey-Attipoe Elizabeth Elhassan David Agyemang Sampson Otoo Samuel K Dadzie Maxwell A Appawu Michael D Wilson Benjamin G Koudou Dziedzom K de Souza Jürg Utzinger Daniel A Boakye

Trop Med Infect Dis 2019 Mar 17;4(1). Epub 2019 Mar 17.

Noguchi Memorial Institute for Medical Research, College of Health Sciences, University of Ghana, LG 581 Legon, Ghana.

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http://dx.doi.org/10.3390/tropicalmed4010049DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6473662PMC
March 2019

Molecular Docking and Dynamics Simulation Studies Predict Munc18b as a Target of Mycolactone: A Plausible Mechanism for Granule Exocytosis Impairment in Buruli Ulcer Pathogenesis.

Authors:
Samuel K Kwofie Bismark Dankwa Kweku S Enninful Courage Adobor Emmanuel Broni Alfred Ntiamoah Michael D Wilson

Toxins (Basel) 2019 03 25;11(3). Epub 2019 Mar 25.

Department of Parasitology, Noguchi Memorial Institute for Medical Research, University of Ghana, P.O. Box LG 581, Legon, Accra, Ghana.

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https://www.mdpi.com/2072-6651/11/3/181
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http://dx.doi.org/10.3390/toxins11030181DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6468854PMC
March 2019

Interactome Rewiring Following Pharmacological Targeting of BET Bromodomains.

Authors:
Jean-Philippe Lambert Sarah Picaud Takao Fujisawa Huayun Hou Pavel Savitsky Liis Uusküla-Reimand Gagan D Gupta Hala Abdouni Zhen-Yuan Lin Monika Tucholska James D R Knight Beatriz Gonzalez-Badillo Nicole St-Denis Joseph A Newman Manuel Stucki Laurence Pelletier Nuno Bandeira Michael D Wilson Panagis Filippakopoulos Anne-Claude Gingras

Mol Cell 2019 02 13;73(3):621-638.e17. Epub 2018 Dec 13.

Lunenfeld-Tanenbaum Research Institute at Mount Sinai Hospital, Toronto, ON M5G 1X5, Canada; Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S10972765183094
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http://dx.doi.org/10.1016/j.molcel.2018.11.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6375729PMC
February 2019

Genetic Markers of Benzimidazole Resistance among Human Hookworms () in Kintampo North Municipality, Ghana.

Authors:
Ambrose R Orr Josephine E Quagraine Peter Suwondo Santosh George Lisa M Harrison Fabio Pio Dornas Benjamin Evans Adalgisa Caccone Debbie Humphries Michael D Wilson Michael Cappello

Am J Trop Med Hyg 2019 02;100(2):351-356

Yale Partnerships for Global Health, Department of Pediatrics, Yale School of Medicine, New Haven, Connecticut.

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http://dx.doi.org/10.4269/ajtmh.18-0727DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6367626PMC
February 2019

Evaluating Academic Mentorship Programs in Low- and Middle-Income Country Institutions: Proposed Framework and Metrics.

Authors:
Benjamin H Chi Jose M Belizan Magaly M Blas Alice Chuang Michael D Wilson Carla J Chibwesha Carey Farquhar Craig R Cohen Tony Raj

Am J Trop Med Hyg 2019 01;100(1_Suppl):36-41

St. John's Research Institute, Bengaluru, India.

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http://www.ajtmh.org/content/journals/10.4269/ajtmh.18-0561
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http://dx.doi.org/10.4269/ajtmh.18-0561DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6329356PMC
January 2019

Dual Regulatory Functions of SUFU and Targetome of GLI2 in SHH Subgroup Medulloblastoma.

Authors:
Wen-Chi Yin Thevagi Satkunendran Rong Mo Sorana Morrissy Xiaoyun Zhang Eunice Shiao Huang Liis Uusküla-Reimand Huayun Hou Joe Eun Son Weifan Liu Yulu C Liu Jianing Zhang Jessica Parker Xin Wang Hamza Farooq Hayden Selvadurai Xin Chen Elly Sau-Wai Ngan Steven Y Cheng Peter B Dirks Stephane Angers Michael D Wilson Michael D Taylor Chi-Chung Hui

Dev Cell 2019 01 13;48(2):167-183.e5. Epub 2018 Dec 13.

Program in Developmental & Stem Cell Biology, The Hospital for Sick Children, Toronto, ON, Canada; Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada; Joint Institute of Genetics and Genomic Medicine, Zhejiang University and University of Toronto, Toronto, ON, Canada. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S15345807183093
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http://dx.doi.org/10.1016/j.devcel.2018.11.015DOI Listing
January 2019

Hey2 regulates the size of the cardiac progenitor pool during vertebrate heart development.

Authors:
Natalie Gibb Savo Lazic Xuefei Yuan Ashish R Deshwar Meaghan Leslie Michael D Wilson Ian C Scott

Development 2018 11 21;145(22). Epub 2018 Nov 21.

Program in Developmental and Stem Cell Biology, The Hospital for Sick Children, Toronto, Ontario M5G 0A4, Canada

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http://dx.doi.org/10.1242/dev.167510DOI Listing
November 2018

Heart enhancers with deeply conserved regulatory activity are established early in zebrafish development.

Authors:
Xuefei Yuan Mengyi Song Patrick Devine Benoit G Bruneau Ian C Scott Michael D Wilson

Nat Commun 2018 11 26;9(1):4977. Epub 2018 Nov 26.

Program in Genetics and Genome Biology, The Hospital for Sick Children, Toronto, ON, M5G 0A4, Canada.

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http://dx.doi.org/10.1038/s41467-018-07451-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6255839PMC
November 2018

Single cell RNA sequencing of human liver reveals distinct intrahepatic macrophage populations.

Authors:
Sonya A MacParland Jeff C Liu Xue-Zhong Ma Brendan T Innes Agata M Bartczak Blair K Gage Justin Manuel Nicholas Khuu Juan Echeverri Ivan Linares Rahul Gupta Michael L Cheng Lewis Y Liu Damra Camat Sai W Chung Rebecca K Seliga Zigong Shao Elizabeth Lee Shinichiro Ogawa Mina Ogawa Michael D Wilson Jason E Fish Markus Selzner Anand Ghanekar David Grant Paul Greig Gonzalo Sapisochin Nazia Selzner Neil Winegarden Oyedele Adeyi Gordon Keller Gary D Bader Ian D McGilvray

Nat Commun 2018 10 22;9(1):4383. Epub 2018 Oct 22.

Multi-Organ Transplant Program, Toronto General Hospital Research Institute, Toronto, ON, M5G 2C4, Canada.

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http://dx.doi.org/10.1038/s41467-018-06318-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6197289PMC
October 2018

The transcriptional regulator CCCTC-binding factor limits oxidative stress in endothelial cells.

Authors:
Anna R Roy Abdalla Ahmed Peter V DiStefano Lijun Chi Nadiya Khyzha Niels Galjart Michael D Wilson Jason E Fish Paul Delgado-Olguín

J Biol Chem 2018 06 2;293(22):8449-8461. Epub 2018 Apr 2.

From the Translational Medicine Research Program, The Hospital for Sick Children, Toronto, Ontario M5G 0A4, Canada,

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http://dx.doi.org/10.1074/jbc.M117.814699DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5986204PMC
June 2018

Screening of Isocitrate Lyase for Novel Anti-Buruli Ulcer Natural Products Originating from Africa.

Authors:
Samuel K Kwofie Bismark Dankwa Emmanuel A Odame Francis E Agamah Lady P A Doe Joshua Teye Odame Agyapong Whelton A Miller Lydia Mosi Michael D Wilson

Molecules 2018 06 27;23(7). Epub 2018 Jun 27.

