Michael D Howell

Michael D Howell

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Michael D Howell

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Atopic dermatitis endotypes based on allergen sensitization, reactivity to Staphylococcus aureus antigens, and underlying systemic inflammation.

J Allergy Clin Immunol Pract 2019 Aug 17. Epub 2019 Aug 17.

MedImmune, LLC, Gaithersburg, MD; Currently Employed at Incyte Corporation, Wilmington, DE. Electronic address:

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http://dx.doi.org/10.1016/j.jaip.2019.08.013DOI Listing
August 2019

Treatment of atopic dermatitis with tralokinumab, an anti-IL-13 mAb.

J Allergy Clin Immunol 2019 Jan 12;143(1):135-141. Epub 2018 Jun 12.

Clinical Respiratory Management, MedImmune, Cambridge, United Kingdom.

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http://dx.doi.org/10.1016/j.jaci.2018.05.029DOI Listing
January 2019

Ensuring Fairness in Machine Learning to Advance Health Equity.

Ann Intern Med 2018 12 4;169(12):866-872. Epub 2018 Dec 4.

University of Chicago, Chicago, Illinois (M.H.C.).

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http://annals.org/article.aspx?doi=10.7326/M18-1990
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http://dx.doi.org/10.7326/M18-1990DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6594166PMC
December 2018

Implications of Centers for Medicare & Medicaid Services Severe Sepsis and Septic Shock Early Management Bundle and Initial Lactate Measurement on the Management of Sepsis.

Chest 2018 Aug 24;154(2):302-308. Epub 2018 May 24.

Department of Medicine, University of Chicago, Chicago, IL; Center for Healthcare Delivery Science and Innovation, Chicago, IL. Electronic address:

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http://dx.doi.org/10.1016/j.chest.2018.03.025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6113629PMC
August 2018

Building communities of respect in the intensive care unit.

Intensive Care Med 2018 08 30;44(8):1339-1341. Epub 2018 Jun 30.

Google Research, Google Inc., Mountain View, CA, USA.

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http://dx.doi.org/10.1007/s00134-018-5259-9DOI Listing
August 2018

Prevalence of Dyspnea Among Hospitalized Patients at the Time of Admission.

J Pain Symptom Manage 2018 07 22;56(1):15-22.e2. Epub 2018 Feb 22.

Division for Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA; Harvard Medical School, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1016/j.jpainsymman.2018.02.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6317868PMC
July 2018

Resolving the Productivity Paradox of Health Information Technology: A Time for Optimism.

JAMA 2018 Jul;320(1):25-26

Google, LLC, Mountain View, California.

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http://dx.doi.org/10.1001/jama.2018.5605DOI Listing
July 2018

The Practice of Respect in the ICU.

Am J Respir Crit Care Med 2018 06;197(11):1389-1395

14 Google Research, Google, Inc., Mountain View, California.

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http://dx.doi.org/10.1164/rccm.201708-1676CPDOI Listing
June 2018

Less Is More: Learning from Variation in Pulmonary Embolism Care.

Authors:
Michael D Howell

Ann Am Thorac Soc 2018 05;15(5):554-555

Google Research, Google LLC, Mountain View, California.

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http://dx.doi.org/10.1513/AnnalsATS.201802-113EDDOI Listing
May 2018

JAK/STAT inhibitors and other small molecule cytokine antagonists for the treatment of allergic disease.

Ann Allergy Asthma Immunol 2018 04 14;120(4):367-375. Epub 2018 Feb 14.

Incyte Corporation, Wilmington, Delaware.

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http://dx.doi.org/10.1016/j.anai.2018.02.012DOI Listing
April 2018

Management of ARDS in Adults.

JAMA 2018 02;319(7):711-712

Section of General Internal Medicine, University of Chicago, Chicago, Illinois.

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http://jama.jamanetwork.com/article.aspx?doi=10.1001/jama.20
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http://dx.doi.org/10.1001/jama.2018.0307DOI Listing
February 2018

The Critical Care Crisis of Opioid Overdoses in the United States.

Ann Am Thorac Soc 2017 Dec;14(12):1803-1809

3 Center for Healthcare Delivery Science and Innovation and.

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http://dx.doi.org/10.1513/AnnalsATS.201701-022OCDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5802515PMC
December 2017

Comparison of Hospital Resource Use and Outcomes Among Hospitalists, Primary Care Physicians, and Other Generalists.

