Michael D Hogarty

Michael D Hogarty

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Michael D Hogarty

Michael D Hogarty

Publications by authors named "Michael D Hogarty"

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The challenge of defining "ultra-high-risk" neuroblastoma.

Pediatr Blood Cancer 2019 Apr 26;66(4):e27556. Epub 2018 Nov 26.

Hospital for Sick Children and University of Toronto, Toronto, Canada.

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http://doi.wiley.com/10.1002/pbc.27556
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http://dx.doi.org/10.1002/pbc.27556DOI Listing
April 2019

Statistical Framework in Support of a Revised Children's Oncology Group Neuroblastoma Risk Classification System.

JCO Clin Cancer Inform 2018 12;2:1-15

Arlene Naranjo, University of Florida, Gainesville, FL; Meredith S. Irwin, Hospital for Sick Children, Toronto, ON, Canada; Michael D. Hogarty, University of Pennsylvania, Philadelphia, PA; Susan L. Cohn, The University of Chicago, Chicago, IL; Julie R. Park, University of Washington, Seattle, WA; and Wendy B. London, Dana-Farber/Boston Children's Cancer and Blood Disorders Center and Harvard Medical School, Boston, MA.

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http://dx.doi.org/10.1200/CCI.17.00140DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6421832PMC
December 2018

Myc, Oncogenic Protein Translation, and the Role of Polyamines.

Med Sci (Basel) 2018 May 25;6(2). Epub 2018 May 25.

Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.3390/medsci6020041DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6024823PMC
May 2018

Characterisation of the p53 pathway in cell lines established from TH-MYCN transgenic mouse tumours.

Int J Oncol 2018 Mar 31;52(3):967-977. Epub 2018 Jan 31.

Wolfson Childhood Cancer Research Centre, Northern Institute for Cancer Research, Newcastle University, Newcastle upon Tyne NE1 7RU, UK.

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http://dx.doi.org/10.3892/ijo.2018.4261DOI Listing
March 2018

Polyamine Antagonist Therapies Inhibit Neuroblastoma Initiation and Progression.

Clin Cancer Res 2016 Sep 24;22(17):4391-404. Epub 2016 Mar 24.

Division of Oncology, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania. Department of Pediatrics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania.

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http://dx.doi.org/10.1158/1078-0432.CCR-15-2539DOI Listing
September 2016

EGFR signaling defines Mcl⁻1 survival dependency in neuroblastoma.

Cancer Biol Ther 2015 ;16(2):276-86

a Division of Hematology/Oncology; Aflac Children's Cancer and Blood Disorders Center ; Children's Healthcare of Atlanta ; Atlanta , GA USA.

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http://dx.doi.org/10.1080/15384047.2014.1002333DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4622539PMC
November 2015

Translational development of difluoromethylornithine (DFMO) for the treatment of neuroblastoma.

Transl Pediatr 2015 Jul;4(3):226-38

1 Division of Infectious Diseases, The Children's Hospital of Philadelphia, Philadelphia, USA ; 2 Department of Pediatrics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, USA ; 3 Children's Cancer Institute Australia, Sydney, Australia ; 4 Lankenau Institute for Medical Research, Wynnewood, USA ; 5 Division of Oncology, The Children's Hospital of Philadelphia, Philadelphia, USA.

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http://dx.doi.org/10.3978/j.issn.2224-4336.2015.04.06DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4729051PMC
July 2015

Expanding MYCN's reach in oncogenic transcription.

J Natl Cancer Inst 2015 Apr 24;107(6):djv122. Epub 2015 Apr 24.

: Division of Oncology, The Children's Hospital of Philadelphia, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA.

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http://dx.doi.org/10.1093/jnci/djv122DOI Listing
April 2015

Age-dependent prognostic effect by Mitosis-Karyorrhexis Index in neuroblastoma: a report from the Children's Oncology Group.

Pediatr Dev Pathol 2014 Nov-Dec;17(6):441-9. Epub 2014 Sep 10.

1 Department of Pathology & Laboratory Medicine, Children's Hospital Los Angeles, and University of Southern California Keck School of Medicine, 4650 Sunset Boulevard, MS #43, Los Angeles, CA 90027, USA.

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http://dx.doi.org/10.2350/14-06-1505-OA.1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4340697PMC
March 2015

TWIST1 is a direct transcriptional target of MYCN and MYC in neuroblastoma.

Cancer Lett 2015 Feb 1;357(1):412-418. Epub 2014 Dec 1.