Department of Parasitology, Noguchi Memorial Institute for Medical Research (NMIMR), College of Health Sciences (CHS), University of Ghana, P. O. Box LG 77, Legon, Accra, Ghana.

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http://dx.doi.org/10.3390/molecules23071550DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6100440PMC
June 2018

Twelve-month longitudinal parasitological assessment of lymphatic filariasis-positive individuals: impact of a biannual treatment with ivermectin and albendazole.

Authors:
John N Kanamitie Collins S Ahorlu Joseph Otchere Fred Aboagye-Antwi Bethel Kwansa-Bentum Daniel A Boakye Nana-Kwadwo Biritwum Michael D Wilson Dziedzom K de Souza

Trop Med Int Health 2017 11 26;22(11):1451-1456. Epub 2017 Sep 26.

Department of Parasitology, Noguchi Memorial Institute for Medical Research, University of Ghana, Accra, Ghana.

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http://dx.doi.org/10.1111/tmi.12974DOI Listing
November 2017

The Role of Detoxification Enzymes in the Adaptation of the Major Malaria Vector Anopheles gambiae (Giles; Diptera: Culicidae) to Polluted Water.

Authors:
Sandra A King Bibian Onayifeke Jewelna Akorli Isaie Sibomana Joseph Chabi Theresa Manful-Gwira Samuel Dadzie Takashi Suzuki Michael D Wilson Daniel A Boakye Dziedzom K de Souza

J Med Entomol 2017 11;54(6):1674-1683

Parasitology Department, Noguchi Memorial Institute for Medical Research, University of Ghana, Legon-Accra, Ghana.

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http://dx.doi.org/10.1093/jme/tjx164DOI Listing
November 2017

Cross-Cancer Analysis Reveals Novel Pleiotropic Associations-Response.

Authors:
Rayjean J Hung Gordon Fehringer Graham Casey Stephen B Gruber Ulrike Peters Ellen L Goode Thomas A Sellers Christopher A Haiman David J Hunter Peter Kraft Christopher I Amos Matthew L Freedman Michael D Wilson

Cancer Res 2017 11 24;77(21):6045-6046. Epub 2017 Oct 24.

Hospital of Sick Children, Toronto, Canada.

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http://dx.doi.org/10.1158/0008-5472.CAN-17-1584DOI Listing
November 2017

The duplication mutation of Quebec platelet disorder dysregulates PLAU, but not C10orf55, selectively increasing production of normal PLAU transcripts by megakaryocytes but not granulocytes.

Authors:
Catherine P M Hayward Minggao Liang Subia Tasneem Asim Soomro John S Waye Andrew D Paterson Georges E Rivard Michael D Wilson

PLoS One 2017 16;12(3):e0173991. Epub 2017 Mar 16.

Genetics and Genome Biology, The Hospital for Sick Children, Toronto, ON, Canada.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0173991PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5354430PMC
September 2017

Sex-specific effect of CPB2 Ala147Thr but not Thr325Ile variants on the risk of venous thrombosis: A comprehensive meta-analysis.

Authors:
Nora Zwingerman Alejandra Medina-Rivera Irfahan Kassam Michael D Wilson Pierre-Emmanuel Morange David-Alexandre Trégouët France Gagnon

PLoS One 2017 26;12(5):e0177768. Epub 2017 May 26.

Division of Epidemiology, Dalla Lana School of Public Health, University of Toronto, Toronto, Canada.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0177768PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5446132PMC
September 2017

Gene expression profiling of puberty-associated genes reveals abundant tissue and sex-specific changes across postnatal development.

Authors:
Huayun Hou Liis Uusküla-Reimand Maisam Makarem Christina Corre Shems Saleh Ariane Metcalf Anna Goldenberg Mark R Palmert Michael D Wilson

Hum Mol Genet 2017 09;26(18):3585-3599

Program in Genetics and Genome Biology, Research Institute, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada.

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http://dx.doi.org/10.1093/hmg/ddx246DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5886205PMC
September 2017

Experimental demonstration of the possible role of Acanthamoeba polyphaga in the infection and disease progression in Buruli Ulcer (BU) using ICR mice.

Authors:
Bright K Azumah Phyllis G Addo Alfred Dodoo Gordon Awandare Lydia Mosi Daniel A Boakye Michael D Wilson

PLoS One 2017 22;12(3):e0172843. Epub 2017 Mar 22.

Department of Parasitology, Noguchi Memorial Institute for Medical Research, University of Ghana, Legon, Accra, Ghana.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0172843PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5362167PMC
August 2017

Correction of a splicing defect in a mouse model of congenital muscular dystrophy type 1A using a homology-directed-repair-independent mechanism.

Authors:
Dwi U Kemaladewi Eleonora Maino Elzbieta Hyatt Huayun Hou Maylynn Ding Kara M Place Xinyi Zhu Prabhpreet Bassi Zahra Baghestani Amit G Deshwar Daniele Merico Hui Y Xiong Brendan J Frey Michael D Wilson Evgueni A Ivakine Ronald D Cohn

Nat Med 2017 Aug 17;23(8):984-989. Epub 2017 Jul 17.

Program in Genetics and Genome Biology, The Hospital for Sick Children Research Institute, Toronto, Canada.

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http://www.nature.com/doifinder/10.1038/nm.4367
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http://dx.doi.org/10.1038/nm.4367DOI Listing
August 2017

Seasonality and Locality Affect the Diversity of Anopheles gambiae and Anopheles coluzzii Midgut Microbiota from Ghana.

Authors:
Jewelna Akorli Mathilde Gendrin Nana Adjoa P Pels Dorothy Yeboah-Manu George K Christophides Michael D Wilson

PLoS One 2016 20;11(6):e0157529. Epub 2016 Jun 20.

Department of Parasitology, Noguchi Memorial Institute for Medical Research, College of Health Sciences, University of Ghana, P.O. Box LG 581, Legon, Accra, Ghana.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0157529PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4913965PMC
July 2017

Leveraging cell type specific regulatory regions to detect SNPs associated with tissue factor pathway inhibitor plasma levels.

Authors:
Jessica Dennis Alejandra Medina-Rivera Vinh Truong Lina Antounians Nora Zwingerman Giovana Carrasco Lisa Strug Phil Wells David-Alexandre Trégouët Pierre-Emmanuel Morange Michael D Wilson France Gagnon

Genet Epidemiol 2017 07 18;41(5):455-466. Epub 2017 Apr 18.

Dalla Lana School of Public Health, University of Toronto, Toronto, Canada.

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http://dx.doi.org/10.1002/gepi.22049DOI Listing
July 2017

Dynamic regulation of VEGF-inducible genes by an ERK/ERG/p300 transcriptional network.

Authors:
Jason E Fish Manuel Cantu Gutierrez Lan T Dang Nadiya Khyzha Zhiqi Chen Shawn Veitch Henry S Cheng Melvin Khor Lina Antounians Makon-Sébastien Njock Emilie Boudreau Alexander M Herman Alexander M Rhyner Oscar E Ruiz George T Eisenhoffer Alejandra Medina-Rivera Michael D Wilson Joshua D Wythe

Development 2017 07 23;144(13):2428-2444. Epub 2017 May 23.

Cardiovascular Research Institute, Baylor College of Medicine, Houston, TX 77030, USA

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http://dx.doi.org/10.1242/dev.146050DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5536864PMC
July 2017

G9a controls placental vascular maturation by activating the Notch Pathway.

Authors:
Lijun Chi Abdalla Ahmed Anna R Roy Sandra Vuong Lindsay S Cahill Laura Caporiccio John G Sled Isabella Caniggia Michael D Wilson Paul Delgado-Olguin

Development 2017 06 28;144(11):1976-1987. Epub 2017 Apr 28.

