Publications by authors named "Michael D Taylor"

100Publications

Outcomes of BRAF V600E Pediatric Gliomas Treated With Targeted BRAF Inhibition.

JCO Precis Oncol 2020 20;4. Epub 2020 May 20.

Department of Hematology and Oncology, Hospital for Sick Children, Toronto, ON, Canada.

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http://dx.doi.org/10.1200/PO.19.00298DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7446502PMC
May 2020

Neurotrophin Signaling in Medulloblastoma.

Cancers (Basel) 2020 Sep 7;12(9). Epub 2020 Sep 7.

Cancer and Neurobiology Laboratory, Experimental Research Center, Clinical Hospital (CPE-HCPA), Federal University of Rio Grande do Sul, Porto Alegre 90035-003, RS, Brazil.

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http://dx.doi.org/10.3390/cancers12092542DOI Listing
September 2020

Radiation-induced intracranial aneurysm presenting with acute hemorrhage in a child treated for medulloblastoma.

Childs Nerv Syst 2020 Aug 9. Epub 2020 Aug 9.

Department of Diagnostic Imaging, Division of Neuroradiology, The Hospital for Sick Children, University of Toronto, 555 University Ave, Toronto, ON, M5G 1X8, Canada.

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http://dx.doi.org/10.1007/s00381-020-04853-7DOI Listing
August 2020

Breath-hold and free-breathing quantitative assessment of biventricular volume and function using compressed SENSE: a clinical validation in children and young adults.

J Cardiovasc Magn Reson 2020 Jul 27;22(1):54. Epub 2020 Jul 27.

Department of Radiology, Cincinnati Children's Hospital Medical Center, 3333 Burnet Ave, Cincinnati, OH, 45229, USA.

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http://dx.doi.org/10.1186/s12968-020-00642-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7384228PMC
July 2020

Cardiovascular magnetic resonance imaging derived septal curvature in neonates with bronchopulmonary dysplasia associated pulmonary hypertension.

J Cardiovasc Magn Reson 2020 Jul 23;22(1):50. Epub 2020 Jul 23.

Center for Pulmonary Imaging Research, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.

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http://dx.doi.org/10.1186/s12968-020-00643-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7376717PMC
July 2020

Nailing a Fe-rocious form of cancer.

Science 2020 07;369(6501):250-251

Department of Neurosurgery, Hospital for Sick Children, Toronto, Canada.

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http://dx.doi.org/10.1126/science.abb7041DOI Listing
July 2020

DDX3X Suppresses the Susceptibility of Hindbrain Lineages to Medulloblastoma.

Dev Cell 2020 Aug 17;54(4):455-470.e5. Epub 2020 Jun 17.

CRUK Cambridge Institute, University of Cambridge, Li Ka Shing Centre, Robinson Way, Cambridge CB2 0RE, UK; Department of Oncology, University of Cambridge, Li Ka Shing Centre, Robinson Way, Cambridge CB2 0RE, UK. Electronic address:

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http://dx.doi.org/10.1016/j.devcel.2020.05.027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7483908PMC
August 2020

Response to "Externally Controlled Trials: Are We There Yet?"

Clin Pharmacol Ther 2020 Jun 15. Epub 2020 Jun 15.

Research Triangle International, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1002/cpt.1880DOI Listing
June 2020

Metabolic Regulation of the Epigenome Drives Lethal Infantile Ependymoma.

Cell 2020 Jun 22;181(6):1329-1345.e24. Epub 2020 May 22.

The Arthur and Sonia Labatt Brain Tumor Research Center, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada; Developmental & Stem Cell Biology Program, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON M5G 1L7, Canada; Department of Medical Biophysics, University of Toronto, Toronto, ON M5G 1L7, Canada; Division of Neurosurgery, The Hospital for Sick Children, Toronto, ON M5G 1L7, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2020.04.047DOI Listing
June 2020

Expression of GNAS, TP53, and PTEN Improves the Patient Prognostication in Sonic Hedgehog (SHH) Medulloblastoma Subgroup.