JAMA Intern Med 2017 12;177(12):1781-1787

Center for Healthcare Delivery Science, Beth Israel Deaconess Medical Center, Boston, Massachusetts.

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http://dx.doi.org/10.1001/jamainternmed.2017.5824DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5820730PMC
December 2017

Quantifying the Mortality Impact of Do-Not-Resuscitate Orders in the ICU.

Crit Care Med 2017 Jun;45(6):1019-1027

1Clinical Research Center, Soroka University Medical Center and Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel. 2Department of Anesthesia, Critical Care and Pain Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA. 3Intensive Care Unit, Sir Charles Gairdner Hospital, Nedlands, Western Australia. 4The Harvard-MIT Division of Health Sciences & Technology, Massachusetts Institute of Technology, Cambridge, MA. 5Institute for Infocomm Research, Agency for Science, Technology and Research, Singapore. 6Center for Quality and the Section of Pulmonary and Critical Care, University of Chicago, Chicago, IL. 7Department of Pulmonary and Critical Care Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA.

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http://dx.doi.org/10.1097/CCM.0000000000002312DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5679223PMC
June 2017

Detecting Sepsis: Are Two Opinions Better Than One?

J Hosp Med 2017 04;12(4):256-258

Section of Hospital Medicine, University of Chicago Medical Center, Chicago, IL, USA.

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http://dx.doi.org/10.12788/jhm.2721DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5865604PMC
April 2017

Targeting the T Helper 2 Inflammatory Axis in Atopic Dermatitis.

Int Arch Allergy Immunol 2016 16;171(2):71-80. Epub 2016 Nov 16.

Department of Medicine, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, Brazil.

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http://dx.doi.org/10.1159/000451083DOI Listing
February 2017

Management of Sepsis and Septic Shock.

JAMA 2017 02;317(8):847-848

General Internal Medicine, University of Chicago, Chicago, Illinois.

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http://jama.jamanetwork.com/article.aspx?doi=10.1001/jama.20
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http://dx.doi.org/10.1001/jama.2017.0131DOI Listing
February 2017

Lean: Targeted Therapy for Care Delivery.

J Natl Compr Canc Netw 2017 02;15(2):271-274

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February 2017

Improving Pain Relief in Elder Patients (I-PREP): An Emergency Department Education and Quality Intervention.

J Am Geriatr Soc 2016 12 2;64(12):2566-2571. Epub 2016 Nov 2.

Section of Geriatrics and Palliative Medicine, University of Chicago, Chicago, Illinois.

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http://dx.doi.org/10.1111/jgs.14377DOI Listing
December 2016

Prevalence and Predictive Value of Dyspnea Ratings in Hospitalized Patients: Pilot Studies.

PLoS One 2016 12;11(4):e0152601. Epub 2016 Apr 12.

Department of Medicine, Division for Pulmonary, Critical Care, and Sleep Medicine, Beth Israel Deaconess Medical Center, Boston, Massachusetts, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0152601PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4829144PMC
August 2016

Extremes of shock index predicts death in trauma patients.

J Emerg Trauma Shock 2016 Jul-Sep;9(3):103-6

Department of Anesthesia, Critical Care, and Pain Medicine, Harvard Medical School, Beth Israel Deaconess Medical Center, Boston, MA, USA.

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http://dx.doi.org/10.4103/0974-2700.185272DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4960776PMC
August 2016

Antipsychotic utilization in the intensive care unit and in transitions of care.

J Crit Care 2016 06 30;33:119-24. Epub 2015 Dec 30.

Instructor of Medicine Harvard Medical School, Division of Pulmonary, Critical Care and Sleep Medicine, Beth Israel Deaconess Medical Center.

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http://dx.doi.org/10.1016/j.jcrc.2015.12.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4842336PMC
June 2016

Transcatheter Therapy for a Large Mobile Right Atrial Thrombus and Massive Pulmonary Embolism.

J Invasive Cardiol 2016 May;28(5):E49-51

University of Chicago Medicine, Department of Internal Medicine, Section of Cardiology, 5841 S. Maryland Ave MC 6080, Chicago, IL 60637 USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5396535PMC
May 2016

Standard work for room entry: Linking lean, hand hygiene, and patient-centeredness.