Translational Medicine, The Hospital for Sick Children, Toronto, Ontario M5G 0A4, Canada

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http://dx.doi.org/10.1242/dev.148916DOI Listing
June 2017

A de novo deletion in a boy with cerebral palsy suggests a refined critical region for the 4q21.22 microdeletion syndrome.

Authors:
Mehdi Zarrei Daniele Merico Barbara Kellam Worrawat Engchuan Tara Scriver Rikash Jokhan Michael D Wilson Jeremy Parr Edmond G Lemire Dimitri J Stavropoulos Stephen W Scherer

Am J Med Genet A 2017 May 3;173(5):1287-1293. Epub 2017 Apr 3.

The Centre for Applied Genomics and Program in Genetics and Genome Biology, The Hospital for Sick Children, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1002/ajmg.a.38176DOI Listing
May 2017

The Genomic Architecture of Novel Prophage Sequence Elements and Implications for Onchocerciasis Epidemiology.

Authors:
James L Crainey Jacob Hurst Poppy H L Lamberton Robert A Cheke Claire E Griffin Michael D Wilson Cláudia P Mendes de Araújo María-Gloria Basáñez Rory J Post

Front Microbiol 2017 29;8:852. Epub 2017 May 29.

School of Natural Sciences and Psychology, Liverpool John Moores UniversityLiverpool, UK.

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http://dx.doi.org/10.3389/fmicb.2017.00852DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5447182PMC
May 2017

Epigenetics of Atherosclerosis: Emerging Mechanisms and Methods.

Authors:
Nadiya Khyzha Azad Alizada Michael D Wilson Jason E Fish

Trends Mol Med 2017 04 11;23(4):332-347. Epub 2017 Mar 11.

Toronto General Hospital Research Institute, University Health Network, Toronto, Canada; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Canada; Heart & Stroke Richard Lewar Centre of Excellence in Cardiovascular Research, Toronto, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.molmed.2017.02.004DOI Listing
April 2017

CpG Methylation, a Parent-of-Origin Effect for Maternal-Biased Transmission of Congenital Myotonic Dystrophy.

Authors:
Lise Barbé Stella Lanni Arturo López-Castel Silvie Franck Claudia Spits Kathelijn Keymolen Sara Seneca Stephanie Tomé Ioana Miron Julie Letourneau Minggao Liang Sanaa Choufani Rosanna Weksberg Michael D Wilson Zdenek Sedlacek Cynthia Gagnon Zuzana Musova David Chitayat Patrick Shannon Jean Mathieu Karen Sermon Christopher E Pearson

Am J Hum Genet 2017 Mar;100(3):488-505

Genetics & Genome Biology, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada; The Department of Molecular Genetics, University of Toronto, Toronto, ON M5S 1A8, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.ajhg.2017.01.033DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5339342PMC
March 2017

Characterisation of the opposing effects of G6PD deficiency on cerebral malaria and severe malarial anaemia.

Authors:
Geraldine M Clarke Kirk Rockett Katja Kivinen Christina Hubbart Anna E Jeffreys Kate Rowlands Muminatou Jallow David J Conway Kalifa A Bojang Margaret Pinder Stanley Usen Fatoumatta Sisay-Joof Giorgio Sirugo Ousmane Toure Mahamadou A Thera Salimata Konate Sibiry Sissoko Amadou Niangaly Belco Poudiougou Valentina D Mangano Edith C Bougouma Sodiomon B Sirima David Modiano Lucas N Amenga-Etego Anita Ghansah Kwadwo A Koram Michael D Wilson Anthony Enimil Jennifer Evans Olukemi K Amodu Subulade Olaniyan Tobias Apinjoh Regina Mugri Andre Ndi Carolyne M Ndila Sophie Uyoga Alexander Macharia Norbert Peshu Thomas N Williams Alphaxard Manjurano Nuno Sepúlveda Taane G Clark Eleanor Riley Chris Drakeley Hugh Reyburn Vysaul Nyirongo David Kachala Malcolm Molyneux Sarah J Dunstan Nguyen Hoan Phu Nguyen Ngoc Quyen Cao Quang Thai Tran Tinh Hien Laurens Manning Moses Laman Peter Siba Harin Karunajeewa Steve Allen Angela Allen Timothy Me Davis Pascal Michon Ivo Mueller Síle F Molloy Susana Campino Angeliki Kerasidou Victoria J Cornelius Lee Hart Shivang S Shah Gavin Band Chris Ca Spencer Tsiri Agbenyega Eric Achidi Ogobara K Doumbo Jeremy Farrar Kevin Marsh Terrie Taylor Dominic P Kwiatkowski

Elife 2017 01 9;6. Epub 2017 Jan 9.

Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom.

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http://dx.doi.org/10.7554/eLife.15085DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5222559PMC
January 2017

Diversity in breeding sites and distribution of Anopheles mosquitoes in selected urban areas of southern Ghana.

Authors:
Precious A Dzorgbe Mattah Godfred Futagbi Leonard K Amekudzi Memuna M Mattah Dziedzorm K de Souza Worlasi D Kartey-Attipoe Langbong Bimi Michael D Wilson

Parasit Vectors 2017 01 13;10(1):25. Epub 2017 Jan 13.

Parasitology Department, Noguchi Memorial Institute of Medical Research, University of Ghana, Legon, Ghana.

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http://dx.doi.org/10.1186/s13071-016-1941-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5237286PMC
January 2017

Carriage of sub-microscopic sexual and asexual stages in the dry season at Navrongo, Ghana.

Authors:
Geoffrey R Atelu Nancy O Duah Michael D Wilson

Ghana Med J 2016 Dec;50(4):220-227

Parasitology Department, Noguchi Memorial Institute for Medical Research, University of Ghana, P. O. Box LG 581, Legon, Ghana.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5443672PMC
http://dx.doi.org/10.4314/gmj.v50i4.4DOI Listing
December 2016

Onchocerciasis transmission in Ghana: the human blood index of sibling species of the Simulium damnosum complex.

Authors:
Poppy H L Lamberton Robert A Cheke Martin Walker Peter Winskill J Lee Crainey Daniel A Boakye Mike Y Osei-Atweneboana Iñaki Tirados Michael D Wilson Anthony Tetteh-Kumah Sampson Otoo Rory J Post María-Gloria Basañez

Parasit Vectors 2016 08 5;9(1):432. Epub 2016 Aug 5.

London Centre for Neglected Tropical Disease Research, Department of Infectious Disease Epidemiology, School of Public Health, Faculty of Medicine (St Mary's campus), Imperial College London, Norfolk Place, London, W2 1PG, UK.

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http://dx.doi.org/10.1186/s13071-016-1703-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4975878PMC
August 2016

Topoisomerase II beta interacts with cohesin and CTCF at topological domain borders.

Authors:
Liis Uusküla-Reimand Huayun Hou Payman Samavarchi-Tehrani Matteo Vietri Rudan Minggao Liang Alejandra Medina-Rivera Hisham Mohammed Dominic Schmidt Petra Schwalie Edwin J Young Jüri Reimand Suzana Hadjur Anne-Claude Gingras Michael D Wilson

Genome Biol 2016 08 31;17(1):182. Epub 2016 Aug 31.

Genetics and Genome Biology Program, SickKids Research Institute, Toronto, ON, Canada.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5006368PMC
August 2016

A microRNA-328 binding site in PAX6 is associated with centrotemporal spikes of rolandic epilepsy.

Authors:
Naim Panjwani Michael D Wilson Laura Addis Jennifer Crosbie Elaine Wirrell Stéphane Auvin Roberto H Caraballo Maria Kinali David McCormick Caroline Oren Jacqueline Taylor John Trounce Tara Clarke Cigdem I Akman Steven L Kugler David E Mandelbaum Patricia McGoldrick Steven M Wolf Paul Arnold Russell Schachar Deb K Pal Lisa J Strug

Ann Clin Transl Neurol 2016 07 2;3(7):512-22. Epub 2016 Jun 2.