J Mol Diagn 2020 Jul 4;22(7):957-966. Epub 2020 May 4.

Molecular Oncology Research Center, Barretos Cancer Hospital, São Paulo, Brazil; Molecular Diagnostic Laboratory, Barretos Cancer Hospital, São Paulo, Brazil; Life and Health Sciences Research Institute, School of Medicine, University of Minho, Braga, Portugal; Life and Health Sciences Research Institute/3B's-PT Government Associate Laboratory, Braga/Guimarães, Portugal. Electronic address:

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http://dx.doi.org/10.1016/j.jmoldx.2020.04.207DOI Listing
July 2020

Reply to S.A. Milgrom et al.

J Clin Oncol 2020 Jul 6;38(19):2212-2213. Epub 2020 May 6.

Lisa S. Kahalley, PhD, Department of Pediatrics, Section of Psychology, Baylor College of Medicine, Houston, TX; Rachel Peterson, PhD, Department of Psychology, The Hospital for Sick Children, Toronto, Ontario, Canada; M. Douglas Ris, PhD, Department of Pediatrics, Section of Psychology, Baylor College of Medicine, Houston, TX; Laura Janzen, PhD, Department of Psychology, The Hospital for Sick Children, Toronto, Ontario, Canada; M. Fatih Okcu, MPH, MD, Department of Pediatrics, Section of Hematology Oncology, Baylor College of Medicine, Houston, TX; David R. Grosshans, MD, PhD, Division of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX; Vijay Ramaswamy, MD, PhD, Division of Haematology/Oncology, The Hospital for Sick Children, and Department of Paediatrics, The University of Toronto, Toronto, Ontario, Canada; Arnold C. Paulino, MD, Division of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX; David Hodgson, MPH, MD, Department of Radiation Oncology, Princess Margaret Cancer Centre, Toronto, Ontario, Canada; Anita Mahajan, MD, Department of Radiation Oncology, The Mayo Clinic, Rochester, MN; Derek S. Tsang, MSc, MD and Normand Laperriere, MD, Department of Radiation Oncology, Princess Margaret Cancer Centre, Toronto, Ontario, Canada; WilliamE. Whitehead, MPH, MD and Robert C.Dauser, MD, Department of Neurosurgery, Division of Pediatric Neurosurgery, Baylor College of Medicine, Houston, TX; Michael D. Taylor, MD, PhD, Division of Neurosurgery, The Hospital for Sick Children, and Department of Surgery, The University of Toronto, Toronto, Ontario, Canada; Eric Bouffet, MD, Division of Haematology/Oncology, The Hospital for Sick Children, and Department of Paediatrics, The University of Toronto, Toronto, Ontario, Canada; Murali Chintagumpala, MD, Department of Pediatrics, Section of Hematology Oncology, Baylor College of Medicine, Houston, TX; and Donald Mabbott, PhD, Program in Neurosciences and Mental Health, Research Institute, The Hospital for Sick Children, and Department of Psychology, The University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1200/JCO.20.00344DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7325365PMC
July 2020

Hemodynamics and tissue biomechanics of the thoracic aorta with a trileaflet aortic valve at different phases of valve opening.

Int J Numer Method Biomed Eng 2020 Jul 14;36(7):e3345. Epub 2020 May 14.

Heart Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.

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http://dx.doi.org/10.1002/cnm.3345DOI Listing
July 2020

Medulloblastoma Arises from the Persistence of a Rare and Transient Sox2 Granule Neuron Precursor.