Healthc (Amst) 2016 Mar 11;4(1):45-51. Epub 2016 Jan 11.

Critical Care Quality, Silverman Institute for Healthcare Quality, Beth Israel Deaconess Medical Center, 330 Brookline Ave, Boston 02215, MA, United States.

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http://dx.doi.org/10.1016/j.hjdsi.2015.12.008DOI Listing
March 2016

Estimating duration of central venous catheter at time of insertion: Clinician judgment and clinical predictors.

J Crit Care 2015 Dec 22;30(6):1299-302. Epub 2015 Aug 22.

Department of Emergency Medicine, Beth Israel Deaconess Medical Center, Boston, MA 02215; Division of Critical Care, Department of Anesthesia Critical Care, Beth Israel Deaconess Medical Center, Boston, MA 02215. Electronic address:

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http://dx.doi.org/10.1016/j.jcrc.2015.08.013DOI Listing
December 2015

ICUs after surgery, mortality, and the Will Rogers effect.

Intensive Care Med 2015 Nov 7;41(11):1990-2. Epub 2015 Aug 7.

Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, Center for Healthcare Delivery Science, Beth Israel Deaconess Medical Center, Boston, USA.

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http://dx.doi.org/10.1007/s00134-015-4007-7DOI Listing
November 2015

Opportunities and Challenges for Reducing Hospital Revisits.

Ann Intern Med 2015 Nov;163(9):727

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http://dx.doi.org/10.7326/L15-5154DOI Listing
November 2015

Variation and Cost-effectiveness of Quality Measurement Programs. The Case of Sepsis Bundles.

Ann Am Thorac Soc 2015 Nov;12(11):1597-9

1 Center for Quality.

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http://dx.doi.org/10.1513/AnnalsATS.201509-625EDDOI Listing
November 2015

The utility of utility scores.

Ann Am Thorac Soc 2015 Jul;12(7):976-7

1 Center for Quality.

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http://dx.doi.org/10.1513/AnnalsATS.201505-262EDDOI Listing
July 2015

Seasonal variation in family member perceptions of physician competence in the intensive care unit: findings from one academic medical center.

Acad Med 2015 Apr;90(4):472-8

Dr. Stevens is a research fellow, Center for Healthcare Delivery Science, and clinical fellow, Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, Beth Israel Deaconess Medical Center, Boston, Massachusetts. Mr. Kachniarz is an MD candidate, Harvard Medical School, Boston, Massachusetts. Ms. O'Reilly is manager, Center for Healthcare Delivery Science, Department of Medicine, Beth Israel Deaconess Medical Center, Boston, Massachusetts. Dr. Howell is associate chief medical officer for clinical quality and associate professor of medicine, Section of Pulmonary and Critical Care, Department of Medicine, University of Chicago, Chicago, Illinois.

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http://dx.doi.org/10.1097/ACM.0000000000000553DOI Listing
April 2015

Intensivist-to-patient ratios in ICUs: is there a number?

Curr Opin Anaesthesiol 2015 Apr;28(2):172-9

aDivision of Pulmonary, Critical Care, and Sleep Medicine, The Alpert Medical School of Brown University, Rhode Island Hospital bCenter for Quality, and Section of Pulmonary/Critical Care Medicine, University of Chicago.

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http://dx.doi.org/10.1097/ACO.0000000000000170DOI Listing
April 2015

Trends in severity of illness on ICU admission and mortality among the elderly.

PLoS One 2014 3;9(4):e93234. Epub 2014 Apr 3.

Intensive Care Unit, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0093234PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3974713PMC
January 2015

Improving appropriateness of acid-suppressive medication use via computerized clinical decision support.

J Hosp Med 2015 Jan;10(1):41-5

Division of General Medicine and Primary Care, Beth Israel Deaconess Medical Center, and Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1002/jhm.2260DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4302762PMC
January 2015

Automated surveillance for ventilator-associated events.

Chest 2014 Dec;146(6):1612-1618

Center for Healthcare Delivery Science, Beth Israel Deaconess Medical Center, Boston, MA; Center for Quality, and Section of Pulmonary and Critical Care, Department of Medicine, University of Chicago, Chicago, IL.