Program in Genetics and Genome Biology The Hospital for Sick Children Toronto Ontario M5G 0A4 Canada; Division of Biostatistics Dalla Lana School of Public Health University of Toronto Toronto Ontario M5T 3M7 Canada; The Centre for Applied Genomics The Hospital for Sick Children Toronto Ontario M5G 0A4 Canada.

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http://dx.doi.org/10.1002/acn3.320DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4931716PMC
July 2016

Decreased Transcription Factor Binding Levels Nearby Primate Pseudogenes Suggest Regulatory Degeneration.

Authors:
Gavin M Douglas Michael D Wilson Alan M Moses

Mol Biol Evol 2016 06 16;33(6):1478-85. Epub 2016 Feb 16.

Department of Ecology and Evolutionary Biology, University of Toronto, Toronto, ON, Canada Department of Cell and Systems Biology, University of Toronto, Toronto, ON, Canada

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http://dx.doi.org/10.1093/molbev/msw030DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4868113PMC
June 2016

Does Increasing Treatment Frequency Address Suboptimal Responses to Ivermectin for the Control and Elimination of River Blindness?

Authors:
Kwadwo K Frempong Martin Walker Robert A Cheke Edward Jenner Tetevi Ernest Tawiah Gyan Ebenezer O Owusu Michael D Wilson Daniel A Boakye Mark J Taylor Nana-Kwadwo Biritwum Mike Osei-Atweneboana María-Gloria Basáñez

Clin Infect Dis 2016 06 21;62(11):1338-1347. Epub 2016 Mar 21.

London Centre for Neglected Tropical Disease Research, Department of Infectious Disease Epidemiology, School of Public Health, Imperial College London.

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http://dx.doi.org/10.1093/cid/ciw144DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4872292PMC
June 2016

Assessing Lymphatic Filariasis Data Quality in Endemic Communities in Ghana, Using the Neglected Tropical Diseases Data Quality Assessment Tool for Preventive Chemotherapy.

Authors:
Dziedzom K de Souza Eric Yirenkyi Joseph Otchere Nana-Kwadwo Biritwum Donne K Ameme Samuel Sackey Collins Ahorlu Michael D Wilson

PLoS Negl Trop Dis 2016 Mar 30;10(3):e0004590. Epub 2016 Mar 30.

Parasitology Department, Noguchi Memorial Institute for Medical Research, University of Ghana, Accra, Ghana.

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http://dx.doi.org/10.1371/journal.pntd.0004590DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4814091PMC
March 2016

Insecticide susceptibility of natural populations of Anopheles coluzzii and Anopheles gambiae (sensu stricto) from Okyereko irrigation site, Ghana, West Africa.

Authors:
Joseph Chabi Philip K Baidoo Alex K Datsomor Dora Okyere Aikins Ablorde Alidu Iddrisu Michael D Wilson Samuel K Dadzie Helen P Jamet Joseph W Diclaro

Parasit Vectors 2016 Mar 31;9:182. Epub 2016 Mar 31.

Vector Biology Research Program, U.S. Naval Medical Research Unit No 3, Cairo, Egypt.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4815066PMC
March 2016

Spell Checking Nature: Versatility of CRISPR/Cas9 for Developing Treatments for Inherited Disorders.

Authors:
Daria Wojtal Dwi U Kemaladewi Zeenat Malam Sarah Abdullah Tatianna W Y Wong Elzbieta Hyatt Zahra Baghestani Sergio Pereira James Stavropoulos Vincent Mouly Kamel Mamchaoui Francesco Muntoni Thomas Voit Hernan D Gonorazky James J Dowling Michael D Wilson Roberto Mendoza-Londono Evgueni A Ivakine Ronald D Cohn

Am J Hum Genet 2016 Jan 10;98(1):90-101. Epub 2015 Dec 10.

Program in Genetics and Genome Biology, Research Institute, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada; Department of Molecular Genetics, University of Toronto, Toronto, ON M5S 1A8, Canada; Department of Paediatrics, University of Toronto, Toronto, ON M5G 1X8, Canada; Division of Clinical and Metabolic Genetics, The Hospital for Sick Children, Toronto, ON M5G 1X8, Canada; Centre for Genetic Medicine, The Hospital for Sick Children, Toronto, ON M5G 1X8, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.ajhg.2015.11.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4716669PMC
January 2016

RNAseq analysis for the diagnosis of muscular dystrophy.

Authors:
Hernan Gonorazky Minggao Liang Beryl Cummings Monkol Lek Johann Micallef Cynthia Hawkins Raveen Basran Ronald Cohn Michael D Wilson Daniel MacArthur Christian R Marshall Peter N Ray James J Dowling

Ann Clin Transl Neurol 2016 01 8;3(1):55-60. Epub 2015 Dec 8.

Division of Neurology Hospital for Sick Children Toronto Ontario Canada M5G A04; Program of Genetics and Genome Biology Hospital for Sick Children Toronto Ontario Canada M5G A04; Department of Paediatrics University of Toronto Toronto Ontario Canada M5G AO4; Department of Molecular Genetics University of Toronto Toronto Ontario Canada M5G AO4.

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http://dx.doi.org/10.1002/acn3.267DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4704476PMC
January 2016

Layered genetic control of DNA methylation and gene expression: a locus of multiple sclerosis in healthy individuals.

Authors:
Jean Shin Celine Bourdon Manon Bernard Michael D Wilson Eva Reischl Melanie Waldenberger Barbara Ruggeri Gunter Schumann Sylvane Desrivieres Alexander Leemans Michal Abrahamowicz Gabriel Leonard Louis Richer Luigi Bouchard Daniel Gaudet Tomas Paus Zdenka Pausova

Hum Mol Genet 2015 Oct 28;24(20):5733-45. Epub 2015 Jul 28.

The Hospital for Sick Children, University of Toronto, Toronto, Canada, Department of Physiology, Department of Nutritional Sciences,

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http://dx.doi.org/10.1093/hmg/ddv294DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4581603PMC
October 2015

Evaluation of human and mosquito based diagnostic tools for defining endpoints for elimination of Anopheles transmitted lymphatic filariasis in Ghana.

Authors:
Irene Offei Owusu Dziedzom K de Souza Francis Anto Michael D Wilson Daniel A Boakye Moses J Bockarie John O Gyapong

Trans R Soc Trop Med Hyg 2015 Oct;109(10):628-35

School of Public Health, University of Ghana, Legon, Accra, Ghana

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October 2015

Epigenetics: a new player in the regulation of mammalian puberty.

Authors:
Paulina A Rzeczkowska Huayan Hou Michael D Wilson Mark R Palmert

Neuroendocrinology 2014 4;99(3-4):139-55. Epub 2014 Apr 4.

Division of Endocrinology, Hospital for Sick Children, Toronto, Ont., Canada.

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June 2015

Potential effects of warmer worms and vectors on onchocerciasis transmission in West Africa.

Authors:
Robert A Cheke Maria-Gloria Basáñez Malorie Perry Michael T White Rolf Garms Emmanuel Obuobie Poppy H L Lamberton Stephen Young Mike Y Osei-Atweneboana Joseph Intsiful Mingwang Shen Daniel A Boakye Michael D Wilson

Philos Trans R Soc Lond B Biol Sci 2015 Apr;370(1665)

Noguchi Memorial Institute for Medical Research, University of Ghana, PO Box LG 581, Legon, Accra, Ghana.

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http://dx.doi.org/10.1098/rstb.2013.0559DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4342963PMC
April 2015

Onchocerciasis transmission in Ghana: persistence under different control strategies and the role of the simuliid vectors.