Université Lyon 1, F-69000 Lyon, France; Centre Léon Bérard, F-69008 Lyon, France; Pôle des Sciences Cliniques, Lyon, F-69008, France. Electronic address:

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http://dx.doi.org/10.1016/j.canlet.2014.11.056DOI Listing
February 2015

Chronic myelogenous leukemia and retinopathy treated with imatinib.

Retin Cases Brief Rep 2011 ;5(4):366-8

From the *Department of Ophthalmology, Scheie Eye Institute, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania; †Division of Oncology; and ‡Neuro-Ophthalmology Service, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.

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http://dx.doi.org/10.1097/ICB.0b013e31821cdf29DOI Listing
November 2014

ALK mutations confer differential oncogenic activation and sensitivity to ALK inhibition therapy in neuroblastoma.

Cancer Cell 2014 Nov 10;26(5):682-94. Epub 2014 Nov 10.

Department of Pediatrics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104, USA; Division of Oncology and Center for Childhood Cancer Research, The Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2014.09.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4269829PMC
November 2014

The stress protein BAG3 stabilizes Mcl-1 protein and promotes survival of cancer cells and resistance to antagonist ABT-737.

J Biol Chem 2013 Mar 22;288(10):6980-90. Epub 2013 Jan 22.

Department of Biochemistry, Vanderbilt Institute of Chemical Biology, Center in Molecular Toxicology, Vanderbilt University School of Medicine, Nashville, Tennessee 37232-0146, USA.

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http://www.jbc.org/content/288/10/6980.full.pdf
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http://www.jbc.org/cgi/doi/10.1074/jbc.M112.414177
Publisher Site
http://dx.doi.org/10.1074/jbc.M112.414177DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3591608PMC
March 2013

Integrated genomic analyses identify ARID1A and ARID1B alterations in the childhood cancer neuroblastoma.

Nat Genet 2013 Jan 2;45(1):12-7. Epub 2012 Dec 2.

Ludwig Center for Cancer Genetics and Therapeutics, The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, Maryland, USA.

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http://dx.doi.org/10.1038/ng.2493DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3557959PMC
January 2013

ATF4 regulates MYC-mediated neuroblastoma cell death upon glutamine deprivation.

Cancer Cell 2012 Nov;22(5):631-44

Abramson Family Cancer Research Institute, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1016/j.ccr.2012.09.021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3510660PMC
November 2012

Polyamine pathway inhibition as a novel therapeutic approach to treating neuroblastoma.

Front Oncol 2012 16;2:162. Epub 2012 Nov 16.

Children's Cancer Institute Australia for Medical Research, Lowy Cancer Research Centre Sydney, NSW, Australia.

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http://dx.doi.org/10.3389/fonc.2012.00162DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3499881PMC
November 2012

PI3King on MYCN to improve neuroblastoma therapeutics.

Cancer Cell 2012 Feb;21(2):145-7

Division of Oncology, Children's Hospital of Philadelphia, Perelman School of Medicine University of Pennsylvania, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1016/j.ccr.2012.01.018DOI Listing
February 2012

IL-17A in LCH: systemic biomarker, local factor, or none of the above?

Mol Ther 2011 Aug;19(8):1405-6

Division of Oncology, The Children's Hospital of Philadelphia, Pennsylvania 19104, USA.

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http://dx.doi.org/10.1038/mt.2011.150DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3149169PMC
August 2011

Pediatric horner syndrome.

Arch Ophthalmol 2011 Aug;129(8):1108-9; author reply 1109

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http://dx.doi.org/10.1001/archophthalmol.2011.201DOI Listing
August 2011

Langerhans cell histiocytosis of the uvea with neovascular glaucoma: diagnosis by fine-needle aspiration biopsy and management with intraocular bevacizumab and brachytherapy.

J AAPOS 2010 Dec;14(6):534-7

Ocular Oncology Service, Wills Eye Institute, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA.

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http://dx.doi.org/10.1016/j.jaapos.2010.10.007DOI Listing
December 2010

Mcl1 becomes ubiquitin-ous: new opportunities to antagonize a pro-survival protein.

Cell Res 2010 Apr;20(4):391-3

Division of Oncology, The Children's Hospital of Philadelphia, Department of Pediatrics, The University of Pennsylvania School of Medicine, Colket Translational Research Building, Room 3020, 3501 Civic Center Boulevard, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1038/cr.2010.37DOI Listing
April 2010

Clinicopathological characteristics of ganglioneuroma and ganglioneuroblastoma: a report from the CCG and COG.

Pediatr Blood Cancer 2009 Oct;53(4):563-9

Department of Pathology and Laboratory Medicine, Childrens Hospital Los Angeles, University of Southern California Keck School of Medicine, Los Angeles, California 90027, USA.