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http://dx.doi.org/10.1378/chest.13-2255DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4251620PMC
December 2014

Strategies to prevent ventilator-associated pneumonia in acute care hospitals: 2014 update.

Infect Control Hosp Epidemiol 2014 Aug;35(8):915-36

Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, Massachusetts.

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http://dx.doi.org/10.1086/677144DOI Listing
August 2014

Reappraisal of routine oral care with chlorhexidine gluconate for patients receiving mechanical ventilation: systematic review and meta-analysis.

JAMA Intern Med 2014 May;174(5):751-61

Department of Anesthesiology and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland6Department of Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland7Department of Health Policy and Management, B.

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http://dx.doi.org/10.1001/jamainternmed.2014.359DOI Listing
May 2014

When policy gets it right: variability in u.s. Hospitals' diagnosis of ventilator-associated pneumonia*.

Crit Care Med 2014 Mar;42(3):497-503

1Department of Medicine, Division of Pulmonary, Critical Care, and Sleep Medicine, Beth Israel Deaconess Medical Center, Boston, MA. 2Center for Healthcare Delivery Science, Beth Israel Deaconess Medical Center, Boston, MA. 3Harvard Medical School, Boston, MA. 4Department of Medicine, Division of Infectious Diseases, Beth Israel Deaconess Medical Center, Boston, MA. 5Department of Anesthesia, Critical Care and Pain Medicine, Beth Israel Deaconess Medical Center, Boston, MA. 6Section of Pulmonary and Critical Care, Department of Medicine, University of Chicago, Chicago, IL.

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http://dx.doi.org/10.1097/CCM.0b013e3182a66903DOI Listing
March 2014

Structure, process, and annual ICU mortality across 69 centers: United States Critical Illness and Injury Trials Group Critical Illness Outcomes Study.

Crit Care Med 2014 Feb;42(2):344-56

1Division of Pulmonary and Critical Care, Johns Hopkins University, Baltimore, MD. 2Division of Pulmonary, Allergy, and Critical Care, Emory University, Atlanta, GA. 3Division of Pulmonary and Critical Care, Intermountain Medical Center and University of Utah, Salt Lake City, UT. 4Division of Pulmonary and Critical Care, University of Medicine and Dentistry of New Jersey, Newark, NJ. 5Division of Pulmonary, Critical Care, and Environmental Medicine, University of Missouri-Columbia, Columbia, MO. 6Division of Pulmonary and Critical Care, Meharry Medical College, Nashville, TN. 7Division of Allergy, Pulmonary, and Critical Care Medicine, Vanderbilt University School of Medicine, Nashville, TN. 8Division of Pulmonary, Critical Care, and Sleep Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA. 9Department of Surgical Critical Care, University of Maryland, Baltimore, MD. 10Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, Ohio State University, Cleveland, OH. 11Division of Acute Care Surgery, Department of Surgery, University of Michigan Health System, Ann Arbor, MI. 12Department of Anesthesiology and Critical Care Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY. 13Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Boston, MA. 14Division of Pulmonary and Critical Care Medicine, University of Rochester, Rochester, NY. 15INOVA Fairfax Hospital, Falls Church, VA. 16Suburban Hospital, Bethesda, MD. 17Section of Pulmonary and Critical Care Medicine, Yale University School of Medicine, New Haven, CT. 18Department of Anesthesia, Beth Israel Deaconess Medical Center, Boston, MA.

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http://dx.doi.org/10.1097/CCM.0b013e3182a275d7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4035482PMC
February 2014

Liberating brain-injured patients from mechanical ventilation. learning from healthcare delivery science.

Am J Respir Crit Care Med 2013 Oct;188(8):894-6

1 Center for Healthcare Delivery Science Beth Israel Deaconess Medical Center Boston, Massachusetts and Department of Medicine Beth Israel Deaconess Medical Center and Harvard Medical School Boston, Massachusetts.

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http://dx.doi.org/10.1164/rccm.201308-1486EDDOI Listing
October 2013

Miscount incidents: a novel approach to exploring risk factors for unintentionally retained surgical items.

Jt Comm J Qual Patient Saf 2013 Oct;39(10):468-74

Weill Cornell Medical College, New York City, NY, USA.

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October 2013

Elements of a high-quality inpatient consultation in the intensive care unit. A qualitative study.