Authors:
Poppy H L Lamberton Robert A Cheke Peter Winskill Iñaki Tirados Martin Walker Mike Y Osei-Atweneboana Nana-Kwadwo Biritwum Anthony Tetteh-Kumah Daniel A Boakye Michael D Wilson Rory J Post María-Gloria Basañez

PLoS Negl Trop Dis 2015 Apr 21;9(4):e0003688. Epub 2015 Apr 21.

London Centre for Neglected Tropical Disease Research, Department of Infectious Disease Epidemiology, Imperial College London, London, United Kingdom.

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http://dx.doi.org/10.1371/journal.pntd.0003688DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4405193PMC
April 2015

MACE: model based analysis of ChIP-exo.

Authors:
Liguo Wang Junsheng Chen Chen Wang Liis Uusküla-Reimand Kaifu Chen Alejandra Medina-Rivera Edwin J Young Michael T Zimmermann Huihuang Yan Zhifu Sun Yuji Zhang Stephen T Wu Haojie Huang Michael D Wilson Jean-Pierre A Kocher Wei Li

Nucleic Acids Res 2014 Nov 23;42(20):e156. Epub 2014 Sep 23.

Division of Biostatistics, Dan L. Duncan Cancer Center and Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX 77030, USA

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http://dx.doi.org/10.1093/nar/gku846DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4227761PMC
November 2014

Onchocerciasis transmission in Ghana: biting and parous rates of host-seeking sibling species of the Simulium damnosum complex.

Authors:
Poppy H L Lamberton Robert A Cheke Martin Walker Peter Winskill Mike Y Osei-Atweneboana Iñaki Tirados Anthony Tetteh-Kumah Daniel A Boakye Michael D Wilson Rory J Post María-Gloria Basáñez

Parasit Vectors 2014 Nov 21;7:511. Epub 2014 Nov 21.

London Centre for Neglected Tropical Disease Research, Department of Infectious Disease Epidemiology, School of Public Health, Imperial College London, St Mary's Campus, London, W2 1PG, UK.

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http://dx.doi.org/10.1186/s13071-014-0511-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4247625PMC
November 2014

Multi-species, multi-transcription factor binding highlights conserved control of tissue-specific biological pathways.

Authors:
Benoit Ballester Alejandra Medina-Rivera Dominic Schmidt Mar Gonzàlez-Porta Matthew Carlucci Xiaoting Chen Kyle Chessman Andre J Faure Alister P W Funnell Angela Goncalves Claudia Kutter Margus Lukk Suraj Menon William M McLaren Klara Stefflova Stephen Watt Matthew T Weirauch Merlin Crossley John C Marioni Duncan T Odom Paul Flicek Michael D Wilson

Elife 2014 Oct 3;3:e02626. Epub 2014 Oct 3.

Genetics and Genome Biology Program, SickKids Research Institute, Toronto, Canada.

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http://dx.doi.org/10.7554/eLife.02626DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4359374PMC
October 2014

First detection of Leishmania tropica DNA and Trypanosoma species in Sergentomyia sand flies (Diptera: Psychodidae) from an outbreak area of cutaneous leishmaniasis in Ghana.

Authors:
Chukwunonso O Nzelu Hirotomo Kato Naiki Puplampu Kwame Desewu Shirley Odoom Michael D Wilson Tatsuya Sakurai Ken Katakura Daniel A Boakye

PLoS Negl Trop Dis 2014 Feb 6;8(2):e2630. Epub 2014 Feb 6.

Department of Parasitology, Noguchi Memorial Institute for Medical Research, University of Ghana, Legon-Accra, Ghana.

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http://dx.doi.org/10.1371/journal.pntd.0002630DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3916256PMC
February 2014

Basophil depletion downregulates Schistosoma mansoni egg-induced granuloma formation.

Authors:
William K Anyan Takenori Seki Takashi Kumagai Kazushige Obata-Ninomiya Rieko Furushima-Shimogawara Bethel Kwansa-Bentum Nobuaki Akao Kwabena M Bosompem Daniel A Boakye Michael D Wilson Hajime Karasuyama Nobuo Ohta

Parasitol Int 2013 Dec 12;62(6):508-13. Epub 2013 Jul 12.

Department of Environmental Parasitology, Tokyo Medical and Dental University, Tokyo 113-8519, Japan; Department of Parasitology, Noguchi Memorial Institute for Medical Research, University of Ghana, Legon, Ghana.

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http://dx.doi.org/10.1016/j.parint.2013.07.003DOI Listing
December 2013

Cooperativity and rapid evolution of cobound transcription factors in closely related mammals.

Authors:
Klara Stefflova David Thybert Michael D Wilson Ian Streeter Jelena Aleksic Panagiota Karagianni Alvis Brazma David J Adams Iannis Talianidis John C Marioni Paul Flicek Duncan T Odom

Cell 2013 Aug;154(3):530-40

Cancer Research UK Cambridge Institute, Li Ka Shing Centre, University of Cambridge, Cambridge CB2 0RE, UK.

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http://dx.doi.org/10.1016/j.cell.2013.07.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3732390PMC
August 2013

Stability and change in the distribution of cytospecies of the Simulium damnosum complex (Diptera: Simuliidae) in southern Ghana from 1971 to 2011.

Authors:
Rory J Post Robert A Cheke Daniel A Boakye Michael D Wilson Mike Y Osei-Atweneboana Anthony Tetteh-Kumah Poppy Hl Lamberton J Lee Crainey Laurent Yaméogo María-Gloria Basáñez

Parasit Vectors 2013 Jul 13;6:205. Epub 2013 Jul 13.

School of Natural Sciences and Psychology, Liverpool John Moores University, Liverpool, UK.

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http://dx.doi.org/10.1186/1756-3305-6-205DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3727979PMC
July 2013

A CpG mutational hotspot in a ONECUT binding site accounts for the prevalent variant of hemophilia B Leyden.

Authors:
Alister P W Funnell Michael D Wilson Benoit Ballester Ka Sin Mak Jon Burdach Natisha Magan Richard C M Pearson Frederic P Lemaigre Kathryn M Stowell Duncan T Odom Paul Flicek Merlin Crossley

Am J Hum Genet 2013 Mar;92(3):460-7

School of Biotechnology and Biomolecular Sciences, University of New South Wales, Kensington, NSW 2052, Australia.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3591849PMC
March 2013

Rapid turnover of long noncoding RNAs and the evolution of gene expression.

Authors:
Claudia Kutter Stephen Watt Klara Stefflova Michael D Wilson Angela Goncalves Chris P Ponting Duncan T Odom Ana C Marques

PLoS Genet 2012 26;8(7):e1002841. Epub 2012 Jul 26.

Cancer Research UK, Cambridge Research Institute, Li Ka Shing Centre, Cambridge, United Kingdom.

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http://dx.doi.org/10.1371/journal.pgen.1002841DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3406015PMC
January 2013

Latent regulatory potential of human-specific repetitive elements.

Authors:
Michelle C Ward Michael D Wilson Nuno L Barbosa-Morais Dominic Schmidt Rory Stark Qun Pan Petra C Schwalie Suraj Menon Margus Lukk Stephen Watt David Thybert Claudia Kutter Kristina Kirschner Paul Flicek Benjamin J Blencowe Duncan T Odom

Mol Cell 2013 Jan 13;49(2):262-72. Epub 2012 Dec 13.

University of Cambridge, Cancer Research UK-Cambridge Institute, Cambridge CB2 0RE, UK.

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http://dx.doi.org/10.1016/j.molcel.2012.11.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3560060PMC
January 2013

The evolutionary landscape of alternative splicing in vertebrate species.