Cell Rep 2020 Apr;31(2):107511

Developmental and Stem Cell Biology Program, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada; Arthur and Sonia Labatt Brain Tumor Research Centre, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada; Department of Molecular Genetics, University of Toronto, Toronto, ON M5S 1A8, Canada; Division of Neurosurgery, University of Toronto, Toronto, ON M5S 1A8, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2020.03.075DOI Listing
April 2020

Recombinant human insulin-like growth factor-1 therapy for 6 months improves growth but not motor function in boys with Duchenne muscular dystrophy.

Muscle Nerve 2020 05 16;61(5):623-631. Epub 2020 Mar 16.

Division of Endocrinology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.

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http://dx.doi.org/10.1002/mus.26846DOI Listing
May 2020

HDAC and MAPK/ERK Inhibitors Cooperate To Reduce Viability and Stemness in Medulloblastoma.

J Mol Neurosci 2020 Jun 13;70(6):981-992. Epub 2020 Feb 13.

Cancer and Neurobiology Laboratory, Experimental Research Center, Clinical Hospital (CPE-HCPA), Federal University of Rio Grande do Sul, Porto Alegre, RS, Brazil.

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http://dx.doi.org/10.1007/s12031-020-01505-yDOI Listing
June 2020

Immunohistochemical and nanoString-Based Subgrouping of Clinical Medulloblastoma Samples.

J Neuropathol Exp Neurol 2020 Apr;79(4):437-447

Division of Pathology, The Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1093/jnen/nlaa005DOI Listing
April 2020

Correction to: Postoperative isolated lower extremity supplementary motor area syndrome: case report and review of the literature.

Childs Nerv Syst 2020 Apr;36(4):877

Division of Neurosurgery, Department of Surgery, University of Toronto, Toronto, ON, Canada.

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http://dx.doi.org/10.1007/s00381-020-04504-xDOI Listing
April 2020

Introduction. Pediatric brain tumor.

Neurosurg Focus 2020 01;48(1):E1

5Department of Neurology, Sandler Neuroscience Center, University of California, San Francisco, California.

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http://dx.doi.org/10.3171/2019.10.FOCUS19799DOI Listing
January 2020

The molecular biology of medulloblastoma metastasis.

Brain Pathol 2020 05 15;30(3):691-702. Epub 2020 Jan 15.

Developmental and Stem Cell Biology Program, The Hospital for Sick Children, Toronto, ON, Canada.

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http://dx.doi.org/10.1111/bpa.12811DOI Listing
May 2020

Postoperative isolated lower extremity supplementary motor area syndrome: case report and review of the literature.

Childs Nerv Syst 2020 01 9;36(1):189-195. Epub 2019 Nov 9.

Division of Neurosurgery, Department of Surgery, University of Toronto, Toronto, ON, Canada.

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http://dx.doi.org/10.1007/s00381-019-04362-2DOI Listing
January 2020

Effects of Normal Variation in the Rotational Position of the Aortic Root on Hemodynamics and Tissue Biomechanics of the Thoracic Aorta.

Cardiovasc Eng Technol 2020 02 7;11(1):47-58. Epub 2019 Nov 7.

Heart Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 45229, USA.

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http://dx.doi.org/10.1007/s13239-019-00441-2DOI Listing
February 2020

Recurrent noncoding U1 snRNA mutations drive cryptic splicing in SHH medulloblastoma.

Nature 2019 10 9;574(7780):707-711. Epub 2019 Oct 9.

The Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1038/s41586-019-1650-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7141958PMC
October 2019

The U1 spliceosomal RNA is recurrently mutated in multiple cancers.

Nature 2019 10 9;574(7780):712-716. Epub 2019 Oct 9.

Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1038/s41586-019-1651-zDOI Listing
October 2019

Medulloblastoma in the age of molecular subgroups: a review.

J Neurosurg Pediatr 2019 10;24(4):353-363

1Division of Neurosurgery.

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http://dx.doi.org/10.3171/2019.5.PEDS18381DOI Listing
October 2019

Re-irradiation for children with recurrent medulloblastoma in Toronto, Canada: a 20-year experience.