Ann Am Thorac Soc 2013 Jun;10(3):220-7

Department of Medicine, Division of Pulmonary, Critical Care, and Sleep Medicine, Beth Israel Deaconess Medical Center, Boston, Massachusetts 02215, USA.

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http://dx.doi.org/10.1513/AnnalsATS.201212-120OCDOI Listing
June 2013

Risk factors for nosocomial gastrointestinal bleeding and use of acid-suppressive medication in non-critically ill patients.

J Gen Intern Med 2013 May 5;28(5):683-90. Epub 2013 Jan 5.

Division of General Medicine and Primary Care, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, USA.

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http://link.springer.com/10.1007/s11606-012-2296-x
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http://dx.doi.org/10.1007/s11606-012-2296-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3631055PMC
May 2013

Proton-pump inhibitor use is associated with low serum magnesium concentrations.

Kidney Int 2013 Apr 16;83(4):692-9. Epub 2013 Jan 16.

Department of Medicine, Beth Israel Deaconess Medical Center, Boston, Massachusetts 02215, USA.

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http://dx.doi.org/10.1038/ki.2012.452DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5682024PMC
April 2013

Estimated nursing workload for the implementation of ventilator bundles.

BMJ Qual Saf 2013 Apr 21;22(4):357-61. Epub 2013 Feb 21.

Division of Infectious Disease, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA.

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http://dx.doi.org/10.1136/bmjqs-2012-001372DOI Listing
April 2013

Lactate clearance as a predictor of mortality in trauma patients.

J Trauma Acute Care Surg 2013 Apr;74(4):999-1004

Division of Acute Care Surgery, Trauma and Surgical Critical Care, Department of Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA.

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http://dx.doi.org/10.1097/TA.0b013e3182858a3eDOI Listing
April 2013

Empirical relationships among oliguria, creatinine, mortality, and renal replacement therapy in the critically ill.

Intensive Care Med 2013 Mar 7;39(3):414-9. Epub 2012 Dec 7.

Department of Anesthesia, Critical Care and Pain Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, 1 Deaconess Rd. CC-470, Boston, MA 02215, USA.

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http://link.springer.com/10.1007/s00134-012-2767-x
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http://dx.doi.org/10.1007/s00134-012-2767-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3580030PMC
March 2013

The author replies.

Authors:
Michael D Howell

Crit Care Med 2013 Feb;41(2):e24

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http://dx.doi.org/10.1097/CCM.0b013e31827bf66bDOI Listing
February 2013

Sustained effectiveness of a primary-team-based rapid response system.

Crit Care Med 2012 Sep;40(9):2562-8

Silverman Institute for Healthcare Quality and Safety, Beth Israel Deaconess Medical Center, Boston, MA, USA.

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http://dx.doi.org/10.1097/CCM.0b013e318259007bDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3638079PMC
September 2012

Intensivist time allocation: economic and ethical issues surrounding how intensivists use their time.

Authors:
Michael D Howell

Semin Respir Crit Care Med 2012 Aug 8;33(4):401-12. Epub 2012 Aug 8.

Department of Medicine, Division of Pulmonary, Critical Care, and Sleep Medicine, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA.

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http://dx.doi.org/10.1055/s-0032-1322410DOI Listing
August 2012

Initial management of septic patients with hyperglycemia in the noncritical care inpatient setting.

Am J Med 2012 Jul 19;125(7):670-8. Epub 2012 May 19.

Department of Emergency Medicine, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA.

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http://dx.doi.org/10.1016/j.amjmed.2012.03.001DOI Listing
July 2012

Predictors and correlates of dissatisfaction with intensive care.

Crit Care Med 2012 May;40(5):1554-61

Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, and the Silverman Institute for Healthcare Quality and Safety, Beth Israel Deaconess Medical Center, Children's Hospital Boston, and Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1097/CCM.0b013e3182451c70DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3647885PMC
May 2012

Red cell distribution width and mortality in newly hospitalized patients.

Am J Med 2012 Mar;125(3):283-91

Department of Medicine, Division of Pulmonary, Critical Care, and Sleep Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA.

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http://dx.doi.org/10.1016/j.amjmed.2011.08.021DOI Listing
March 2012

Outcome of critically ill patients with acute kidney injury using the Acute Kidney Injury Network criteria.