Authors:
Nuno L Barbosa-Morais Manuel Irimia Qun Pan Hui Y Xiong Serge Gueroussov Leo J Lee Valentina Slobodeniuc Claudia Kutter Stephen Watt Recep Colak TaeHyung Kim Christine M Misquitta-Ali Michael D Wilson Philip M Kim Duncan T Odom Brendan J Frey Benjamin J Blencowe

Science 2012 Dec;338(6114):1587-93

Banting and Best Department of Medical Research, Donnelly Centre, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1126/science.1230612DOI Listing
December 2012

Cohesin regulates tissue-specific expression by stabilizing highly occupied cis-regulatory modules.

Authors:
Andre J Faure Dominic Schmidt Stephen Watt Petra C Schwalie Michael D Wilson Huiling Xu Robert G Ramsay Duncan T Odom Paul Flicek

Genome Res 2012 Nov 10;22(11):2163-75. Epub 2012 Jul 10.

European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, United Kingdom.

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http://dx.doi.org/10.1101/gr.136507.111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3483546PMC
November 2012

Diversity and transmission competence in lymphatic filariasis vectors in West Africa, and the implications for accelerated elimination of Anopheles-transmitted filariasis.

Authors:
Dziedzom K de Souza Benjamin Koudou Louise A Kelly-Hope Michael D Wilson Moses J Bockarie Daniel A Boakye

Parasit Vectors 2012 Nov 14;5:259. Epub 2012 Nov 14.

Parasitology Department, Noguchi Memorial Institute for Medical Research, University of Ghana, Legon-Accra, Ghana.

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http://dx.doi.org/10.1186/1756-3305-5-259DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3533928PMC
November 2012

Haplotype analyses of haemoglobin C and haemoglobin S and the dynamics of the evolutionary response to malaria in Kassena-Nankana District of Ghana.

Authors:
Anita Ghansah Kirk A Rockett Taane G Clark Michael D Wilson Kwadwo A Koram Abraham R Oduro Lucas Amenga-Etego Thomas Anyorigiya Abraham Hodgson Paul Milligan William O Rogers Dominic P Kwiatkowski

PLoS One 2012 10;7(4):e34565. Epub 2012 Apr 10.

Noguchi Memorial Institute for Medical Research, University of Ghana, Accra, Ghana.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3323552PMC
October 2012

Replication-timing boundaries facilitate cell-type and species-specific regulation of a rearranged human chromosome in mouse.

Authors:
Benjamin D Pope Tamir Chandra Quinton Buckley Matthew Hoare Tyrone Ryba Frances K Wiseman Anna Kuta Michael D Wilson Duncan T Odom David M Gilbert

Hum Mol Genet 2012 Oct 26;21(19):4162-70. Epub 2012 Jun 26.

Department of Biological Science, Florida State University, Tallahassee, FL 32306, USA.

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http://dx.doi.org/10.1093/hmg/dds232DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3441118PMC
October 2012

Characterization of malaria transmission by vector populations for improved interventions during the dry season in the Kpone-on-Sea area of coastal Ghana.

Authors:
David P Tchouassi Isabella A Quakyi Ebenezer A Addison Kwabena M Bosompem Michael D Wilson Maxwell A Appawu Charles A Brown Daniel A Boakye

Parasit Vectors 2012 Sep 26;5:212. Epub 2012 Sep 26.

School of Public Health, University of Ghana, Legon, Ghana.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3495633PMC
September 2012

Independence of repressive histone marks and chromatin compaction during senescent heterochromatic layer formation.

Authors:
Tamir Chandra Kristina Kirschner Jean-Yves Thuret Benjamin D Pope Tyrone Ryba Scott Newman Kashif Ahmed Shamith A Samarajiwa Rafik Salama Thomas Carroll Rory Stark Rekin's Janky Masako Narita Lixiang Xue Agustin Chicas Sabrina Nũnez Ralf Janknecht Yoko Hayashi-Takanaka Michael D Wilson Aileen Marshall Duncan T Odom M Madan Babu David P Bazett-Jones Simon Tavaré Paul A W Edwards Scott W Lowe Hiroshi Kimura David M Gilbert Masashi Narita

Mol Cell 2012 Jul 12;47(2):203-14. Epub 2012 Jul 12.

Cancer Research UK Cambridge Research Institute, Li Ka Shing Centre, Robinson Way, Cambridge CB2 0RE, UK.

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http://dx.doi.org/10.1016/j.molcel.2012.06.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3701408PMC
July 2012

A feedback loop between the liver-enriched transcription factor network and miR-122 controls hepatocyte differentiation.

Authors:
Ilaria Laudadio Isabelle Manfroid Younes Achouri Dominic Schmidt Michael D Wilson Sabine Cordi Lieven Thorrez Laurent Knoops Patrick Jacquemin Frans Schuit Christophe E Pierreux Duncan T Odom Bernard Peers Frédéric P Lemaigre

Gastroenterology 2012 Jan 12;142(1):119-29. Epub 2011 Sep 12.

De Duve Institute, Université Catholique de Louvain, Brussels, Belgium.

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January 2012

Waves of retrotransposon expansion remodel genome organization and CTCF binding in multiple mammalian lineages.

Authors:
Dominic Schmidt Petra C Schwalie Michael D Wilson Benoit Ballester Angela Gonçalves Claudia Kutter Gordon D Brown Aileen Marshall Paul Flicek Duncan T Odom

Cell 2012 Jan 12;148(1-2):335-48. Epub 2012 Jan 12.

Cancer Research UK, Cambridge Research Institute, Li Ka Shing Centre, Robinson Way, Cambridge CB2 0RE, UK.

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http://dx.doi.org/10.1016/j.cell.2011.11.058DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3368268PMC
January 2012

Administrative practices of health professionals and use of artesunate-amodiaquine by community members for treating uncomplicated malaria in southern Ghana: implications for artemisinin-based combination therapy deployment.

Authors:
Bethel Kwansa-Bentum Irene Ayi Takashi Suzuki Joseph Otchere Takashi Kumagai William K Anyan Hiroko Asahi Nobuaki Akao Michael D Wilson Daniel A Boakye Nobuo Ohta

Trop Med Int Health 2011 Oct 10;16(10):1215-24. Epub 2011 Jul 10.

Section of Environmental Parasitology, Tokyo Medical and Dental University, Tokyo, Japan.

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http://dx.doi.org/10.1111/j.1365-3156.2011.02833.xDOI Listing
October 2011

Pol III binding in six mammals shows conservation among amino acid isotypes despite divergence among tRNA genes.

Authors:
Claudia Kutter Gordon D Brown Angela Gonçalves Michael D Wilson Stephen Watt Alvis Brazma Robert J White Duncan T Odom

Nat Genet 2011 Aug 28;43(10):948-55. Epub 2011 Aug 28.

Cancer Research UK, Cambridge Research Institute, Li Ka Shing Centre, Cambridge, UK.

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http://dx.doi.org/10.1038/ng.906DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3184141PMC
August 2011

Plasmodium falciparum isolates from southern Ghana exhibit polymorphisms in the SERCA-type PfATPase6 though sensitive to artesunate in vitro.

Authors:
Bethel Kwansa-Bentum Irene Ayi Takashi Suzuki Joseph Otchere Takashi Kumagai William K Anyan Joseph H N Osei Hiroko Asahi Michael F Ofori Nobuaki Akao Michael D Wilson Daniel A Boakye Nobuo Ohta

Malar J 2011 Jul 11;10:187. Epub 2011 Jul 11.

Section of Environmental Parasitology, Department of International Health Development, Tokyo Medical and Dental University, 5-45 Yushima 1-chome, Bunkyo-ku, Tokyo, Japan.

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http://dx.doi.org/10.1186/1475-2875-10-187DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3146903PMC
July 2011

High body mass index is not associated with atopy in schoolchildren living in rural and urban areas of Ghana.