J Neurooncol 2019 Oct 29;145(1):107-114. Epub 2019 Aug 29.

Radiation Medicine Program, Princess Margaret Cancer Centre, University Health Network, 610 University Avenue, Toronto, ON, M5G 2M9, Canada.

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http://dx.doi.org/10.1007/s11060-019-03272-2DOI Listing
October 2019

mDixon ECG-gated 3-dimensional cardiovascular magnetic resonance angiography in patients with congenital cardiovascular disease.

J Cardiovasc Magn Reson 2019 08 8;21(1):52. Epub 2019 Aug 8.

The Heart Institute, Department of Pediatrics, David's Medical Center, 919 East 32nd Street, Austin, TX, 78705, USA.

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http://dx.doi.org/10.1186/s12968-019-0554-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6686451PMC
August 2019

Conservative gadolinium administration to patients with Duchenne muscular dystrophy: decreasing exposure, cost, and time, without change in medical management.

Int J Cardiovasc Imaging 2019 Dec 18;35(12):2213-2219. Epub 2019 Jul 18.

Heart Institute, Cincinnati Children's Hospital Medical Center, 3333 Burnet Avenue, MLC 2003, Cincinnati, OH, 45229, USA.

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http://dx.doi.org/10.1007/s10554-019-01670-1DOI Listing
December 2019

Antitumor Activities and Cellular Changes Induced by TrkB Inhibition in Medulloblastoma.

Front Pharmacol 2019 26;10:698. Epub 2019 Jun 26.

Cancer and Neurobiology Laboratory, Experimental Research Center, Clinical Hospital (CPE-HCPA), Federal University of Rio Grande do Sul, Porto Alegre, Brazil.

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http://dx.doi.org/10.3389/fphar.2019.00698DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6606946PMC
June 2019

A C19MC-LIN28A-MYCN Oncogenic Circuit Driven by Hijacked Super-enhancers Is a Distinct Therapeutic Vulnerability in ETMRs: A Lethal Brain Tumor.

Cancer Cell 2019 07;36(1):51-67.e7

Arthur and Sonia Labatt Brain Tumor Research Centre, Division of Haematology/Oncology, Hospital for Sick Children, Toronto, ON M5G0A4, Canada; Department of Laboratory Medicine and Pathobiology, Faculty of Medicine, University of Toronto, Toronto, ON M5S1A8, Canada; Division of Hematology-Oncology, The Hospital for Sick Children, Department of Pediatrics, University of Toronto, Toronto, ON M5G0A4, Canada; Department of Medical Biophysics, Faculty of Medicine, University of Toronto, Toronto, ON M5G1L7, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2019.06.002DOI Listing
July 2019

Incidence of metastatic disease and survival among patients with newly diagnosed primary CNS tumors in the United States from 2004-2013.

J Cancer 2019 2;10(13):3037-3045. Epub 2019 Jun 2.

Department of Pediatric Neurosurgery, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai 200092, China.

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http://dx.doi.org/10.7150/jca.30624DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6590036PMC
June 2019

Subgroup-specific prognostic signaling and metabolic pathways in pediatric medulloblastoma.

BMC Cancer 2019 Jun 11;19(1):571. Epub 2019 Jun 11.

Division of Pediatric Neurosurgery, Seoul National University Children's Hospital, Department of Neurosurgery, Seoul National University College of Medicine, Seoul, Korea.

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http://dx.doi.org/10.1186/s12885-019-5742-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6560914PMC
June 2019

Anatomical predictors of conduction damage after transcatheter implantation of the aortic valve.

Open Heart 2019 9;6(1):e000972. Epub 2019 Apr 9.

Department of Ohio Heart and Vascular, The Christ Hospital and Lindner Center for Research and Education, Cincinnati, Ohio, USA.

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http://dx.doi.org/10.1136/openhrt-2018-000972DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6519402PMC
April 2019

Commentary: An unusual case of crossing coronaries.