Crit Care Med 2011 Dec;39(12):2659-64

Department of Anesthesia, Critical Care and Pain Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, USA.

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https://insights.ovid.com/crossref?an=00003246-201112000-000
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http://dx.doi.org/10.1097/CCM.0b013e3182281f1bDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3213281PMC
December 2011

Managing ICU throughput and understanding ICU census.

Authors:
Michael D Howell

Curr Opin Crit Care 2011 Dec;17(6):626-33

Silverman Institute for Healthcare Quality and Safety, Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1097/MCC.0b013e32834b3e6eDOI Listing
December 2011

Diabetes is not associated with increased mortality in emergency department patients with sepsis.

Ann Emerg Med 2011 Nov 16;58(5):438-44. Epub 2011 Jun 16.

Department of Emergency Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA.

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http://dx.doi.org/10.1016/j.annemergmed.2011.03.052DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3425373PMC
November 2011

International validation of the out-of-hospital cardiac arrest score in the United States.

Crit Care Med 2011 Jul;39(7):1670-4

Department of Medicine, Division of Pulmonary, Critical Care, and Sleep Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA.

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http://dx.doi.org/10.1097/CCM.0b013e318218a05bDOI Listing
July 2011

Acid-suppressive medication use and the risk for nosocomial gastrointestinal tract bleeding.

Arch Intern Med 2011 Jun 14;171(11):991-7. Epub 2011 Feb 14.

Division of General Medicine, Beth Israel Deaconess Medical Center, Brookline, MA 02446, USA.

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http://dx.doi.org/10.1001/archinternmed.2011.14DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3142477PMC
June 2011

Commentary: Is the glass half empty? Code blue training in the modern era.

Acad Med 2011 Jun;86(6):680-3

Silverman Institute for Healthcare Quality and Safety, Beth Israel Deaconess Medical Center, One Deaconess Road, Boston, MA 02215, USA.

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http://dx.doi.org/10.1097/ACM.0b013e318217e969DOI Listing
June 2011

Teamwork and leadership in cardiopulmonary resuscitation.

J Am Coll Cardiol 2011 Jun;57(24):2381-8

Medical Intensive Care Unit, University Hospital Basel, Basel, Switzerland.

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http://dx.doi.org/10.1016/j.jacc.2011.03.017DOI Listing
June 2011

Residents' and nurses' perceptions of team function in the medical intensive care unit.

J Crit Care 2011 Feb 19;26(1):104.e7-15. Epub 2010 Jun 19.

Harvard University PhD Program in Health Policy, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA.

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http://dx.doi.org/10.1016/j.jcrc.2010.04.003DOI Listing
February 2011

Proof of principle: the predisposition, infection, response, organ failure sepsis staging system.

Crit Care Med 2011 Feb;39(2):322-7

Pulmonary and Critical Care Division, Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1097/CCM.0b013e3182037a8eDOI Listing
February 2011

Specificity protein 1 is pivotal in the skin's antiviral response.

J Allergy Clin Immunol 2011 Feb 5;127(2):430-438.e1-2. Epub 2011 Jan 5.

Department of Pediatrics, National Jewish Health, Denver, Colo, USA.

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http://dx.doi.org/10.1016/j.jaci.2010.11.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3734863PMC
February 2011

Iatrogenic gastric acid suppression and the risk of nosocomial Clostridium difficile infection.

Arch Intern Med 2010 May;170(9):784-90

Silverman Institute for Healthcare Quality and Safety, Beth Israel Deaconess Medical Center, 330 Brookline Ave, Boston, MA 02215, USA.

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http://dx.doi.org/10.1001/archinternmed.2010.89DOI Listing
May 2010

IL-4 regulates skin homeostasis and the predisposition toward allergic skin inflammation.

J Immunol 2010 Mar 10;184(6):3186-90. Epub 2010 Feb 10.

Department of Pediatrics, Indiana University School of Medicine, Indianapolis, IN 46202, USA.

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http://dx.doi.org/10.4049/jimmunol.0901860DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2837507PMC
March 2010

Vaccinia virus-specific molecular signature in atopic dermatitis skin.

J Allergy Clin Immunol 2010 Jan;125(1):153-159.e28

Division of Allergy and Clinical Immunology, Johns Hopkins University, Baltimore, MD, USA.