Authors:
Irene A Larbi Kerstin Klipstein-Grobusch Abena S Amoah Benedicta B Obeng Michael D Wilson Maria Yazdanbakhsh Daniel A Boakye

BMC Public Health 2011 Jun 14;11:469. Epub 2011 Jun 14.

Division of Epidemiology & Biostatistics, School of Public Health, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.

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http://dx.doi.org/10.1186/1471-2458-11-469DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3141453PMC
June 2011

Adaptive divergence between incipient species of Anopheles gambiae increases resistance to Plasmodium.

Authors:
Bradley J White Mara K N Lawniczak Changde Cheng Mamadou B Coulibaly Michael D Wilson N'Fale Sagnon Carlo Costantini Frederic Simard George K Christophides Nora J Besansky

Proc Natl Acad Sci U S A 2011 Jan 20;108(1):244-9. Epub 2010 Dec 20.

Eck Institute for Global Health, Department of Biological Sciences, University of Notre Dame, Notre Dame, IN 46556, USA.

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http://dx.doi.org/10.1073/pnas.1013648108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3017163PMC
January 2011

Selective sweeps and genetic lineages of Plasmodium falciparum drug -resistant alleles in Ghana.

Authors:
Md Tauqeer Alam Dziedzom K de Souza Sumiti Vinayak Sean M Griffing Amanda C Poe Nancy O Duah Anita Ghansah Kwame Asamoa Laurence Slutsker Michael D Wilson John W Barnwell Venkatachalam Udhayakumar Kwadwo A Koram

J Infect Dis 2011 Jan;203(2):220-7

Malaria Branch, Division of Parasitic Diseases and Malaria, Center for Global Health, Centers for Disease Control and Prevention, Atlanta, GA 30329, USA.

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http://dx.doi.org/10.1093/infdis/jiq038DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3071065PMC
January 2011

Studies of Anopheles gambiae s.l (Diptera: Culicidae) exhibiting different vectorial capacities in lymphatic filariasis transmission in the Gomoa district, Ghana.

Authors:
Hilaria Amuzu Michael D Wilson Daniel A Boakye

Parasit Vectors 2010 Sep 14;3:85. Epub 2010 Sep 14.

Department of Parasitology, Noguchi Memorial Institute for Medical Research, University of Ghana, P,O, Box LG 581, Legon, Accra, Ghana.

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http://dx.doi.org/10.1186/1756-3305-3-85DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2949826PMC
September 2010

Zonadhesin is essential for species specificity of sperm adhesion to the egg zona pellucida.

Authors:
Steve Tardif Michael D Wilson Rebecca Wagner Peter Hunt Marina Gertsenstein Andras Nagy Corrinne Lobe Ben F Koop Daniel M Hardy

J Biol Chem 2010 Aug 7;285(32):24863-70. Epub 2010 Jun 7.

Department of Cell Biology and Biochemistry, Texas Tech University Health Sciences Center, Lubbock, Texas 79430-6540, USA.

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http://www.jbc.org/cgi/doi/10.1074/jbc.M110.123125
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2915722PMC
August 2010

Cohort trial reveals community impact of insecticide-treated nets on malariometric indices in urban Ghana.

Authors:
Eveline Klinkenberg Kwabena A Onwona-Agyeman P J McCall Michael D Wilson Imelda Bates Francine H Verhoeff Guy Barnish Martin J Donnelly

Trans R Soc Trop Med Hyg 2010 Jul 24;104(7):496-503. Epub 2010 Apr 24.

Liverpool School of Tropical Medicine, Pembroke Place, Liverpool L3 5QA, UK.

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July 2010

Five-vertebrate ChIP-seq reveals the evolutionary dynamics of transcription factor binding.

Authors:
Dominic Schmidt Michael D Wilson Benoit Ballester Petra C Schwalie Gordon D Brown Aileen Marshall Claudia Kutter Stephen Watt Celia P Martinez-Jimenez Sarah Mackay Iannis Talianidis Paul Flicek Duncan T Odom

Science 2010 May 8;328(5981):1036-40. Epub 2010 Apr 8.

Cancer Research UK, Cambridge Research Institute, Li Ka Shing Centre, Robinson Way, Cambridge CB2 0RE, UK.

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http://dx.doi.org/10.1126/science.1186176DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3008766PMC
May 2010

Disruption of the single copy gonadotropin-releasing hormone receptor in mice by gene trap: severe reduction of reproductive organs and functions in developing and adult mice.

Authors:
Sheng Wu Michael D Wilson Ellen R Busby Emma R Isaac Nancy M Sherwood

Endocrinology 2010 Mar 12;151(3):1142-52. Epub 2010 Jan 12.

Department of Biology, University of Victoria, 3800 Finnerty Road, Victoria, British Columbia, Canada.

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http://dx.doi.org/10.1210/en.2009-0598DOI Listing
March 2010

Evolution of transcriptional control in mammals.

Authors:
Michael D Wilson Duncan T Odom

Curr Opin Genet Dev 2009 Dec 11;19(6):579-85. Epub 2009 Nov 11.

Cancer Research UK, Cambridge Research Institute, Li Ka Shing Centre, Robinson Way, Cambridge CB2 0RE, UK.

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http://dx.doi.org/10.1016/j.gde.2009.10.003DOI Listing
December 2009

ChIP-seq: using high-throughput sequencing to discover protein-DNA interactions.

Authors:
Dominic Schmidt Michael D Wilson Christiana Spyrou Gordon D Brown James Hadfield Duncan T Odom

Methods 2009 Jul 9;48(3):240-8. Epub 2009 Mar 9.

Department of Oncology, Hutchison/MRC Research Centre, Hills Road, Cambridge CB20XZ, UK.

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http://dx.doi.org/10.1016/j.ymeth.2009.03.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4052679PMC
July 2009

Cardiocladius oliffi (Diptera: Chironomidae) as a potential biological control agent against Simulium squamosum (Diptera: Simuliidae).

Authors:
Daniel A Boakye Eric Fokam Anita Ghansah Josef Amakye Michael D Wilson Charles A Brown

Parasit Vectors 2009 Apr 24;2(1):20. Epub 2009 Apr 24.

Noguchi Memorial Institute for Medical Research, Box LG581, Legon, Accra, Ghana.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2683824PMC
April 2009

Genome-scale validation of deep-sequencing libraries.

Authors:
Dominic Schmidt Rory Stark Michael D Wilson Gordon D Brown Duncan T Odom

PLoS One 2008 12;3(11):e3713. Epub 2008 Nov 12.

Cancer Research UK, Cambridge Research Institute, Li Ka Shing Centre, Cambridge, UK.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2577887PMC
December 2008

Species-specific transcription in mice carrying human chromosome 21.

Authors:
Michael D Wilson Nuno L Barbosa-Morais Dominic Schmidt Caitlin M Conboy Lesley Vanes Victor L J Tybulewicz Elizabeth M C Fisher Simon Tavaré Duncan T Odom

Science 2008 Oct 11;322(5900):434-8. Epub 2008 Sep 11.

Cancer Research UK, Cambridge Research Institute, Li Ka Shing Centre, Robinson Way, Cambridge CB2 0RE, UK.

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http://dx.doi.org/10.1126/science.1160930DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3717767PMC
October 2008

Impact of urban agriculture on malaria vectors in Accra, Ghana.

Authors:
Eveline Klinkenberg Pj McCall Michael D Wilson Felix P Amerasinghe Martin J Donnelly

Malar J 2008 Aug 4;7:151. Epub 2008 Aug 4.

International Water Management Institute (IWMI), West Africa Office, Ghana.

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http://dx.doi.org/10.1186/1475-2875-7-151DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2515328PMC
August 2008

Lower expression of TLR2 and SOCS-3 is associated with Schistosoma haematobium infection and with lower risk for allergic reactivity in children living in a rural area in Ghana.