Authors:
Michael D Taylor

J Thorac Cardiovasc Surg 2019 09 24;158(3):e111-e112. Epub 2019 Apr 24.

Department of Pediatric Cardiology, The Heart Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio. Electronic address:

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http://dx.doi.org/10.1016/j.jtcvs.2019.04.030DOI Listing
September 2019

Picosecond Infrared Laser Desorption Mass Spectrometry Identifies Medulloblastoma Subgroups on Intrasurgical Timescales.

Cancer Res 2019 05 19;79(9):2426-2434. Epub 2019 Mar 19.

Techna Institute for the Advancement of Technology for Health, University Health Network, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1158/0008-5472.CAN-18-3411DOI Listing
May 2019

Leptomeningeal dissemination: a sinister pattern of medulloblastoma growth.

J Neurosurg Pediatr 2019 Feb 15:1-9. Epub 2019 Feb 15.

3Cancer Research Program, Research Institute of the McGill University Health Center and Department of Surgery, McGill University, Montreal, Quebec, Canada.

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http://dx.doi.org/10.3171/2018.11.PEDS18506DOI Listing
February 2019

Medulloblastoma.

Nat Rev Dis Primers 2019 02 14;5(1):11. Epub 2019 Feb 14.

Hopp Children's Cancer Center Heidelberg (KiTZ), Heidelberg, Germany.

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http://dx.doi.org/10.1038/s41572-019-0063-6DOI Listing
February 2019

A functional genomics approach to identify pathways of drug resistance in medulloblastoma.

Acta Neuropathol Commun 2018 12 27;6(1):146. Epub 2018 Dec 27.

Department of Developmental and Stem Cell Biology and Regenerative Medicine, The Hospital for Sick Children, Toronto, Canada.

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http://dx.doi.org/10.1186/s40478-018-0652-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6307130PMC
December 2018

Dual Regulatory Functions of SUFU and Targetome of GLI2 in SHH Subgroup Medulloblastoma.

Dev Cell 2019 01 13;48(2):167-183.e5. Epub 2018 Dec 13.

Program in Developmental & Stem Cell Biology, The Hospital for Sick Children, Toronto, ON, Canada; Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada; Joint Institute of Genetics and Genomic Medicine, Zhejiang University and University of Toronto, Toronto, ON, Canada. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S15345807183093
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http://dx.doi.org/10.1016/j.devcel.2018.11.015DOI Listing
January 2019

Significance of molecular classification of ependymomas: C11orf95-RELA fusion-negative supratentorial ependymomas are a heterogeneous group of tumors.

Acta Neuropathol Commun 2018 12 4;6(1):134. Epub 2018 Dec 4.

Division of Brain Tumor Translational Research, National Cancer Center Research Institute, 5-1-1 Tsukiji, Chuo-ku, Tokyo, 104-0045, Japan.

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https://actaneurocomms.biomedcentral.com/articles/10.1186/s4
Publisher Site
http://dx.doi.org/10.1186/s40478-018-0630-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6278135PMC
December 2018

The influence of depth and a subsea pipeline on fish assemblages and commercially fished species.

PLoS One 2018 26;13(11):e0207703. Epub 2018 Nov 26.

The UWA Oceans Institute, The University of Western Australia, Crawley, Western Australia, Australia.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0207703PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6257935PMC
April 2019

Infusion of 5-Azacytidine (5-AZA) into the fourth ventricle or resection cavity in children with recurrent posterior Fossa Ependymoma: a pilot clinical trial.

J Neurooncol 2019 Jan 20;141(2):449-457. Epub 2018 Nov 20.

Developmental and Stem Cell Biology Program, The Arthur and Sonia Labatt Brain Tumour Center, Division of Neurosurgery, Hospital for Sick children, Toronto, ON, Canada.

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http://dx.doi.org/10.1007/s11060-018-03055-1DOI Listing
January 2019