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http://dx.doi.org/10.1016/j.jaci.2009.10.024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2814071PMC
January 2010

A 37-year-old man trying to choose a high-quality hospital: review of hospital quality indicators.

Authors:
Michael D Howell

JAMA 2009 Dec 3;302(21):2353-60. Epub 2009 Nov 3.

Silverman Institute for Health Care Quality and Safety, Beth Israel Deaconess Medical Center, 330 Brookline Ave, Boston, MA 02215, USA.

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http://dx.doi.org/10.1001/jama.2009.1684DOI Listing
December 2009

Ceragenins: a class of antiviral compounds to treat orthopox infections.

J Invest Dermatol 2009 Nov 11;129(11):2668-75. Epub 2009 Jun 11.

Division of Allergy and Immunology, Department of Pediatrics, National Jewish Health, Denver, Colorado 80206, USA.

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http://dx.doi.org/10.1038/jid.2009.120DOI Listing
November 2009

Lactate: finally ready for prime time?

Authors:
Michael D Howell

Crit Care Med 2009 Oct;37(10):2858-9

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http://dx.doi.org/10.1097/CCM.0b013e3181ad79caDOI Listing
October 2009

Vaccinia virus inoculation in sites of allergic skin inflammation elicits a vigorous cutaneous IL-17 response.

Proc Natl Acad Sci U S A 2009 Sep 17;106(35):14954-9. Epub 2009 Aug 17.

Division of Immunology, Children's Hospital, Harvard Medical School, Boston, MA 02115, USA.

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http://dx.doi.org/10.1073/pnas.0904021106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2736417PMC
September 2009

Cytokine modulation of atopic dermatitis filaggrin skin expression.

J Allergy Clin Immunol 2009 Sep;124(3 Suppl 2):R7-R12

Department of Pediatrics, National Jewish Medical and Research Center, Denver, CO 80206, USA.

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http://dx.doi.org/10.1016/j.jaci.2009.07.012DOI Listing
September 2009

Inhibition of S100A11 gene expression impairs keratinocyte response against vaccinia virus through downregulation of the IL-10 receptor 2 chain.

J Allergy Clin Immunol 2009 Aug 3;124(2):270-7, 277.e1. Epub 2009 Jul 3.

Department of Pediatrics, National Jewish Health, Denver, Colo 80206, USA.

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http://dx.doi.org/10.1016/j.jaci.2009.05.002DOI Listing
August 2009

Acid-suppressive medication use and the risk for hospital-acquired pneumonia.

JAMA 2009 May;301(20):2120-8

Division of General Medicine and Primary Care, Beth Israel Deaconess Medical Center, 330 Brookline Ave, Boston, MA 02215, USA.

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http://dx.doi.org/10.1001/jama.2009.722DOI Listing
May 2009

Th2 cytokines act on S100/A11 to downregulate keratinocyte differentiation.

J Invest Dermatol 2008 Sep 3;128(9):2248-58. Epub 2008 Apr 3.

Department of Pediatrics, National Jewish Medical and Research Center, Denver, Colorado 80206, USA.

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http://dx.doi.org/10.1038/jid.2008.74DOI Listing
September 2008

The costs and cost-effectiveness of an integrated sepsis treatment protocol.

Crit Care Med 2008 Apr;36(4):1168-74

Department of Anesthesia, Critical Care and Pain Medicine, Beth Israel Deaconess Medical Center, and Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1097/CCM.0b013e318168f649DOI Listing
April 2008

Loricrin and involucrin expression is down-regulated by Th2 cytokines through STAT-6.

Clin Immunol 2008 Mar 31;126(3):332-7. Epub 2007 Dec 31.

Department of Pediatrics, National Jewish Medical and Research Center, 1400 Jackson Street, Denver, CO 80206, USA.

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http://dx.doi.org/10.1016/j.clim.2007.11.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2275206PMC
March 2008

Impaired immune response to vaccinia virus inoculated at the site of cutaneous allergic inflammation.

J Allergy Clin Immunol 2007 Dec 24;120(6):1382-8. Epub 2007 Sep 24.

Department of Pediatrics, Division of Allergy and Immunology, Children's Hospital, Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1016/j.jaci.2007.08.004DOI Listing
December 2007