Authors:
Franca C Hartgers Benedicta B Obeng Yvonne C M Kruize Marjolijn Duijvestein Anna de Breij Abena Amoah Irene A Larbi Ronald van Ree Michael D Wilson Laura C Rodrigues Daniel A Boakye Maria Yazdanbakhsh

PLoS Negl Trop Dis 2008 Apr 16;2(4):e227. Epub 2008 Apr 16.

Department of Parasitology, Leiden University Medical Centre, Leiden, The Netherlands.

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http://dx.doi.org/10.1371/journal.pntd.0000227DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2291570PMC
April 2008

ARS2 is a conserved eukaryotic gene essential for early mammalian development.

Authors:
Michael D Wilson Diana Wang Rebecca Wagner Hilde Breyssens Marina Gertsenstein Corrinne Lobe Xin Lu Andras Nagy Robert D Burke Ben F Koop Perry L Howard

Mol Cell Biol 2008 Mar 17;28(5):1503-14. Epub 2007 Dec 17.

Centre for Biomedical Research, University of Victoria, P.O. Box 3020 Station CSC, Victoria, BC, Canada.

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http://dx.doi.org/10.1128/MCB.01565-07DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2258792PMC
March 2008

Estimating dispersal and survival of Anopheles gambiae and Anopheles funestus along the Kenyan coast by using mark-release-recapture methods.

Authors:
Janet T Midega Charles M Mbogo Henry Mwnambi Michael D Wilson Gordon Ojwang Joseph M Mwangangi Joseph G Nzovu John I Githure Guiyun Yan John C Beier

J Med Entomol 2007 Nov;44(6):923-9

Department of Entomology, Kenya Medical Research Institute, Centre for Geographic Medicine Research-Coast, P.O. Box 428, Kilifi, Kenya.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2705338PMC
http://dx.doi.org/10.1603/0022-2585(2007)44[923:edasoa]2.0.co;2DOI Listing
November 2007

Monitoring lymphatic filariasis interventions: Adult mosquito sampling, and improved PCR - based pool screening method for Wuchereria bancrofti infection in Anopheles mosquitoes.

Authors:
Daniel A Boakye Helena A Baidoo Evans Glah Charles Brown Maxwell Appawu Michael D Wilson

Filaria J 2007 Nov 29;6:13. Epub 2007 Nov 29.

Department of Parasitology, Noguchi Memorial Institute for Medical Research, University of Ghana, P,O, Box LG 581, Legon, Accra, Ghana.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2235849PMC
November 2007

Cell cycle genes are the evolutionarily conserved targets of the E2F4 transcription factor.

Authors:
Caitlin M Conboy Christiana Spyrou Natalie P Thorne Elizabeth J Wade Nuno L Barbosa-Morais Michael D Wilson Arindam Bhattacharjee Richard A Young Simon Tavaré Jacqueline A Lees Duncan T Odom

PLoS One 2007 Oct 24;2(10):e1061. Epub 2007 Oct 24.

Cancer Research UK-Cambridge Research Institute, Li Ka Shing Centre, Cambridge, United Kingdom.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2020443PMC
October 2007

Ecological zones rather than molecular forms predict genetic differentiation in the malaria vector Anopheles gambiae s.s. in Ghana.

Authors:
Alexander E Yawson David Weetman Michael D Wilson Martin J Donnelly

Genetics 2007 Feb 16;175(2):751-61. Epub 2006 Nov 16.

Vector Group, Liverpool School of Tropical Medicine, Liverpool L3 5QA, United Kingdom.

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http://dx.doi.org/10.1534/genetics.106.065888DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1800615PMC
February 2007

Mutations in Plasmodium falciparum chloroquine resistance transporter and multidrug resistance genes, and treatment outcomes in Ghanaian children with uncomplicated malaria.

Authors:
Nancy O Duah Michael D Wilson Anita Ghansah Ben Abuaku Dominic Edoh Neils B Quashie Kwadwo A Koram

J Trop Pediatr 2007 Feb 10;53(1):27-31. Epub 2006 Dec 10.

Noguchi Memorial Institute for Medical Research, University of Ghana, P.O. Box LG581, Legon, Ghana.

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http://dx.doi.org/10.1093/tropej/fml076DOI Listing
February 2007

Comparative analysis of the paired immunoglobulin-like receptor (PILR) locus in six mammalian genomes: duplication, conversion, and the birth of new genes.

Authors:
Michael D Wilson Joseph Cheung Duane W Martindale Stephen W Scherer Ben F Koop

Physiol Genomics 2006 Nov 22;27(3):201-18. Epub 2006 Aug 22.

Centre for Biomedical Research, Department of Biology, University of Victoria, British Columbia, Canada.

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http://dx.doi.org/10.1152/physiolgenomics.00284.2005DOI Listing
November 2006

A combined school- and community-based campaign targeting all school-age children of Burkina Faso against schistosomiasis and soil-transmitted helminthiasis: performance, financial costs and implications for sustainability.

Authors:
Albis-Francesco Gabrielli Seydou Touré Bertrand Sellin Elisabeth Sellin Césaire Ky Hamado Ouedraogo Malachie Yaogho Michael D Wilson Howard Thompson Souleymane Sanou Alan Fenwick

Acta Trop 2006 Oct 25;99(2-3):234-42. Epub 2006 Sep 25.

Schistosomiasis Control Initiative, Imperial College London, St Mary's Campus, Norfolk Place, London W2 1PG, UK.

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http://dx.doi.org/10.1016/j.actatropica.2006.08.008DOI Listing
October 2006

Short report: ITS-1 DNA sequence confirmation of Leishmania major as a cause of cutaneous leishmaniasis from an outbreak focus in the Ho district, southeastern Ghana.

Authors:
David J Fryauff Hanafi A Hanafi John D Klena David F Hoel Maxwell Appawu William Rogers Naiki Puplampu Shirley Odoom Margaret Kweku Kwadwo Koram Michael D Wilson Gregory Raczniak Daniel Boakye

Am J Trop Med Hyg 2006 Sep;75(3):502-4

Research Science Directorate, Enteric Disease Research Program, Vector Biology Research Program, Ghana Detachment, US Naval Medical Research Unit 3, Cairo, Egypt.

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September 2006

Urban malaria and anaemia in children: a cross-sectional survey in two cities of Ghana.

Authors:
Eveline Klinkenberg P J McCall Michael D Wilson Alex O Akoto Felix P Amerasinghe Imelda Bates Francine H Verhoeff Guy Barnish Martin J Donnelly

Trop Med Int Health 2006 May;11(5):578-88

International Water Management Institute, Accra, Ghana.

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http://doi.wiley.com/10.1111/j.1365-3156.2006.01609.x
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May 2006

Expression and genomic organization of zonadhesin-like genes in three species of fish give insight into the evolutionary history of a mosaic protein.

Authors:
Peter N D Hunt Michael D Wilson Kristian R von Schalburg William S Davidson Ben F Koop

BMC Genomics 2005 Nov 22;6:165. Epub 2005 Nov 22.

Centre for Biomedical Research, University of Victoria, Victoria, British Columbia V8W 3N5, Canada.

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http://dx.doi.org/10.1186/1471-2164-6-165DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1325057PMC
November 2005

Malaria and irrigated crops, Accra, Ghana.

Authors:
Eveline Klinkenberg P J McCall Ian M Hastings Michael D Wilson Felix P Amerasinghe Martin J Donnelly

Emerg Infect Dis 2005 Aug;11(8):1290-3

Liverpool School of Tropical Medicine, Liverpool, United Kingdom.

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http://dx.doi.org/10.3201/eid1108.041095DOI Listing
August 2005