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http://dx.doi.org/10.1002/pbc.22106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2730988PMC
October 2009

Disrupting polyamine homeostasis as a therapeutic strategy for neuroblastoma.

Clin Cancer Res 2009 Oct 29;15(19):5956-61. Epub 2009 Sep 29.

Division of Oncology, The Children's Hospital of Philadelphia and Department of Pediatrics, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104-4318, USA.

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http://dx.doi.org/10.1158/1078-0432.CCR-08-3213DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2923453PMC
October 2009

Mcl1 downregulation sensitizes neuroblastoma to cytotoxic chemotherapy and small molecule Bcl2-family antagonists.

Cancer Biol Ther 2009 Aug 8;8(16):1587-95. Epub 2009 Aug 8.

Division of Oncology, The Children's Hospital of Philadelphia, Philadelphia, PA 19104-4318, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3770183PMC
http://dx.doi.org/10.4161/cbt.8.16.8964DOI Listing
August 2009

Small-molecule BH3 mimetics to antagonize Bcl-2-homolog survival functions in cancer.

Curr Opin Investig Drugs 2009 Jun;10(6):559-71

The Children's Hospital of Philadelphia, Division of Oncology, 3615 Civic Center Boulevard, Philadelphia, PA 19104-4318, USA.

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June 2009

Neuroblastoma.

Lancet 2007 Jun;369(9579):2106-20

Children's Hospital of Philadelphia and University of Pennsylvania School of Medicine, Philadelphia, PA 19104-4318, USA.

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http://dx.doi.org/10.1016/S0140-6736(07)60983-0DOI Listing
June 2007

Cutaneous metastatic chordoma with concomitant tuberous sclerosis.

J Am Acad Dermatol 2006 Aug;55(2 Suppl):S6-10

Geisinger Medical Center, Danville.

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http://dx.doi.org/10.1016/j.jaad.2005.08.061DOI Listing
August 2006

Mutations in PIK3CA are infrequent in neuroblastoma.

BMC Cancer 2006 Jul 5;6:177. Epub 2006 Jul 5.

Division of Oncology, The Children's Hospital of Philadelphia; Philadelphia, PA, USA.

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http://dx.doi.org/10.1186/1471-2407-6-177DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1533846PMC
July 2006

Targeting programmed cell death pathways with experimental therapeutics: opportunities in high-risk neuroblastoma.

Cancer Lett 2005 Oct;228(1-2):133-41

Division of Oncology, The Children's Hospital of Philadelphia, University of Pennsylvania School of Medicine, 9 North ARC, 3615 Civic Center Boulevard, Philadelphia, PA 19104-4318, USA.

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http://dx.doi.org/10.1016/j.canlet.2005.01.048DOI Listing
October 2005

Definition and characterization of a region of 1p36.3 consistently deleted in neuroblastoma.

Oncogene 2005 Apr;24(16):2684-94

Division of Oncology, The Children's Hospital of Philadelphia, 3516 Civic Center Blvd, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1038/sj.onc.1208306DOI Listing
April 2005

Expression of a MYCN-interacting isoform of the tumor suppressor BIN1 is reduced in neuroblastomas with unfavorable biological features.

Clin Cancer Res 2003 Aug;9(9):3345-55

Department of Pediatric Surgery, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.

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August 2003

The requirement for evasion of programmed cell death in neuroblastomas with MYCN amplification.

Cancer Lett 2003 Jul;197(1-2):173-9

Division of Oncology, The Children's Hospital of Philadelphia and the Department of Pediatrics, University of Pennsylvania School of Medicine, Philadelphia, PA 19104-4318, USA.

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http://dx.doi.org/10.1016/s0304-3835(03)00103-4DOI Listing
July 2003

ID2 expression is not associated with MYCN amplification or expression in human neuroblastomas.

Cancer Res 2003 Apr;63(7):1631-5

Division of Oncology, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania 19104, USA.

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April 2003

No evidence for the presence of an imprinted neuroblastoma suppressor gene within chromosome sub-band 1p36.3.

Cancer Res 2002 Nov;62(22):6481-4

Division of Oncology, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania 19104-4318, USA.

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November 2002

Evidence for a hereditary neuroblastoma predisposition locus at chromosome 16p12-13.

Cancer Res 2002 Nov;62(22):6651-8

Department of Pediatrics, University of Pennsylvania School of Medicine and Children's Hospital of Philadelphia, Abramson Pediatric Research Center, Philadelphia, Pennsylvania 19104-4318, USA.

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November 2002